id author title date pages extension mime words sentences flesch summary cache txt cord-325626-r7k7u7ro Yu, Xia SARS-CoV-2 viral load in sputum correlates with risk of COVID-19 progression 2020-04-23 .txt text/plain 796 60 55 In the study, we retrospectively collected the virological data, as well as demographic, epidemiological clinical information of 92 patients with confirmed COVID-19 in a single hospital in Zhejiang Province, China. We compared the baseline viral loads between severe patients and those mild to moderate at admission and also between those developing severe disease during hospitalization and those not. We studied 92 patients with confirmed COVID-19 who were admitted from January 19, 2020, to March 19, 2020, in the First Affiliated Hospital of Zhejiang University. The sputum specimens were collected from the lower respiratory tract of each patient at admission and the levels of viral nuclei acid were determined by a real-time PCR (RT-PCR) approach and indicated by the cycle threshold (Ct) values of RT-PCR assays [2] . We found that the viral load of the sputum specimen in the lower respiratory tract tested at baseline is closely related to the severity of COVID-19. ./cache/cord-325626-r7k7u7ro.txt ./txt/cord-325626-r7k7u7ro.txt