id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-329129-t84pu00z	Zuo, J	Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection	2020-11-02		.txt	text/plain	3486	175	50	We analysed the magnitude and phenotype of the SARS-CoV-2 cellular immune response in 100 donors at six months following primary infection and related this to the profile of antibody level against spike, nucleoprotein and RBD over the previous six months. In conclusion, our data are reassuring that functional SARS-CoV-2-specific T-cell responses are retained at six months following infection although the magnitude of this response is related to the clinical features of primary infection. In this study we characterised SARS-CoV-2-specific T cell immune responses in a cohort of 100 donors at 6-months post-infection. Peptide pools from a range of viral proteins, including spike, nucleoprotein and membrane protein, were used to stimulate fresh PBMC and the magnitude of the global SARS-CoV-2-specific T-cell response was determined. Here we undertook, to our knowledge, the first assessment of the SARS-CoV-2-specific T cell immune response at six months following primary infection in a unique cohort of healthy adults with asymptomatic or mild-to-moderate COVID-19.	./cache/cord-329129-t84pu00z.txt	./txt/cord-329129-t84pu00z.txt