id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317797-h229skaq	Li, Conglei	Crosstalk Between Platelets and Microbial Pathogens	2020-08-07		.txt	text/plain	7628	409	33	For example, thrombocytopenia in children following varicella zoster virus infection first described antigenic mimicry for some microbial pathogens that encompass host generation of crossreactive antibodies to certain glycoproteins (e.g., GPIIIa) on the platelet surface, resulting in accelerated platelet clearance (117) . In addition to the effects on platelet count and function, microbial pathogens impact the host auto-and alloimmune response to platelet antigens in several immune-mediated diseases, such as immune thrombocytopenia (ITP), and fetal and neonatal alloimmune thrombocytopenia (FNAIT) (99-101) (Figure 3) . C-reactive protein is markedly upregulated during acute infections and inflammation (178) , and it has been shown that C-reactive protein, via binding to platelet phosphorylcholine residues, enhanced the IgG-mediated phagocytic responses against platelets and thereby thrombocytopenia, which has implications in the pathogenesis of both ITP and FNAIT (123, 124) .	./cache/cord-317797-h229skaq.txt	./txt/cord-317797-h229skaq.txt