id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003368-f8f2utzx	Lutterberg, Karina	A Functionally Different Immune Phenotype in Cattle Is Associated With Higher Mastitis Incidence	2018-12-06		.txt	text/plain	5053	287	46	After in vitro stimulation of peripheral blood derived lymphocytes (PBL), we detected distinctly deviant expression levels of several master regulators of immune responses in BNP cells, pointing to a changed immune phenotype with severe dysregulation of immune response in BNP cows. As other authors claimed the possibility of a genetic predisposition of BNP dams for production of BNP inducing alloantibodies (22) (23) (24) , our studies focused on investigating a general difference in immune responses between PregSure BVD vaccinated control cows and BNP donors. In in vitro proliferation assays with T cell mitogen ConA we observed that 22% of the unvaccinated cows reacted similar to BNP dams by showing a hyperproliferative reaction to ConA (immune deviant (ID) phenotype; Figure 6A , reaction difference ID to controls or BNP to controls, * * * * p < 0.0001).	./cache/cord-003368-f8f2utzx.txt	./txt/cord-003368-f8f2utzx.txt