id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325238-2nhade3s	Seleem, Noura M.	Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections	2020-04-23		.txt	text/plain	8486	478	50	The studied virulence factors include biofilm formation, twitching and swarming motilities, proteolytic enzyme production, and resistance to oxidative stress. The virulence factors were detected in absence and presence of 1 8 MIC of potential QSIs. Assay of biofilm formation, twitching motility, sensitivity to oxidative stress and protease, and gelatinase activity were performed for both P. Among the tested drugs, erythromycin, levamisole, propranolol, and chloroquine showed the highest inhibition of quorum sensing in CV026 as they produced a large clear zone around each well on a purple background (Fig. 1) ; hence, these four drugs were tested in the further experiments. The obtained results revealed that PAO1 biofilm (strong) was markedly inhibited in presence of 1/8 MIC of tested drugs (> 68%); the highest inhibition was observed with erythromycin (82.7%) as shown in Table 2 and Fig. 2a .	./cache/cord-325238-2nhade3s.txt	./txt/cord-325238-2nhade3s.txt