id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347441-8ow952d8	Parvez, Md Sorwer Alam	Genetic analysis of SARS-CoV-2 isolates collected from Bangladesh: insights into the origin, mutation spectrum, and possible pathomechanism	2020-06-07		.txt	text/plain	1027	75	62	title: Genetic analysis of SARS-CoV-2 isolates collected from Bangladesh: insights into the origin, mutation spectrum, and possible pathomechanism Molecular docking analysis to evaluate the effect of the mutations on the interaction between the viral spike proteins and the human ACE2 receptor, though no significant interaction was observed. This study provides some preliminary insights into the origin of Bangladeshi SARS-CoV-2 isolates, mutation spectrum and its possible pathomechanism, which may give an essential clue for designing therapeutics and management of COVID-19 in Bangladesh. As many of the Bangladeshi people return during the COVID-19 39 outbreak mainly from China, India, Saudi Arabia, Spain, Italy, Japan, Qatar, Canada, Kuwait, USA, 40 France, Sweden, and Switzerland, the first deposited genome sequence of those countries were also 41 retrieved. In total, three models were generated using the template PDB ID: 6VSB; one model for the spike protein 118 of reference strain, and the two others were for two different mutant isolates from Bangladesh (Fig 3) .	./cache/cord-347441-8ow952d8.txt	./txt/cord-347441-8ow952d8.txt