id author title date pages extension mime words sentences flesch summary cache txt cord-350627-4pgish5x Zhao, Yu Single-cell RNA expression profiling of ACE2,thereceptor of SARS-CoV-2 2020-01-26 .txt text/plain 1865 129 56 Here based on the public database and the state-of-the-art single-cell RNA-Seq technique, we analyzed the ACE2 RNA expression profile in the normal human lungs. These studies showed that in normal human lung, ACE2 is mainly expressed by type II and type I alveolar epithelial cells. In total, we analyzed 43,134 cells derived from normal lung tissue of To further understand the special population of ACE2-expressing AT2, we performed gene ontology enrichment analysis to study which biological processes are involved with this cell population by comparing them with the AT2 cells not expressing ACE2. Of note, the 2 male donors have a higher ACE2-expressing cell ratio than all other 6 female author/funder. We also noticed that the only Asian donor (male) has a much higher ACE2Altogether, in the current study, we report the RNA expression profile of ACE2 in the human lung at single-cell resolution. https://doi.org/10.1101/2020.01.26.919985 doi: bioRxiv preprint author/funder. ./cache/cord-350627-4pgish5x.txt ./txt/cord-350627-4pgish5x.txt