id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-326124-jtpsydy5	Adam, Elisabeth H.	Fibrin-derived peptide Bβ15-42 (FX06) as salvage treatment in critically ill patients with COVID-19-associated acute respiratory distress syndrome	2020-09-24		.txt	text/plain	883	58	46	title: Fibrin-derived peptide Bβ15-42 (FX06) as salvage treatment in critically ill patients with COVID-19-associated acute respiratory distress syndrome Here, we describe the empirical salvage treatment of critically ill COVID-19 patients in two German tertiary care University Hospitals with FX06 (F4 Pharma, Vienna, Austria), a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bβ15-42). This observational case series includes six patients during their treatment in the intensive care unit. Based on our experience, the salvage use of FX06 in severe COVID-19-associated ARDS could be an effective therapy to improve pulmonary function and vascular leakage in the most severely ill patients. FX06 (fibrin-derived peptide Bbeta15-42)-a potential candidate for myocardial reperfusion therapy EA, BS, and PM analyzed and interpreted the patient data and wrote the manuscript. This study was funded by institutional funds of both University hospitals. The study was approved by the local ethics committee (University Hospital Frankfurt, Frankfurt, Germany) (#20-643).	./cache/cord-326124-jtpsydy5.txt	./txt/cord-326124-jtpsydy5.txt