id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334300-hnrmaytm	Ventura Fernandes, Bianca H	Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction	2020-10-20		.txt	text/plain	1799	126	50	Establishing new experimental animal models to assess the safety and immune response to the antigen used in the development of COVID-19 vaccine is an imperative issue. Based on the advantages of using zebrafish as a model in research, herein we suggest doing this to test the safety of the putative vaccine candidates and to study immune response against the virus. Based on the in vivo and in silico results presented here, we propose the zebrafish as a model for translational research into the safety of the vaccine and the immune response of the vertebrate organism to the SARS-CoV-2 virus. 169 In the global task to develop the vaccine and possible therapeutic approaches for 170 COVID-19, several animal models have been proposed, such as mice 10 , hACE2 171 transgenic mice 11 , alpaca 12 , golden Syrian hamsters, ferrets, dogs, pigs, chickens, and 172 cats 9 , and species of non-human primates 10 .	./cache/cord-334300-hnrmaytm.txt	./txt/cord-334300-hnrmaytm.txt