id author title date pages extension mime words sentences flesch summary cache txt cord-325473-hrdanbn1 Ghahremanpour, Mohammad M. Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2 2020-08-28 .txt text/plain 2915 205 56 2000 approved drugs to seek inhibitors of the main protease (Mpro) of SARS-CoV-2, the virus responsible for COVID-19. 5 Thus, M pro is viewed as a promising target for anti SARS-CoV-2 drug design; it has been the focus of several studies since the pandemic has emerged. For instance, a molecular docking study suggested remdesivir as a potential therapeutic that could be used against SARS-CoV-2, 10 which was supported experimentally by an EC50 value of 23 μM in an infected-cell assay. Structural Basis for the Inhibition of SARS-CoV-2 Main Protease by Antineoplastic Drug Carmofur Crystal Structure of SARS-CoV-2 Main Protease Provides a Basis for Design of Improved α-Ketoamide Inhibitors Prediction of Novel Inhibitors of the Main Protease (M-pro) of SARS-CoV-2 through Consensus Docking and Drug Reposition Structure-based Design of Antiviral Drug Candidates Targeting the SARS-CoV-2 Main Protease Targeting the SARS-CoV-2 Main Protease to Repurpose Drugs for ./cache/cord-325473-hrdanbn1.txt ./txt/cord-325473-hrdanbn1.txt