id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-313499-8ijbesl8	Stowell, Sean	Role of serology in the COVID-19 pandemic	2020-05-01		.txt	text/plain	1211	61	39	In this issue of Clinical Infections Diseases, F Xiang et al present a serologic study of 85 nucleic acid test (NAT) SARS-CoV-2 positive patients and 24 NAT negative patients who had symptoms suspicious for COVID-19 1 . Serological testing consisted of an enzyme linked immunosorbent assay designed to detect IgM and IgG antibodies against the N protein of SARS-CoV-2. In patients with suspected COVID-19 who tested NAT negative, IgM antibodies were detected in 87.5% and IgG was present in 70.8%. In the case of COVID-19, while serological analysis may be helpful in examining exposure, such approaches can be more challenging to interpret in patients with acute infection. Despite these considerations, the results of this manuscript suggest repeat serological testing may be informative in the acute setting, especially in patients who continue to follow a COVID-19-like disease course despite NAT negativity. Additional testing, such as NAT testing, may be warranted in serological positive individuals to determine potential risk for infecting others.	./cache/cord-313499-8ijbesl8.txt	./txt/cord-313499-8ijbesl8.txt