id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334123-wb45ww7f	Schimmel, Paul	RNA pseudoknots that interact with components of the translation apparatus	1989-07-14		.txt	text/plain	3334	169	60	A third and earlier study proposed that an RNA pseudoknot is recognized by a DNA binding protein that autogenously regulates translation of its mRNA (McPheeters et al., 1988) . The tRNA-like structures at the 3' ends of plant viral RNAs provide one example where the pseudoknot format may be necessary to form a substrate that is specifically recognized by an enzyme. Previous structural mapping experiments by Draper and co-workers suggested a model for the 5' region of the mRNA which constitutes the S4 binding site; it envisions a hairpin helix and loop that encompasses nucleotides 19 to 72. The second study provides evidence that pseudoknot formation in a viral mRNA is required for frameshift suppression of a termination codon that, in turn, allows a fusion protein to be synthesized from two overlapping reading frames. This element encodes a stem-loop structure that starts six nucleotides downstream from the proposed site of frameshifting, near the end of the first reading frame.	./cache/cord-334123-wb45ww7f.txt	./txt/cord-334123-wb45ww7f.txt