id author title date pages extension mime words sentences flesch summary cache txt cord-347804-kxhasabe Luo, Ruibang Tracking cytosine depletion in SARS-CoV-2 2020-10-26 .txt text/plain 1084 69 63 Results We built a website to track the composition change of mono-, di-, and tri-nucleotide of SARS-CoV-2 over time. Using 137,315 SARS-CoV-2 strains collected in ten months, we observed cytosine depletion at a rate of about one cytosine loss per month from the whole genome. We built an interactive website at http://www.bio8.cs.hku.hk/sarscov2 to show the mono-, di-, and tri-nucleotide composition trends of the whole genome and single genes. In Table 1 , we first compared the composition of nucleotides in multiple coronaviruses, including SARS-CoV-2 (an average of 76 strands collected from Dec 20, 2019 to Feb 15, 2020), SARS, MERS, and four that causes a common cold. Compared to SARS-CoV-2, which we assumed a relative mortality level of 3, the percentage of cytosine is lower in almost all of the eleven genes in the four common cold coronaviruses with a lower mortality level 1. The results are available on an interactive website at http://www.bio8.cs.hku.hk/sarscov2. ./cache/cord-347804-kxhasabe.txt ./txt/cord-347804-kxhasabe.txt