id author title date pages extension mime words sentences flesch summary cache txt cord-340432-vm6m0kb4 Srivastava, Sukrit Computationally validated SARS-CoV-2 CTL and HTL Multi-Patch Vaccines designed by reverse epitomics approach, shows potential to cover large ethnically distributed human population worldwide 2020-09-06 .txt text/plain 2661 199 54 title: Computationally validated SARS-CoV-2 CTL and HTL Multi-Patch Vaccines designed by reverse epitomics approach, shows potential to cover large ethnically distributed human population worldwide Methodology A novel reverse epitomics approach, "overlapping-epitope-clusters-to-patches" method is utilized to identify multiple antigenic regions from the SARS-CoV-2 proteome. Multi-Patch Vaccine designing to combat SARS-CoV-2 infection by reverse epitomics approach, "Overlapping-epitope-clusters-to-patches" method. In the present study, we have reported a novel method to design a 1170 vaccine against SARS-CoV-2 by utilizing multiple antigenic patches from the viral 1171 proteins. The designed MPVs from the antigenic patches of SARS-CoV-2 proteins 1182 have several advantages over to the subunit and multi-epitope based vaccines. Design of multi epitope-based peptide vaccine against E 1409 protein of human 2019-nCoV: An immunoinformatics approach Multi-epitope based peptide 1549 vaccine design against SARS-CoV-2 using its spike protein In silico approach for designing of a multi-epitope based 1587 vaccine against novel Coronavirus (SARS-COV-2) ./cache/cord-340432-vm6m0kb4.txt ./txt/cord-340432-vm6m0kb4.txt