id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-331687-o5031cxp	Singh, Yogendra	RAAS blockers in hypertension posing a higher risk towards the COVID‐19	2020-05-02		.txt	text/plain	601	38	57	Most of the hypertensive patients are assisted by angiotensin converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) or both. A recently published study suggested that COVID-19 also uses ACE2 as a cellular entry receptor, as this was detected in the isolates of the bronchoalveolar lavage fluid of one of the critically ill patients 4 . There is enough evidence to believe that the Zoonotic COVID-19 is completely dependent on human ACE2 as a receptor for entry, thus having high replication potential in human cells. Thus, patients who adhere to RAAS blockers (assisted with ACEi or ARBs) are believed to have a higher risk towards the deadly viral attack of COVID-19, and progressively they must be switched on to other class of anti-hypertensive drugs. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody	./cache/cord-331687-o5031cxp.txt	./txt/cord-331687-o5031cxp.txt