id author title date pages extension mime words sentences flesch summary cache txt cord-343586-28ezisog Rocca, MarĂ­a Florencia A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs 2020-05-07 .txt text/plain 1498 78 47 title: A Combined approach of MALDI-TOF Mass Spectrometry and multivariate analysis as a potential tool for the detection of SARS-CoV-2 virus in nasopharyngeal swabs Here, we exploit the potential of mass spectrometry technology combined with machine learning algorithms as an alternative fast tool for SARS-CoV-2 detection from nasopharyngeal swabs samples. According to our preliminary results, mass spectrometry-based methods combined with multivariate analysis showed an interesting potential as a complementary diagnostic tool and further steps should be focused on sample preparation protocols and the improvement of the technology applied. These preliminary results suggest that MALDI-TOF MS coupled with ClinProTools software represents an interesting alternative as a screening tool for diagnosis of SARS-CoV-2, especially because of the good performance and accuracy obtained with samples in which viral presence was not detected. ./cache/cord-343586-28ezisog.txt ./txt/cord-343586-28ezisog.txt