id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-300429-b0zev8zb	Sobocińska, Justyna	Protein Palmitoylation and Its Role in Bacterial and Viral Infections	2018-01-19		.txt	text/plain	13428	587	40	We highlight recent data on protein S-palmitoylation in pathogens and their hosts obtained owing to the development of methods based on click chemistry and acyl-biotin exchange allowing proteomic analysis of protein lipidation. Given the large variety of chemical reporters preferentially mimicking distinct fatty acids, recent years have witnessed a plethora of chemistry-based proteomic studies not only on palmitoylated but also myristoylated proteins and proteins bearing the GPI anchor, including those of pathogens and immune cells (10, 14, 85, 86, 114) The aBe Method Reveals Protein The envelope is rich in transmembrane, often S-palmitoylated, glycoproteins called spikes, which can bind to cognate receptors on the host cell plasma membrane triggering endocytosis of the virion, mediate subsequent fusion of the viral and cellular membranes allowing entry of the viral genome to the cytoplasm, and are also involved in the budding of newly formed virus particles from the cell.	./cache/cord-300429-b0zev8zb.txt	./txt/cord-300429-b0zev8zb.txt