id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006174-xrhqisii	López-Rodríguez, M.	IFITM3 and severe influenza virus infection. No evidence of genetic association	2016-08-04		.txt	text/plain	2781	163	52	In the present study, we assessed whether the IFITM3 rs12252-C allele is associated with susceptibility to and severity of influenza virus infection (IVI) among a white Spanish population. We performed a case-control genetic association study aimed to analyze the role of the IFITM3 rs12252 polymorphism in the susceptibility and severity of IVI. When the different groups of patients were compared according to severity of infection (development of PVP, ARDS or acute respiratory failure, need of ICU admission or hospital mortality), no significant associations were found (data not shown). [9] found three homozygous individuals for the variant rs12252-C among 53 patients from the United Kingdom hospitalized with influenza (89.5 % H1N1pdm), resulting in a significant overrepresentation when compared with Europeans. These studies suggested that homozygosity for the IFITM3 rs12252-C allele was associated with a populationattributable risk for severe influenza of 5.4 % in Northern Europeans and 54.3 % for severe H1N1pdm infection in Chinese [9, 12] .	./cache/cord-006174-xrhqisii.txt	./txt/cord-006174-xrhqisii.txt