id sid tid token lemma pos cord-010055-exi8t6jt 1 1 key key JJ cord-010055-exi8t6jt 1 2 : : : cord-010055-exi8t6jt 1 3 cord-010055-exi8t6jt cord-010055-exi8t6jt CD cord-010055-exi8t6jt 1 4 authors author NNS cord-010055-exi8t6jt 1 5 : : : cord-010055-exi8t6jt 1 6 Zhu Zhu NNP cord-010055-exi8t6jt 1 7 , , , cord-010055-exi8t6jt 1 8 Guang Guang NNP cord-010055-exi8t6jt 1 9 - - HYPH cord-010055-exi8t6jt 1 10 wen wen NNP cord-010055-exi8t6jt 1 11 ; ; : cord-010055-exi8t6jt 1 12 Gao Gao NNP cord-010055-exi8t6jt 1 13 , , , cord-010055-exi8t6jt 1 14 Zhou Zhou NNP cord-010055-exi8t6jt 1 15 ; ; : cord-010055-exi8t6jt 1 16 Rachid Rachid NNP cord-010055-exi8t6jt 1 17 , , , cord-010055-exi8t6jt 1 18 Abdoul Abdoul NNP cord-010055-exi8t6jt 1 19 ; ; : cord-010055-exi8t6jt 1 20 Liu Liu NNP cord-010055-exi8t6jt 1 21 , , , cord-010055-exi8t6jt 2 1 Hui Hui NNP cord-010055-exi8t6jt 2 2 title title NN cord-010055-exi8t6jt 2 3 : : : cord-010055-exi8t6jt 2 4 Whether whether IN cord-010055-exi8t6jt 2 5 the the DT cord-010055-exi8t6jt 2 6 GFR GFR NNP cord-010055-exi8t6jt 2 7 measured measure VBN cord-010055-exi8t6jt 2 8 by by IN cord-010055-exi8t6jt 2 9 renal renal JJ cord-010055-exi8t6jt 2 10 scintigraphy scintigraphy NN cord-010055-exi8t6jt 2 11 under under IN cord-010055-exi8t6jt 2 12 non non JJ cord-010055-exi8t6jt 2 13 - - JJ cord-010055-exi8t6jt 2 14 steady steady JJ cord-010055-exi8t6jt 2 15 state state NN cord-010055-exi8t6jt 2 16 conditions condition NNS cord-010055-exi8t6jt 2 17 for for IN cord-010055-exi8t6jt 2 18 critically critically RB cord-010055-exi8t6jt 2 19 ill ill JJ cord-010055-exi8t6jt 2 20 patients patient NNS cord-010055-exi8t6jt 2 21 with with IN cord-010055-exi8t6jt 2 22 AKI AKI NNP cord-010055-exi8t6jt 2 23 can can MD cord-010055-exi8t6jt 2 24 be be VB cord-010055-exi8t6jt 2 25 used use VBN cord-010055-exi8t6jt 2 26 as as IN cord-010055-exi8t6jt 2 27 a a DT cord-010055-exi8t6jt 2 28 predictive predictive JJ cord-010055-exi8t6jt 2 29 parameter parameter NN cord-010055-exi8t6jt 2 30 for for IN cord-010055-exi8t6jt 2 31 clinical clinical JJ cord-010055-exi8t6jt 2 32 events event NNS cord-010055-exi8t6jt 2 33 date date NN cord-010055-exi8t6jt 2 34 : : : cord-010055-exi8t6jt 2 35 2020 2020 CD cord-010055-exi8t6jt 2 36 - - HYPH cord-010055-exi8t6jt 2 37 04 04 CD cord-010055-exi8t6jt 2 38 - - HYPH cord-010055-exi8t6jt 2 39 19 19 CD cord-010055-exi8t6jt 2 40 journal journal NN cord-010055-exi8t6jt 2 41 : : : cord-010055-exi8t6jt 3 1 Crit Crit NNP cord-010055-exi8t6jt 3 2 Care Care NNP cord-010055-exi8t6jt 3 3 DOI doi NN cord-010055-exi8t6jt 3 4 : : : cord-010055-exi8t6jt 3 5 10.1186 10.1186 CD cord-010055-exi8t6jt 3 6 / / SYM cord-010055-exi8t6jt 3 7 s13054 s13054 NN cord-010055-exi8t6jt 3 8 - - HYPH cord-010055-exi8t6jt 3 9 020 020 CD cord-010055-exi8t6jt 3 10 - - HYPH cord-010055-exi8t6jt 3 11 02850 02850 CD cord-010055-exi8t6jt 3 12 - - SYM cord-010055-exi8t6jt 3 13 5 5 CD cord-010055-exi8t6jt 4 1 sha sha NNP cord-010055-exi8t6jt 4 2 : : : cord-010055-exi8t6jt 5 1 6aed34afb60a8ad8ed2db4be87ed586c467b4741 6aed34afb60a8ad8ed2db4be87ed586c467b4741 CD cord-010055-exi8t6jt 5 2 doc_id doc_id CD cord-010055-exi8t6jt 5 3 : : : cord-010055-exi8t6jt 5 4 10055 10055 CD cord-010055-exi8t6jt 5 5 cord_uid cord_uid NNS cord-010055-exi8t6jt 5 6 : : : cord-010055-exi8t6jt 6 1 exi8t6jt exi8t6jt NNP cord-010055-exi8t6jt 6 2 nan nan NNP cord-010055-exi8t6jt 7 1 Whether whether IN cord-010055-exi8t6jt 7 2 the the DT cord-010055-exi8t6jt 7 3 GFR GFR NNP cord-010055-exi8t6jt 7 4 measured measure VBN cord-010055-exi8t6jt 7 5 by by IN cord-010055-exi8t6jt 7 6 renal renal JJ cord-010055-exi8t6jt 7 7 scintigraphy scintigraphy NN cord-010055-exi8t6jt 7 8 under under IN cord-010055-exi8t6jt 7 9 non non JJ cord-010055-exi8t6jt 7 10 - - JJ cord-010055-exi8t6jt 7 11 steady steady JJ cord-010055-exi8t6jt 7 12 state state NN cord-010055-exi8t6jt 7 13 conditions condition NNS cord-010055-exi8t6jt 7 14 for for IN cord-010055-exi8t6jt 7 15 critically critically RB cord-010055-exi8t6jt 7 16 ill ill JJ cord-010055-exi8t6jt 7 17 patients patient NNS cord-010055-exi8t6jt 7 18 with with IN cord-010055-exi8t6jt 7 19 AKI AKI NNP cord-010055-exi8t6jt 7 20 can can MD cord-010055-exi8t6jt 7 21 be be VB cord-010055-exi8t6jt 7 22 used use VBN cord-010055-exi8t6jt 7 23 as as IN cord-010055-exi8t6jt 7 24 a a DT cord-010055-exi8t6jt 7 25 predictive predictive JJ cord-010055-exi8t6jt 7 26 parameter parameter NN cord-010055-exi8t6jt 7 27 for for IN cord-010055-exi8t6jt 7 28 clinical clinical JJ cord-010055-exi8t6jt 7 29 events event NNS cord-010055-exi8t6jt 7 30 Guang Guang NNP cord-010055-exi8t6jt 7 31 - - HYPH cord-010055-exi8t6jt 7 32 wen wen NNP cord-010055-exi8t6jt 7 33 Zhu Zhu NNP cord-010055-exi8t6jt 7 34 1 1 CD cord-010055-exi8t6jt 8 1 * * NFP cord-010055-exi8t6jt 8 2 , , , cord-010055-exi8t6jt 8 3 Zhou Zhou NNP cord-010055-exi8t6jt 8 4 Gao Gao NNP cord-010055-exi8t6jt 8 5 2 2 CD cord-010055-exi8t6jt 8 6 , , , cord-010055-exi8t6jt 8 7 Abdoul Abdoul NNP cord-010055-exi8t6jt 8 8 Rachid Rachid NNP cord-010055-exi8t6jt 9 1 3 3 CD cord-010055-exi8t6jt 9 2 _SP cord-010055-exi8t6jt 10 1 Whether whether IN cord-010055-exi8t6jt 10 2 the the DT cord-010055-exi8t6jt 10 3 GFR GFR NNP cord-010055-exi8t6jt 10 4 measured measure VBN cord-010055-exi8t6jt 10 5 by by IN cord-010055-exi8t6jt 10 6 renal renal JJ cord-010055-exi8t6jt 10 7 scintigraphy scintigraphy NN cord-010055-exi8t6jt 10 8 under under IN cord-010055-exi8t6jt 10 9 non non JJ cord-010055-exi8t6jt 10 10 - - JJ cord-010055-exi8t6jt 10 11 steady steady JJ cord-010055-exi8t6jt 10 12 state state NN cord-010055-exi8t6jt 10 13 conditions condition NNS cord-010055-exi8t6jt 10 14 for for IN cord-010055-exi8t6jt 10 15 critically critically RB cord-010055-exi8t6jt 10 16 ill ill JJ cord-010055-exi8t6jt 10 17 patients patient NNS cord-010055-exi8t6jt 10 18 with with IN cord-010055-exi8t6jt 10 19 AKI AKI NNP cord-010055-exi8t6jt 10 20 can can MD cord-010055-exi8t6jt 10 21 be be VB cord-010055-exi8t6jt 10 22 used use VBN cord-010055-exi8t6jt 10 23 as as IN cord-010055-exi8t6jt 10 24 a a DT cord-010055-exi8t6jt 10 25 predictive predictive JJ cord-010055-exi8t6jt 10 26 parameter parameter NN cord-010055-exi8t6jt 10 27 for for IN cord-010055-exi8t6jt 10 28 clinical clinical JJ cord-010055-exi8t6jt 10 29 events event NNS cord-010055-exi8t6jt 11 1 Dear Dear NNP cord-010055-exi8t6jt 11 2 Editor Editor NNP cord-010055-exi8t6jt 11 3 : : : cord-010055-exi8t6jt 11 4 We -PRON- PRP cord-010055-exi8t6jt 11 5 read read VBP cord-010055-exi8t6jt 11 6 with with IN cord-010055-exi8t6jt 11 7 great great JJ cord-010055-exi8t6jt 11 8 attention attention NN cord-010055-exi8t6jt 11 9 and and CC cord-010055-exi8t6jt 11 10 interest interest NN cord-010055-exi8t6jt 11 11 the the DT cord-010055-exi8t6jt 11 12 paper paper NN cord-010055-exi8t6jt 11 13 by by IN cord-010055-exi8t6jt 11 14 Katulka Katulka NNP cord-010055-exi8t6jt 11 15 et et NNP cord-010055-exi8t6jt 11 16 al al NNP cord-010055-exi8t6jt 11 17 . . . cord-010055-exi8t6jt 12 1 about about IN cord-010055-exi8t6jt 12 2 the the DT cord-010055-exi8t6jt 12 3 current current JJ cord-010055-exi8t6jt 12 4 evidence evidence NN cord-010055-exi8t6jt 12 5 for for IN cord-010055-exi8t6jt 12 6 clinical clinical JJ cord-010055-exi8t6jt 12 7 and and CC cord-010055-exi8t6jt 12 8 biochemical biochemical JJ cord-010055-exi8t6jt 12 9 parameters parameter NNS cord-010055-exi8t6jt 12 10 for for IN cord-010055-exi8t6jt 12 11 predicting predict VBG cord-010055-exi8t6jt 12 12 successful successful JJ cord-010055-exi8t6jt 12 13 discontinuation discontinuation NN cord-010055-exi8t6jt 12 14 of of IN cord-010055-exi8t6jt 12 15 RRT rrt NN cord-010055-exi8t6jt 12 16 [ [ -LRB- cord-010055-exi8t6jt 12 17 1 1 CD cord-010055-exi8t6jt 12 18 ] ] -RRB- cord-010055-exi8t6jt 12 19 . . . cord-010055-exi8t6jt 13 1 We -PRON- PRP cord-010055-exi8t6jt 13 2 would would MD cord-010055-exi8t6jt 13 3 like like VB cord-010055-exi8t6jt 13 4 to to TO cord-010055-exi8t6jt 13 5 add add VB cord-010055-exi8t6jt 13 6 some some DT cord-010055-exi8t6jt 13 7 comments comment NNS cord-010055-exi8t6jt 13 8 in in IN cord-010055-exi8t6jt 13 9 regard regard NN cord-010055-exi8t6jt 13 10 to to IN cord-010055-exi8t6jt 13 11 their -PRON- PRP$ cord-010055-exi8t6jt 13 12 conclusion conclusion NN cord-010055-exi8t6jt 13 13 that that IN cord-010055-exi8t6jt 13 14 multiple multiple JJ cord-010055-exi8t6jt 13 15 studies study NNS cord-010055-exi8t6jt 13 16 reported report VBN cord-010055-exi8t6jt 13 17 on on IN cord-010055-exi8t6jt 13 18 the the DT cord-010055-exi8t6jt 13 19 same same JJ cord-010055-exi8t6jt 13 20 parameter parameter NN cord-010055-exi8t6jt 13 21 ( ( -LRB- cord-010055-exi8t6jt 13 22 urine urine NN cord-010055-exi8t6jt 13 23 output output NN cord-010055-exi8t6jt 13 24 , , , cord-010055-exi8t6jt 13 25 diuretic diuretic JJ cord-010055-exi8t6jt 13 26 test test NN cord-010055-exi8t6jt 13 27 , , , cord-010055-exi8t6jt 13 28 CrCl CrCl NNP cord-010055-exi8t6jt 13 29 , , , cord-010055-exi8t6jt 13 30 cystatin cystatin NNP cord-010055-exi8t6jt 13 31 C C NNP cord-010055-exi8t6jt 13 32 , , , cord-010055-exi8t6jt 13 33 NGAL NGAL NNP cord-010055-exi8t6jt 13 34 , , , cord-010055-exi8t6jt 13 35 eGFR egfr NN cord-010055-exi8t6jt 13 36 , , , cord-010055-exi8t6jt 13 37 KeGFR KeGFR NNP cord-010055-exi8t6jt 13 38 ) ) -RRB- cord-010055-exi8t6jt 13 39 , , , cord-010055-exi8t6jt 13 40 but but CC cord-010055-exi8t6jt 13 41 an an DT cord-010055-exi8t6jt 13 42 optimal optimal JJ cord-010055-exi8t6jt 13 43 threshold threshold NN cord-010055-exi8t6jt 13 44 value value NN cord-010055-exi8t6jt 13 45 was be VBD cord-010055-exi8t6jt 13 46 not not RB cord-010055-exi8t6jt 13 47 determined determine VBN cord-010055-exi8t6jt 13 48 due due JJ cord-010055-exi8t6jt 13 49 also also RB cord-010055-exi8t6jt 13 50 to to IN cord-010055-exi8t6jt 13 51 heterogeneity heterogeneity NN cord-010055-exi8t6jt 13 52 . . . cord-010055-exi8t6jt 14 1 For for IN cord-010055-exi8t6jt 14 2 GFR GFR NNP cord-010055-exi8t6jt 14 3 measurement measurement NN cord-010055-exi8t6jt 14 4 , , , cord-010055-exi8t6jt 14 5 we -PRON- PRP cord-010055-exi8t6jt 14 6 believe believe VBP cord-010055-exi8t6jt 14 7 that that IN cord-010055-exi8t6jt 14 8 based base VBN cord-010055-exi8t6jt 14 9 on on IN cord-010055-exi8t6jt 14 10 the the DT cord-010055-exi8t6jt 14 11 principle principle NN cord-010055-exi8t6jt 14 12 of of IN cord-010055-exi8t6jt 14 13 radionuclide radionuclide NN cord-010055-exi8t6jt 14 14 - - HYPH cord-010055-exi8t6jt 14 15 based base VBN cord-010055-exi8t6jt 14 16 techniques technique NNS cord-010055-exi8t6jt 14 17 and and CC cord-010055-exi8t6jt 14 18 its -PRON- PRP$ cord-010055-exi8t6jt 14 19 advantages advantage NNS cord-010055-exi8t6jt 14 20 of of IN cord-010055-exi8t6jt 14 21 repeatability repeatability NN cord-010055-exi8t6jt 14 22 of of IN cord-010055-exi8t6jt 14 23 results result NNS cord-010055-exi8t6jt 14 24 , , , cord-010055-exi8t6jt 14 25 the the DT cord-010055-exi8t6jt 14 26 heterogeneity heterogeneity NN cord-010055-exi8t6jt 14 27 of of IN cord-010055-exi8t6jt 14 28 those those DT cord-010055-exi8t6jt 14 29 above above IN cord-010055-exi8t6jt 14 30 results result NNS cord-010055-exi8t6jt 14 31 may may MD cord-010055-exi8t6jt 14 32 be be VB cord-010055-exi8t6jt 14 33 avoided avoid VBN cord-010055-exi8t6jt 14 34 . . . cord-010055-exi8t6jt 15 1 99mTc 99mtc LS cord-010055-exi8t6jt 15 2 - - : cord-010055-exi8t6jt 15 3 DTPA DTPA NNP cord-010055-exi8t6jt 15 4 has have VBZ cord-010055-exi8t6jt 15 5 become become VBN cord-010055-exi8t6jt 15 6 a a DT cord-010055-exi8t6jt 15 7 standard standard JJ cord-010055-exi8t6jt 15 8 GFR GFR NNP cord-010055-exi8t6jt 15 9 tracer tracer NN cord-010055-exi8t6jt 15 10 , , , cord-010055-exi8t6jt 15 11 the the DT cord-010055-exi8t6jt 15 12 hierarchy hierarchy NN cord-010055-exi8t6jt 15 13 of of IN cord-010055-exi8t6jt 15 14 99mTc 99mtc JJ cord-010055-exi8t6jt 15 15 - - HYPH cord-010055-exi8t6jt 15 16 DTPA dtpa NN cord-010055-exi8t6jt 15 17 renal renal JJ cord-010055-exi8t6jt 15 18 imaging imaging NN cord-010055-exi8t6jt 15 19 is be VBZ cord-010055-exi8t6jt 15 20 considered consider VBN cord-010055-exi8t6jt 15 21 to to TO cord-010055-exi8t6jt 15 22 be be VB cord-010055-exi8t6jt 15 23 the the DT cord-010055-exi8t6jt 15 24 silver silver JJ cord-010055-exi8t6jt 15 25 standard standard NN cord-010055-exi8t6jt 15 26 among among IN cord-010055-exi8t6jt 15 27 all all DT cord-010055-exi8t6jt 15 28 used use VBN cord-010055-exi8t6jt 15 29 approaches approach NNS cord-010055-exi8t6jt 15 30 for for IN cord-010055-exi8t6jt 15 31 detecting detect VBG cord-010055-exi8t6jt 15 32 GFR GFR NNP cord-010055-exi8t6jt 15 33 [ [ -LRB- cord-010055-exi8t6jt 15 34 2 2 CD cord-010055-exi8t6jt 15 35 ] ] -RRB- cord-010055-exi8t6jt 15 36 , , , cord-010055-exi8t6jt 15 37 including include VBG cord-010055-exi8t6jt 15 38 Gates Gates NNP cord-010055-exi8t6jt 15 39 method method NN cord-010055-exi8t6jt 15 40 , , , cord-010055-exi8t6jt 15 41 modified modify VBN cord-010055-exi8t6jt 15 42 Gates Gates NNP cord-010055-exi8t6jt 15 43 method method NN cord-010055-exi8t6jt 15 44 , , , cord-010055-exi8t6jt 15 45 and and CC cord-010055-exi8t6jt 15 46 plasma plasma NN cord-010055-exi8t6jt 15 47 sample sample NN cord-010055-exi8t6jt 15 48 clearance clearance NN cord-010055-exi8t6jt 15 49 method method NN cord-010055-exi8t6jt 15 50 . . . cord-010055-exi8t6jt 16 1 Especially especially RB cord-010055-exi8t6jt 16 2 for for IN cord-010055-exi8t6jt 16 3 GFR GFR NNP cord-010055-exi8t6jt 16 4 measurement measurement NN cord-010055-exi8t6jt 16 5 in in IN cord-010055-exi8t6jt 16 6 AKI AKI NNP cord-010055-exi8t6jt 16 7 patients patient NNS cord-010055-exi8t6jt 16 8 , , , cord-010055-exi8t6jt 16 9 the the DT cord-010055-exi8t6jt 16 10 result result NN cord-010055-exi8t6jt 16 11 of of IN cord-010055-exi8t6jt 16 12 renal renal JJ cord-010055-exi8t6jt 16 13 scintigraphy scintigraphy NN cord-010055-exi8t6jt 16 14 may may MD cord-010055-exi8t6jt 16 15 be be VB cord-010055-exi8t6jt 16 16 more more RBR cord-010055-exi8t6jt 16 17 reliable reliable JJ cord-010055-exi8t6jt 16 18 than than IN cord-010055-exi8t6jt 16 19 other other JJ cord-010055-exi8t6jt 16 20 existing exist VBG cord-010055-exi8t6jt 16 21 technologies technology NNS cord-010055-exi8t6jt 16 22 and and CC cord-010055-exi8t6jt 16 23 is be VBZ cord-010055-exi8t6jt 16 24 not not RB cord-010055-exi8t6jt 16 25 affected affect VBN cord-010055-exi8t6jt 16 26 by by IN cord-010055-exi8t6jt 16 27 plasma plasma NN cord-010055-exi8t6jt 16 28 creatinine creatinine NN cord-010055-exi8t6jt 16 29 changing change VBG cord-010055-exi8t6jt 16 30 rapidly rapidly RB cord-010055-exi8t6jt 16 31 , , , cord-010055-exi8t6jt 16 32 fluid fluid JJ cord-010055-exi8t6jt 16 33 loading loading NN cord-010055-exi8t6jt 16 34 in in IN cord-010055-exi8t6jt 16 35 ICU ICU NNP cord-010055-exi8t6jt 16 36 , , , cord-010055-exi8t6jt 16 37 and and CC cord-010055-exi8t6jt 16 38 receiving receive VBG cord-010055-exi8t6jt 16 39 CRRT CRRT NNP cord-010055-exi8t6jt 16 40 . . . cord-010055-exi8t6jt 17 1 To to TO cord-010055-exi8t6jt 17 2 analyze analyze VB cord-010055-exi8t6jt 17 3 kidney kidney NN cord-010055-exi8t6jt 17 4 function function NN cord-010055-exi8t6jt 17 5 in in IN cord-010055-exi8t6jt 17 6 the the DT cord-010055-exi8t6jt 17 7 acute acute JJ cord-010055-exi8t6jt 17 8 setting setting NN cord-010055-exi8t6jt 17 9 , , , cord-010055-exi8t6jt 17 10 recently recently RB cord-010055-exi8t6jt 17 11 , , , cord-010055-exi8t6jt 17 12 our -PRON- PRP$ cord-010055-exi8t6jt 17 13 team team NN cord-010055-exi8t6jt 17 14 completed complete VBD cord-010055-exi8t6jt 17 15 a a DT cord-010055-exi8t6jt 17 16 special special JJ cord-010055-exi8t6jt 17 17 renal renal JJ cord-010055-exi8t6jt 17 18 scintigraphy scintigraphy NN cord-010055-exi8t6jt 17 19 for for IN cord-010055-exi8t6jt 17 20 a a DT cord-010055-exi8t6jt 17 21 critically critically RB cord-010055-exi8t6jt 17 22 ill ill JJ cord-010055-exi8t6jt 17 23 patient patient NN cord-010055-exi8t6jt 17 24 with with IN cord-010055-exi8t6jt 17 25 the the DT cord-010055-exi8t6jt 17 26 only only JJ cord-010055-exi8t6jt 17 27 venous venous JJ cord-010055-exi8t6jt 17 28 access access NN cord-010055-exi8t6jt 17 29 site site NN cord-010055-exi8t6jt 17 30 - - : cord-010055-exi8t6jt 17 31 PICC PICC NNP cord-010055-exi8t6jt 17 32 . . . cord-010055-exi8t6jt 18 1 A a DT cord-010055-exi8t6jt 18 2 renal renal JJ cord-010055-exi8t6jt 18 3 scintigraphy scintigraphy NN cord-010055-exi8t6jt 18 4 of of IN cord-010055-exi8t6jt 18 5 99mTc 99mtc XX cord-010055-exi8t6jt 18 6 - - HYPH cord-010055-exi8t6jt 18 7 DTPA DTPA NNP cord-010055-exi8t6jt 18 8 was be VBD cord-010055-exi8t6jt 18 9 performed perform VBN cord-010055-exi8t6jt 18 10 for for IN cord-010055-exi8t6jt 18 11 this this DT cord-010055-exi8t6jt 18 12 critical critical JJ cord-010055-exi8t6jt 18 13 patient patient NN cord-010055-exi8t6jt 18 14 with with IN cord-010055-exi8t6jt 18 15 AKI AKI NNP cord-010055-exi8t6jt 18 16 and and CC cord-010055-exi8t6jt 18 17 artificially artificially RB cord-010055-exi8t6jt 18 18 assisted assist VBD cord-010055-exi8t6jt 18 19 ventilation ventilation NN cord-010055-exi8t6jt 18 20 . . . cord-010055-exi8t6jt 19 1 The the DT cord-010055-exi8t6jt 19 2 normalized normalized JJ cord-010055-exi8t6jt 19 3 GFR GFR NNP cord-010055-exi8t6jt 19 4 was be VBD cord-010055-exi8t6jt 19 5 36.5 36.5 CD cord-010055-exi8t6jt 19 6 mL ml NN cord-010055-exi8t6jt 19 7 / / SYM cord-010055-exi8t6jt 19 8 min min NN cord-010055-exi8t6jt 20 1 ( ( -LRB- cord-010055-exi8t6jt 20 2 Fig Fig NNP cord-010055-exi8t6jt 20 3 . . NNP cord-010055-exi8t6jt 20 4 1 1 CD cord-010055-exi8t6jt 20 5 ) ) -RRB- cord-010055-exi8t6jt 20 6 . . . cord-010055-exi8t6jt 21 1 In in IN cord-010055-exi8t6jt 21 2 the the DT cord-010055-exi8t6jt 21 3 absence absence NN cord-010055-exi8t6jt 21 4 of of IN cord-010055-exi8t6jt 21 5 broad broad JJ cord-010055-exi8t6jt 21 6 guidelines guideline NNS cord-010055-exi8t6jt 21 7 [ [ -LRB- cord-010055-exi8t6jt 21 8 3 3 CD cord-010055-exi8t6jt 21 9 ] ] -RRB- cord-010055-exi8t6jt 21 10 , , , cord-010055-exi8t6jt 21 11 our -PRON- PRP$ cord-010055-exi8t6jt 21 12 team team NN cord-010055-exi8t6jt 21 13 proposed propose VBD cord-010055-exi8t6jt 21 14 the the DT cord-010055-exi8t6jt 21 15 following follow VBG cord-010055-exi8t6jt 21 16 procedure procedure NN cord-010055-exi8t6jt 21 17 / / SYM cord-010055-exi8t6jt 21 18 practice practice NN cord-010055-exi8t6jt 21 19 for for IN cord-010055-exi8t6jt 21 20 renal renal JJ cord-010055-exi8t6jt 21 21 scintigraphy scintigraphy NN cord-010055-exi8t6jt 21 22 by by IN cord-010055-exi8t6jt 21 23 PICC PICC NNP cord-010055-exi8t6jt 21 24 / / SYM cord-010055-exi8t6jt 21 25 CVC CVC NNP cord-010055-exi8t6jt 21 26 . . . cord-010055-exi8t6jt 22 1 After after IN cord-010055-exi8t6jt 22 2 intravenous intravenous JJ cord-010055-exi8t6jt 22 3 hydration hydration NN cord-010055-exi8t6jt 22 4 with with IN cord-010055-exi8t6jt 22 5 300 300 CD cord-010055-exi8t6jt 22 6 - - SYM cord-010055-exi8t6jt 22 7 500 500 CD cord-010055-exi8t6jt 22 8 mL ml NN cord-010055-exi8t6jt 22 9 of of IN cord-010055-exi8t6jt 22 10 fluid fluid NN cord-010055-exi8t6jt 22 11 ( ( -LRB- cord-010055-exi8t6jt 22 12 dextrose dextrose NN cord-010055-exi8t6jt 22 13 ; ; : cord-010055-exi8t6jt 22 14 5 5 CD cord-010055-exi8t6jt 22 15 % % NN cord-010055-exi8t6jt 22 16 glucose glucose NN cord-010055-exi8t6jt 22 17 or or CC cord-010055-exi8t6jt 22 18 0.9 0.9 CD cord-010055-exi8t6jt 22 19 % % NN cord-010055-exi8t6jt 22 20 sodium sodium NN cord-010055-exi8t6jt 22 21 chloride chloride NN cord-010055-exi8t6jt 22 22 ) ) -RRB- cord-010055-exi8t6jt 23 1 30 30 CD cord-010055-exi8t6jt 23 2 min min NN cord-010055-exi8t6jt 23 3 , , , cord-010055-exi8t6jt 23 4 the the DT cord-010055-exi8t6jt 23 5 patency patency NN cord-010055-exi8t6jt 23 6 of of IN cord-010055-exi8t6jt 23 7 the the DT cord-010055-exi8t6jt 23 8 catheter catheter NN cord-010055-exi8t6jt 23 9 in in IN cord-010055-exi8t6jt 23 10 the the DT cord-010055-exi8t6jt 23 11 PICC PICC NNP cord-010055-exi8t6jt 23 12 / / SYM cord-010055-exi8t6jt 23 13 CVC CVC NNP cord-010055-exi8t6jt 23 14 system system NN cord-010055-exi8t6jt 23 15 is be VBZ cord-010055-exi8t6jt 23 16 checked check VBN cord-010055-exi8t6jt 23 17 by by IN cord-010055-exi8t6jt 23 18 10 10 CD cord-010055-exi8t6jt 23 19 mL ml NN cord-010055-exi8t6jt 23 20 saline saline NN cord-010055-exi8t6jt 23 21 solution solution NN cord-010055-exi8t6jt 23 22 in in IN cord-010055-exi8t6jt 23 23 a a DT cord-010055-exi8t6jt 23 24 10-mL 10-ml CD cord-010055-exi8t6jt 23 25 syringe syringe NN cord-010055-exi8t6jt 23 26 . . . cord-010055-exi8t6jt 24 1 Then then RB cord-010055-exi8t6jt 24 2 , , , cord-010055-exi8t6jt 24 3 a a DT cord-010055-exi8t6jt 24 4 bolus bolus NN cord-010055-exi8t6jt 24 5 injection injection NN cord-010055-exi8t6jt 24 6 of of IN cord-010055-exi8t6jt 24 7 radiopharmaceutical radiopharmaceutical NN cord-010055-exi8t6jt 24 8 via via IN cord-010055-exi8t6jt 24 9 PICC PICC NNP cord-010055-exi8t6jt 24 10 or or CC cord-010055-exi8t6jt 24 11 CVC CVC NNP cord-010055-exi8t6jt 24 12 is be VBZ cord-010055-exi8t6jt 24 13 done do VBN cord-010055-exi8t6jt 24 14 , , , cord-010055-exi8t6jt 24 15 immediately immediately RB cord-010055-exi8t6jt 24 16 following follow VBG cord-010055-exi8t6jt 24 17 and and CC cord-010055-exi8t6jt 24 18 flushing flush VBG cord-010055-exi8t6jt 24 19 with with IN cord-010055-exi8t6jt 24 20 10 10 CD cord-010055-exi8t6jt 24 21 - - SYM cord-010055-exi8t6jt 24 22 20 20 CD cord-010055-exi8t6jt 24 23 mL ml NN cord-010055-exi8t6jt 24 24 normal normal JJ cord-010055-exi8t6jt 24 25 saline saline NN cord-010055-exi8t6jt 24 26 or or CC cord-010055-exi8t6jt 24 27 heparin heparin NN cord-010055-exi8t6jt 24 28 ( ( -LRB- cord-010055-exi8t6jt 24 29 100 100 CD cord-010055-exi8t6jt 24 30 U u NN cord-010055-exi8t6jt 24 31 ) ) -RRB- cord-010055-exi8t6jt 24 32 sodium sodium NN cord-010055-exi8t6jt 24 33 solution solution NN cord-010055-exi8t6jt 24 34 using use VBG cord-010055-exi8t6jt 24 35 the the DT cord-010055-exi8t6jt 24 36 " " `` cord-010055-exi8t6jt 24 37 push push VB cord-010055-exi8t6jt 24 38 - - HYPH cord-010055-exi8t6jt 24 39 pause pause NN cord-010055-exi8t6jt 24 40 " " '' cord-010055-exi8t6jt 24 41 technique technique NN cord-010055-exi8t6jt 24 42 for for IN cord-010055-exi8t6jt 24 43 the the DT cord-010055-exi8t6jt 24 44 lock lock NN cord-010055-exi8t6jt 24 45 of of IN cord-010055-exi8t6jt 24 46 the the DT cord-010055-exi8t6jt 24 47 system system NN cord-010055-exi8t6jt 24 48 depositing deposit VBG cord-010055-exi8t6jt 24 49 with with IN cord-010055-exi8t6jt 24 50 positive positive JJ cord-010055-exi8t6jt 24 51 pressure pressure NN cord-010055-exi8t6jt 24 52 [ [ -LRB- cord-010055-exi8t6jt 24 53 4 4 CD cord-010055-exi8t6jt 24 54 ] ] -RRB- cord-010055-exi8t6jt 24 55 , , , cord-010055-exi8t6jt 24 56 while while IN cord-010055-exi8t6jt 24 57 a a DT cord-010055-exi8t6jt 24 58 standard standard JJ cord-010055-exi8t6jt 24 59 20/30-min 20/30-min CD cord-010055-exi8t6jt 24 60 dynamic dynamic JJ cord-010055-exi8t6jt 24 61 renal renal JJ cord-010055-exi8t6jt 24 62 scintigraphy scintigraphy NN cord-010055-exi8t6jt 24 63 is be VBZ cord-010055-exi8t6jt 24 64 performed perform VBN cord-010055-exi8t6jt 24 65 . . . cord-010055-exi8t6jt 25 1 Although although IN cord-010055-exi8t6jt 25 2 renal renal JJ cord-010055-exi8t6jt 25 3 scintigraphy scintigraphy NN cord-010055-exi8t6jt 25 4 is be VBZ cord-010055-exi8t6jt 25 5 rarely rarely RB cord-010055-exi8t6jt 25 6 used use VBN cord-010055-exi8t6jt 25 7 clinically clinically RB cord-010055-exi8t6jt 25 8 for for IN cord-010055-exi8t6jt 25 9 critically critically RB cord-010055-exi8t6jt 25 10 ill ill JJ cord-010055-exi8t6jt 25 11 patients patient NNS cord-010055-exi8t6jt 25 12 with with IN cord-010055-exi8t6jt 25 13 AKI AKI NNP cord-010055-exi8t6jt 25 14 , , , cord-010055-exi8t6jt 25 15 partly partly RB cord-010055-exi8t6jt 25 16 because because IN cord-010055-exi8t6jt 25 17 of of IN cord-010055-exi8t6jt 25 18 a a DT cord-010055-exi8t6jt 25 19 lack lack NN cord-010055-exi8t6jt 25 20 of of IN cord-010055-exi8t6jt 25 21 understanding understanding NN cord-010055-exi8t6jt 25 22 of of IN cord-010055-exi8t6jt 25 23 the the DT cord-010055-exi8t6jt 25 24 technology technology NN cord-010055-exi8t6jt 25 25 , , , cord-010055-exi8t6jt 25 26 it -PRON- PRP cord-010055-exi8t6jt 25 27 can can MD cord-010055-exi8t6jt 25 28 actually actually RB cord-010055-exi8t6jt 25 29 provide provide VB cord-010055-exi8t6jt 25 30 unique unique JJ cord-010055-exi8t6jt 25 31 kidneys kidney NNS cord-010055-exi8t6jt 25 32 ' ' POS cord-010055-exi8t6jt 25 33 function function NN cord-010055-exi8t6jt 25 34 parameters parameter NNS cord-010055-exi8t6jt 25 35 , , , cord-010055-exi8t6jt 25 36 split split VBD cord-010055-exi8t6jt 25 37 renal renal JJ cord-010055-exi8t6jt 25 38 function function NN cord-010055-exi8t6jt 25 39 , , , cord-010055-exi8t6jt 25 40 and and CC cord-010055-exi8t6jt 25 41 GFRs gfr NNS cord-010055-exi8t6jt 25 42 . . . cord-010055-exi8t6jt 26 1 The the DT cord-010055-exi8t6jt 26 2 GFRs gfr NNS cord-010055-exi8t6jt 26 3 measured measure VBN cord-010055-exi8t6jt 26 4 by by IN cord-010055-exi8t6jt 26 5 renal renal JJ cord-010055-exi8t6jt 26 6 scintigraphy scintigraphy NN cord-010055-exi8t6jt 26 7 alone alone RB cord-010055-exi8t6jt 26 8 or or CC cord-010055-exi8t6jt 26 9 with with IN cord-010055-exi8t6jt 26 10 other other JJ cord-010055-exi8t6jt 26 11 static static JJ cord-010055-exi8t6jt 26 12 and and CC cord-010055-exi8t6jt 26 13 dynamic dynamic JJ cord-010055-exi8t6jt 26 14 clinical clinical JJ cord-010055-exi8t6jt 26 15 variables variable NNS cord-010055-exi8t6jt 26 16 may may MD cord-010055-exi8t6jt 26 17 have have VB cord-010055-exi8t6jt 26 18 a a DT cord-010055-exi8t6jt 26 19 predictive predictive JJ cord-010055-exi8t6jt 26 20 value value NN cord-010055-exi8t6jt 26 21 for for IN cord-010055-exi8t6jt 26 22 stratification stratification NN cord-010055-exi8t6jt 26 23 and and CC cord-010055-exi8t6jt 26 24 clinical clinical JJ cord-010055-exi8t6jt 26 25 events event NNS cord-010055-exi8t6jt 26 26 in in IN cord-010055-exi8t6jt 26 27 critically critically RB cord-010055-exi8t6jt 26 28 ill ill JJ cord-010055-exi8t6jt 26 29 patients patient NNS cord-010055-exi8t6jt 26 30 . . . cord-010055-exi8t6jt 27 1 Fig Fig NNP cord-010055-exi8t6jt 27 2 . . . cord-010055-exi8t6jt 28 1 1 1 CD cord-010055-exi8t6jt 28 2 Dynamic dynamic JJ cord-010055-exi8t6jt 28 3 renal renal JJ cord-010055-exi8t6jt 28 4 scintigraphy scintigraphy NN cord-010055-exi8t6jt 28 5 for for IN cord-010055-exi8t6jt 28 6 a a DT cord-010055-exi8t6jt 28 7 critical critical JJ cord-010055-exi8t6jt 28 8 patient patient NN cord-010055-exi8t6jt 28 9 by by IN cord-010055-exi8t6jt 28 10 PICC PICC NNP cord-010055-exi8t6jt 28 11 . . . cord-010055-exi8t6jt 29 1 A a DT cord-010055-exi8t6jt 29 2 65-year 65-year JJ cord-010055-exi8t6jt 29 3 - - HYPH cord-010055-exi8t6jt 29 4 old old JJ cord-010055-exi8t6jt 29 5 man man NN cord-010055-exi8t6jt 29 6 with with IN cord-010055-exi8t6jt 29 7 absence absence NN cord-010055-exi8t6jt 29 8 of of IN cord-010055-exi8t6jt 29 9 urine urine NN cord-010055-exi8t6jt 29 10 for for IN cord-010055-exi8t6jt 29 11 3 3 CD cord-010055-exi8t6jt 29 12 days day NNS cord-010055-exi8t6jt 29 13 ; ; : cord-010055-exi8t6jt 29 14 he -PRON- PRP cord-010055-exi8t6jt 29 15 was be VBD cord-010055-exi8t6jt 29 16 diagnosed diagnose VBN cord-010055-exi8t6jt 29 17 with with IN cord-010055-exi8t6jt 29 18 AKI AKI NNP cord-010055-exi8t6jt 29 19 stage stage NN cord-010055-exi8t6jt 29 20 3 3 CD cord-010055-exi8t6jt 29 21 , , , cord-010055-exi8t6jt 29 22 lung lung NN cord-010055-exi8t6jt 29 23 infection infection NN cord-010055-exi8t6jt 29 24 , , , cord-010055-exi8t6jt 29 25 atelectasis atelectasis NN cord-010055-exi8t6jt 29 26 , , , cord-010055-exi8t6jt 29 27 electrolyte electrolyte NN cord-010055-exi8t6jt 29 28 disorders disorder NNS cord-010055-exi8t6jt 29 29 , , , cord-010055-exi8t6jt 29 30 and and CC cord-010055-exi8t6jt 29 31 coagulopathy coagulopathy NN cord-010055-exi8t6jt 29 32 , , , cord-010055-exi8t6jt 29 33 and and CC cord-010055-exi8t6jt 29 34 the the DT cord-010055-exi8t6jt 29 35 CRRT CRRT NNP cord-010055-exi8t6jt 29 36 was be VBD cord-010055-exi8t6jt 29 37 initiated initiate VBN cord-010055-exi8t6jt 29 38 . . . cord-010055-exi8t6jt 30 1 On on IN cord-010055-exi8t6jt 30 2 the the DT cord-010055-exi8t6jt 30 3 fifth fifth JJ cord-010055-exi8t6jt 30 4 day day NN cord-010055-exi8t6jt 30 5 , , , cord-010055-exi8t6jt 30 6 the the DT cord-010055-exi8t6jt 30 7 patient patient NN cord-010055-exi8t6jt 30 8 was be VBD cord-010055-exi8t6jt 30 9 performed perform VBN cord-010055-exi8t6jt 30 10 with with IN cord-010055-exi8t6jt 30 11 endotracheal endotracheal JJ cord-010055-exi8t6jt 30 12 intubation intubation NN cord-010055-exi8t6jt 30 13 and and CC cord-010055-exi8t6jt 30 14 ventilator ventilator NN cord-010055-exi8t6jt 30 15 - - HYPH cord-010055-exi8t6jt 30 16 assisted assist VBN cord-010055-exi8t6jt 30 17 mechanical mechanical JJ cord-010055-exi8t6jt 30 18 ventilation ventilation NN cord-010055-exi8t6jt 30 19 due due IN cord-010055-exi8t6jt 30 20 to to IN cord-010055-exi8t6jt 30 21 dyspnea dyspnea NN cord-010055-exi8t6jt 30 22 and and CC cord-010055-exi8t6jt 30 23 hypoxemia hypoxemia NN cord-010055-exi8t6jt 30 24 . . . cord-010055-exi8t6jt 31 1 A a DT cord-010055-exi8t6jt 31 2 dynamic dynamic JJ cord-010055-exi8t6jt 31 3 renal renal JJ cord-010055-exi8t6jt 31 4 scintigraphy scintigraphy NN cord-010055-exi8t6jt 31 5 of of IN cord-010055-exi8t6jt 31 6 99mTc 99mtc XX cord-010055-exi8t6jt 31 7 - - HYPH cord-010055-exi8t6jt 31 8 DTPA DTPA NNP cord-010055-exi8t6jt 31 9 was be VBD cord-010055-exi8t6jt 31 10 performed perform VBN cord-010055-exi8t6jt 31 11 by by IN cord-010055-exi8t6jt 31 12 PICC PICC NNP cord-010055-exi8t6jt 31 13 in in IN cord-010055-exi8t6jt 31 14 this this DT cord-010055-exi8t6jt 31 15 critical critical JJ cord-010055-exi8t6jt 31 16 patient patient NN cord-010055-exi8t6jt 31 17 with with IN cord-010055-exi8t6jt 31 18 AKI AKI NNP cord-010055-exi8t6jt 31 19 and and CC cord-010055-exi8t6jt 31 20 artificially artificially RB cord-010055-exi8t6jt 31 21 assisted assist VBD cord-010055-exi8t6jt 31 22 ventilation ventilation NN cord-010055-exi8t6jt 31 23 . . . cord-010055-exi8t6jt 32 1 The the DT cord-010055-exi8t6jt 32 2 relative relative JJ cord-010055-exi8t6jt 32 3 renal renal JJ cord-010055-exi8t6jt 32 4 uptake uptake NN cord-010055-exi8t6jt 32 5 of of IN cord-010055-exi8t6jt 32 6 the the DT cord-010055-exi8t6jt 32 7 right right JJ cord-010055-exi8t6jt 32 8 kidney kidney NN cord-010055-exi8t6jt 32 9 was be VBD cord-010055-exi8t6jt 32 10 22,737 22,737 CD cord-010055-exi8t6jt 32 11 counts count NNS cord-010055-exi8t6jt 32 12 , , , cord-010055-exi8t6jt 32 13 the the DT cord-010055-exi8t6jt 32 14 left left JJ cord-010055-exi8t6jt 32 15 kidney kidney NN cord-010055-exi8t6jt 32 16 was be VBD cord-010055-exi8t6jt 32 17 40,310 40,310 CD cord-010055-exi8t6jt 32 18 counts count NNS cord-010055-exi8t6jt 32 19 , , , cord-010055-exi8t6jt 32 20 the the DT cord-010055-exi8t6jt 32 21 right right JJ cord-010055-exi8t6jt 32 22 kidney kidney NN cord-010055-exi8t6jt 32 23 GFR GFR NNP cord-010055-exi8t6jt 32 24 was be VBD cord-010055-exi8t6jt 32 25 14.6 14.6 CD cord-010055-exi8t6jt 32 26 mL ml NN cord-010055-exi8t6jt 32 27 / / SYM cord-010055-exi8t6jt 32 28 min min NN cord-010055-exi8t6jt 32 29 , , , cord-010055-exi8t6jt 32 30 and and CC cord-010055-exi8t6jt 32 31 the the DT cord-010055-exi8t6jt 32 32 left left JJ cord-010055-exi8t6jt 32 33 kidney kidney NN cord-010055-exi8t6jt 32 34 GFR GFR NNP cord-010055-exi8t6jt 32 35 was be VBD cord-010055-exi8t6jt 32 36 25.9 25.9 CD cord-010055-exi8t6jt 32 37 mL ml NN cord-010055-exi8t6jt 32 38 / / SYM cord-010055-exi8t6jt 32 39 min min NN cord-010055-exi8t6jt 32 40 . . . cord-010055-exi8t6jt 33 1 The the DT cord-010055-exi8t6jt 33 2 bilateral bilateral JJ cord-010055-exi8t6jt 33 3 renal renal JJ cord-010055-exi8t6jt 33 4 blood blood NN cord-010055-exi8t6jt 33 5 flow flow NN cord-010055-exi8t6jt 33 6 significantly significantly RB cord-010055-exi8t6jt 33 7 reduced reduce VBN cord-010055-exi8t6jt 33 8 and and CC cord-010055-exi8t6jt 33 9 the the DT cord-010055-exi8t6jt 33 10 renogram renogram JJ cord-010055-exi8t6jt 33 11 curves curve NNS cord-010055-exi8t6jt 33 12 shown show VBD cord-010055-exi8t6jt 33 13 a a DT cord-010055-exi8t6jt 33 14 renal renal JJ cord-010055-exi8t6jt 33 15 failure failure NN cord-010055-exi8t6jt 33 16 pattern pattern NN cord-010055-exi8t6jt 33 17 ; ; : cord-010055-exi8t6jt 33 18 the the DT cord-010055-exi8t6jt 33 19 relative relative JJ cord-010055-exi8t6jt 33 20 renal renal JJ cord-010055-exi8t6jt 33 21 uptake uptake NN cord-010055-exi8t6jt 33 22 of of IN cord-010055-exi8t6jt 33 23 each each DT cord-010055-exi8t6jt 33 24 kidney kidney NN cord-010055-exi8t6jt 33 25 indicated indicate VBD cord-010055-exi8t6jt 33 26 the the DT cord-010055-exi8t6jt 33 27 split split NN cord-010055-exi8t6jt 33 28 renal renal JJ cord-010055-exi8t6jt 33 29 function function NN cord-010055-exi8t6jt 33 30 , , , cord-010055-exi8t6jt 33 31 respectively respectively RB cord-010055-exi8t6jt 33 32 . . . cord-010055-exi8t6jt 34 1 These these DT cord-010055-exi8t6jt 34 2 findings finding NNS cord-010055-exi8t6jt 34 3 were be VBD cord-010055-exi8t6jt 34 4 most most RBS cord-010055-exi8t6jt 34 5 consistent consistent JJ cord-010055-exi8t6jt 34 6 with with IN cord-010055-exi8t6jt 34 7 renal renal JJ cord-010055-exi8t6jt 34 8 causes cause NNS cord-010055-exi8t6jt 34 9 of of IN cord-010055-exi8t6jt 34 10 acute acute JJ cord-010055-exi8t6jt 34 11 renal renal JJ cord-010055-exi8t6jt 34 12 failure failure NN cord-010055-exi8t6jt 34 13 Determining determine VBG cord-010055-exi8t6jt 34 14 the the DT cord-010055-exi8t6jt 34 15 optimal optimal JJ cord-010055-exi8t6jt 34 16 time time NN cord-010055-exi8t6jt 34 17 for for IN cord-010055-exi8t6jt 34 18 liberation liberation NN cord-010055-exi8t6jt 34 19 from from IN cord-010055-exi8t6jt 34 20 renal renal JJ cord-010055-exi8t6jt 34 21 replacement replacement NN cord-010055-exi8t6jt 34 22 therapy therapy NN cord-010055-exi8t6jt 34 23 in in IN cord-010055-exi8t6jt 34 24 critically critically RB cord-010055-exi8t6jt 34 25 ill ill JJ cord-010055-exi8t6jt 34 26 patients patient NNS cord-010055-exi8t6jt 34 27 : : : cord-010055-exi8t6jt 34 28 a a DT cord-010055-exi8t6jt 34 29 systematic systematic JJ cord-010055-exi8t6jt 34 30 review review NN cord-010055-exi8t6jt 34 31 and and CC cord-010055-exi8t6jt 34 32 meta meta NNP cord-010055-exi8t6jt 34 33 - - HYPH cord-010055-exi8t6jt 34 34 analysis analysis NN cord-010055-exi8t6jt 34 35 ( ( -LRB- cord-010055-exi8t6jt 34 36 DOnE DOnE NNP cord-010055-exi8t6jt 34 37 RRT RRT NNP cord-010055-exi8t6jt 34 38 ) ) -RRB- cord-010055-exi8t6jt 34 39 Estimating estimating NN cord-010055-exi8t6jt 34 40 and and CC cord-010055-exi8t6jt 34 41 measuring measure VBG cord-010055-exi8t6jt 34 42 glomerular glomerular JJ cord-010055-exi8t6jt 34 43 filtration filtration NN cord-010055-exi8t6jt 34 44 rate rate NN cord-010055-exi8t6jt 34 45 : : : cord-010055-exi8t6jt 34 46 methods method NNS cord-010055-exi8t6jt 34 47 of of IN cord-010055-exi8t6jt 34 48 measurement measurement NN cord-010055-exi8t6jt 34 49 and and CC cord-010055-exi8t6jt 34 50 markers marker NNS cord-010055-exi8t6jt 34 51 for for IN cord-010055-exi8t6jt 34 52 estimation estimation NN cord-010055-exi8t6jt 35 1 The the DT cord-010055-exi8t6jt 35 2 SNMMI SNMMI NNP cord-010055-exi8t6jt 35 3 and and CC cord-010055-exi8t6jt 35 4 EANM EANM NNP cord-010055-exi8t6jt 35 5 practice practice NN cord-010055-exi8t6jt 35 6 guideline guideline NN cord-010055-exi8t6jt 35 7 for for IN cord-010055-exi8t6jt 35 8 renal renal JJ cord-010055-exi8t6jt 35 9 scintigraphy scintigraphy NN cord-010055-exi8t6jt 35 10 in in IN cord-010055-exi8t6jt 35 11 adults adult NNS cord-010055-exi8t6jt 36 1 ACR ACR NNP cord-010055-exi8t6jt 36 2 Appropriateness appropriateness NN cord-010055-exi8t6jt 36 3 Criteria Criteria NNP cord-010055-exi8t6jt 36 4 ( ( -LRB- cord-010055-exi8t6jt 37 1 ® ® LS cord-010055-exi8t6jt 37 2 ) ) -RRB- cord-010055-exi8t6jt 37 3 radiologic radiologic JJ cord-010055-exi8t6jt 37 4 management management NN cord-010055-exi8t6jt 37 5 of of IN cord-010055-exi8t6jt 37 6 central central JJ cord-010055-exi8t6jt 37 7 venous venous JJ cord-010055-exi8t6jt 37 8 access access NNP cord-010055-exi8t6jt 37 9 Publisher Publisher NNP cord-010055-exi8t6jt 37 10 's 's POS cord-010055-exi8t6jt 37 11 Note Note NNP cord-010055-exi8t6jt 37 12 Springer Springer NNP cord-010055-exi8t6jt 37 13 Nature Nature NNP cord-010055-exi8t6jt 37 14 remains remain VBZ cord-010055-exi8t6jt 37 15 neutral neutral JJ cord-010055-exi8t6jt 37 16 with with IN cord-010055-exi8t6jt 37 17 regard regard NN cord-010055-exi8t6jt 37 18 to to IN cord-010055-exi8t6jt 37 19 jurisdictional jurisdictional JJ cord-010055-exi8t6jt 37 20 claims claim NNS cord-010055-exi8t6jt 37 21 in in IN cord-010055-exi8t6jt 37 22 published publish VBN cord-010055-exi8t6jt 37 23 maps map NNS cord-010055-exi8t6jt 37 24 and and CC cord-010055-exi8t6jt 37 25 institutional institutional JJ cord-010055-exi8t6jt 37 26 affiliations affiliation NNS cord-010055-exi8t6jt 37 27 None none NN cord-010055-exi8t6jt 37 28 . . . cord-010055-exi8t6jt 38 1 Authors author NNS cord-010055-exi8t6jt 38 2 ' ' POS cord-010055-exi8t6jt 38 3 contributions contribution NNS cord-010055-exi8t6jt 38 4 GW GW NNP cord-010055-exi8t6jt 38 5 , , , cord-010055-exi8t6jt 38 6 Zhu Zhu NNP cord-010055-exi8t6jt 38 7 contributed contribute VBD cord-010055-exi8t6jt 38 8 to to IN cord-010055-exi8t6jt 38 9 the the DT cord-010055-exi8t6jt 38 10 designing designing NN cord-010055-exi8t6jt 38 11 , , , cord-010055-exi8t6jt 38 12 drafting draft VBG cord-010055-exi8t6jt 38 13 , , , cord-010055-exi8t6jt 38 14 and and CC cord-010055-exi8t6jt 38 15 reviewing review VBG cord-010055-exi8t6jt 38 16 the the DT cord-010055-exi8t6jt 38 17 paper paper NN cord-010055-exi8t6jt 38 18 . . . cord-010055-exi8t6jt 39 1 Z Z NNP cord-010055-exi8t6jt 39 2 , , , cord-010055-exi8t6jt 39 3 Gao Gao NNP cord-010055-exi8t6jt 39 4 contributed contribute VBD cord-010055-exi8t6jt 39 5 equally equally RB cord-010055-exi8t6jt 39 6 with with IN cord-010055-exi8t6jt 39 7 GW GW NNP cord-010055-exi8t6jt 39 8 , , , cord-010055-exi8t6jt 39 9 Zhu Zhu NNP cord-010055-exi8t6jt 39 10 ; ; : cord-010055-exi8t6jt 39 11 H H NNP cord-010055-exi8t6jt 39 12 , , , cord-010055-exi8t6jt 39 13 Liu Liu NNP cord-010055-exi8t6jt 39 14 and and CC cord-010055-exi8t6jt 39 15 Abdoul Abdoul NNP cord-010055-exi8t6jt 39 16 Rachid Rachid NNP cord-010055-exi8t6jt 39 17 participated participate VBD cord-010055-exi8t6jt 39 18 in in IN cord-010055-exi8t6jt 39 19 the the DT cord-010055-exi8t6jt 39 20 data data NN cord-010055-exi8t6jt 39 21 analysis analysis NN cord-010055-exi8t6jt 39 22 . . . cord-010055-exi8t6jt 40 1 All all DT cord-010055-exi8t6jt 40 2 authors author NNS cord-010055-exi8t6jt 40 3 approved approve VBD cord-010055-exi8t6jt 40 4 the the DT cord-010055-exi8t6jt 40 5 final final JJ cord-010055-exi8t6jt 40 6 manuscript manuscript NN cord-010055-exi8t6jt 40 7 . . . cord-010055-exi8t6jt 41 1 Availability availability NN cord-010055-exi8t6jt 41 2 of of IN cord-010055-exi8t6jt 41 3 data datum NNS cord-010055-exi8t6jt 41 4 and and CC cord-010055-exi8t6jt 41 5 materials material NNS cord-010055-exi8t6jt 41 6 Not not RB cord-010055-exi8t6jt 41 7 applicable applicable JJ cord-010055-exi8t6jt 41 8 . . . cord-010055-exi8t6jt 42 1 Ethics ethic NNS cord-010055-exi8t6jt 42 2 approval approval NN cord-010055-exi8t6jt 42 3 and and CC cord-010055-exi8t6jt 42 4 consent consent NN cord-010055-exi8t6jt 42 5 to to TO cord-010055-exi8t6jt 42 6 participate participate VB cord-010055-exi8t6jt 42 7 Not not RB cord-010055-exi8t6jt 42 8 applicable applicable JJ cord-010055-exi8t6jt 42 9 . . . cord-010055-exi8t6jt 43 1 Not not RB cord-010055-exi8t6jt 43 2 applicable applicable JJ cord-010055-exi8t6jt 43 3 . . . cord-010055-exi8t6jt 44 1 The the DT cord-010055-exi8t6jt 44 2 authors author NNS cord-010055-exi8t6jt 44 3 declare declare VBP cord-010055-exi8t6jt 44 4 that that IN cord-010055-exi8t6jt 44 5 they -PRON- PRP cord-010055-exi8t6jt 44 6 have have VBP cord-010055-exi8t6jt 44 7 no no DT cord-010055-exi8t6jt 44 8 competing compete VBG cord-010055-exi8t6jt 44 9 interests interest NNS cord-010055-exi8t6jt 44 10 . . .