id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-267348-bkirv9pt	Sakano, Takashi	Above and beyond: biofilm and the ongoing search for strategies to reduce ventilator-associated pneumonia (VAP)	2020-08-18		.txt	text/plain	576	46	44	title: Above and beyond: biofilm and the ongoing search for strategies to reduce ventilator-associated pneumonia (VAP) [1] that compared biofilm formation on three endotracheal tube (ETT) types with the finding that biofilm formation was reduced in silicone and noble-metal coated ETTs compared to uncoated ETTs. Their findings have significant implications during the current pandemic given the prolonged intubation times of COVID-19 patients and many develop superimposed pneumonias during their hospital course. It is intriguing that simply changing the ETT's coating may have significant implications in this patient population with already limited pulmonary reserve that is unable to tolerate additional insults to their lung from a ventilator-associated pneumonia (VAP). However, given the prolonged intubation times of COVID-19 patients, it is likely that the ETT biofilm burden will be substantial no matter which surface coating is utilized. It is widely accepted that two mechanisms lead to VAP: aspiration of oral-gastric contents and microbial biofilm development on the ETT.	./cache/cord-267348-bkirv9pt.txt	./txt/cord-267348-bkirv9pt.txt