id author title date pages extension mime words sentences flesch summary cache txt cord-263568-ea3k2i69 Price, Elizabeth Could the severity of COVID-19 be increased by low gastric acidity? 2020-07-22 .txt text/plain 765 45 55 title: Could the severity of COVID-19 be increased by low gastric acidity? Could the severity of COVID-19 be increased by low gastric acidity? Could low gastric acidity increase the risk of a severe COVID-19 illness? Although it is primarily a respiratory infection, gastrointestinal involvement from swallowed coronaviruses is reported for SARS-CoV-2 (the virus of COVID-19 [1, 2] ), as well as SARS-CoV-1 [3] and MERS-CoV viruses [4] . As well as protection related to immunological factors and possible differences in the ACE2 receptor concentrations in their lungs, children (other than infants) generally have good levels of gastric acid. To determine whether gastric acid gives some protection from COVID-19, the amount of antacids and acid-reducing drugs used by patients with severe infections could be compared with the amount used by patients with mild or no disease. If there is evidence for some protection by gastric acidity, stopping antacids and acid-reducing medications could be considered, particularly at times when patients are at increased risk. ./cache/cord-263568-ea3k2i69.txt ./txt/cord-263568-ea3k2i69.txt