id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006766-u31go6xi	Lepur, D.	Prospective observational cohort study of cerebrovascular CO(2) reactivity in patients with inflammatory CNS diseases	2011-01-29		.txt	text/plain	3920	223	46	The aim of this study was to assess the cerebrovascular CO 2 R measured by TCD using the breath-holding method in patients with inflammatory central nervous system (CNS) diseases. The following parameters were recorded in a database: age, gender, physical and neurological signs, mechanical ventilation (MV), cerebrospinal fluid (CSF) characteristics, microbiological findings in CSF and blood, mean arterial pressure (MAP), Glasgow Coma Scale (GCS) score, Glasgow Outcome Scale (GOS) score, and the mean breath-holding index (BHI m ). Non-bacterial inflammatory CNS disease (NBM) was diagnosed on the basis of present encephalopathy with at least one of the following: fever, seizures, focal neurological findings; pleocytosis with increased protein concentration in the CSF; and a positive CSF or blood culture (fungal meningitis); virus detection by PCR assay in CSF samples; proved intrathecal antibody production and electroencephalographic or neuroimaging findings consistent with encephalitis or acute disseminated encephalomyelitis (ADEM). This prospective study assessed cerebrovascular reactivity (CO 2 R) by TCD using the breath-holding method in patients with inflammatory CNS diseases.	./cache/cord-006766-u31go6xi.txt	./txt/cord-006766-u31go6xi.txt