id author title date pages extension mime words sentences flesch summary cache txt cord-006581-f957o5z3 Gizzi, M. Another case of “European hantavirus pulmonary syndrome” with severe lung, prior to kidney, involvement, and diagnosed by viral inclusions in lung macrophages 2013-05-14 .txt text/plain 2423 134 48 The most important pathogens are Hantaan virus and Seoul virus in the Far East (>90 % of worldwide infections), Puumala virus (PUUV) and Dobrava-Belgrade virus in Europe and Russia, and, finally, Sin Nombre virus and Andes virus in the Americas [1, 2] Until recently, two clinical syndromes were classically described: hantavirus (cardio-)pulmonary syndrome (HPS or HCPS) described since 1994 in the Americas [4] and hemorrhagic fever with renal syndrome (HFRS) or its milder form nephropathia epidemica (NE), known in Eurasia since the early 1930s. The history of our patient fulfills most of the eight clinical findings specified in the "Hantavirus Pulmonary Syndrome Case Report Form", as issued by the Centers for Disease Control and Prevention (CDC), Atlanta, GA [13] : (1) fever, (2) thrombocytopenia, (3) elevated hematocrit, (4) elevated serum creatinine, (5) left shift leukocytosis with "atypical lymphocytes", (6) need for supplemental oxygen, (7) need for intubation (and mechanical ventilation), and (8) chest radiograph showing unexplained bilateral infiltrates or being suggestive of adult respiratory distress syndrome (ARDS). ./cache/cord-006581-f957o5z3.txt ./txt/cord-006581-f957o5z3.txt