id author title date pages extension mime words sentences flesch summary cache txt cord-328695-nptfd6c2 Tengs, Torstein A mobile genetic element in the SARS-CoV-2 genome is shared with multiple insect species 2020-06-29 .txt text/plain 1969 102 51 title: A mobile genetic element in the SARS-CoV-2 genome is shared with multiple insect species We document here the presence of s2m, a highly conserved, mobile genetic element with unknown function, in both the SARS-CoV-2 genome and a large number of insect genomes. Although s2m is not universally present among coronaviruses and appears to undergo horizontal transfer, the high sequence conservation and universal presence of s2m among isolates of SARS-CoV-2 indicate that, when present, the element is essential for viral function. The presence of s2m in the SARS-CoV-2 genome (GenBank accession MN908947, position 29727-29768) and other members of this group is probably the result of a single horizontal transfer event, predating the divergence of the SARS-related viruses (Tengs, et al. The insect species that contain s2m (and the associated protein) are distantly related, indicating either a deep evolutionary origin with multiple losses or that this genetic construct is also a mobile element, perhaps using viruses as a vector . ./cache/cord-328695-nptfd6c2.txt ./txt/cord-328695-nptfd6c2.txt