id author title date pages extension mime words sentences flesch summary cache txt cord-305076-v56y5nyt Singh, Parmvir Disseminated Intravascular Coagulation: A Devastating Systemic Disorder of Special Concern with COVID‐19 2020-07-23 .txt text/plain 2911 247 44 Clinical patterns with DIC are varied, exemplified by those identified with COVID-19, from petechial to acro-ischemia presentations including finger/toe cyanosis, skin bulla and dry gangrene, some resembling chilblains disease (Figures 1,2) 7 . 8, 15 Skin manifestations caused by thrombosis include acral cyanosis (25%) and gangrene (17%). 8 It is important to differentiate the thrombotic/coagulopathic vasculopathic acral ischemia as seen in DIC from chilblain-like lesions (blue "COVID toes"), also associated with the This article is protected by copyright. 1,24,43-46 COVID-19-associated DIC therapy should follow accepted strategy employing thromboembolic prophylaxis for critically ill hospitalized patients and standard supportive care measures 47 . Presentation and outcome of purpura fulminans associated with peripheral gangrene in 12 patients at Mayo Clinic Comparison of a new criteria for sepsis-induced coagulopathy and International Society on Thrombosis and Haemostasis disseminated intravascular coagulation score in critically ill patients with sepsis 3.0: a retrospective study ./cache/cord-305076-v56y5nyt.txt ./txt/cord-305076-v56y5nyt.txt