id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-328644-odtue60a	Comandatore, Francesco	Insurgence and worldwide diffusion of genomic variants in SARS-CoV-2 genomes	2020-05-28		.txt	text/plain	6535	301	50	These variants might arise during the spread of the epidemic, as viruses are known for their high frequency of mutation, particularly in single stranded RNA viruses -as in the case of SARS-CoV-2 (Sanjuán and Domingo-Calap 2016) , which has a single, positive-strand RNA genome. To have a better insight on the history and spread of the COVID-19 pandemic in Italy and thanks to the sequences deposited in the Gisaid database, we identified 7 non synonymous mutations that are differentially frequent in Italian SARS-CoV-2 strains respect to strains circulating globally. Our analysis allowed us to identify 7 positions in four proteins that present drastic changes in amino acid frequencies when comparing Italian sequences with worldwide sequences available on Gisaid.org on April, 10, 2020 ( Figure 1 ).	./cache/cord-328644-odtue60a.txt	./txt/cord-328644-odtue60a.txt