id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-338734-laeocs3j	Lima, Amorce	Validation and Comparison of a Modified CDC Assay with two Commercially Available Assays for the Detection of SARS-CoV-2 in Respiratory Specimen	2020-06-30		.txt	text/plain	2533	141	61	In silico analysis and clinical sample testing showed that the primesr/probes designed by the CDC were specific to the SARS-CoV-2 as they accurately detected all reactive samples with an assay LoD of 200 copies/ml. A 149 series of two-fold dilutions of SARS-CoV-2 strain USA_WA1/2020 RNA were spiked in pooled 150 sputum at concentrations of 800 copies/ml to 0.05 copy/ml in order to determine the limit of 151 detection (LoD) of the assay. On the other hand, the average Ct values difference between 235 samples run within 2 days between DiaSorin Simplexa Covid 19 Direct assay and the modified 236 CDC SARS-CoV-2 assay was -2.42, and -6.0 between samples run within 5 days. In this study, we validated a modified CDC SARS-CoV-2 assay and compared its 263 performance to two commercial automated sample-to-answer assays for the detection of SARS-264 The difference is even greater 286 in samples that were run 5 days after the routine testing on the modified CDC SARS-CoV-2 287 assay.	./cache/cord-338734-laeocs3j.txt	./txt/cord-338734-laeocs3j.txt