id author title date pages extension mime words sentences flesch summary cache txt cord-324480-7u5lh4jx Sharma, A. Structural stability of SARS-CoV-2 degrades with temperature 2020-10-14 .txt text/plain 1541 88 51 Here we have used atomic force microscopy to examine the structural stability of individual SARS-CoV-2 virus like particles at different temperatures. This is consistent with other existing non-mechanistic studies of viral infectivity, provides a single particle perspective on viral seasonality, and strengthens the case for a resurgence of COVID-19 in winter. However an understanding of how SARS-CoV-2 survives different environmental conditions is still incomplete and mechanisms of virus particle degradation are poorly mapped out. A key challenge in studying SARS-CoV-2 is the extreme level of threat associated with the live virus and the resultant need for high safety standards for such work. Here we used this technology to study the stability of the viral envelope and associated proteins (M, E, and S) under different environmental conditions. Environmental stability of SARS-CoV-2 on different types of surfaces under indoor and seasonal climate conditions ./cache/cord-324480-7u5lh4jx.txt ./txt/cord-324480-7u5lh4jx.txt