key: cord-336695-jx0waah0 authors: Kroumpouzos, George; Gupta, Mrinal; Jafferany, Mohammad; Lotti, Torello; Sadoughifar, Roxanna; Sitkowska, Zuzanna; Goldust, Mohamad title: COVID‐19: A relationship to climate and environmental conditions? date: 2020-04-24 journal: Dermatol Ther DOI: 10.1111/dth.13399 sha: doc_id: 336695 cord_uid: jx0waah0 nan has spread rapidly throughout the world, and World Health Organization declared it a health emergency. 1-3 A significant number of infectious diseases, including human CoVs, display seasonal patterns in their incidence. Environmental factors such as temperature and humidity play an important role in progression and spread of severe acute respiratory syndrome (SARS)-CoV infection with the virus retaining its viability for over 5 days at temperatures of 22 C to 25 C and relative humidity (RH) of 40% to 50%. Higher temperatures and higher RH (38 C, and >95% RH) have been found to reduce virus viability. 4, 5 COVID-19, caused by SARS-CoV-2, started in low temperature areas of China, with major outbreaks following in South Korea, Japan, Iran, and Northern Italy. It is noteworthy that the new epicenters of virus showed similar temperature and latitude and were all along the 30 to 0 N 00 zone. The diseases then spread to higher temperature areas like India, Thailand, and Middle East, which can be attributed to the global traveling. Weather patterns in COVID-19 (5 C-11 C and 47%-70% RH) are similar to those of SARS-CoV mentioned above and known laboratory conditions that favor CoV survival (4 C, 20%-80% RH). 5 Nevertheless, the dynamics of viral transmission depend on many other factors like physical property of the virus, outdoor and indoor environments, population densities, hygiene, space, and genetic predispositions, which may be the reason for its spread in relatively warmer areas. 6, 7 The presence of central air-conditioning, which tends to maintain a lower ambient room temperature, may play a role in virus spread in closed spaces irrespective of the outside temperature. Lack of hygiene, close contact as seen in high density population areas, poor living conditions with lack of ventilation may be predisposing factors for viral transmission in warmer areas. 6, 7 The seasonality and dynamics of COVID-19 are not well under- World Health Organization declares global emergency: a review of the 2019 novel coronavirus (COVID-19) COVID-19 and psoriasis: is it time to limit treatment with immunosuppressants? A call for action Learning from history: coronavirus outbreaks in the past The effects of temperature and relative humidity on the viability of the SARS coronavirus Effects of air temperature and relative humidity on coronavirus survival on surfaces Clinical features of patients infected with 2019 novel coronavirus in Wuhan Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia