id author title date pages extension mime words sentences flesch summary cache txt cord-294551-s3nsiano Muller, M. P. Early diagnosis of SARS: lessons from the Toronto SARS outbreak 2006-04-04 .txt text/plain 3638 160 47 To identify features of the clinical assessment that are useful in SARS diagnosis, the exposure status and the prevalence and timing of symptoms, signs, laboratory and radiographic findings were determined for all adult patients admitted with suspected SARS during the Toronto SARS outbreak. Patients were classified as confirmed SARS if they had a compatible clinical illness (fever or nonproductive cough or dyspnea), an exposure to SARS (direct contact with a known SARS case or travel to a SARS-endemic area or time spent at an institution where SARS transmission was occurring, within 12 days of symptom onset), and a positive microbiological test (positive acute or convalescent serology, or positive PCR from clinical or pathological specimens). Findings associated with a confirmed diagnosis included direct exposure to a known case (OR, 2.34; 95%CI, 1.01-5.40), symptomatic fever as an initial symptom (OR, 5.07; 95%CI, 2.24-11.50), a documented temperature of 38.0°C on admission to hospital (OR, 2.6; 95%CI, 1.14-5.92), and the presence of a pulmonary infiltrate by the time of admission (OR, 2.46; 95%CI, 1.09-5.56). ./cache/cord-294551-s3nsiano.txt ./txt/cord-294551-s3nsiano.txt