id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003319-u88gznxq	Huang, Weishan	Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages	2018-11-19		.txt	text/plain	6298	313	53	To determine whether co-expression of LAG3 and CD49b is exclusive to Foxp3 − Tr1 cell subset, we infected IL-10 GFP /Foxp3 RFP dual reporter mice with Nb, and analyzed the IL-10-producing T cells. Along with the model of parasitic infection shown in Figure 2 , our data suggest that co-expression of LAG3 and CD49b marks all IL-10-producing T cell lineages in the pulmonary system, and relative abundance of the marked T cell subsets is dependent on the type of immune response as shown in the disease models. Despite the shared feature of co-expression of LAG3 and CD49b by IL-10-producing Foxp3 + CD4 + , Foxp3 − CD4 + , and CD8 + T cells, we also observed interesting discrepancies in the proportional composition of these three IL-10 high T cell subsets that are all LAG3/CD49b double positive in the lung mucosa of different pulmonary inflammatory disease models, as well as in different anatomical locations in the same mice upon TCR activation in vivo.	./cache/cord-003319-u88gznxq.txt	./txt/cord-003319-u88gznxq.txt