id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275349-b35pt3mo	Lenz, Heinz-Josef	The Emergence of Baricitinib: A Story of Tortoises Versus Hares	2020-07-06		.txt	text/plain	1403	63	37	The artificial intelligence algorithms predicted that baricitinib would inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of cells [2] , (an effect later confirmed in human liver spheroids) [3] , combined with its better-known anti-inflammatory properties. Consequently, the combined potential antiviral and anti-inflammatory effects of this dually acting drug could be ideal for halting the progression of the disease in hospitalized patients, when taken for a limited duration. This new paper in the journal extends the previous published reports of baricitinib treatment in mild-tomoderate COVID19 patients and provides further evidence that baricitinib could be a potential treatment for unwell hospitalized patients with this disease, independent of severity. One would be advised to remain vigilant of such signals reflecting thromboembolic or infection risk in randomized controlled trials testing a variety of immunomodulatory therapies in COVID-19 patients, either alone or in combination, especially in view of associations between clots and SARS-CoV-2 infection [10] .	./cache/cord-275349-b35pt3mo.txt	./txt/cord-275349-b35pt3mo.txt