id	sid	tid	token	lemma	pos
cord-278081-tk7vn1v1	1	1	key	key	JJ
cord-278081-tk7vn1v1	1	2	:	:	:
cord-278081-tk7vn1v1	1	3	cord-278081-tk7vn1v1	cord-278081-tk7vn1v1	NN
cord-278081-tk7vn1v1	1	4	authors	author	NNS
cord-278081-tk7vn1v1	1	5	:	:	:
cord-278081-tk7vn1v1	1	6	Brooks	Brooks	NNP
cord-278081-tk7vn1v1	1	7	,	,	,
cord-278081-tk7vn1v1	1	8	Wesley	Wesley	NNP
cord-278081-tk7vn1v1	1	9	H.	H.	NNP
cord-278081-tk7vn1v1	1	10	title	title	NN
cord-278081-tk7vn1v1	1	11	:	:	:
cord-278081-tk7vn1v1	1	12	Viral	Viral	NNP
cord-278081-tk7vn1v1	1	13	Impact	Impact	NNP
cord-278081-tk7vn1v1	1	14	in	in	IN
cord-278081-tk7vn1v1	1	15	Autoimmune	Autoimmune	NNP
cord-278081-tk7vn1v1	1	16	Diseases	Diseases	NNPS
cord-278081-tk7vn1v1	1	17	:	:	:
cord-278081-tk7vn1v1	2	1	Expanding	expand	VBG
cord-278081-tk7vn1v1	2	2	the	the	DT
cord-278081-tk7vn1v1	2	3	“	"	``
cord-278081-tk7vn1v1	2	4	X	X	NNP
cord-278081-tk7vn1v1	2	5	Chromosome	chromosome	NN
cord-278081-tk7vn1v1	2	6	–	–	:
cord-278081-tk7vn1v1	2	7	Nucleolus	Nucleolus	NNP
cord-278081-tk7vn1v1	2	8	Nexus	Nexus	NNP
cord-278081-tk7vn1v1	2	9	”	"	''
cord-278081-tk7vn1v1	2	10	Hypothesis	Hypothesis	NNP
cord-278081-tk7vn1v1	2	11	date	date	NN
cord-278081-tk7vn1v1	2	12	:	:	:
cord-278081-tk7vn1v1	2	13	2017	2017	CD
cord-278081-tk7vn1v1	2	14	-	-	HYPH
cord-278081-tk7vn1v1	2	15	11	11	CD
cord-278081-tk7vn1v1	2	16	-	-	SYM
cord-278081-tk7vn1v1	2	17	28	28	CD
cord-278081-tk7vn1v1	2	18	journal	journal	NN
cord-278081-tk7vn1v1	2	19	:	:	:
cord-278081-tk7vn1v1	3	1	Front	Front	NNP
cord-278081-tk7vn1v1	3	2	Immunol	Immunol	NNP
cord-278081-tk7vn1v1	3	3	DOI	doi	NN
cord-278081-tk7vn1v1	3	4	:	:	:
cord-278081-tk7vn1v1	4	1	10.3389/	10.3389/	CD
cord-278081-tk7vn1v1	5	1	fimmu.2017.01657	fimmu.2017.01657	NNP
cord-278081-tk7vn1v1	5	2	sha	sha	NNP
cord-278081-tk7vn1v1	5	3	:	:	:
cord-278081-tk7vn1v1	5	4	8495f7c65f4a6cbce0e0d53c0900f10f6740826e	8495f7c65f4a6cbce0e0d53c0900f10f6740826e	.
cord-278081-tk7vn1v1	5	5	doc_id	doc_id	CD
cord-278081-tk7vn1v1	5	6	:	:	:
cord-278081-tk7vn1v1	5	7	278081	278081	CD
cord-278081-tk7vn1v1	5	8	cord_uid	cord_uid	NNS
cord-278081-tk7vn1v1	5	9	:	:	:
cord-278081-tk7vn1v1	6	1	tk7vn1v1	tk7vn1v1	NNP
cord-278081-tk7vn1v1	7	1	Viruses	virus	NNS
cord-278081-tk7vn1v1	7	2	are	be	VBP
cord-278081-tk7vn1v1	7	3	suspected	suspect	VBN
cord-278081-tk7vn1v1	7	4	of	of	IN
cord-278081-tk7vn1v1	7	5	significant	significant	JJ
cord-278081-tk7vn1v1	7	6	roles	role	NNS
cord-278081-tk7vn1v1	7	7	in	in	IN
cord-278081-tk7vn1v1	7	8	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	7	9	diseases	disease	NNS
cord-278081-tk7vn1v1	7	10	but	but	CC
cord-278081-tk7vn1v1	7	11	the	the	DT
cord-278081-tk7vn1v1	7	12	mechanisms	mechanism	NNS
cord-278081-tk7vn1v1	7	13	are	be	VBP
cord-278081-tk7vn1v1	7	14	unclear	unclear	JJ
cord-278081-tk7vn1v1	7	15	.	.	.
cord-278081-tk7vn1v1	8	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	8	2	get	get	VBP
cord-278081-tk7vn1v1	8	3	some	some	DT
cord-278081-tk7vn1v1	8	4	insight	insight	NN
cord-278081-tk7vn1v1	8	5	by	by	IN
cord-278081-tk7vn1v1	8	6	considering	consider	VBG
cord-278081-tk7vn1v1	8	7	demands	demand	VBZ
cord-278081-tk7vn1v1	8	8	a	a	DT
cord-278081-tk7vn1v1	8	9	virus	virus	NN
cord-278081-tk7vn1v1	8	10	places	place	VBZ
cord-278081-tk7vn1v1	8	11	on	on	IN
cord-278081-tk7vn1v1	8	12	host	host	NN
cord-278081-tk7vn1v1	8	13	cells	cell	NNS
cord-278081-tk7vn1v1	8	14	.	.	.
cord-278081-tk7vn1v1	9	1	Viruses	virus	NNS
cord-278081-tk7vn1v1	9	2	not	not	RB
cord-278081-tk7vn1v1	9	3	only	only	RB
cord-278081-tk7vn1v1	9	4	require	require	VBP
cord-278081-tk7vn1v1	9	5	production	production	NN
cord-278081-tk7vn1v1	9	6	of	of	IN
cord-278081-tk7vn1v1	9	7	their	-PRON-	PRP$
cord-278081-tk7vn1v1	9	8	own	own	JJ
cord-278081-tk7vn1v1	9	9	proteins	protein	NNS
cord-278081-tk7vn1v1	9	10	,	,	,
cord-278081-tk7vn1v1	9	11	RNA	RNA	NNP
cord-278081-tk7vn1v1	9	12	and/or	and/or	CC
cord-278081-tk7vn1v1	9	13	DNA	DNA	NNP
cord-278081-tk7vn1v1	9	14	,	,	,
cord-278081-tk7vn1v1	9	15	but	but	CC
cord-278081-tk7vn1v1	9	16	also	also	RB
cord-278081-tk7vn1v1	9	17	production	production	NN
cord-278081-tk7vn1v1	9	18	of	of	IN
cord-278081-tk7vn1v1	9	19	additional	additional	JJ
cord-278081-tk7vn1v1	9	20	cellular	cellular	JJ
cord-278081-tk7vn1v1	9	21	machinery	machinery	NN
cord-278081-tk7vn1v1	9	22	,	,	,
cord-278081-tk7vn1v1	9	23	such	such	JJ
cord-278081-tk7vn1v1	9	24	as	as	IN
cord-278081-tk7vn1v1	9	25	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	9	26	,	,	,
cord-278081-tk7vn1v1	9	27	to	to	TO
cord-278081-tk7vn1v1	9	28	handle	handle	VB
cord-278081-tk7vn1v1	9	29	the	the	DT
cord-278081-tk7vn1v1	9	30	increased	increase	VBN
cord-278081-tk7vn1v1	9	31	demands	demand	NNS
cord-278081-tk7vn1v1	9	32	.	.	.
cord-278081-tk7vn1v1	10	1	Since	since	IN
cord-278081-tk7vn1v1	10	2	the	the	DT
cord-278081-tk7vn1v1	10	3	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	10	4	is	be	VBZ
cord-278081-tk7vn1v1	10	5	a	a	DT
cord-278081-tk7vn1v1	10	6	major	major	JJ
cord-278081-tk7vn1v1	10	7	site	site	NN
cord-278081-tk7vn1v1	10	8	of	of	IN
cord-278081-tk7vn1v1	10	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	10	10	processing	processing	NN
cord-278081-tk7vn1v1	10	11	and	and	CC
cord-278081-tk7vn1v1	10	12	ribonucleoprotein	ribonucleoprotein	NNP
cord-278081-tk7vn1v1	10	13	assembly	assembly	NNP
cord-278081-tk7vn1v1	10	14	,	,	,
cord-278081-tk7vn1v1	10	15	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	10	16	are	be	VBP
cord-278081-tk7vn1v1	10	17	targeted	target	VBN
cord-278081-tk7vn1v1	10	18	by	by	IN
cord-278081-tk7vn1v1	10	19	viruses	virus	NNS
cord-278081-tk7vn1v1	10	20	,	,	,
cord-278081-tk7vn1v1	10	21	directly	directly	RB
cord-278081-tk7vn1v1	10	22	when	when	WRB
cord-278081-tk7vn1v1	10	23	viral	viral	JJ
cord-278081-tk7vn1v1	10	24	RNA	RNA	NNP
cord-278081-tk7vn1v1	10	25	and	and	CC
cord-278081-tk7vn1v1	10	26	proteins	protein	NNS
cord-278081-tk7vn1v1	10	27	enter	enter	VBP
cord-278081-tk7vn1v1	10	28	the	the	DT
cord-278081-tk7vn1v1	10	29	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	10	30	and	and	CC
cord-278081-tk7vn1v1	10	31	indirectly	indirectly	RB
cord-278081-tk7vn1v1	10	32	when	when	WRB
cord-278081-tk7vn1v1	10	33	viruses	virus	NNS
cord-278081-tk7vn1v1	10	34	induce	induce	VBP
cord-278081-tk7vn1v1	10	35	increased	increase	VBN
cord-278081-tk7vn1v1	10	36	expression	expression	NN
cord-278081-tk7vn1v1	10	37	of	of	IN
cord-278081-tk7vn1v1	10	38	cellular	cellular	JJ
cord-278081-tk7vn1v1	10	39	polyamine	polyamine	NN
cord-278081-tk7vn1v1	10	40	genes	gene	NNS
cord-278081-tk7vn1v1	10	41	.	.	.
cord-278081-tk7vn1v1	11	1	Polyamines	polyamine	NNS
cord-278081-tk7vn1v1	11	2	are	be	VBP
cord-278081-tk7vn1v1	11	3	at	at	IN
cord-278081-tk7vn1v1	11	4	high	high	JJ
cord-278081-tk7vn1v1	11	5	levels	level	NNS
cord-278081-tk7vn1v1	11	6	in	in	IN
cord-278081-tk7vn1v1	11	7	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	11	8	to	to	TO
cord-278081-tk7vn1v1	11	9	assist	assist	VB
cord-278081-tk7vn1v1	11	10	in	in	IN
cord-278081-tk7vn1v1	11	11	RNA	RNA	NNP
cord-278081-tk7vn1v1	11	12	folding	folding	NN
cord-278081-tk7vn1v1	11	13	.	.	.
cord-278081-tk7vn1v1	12	1	The	the	DT
cord-278081-tk7vn1v1	12	2	size	size	NN
cord-278081-tk7vn1v1	12	3	and	and	CC
cord-278081-tk7vn1v1	12	4	activity	activity	NN
cord-278081-tk7vn1v1	12	5	of	of	IN
cord-278081-tk7vn1v1	12	6	nucleoli	nucleoli	JJ
cord-278081-tk7vn1v1	12	7	increase	increase	VBP
cord-278081-tk7vn1v1	12	8	directly	directly	RB
cord-278081-tk7vn1v1	12	9	with	with	IN
cord-278081-tk7vn1v1	12	10	increases	increase	NNS
cord-278081-tk7vn1v1	12	11	in	in	IN
cord-278081-tk7vn1v1	12	12	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	12	13	.	.	.
cord-278081-tk7vn1v1	13	1	Nucleolar	Nucleolar	NNP
cord-278081-tk7vn1v1	13	2	expansion	expansion	NN
cord-278081-tk7vn1v1	13	3	due	due	IN
cord-278081-tk7vn1v1	13	4	to	to	IN
cord-278081-tk7vn1v1	13	5	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	13	6	increases	increase	NNS
cord-278081-tk7vn1v1	13	7	in	in	IN
cord-278081-tk7vn1v1	13	8	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	13	9	could	could	MD
cord-278081-tk7vn1v1	13	10	disrupt	disrupt	VB
cord-278081-tk7vn1v1	13	11	nearby	nearby	JJ
cord-278081-tk7vn1v1	13	12	chromatin	chromatin	NN
cord-278081-tk7vn1v1	13	13	,	,	,
cord-278081-tk7vn1v1	13	14	such	such	JJ
cord-278081-tk7vn1v1	13	15	as	as	IN
cord-278081-tk7vn1v1	13	16	the	the	DT
cord-278081-tk7vn1v1	13	17	inactive	inactive	JJ
cord-278081-tk7vn1v1	13	18	X	x	NN
cord-278081-tk7vn1v1	13	19	chromosome	chromosome	NN
cord-278081-tk7vn1v1	13	20	,	,	,
cord-278081-tk7vn1v1	13	21	leading	lead	VBG
cord-278081-tk7vn1v1	13	22	to	to	IN
cord-278081-tk7vn1v1	13	23	expression	expression	NN
cord-278081-tk7vn1v1	13	24	of	of	IN
cord-278081-tk7vn1v1	13	25	previously	previously	RB
cord-278081-tk7vn1v1	13	26	sequestered	sequester	VBN
cord-278081-tk7vn1v1	13	27	DNA	dna	NN
cord-278081-tk7vn1v1	13	28	.	.	.
cord-278081-tk7vn1v1	14	1	Sudden	sudden	JJ
cord-278081-tk7vn1v1	14	2	expression	expression	NN
cord-278081-tk7vn1v1	14	3	of	of	IN
cord-278081-tk7vn1v1	14	4	a	a	DT
cord-278081-tk7vn1v1	14	5	large	large	JJ
cord-278081-tk7vn1v1	14	6	concentration	concentration	NN
cord-278081-tk7vn1v1	14	7	of	of	IN
cord-278081-tk7vn1v1	14	8	Alu	Alu	NNP
cord-278081-tk7vn1v1	14	9	elements	element	NNS
cord-278081-tk7vn1v1	14	10	from	from	IN
cord-278081-tk7vn1v1	14	11	the	the	DT
cord-278081-tk7vn1v1	14	12	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	14	13	inactive	inactive	JJ
cord-278081-tk7vn1v1	14	14	X	x	NN
cord-278081-tk7vn1v1	14	15	can	can	MD
cord-278081-tk7vn1v1	14	16	compete	compete	VB
cord-278081-tk7vn1v1	14	17	with	with	IN
cord-278081-tk7vn1v1	14	18	RNA	RNA	NNP
cord-278081-tk7vn1v1	14	19	transcripts	transcript	NNS
cord-278081-tk7vn1v1	14	20	containing	contain	VBG
cord-278081-tk7vn1v1	14	21	intronic	intronic	NNP
cord-278081-tk7vn1v1	14	22	Alu	Alu	NNP
cord-278081-tk7vn1v1	14	23	sequences	sequence	NNS
cord-278081-tk7vn1v1	14	24	that	that	WDT
cord-278081-tk7vn1v1	14	25	normally	normally	RB
cord-278081-tk7vn1v1	14	26	maintain	maintain	VBP
cord-278081-tk7vn1v1	14	27	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	14	28	structural	structural	JJ
cord-278081-tk7vn1v1	14	29	integrity	integrity	NN
cord-278081-tk7vn1v1	14	30	.	.	.
cord-278081-tk7vn1v1	15	1	Such	such	JJ
cord-278081-tk7vn1v1	15	2	disruption	disruption	NN
cord-278081-tk7vn1v1	15	3	of	of	IN
cord-278081-tk7vn1v1	15	4	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	15	5	activity	activity	NN
cord-278081-tk7vn1v1	15	6	can	can	MD
cord-278081-tk7vn1v1	15	7	lead	lead	VB
cord-278081-tk7vn1v1	15	8	to	to	IN
cord-278081-tk7vn1v1	15	9	misfolded	misfolded	JJ
cord-278081-tk7vn1v1	15	10	RNAs	rna	NNS
cord-278081-tk7vn1v1	15	11	,	,	,
cord-278081-tk7vn1v1	15	12	misassembled	misassemble	VBN
cord-278081-tk7vn1v1	15	13	ribonucleoprotein	ribonucleoprotein	NN
cord-278081-tk7vn1v1	15	14	complexes	complex	NNS
cord-278081-tk7vn1v1	15	15	,	,	,
cord-278081-tk7vn1v1	15	16	and	and	CC
cord-278081-tk7vn1v1	15	17	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	15	18	of	of	IN
cord-278081-tk7vn1v1	15	19	the	the	DT
cord-278081-tk7vn1v1	15	20	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	15	21	.	.	.
cord-278081-tk7vn1v1	16	1	Many	many	JJ
cord-278081-tk7vn1v1	16	2	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	16	3	in	in	IN
cord-278081-tk7vn1v1	16	4	lupus	lupus	NN
cord-278081-tk7vn1v1	16	5	are	be	VBP
cord-278081-tk7vn1v1	16	6	,	,	,
cord-278081-tk7vn1v1	16	7	at	at	IN
cord-278081-tk7vn1v1	16	8	least	least	JJS
cord-278081-tk7vn1v1	16	9	transiently	transiently	RB
cord-278081-tk7vn1v1	16	10	,	,	,
cord-278081-tk7vn1v1	16	11	components	component	NNS
cord-278081-tk7vn1v1	16	12	of	of	IN
cord-278081-tk7vn1v1	16	13	the	the	DT
cord-278081-tk7vn1v1	16	14	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	16	15	.	.	.
cord-278081-tk7vn1v1	17	1	Considering	consider	VBG
cord-278081-tk7vn1v1	17	2	these	these	DT
cord-278081-tk7vn1v1	17	3	effects	effect	NNS
cord-278081-tk7vn1v1	17	4	of	of	IN
cord-278081-tk7vn1v1	17	5	viruses	virus	NNS
cord-278081-tk7vn1v1	17	6	,	,	,
cord-278081-tk7vn1v1	17	7	the	the	DT
cord-278081-tk7vn1v1	17	8	“	"	``
cord-278081-tk7vn1v1	17	9	X	x	NN
cord-278081-tk7vn1v1	17	10	chromosome	chromosome	NN
cord-278081-tk7vn1v1	17	11	–	–	:
cord-278081-tk7vn1v1	17	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	17	13	nexus	nexus	NN
cord-278081-tk7vn1v1	17	14	”	"	''
cord-278081-tk7vn1v1	17	15	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	17	16	,	,	,
cord-278081-tk7vn1v1	17	17	which	which	WDT
cord-278081-tk7vn1v1	17	18	proposed	propose	VBD
cord-278081-tk7vn1v1	17	19	disruption	disruption	NN
cord-278081-tk7vn1v1	17	20	of	of	IN
cord-278081-tk7vn1v1	17	21	the	the	DT
cord-278081-tk7vn1v1	17	22	inactive	inactive	JJ
cord-278081-tk7vn1v1	17	23	X	X	NNS
cord-278081-tk7vn1v1	17	24	by	by	IN
cord-278081-tk7vn1v1	17	25	the	the	DT
cord-278081-tk7vn1v1	17	26	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	17	27	during	during	IN
cord-278081-tk7vn1v1	17	28	stress	stress	NN
cord-278081-tk7vn1v1	17	29	,	,	,
cord-278081-tk7vn1v1	17	30	is	be	VBZ
cord-278081-tk7vn1v1	17	31	now	now	RB
cord-278081-tk7vn1v1	17	32	expanded	expand	VBN
cord-278081-tk7vn1v1	17	33	here	here	RB
cord-278081-tk7vn1v1	17	34	to	to	TO
cord-278081-tk7vn1v1	17	35	propose	propose	VB
cord-278081-tk7vn1v1	17	36	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	17	37	disruption	disruption	NN
cord-278081-tk7vn1v1	17	38	of	of	IN
cord-278081-tk7vn1v1	17	39	the	the	DT
cord-278081-tk7vn1v1	17	40	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	17	41	by	by	IN
cord-278081-tk7vn1v1	17	42	previously	previously	RB
cord-278081-tk7vn1v1	17	43	sequestered	sequester	VBN
cord-278081-tk7vn1v1	17	44	Alu	Alu	NNP
cord-278081-tk7vn1v1	17	45	elements	element	NNS
cord-278081-tk7vn1v1	17	46	,	,	,
cord-278081-tk7vn1v1	17	47	which	which	WDT
cord-278081-tk7vn1v1	17	48	can	can	MD
cord-278081-tk7vn1v1	17	49	fragment	fragment	VB
cord-278081-tk7vn1v1	17	50	the	the	DT
cord-278081-tk7vn1v1	17	51	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	17	52	,	,	,
cord-278081-tk7vn1v1	17	53	leading	lead	VBG
cord-278081-tk7vn1v1	17	54	to	to	IN
cord-278081-tk7vn1v1	17	55	generation	generation	NN
cord-278081-tk7vn1v1	17	56	of	of	IN
cord-278081-tk7vn1v1	17	57	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	17	58	.	.	.
cord-278081-tk7vn1v1	18	1	Previously	previously	RB
cord-278081-tk7vn1v1	18	2	,	,	,
cord-278081-tk7vn1v1	18	3	we	-PRON-	PRP
cord-278081-tk7vn1v1	18	4	presented	present	VBD
cord-278081-tk7vn1v1	18	5	the	the	DT
cord-278081-tk7vn1v1	18	6	"	"	``
cord-278081-tk7vn1v1	18	7	X	x	NN
cord-278081-tk7vn1v1	18	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	18	9	-	-	HYPH
cord-278081-tk7vn1v1	18	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	18	11	nexus	nexus	NN
cord-278081-tk7vn1v1	18	12	"	"	''
cord-278081-tk7vn1v1	18	13	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	18	14	(	(	-LRB-
cord-278081-tk7vn1v1	18	15	1	1	CD
cord-278081-tk7vn1v1	18	16	)	)	-RRB-
cord-278081-tk7vn1v1	18	17	(	(	-LRB-
cord-278081-tk7vn1v1	18	18	2	2	LS
cord-278081-tk7vn1v1	18	19	)	)	-RRB-
cord-278081-tk7vn1v1	18	20	(	(	-LRB-
cord-278081-tk7vn1v1	18	21	3	3	CD
cord-278081-tk7vn1v1	18	22	)	)	-RRB-
cord-278081-tk7vn1v1	18	23	.	.	.
cord-278081-tk7vn1v1	19	1	In	in	IN
cord-278081-tk7vn1v1	19	2	the	the	DT
cord-278081-tk7vn1v1	19	3	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	19	4	it	-PRON-	PRP
cord-278081-tk7vn1v1	19	5	was	be	VBD
cord-278081-tk7vn1v1	19	6	proposed	propose	VBN
cord-278081-tk7vn1v1	19	7	that	that	DT
cord-278081-tk7vn1v1	19	8	enlargement	enlargement	NN
cord-278081-tk7vn1v1	19	9	of	of	IN
cord-278081-tk7vn1v1	19	10	the	the	DT
cord-278081-tk7vn1v1	19	11	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	19	12	in	in	IN
cord-278081-tk7vn1v1	19	13	response	response	NN
cord-278081-tk7vn1v1	19	14	to	to	IN
cord-278081-tk7vn1v1	19	15	cellular	cellular	JJ
cord-278081-tk7vn1v1	19	16	stress	stress	NN
cord-278081-tk7vn1v1	19	17	could	could	MD
cord-278081-tk7vn1v1	19	18	disrupt	disrupt	VB
cord-278081-tk7vn1v1	19	19	neighboring	neighboring	NN
cord-278081-tk7vn1v1	19	20	chromatin	chromatin	NN
cord-278081-tk7vn1v1	19	21	,	,	,
cord-278081-tk7vn1v1	19	22	such	such	JJ
cord-278081-tk7vn1v1	19	23	as	as	IN
cord-278081-tk7vn1v1	19	24	the	the	DT
cord-278081-tk7vn1v1	19	25	inactive	inactive	JJ
cord-278081-tk7vn1v1	19	26	X	x	NN
cord-278081-tk7vn1v1	19	27	chromosome	chromosome	NN
cord-278081-tk7vn1v1	19	28	.	.	.
cord-278081-tk7vn1v1	20	1	As	as	IN
cord-278081-tk7vn1v1	20	2	a	a	DT
cord-278081-tk7vn1v1	20	3	result	result	NN
cord-278081-tk7vn1v1	20	4	,	,	,
cord-278081-tk7vn1v1	20	5	sequestered	sequester	VBN
cord-278081-tk7vn1v1	20	6	alleles	allele	NNS
cord-278081-tk7vn1v1	20	7	(	(	-LRB-
cord-278081-tk7vn1v1	20	8	e.g.	e.g.	RB
cord-278081-tk7vn1v1	20	9	,	,	,
cord-278081-tk7vn1v1	20	10	polyamine	polyamine	NN
cord-278081-tk7vn1v1	20	11	genes	gene	NNS
cord-278081-tk7vn1v1	20	12	on	on	IN
cord-278081-tk7vn1v1	20	13	the	the	DT
cord-278081-tk7vn1v1	20	14	inactive	inactive	JJ
cord-278081-tk7vn1v1	20	15	X	X	NNS
cord-278081-tk7vn1v1	20	16	)	)	-RRB-
cord-278081-tk7vn1v1	20	17	,	,	,
cord-278081-tk7vn1v1	20	18	elements	element	NNS
cord-278081-tk7vn1v1	20	19	(	(	-LRB-
cord-278081-tk7vn1v1	20	20	e.g.	e.g.	RB
cord-278081-tk7vn1v1	20	21	,	,	,
cord-278081-tk7vn1v1	20	22	Alu	Alu	NNP
cord-278081-tk7vn1v1	20	23	elements	element	NNS
cord-278081-tk7vn1v1	20	24	)	)	-RRB-
cord-278081-tk7vn1v1	20	25	,	,	,
cord-278081-tk7vn1v1	20	26	and	and	CC
cord-278081-tk7vn1v1	20	27	viruses	virus	NNS
cord-278081-tk7vn1v1	20	28	could	could	MD
cord-278081-tk7vn1v1	20	29	be	be	VB
cord-278081-tk7vn1v1	20	30	opened	open	VBN
cord-278081-tk7vn1v1	20	31	for	for	IN
cord-278081-tk7vn1v1	20	32	transcription	transcription	NN
cord-278081-tk7vn1v1	20	33	.	.	.
cord-278081-tk7vn1v1	21	1	This	this	DT
cord-278081-tk7vn1v1	21	2	could	could	MD
cord-278081-tk7vn1v1	21	3	lead	lead	VB
cord-278081-tk7vn1v1	21	4	to	to	IN
cord-278081-tk7vn1v1	21	5	eventual	eventual	JJ
cord-278081-tk7vn1v1	21	6	creation	creation	NN
cord-278081-tk7vn1v1	21	7	of	of	IN
cord-278081-tk7vn1v1	21	8	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	21	9	due	due	IN
cord-278081-tk7vn1v1	21	10	to	to	IN
cord-278081-tk7vn1v1	21	11	overexpression	overexpression	NN
cord-278081-tk7vn1v1	21	12	of	of	IN
cord-278081-tk7vn1v1	21	13	genes	gene	NNS
cord-278081-tk7vn1v1	21	14	and	and	CC
cord-278081-tk7vn1v1	21	15	elements	element	NNS
cord-278081-tk7vn1v1	21	16	from	from	IN
cord-278081-tk7vn1v1	21	17	both	both	CC
cord-278081-tk7vn1v1	21	18	the	the	DT
cord-278081-tk7vn1v1	21	19	previously	previously	RB
cord-278081-tk7vn1v1	21	20	active	active	JJ
cord-278081-tk7vn1v1	21	21	chromatin	chromatin	NN
cord-278081-tk7vn1v1	21	22	and	and	CC
cord-278081-tk7vn1v1	21	23	the	the	DT
cord-278081-tk7vn1v1	21	24	,	,	,
cord-278081-tk7vn1v1	21	25	now	now	RB
cord-278081-tk7vn1v1	21	26	,	,	,
cord-278081-tk7vn1v1	21	27	reactivated	reactivate	VBN
cord-278081-tk7vn1v1	21	28	chromatin	chromatin	NN
cord-278081-tk7vn1v1	21	29	.	.	.
cord-278081-tk7vn1v1	22	1	Here	here	RB
cord-278081-tk7vn1v1	22	2	is	be	VBZ
cord-278081-tk7vn1v1	22	3	presented	present	VBN
cord-278081-tk7vn1v1	22	4	new	new	JJ
cord-278081-tk7vn1v1	22	5	details	detail	NNS
cord-278081-tk7vn1v1	22	6	to	to	IN
cord-278081-tk7vn1v1	22	7	the	the	DT
cord-278081-tk7vn1v1	22	8	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	22	9	,	,	,
cord-278081-tk7vn1v1	22	10	explaining	explain	VBG
cord-278081-tk7vn1v1	22	11	how	how	WRB
cord-278081-tk7vn1v1	22	12	the	the	DT
cord-278081-tk7vn1v1	22	13	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	22	14	chromatin	chromatin	NN
cord-278081-tk7vn1v1	22	15	can	can	MD
cord-278081-tk7vn1v1	22	16	lead	lead	VB
cord-278081-tk7vn1v1	22	17	to	to	IN
cord-278081-tk7vn1v1	22	18	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	22	19	disruption	disruption	NN
cord-278081-tk7vn1v1	22	20	of	of	IN
cord-278081-tk7vn1v1	22	21	the	the	DT
cord-278081-tk7vn1v1	22	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	22	23	,	,	,
cord-278081-tk7vn1v1	22	24	even	even	RB
cord-278081-tk7vn1v1	22	25	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	22	26	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	22	27	,	,	,
cord-278081-tk7vn1v1	22	28	which	which	WDT
cord-278081-tk7vn1v1	22	29	results	result	VBZ
cord-278081-tk7vn1v1	22	30	in	in	IN
cord-278081-tk7vn1v1	22	31	ineffective	ineffective	JJ
cord-278081-tk7vn1v1	22	32	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	22	33	functioning	function	VBG
cord-278081-tk7vn1v1	22	34	,	,	,
cord-278081-tk7vn1v1	22	35	misfolded	misfolded	JJ
cord-278081-tk7vn1v1	22	36	RNAs	rna	NNS
cord-278081-tk7vn1v1	22	37	,	,	,
cord-278081-tk7vn1v1	22	38	misassembled	misassemble	VBN
cord-278081-tk7vn1v1	22	39	or	or	CC
cord-278081-tk7vn1v1	22	40	incompletely	incompletely	RB
cord-278081-tk7vn1v1	22	41	assembled	assemble	VBN
cord-278081-tk7vn1v1	22	42	ribonucleoprotein	ribonucleoprotein	NN
cord-278081-tk7vn1v1	22	43	(	(	-LRB-
cord-278081-tk7vn1v1	22	44	RNP	RNP	NNP
cord-278081-tk7vn1v1	22	45	)	)	-RRB-
cord-278081-tk7vn1v1	22	46	complexes	complex	NNS
cord-278081-tk7vn1v1	22	47	,	,	,
cord-278081-tk7vn1v1	22	48	and	and	CC
cord-278081-tk7vn1v1	22	49	stabilization	stabilization	NN
cord-278081-tk7vn1v1	22	50	of	of	IN
cord-278081-tk7vn1v1	22	51	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	22	52	components	component	NNS
cord-278081-tk7vn1v1	22	53	in	in	IN
cord-278081-tk7vn1v1	22	54	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	22	55	conformations	conformation	NNS
cord-278081-tk7vn1v1	22	56	.	.	.
cord-278081-tk7vn1v1	23	1	Many	many	JJ
cord-278081-tk7vn1v1	23	2	of	of	IN
cord-278081-tk7vn1v1	23	3	the	the	DT
cord-278081-tk7vn1v1	23	4	major	major	JJ
cord-278081-tk7vn1v1	23	5	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	23	6	in	in	IN
cord-278081-tk7vn1v1	23	7	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	23	8	diseases	disease	NNS
cord-278081-tk7vn1v1	23	9	like	like	IN
cord-278081-tk7vn1v1	23	10	systemic	systemic	JJ
cord-278081-tk7vn1v1	23	11	lupus	lupus	NN
cord-278081-tk7vn1v1	23	12	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	23	13	(	(	-LRB-
cord-278081-tk7vn1v1	23	14	SLE	SLE	NNP
cord-278081-tk7vn1v1	23	15	)	)	-RRB-
cord-278081-tk7vn1v1	23	16	are	be	VBP
cord-278081-tk7vn1v1	23	17	,	,	,
cord-278081-tk7vn1v1	23	18	at	at	IN
cord-278081-tk7vn1v1	23	19	least	least	JJS
cord-278081-tk7vn1v1	23	20	transiently	transiently	RB
cord-278081-tk7vn1v1	23	21	,	,	,
cord-278081-tk7vn1v1	23	22	components	component	NNS
cord-278081-tk7vn1v1	23	23	of	of	IN
cord-278081-tk7vn1v1	23	24	the	the	DT
cord-278081-tk7vn1v1	23	25	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	23	26	(	(	-LRB-
cord-278081-tk7vn1v1	23	27	e.g.	e.g.	RB
cord-278081-tk7vn1v1	23	28	,	,	,
cord-278081-tk7vn1v1	23	29	splicosome	splicosome	NNP
cord-278081-tk7vn1v1	23	30	subunits	subunit	NNS
cord-278081-tk7vn1v1	23	31	)	)	-RRB-
cord-278081-tk7vn1v1	23	32	.	.	.
cord-278081-tk7vn1v1	24	1	Among	among	IN
cord-278081-tk7vn1v1	24	2	the	the	DT
cord-278081-tk7vn1v1	24	3	factors	factor	NNS
cord-278081-tk7vn1v1	24	4	that	that	WDT
cord-278081-tk7vn1v1	24	5	could	could	MD
cord-278081-tk7vn1v1	24	6	cause	cause	VB
cord-278081-tk7vn1v1	24	7	extraordinary	extraordinary	JJ
cord-278081-tk7vn1v1	24	8	cellular	cellular	JJ
cord-278081-tk7vn1v1	24	9	stress	stress	NN
cord-278081-tk7vn1v1	24	10	,	,	,
cord-278081-tk7vn1v1	24	11	viruses	virus	NNS
cord-278081-tk7vn1v1	24	12	are	be	VBP
cord-278081-tk7vn1v1	24	13	highly	highly	RB
cord-278081-tk7vn1v1	24	14	suspected	suspect	VBN
cord-278081-tk7vn1v1	24	15	of	of	IN
cord-278081-tk7vn1v1	24	16	causing	cause	VBG
cord-278081-tk7vn1v1	24	17	such	such	JJ
cord-278081-tk7vn1v1	24	18	disruption	disruption	NN
cord-278081-tk7vn1v1	24	19	in	in	IN
cord-278081-tk7vn1v1	24	20	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	24	21	diseases	disease	NNS
cord-278081-tk7vn1v1	24	22	.	.	.
cord-278081-tk7vn1v1	25	1	Exposomics	Exposomics	NNP
cord-278081-tk7vn1v1	25	2	is	be	VBZ
cord-278081-tk7vn1v1	25	3	the	the	DT
cord-278081-tk7vn1v1	25	4	study	study	NN
cord-278081-tk7vn1v1	25	5	of	of	IN
cord-278081-tk7vn1v1	25	6	all	all	DT
cord-278081-tk7vn1v1	25	7	environmental	environmental	JJ
cord-278081-tk7vn1v1	25	8	factors	factor	NNS
cord-278081-tk7vn1v1	25	9	which	which	WDT
cord-278081-tk7vn1v1	25	10	a	a	DT
cord-278081-tk7vn1v1	25	11	person	person	NN
cord-278081-tk7vn1v1	25	12	may	may	MD
cord-278081-tk7vn1v1	25	13	encounter	encounter	VB
cord-278081-tk7vn1v1	25	14	during	during	IN
cord-278081-tk7vn1v1	25	15	their	-PRON-	PRP$
cord-278081-tk7vn1v1	25	16	lifetime	lifetime	NN
cord-278081-tk7vn1v1	25	17	,	,	,
cord-278081-tk7vn1v1	25	18	even	even	RB
cord-278081-tk7vn1v1	25	19	including	include	VBG
cord-278081-tk7vn1v1	25	20	prenatal	prenatal	JJ
cord-278081-tk7vn1v1	25	21	exposure	exposure	NN
cord-278081-tk7vn1v1	25	22	.	.	.
cord-278081-tk7vn1v1	26	1	These	these	DT
cord-278081-tk7vn1v1	26	2	environmental	environmental	JJ
cord-278081-tk7vn1v1	26	3	factors	factor	NNS
cord-278081-tk7vn1v1	26	4	in	in	IN
cord-278081-tk7vn1v1	26	5	the	the	DT
cord-278081-tk7vn1v1	26	6	exposome	exposome	NN
cord-278081-tk7vn1v1	26	7	can	can	MD
cord-278081-tk7vn1v1	26	8	include	include	VB
cord-278081-tk7vn1v1	26	9	components	component	NNS
cord-278081-tk7vn1v1	26	10	of	of	IN
cord-278081-tk7vn1v1	26	11	the	the	DT
cord-278081-tk7vn1v1	26	12	diet	diet	NN
cord-278081-tk7vn1v1	26	13	,	,	,
cord-278081-tk7vn1v1	26	14	gut	gut	NN
cord-278081-tk7vn1v1	26	15	microbiota	microbiota	NN
cord-278081-tk7vn1v1	26	16	,	,	,
cord-278081-tk7vn1v1	26	17	chemicals	chemical	NNS
cord-278081-tk7vn1v1	26	18	,	,	,
cord-278081-tk7vn1v1	26	19	air	air	NN
cord-278081-tk7vn1v1	26	20	pollutants	pollutant	NNS
cord-278081-tk7vn1v1	26	21	,	,	,
cord-278081-tk7vn1v1	26	22	heavy	heavy	JJ
cord-278081-tk7vn1v1	26	23	metals	metal	NNS
cord-278081-tk7vn1v1	26	24	,	,	,
cord-278081-tk7vn1v1	26	25	and	and	CC
cord-278081-tk7vn1v1	26	26	infectious	infectious	JJ
cord-278081-tk7vn1v1	26	27	agents	agent	NNS
cord-278081-tk7vn1v1	26	28	.	.	.
cord-278081-tk7vn1v1	27	1	These	these	DT
cord-278081-tk7vn1v1	27	2	factors	factor	NNS
cord-278081-tk7vn1v1	27	3	can	can	MD
cord-278081-tk7vn1v1	27	4	cause	cause	VB
cord-278081-tk7vn1v1	27	5	cellular	cellular	JJ
cord-278081-tk7vn1v1	27	6	stress	stress	NN
cord-278081-tk7vn1v1	27	7	and	and	CC
cord-278081-tk7vn1v1	27	8	can	can	MD
cord-278081-tk7vn1v1	27	9	have	have	VB
cord-278081-tk7vn1v1	27	10	a	a	DT
cord-278081-tk7vn1v1	27	11	cumulative	cumulative	JJ
cord-278081-tk7vn1v1	27	12	effect	effect	NN
cord-278081-tk7vn1v1	27	13	in	in	IN
cord-278081-tk7vn1v1	27	14	cells	cell	NNS
cord-278081-tk7vn1v1	27	15	through	through	IN
cord-278081-tk7vn1v1	27	16	accumulation	accumulation	NN
cord-278081-tk7vn1v1	27	17	of	of	IN
cord-278081-tk7vn1v1	27	18	genetic	genetic	JJ
cord-278081-tk7vn1v1	27	19	damage	damage	NN
cord-278081-tk7vn1v1	27	20	and/or	and/or	CC
cord-278081-tk7vn1v1	27	21	disruption	disruption	NN
cord-278081-tk7vn1v1	27	22	of	of	IN
cord-278081-tk7vn1v1	27	23	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	27	24	control	control	NN
cord-278081-tk7vn1v1	27	25	,	,	,
cord-278081-tk7vn1v1	27	26	especially	especially	RB
cord-278081-tk7vn1v1	27	27	in	in	IN
cord-278081-tk7vn1v1	27	28	genetically	genetically	RB
cord-278081-tk7vn1v1	27	29	predisposed	predispose	VBN
cord-278081-tk7vn1v1	27	30	individuals	individual	NNS
cord-278081-tk7vn1v1	27	31	,	,	,
cord-278081-tk7vn1v1	27	32	that	that	WDT
cord-278081-tk7vn1v1	27	33	establishes	establish	VBZ
cord-278081-tk7vn1v1	27	34	the	the	DT
cord-278081-tk7vn1v1	27	35	conditions	condition	NNS
cord-278081-tk7vn1v1	27	36	for	for	IN
cord-278081-tk7vn1v1	27	37	eventual	eventual	JJ
cord-278081-tk7vn1v1	27	38	manifestation	manifestation	NN
cord-278081-tk7vn1v1	27	39	and	and	CC
cord-278081-tk7vn1v1	27	40	progression	progression	NN
cord-278081-tk7vn1v1	27	41	of	of	IN
cord-278081-tk7vn1v1	27	42	an	an	DT
cord-278081-tk7vn1v1	27	43	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	27	44	disease	disease	NN
cord-278081-tk7vn1v1	27	45	.	.	.
cord-278081-tk7vn1v1	28	1	Within	within	IN
cord-278081-tk7vn1v1	28	2	the	the	DT
cord-278081-tk7vn1v1	28	3	exposome	exposome	NN
cord-278081-tk7vn1v1	28	4	is	be	VBZ
cord-278081-tk7vn1v1	28	5	the	the	DT
cord-278081-tk7vn1v1	28	6	infectome	infectome	NN
cord-278081-tk7vn1v1	28	7	which	which	WDT
cord-278081-tk7vn1v1	28	8	is	be	VBZ
cord-278081-tk7vn1v1	28	9	the	the	DT
cord-278081-tk7vn1v1	28	10	collection	collection	NN
cord-278081-tk7vn1v1	28	11	of	of	IN
cord-278081-tk7vn1v1	28	12	pathogens	pathogen	NNS
cord-278081-tk7vn1v1	28	13	that	that	WDT
cord-278081-tk7vn1v1	28	14	may	may	MD
cord-278081-tk7vn1v1	28	15	contribute	contribute	VB
cord-278081-tk7vn1v1	28	16	to	to	IN
cord-278081-tk7vn1v1	28	17	an	an	DT
cord-278081-tk7vn1v1	28	18	individual	individual	NN
cord-278081-tk7vn1v1	28	19	's	's	POS
cord-278081-tk7vn1v1	28	20	onset	onset	NN
cord-278081-tk7vn1v1	28	21	and	and	CC
cord-278081-tk7vn1v1	28	22	progression	progression	NN
cord-278081-tk7vn1v1	28	23	of	of	IN
cord-278081-tk7vn1v1	28	24	an	an	DT
cord-278081-tk7vn1v1	28	25	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	28	26	disease	disease	NN
cord-278081-tk7vn1v1	28	27	(	(	-LRB-
cord-278081-tk7vn1v1	28	28	4	4	CD
cord-278081-tk7vn1v1	28	29	)	)	-RRB-
cord-278081-tk7vn1v1	28	30	.	.	.
cord-278081-tk7vn1v1	29	1	This	this	DT
cord-278081-tk7vn1v1	29	2	can	can	MD
cord-278081-tk7vn1v1	29	3	be	be	VB
cord-278081-tk7vn1v1	29	4	complicated	complicate	VBN
cord-278081-tk7vn1v1	29	5	by	by	IN
cord-278081-tk7vn1v1	29	6	the	the	DT
cord-278081-tk7vn1v1	29	7	latency	latency	NN
cord-278081-tk7vn1v1	29	8	of	of	IN
cord-278081-tk7vn1v1	29	9	some	some	DT
cord-278081-tk7vn1v1	29	10	pathogens	pathogen	NNS
cord-278081-tk7vn1v1	29	11	and	and	CC
cord-278081-tk7vn1v1	29	12	the	the	DT
cord-278081-tk7vn1v1	29	13	synergistic	synergistic	JJ
cord-278081-tk7vn1v1	29	14	effects	effect	NNS
cord-278081-tk7vn1v1	29	15	of	of	IN
cord-278081-tk7vn1v1	29	16	multiple	multiple	JJ
cord-278081-tk7vn1v1	29	17	pathogens	pathogen	NNS
cord-278081-tk7vn1v1	29	18	.	.	.
cord-278081-tk7vn1v1	30	1	However	however	RB
cord-278081-tk7vn1v1	30	2	,	,	,
cord-278081-tk7vn1v1	30	3	unless	unless	IN
cord-278081-tk7vn1v1	30	4	one	one	CD
cord-278081-tk7vn1v1	30	5	is	be	VBZ
cord-278081-tk7vn1v1	30	6	looking	look	VBG
cord-278081-tk7vn1v1	30	7	for	for	IN
cord-278081-tk7vn1v1	30	8	pathogen	pathogen	NN
cord-278081-tk7vn1v1	30	9	antigens	antigen	NNS
cord-278081-tk7vn1v1	30	10	,	,	,
cord-278081-tk7vn1v1	30	11	the	the	DT
cord-278081-tk7vn1v1	30	12	specific	specific	JJ
cord-278081-tk7vn1v1	30	13	pathogen	pathogen	NN
cord-278081-tk7vn1v1	30	14	and	and	CC
cord-278081-tk7vn1v1	30	15	its	-PRON-	PRP$
cord-278081-tk7vn1v1	30	16	effect	effect	NN
cord-278081-tk7vn1v1	30	17	on	on	IN
cord-278081-tk7vn1v1	30	18	the	the	DT
cord-278081-tk7vn1v1	30	19	immune	immune	JJ
cord-278081-tk7vn1v1	30	20	system	system	NN
cord-278081-tk7vn1v1	30	21	may	may	MD
cord-278081-tk7vn1v1	30	22	be	be	VB
cord-278081-tk7vn1v1	30	23	masked	mask	VBN
cord-278081-tk7vn1v1	30	24	by	by	IN
cord-278081-tk7vn1v1	30	25	a	a	DT
cord-278081-tk7vn1v1	30	26	larger	large	JJR
cord-278081-tk7vn1v1	30	27	response	response	NN
cord-278081-tk7vn1v1	30	28	to	to	IN
cord-278081-tk7vn1v1	30	29	more	more	RBR
cord-278081-tk7vn1v1	30	30	abundant	abundant	JJ
cord-278081-tk7vn1v1	30	31	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	30	32	some	some	DT
cord-278081-tk7vn1v1	30	33	of	of	IN
cord-278081-tk7vn1v1	30	34	which	which	WDT
cord-278081-tk7vn1v1	30	35	the	the	DT
cord-278081-tk7vn1v1	30	36	pathogen	pathogen	NN
cord-278081-tk7vn1v1	30	37	's	's	POS
cord-278081-tk7vn1v1	30	38	antigens	antigen	NNS
cord-278081-tk7vn1v1	30	39	may	may	MD
cord-278081-tk7vn1v1	30	40	mimic	mimic	VB
cord-278081-tk7vn1v1	30	41	.	.	.
cord-278081-tk7vn1v1	31	1	In	in	IN
cord-278081-tk7vn1v1	31	2	addition	addition	NN
cord-278081-tk7vn1v1	31	3	,	,	,
cord-278081-tk7vn1v1	31	4	it	-PRON-	PRP
cord-278081-tk7vn1v1	31	5	has	have	VBZ
cord-278081-tk7vn1v1	31	6	been	be	VBN
cord-278081-tk7vn1v1	31	7	difficult	difficult	JJ
cord-278081-tk7vn1v1	31	8	to	to	TO
cord-278081-tk7vn1v1	31	9	prove	prove	VB
cord-278081-tk7vn1v1	31	10	these	these	DT
cord-278081-tk7vn1v1	31	11	associations	association	NNS
cord-278081-tk7vn1v1	31	12	since	since	IN
cord-278081-tk7vn1v1	31	13	,	,	,
cord-278081-tk7vn1v1	31	14	in	in	IN
cord-278081-tk7vn1v1	31	15	the	the	DT
cord-278081-tk7vn1v1	31	16	case	case	NN
cord-278081-tk7vn1v1	31	17	of	of	IN
cord-278081-tk7vn1v1	31	18	viruses	virus	NNS
cord-278081-tk7vn1v1	31	19	,	,	,
cord-278081-tk7vn1v1	31	20	many	many	JJ
cord-278081-tk7vn1v1	31	21	viruses	virus	NNS
cord-278081-tk7vn1v1	31	22	can	can	MD
cord-278081-tk7vn1v1	31	23	establish	establish	VB
cord-278081-tk7vn1v1	31	24	latent	latent	JJ
cord-278081-tk7vn1v1	31	25	infections	infection	NNS
cord-278081-tk7vn1v1	31	26	but	but	CC
cord-278081-tk7vn1v1	31	27	the	the	DT
cord-278081-tk7vn1v1	31	28	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	31	29	disease	disease	NN
cord-278081-tk7vn1v1	31	30	may	may	MD
cord-278081-tk7vn1v1	31	31	not	not	RB
cord-278081-tk7vn1v1	31	32	manifest	manifest	VB
cord-278081-tk7vn1v1	31	33	itself	-PRON-	PRP
cord-278081-tk7vn1v1	31	34	until	until	IN
cord-278081-tk7vn1v1	31	35	several	several	JJ
cord-278081-tk7vn1v1	31	36	years	year	NNS
cord-278081-tk7vn1v1	31	37	after	after	IN
cord-278081-tk7vn1v1	31	38	the	the	DT
cord-278081-tk7vn1v1	31	39	initial	initial	JJ
cord-278081-tk7vn1v1	31	40	infection	infection	NN
cord-278081-tk7vn1v1	31	41	,	,	,
cord-278081-tk7vn1v1	31	42	thus	thus	RB
cord-278081-tk7vn1v1	31	43	clouding	cloud	VBG
cord-278081-tk7vn1v1	31	44	the	the	DT
cord-278081-tk7vn1v1	31	45	true	true	JJ
cord-278081-tk7vn1v1	31	46	extent	extent	NN
cord-278081-tk7vn1v1	31	47	of	of	IN
cord-278081-tk7vn1v1	31	48	their	-PRON-	PRP$
cord-278081-tk7vn1v1	31	49	association	association	NN
cord-278081-tk7vn1v1	31	50	.	.	.
cord-278081-tk7vn1v1	32	1	For	for	IN
cord-278081-tk7vn1v1	32	2	example	example	NN
cord-278081-tk7vn1v1	32	3	,	,	,
cord-278081-tk7vn1v1	32	4	a	a	DT
cord-278081-tk7vn1v1	32	5	mononucleosis	mononucleosis	NN
cord-278081-tk7vn1v1	32	6	infection	infection	NN
cord-278081-tk7vn1v1	32	7	,	,	,
cord-278081-tk7vn1v1	32	8	a.k.a	a.k.a	JJ
cord-278081-tk7vn1v1	32	9	.	.	.
cord-278081-tk7vn1v1	32	10	the	the	DT
cord-278081-tk7vn1v1	32	11	"	"	``
cord-278081-tk7vn1v1	32	12	kissing	kiss	VBG
cord-278081-tk7vn1v1	32	13	disease	disease	NN
cord-278081-tk7vn1v1	32	14	,	,	,
cord-278081-tk7vn1v1	32	15	"	"	''
cord-278081-tk7vn1v1	32	16	which	which	WDT
cord-278081-tk7vn1v1	32	17	involves	involve	VBZ
cord-278081-tk7vn1v1	32	18	the	the	DT
cord-278081-tk7vn1v1	32	19	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	32	20	-	-	HYPH
cord-278081-tk7vn1v1	32	21	Barr	Barr	NNP
cord-278081-tk7vn1v1	32	22	virus	virus	NN
cord-278081-tk7vn1v1	32	23	(	(	-LRB-
cord-278081-tk7vn1v1	32	24	EBV	EBV	NNP
cord-278081-tk7vn1v1	32	25	)	)	-RRB-
cord-278081-tk7vn1v1	32	26	,	,	,
cord-278081-tk7vn1v1	32	27	increases	increase	VBZ
cord-278081-tk7vn1v1	32	28	the	the	DT
cord-278081-tk7vn1v1	32	29	risk	risk	NN
cord-278081-tk7vn1v1	32	30	for	for	IN
cord-278081-tk7vn1v1	32	31	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	32	32	appearance	appearance	NN
cord-278081-tk7vn1v1	32	33	of	of	IN
cord-278081-tk7vn1v1	32	34	multiple	multiple	JJ
cord-278081-tk7vn1v1	32	35	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	32	36	(	(	-LRB-
cord-278081-tk7vn1v1	32	37	MS	MS	NNP
cord-278081-tk7vn1v1	32	38	)	)	-RRB-
cord-278081-tk7vn1v1	32	39	but	but	CC
cord-278081-tk7vn1v1	32	40	manifestation	manifestation	NN
cord-278081-tk7vn1v1	32	41	of	of	IN
cord-278081-tk7vn1v1	32	42	the	the	DT
cord-278081-tk7vn1v1	32	43	MS	MS	NNP
cord-278081-tk7vn1v1	32	44	might	may	MD
cord-278081-tk7vn1v1	32	45	not	not	RB
cord-278081-tk7vn1v1	32	46	occur	occur	VB
cord-278081-tk7vn1v1	32	47	until	until	IN
cord-278081-tk7vn1v1	32	48	as	as	RB
cord-278081-tk7vn1v1	32	49	long	long	JJ
cord-278081-tk7vn1v1	32	50	as	as	IN
cord-278081-tk7vn1v1	32	51	30	30	CD
cord-278081-tk7vn1v1	32	52	years	year	NNS
cord-278081-tk7vn1v1	32	53	after	after	IN
cord-278081-tk7vn1v1	32	54	the	the	DT
cord-278081-tk7vn1v1	32	55	mononucleosis	mononucleosis	NNP
cord-278081-tk7vn1v1	32	56	episode	episode	NN
cord-278081-tk7vn1v1	32	57	(	(	-LRB-
cord-278081-tk7vn1v1	32	58	5	5	CD
cord-278081-tk7vn1v1	32	59	)	)	-RRB-
cord-278081-tk7vn1v1	32	60	.	.	.
cord-278081-tk7vn1v1	33	1	Add	add	VB
cord-278081-tk7vn1v1	33	2	to	to	IN
cord-278081-tk7vn1v1	33	3	this	this	DT
cord-278081-tk7vn1v1	33	4	the	the	DT
cord-278081-tk7vn1v1	33	5	fact	fact	NN
cord-278081-tk7vn1v1	33	6	that	that	IN
cord-278081-tk7vn1v1	33	7	in	in	IN
cord-278081-tk7vn1v1	33	8	the	the	DT
cord-278081-tk7vn1v1	33	9	interim	interim	JJ
cord-278081-tk7vn1v1	33	10	the	the	DT
cord-278081-tk7vn1v1	33	11	individual	individual	NN
cord-278081-tk7vn1v1	33	12	has	have	VBZ
cord-278081-tk7vn1v1	33	13	had	have	VBN
cord-278081-tk7vn1v1	33	14	other	other	JJ
cord-278081-tk7vn1v1	33	15	infections	infection	NNS
cord-278081-tk7vn1v1	33	16	caused	cause	VBN
cord-278081-tk7vn1v1	33	17	by	by	IN
cord-278081-tk7vn1v1	33	18	other	other	JJ
cord-278081-tk7vn1v1	33	19	pathogens	pathogen	NNS
cord-278081-tk7vn1v1	33	20	that	that	WDT
cord-278081-tk7vn1v1	33	21	complicate	complicate	VBP
cord-278081-tk7vn1v1	33	22	the	the	DT
cord-278081-tk7vn1v1	33	23	situation	situation	NN
cord-278081-tk7vn1v1	33	24	,	,	,
cord-278081-tk7vn1v1	33	25	potentially	potentially	RB
cord-278081-tk7vn1v1	33	26	triggering	trigger	VBG
cord-278081-tk7vn1v1	33	27	the	the	DT
cord-278081-tk7vn1v1	33	28	actual	actual	JJ
cord-278081-tk7vn1v1	33	29	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	33	30	disease	disease	NN
cord-278081-tk7vn1v1	33	31	for	for	IN
cord-278081-tk7vn1v1	33	32	which	which	WDT
cord-278081-tk7vn1v1	33	33	an	an	DT
cord-278081-tk7vn1v1	33	34	initial	initial	JJ
cord-278081-tk7vn1v1	33	35	EBV	EBV	NNP
cord-278081-tk7vn1v1	33	36	infection	infection	NN
cord-278081-tk7vn1v1	33	37	set	set	VBD
cord-278081-tk7vn1v1	33	38	the	the	DT
cord-278081-tk7vn1v1	33	39	stage	stage	NN
cord-278081-tk7vn1v1	33	40	.	.	.
cord-278081-tk7vn1v1	34	1	A	a	DT
cord-278081-tk7vn1v1	34	2	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	34	3	infection	infection	NN
cord-278081-tk7vn1v1	34	4	with	with	IN
cord-278081-tk7vn1v1	34	5	another	another	DT
cord-278081-tk7vn1v1	34	6	virus	virus	NN
cord-278081-tk7vn1v1	34	7	could	could	MD
cord-278081-tk7vn1v1	34	8	allow	allow	VB
cord-278081-tk7vn1v1	34	9	activation	activation	NN
cord-278081-tk7vn1v1	34	10	of	of	IN
cord-278081-tk7vn1v1	34	11	latent	latent	JJ
cord-278081-tk7vn1v1	34	12	viruses	virus	NNS
cord-278081-tk7vn1v1	34	13	giving	give	VBG
cord-278081-tk7vn1v1	34	14	a	a	DT
cord-278081-tk7vn1v1	34	15	combined	combine	VBN
cord-278081-tk7vn1v1	34	16	stressful	stressful	JJ
cord-278081-tk7vn1v1	34	17	impact	impact	NN
cord-278081-tk7vn1v1	34	18	on	on	IN
cord-278081-tk7vn1v1	34	19	the	the	DT
cord-278081-tk7vn1v1	34	20	cell	cell	NN
cord-278081-tk7vn1v1	34	21	.	.	.
cord-278081-tk7vn1v1	35	1	For	for	IN
cord-278081-tk7vn1v1	35	2	example	example	NN
cord-278081-tk7vn1v1	35	3	,	,	,
cord-278081-tk7vn1v1	35	4	a	a	DT
cord-278081-tk7vn1v1	35	5	primary	primary	JJ
cord-278081-tk7vn1v1	35	6	infection	infection	NN
cord-278081-tk7vn1v1	35	7	by	by	IN
cord-278081-tk7vn1v1	35	8	cytomegalovirus	cytomegalovirus	NNP
cord-278081-tk7vn1v1	35	9	can	can	MD
cord-278081-tk7vn1v1	35	10	lead	lead	VB
cord-278081-tk7vn1v1	35	11	to	to	IN
cord-278081-tk7vn1v1	35	12	reactivation	reactivation	NN
cord-278081-tk7vn1v1	35	13	of	of	IN
cord-278081-tk7vn1v1	35	14	latent	latent	JJ
cord-278081-tk7vn1v1	35	15	EBV	EBV	NNP
cord-278081-tk7vn1v1	35	16	which	which	WDT
cord-278081-tk7vn1v1	35	17	provokes	provoke	VBZ
cord-278081-tk7vn1v1	35	18	an	an	DT
cord-278081-tk7vn1v1	35	19	immune	immune	JJ
cord-278081-tk7vn1v1	35	20	response	response	NN
cord-278081-tk7vn1v1	35	21	(	(	-LRB-
cord-278081-tk7vn1v1	35	22	6	6	CD
cord-278081-tk7vn1v1	35	23	)	)	-RRB-
cord-278081-tk7vn1v1	35	24	.	.	.
cord-278081-tk7vn1v1	36	1	The	the	DT
cord-278081-tk7vn1v1	36	2	induction	induction	NN
cord-278081-tk7vn1v1	36	3	of	of	IN
cord-278081-tk7vn1v1	36	4	one	one	CD
cord-278081-tk7vn1v1	36	5	latent	latent	JJ
cord-278081-tk7vn1v1	36	6	virus	virus	NN
cord-278081-tk7vn1v1	36	7	by	by	IN
cord-278081-tk7vn1v1	36	8	another	another	DT
cord-278081-tk7vn1v1	36	9	virus	virus	NN
cord-278081-tk7vn1v1	36	10	shows	show	VBZ
cord-278081-tk7vn1v1	36	11	the	the	DT
cord-278081-tk7vn1v1	36	12	potential	potential	JJ
cord-278081-tk7vn1v1	36	13	complexity	complexity	NN
cord-278081-tk7vn1v1	36	14	underlying	underlie	VBG
cord-278081-tk7vn1v1	36	15	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	36	16	diseases	disease	NNS
cord-278081-tk7vn1v1	36	17	.	.	.
cord-278081-tk7vn1v1	37	1	The	the	DT
cord-278081-tk7vn1v1	37	2	general	general	JJ
cord-278081-tk7vn1v1	37	3	population	population	NN
cord-278081-tk7vn1v1	37	4	has	have	VBZ
cord-278081-tk7vn1v1	37	5	had	have	VBN
cord-278081-tk7vn1v1	37	6	exposure	exposure	NN
cord-278081-tk7vn1v1	37	7	to	to	IN
cord-278081-tk7vn1v1	37	8	many	many	JJ
cord-278081-tk7vn1v1	37	9	of	of	IN
cord-278081-tk7vn1v1	37	10	the	the	DT
cord-278081-tk7vn1v1	37	11	viruses	virus	NNS
cord-278081-tk7vn1v1	37	12	associated	associate	VBN
cord-278081-tk7vn1v1	37	13	with	with	IN
cord-278081-tk7vn1v1	37	14	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	37	15	diseases	disease	NNS
cord-278081-tk7vn1v1	37	16	but	but	CC
cord-278081-tk7vn1v1	37	17	for	for	IN
cord-278081-tk7vn1v1	37	18	most	most	JJS
cord-278081-tk7vn1v1	37	19	individuals	individual	NNS
cord-278081-tk7vn1v1	37	20	there	there	EX
cord-278081-tk7vn1v1	37	21	is	be	VBZ
cord-278081-tk7vn1v1	37	22	no	no	DT
cord-278081-tk7vn1v1	37	23	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	37	24	disease	disease	NN
cord-278081-tk7vn1v1	37	25	development	development	NN
cord-278081-tk7vn1v1	37	26	,	,	,
cord-278081-tk7vn1v1	37	27	suggesting	suggest	VBG
cord-278081-tk7vn1v1	37	28	that	that	IN
cord-278081-tk7vn1v1	37	29	genetic	genetic	JJ
cord-278081-tk7vn1v1	37	30	susceptibility	susceptibility	NN
cord-278081-tk7vn1v1	37	31	is	be	VBZ
cord-278081-tk7vn1v1	37	32	also	also	RB
cord-278081-tk7vn1v1	37	33	important	important	JJ
cord-278081-tk7vn1v1	37	34	as	as	RB
cord-278081-tk7vn1v1	37	35	well	well	RB
cord-278081-tk7vn1v1	37	36	as	as	IN
cord-278081-tk7vn1v1	37	37	possible	possible	JJ
cord-278081-tk7vn1v1	37	38	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	37	39	and	and	CC
cord-278081-tk7vn1v1	37	40	environmental	environmental	JJ
cord-278081-tk7vn1v1	37	41	factors	factor	NNS
cord-278081-tk7vn1v1	37	42	.	.	.
cord-278081-tk7vn1v1	38	1	As	as	IN
cord-278081-tk7vn1v1	38	2	an	an	DT
cord-278081-tk7vn1v1	38	3	example	example	NN
cord-278081-tk7vn1v1	38	4	,	,	,
cord-278081-tk7vn1v1	38	5	most	most	JJS
cord-278081-tk7vn1v1	38	6	adults	adult	NNS
cord-278081-tk7vn1v1	38	7	have	have	VBP
cord-278081-tk7vn1v1	38	8	had	have	VBN
cord-278081-tk7vn1v1	38	9	exposure	exposure	NN
cord-278081-tk7vn1v1	38	10	to	to	IN
cord-278081-tk7vn1v1	38	11	EBV	EBV	NNP
cord-278081-tk7vn1v1	38	12	but	but	CC
cord-278081-tk7vn1v1	38	13	few	few	JJ
cord-278081-tk7vn1v1	38	14	develop	develop	VBP
cord-278081-tk7vn1v1	38	15	an	an	DT
cord-278081-tk7vn1v1	38	16	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	38	17	disease	disease	NN
cord-278081-tk7vn1v1	38	18	,	,	,
cord-278081-tk7vn1v1	38	19	suggesting	suggest	VBG
cord-278081-tk7vn1v1	38	20	other	other	JJ
cord-278081-tk7vn1v1	38	21	factors	factor	NNS
cord-278081-tk7vn1v1	38	22	are	be	VBP
cord-278081-tk7vn1v1	38	23	involved	involve	VBN
cord-278081-tk7vn1v1	38	24	rather	rather	RB
cord-278081-tk7vn1v1	38	25	than	than	IN
cord-278081-tk7vn1v1	38	26	just	just	RB
cord-278081-tk7vn1v1	38	27	EBV	EBV	NNP
cord-278081-tk7vn1v1	38	28	.	.	.
cord-278081-tk7vn1v1	39	1	A	a	DT
cord-278081-tk7vn1v1	39	2	genetic	genetic	JJ
cord-278081-tk7vn1v1	39	3	possibility	possibility	NN
cord-278081-tk7vn1v1	39	4	for	for	IN
cord-278081-tk7vn1v1	39	5	these	these	DT
cord-278081-tk7vn1v1	39	6	differing	differ	VBG
cord-278081-tk7vn1v1	39	7	responses	response	NNS
cord-278081-tk7vn1v1	39	8	may	may	MD
cord-278081-tk7vn1v1	39	9	be	be	VB
cord-278081-tk7vn1v1	39	10	based	base	VBN
cord-278081-tk7vn1v1	39	11	on	on	IN
cord-278081-tk7vn1v1	39	12	different	different	JJ
cord-278081-tk7vn1v1	39	13	HLA	HLA	NNP
cord-278081-tk7vn1v1	39	14	types	type	NNS
cord-278081-tk7vn1v1	39	15	,	,	,
cord-278081-tk7vn1v1	39	16	for	for	IN
cord-278081-tk7vn1v1	39	17	example	example	NN
cord-278081-tk7vn1v1	39	18	,	,	,
cord-278081-tk7vn1v1	39	19	entry	entry	NN
cord-278081-tk7vn1v1	39	20	of	of	IN
cord-278081-tk7vn1v1	39	21	EBV	EBV	NNP
cord-278081-tk7vn1v1	39	22	into	into	IN
cord-278081-tk7vn1v1	39	23	a	a	DT
cord-278081-tk7vn1v1	39	24	host	host	NN
cord-278081-tk7vn1v1	39	25	cell	cell	NN
cord-278081-tk7vn1v1	39	26	via	via	IN
cord-278081-tk7vn1v1	39	27	binding	binding	NN
cord-278081-tk7vn1v1	39	28	of	of	IN
cord-278081-tk7vn1v1	39	29	the	the	DT
cord-278081-tk7vn1v1	39	30	EBV	EBV	NNP
cord-278081-tk7vn1v1	39	31	's	's	POS
cord-278081-tk7vn1v1	39	32	gp42	gp42	NNS
cord-278081-tk7vn1v1	39	33	glycoprotein	glycoprotein	JJ
cord-278081-tk7vn1v1	39	34	to	to	IN
cord-278081-tk7vn1v1	39	35	human	human	JJ
cord-278081-tk7vn1v1	39	36	CD21	CD21	NNP
cord-278081-tk7vn1v1	39	37	and	and	CC
cord-278081-tk7vn1v1	39	38	lymphocytic	lymphocytic	JJ
cord-278081-tk7vn1v1	39	39	antigen	antigen	NN
cord-278081-tk7vn1v1	39	40	type	type	NN
cord-278081-tk7vn1v1	39	41	HLA	HLA	NNP
cord-278081-tk7vn1v1	39	42	-	-	HYPH
cord-278081-tk7vn1v1	39	43	DR	DR	NNP
cord-278081-tk7vn1v1	39	44	.	.	.
cord-278081-tk7vn1v1	40	1	Other	other	JJ
cord-278081-tk7vn1v1	40	2	HLA	HLA	NNP
cord-278081-tk7vn1v1	40	3	sub	sub	NN
cord-278081-tk7vn1v1	40	4	-	-	NNS
cord-278081-tk7vn1v1	40	5	types	type	NNS
cord-278081-tk7vn1v1	40	6	may	may	MD
cord-278081-tk7vn1v1	40	7	have	have	VB
cord-278081-tk7vn1v1	40	8	different	different	JJ
cord-278081-tk7vn1v1	40	9	expression	expression	NN
cord-278081-tk7vn1v1	40	10	levels	level	NNS
cord-278081-tk7vn1v1	40	11	or	or	CC
cord-278081-tk7vn1v1	40	12	have	have	VBP
cord-278081-tk7vn1v1	40	13	different	different	JJ
cord-278081-tk7vn1v1	40	14	affinity	affinity	NN
cord-278081-tk7vn1v1	40	15	for	for	IN
cord-278081-tk7vn1v1	40	16	the	the	DT
cord-278081-tk7vn1v1	40	17	gp42	gp42	NNS
cord-278081-tk7vn1v1	40	18	and	and	CC
cord-278081-tk7vn1v1	40	19	not	not	RB
cord-278081-tk7vn1v1	40	20	be	be	VB
cord-278081-tk7vn1v1	40	21	as	as	RB
cord-278081-tk7vn1v1	40	22	compliant	compliant	JJ
cord-278081-tk7vn1v1	40	23	for	for	IN
cord-278081-tk7vn1v1	40	24	EBV	EBV	NNP
cord-278081-tk7vn1v1	40	25	entry	entry	NN
cord-278081-tk7vn1v1	40	26	.	.	.
cord-278081-tk7vn1v1	41	1	In	in	IN
cord-278081-tk7vn1v1	41	2	addition	addition	NN
cord-278081-tk7vn1v1	41	3	,	,	,
cord-278081-tk7vn1v1	41	4	the	the	DT
cord-278081-tk7vn1v1	41	5	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	41	6	portion	portion	NN
cord-278081-tk7vn1v1	41	7	of	of	IN
cord-278081-tk7vn1v1	41	8	the	the	DT
cord-278081-tk7vn1v1	41	9	EBV	EBV	NNP
cord-278081-tk7vn1v1	41	10	BZLF2	BZLF2	NNP
cord-278081-tk7vn1v1	41	11	protein	protein	NN
cord-278081-tk7vn1v1	41	12	can	can	MD
cord-278081-tk7vn1v1	41	13	suppress	suppress	VB
cord-278081-tk7vn1v1	41	14	antigen	antigen	NN
cord-278081-tk7vn1v1	41	15	presentation	presentation	NN
cord-278081-tk7vn1v1	41	16	by	by	IN
cord-278081-tk7vn1v1	41	17	binding	bind	VBG
cord-278081-tk7vn1v1	41	18	HLA	HLA	NNP
cord-278081-tk7vn1v1	41	19	-	-	HYPH
cord-278081-tk7vn1v1	41	20	DR	DR	NNP
cord-278081-tk7vn1v1	41	21	delaying	delay	VBG
cord-278081-tk7vn1v1	41	22	detection	detection	NN
cord-278081-tk7vn1v1	41	23	of	of	IN
cord-278081-tk7vn1v1	41	24	the	the	DT
cord-278081-tk7vn1v1	41	25	EBV	EBV	NNP
cord-278081-tk7vn1v1	41	26	(	(	-LRB-
cord-278081-tk7vn1v1	41	27	7	7	CD
cord-278081-tk7vn1v1	41	28	)	)	-RRB-
cord-278081-tk7vn1v1	41	29	.	.	.
cord-278081-tk7vn1v1	42	1	Table	table	NN
cord-278081-tk7vn1v1	42	2	1	1	CD
cord-278081-tk7vn1v1	42	3	lists	list	VBZ
cord-278081-tk7vn1v1	42	4	many	many	JJ
cord-278081-tk7vn1v1	42	5	of	of	IN
cord-278081-tk7vn1v1	42	6	the	the	DT
cord-278081-tk7vn1v1	42	7	viruses	virus	NNS
cord-278081-tk7vn1v1	42	8	that	that	WDT
cord-278081-tk7vn1v1	42	9	have	have	VBP
cord-278081-tk7vn1v1	42	10	shown	show	VBN
cord-278081-tk7vn1v1	42	11	associations	association	NNS
cord-278081-tk7vn1v1	42	12	with	with	IN
cord-278081-tk7vn1v1	42	13	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	42	14	diseases	disease	NNS
cord-278081-tk7vn1v1	42	15	.	.	.
cord-278081-tk7vn1v1	43	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	43	2	should	should	MD
cord-278081-tk7vn1v1	43	3	note	note	VB
cord-278081-tk7vn1v1	43	4	that	that	IN
cord-278081-tk7vn1v1	43	5	there	there	EX
cord-278081-tk7vn1v1	43	6	is	be	VBZ
cord-278081-tk7vn1v1	43	7	variety	variety	NN
cord-278081-tk7vn1v1	43	8	in	in	IN
cord-278081-tk7vn1v1	43	9	the	the	DT
cord-278081-tk7vn1v1	43	10	route	route	NN
cord-278081-tk7vn1v1	43	11	of	of	IN
cord-278081-tk7vn1v1	43	12	transmission	transmission	NN
cord-278081-tk7vn1v1	43	13	and	and	CC
cord-278081-tk7vn1v1	43	14	entry	entry	NN
cord-278081-tk7vn1v1	43	15	among	among	IN
cord-278081-tk7vn1v1	43	16	these	these	DT
cord-278081-tk7vn1v1	43	17	viruses	virus	NNS
cord-278081-tk7vn1v1	43	18	:	:	:
cord-278081-tk7vn1v1	43	19	(	(	-LRB-
cord-278081-tk7vn1v1	43	20	1	1	LS
cord-278081-tk7vn1v1	43	21	)	)	-RRB-
cord-278081-tk7vn1v1	43	22	respiratory	respiratory	JJ
cord-278081-tk7vn1v1	43	23	and	and	CC
cord-278081-tk7vn1v1	43	24	oral	oral	JJ
cord-278081-tk7vn1v1	43	25	secretions	secretion	NNS
cord-278081-tk7vn1v1	43	26	(	(	-LRB-
cord-278081-tk7vn1v1	43	27	saliva	saliva	NN
cord-278081-tk7vn1v1	43	28	,	,	,
cord-278081-tk7vn1v1	43	29	sputum	sputum	NN
cord-278081-tk7vn1v1	43	30	,	,	,
cord-278081-tk7vn1v1	43	31	nasal	nasal	JJ
cord-278081-tk7vn1v1	43	32	mucus	mucus	NN
cord-278081-tk7vn1v1	43	33	)	)	-RRB-
cord-278081-tk7vn1v1	43	34	(	(	-LRB-
cord-278081-tk7vn1v1	43	35	e.g.	e.g.	RB
cord-278081-tk7vn1v1	43	36	,	,	,
cord-278081-tk7vn1v1	43	37	EBV	EBV	NNP
cord-278081-tk7vn1v1	43	38	,	,	,
cord-278081-tk7vn1v1	43	39	parvovirus	parvovirus	NN
cord-278081-tk7vn1v1	43	40	)	)	-RRB-
cord-278081-tk7vn1v1	43	41	;	;	:
cord-278081-tk7vn1v1	43	42	(	(	-LRB-
cord-278081-tk7vn1v1	43	43	2	2	LS
cord-278081-tk7vn1v1	43	44	)	)	-RRB-
cord-278081-tk7vn1v1	43	45	gut	gut	NN
cord-278081-tk7vn1v1	43	46	(	(	-LRB-
cord-278081-tk7vn1v1	43	47	e.g.	e.g.	RB
cord-278081-tk7vn1v1	43	48	,	,	,
cord-278081-tk7vn1v1	43	49	enteroviruses	enteroviruses	NNP
cord-278081-tk7vn1v1	43	50	)	)	-RRB-
cord-278081-tk7vn1v1	43	51	;	;	:
cord-278081-tk7vn1v1	43	52	(	(	-LRB-
cord-278081-tk7vn1v1	43	53	3	3	LS
cord-278081-tk7vn1v1	43	54	)	)	-RRB-
cord-278081-tk7vn1v1	43	55	insect	insect	NN
cord-278081-tk7vn1v1	43	56	vector	vector	NN
cord-278081-tk7vn1v1	43	57	transmission	transmission	NN
cord-278081-tk7vn1v1	43	58	(	(	-LRB-
cord-278081-tk7vn1v1	43	59	e.g.	e.g.	RB
cord-278081-tk7vn1v1	43	60	,	,	,
cord-278081-tk7vn1v1	43	61	mosquitos	mosquitos	NN
cord-278081-tk7vn1v1	43	62	for	for	IN
cord-278081-tk7vn1v1	43	63	Zika	Zika	NNP
cord-278081-tk7vn1v1	43	64	,	,	,
cord-278081-tk7vn1v1	43	65	West	West	NNP
cord-278081-tk7vn1v1	43	66	Nile	Nile	NNP
cord-278081-tk7vn1v1	43	67	)	)	-RRB-
cord-278081-tk7vn1v1	43	68	;	;	:
cord-278081-tk7vn1v1	43	69	(	(	-LRB-
cord-278081-tk7vn1v1	43	70	4	4	LS
cord-278081-tk7vn1v1	43	71	)	)	-RRB-
cord-278081-tk7vn1v1	43	72	sexual	sexual	JJ
cord-278081-tk7vn1v1	43	73	interactions	interaction	NNS
cord-278081-tk7vn1v1	43	74	(	(	-LRB-
cord-278081-tk7vn1v1	43	75	e.g.	e.g.	RB
cord-278081-tk7vn1v1	43	76	,	,	,
cord-278081-tk7vn1v1	43	77	HPV	HPV	NNP
cord-278081-tk7vn1v1	43	78	,	,	,
cord-278081-tk7vn1v1	43	79	HIV	HIV	NNP
cord-278081-tk7vn1v1	43	80	)	)	-RRB-
cord-278081-tk7vn1v1	43	81	;	;	:
cord-278081-tk7vn1v1	43	82	and	and	CC
cord-278081-tk7vn1v1	43	83	(	(	-LRB-
cord-278081-tk7vn1v1	43	84	5	5	LS
cord-278081-tk7vn1v1	43	85	)	)	-RRB-
cord-278081-tk7vn1v1	43	86	transfusions	transfusion	NNS
cord-278081-tk7vn1v1	43	87	(	(	-LRB-
cord-278081-tk7vn1v1	43	88	e.g.	e.g.	RB
cord-278081-tk7vn1v1	43	89	,	,	,
cord-278081-tk7vn1v1	43	90	HIV	HIV	NNP
cord-278081-tk7vn1v1	43	91	)	)	-RRB-
cord-278081-tk7vn1v1	43	92	.	.	.
cord-278081-tk7vn1v1	44	1	The	the	DT
cord-278081-tk7vn1v1	44	2	tissue	tissue	NN
cord-278081-tk7vn1v1	44	3	types	type	NNS
cord-278081-tk7vn1v1	44	4	in	in	IN
cord-278081-tk7vn1v1	44	5	which	which	WDT
cord-278081-tk7vn1v1	44	6	viral	viral	JJ
cord-278081-tk7vn1v1	44	7	sequestration	sequestration	NN
cord-278081-tk7vn1v1	44	8	occurs	occur	VBZ
cord-278081-tk7vn1v1	44	9	may	may	MD
cord-278081-tk7vn1v1	44	10	vary	vary	VB
cord-278081-tk7vn1v1	44	11	,	,	,
cord-278081-tk7vn1v1	44	12	such	such	JJ
cord-278081-tk7vn1v1	44	13	as	as	IN
cord-278081-tk7vn1v1	44	14	EBV	EBV	NNP
cord-278081-tk7vn1v1	44	15	behind	behind	IN
cord-278081-tk7vn1v1	44	16	the	the	DT
cord-278081-tk7vn1v1	44	17	blood	blood	NN
cord-278081-tk7vn1v1	44	18	-	-	HYPH
cord-278081-tk7vn1v1	44	19	brain	brain	NN
cord-278081-tk7vn1v1	44	20	barrier	barrier	NN
cord-278081-tk7vn1v1	44	21	associated	associate	VBN
cord-278081-tk7vn1v1	44	22	with	with	IN
cord-278081-tk7vn1v1	44	23	MS	MS	NNP
cord-278081-tk7vn1v1	44	24	or	or	CC
cord-278081-tk7vn1v1	44	25	possible	possible	JJ
cord-278081-tk7vn1v1	44	26	EBV	EBV	NNP
cord-278081-tk7vn1v1	44	27	in	in	IN
cord-278081-tk7vn1v1	44	28	the	the	DT
cord-278081-tk7vn1v1	44	29	synovium	synovium	NN
cord-278081-tk7vn1v1	44	30	associated	associate	VBN
cord-278081-tk7vn1v1	44	31	with	with	IN
cord-278081-tk7vn1v1	44	32	RA	RA	NNP
cord-278081-tk7vn1v1	44	33	.	.	.
cord-278081-tk7vn1v1	45	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	45	2	should	should	MD
cord-278081-tk7vn1v1	45	3	also	also	RB
cord-278081-tk7vn1v1	45	4	note	note	VB
cord-278081-tk7vn1v1	45	5	that	that	IN
cord-278081-tk7vn1v1	45	6	there	there	EX
cord-278081-tk7vn1v1	45	7	are	be	VBP
cord-278081-tk7vn1v1	45	8	both	both	DT
cord-278081-tk7vn1v1	45	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	45	10	and	and	CC
cord-278081-tk7vn1v1	45	11	DNA	dna	NN
cord-278081-tk7vn1v1	45	12	viruses	virus	NNS
cord-278081-tk7vn1v1	45	13	listed	list	VBN
cord-278081-tk7vn1v1	45	14	in	in	IN
cord-278081-tk7vn1v1	45	15	Table	Table	NNP
cord-278081-tk7vn1v1	45	16	1	1	CD
cord-278081-tk7vn1v1	45	17	and	and	CC
cord-278081-tk7vn1v1	45	18	most	most	JJS
cord-278081-tk7vn1v1	45	19	of	of	IN
cord-278081-tk7vn1v1	45	20	these	these	DT
cord-278081-tk7vn1v1	45	21	viruses	virus	NNS
cord-278081-tk7vn1v1	45	22	can	can	MD
cord-278081-tk7vn1v1	45	23	persist	persist	VB
cord-278081-tk7vn1v1	45	24	in	in	IN
cord-278081-tk7vn1v1	45	25	a	a	DT
cord-278081-tk7vn1v1	45	26	latent	latent	JJ
cord-278081-tk7vn1v1	45	27	state	state	NN
cord-278081-tk7vn1v1	45	28	in	in	IN
cord-278081-tk7vn1v1	45	29	the	the	DT
cord-278081-tk7vn1v1	45	30	host	host	NN
cord-278081-tk7vn1v1	45	31	.	.	.
cord-278081-tk7vn1v1	46	1	Appearance	appearance	NN
cord-278081-tk7vn1v1	46	2	of	of	IN
cord-278081-tk7vn1v1	46	3	viral	viral	JJ
cord-278081-tk7vn1v1	46	4	antigens	antigen	NNS
cord-278081-tk7vn1v1	46	5	does	do	VBZ
cord-278081-tk7vn1v1	46	6	not	not	RB
cord-278081-tk7vn1v1	46	7	necessarily	necessarily	RB
cord-278081-tk7vn1v1	46	8	mean	mean	VB
cord-278081-tk7vn1v1	46	9	that	that	IN
cord-278081-tk7vn1v1	46	10	the	the	DT
cord-278081-tk7vn1v1	46	11	virus	virus	NN
cord-278081-tk7vn1v1	46	12	is	be	VBZ
cord-278081-tk7vn1v1	46	13	the	the	DT
cord-278081-tk7vn1v1	46	14	cause	cause	NN
cord-278081-tk7vn1v1	46	15	of	of	IN
cord-278081-tk7vn1v1	46	16	the	the	DT
cord-278081-tk7vn1v1	46	17	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	46	18	disease	disease	NN
cord-278081-tk7vn1v1	46	19	episode	episode	NN
cord-278081-tk7vn1v1	46	20	since	since	IN
cord-278081-tk7vn1v1	46	21	it	-PRON-	PRP
cord-278081-tk7vn1v1	46	22	may	may	MD
cord-278081-tk7vn1v1	46	23	only	only	RB
cord-278081-tk7vn1v1	46	24	be	be	VB
cord-278081-tk7vn1v1	46	25	the	the	DT
cord-278081-tk7vn1v1	46	26	result	result	NN
cord-278081-tk7vn1v1	46	27	of	of	IN
cord-278081-tk7vn1v1	46	28	stress	stress	NN
cord-278081-tk7vn1v1	46	29	from	from	IN
cord-278081-tk7vn1v1	46	30	an	an	DT
cord-278081-tk7vn1v1	46	31	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	46	32	disease	disease	NN
cord-278081-tk7vn1v1	46	33	episode	episode	NN
cord-278081-tk7vn1v1	46	34	that	that	WDT
cord-278081-tk7vn1v1	46	35	leads	lead	VBZ
cord-278081-tk7vn1v1	46	36	to	to	IN
cord-278081-tk7vn1v1	46	37	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	46	38	activation	activation	NN
cord-278081-tk7vn1v1	46	39	of	of	IN
cord-278081-tk7vn1v1	46	40	a	a	DT
cord-278081-tk7vn1v1	46	41	hidden	hidden	JJ
cord-278081-tk7vn1v1	46	42	virus	virus	NN
cord-278081-tk7vn1v1	46	43	.	.	.
cord-278081-tk7vn1v1	47	1	For	for	IN
cord-278081-tk7vn1v1	47	2	most	most	JJS
cord-278081-tk7vn1v1	47	3	of	of	IN
cord-278081-tk7vn1v1	47	4	these	these	DT
cord-278081-tk7vn1v1	47	5	associations	association	NNS
cord-278081-tk7vn1v1	47	6	(	(	-LRB-
cord-278081-tk7vn1v1	47	7	Table	table	NN
cord-278081-tk7vn1v1	47	8	1	1	CD
cord-278081-tk7vn1v1	47	9	)	)	-RRB-
cord-278081-tk7vn1v1	47	10	,	,	,
cord-278081-tk7vn1v1	47	11	it	-PRON-	PRP
cord-278081-tk7vn1v1	47	12	remains	remain	VBZ
cord-278081-tk7vn1v1	47	13	to	to	TO
cord-278081-tk7vn1v1	47	14	be	be	VB
cord-278081-tk7vn1v1	47	15	determined	determine	VBN
cord-278081-tk7vn1v1	47	16	if	if	IN
cord-278081-tk7vn1v1	47	17	the	the	DT
cord-278081-tk7vn1v1	47	18	virus	virus	NN
cord-278081-tk7vn1v1	47	19	is	be	VBZ
cord-278081-tk7vn1v1	47	20	the	the	DT
cord-278081-tk7vn1v1	47	21	causative	causative	JJ
cord-278081-tk7vn1v1	47	22	agent	agent	NN
cord-278081-tk7vn1v1	47	23	,	,	,
cord-278081-tk7vn1v1	47	24	one	one	CD
cord-278081-tk7vn1v1	47	25	of	of	IN
cord-278081-tk7vn1v1	47	26	several	several	JJ
cord-278081-tk7vn1v1	47	27	combined	combine	VBN
cord-278081-tk7vn1v1	47	28	contributing	contribute	VBG
cord-278081-tk7vn1v1	47	29	agents	agent	NNS
cord-278081-tk7vn1v1	47	30	,	,	,
cord-278081-tk7vn1v1	47	31	or	or	CC
cord-278081-tk7vn1v1	47	32	simply	simply	RB
cord-278081-tk7vn1v1	47	33	appearing	appear	VBG
cord-278081-tk7vn1v1	47	34	as	as	IN
cord-278081-tk7vn1v1	47	35	a	a	DT
cord-278081-tk7vn1v1	47	36	result	result	NN
cord-278081-tk7vn1v1	47	37	of	of	IN
cord-278081-tk7vn1v1	47	38	impaired	impaired	JJ
cord-278081-tk7vn1v1	47	39	host	host	NN
cord-278081-tk7vn1v1	47	40	cell	cell	NN
cord-278081-tk7vn1v1	47	41	suppression	suppression	NN
cord-278081-tk7vn1v1	47	42	of	of	IN
cord-278081-tk7vn1v1	47	43	the	the	DT
cord-278081-tk7vn1v1	47	44	virus	virus	NN
cord-278081-tk7vn1v1	47	45	.	.	.
cord-278081-tk7vn1v1	48	1	For	for	IN
cord-278081-tk7vn1v1	48	2	example	example	NN
cord-278081-tk7vn1v1	48	3	,	,	,
cord-278081-tk7vn1v1	48	4	the	the	DT
cord-278081-tk7vn1v1	48	5	measles	measle	NNS
cord-278081-tk7vn1v1	48	6	virus	virus	NN
cord-278081-tk7vn1v1	48	7	is	be	VBZ
cord-278081-tk7vn1v1	48	8	suspected	suspect	VBN
cord-278081-tk7vn1v1	48	9	of	of	IN
cord-278081-tk7vn1v1	48	10	involvement	involvement	NN
cord-278081-tk7vn1v1	48	11	in	in	IN
cord-278081-tk7vn1v1	48	12	MS	MS	NNP
cord-278081-tk7vn1v1	48	13	due	due	IN
cord-278081-tk7vn1v1	48	14	to	to	IN
cord-278081-tk7vn1v1	48	15	the	the	DT
cord-278081-tk7vn1v1	48	16	appearance	appearance	NN
cord-278081-tk7vn1v1	48	17	of	of	IN
cord-278081-tk7vn1v1	48	18	antibodies	antibody	NNS
cord-278081-tk7vn1v1	48	19	to	to	IN
cord-278081-tk7vn1v1	48	20	measles	measle	NNS
cord-278081-tk7vn1v1	48	21	virus	virus	NN
cord-278081-tk7vn1v1	48	22	antigens	antigen	NNS
cord-278081-tk7vn1v1	48	23	in	in	IN
cord-278081-tk7vn1v1	48	24	cerebrospinal	cerebrospinal	JJ
cord-278081-tk7vn1v1	48	25	fluid	fluid	NN
cord-278081-tk7vn1v1	48	26	of	of	IN
cord-278081-tk7vn1v1	48	27	MS	MS	NNP
cord-278081-tk7vn1v1	48	28	patients	patient	NNS
cord-278081-tk7vn1v1	48	29	(	(	-LRB-
cord-278081-tk7vn1v1	48	30	36	36	CD
cord-278081-tk7vn1v1	48	31	)	)	-RRB-
cord-278081-tk7vn1v1	48	32	.	.	.
cord-278081-tk7vn1v1	49	1	Whether	whether	IN
cord-278081-tk7vn1v1	49	2	the	the	DT
cord-278081-tk7vn1v1	49	3	MS	MS	NNP
cord-278081-tk7vn1v1	49	4	is	be	VBZ
cord-278081-tk7vn1v1	49	5	a	a	DT
cord-278081-tk7vn1v1	49	6	direct	direct	JJ
cord-278081-tk7vn1v1	49	7	result	result	NN
cord-278081-tk7vn1v1	49	8	of	of	IN
cord-278081-tk7vn1v1	49	9	the	the	DT
cord-278081-tk7vn1v1	49	10	measles	measle	NNS
cord-278081-tk7vn1v1	49	11	virus	virus	NN
cord-278081-tk7vn1v1	49	12	or	or	CC
cord-278081-tk7vn1v1	49	13	the	the	DT
cord-278081-tk7vn1v1	49	14	appearance	appearance	NN
cord-278081-tk7vn1v1	49	15	of	of	IN
cord-278081-tk7vn1v1	49	16	measles	measles	NN
cord-278081-tk7vn1v1	49	17	antigens	antigen	NNS
cord-278081-tk7vn1v1	49	18	is	be	VBZ
cord-278081-tk7vn1v1	49	19	a	a	DT
cord-278081-tk7vn1v1	49	20	consequence	consequence	NN
cord-278081-tk7vn1v1	49	21	of	of	IN
cord-278081-tk7vn1v1	49	22	the	the	DT
cord-278081-tk7vn1v1	49	23	MS	MS	NNP
cord-278081-tk7vn1v1	49	24	or	or	CC
cord-278081-tk7vn1v1	49	25	is	be	VBZ
cord-278081-tk7vn1v1	49	26	simply	simply	RB
cord-278081-tk7vn1v1	49	27	coincidental	coincidental	JJ
cord-278081-tk7vn1v1	49	28	is	be	VBZ
cord-278081-tk7vn1v1	49	29	not	not	RB
cord-278081-tk7vn1v1	49	30	known	know	VBN
cord-278081-tk7vn1v1	49	31	.	.	.
cord-278081-tk7vn1v1	50	1	There	there	EX
cord-278081-tk7vn1v1	50	2	may	may	MD
cord-278081-tk7vn1v1	50	3	,	,	,
cord-278081-tk7vn1v1	50	4	in	in	IN
cord-278081-tk7vn1v1	50	5	fact	fact	NN
cord-278081-tk7vn1v1	50	6	,	,	,
cord-278081-tk7vn1v1	50	7	be	be	VB
cord-278081-tk7vn1v1	50	8	another	another	DT
cord-278081-tk7vn1v1	50	9	virus	virus	NN
cord-278081-tk7vn1v1	50	10	or	or	CC
cord-278081-tk7vn1v1	50	11	another	another	DT
cord-278081-tk7vn1v1	50	12	environmental	environmental	JJ
cord-278081-tk7vn1v1	50	13	agent	agent	NN
cord-278081-tk7vn1v1	50	14	that	that	WDT
cord-278081-tk7vn1v1	50	15	has	have	VBZ
cord-278081-tk7vn1v1	50	16	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	50	17	the	the	DT
cord-278081-tk7vn1v1	50	18	suppression	suppression	NN
cord-278081-tk7vn1v1	50	19	of	of	IN
cord-278081-tk7vn1v1	50	20	the	the	DT
cord-278081-tk7vn1v1	50	21	latent	latent	JJ
cord-278081-tk7vn1v1	50	22	measles	measle	NNS
cord-278081-tk7vn1v1	50	23	virus	virus	NN
cord-278081-tk7vn1v1	50	24	.	.	.
cord-278081-tk7vn1v1	51	1	As	as	IN
cord-278081-tk7vn1v1	51	2	it	-PRON-	PRP
cord-278081-tk7vn1v1	51	3	is	be	VBZ
cord-278081-tk7vn1v1	51	4	,	,	,
cord-278081-tk7vn1v1	51	5	the	the	DT
cord-278081-tk7vn1v1	51	6	situation	situation	NN
cord-278081-tk7vn1v1	51	7	is	be	VBZ
cord-278081-tk7vn1v1	51	8	even	even	RB
cord-278081-tk7vn1v1	51	9	more	more	RBR
cord-278081-tk7vn1v1	51	10	perplexing	perplexing	JJ
cord-278081-tk7vn1v1	51	11	since	since	IN
cord-278081-tk7vn1v1	51	12	the	the	DT
cord-278081-tk7vn1v1	51	13	introduction	introduction	NN
cord-278081-tk7vn1v1	51	14	of	of	IN
cord-278081-tk7vn1v1	51	15	measles	measles	JJ
cord-278081-tk7vn1v1	51	16	vaccination	vaccination	NN
cord-278081-tk7vn1v1	51	17	for	for	IN
cord-278081-tk7vn1v1	51	18	the	the	DT
cord-278081-tk7vn1v1	51	19	general	general	JJ
cord-278081-tk7vn1v1	51	20	population	population	NN
cord-278081-tk7vn1v1	51	21	has	have	VBZ
cord-278081-tk7vn1v1	51	22	not	not	RB
cord-278081-tk7vn1v1	51	23	caused	cause	VBN
cord-278081-tk7vn1v1	51	24	a	a	DT
cord-278081-tk7vn1v1	51	25	significant	significant	JJ
cord-278081-tk7vn1v1	51	26	change	change	NN
cord-278081-tk7vn1v1	51	27	in	in	IN
cord-278081-tk7vn1v1	51	28	the	the	DT
cord-278081-tk7vn1v1	51	29	occurrence	occurrence	NN
cord-278081-tk7vn1v1	51	30	rate	rate	NN
cord-278081-tk7vn1v1	51	31	of	of	IN
cord-278081-tk7vn1v1	51	32	MS	MS	NNP
cord-278081-tk7vn1v1	51	33	(	(	-LRB-
cord-278081-tk7vn1v1	51	34	37	37	CD
cord-278081-tk7vn1v1	51	35	)	)	-RRB-
cord-278081-tk7vn1v1	51	36	.	.	.
cord-278081-tk7vn1v1	52	1	Other	other	JJ
cord-278081-tk7vn1v1	52	2	viruses	virus	NNS
cord-278081-tk7vn1v1	52	3	with	with	IN
cord-278081-tk7vn1v1	52	4	an	an	DT
cord-278081-tk7vn1v1	52	5	infrequent	infrequent	JJ
cord-278081-tk7vn1v1	52	6	association	association	NN
cord-278081-tk7vn1v1	52	7	with	with	IN
cord-278081-tk7vn1v1	52	8	an	an	DT
cord-278081-tk7vn1v1	52	9	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	52	10	response	response	NN
cord-278081-tk7vn1v1	52	11	can	can	MD
cord-278081-tk7vn1v1	52	12	have	have	VB
cord-278081-tk7vn1v1	52	13	reemergence	reemergence	NN
cord-278081-tk7vn1v1	52	14	in	in	IN
cord-278081-tk7vn1v1	52	15	other	other	JJ
cord-278081-tk7vn1v1	52	16	forms	form	NNS
cord-278081-tk7vn1v1	52	17	,	,	,
cord-278081-tk7vn1v1	52	18	such	such	JJ
cord-278081-tk7vn1v1	52	19	as	as	IN
cord-278081-tk7vn1v1	52	20	the	the	DT
cord-278081-tk7vn1v1	52	21	varicella	varicella	NN
cord-278081-tk7vn1v1	52	22	zoster	zoster	NN
cord-278081-tk7vn1v1	52	23	virus	virus	NN
cord-278081-tk7vn1v1	52	24	which	which	WDT
cord-278081-tk7vn1v1	52	25	causes	cause	VBZ
cord-278081-tk7vn1v1	52	26	chicken	chicken	NN
cord-278081-tk7vn1v1	52	27	pox	pox	NN
cord-278081-tk7vn1v1	52	28	and	and	CC
cord-278081-tk7vn1v1	52	29	which	which	WDT
cord-278081-tk7vn1v1	52	30	can	can	MD
cord-278081-tk7vn1v1	52	31	reemerge	reemerge	VB
cord-278081-tk7vn1v1	52	32	as	as	IN
cord-278081-tk7vn1v1	52	33	shingles	shingle	NNS
cord-278081-tk7vn1v1	52	34	and	and	CC
cord-278081-tk7vn1v1	52	35	is	be	VBZ
cord-278081-tk7vn1v1	52	36	associated	associate	VBN
cord-278081-tk7vn1v1	52	37	with	with	IN
cord-278081-tk7vn1v1	52	38	MS	MS	NNP
cord-278081-tk7vn1v1	52	39	(	(	-LRB-
cord-278081-tk7vn1v1	52	40	38	38	CD
cord-278081-tk7vn1v1	52	41	)	)	-RRB-
cord-278081-tk7vn1v1	52	42	.	.	.
cord-278081-tk7vn1v1	53	1	And	and	CC
cord-278081-tk7vn1v1	53	2	we	-PRON-	PRP
cord-278081-tk7vn1v1	53	3	should	should	MD
cord-278081-tk7vn1v1	53	4	bear	bear	VB
cord-278081-tk7vn1v1	53	5	in	in	IN
cord-278081-tk7vn1v1	53	6	mind	mind	NN
cord-278081-tk7vn1v1	53	7	that	that	IN
cord-278081-tk7vn1v1	53	8	human	human	JJ
cord-278081-tk7vn1v1	53	9	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	53	10	retroviruses	retrovirus	NNS
cord-278081-tk7vn1v1	53	11	are	be	VBP
cord-278081-tk7vn1v1	53	12	suspected	suspect	VBN
cord-278081-tk7vn1v1	53	13	of	of	IN
cord-278081-tk7vn1v1	53	14	involvement	involvement	NN
cord-278081-tk7vn1v1	53	15	in	in	IN
cord-278081-tk7vn1v1	53	16	serious	serious	JJ
cord-278081-tk7vn1v1	53	17	diseases	disease	NNS
cord-278081-tk7vn1v1	53	18	,	,	,
cord-278081-tk7vn1v1	53	19	including	include	VBG
cord-278081-tk7vn1v1	53	20	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	53	21	diseases	disease	NNS
cord-278081-tk7vn1v1	53	22	(	(	-LRB-
cord-278081-tk7vn1v1	53	23	25	25	CD
cord-278081-tk7vn1v1	53	24	,	,	,
cord-278081-tk7vn1v1	53	25	39	39	CD
cord-278081-tk7vn1v1	53	26	)	)	-RRB-
cord-278081-tk7vn1v1	53	27	.	.	.
cord-278081-tk7vn1v1	54	1	Among	among	IN
cord-278081-tk7vn1v1	54	2	the	the	DT
cord-278081-tk7vn1v1	54	3	viruses	virus	NNS
cord-278081-tk7vn1v1	54	4	listed	list	VBN
cord-278081-tk7vn1v1	54	5	in	in	IN
cord-278081-tk7vn1v1	54	6	Table	Table	NNP
cord-278081-tk7vn1v1	54	7	1	1	CD
cord-278081-tk7vn1v1	54	8	,	,	,
cord-278081-tk7vn1v1	54	9	EBV	EBV	NNP
cord-278081-tk7vn1v1	54	10	has	have	VBZ
cord-278081-tk7vn1v1	54	11	received	receive	VBN
cord-278081-tk7vn1v1	54	12	the	the	DT
cord-278081-tk7vn1v1	54	13	most	most	JJS
cord-278081-tk7vn1v1	54	14	attention	attention	NN
cord-278081-tk7vn1v1	54	15	as	as	IN
cord-278081-tk7vn1v1	54	16	a	a	DT
cord-278081-tk7vn1v1	54	17	virus	virus	NN
cord-278081-tk7vn1v1	54	18	with	with	IN
cord-278081-tk7vn1v1	54	19	links	link	NNS
cord-278081-tk7vn1v1	54	20	to	to	IN
cord-278081-tk7vn1v1	54	21	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	54	22	diseases	disease	NNS
cord-278081-tk7vn1v1	54	23	(	(	-LRB-
cord-278081-tk7vn1v1	54	24	15	15	CD
cord-278081-tk7vn1v1	54	25	,	,	,
cord-278081-tk7vn1v1	54	26	40	40	CD
cord-278081-tk7vn1v1	54	27	)	)	-RRB-
cord-278081-tk7vn1v1	54	28	.	.	.
cord-278081-tk7vn1v1	55	1	An	an	DT
cord-278081-tk7vn1v1	55	2	association	association	NN
cord-278081-tk7vn1v1	55	3	with	with	IN
cord-278081-tk7vn1v1	55	4	EBV	EBV	NNP
cord-278081-tk7vn1v1	55	5	infection	infection	NN
cord-278081-tk7vn1v1	55	6	has	have	VBZ
cord-278081-tk7vn1v1	55	7	been	be	VBN
cord-278081-tk7vn1v1	55	8	observed	observe	VBN
cord-278081-tk7vn1v1	55	9	in	in	IN
cord-278081-tk7vn1v1	55	10	SLE	SLE	NNP
cord-278081-tk7vn1v1	55	11	(	(	-LRB-
cord-278081-tk7vn1v1	55	12	41	41	CD
cord-278081-tk7vn1v1	55	13	,	,	,
cord-278081-tk7vn1v1	55	14	42	42	CD
cord-278081-tk7vn1v1	55	15	)	)	-RRB-
cord-278081-tk7vn1v1	55	16	,	,	,
cord-278081-tk7vn1v1	55	17	MS	MS	NNP
cord-278081-tk7vn1v1	55	18	(	(	-LRB-
cord-278081-tk7vn1v1	55	19	43	43	CD
cord-278081-tk7vn1v1	55	20	)	)	-RRB-
cord-278081-tk7vn1v1	55	21	,	,	,
cord-278081-tk7vn1v1	55	22	RA	RA	NNP
cord-278081-tk7vn1v1	55	23	,	,	,
cord-278081-tk7vn1v1	55	24	and	and	CC
cord-278081-tk7vn1v1	55	25	Sjögren	Sjögren	NNP
cord-278081-tk7vn1v1	55	26	's	's	POS
cord-278081-tk7vn1v1	55	27	syndrome	syndrome	NN
cord-278081-tk7vn1v1	55	28	(	(	-LRB-
cord-278081-tk7vn1v1	55	29	SjS	SjS	NNP
cord-278081-tk7vn1v1	55	30	)	)	-RRB-
cord-278081-tk7vn1v1	55	31	(	(	-LRB-
cord-278081-tk7vn1v1	55	32	44	44	CD
cord-278081-tk7vn1v1	55	33	)	)	-RRB-
cord-278081-tk7vn1v1	55	34	and	and	CC
cord-278081-tk7vn1v1	55	35	prior	prior	JJ
cord-278081-tk7vn1v1	55	36	EBV	EBV	NNP
cord-278081-tk7vn1v1	55	37	infection	infection	NN
cord-278081-tk7vn1v1	55	38	,	,	,
cord-278081-tk7vn1v1	55	39	as	as	IN
cord-278081-tk7vn1v1	55	40	indicated	indicate	VBN
cord-278081-tk7vn1v1	55	41	by	by	IN
cord-278081-tk7vn1v1	55	42	sero	sero	NN
cord-278081-tk7vn1v1	55	43	-	-	HYPH
cord-278081-tk7vn1v1	55	44	positivity	positivity	NN
cord-278081-tk7vn1v1	55	45	for	for	IN
cord-278081-tk7vn1v1	55	46	EBV	EBV	NNP
cord-278081-tk7vn1v1	55	47	antigens	antigen	NNS
cord-278081-tk7vn1v1	55	48	,	,	,
cord-278081-tk7vn1v1	55	49	is	be	VBZ
cord-278081-tk7vn1v1	55	50	observed	observe	VBN
cord-278081-tk7vn1v1	55	51	in	in	IN
cord-278081-tk7vn1v1	55	52	94.2	94.2	CD
cord-278081-tk7vn1v1	55	53	%	%	NN
cord-278081-tk7vn1v1	55	54	of	of	IN
cord-278081-tk7vn1v1	55	55	controls	control	NNS
cord-278081-tk7vn1v1	55	56	and	and	CC
cord-278081-tk7vn1v1	55	57	99.5	99.5	CD
cord-278081-tk7vn1v1	55	58	%	%	NN
cord-278081-tk7vn1v1	55	59	of	of	IN
cord-278081-tk7vn1v1	55	60	MS	MS	NNP
cord-278081-tk7vn1v1	55	61	patients	patient	NNS
cord-278081-tk7vn1v1	55	62	(	(	-LRB-
cord-278081-tk7vn1v1	55	63	45	45	CD
cord-278081-tk7vn1v1	55	64	)	)	-RRB-
cord-278081-tk7vn1v1	55	65	.	.	.
cord-278081-tk7vn1v1	56	1	In	in	IN
cord-278081-tk7vn1v1	56	2	addition	addition	NN
cord-278081-tk7vn1v1	56	3	,	,	,
cord-278081-tk7vn1v1	56	4	EBV	EBV	NNP
cord-278081-tk7vn1v1	56	5	(	(	-LRB-
cord-278081-tk7vn1v1	56	6	human	human	JJ
cord-278081-tk7vn1v1	56	7	gammaherpesvirus	gammaherpesvirus	NNP
cord-278081-tk7vn1v1	56	8	4	4	CD
cord-278081-tk7vn1v1	56	9	,	,	,
cord-278081-tk7vn1v1	56	10	HHV-4	HHV-4	NNP
cord-278081-tk7vn1v1	56	11	)	)	-RRB-
cord-278081-tk7vn1v1	56	12	is	be	VBZ
cord-278081-tk7vn1v1	56	13	representative	representative	NN
cord-278081-tk7vn1v1	56	14	of	of	IN
cord-278081-tk7vn1v1	56	15	several	several	JJ
cord-278081-tk7vn1v1	56	16	herpes	herpes	NN
cord-278081-tk7vn1v1	56	17	viruses	virus	NNS
cord-278081-tk7vn1v1	56	18	that	that	WDT
cord-278081-tk7vn1v1	56	19	have	have	VBP
cord-278081-tk7vn1v1	56	20	shown	show	VBN
cord-278081-tk7vn1v1	56	21	associations	association	NNS
cord-278081-tk7vn1v1	56	22	with	with	IN
cord-278081-tk7vn1v1	56	23	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	56	24	diseases	disease	NNS
cord-278081-tk7vn1v1	56	25	.	.	.
cord-278081-tk7vn1v1	57	1	Therefore	therefore	RB
cord-278081-tk7vn1v1	57	2	,	,	,
cord-278081-tk7vn1v1	57	3	based	base	VBN
cord-278081-tk7vn1v1	57	4	on	on	IN
cord-278081-tk7vn1v1	57	5	current	current	JJ
cord-278081-tk7vn1v1	57	6	knowledge	knowledge	NN
cord-278081-tk7vn1v1	57	7	,	,	,
cord-278081-tk7vn1v1	57	8	EBV	EBV	NNP
cord-278081-tk7vn1v1	57	9	is	be	VBZ
cord-278081-tk7vn1v1	57	10	most	most	RBS
cord-278081-tk7vn1v1	57	11	useful	useful	JJ
cord-278081-tk7vn1v1	57	12	for	for	IN
cord-278081-tk7vn1v1	57	13	describing	describe	VBG
cord-278081-tk7vn1v1	57	14	possible	possible	JJ
cord-278081-tk7vn1v1	57	15	viral	viral	JJ
cord-278081-tk7vn1v1	57	16	involvement	involvement	NN
cord-278081-tk7vn1v1	57	17	in	in	IN
cord-278081-tk7vn1v1	57	18	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	57	19	diseases	disease	NNS
cord-278081-tk7vn1v1	57	20	in	in	IN
cord-278081-tk7vn1v1	57	21	general	general	JJ
cord-278081-tk7vn1v1	57	22	.	.	.
cord-278081-tk7vn1v1	58	1	One	one	CD
cord-278081-tk7vn1v1	58	2	way	way	NN
cord-278081-tk7vn1v1	58	3	in	in	IN
cord-278081-tk7vn1v1	58	4	which	which	WDT
cord-278081-tk7vn1v1	58	5	a	a	DT
cord-278081-tk7vn1v1	58	6	viral	viral	JJ
cord-278081-tk7vn1v1	58	7	infection	infection	NN
cord-278081-tk7vn1v1	58	8	could	could	MD
cord-278081-tk7vn1v1	58	9	provoke	provoke	VB
cord-278081-tk7vn1v1	58	10	an	an	DT
cord-278081-tk7vn1v1	58	11	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	58	12	reaction	reaction	NN
cord-278081-tk7vn1v1	58	13	is	be	VBZ
cord-278081-tk7vn1v1	58	14	by	by	IN
cord-278081-tk7vn1v1	58	15	disrupting	disrupt	VBG
cord-278081-tk7vn1v1	58	16	the	the	DT
cord-278081-tk7vn1v1	58	17	host	host	NN
cord-278081-tk7vn1v1	58	18	cell	cell	NN
cord-278081-tk7vn1v1	58	19	's	's	POS
cord-278081-tk7vn1v1	58	20	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	58	21	control	control	NN
cord-278081-tk7vn1v1	58	22	during	during	IN
cord-278081-tk7vn1v1	58	23	a	a	DT
cord-278081-tk7vn1v1	58	24	particularly	particularly	RB
cord-278081-tk7vn1v1	58	25	strong	strong	JJ
cord-278081-tk7vn1v1	58	26	cellular	cellular	JJ
cord-278081-tk7vn1v1	58	27	stress	stress	NN
cord-278081-tk7vn1v1	58	28	response	response	NN
cord-278081-tk7vn1v1	58	29	to	to	IN
cord-278081-tk7vn1v1	58	30	the	the	DT
cord-278081-tk7vn1v1	58	31	viral	viral	JJ
cord-278081-tk7vn1v1	58	32	activity	activity	NN
cord-278081-tk7vn1v1	58	33	leading	lead	VBG
cord-278081-tk7vn1v1	58	34	to	to	IN
cord-278081-tk7vn1v1	58	35	expression	expression	NN
cord-278081-tk7vn1v1	58	36	of	of	IN
cord-278081-tk7vn1v1	58	37	previously	previously	RB
cord-278081-tk7vn1v1	58	38	sequestered	sequester	VBN
cord-278081-tk7vn1v1	58	39	gene	gene	NN
cord-278081-tk7vn1v1	58	40	alleles	allele	NNS
cord-278081-tk7vn1v1	58	41	.	.	.
cord-278081-tk7vn1v1	59	1	Expression	expression	NN
cord-278081-tk7vn1v1	59	2	from	from	IN
cord-278081-tk7vn1v1	59	3	those	those	DT
cord-278081-tk7vn1v1	59	4	newly	newly	RB
cord-278081-tk7vn1v1	59	5	opened	open	VBN
cord-278081-tk7vn1v1	59	6	sites	site	NNS
cord-278081-tk7vn1v1	59	7	could	could	MD
cord-278081-tk7vn1v1	59	8	lead	lead	VB
cord-278081-tk7vn1v1	59	9	to	to	IN
cord-278081-tk7vn1v1	59	10	imbalance	imbalance	NN
cord-278081-tk7vn1v1	59	11	in	in	IN
cord-278081-tk7vn1v1	59	12	the	the	DT
cord-278081-tk7vn1v1	59	13	protein	protein	NN
cord-278081-tk7vn1v1	59	14	and	and	CC
cord-278081-tk7vn1v1	59	15	RNA	RNA	NNP
cord-278081-tk7vn1v1	59	16	products	product	NNS
cord-278081-tk7vn1v1	59	17	.	.	.
cord-278081-tk7vn1v1	60	1	The	the	DT
cord-278081-tk7vn1v1	60	2	female	female	JJ
cord-278081-tk7vn1v1	60	3	predominance	predominance	NN
cord-278081-tk7vn1v1	60	4	of	of	IN
cord-278081-tk7vn1v1	60	5	many	many	JJ
cord-278081-tk7vn1v1	60	6	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	60	7	diseases	disease	NNS
cord-278081-tk7vn1v1	60	8	suggests	suggest	VBZ
cord-278081-tk7vn1v1	60	9	that	that	IN
cord-278081-tk7vn1v1	60	10	the	the	DT
cord-278081-tk7vn1v1	60	11	X	x	NN
cord-278081-tk7vn1v1	60	12	chromosome	chromosome	NN
cord-278081-tk7vn1v1	60	13	and	and	CC
cord-278081-tk7vn1v1	60	14	possibly	possibly	RB
cord-278081-tk7vn1v1	60	15	disruption	disruption	NN
cord-278081-tk7vn1v1	60	16	of	of	IN
cord-278081-tk7vn1v1	60	17	the	the	DT
cord-278081-tk7vn1v1	60	18	inactive	inactive	JJ
cord-278081-tk7vn1v1	60	19	X	x	NN
cord-278081-tk7vn1v1	60	20	chromosome	chromosome	NN
cord-278081-tk7vn1v1	60	21	,	,	,
cord-278081-tk7vn1v1	60	22	a	a	DT
cord-278081-tk7vn1v1	60	23	major	major	JJ
cord-278081-tk7vn1v1	60	24	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	60	25	structure	structure	NN
cord-278081-tk7vn1v1	60	26	in	in	IN
cord-278081-tk7vn1v1	60	27	the	the	DT
cord-278081-tk7vn1v1	60	28	cell	cell	NN
cord-278081-tk7vn1v1	60	29	,	,	,
cord-278081-tk7vn1v1	60	30	could	could	MD
cord-278081-tk7vn1v1	60	31	be	be	VB
cord-278081-tk7vn1v1	60	32	of	of	IN
cord-278081-tk7vn1v1	60	33	significance	significance	NN
cord-278081-tk7vn1v1	60	34	in	in	IN
cord-278081-tk7vn1v1	60	35	such	such	PDT
cord-278081-tk7vn1v1	60	36	a	a	DT
cord-278081-tk7vn1v1	60	37	scenario	scenario	NN
cord-278081-tk7vn1v1	60	38	of	of	IN
cord-278081-tk7vn1v1	60	39	viral	viral	JJ
cord-278081-tk7vn1v1	60	40	disruption	disruption	NN
cord-278081-tk7vn1v1	60	41	of	of	IN
cord-278081-tk7vn1v1	60	42	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	60	43	control	control	NN
cord-278081-tk7vn1v1	60	44	(	(	-LRB-
cord-278081-tk7vn1v1	60	45	1	1	CD
cord-278081-tk7vn1v1	60	46	,	,	,
cord-278081-tk7vn1v1	60	47	3	3	CD
cord-278081-tk7vn1v1	60	48	)	)	-RRB-
cord-278081-tk7vn1v1	60	49	.	.	.
cord-278081-tk7vn1v1	61	1	One	one	CD
cord-278081-tk7vn1v1	61	2	point	point	NN
cord-278081-tk7vn1v1	61	3	of	of	IN
cord-278081-tk7vn1v1	61	4	concern	concern	NN
cord-278081-tk7vn1v1	61	5	is	be	VBZ
cord-278081-tk7vn1v1	61	6	fragile	fragile	JJ
cord-278081-tk7vn1v1	61	7	sites	site	NNS
cord-278081-tk7vn1v1	61	8	,	,	,
cord-278081-tk7vn1v1	61	9	which	which	WDT
cord-278081-tk7vn1v1	61	10	are	be	VBP
cord-278081-tk7vn1v1	61	11	particularly	particularly	RB
cord-278081-tk7vn1v1	61	12	susceptible	susceptible	JJ
cord-278081-tk7vn1v1	61	13	to	to	IN
cord-278081-tk7vn1v1	61	14	viral	viral	JJ
cord-278081-tk7vn1v1	61	15	insertion	insertion	NN
cord-278081-tk7vn1v1	61	16	and	and	CC
cord-278081-tk7vn1v1	61	17	DNA	dna	NN
cord-278081-tk7vn1v1	61	18	breaks	break	NNS
cord-278081-tk7vn1v1	61	19	.	.	.
cord-278081-tk7vn1v1	62	1	Fragile	fragile	JJ
cord-278081-tk7vn1v1	62	2	sites	site	NNS
cord-278081-tk7vn1v1	62	3	can	can	MD
cord-278081-tk7vn1v1	62	4	be	be	VB
cord-278081-tk7vn1v1	62	5	hundreds	hundred	NNS
cord-278081-tk7vn1v1	62	6	of	of	IN
cord-278081-tk7vn1v1	62	7	thousands	thousand	NNS
cord-278081-tk7vn1v1	62	8	,	,	,
cord-278081-tk7vn1v1	62	9	even	even	RB
cord-278081-tk7vn1v1	62	10	millions	million	NNS
cord-278081-tk7vn1v1	62	11	of	of	IN
cord-278081-tk7vn1v1	62	12	base	base	NN
cord-278081-tk7vn1v1	62	13	pairs	pair	NNS
cord-278081-tk7vn1v1	62	14	in	in	IN
cord-278081-tk7vn1v1	62	15	length	length	NN
cord-278081-tk7vn1v1	62	16	.	.	.
cord-278081-tk7vn1v1	63	1	The	the	DT
cord-278081-tk7vn1v1	63	2	X	x	NN
cord-278081-tk7vn1v1	63	3	chromosome	chromosome	NN
cord-278081-tk7vn1v1	63	4	has	have	VBZ
cord-278081-tk7vn1v1	63	5	four	four	CD
cord-278081-tk7vn1v1	63	6	major	major	JJ
cord-278081-tk7vn1v1	63	7	fragile	fragile	JJ
cord-278081-tk7vn1v1	63	8	sites	site	NNS
cord-278081-tk7vn1v1	63	9	(	(	-LRB-
cord-278081-tk7vn1v1	63	10	FRAXA	fraxa	NN
cord-278081-tk7vn1v1	63	11	at	at	IN
cord-278081-tk7vn1v1	64	1	Xq28	Xq28	NNP
cord-278081-tk7vn1v1	64	2	;	;	:
cord-278081-tk7vn1v1	64	3	FRAXB	FRAXB	NNP
cord-278081-tk7vn1v1	64	4	at	at	IN
cord-278081-tk7vn1v1	64	5	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	64	6	;	;	:
cord-278081-tk7vn1v1	64	7	FRAXC	FRAXC	NNP
cord-278081-tk7vn1v1	64	8	at	at	IN
cord-278081-tk7vn1v1	64	9	Xq22	xq22	RB
cord-278081-tk7vn1v1	64	10	;	;	:
cord-278081-tk7vn1v1	64	11	and	and	CC
cord-278081-tk7vn1v1	64	12	FRAXD	fraxd	NN
cord-278081-tk7vn1v1	64	13	at	at	IN
cord-278081-tk7vn1v1	64	14	Xq27	Xq27	NNS
cord-278081-tk7vn1v1	64	15	)	)	-RRB-
cord-278081-tk7vn1v1	65	1	(	(	-LRB-
cord-278081-tk7vn1v1	65	2	1	1	CD
cord-278081-tk7vn1v1	65	3	,	,	,
cord-278081-tk7vn1v1	65	4	46	46	CD
cord-278081-tk7vn1v1	65	5	)	)	-RRB-
cord-278081-tk7vn1v1	65	6	.	.	.
cord-278081-tk7vn1v1	66	1	Reactivation	reactivation	NN
cord-278081-tk7vn1v1	66	2	of	of	IN
cord-278081-tk7vn1v1	66	3	part	part	NN
cord-278081-tk7vn1v1	66	4	or	or	CC
cord-278081-tk7vn1v1	66	5	all	all	DT
cord-278081-tk7vn1v1	66	6	of	of	IN
cord-278081-tk7vn1v1	66	7	the	the	DT
cord-278081-tk7vn1v1	66	8	inactive	inactive	JJ
cord-278081-tk7vn1v1	66	9	X	x	NN
cord-278081-tk7vn1v1	66	10	chromosome	chromosome	NN
cord-278081-tk7vn1v1	66	11	could	could	MD
cord-278081-tk7vn1v1	66	12	open	open	VB
cord-278081-tk7vn1v1	66	13	these	these	DT
cord-278081-tk7vn1v1	66	14	fragile	fragile	JJ
cord-278081-tk7vn1v1	66	15	sites	site	NNS
cord-278081-tk7vn1v1	66	16	for	for	IN
cord-278081-tk7vn1v1	66	17	expression	expression	NN
cord-278081-tk7vn1v1	66	18	of	of	IN
cord-278081-tk7vn1v1	66	19	hidden	hidden	JJ
cord-278081-tk7vn1v1	66	20	viruses	virus	NNS
cord-278081-tk7vn1v1	66	21	in	in	IN
cord-278081-tk7vn1v1	66	22	the	the	DT
cord-278081-tk7vn1v1	66	23	fragile	fragile	JJ
cord-278081-tk7vn1v1	66	24	sites	site	NNS
cord-278081-tk7vn1v1	66	25	,	,	,
cord-278081-tk7vn1v1	66	26	adding	add	VBG
cord-278081-tk7vn1v1	66	27	to	to	IN
cord-278081-tk7vn1v1	66	28	the	the	DT
cord-278081-tk7vn1v1	66	29	cellular	cellular	JJ
cord-278081-tk7vn1v1	66	30	stress	stress	NN
cord-278081-tk7vn1v1	66	31	.	.	.
cord-278081-tk7vn1v1	67	1	Once	once	RB
cord-278081-tk7vn1v1	67	2	a	a	DT
cord-278081-tk7vn1v1	67	3	virus	virus	NN
cord-278081-tk7vn1v1	67	4	becomes	become	VBZ
cord-278081-tk7vn1v1	67	5	active	active	JJ
cord-278081-tk7vn1v1	67	6	in	in	IN
cord-278081-tk7vn1v1	67	7	a	a	DT
cord-278081-tk7vn1v1	67	8	cell	cell	NN
cord-278081-tk7vn1v1	67	9	,	,	,
cord-278081-tk7vn1v1	67	10	one	one	CD
cord-278081-tk7vn1v1	67	11	of	of	IN
cord-278081-tk7vn1v1	67	12	its	-PRON-	PRP$
cord-278081-tk7vn1v1	67	13	prime	prime	JJ
cord-278081-tk7vn1v1	67	14	targets	target	NNS
cord-278081-tk7vn1v1	67	15	in	in	IN
cord-278081-tk7vn1v1	67	16	taking	take	VBG
cord-278081-tk7vn1v1	67	17	over	over	RP
cord-278081-tk7vn1v1	67	18	the	the	DT
cord-278081-tk7vn1v1	67	19	cell	cell	NN
cord-278081-tk7vn1v1	67	20	is	be	VBZ
cord-278081-tk7vn1v1	67	21	the	the	DT
cord-278081-tk7vn1v1	67	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	67	23	.	.	.
cord-278081-tk7vn1v1	68	1	The	the	DT
cord-278081-tk7vn1v1	68	2	virus	virus	NN
cord-278081-tk7vn1v1	68	3	is	be	VBZ
cord-278081-tk7vn1v1	68	4	dependent	dependent	JJ
cord-278081-tk7vn1v1	68	5	on	on	IN
cord-278081-tk7vn1v1	68	6	the	the	DT
cord-278081-tk7vn1v1	68	7	host	host	NN
cord-278081-tk7vn1v1	68	8	cell	cell	NN
cord-278081-tk7vn1v1	68	9	's	's	POS
cord-278081-tk7vn1v1	68	10	machinery	machinery	NN
cord-278081-tk7vn1v1	68	11	,	,	,
cord-278081-tk7vn1v1	68	12	including	include	VBG
cord-278081-tk7vn1v1	68	13	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	68	14	and	and	CC
cord-278081-tk7vn1v1	68	15	transfer	transfer	NN
cord-278081-tk7vn1v1	68	16	RNAs	rna	NNS
cord-278081-tk7vn1v1	68	17	(	(	-LRB-
cord-278081-tk7vn1v1	68	18	tRNA	tRNA	NNP
cord-278081-tk7vn1v1	68	19	)	)	-RRB-
cord-278081-tk7vn1v1	68	20	,	,	,
cord-278081-tk7vn1v1	68	21	in	in	IN
cord-278081-tk7vn1v1	68	22	order	order	NN
cord-278081-tk7vn1v1	68	23	for	for	IN
cord-278081-tk7vn1v1	68	24	viral	viral	JJ
cord-278081-tk7vn1v1	68	25	proteins	protein	NNS
cord-278081-tk7vn1v1	68	26	to	to	TO
cord-278081-tk7vn1v1	68	27	be	be	VB
cord-278081-tk7vn1v1	68	28	synthesized	synthesize	VBN
cord-278081-tk7vn1v1	68	29	.	.	.
cord-278081-tk7vn1v1	69	1	And	and	CC
cord-278081-tk7vn1v1	69	2	viral	viral	JJ
cord-278081-tk7vn1v1	69	3	RNAs	rna	NNS
cord-278081-tk7vn1v1	69	4	need	need	VBP
cord-278081-tk7vn1v1	69	5	to	to	TO
cord-278081-tk7vn1v1	69	6	be	be	VB
cord-278081-tk7vn1v1	69	7	properly	properly	RB
cord-278081-tk7vn1v1	69	8	folded	fold	VBN
cord-278081-tk7vn1v1	69	9	and	and	CC
cord-278081-tk7vn1v1	69	10	assembled	assemble	VBN
cord-278081-tk7vn1v1	69	11	into	into	IN
cord-278081-tk7vn1v1	69	12	ribonucleoprotein	ribonucleoprotein	NN
cord-278081-tk7vn1v1	69	13	complexes	complex	NNS
cord-278081-tk7vn1v1	69	14	(	(	-LRB-
cord-278081-tk7vn1v1	69	15	RNPs	RNPs	NNP
cord-278081-tk7vn1v1	69	16	)	)	-RRB-
cord-278081-tk7vn1v1	69	17	.	.	.
cord-278081-tk7vn1v1	70	1	RNA	RNA	NNP
cord-278081-tk7vn1v1	70	2	and	and	CC
cord-278081-tk7vn1v1	70	3	RNP	RNP	NNP
cord-278081-tk7vn1v1	70	4	processing	processing	NN
cord-278081-tk7vn1v1	70	5	and	and	CC
cord-278081-tk7vn1v1	70	6	assembly	assembly	NN
cord-278081-tk7vn1v1	70	7	are	be	VBP
cord-278081-tk7vn1v1	70	8	major	major	JJ
cord-278081-tk7vn1v1	70	9	functions	function	NNS
cord-278081-tk7vn1v1	70	10	of	of	IN
cord-278081-tk7vn1v1	70	11	the	the	DT
cord-278081-tk7vn1v1	70	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	70	13	.	.	.
cord-278081-tk7vn1v1	71	1	The	the	DT
cord-278081-tk7vn1v1	71	2	virus	virus	NN
cord-278081-tk7vn1v1	71	3	puts	put	VBZ
cord-278081-tk7vn1v1	71	4	additional	additional	JJ
cord-278081-tk7vn1v1	71	5	demands	demand	NNS
cord-278081-tk7vn1v1	71	6	on	on	IN
cord-278081-tk7vn1v1	71	7	the	the	DT
cord-278081-tk7vn1v1	71	8	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	71	9	functions	function	NNS
cord-278081-tk7vn1v1	71	10	beyond	beyond	IN
cord-278081-tk7vn1v1	71	11	the	the	DT
cord-278081-tk7vn1v1	71	12	host	host	NN
cord-278081-tk7vn1v1	71	13	cell	cell	NN
cord-278081-tk7vn1v1	71	14	's	's	POS
cord-278081-tk7vn1v1	71	15	needs	need	NNS
cord-278081-tk7vn1v1	71	16	and	and	CC
cord-278081-tk7vn1v1	71	17	,	,	,
cord-278081-tk7vn1v1	71	18	since	since	IN
cord-278081-tk7vn1v1	71	19	the	the	DT
cord-278081-tk7vn1v1	71	20	virus	virus	NN
cord-278081-tk7vn1v1	71	21	does	do	VBZ
cord-278081-tk7vn1v1	71	22	not	not	RB
cord-278081-tk7vn1v1	71	23	code	code	VB
cord-278081-tk7vn1v1	71	24	for	for	IN
cord-278081-tk7vn1v1	71	25	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	71	26	and	and	CC
cord-278081-tk7vn1v1	71	27	such	such	JJ
cord-278081-tk7vn1v1	71	28	,	,	,
cord-278081-tk7vn1v1	71	29	the	the	DT
cord-278081-tk7vn1v1	71	30	virus	virus	NN
cord-278081-tk7vn1v1	71	31	needs	need	VBZ
cord-278081-tk7vn1v1	71	32	to	to	TO
cord-278081-tk7vn1v1	71	33	induce	induce	VB
cord-278081-tk7vn1v1	71	34	increased	increase	VBN
cord-278081-tk7vn1v1	71	35	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	71	36	capacity	capacity	NN
cord-278081-tk7vn1v1	71	37	and	and	CC
cord-278081-tk7vn1v1	71	38	activity	activity	NN
cord-278081-tk7vn1v1	71	39	.	.	.
cord-278081-tk7vn1v1	72	1	Localization	localization	NN
cord-278081-tk7vn1v1	72	2	of	of	IN
cord-278081-tk7vn1v1	72	3	viral	viral	JJ
cord-278081-tk7vn1v1	72	4	RNA	RNA	NNP
cord-278081-tk7vn1v1	72	5	and	and	CC
cord-278081-tk7vn1v1	72	6	proteins	protein	NNS
cord-278081-tk7vn1v1	72	7	to	to	IN
cord-278081-tk7vn1v1	72	8	the	the	DT
cord-278081-tk7vn1v1	72	9	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	72	10	takes	take	VBZ
cord-278081-tk7vn1v1	72	11	advantage	advantage	NN
cord-278081-tk7vn1v1	72	12	of	of	IN
cord-278081-tk7vn1v1	72	13	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	72	14	and	and	CC
cord-278081-tk7vn1v1	72	15	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	72	16	localization	localization	NN
cord-278081-tk7vn1v1	72	17	signals	signal	NNS
cord-278081-tk7vn1v1	72	18	(	(	-LRB-
cord-278081-tk7vn1v1	72	19	NoLS	NoLS	NNP
cord-278081-tk7vn1v1	72	20	)	)	-RRB-
cord-278081-tk7vn1v1	72	21	and	and	CC
cord-278081-tk7vn1v1	72	22	chaperones	chaperone	NNS
cord-278081-tk7vn1v1	72	23	.	.	.
cord-278081-tk7vn1v1	73	1	In	in	IN
cord-278081-tk7vn1v1	73	2	the	the	DT
cord-278081-tk7vn1v1	73	3	case	case	NN
cord-278081-tk7vn1v1	73	4	of	of	IN
cord-278081-tk7vn1v1	73	5	viral	viral	JJ
cord-278081-tk7vn1v1	73	6	RNA	RNA	NNP
cord-278081-tk7vn1v1	73	7	transcripts	transcript	NNS
cord-278081-tk7vn1v1	73	8	,	,	,
cord-278081-tk7vn1v1	73	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	73	10	pol	pol	NN
cord-278081-tk7vn1v1	73	11	III	III	NNP
cord-278081-tk7vn1v1	73	12	transcribed	transcribe	VBD
cord-278081-tk7vn1v1	73	13	RNAs	rna	NNS
cord-278081-tk7vn1v1	73	14	bind	bind	VBP
cord-278081-tk7vn1v1	73	15	SSB	SSB	NNP
cord-278081-tk7vn1v1	73	16	/	/	SYM
cord-278081-tk7vn1v1	73	17	La	La	NNP
cord-278081-tk7vn1v1	73	18	and	and	CC
cord-278081-tk7vn1v1	73	19	SSA	SSA	NNP
cord-278081-tk7vn1v1	73	20	/	/	SYM
cord-278081-tk7vn1v1	73	21	Ro	Ro	NNP
cord-278081-tk7vn1v1	73	22	which	which	WDT
cord-278081-tk7vn1v1	73	23	assist	assist	VBP
cord-278081-tk7vn1v1	73	24	in	in	IN
cord-278081-tk7vn1v1	73	25	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	73	26	entry	entry	NN
cord-278081-tk7vn1v1	73	27	and	and	CC
cord-278081-tk7vn1v1	73	28	processing	processing	NN
cord-278081-tk7vn1v1	73	29	along	along	RP
cord-278081-tk7vn1v1	73	30	with	with	IN
cord-278081-tk7vn1v1	73	31	any	any	DT
cord-278081-tk7vn1v1	73	32	required	required	JJ
cord-278081-tk7vn1v1	73	33	refolding	refolding	NN
cord-278081-tk7vn1v1	73	34	.	.	.
cord-278081-tk7vn1v1	74	1	For	for	IN
cord-278081-tk7vn1v1	74	2	viral	viral	JJ
cord-278081-tk7vn1v1	74	3	proteins	protein	NNS
cord-278081-tk7vn1v1	74	4	,	,	,
cord-278081-tk7vn1v1	74	5	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	74	6	localization	localization	NN
cord-278081-tk7vn1v1	74	7	signals	signal	NNS
cord-278081-tk7vn1v1	74	8	(	(	-LRB-
cord-278081-tk7vn1v1	74	9	NLS	NLS	NNP
cord-278081-tk7vn1v1	74	10	)	)	-RRB-
cord-278081-tk7vn1v1	74	11	,	,	,
cord-278081-tk7vn1v1	74	12	which	which	WDT
cord-278081-tk7vn1v1	74	13	are	be	VBP
cord-278081-tk7vn1v1	74	14	sequences	sequence	NNS
cord-278081-tk7vn1v1	74	15	of	of	IN
cord-278081-tk7vn1v1	74	16	basic	basic	JJ
cord-278081-tk7vn1v1	74	17	amino	amino	JJ
cord-278081-tk7vn1v1	74	18	acids	acid	NNS
cord-278081-tk7vn1v1	74	19	,	,	,
cord-278081-tk7vn1v1	74	20	and	and	CC
cord-278081-tk7vn1v1	74	21	NoLS	nol	NNS
cord-278081-tk7vn1v1	74	22	are	be	VBP
cord-278081-tk7vn1v1	74	23	used	use	VBN
cord-278081-tk7vn1v1	74	24	but	but	CC
cord-278081-tk7vn1v1	74	25	,	,	,
cord-278081-tk7vn1v1	74	26	since	since	IN
cord-278081-tk7vn1v1	74	27	these	these	DT
cord-278081-tk7vn1v1	74	28	signals	signal	NNS
cord-278081-tk7vn1v1	74	29	are	be	VBP
cord-278081-tk7vn1v1	74	30	frequently	frequently	RB
cord-278081-tk7vn1v1	74	31	closely	closely	RB
cord-278081-tk7vn1v1	74	32	positioned	position	VBN
cord-278081-tk7vn1v1	74	33	,	,	,
cord-278081-tk7vn1v1	74	34	it	-PRON-	PRP
cord-278081-tk7vn1v1	74	35	has	have	VBZ
cord-278081-tk7vn1v1	74	36	been	be	VBN
cord-278081-tk7vn1v1	74	37	difficult	difficult	JJ
cord-278081-tk7vn1v1	74	38	to	to	TO
cord-278081-tk7vn1v1	74	39	decipher	decipher	VB
cord-278081-tk7vn1v1	74	40	the	the	DT
cord-278081-tk7vn1v1	74	41	NoLS	nol	NNS
cord-278081-tk7vn1v1	74	42	from	from	IN
cord-278081-tk7vn1v1	74	43	the	the	DT
cord-278081-tk7vn1v1	74	44	more	more	RBR
cord-278081-tk7vn1v1	74	45	recognizable	recognizable	JJ
cord-278081-tk7vn1v1	74	46	NLS	nls	NN
cord-278081-tk7vn1v1	74	47	(	(	-LRB-
cord-278081-tk7vn1v1	74	48	47	47	CD
cord-278081-tk7vn1v1	74	49	)	)	-RRB-
cord-278081-tk7vn1v1	74	50	.	.	.
cord-278081-tk7vn1v1	75	1	Some	some	DT
cord-278081-tk7vn1v1	75	2	progress	progress	NN
cord-278081-tk7vn1v1	75	3	has	have	VBZ
cord-278081-tk7vn1v1	75	4	been	be	VBN
cord-278081-tk7vn1v1	75	5	made	make	VBN
cord-278081-tk7vn1v1	75	6	in	in	IN
cord-278081-tk7vn1v1	75	7	determining	determine	VBG
cord-278081-tk7vn1v1	75	8	NoLS	NoLS	NNP
cord-278081-tk7vn1v1	75	9	,	,	,
cord-278081-tk7vn1v1	75	10	such	such	JJ
cord-278081-tk7vn1v1	75	11	as	as	IN
cord-278081-tk7vn1v1	75	12	for	for	IN
cord-278081-tk7vn1v1	75	13	the	the	DT
cord-278081-tk7vn1v1	75	14	adeno	adeno	NN
cord-278081-tk7vn1v1	75	15	-	-	HYPH
cord-278081-tk7vn1v1	75	16	associated	associate	VBN
cord-278081-tk7vn1v1	75	17	virus	virus	NN
cord-278081-tk7vn1v1	75	18	serotype	serotype	NN
cord-278081-tk7vn1v1	75	19	2	2	CD
cord-278081-tk7vn1v1	75	20	assembly	assembly	NN
cord-278081-tk7vn1v1	75	21	activating	activate	VBG
cord-278081-tk7vn1v1	75	22	protein	protein	NN
cord-278081-tk7vn1v1	75	23	(	(	-LRB-
cord-278081-tk7vn1v1	75	24	48	48	CD
cord-278081-tk7vn1v1	75	25	)	)	-RRB-
cord-278081-tk7vn1v1	75	26	,	,	,
cord-278081-tk7vn1v1	75	27	and	and	CC
cord-278081-tk7vn1v1	75	28	for	for	IN
cord-278081-tk7vn1v1	75	29	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	75	30	retention	retention	NN
cord-278081-tk7vn1v1	75	31	signals	signal	NNS
cord-278081-tk7vn1v1	75	32	,	,	,
cord-278081-tk7vn1v1	75	33	such	such	JJ
cord-278081-tk7vn1v1	75	34	as	as	IN
cord-278081-tk7vn1v1	75	35	found	find	VBN
cord-278081-tk7vn1v1	75	36	in	in	IN
cord-278081-tk7vn1v1	75	37	coronavirus	coronavirus	NN
cord-278081-tk7vn1v1	75	38	nucleocapsid	nucleocapsid	NN
cord-278081-tk7vn1v1	75	39	proteins	protein	NNS
cord-278081-tk7vn1v1	75	40	(	(	-LRB-
cord-278081-tk7vn1v1	75	41	49	49	CD
cord-278081-tk7vn1v1	75	42	)	)	-RRB-
cord-278081-tk7vn1v1	75	43	.	.	.
cord-278081-tk7vn1v1	76	1	tHe	the	DT
cord-278081-tk7vn1v1	76	2	nUCLeoLUs	nUCLeoLUs	NNP
cord-278081-tk7vn1v1	76	3	-	-	HYPH
cord-278081-tk7vn1v1	76	4	strUCtUre	strUCtUre	NNP
cord-278081-tk7vn1v1	76	5	,	,	,
cord-278081-tk7vn1v1	76	6	FUnCtion	FUnCtion	NNP
cord-278081-tk7vn1v1	76	7	,	,	,
cord-278081-tk7vn1v1	76	8	and	and	CC
cord-278081-tk7vn1v1	76	9	dynaMiCs	dynaMiCs	NNP
cord-278081-tk7vn1v1	77	1	The	the	DT
cord-278081-tk7vn1v1	77	2	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	77	3	[	[	-LRB-
cord-278081-tk7vn1v1	77	4	reviewed	review	VBN
cord-278081-tk7vn1v1	77	5	in	in	IN
cord-278081-tk7vn1v1	77	6	Ref	Ref	NNP
cord-278081-tk7vn1v1	77	7	.	.	.
cord-278081-tk7vn1v1	78	1	(	(	-LRB-
cord-278081-tk7vn1v1	78	2	50	50	CD
cord-278081-tk7vn1v1	78	3	)	)	-RRB-
cord-278081-tk7vn1v1	78	4	(	(	-LRB-
cord-278081-tk7vn1v1	78	5	51	51	CD
cord-278081-tk7vn1v1	78	6	)	)	-RRB-
cord-278081-tk7vn1v1	79	1	(	(	-LRB-
cord-278081-tk7vn1v1	79	2	52	52	CD
cord-278081-tk7vn1v1	79	3	)	)	-RRB-
cord-278081-tk7vn1v1	80	1	(	(	-LRB-
cord-278081-tk7vn1v1	80	2	53	53	CD
cord-278081-tk7vn1v1	80	3	)	)	-RRB-
cord-278081-tk7vn1v1	81	1	(	(	-LRB-
cord-278081-tk7vn1v1	81	2	54	54	CD
cord-278081-tk7vn1v1	81	3	)	)	-RRB-
cord-278081-tk7vn1v1	81	4	]	]	-RRB-
cord-278081-tk7vn1v1	81	5	is	be	VBZ
cord-278081-tk7vn1v1	81	6	a	a	DT
cord-278081-tk7vn1v1	81	7	prominent	prominent	JJ
cord-278081-tk7vn1v1	81	8	feature	feature	NN
cord-278081-tk7vn1v1	81	9	in	in	IN
cord-278081-tk7vn1v1	81	10	the	the	DT
cord-278081-tk7vn1v1	81	11	nucleus	nucleus	NN
cord-278081-tk7vn1v1	81	12	,	,	,
cord-278081-tk7vn1v1	81	13	appearing	appear	VBG
cord-278081-tk7vn1v1	81	14	as	as	IN
cord-278081-tk7vn1v1	81	15	a	a	DT
cord-278081-tk7vn1v1	81	16	vacant	vacant	JJ
cord-278081-tk7vn1v1	81	17	area	area	NN
cord-278081-tk7vn1v1	81	18	when	when	WRB
cord-278081-tk7vn1v1	81	19	imaging	image	VBG
cord-278081-tk7vn1v1	81	20	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	81	21	DNA	dna	NN
cord-278081-tk7vn1v1	81	22	content	content	NN
cord-278081-tk7vn1v1	81	23	.	.	.
cord-278081-tk7vn1v1	82	1	There	there	EX
cord-278081-tk7vn1v1	82	2	is	be	VBZ
cord-278081-tk7vn1v1	82	3	,	,	,
cord-278081-tk7vn1v1	82	4	in	in	IN
cord-278081-tk7vn1v1	82	5	fact	fact	NN
cord-278081-tk7vn1v1	82	6	,	,	,
cord-278081-tk7vn1v1	82	7	some	some	DT
cord-278081-tk7vn1v1	82	8	DNA	dna	NN
cord-278081-tk7vn1v1	82	9	in	in	IN
cord-278081-tk7vn1v1	82	10	the	the	DT
cord-278081-tk7vn1v1	82	11	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	82	12	.	.	.
cord-278081-tk7vn1v1	83	1	As	as	RB
cord-278081-tk7vn1v1	83	2	far	far	RB
cord-278081-tk7vn1v1	83	3	as	as	IN
cord-278081-tk7vn1v1	83	4	active	active	JJ
cord-278081-tk7vn1v1	83	5	DNA	dna	NN
cord-278081-tk7vn1v1	83	6	in	in	IN
cord-278081-tk7vn1v1	83	7	the	the	DT
cord-278081-tk7vn1v1	83	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	83	9	,	,	,
cord-278081-tk7vn1v1	83	10	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	83	11	associate	associate	VBP
cord-278081-tk7vn1v1	83	12	primarily	primarily	RB
cord-278081-tk7vn1v1	83	13	with	with	IN
cord-278081-tk7vn1v1	83	14	repetitive	repetitive	JJ
cord-278081-tk7vn1v1	83	15	copies	copy	NNS
cord-278081-tk7vn1v1	83	16	of	of	IN
cord-278081-tk7vn1v1	83	17	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	83	18	DNA	dna	NN
cord-278081-tk7vn1v1	83	19	(	(	-LRB-
cord-278081-tk7vn1v1	83	20	rDNA	rDNA	NNP
cord-278081-tk7vn1v1	83	21	)	)	-RRB-
cord-278081-tk7vn1v1	83	22	genes	gene	NNS
cord-278081-tk7vn1v1	83	23	expressing	express	VBG
cord-278081-tk7vn1v1	83	24	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	83	25	RNAs	rna	NNS
cord-278081-tk7vn1v1	83	26	from	from	IN
cord-278081-tk7vn1v1	83	27	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	83	28	organizing	organize	VBG
cord-278081-tk7vn1v1	83	29	regions	region	NNS
cord-278081-tk7vn1v1	83	30	(	(	-LRB-
cord-278081-tk7vn1v1	83	31	NORs	NORs	NNP
cord-278081-tk7vn1v1	83	32	)	)	-RRB-
cord-278081-tk7vn1v1	83	33	which	which	WDT
cord-278081-tk7vn1v1	83	34	are	be	VBP
cord-278081-tk7vn1v1	83	35	located	locate	VBN
cord-278081-tk7vn1v1	83	36	on	on	IN
cord-278081-tk7vn1v1	83	37	the	the	DT
cord-278081-tk7vn1v1	83	38	acrocentric	acrocentric	NNP
cord-278081-tk7vn1v1	83	39	autosomes	autosomes	NNP
cord-278081-tk7vn1v1	83	40	13	13	CD
cord-278081-tk7vn1v1	83	41	,	,	,
cord-278081-tk7vn1v1	83	42	14	14	CD
cord-278081-tk7vn1v1	83	43	,	,	,
cord-278081-tk7vn1v1	83	44	15	15	CD
cord-278081-tk7vn1v1	83	45	,	,	,
cord-278081-tk7vn1v1	83	46	21	21	CD
cord-278081-tk7vn1v1	83	47	,	,	,
cord-278081-tk7vn1v1	83	48	and	and	CC
cord-278081-tk7vn1v1	83	49	22	22	CD
cord-278081-tk7vn1v1	83	50	.	.	.
cord-278081-tk7vn1v1	84	1	Other	other	JJ
cord-278081-tk7vn1v1	84	2	DNA	dna	NN
cord-278081-tk7vn1v1	84	3	sequences	sequence	NNS
cord-278081-tk7vn1v1	84	4	may	may	MD
cord-278081-tk7vn1v1	84	5	be	be	VB
cord-278081-tk7vn1v1	84	6	involved	involve	VBN
cord-278081-tk7vn1v1	84	7	at	at	IN
cord-278081-tk7vn1v1	84	8	the	the	DT
cord-278081-tk7vn1v1	84	9	periphery	periphery	NN
cord-278081-tk7vn1v1	84	10	of	of	IN
cord-278081-tk7vn1v1	84	11	the	the	DT
cord-278081-tk7vn1v1	84	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	84	13	transiently	transiently	RB
cord-278081-tk7vn1v1	84	14	,	,	,
cord-278081-tk7vn1v1	84	15	such	such	JJ
cord-278081-tk7vn1v1	84	16	as	as	IN
cord-278081-tk7vn1v1	84	17	in	in	IN
cord-278081-tk7vn1v1	84	18	repair	repair	NN
cord-278081-tk7vn1v1	84	19	of	of	IN
cord-278081-tk7vn1v1	84	20	breaks	break	NNS
cord-278081-tk7vn1v1	84	21	in	in	IN
cord-278081-tk7vn1v1	84	22	DNA	dna	NN
cord-278081-tk7vn1v1	84	23	near	near	IN
cord-278081-tk7vn1v1	84	24	the	the	DT
cord-278081-tk7vn1v1	84	25	rDNA	rdna	JJ
cord-278081-tk7vn1v1	84	26	genes	gene	NNS
cord-278081-tk7vn1v1	84	27	.	.	.
cord-278081-tk7vn1v1	85	1	A	a	DT
cord-278081-tk7vn1v1	85	2	role	role	NN
cord-278081-tk7vn1v1	85	3	in	in	IN
cord-278081-tk7vn1v1	85	4	DNA	dna	NN
cord-278081-tk7vn1v1	85	5	repair	repair	NN
cord-278081-tk7vn1v1	85	6	in	in	IN
cord-278081-tk7vn1v1	85	7	general	general	JJ
cord-278081-tk7vn1v1	85	8	is	be	VBZ
cord-278081-tk7vn1v1	85	9	emerging	emerge	VBG
cord-278081-tk7vn1v1	85	10	for	for	IN
cord-278081-tk7vn1v1	85	11	the	the	DT
cord-278081-tk7vn1v1	85	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	85	13	since	since	IN
cord-278081-tk7vn1v1	85	14	many	many	JJ
cord-278081-tk7vn1v1	85	15	proteins	protein	NNS
cord-278081-tk7vn1v1	85	16	involved	involve	VBN
cord-278081-tk7vn1v1	85	17	in	in	IN
cord-278081-tk7vn1v1	85	18	DNA	dna	NN
cord-278081-tk7vn1v1	85	19	repair	repair	NN
cord-278081-tk7vn1v1	85	20	have	have	VBP
cord-278081-tk7vn1v1	85	21	associations	association	NNS
cord-278081-tk7vn1v1	85	22	with	with	IN
cord-278081-tk7vn1v1	85	23	the	the	DT
cord-278081-tk7vn1v1	85	24	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	85	25	(	(	-LRB-
cord-278081-tk7vn1v1	85	26	55	55	CD
cord-278081-tk7vn1v1	85	27	)	)	-RRB-
cord-278081-tk7vn1v1	85	28	.	.	.
cord-278081-tk7vn1v1	86	1	Further	further	RB
cord-278081-tk7vn1v1	86	2	,	,	,
cord-278081-tk7vn1v1	86	3	centromeric	centromeric	JJ
cord-278081-tk7vn1v1	86	4	DNA	DNA	NNP
cord-278081-tk7vn1v1	86	5	is	be	VBZ
cord-278081-tk7vn1v1	86	6	associated	associate	VBN
cord-278081-tk7vn1v1	86	7	with	with	IN
cord-278081-tk7vn1v1	86	8	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	86	9	as	as	IN
cord-278081-tk7vn1v1	86	10	part	part	NN
cord-278081-tk7vn1v1	86	11	of	of	IN
cord-278081-tk7vn1v1	86	12	the	the	DT
cord-278081-tk7vn1v1	86	13	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	86	14	regulation	regulation	NN
cord-278081-tk7vn1v1	86	15	of	of	IN
cord-278081-tk7vn1v1	86	16	the	the	DT
cord-278081-tk7vn1v1	86	17	cell	cell	NN
cord-278081-tk7vn1v1	86	18	cycle	cycle	NN
cord-278081-tk7vn1v1	86	19	(	(	-LRB-
cord-278081-tk7vn1v1	86	20	56	56	CD
cord-278081-tk7vn1v1	86	21	)	)	-RRB-
cord-278081-tk7vn1v1	86	22	.	.	.
cord-278081-tk7vn1v1	87	1	The	the	DT
cord-278081-tk7vn1v1	87	2	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	87	3	does	do	VBZ
cord-278081-tk7vn1v1	87	4	not	not	RB
cord-278081-tk7vn1v1	87	5	have	have	VB
cord-278081-tk7vn1v1	87	6	a	a	DT
cord-278081-tk7vn1v1	87	7	membrane	membrane	NN
cord-278081-tk7vn1v1	87	8	defining	define	VBG
cord-278081-tk7vn1v1	87	9	its	-PRON-	PRP$
cord-278081-tk7vn1v1	87	10	structure	structure	NN
cord-278081-tk7vn1v1	87	11	but	but	CC
cord-278081-tk7vn1v1	87	12	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	87	13	are	be	VBP
cord-278081-tk7vn1v1	87	14	typically	typically	RB
cord-278081-tk7vn1v1	87	15	surrounded	surround	VBN
cord-278081-tk7vn1v1	87	16	by	by	IN
cord-278081-tk7vn1v1	87	17	a	a	DT
cord-278081-tk7vn1v1	87	18	shell	shell	NN
cord-278081-tk7vn1v1	87	19	of	of	IN
cord-278081-tk7vn1v1	87	20	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	87	21	established	establish	VBN
cord-278081-tk7vn1v1	87	22	in	in	IN
cord-278081-tk7vn1v1	87	23	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	87	24	containing	contain	VBG
cord-278081-tk7vn1v1	87	25	nucleolar	nucleolar	NN
cord-278081-tk7vn1v1	87	26	-	-	HYPH
cord-278081-tk7vn1v1	87	27	associated	associate	VBN
cord-278081-tk7vn1v1	87	28	chromatin	chromatin	NN
cord-278081-tk7vn1v1	87	29	domains	domain	NNS
cord-278081-tk7vn1v1	87	30	(	(	-LRB-
cord-278081-tk7vn1v1	87	31	NADs	NADs	NNPS
cord-278081-tk7vn1v1	87	32	)	)	-RRB-
cord-278081-tk7vn1v1	87	33	(	(	-LRB-
cord-278081-tk7vn1v1	87	34	52	52	CD
cord-278081-tk7vn1v1	87	35	)	)	-RRB-
cord-278081-tk7vn1v1	87	36	.	.	.
cord-278081-tk7vn1v1	88	1	This	this	DT
cord-278081-tk7vn1v1	88	2	then	then	RB
cord-278081-tk7vn1v1	88	3	serves	serve	VBZ
cord-278081-tk7vn1v1	88	4	to	to	TO
cord-278081-tk7vn1v1	88	5	define	define	VB
cord-278081-tk7vn1v1	88	6	the	the	DT
cord-278081-tk7vn1v1	88	7	boundaries	boundary	NNS
cord-278081-tk7vn1v1	88	8	of	of	IN
cord-278081-tk7vn1v1	88	9	the	the	DT
cord-278081-tk7vn1v1	88	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	88	11	.	.	.
cord-278081-tk7vn1v1	89	1	The	the	DT
cord-278081-tk7vn1v1	89	2	NADs	nad	NNS
cord-278081-tk7vn1v1	89	3	contain	contain	VBP
cord-278081-tk7vn1v1	89	4	satellite	satellite	NN
cord-278081-tk7vn1v1	89	5	DNA	dna	NN
cord-278081-tk7vn1v1	89	6	,	,	,
cord-278081-tk7vn1v1	89	7	mostly	mostly	RB
cord-278081-tk7vn1v1	89	8	from	from	IN
cord-278081-tk7vn1v1	89	9	centromeric	centromeric	JJ
cord-278081-tk7vn1v1	89	10	and	and	CC
cord-278081-tk7vn1v1	89	11	pericentromeric	pericentromeric	JJ
cord-278081-tk7vn1v1	89	12	regions	region	NNS
cord-278081-tk7vn1v1	89	13	of	of	IN
cord-278081-tk7vn1v1	89	14	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	89	15	.	.	.
cord-278081-tk7vn1v1	90	1	The	the	DT
cord-278081-tk7vn1v1	90	2	NADs	nad	NNS
cord-278081-tk7vn1v1	90	3	also	also	RB
cord-278081-tk7vn1v1	90	4	contain	contain	VBP
cord-278081-tk7vn1v1	90	5	gene	gene	NN
cord-278081-tk7vn1v1	90	6	poor	poor	JJ
cord-278081-tk7vn1v1	90	7	and	and	CC
cord-278081-tk7vn1v1	90	8	silent	silent	JJ
cord-278081-tk7vn1v1	90	9	chromatin	chromatin	NN
cord-278081-tk7vn1v1	90	10	.	.	.
cord-278081-tk7vn1v1	91	1	In	in	IN
cord-278081-tk7vn1v1	91	2	addition	addition	NN
cord-278081-tk7vn1v1	91	3	,	,	,
cord-278081-tk7vn1v1	91	4	the	the	DT
cord-278081-tk7vn1v1	91	5	inactive	inactive	JJ
cord-278081-tk7vn1v1	91	6	X	x	NN
cord-278081-tk7vn1v1	91	7	chromosome	chromosome	NN
cord-278081-tk7vn1v1	91	8	(	(	-LRB-
cord-278081-tk7vn1v1	91	9	a.k.a	a.k.a	JJ
cord-278081-tk7vn1v1	91	10	.	.	.
cord-278081-tk7vn1v1	91	11	the	the	DT
cord-278081-tk7vn1v1	91	12	Barr	Barr	NNP
cord-278081-tk7vn1v1	91	13	body	body	NN
cord-278081-tk7vn1v1	91	14	)	)	-RRB-
cord-278081-tk7vn1v1	91	15	,	,	,
cord-278081-tk7vn1v1	91	16	a	a	DT
cord-278081-tk7vn1v1	91	17	heterochromatic	heterochromatic	JJ
cord-278081-tk7vn1v1	91	18	body	body	NN
cord-278081-tk7vn1v1	91	19	found	find	VBN
cord-278081-tk7vn1v1	91	20	in	in	IN
cord-278081-tk7vn1v1	91	21	most	most	JJS
cord-278081-tk7vn1v1	91	22	human	human	JJ
cord-278081-tk7vn1v1	91	23	female	female	JJ
cord-278081-tk7vn1v1	91	24	cells	cell	NNS
cord-278081-tk7vn1v1	91	25	,	,	,
cord-278081-tk7vn1v1	91	26	is	be	VBZ
cord-278081-tk7vn1v1	91	27	found	find	VBN
cord-278081-tk7vn1v1	91	28	in	in	IN
cord-278081-tk7vn1v1	91	29	close	close	JJ
cord-278081-tk7vn1v1	91	30	proximity	proximity	NN
cord-278081-tk7vn1v1	91	31	to	to	IN
cord-278081-tk7vn1v1	91	32	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	91	33	in	in	IN
cord-278081-tk7vn1v1	91	34	one	one	CD
cord-278081-tk7vn1v1	91	35	-	-	HYPH
cord-278081-tk7vn1v1	91	36	third	third	NN
cord-278081-tk7vn1v1	91	37	of	of	IN
cord-278081-tk7vn1v1	91	38	cells	cell	NNS
cord-278081-tk7vn1v1	91	39	throughout	throughout	IN
cord-278081-tk7vn1v1	91	40	the	the	DT
cord-278081-tk7vn1v1	91	41	cell	cell	NN
cord-278081-tk7vn1v1	91	42	cycle	cycle	NN
cord-278081-tk7vn1v1	91	43	and	and	CC
cord-278081-tk7vn1v1	91	44	90	90	CD
cord-278081-tk7vn1v1	91	45	%	%	NN
cord-278081-tk7vn1v1	91	46	of	of	IN
cord-278081-tk7vn1v1	91	47	cells	cell	NNS
cord-278081-tk7vn1v1	91	48	in	in	IN
cord-278081-tk7vn1v1	91	49	S	s	NN
cord-278081-tk7vn1v1	91	50	phase	phase	NN
cord-278081-tk7vn1v1	91	51	suggesting	suggest	VBG
cord-278081-tk7vn1v1	91	52	a	a	DT
cord-278081-tk7vn1v1	91	53	putative	putative	JJ
cord-278081-tk7vn1v1	91	54	role	role	NN
cord-278081-tk7vn1v1	91	55	for	for	IN
cord-278081-tk7vn1v1	91	56	the	the	DT
cord-278081-tk7vn1v1	91	57	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	91	58	in	in	IN
cord-278081-tk7vn1v1	91	59	maintaining	maintain	VBG
cord-278081-tk7vn1v1	91	60	X	x	NN
cord-278081-tk7vn1v1	91	61	chromosome	chromosome	NN
cord-278081-tk7vn1v1	91	62	inactivation	inactivation	NN
cord-278081-tk7vn1v1	91	63	(	(	-LRB-
cord-278081-tk7vn1v1	91	64	57	57	CD
cord-278081-tk7vn1v1	91	65	)	)	-RRB-
cord-278081-tk7vn1v1	91	66	.	.	.
cord-278081-tk7vn1v1	92	1	The	the	DT
cord-278081-tk7vn1v1	92	2	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	92	3	-	-	HYPH
cord-278081-tk7vn1v1	92	4	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	92	5	associations	association	NNS
cord-278081-tk7vn1v1	92	6	are	be	VBP
cord-278081-tk7vn1v1	92	7	facilitated	facilitate	VBN
cord-278081-tk7vn1v1	92	8	,	,	,
cord-278081-tk7vn1v1	92	9	in	in	IN
cord-278081-tk7vn1v1	92	10	general	general	JJ
cord-278081-tk7vn1v1	92	11	,	,	,
cord-278081-tk7vn1v1	92	12	by	by	IN
cord-278081-tk7vn1v1	92	13	insulator	insulator	NN
cord-278081-tk7vn1v1	92	14	proteins	protein	NNS
cord-278081-tk7vn1v1	92	15	,	,	,
cord-278081-tk7vn1v1	92	16	CTCF	CTCF	NNP
cord-278081-tk7vn1v1	92	17	(	(	-LRB-
cord-278081-tk7vn1v1	92	18	CCCTC	ccctc	NN
cord-278081-tk7vn1v1	92	19	-	-	HYPH
cord-278081-tk7vn1v1	92	20	binding	bind	VBG
cord-278081-tk7vn1v1	92	21	factor	factor	NN
cord-278081-tk7vn1v1	92	22	)	)	-RRB-
cord-278081-tk7vn1v1	92	23	and	and	CC
cord-278081-tk7vn1v1	92	24	nucleophosmin	nucleophosmin	NNS
cord-278081-tk7vn1v1	92	25	and	and	CC
cord-278081-tk7vn1v1	92	26	additionally	additionally	RB
cord-278081-tk7vn1v1	92	27	,	,	,
cord-278081-tk7vn1v1	92	28	in	in	IN
cord-278081-tk7vn1v1	92	29	the	the	DT
cord-278081-tk7vn1v1	92	30	case	case	NN
cord-278081-tk7vn1v1	92	31	of	of	IN
cord-278081-tk7vn1v1	92	32	the	the	DT
cord-278081-tk7vn1v1	92	33	inactive	inactive	JJ
cord-278081-tk7vn1v1	92	34	X	x	NN
cord-278081-tk7vn1v1	92	35	chromosome	chromosome	NN
cord-278081-tk7vn1v1	92	36	,	,	,
cord-278081-tk7vn1v1	92	37	by	by	IN
cord-278081-tk7vn1v1	92	38	X	x	NN
cord-278081-tk7vn1v1	92	39	inactivation	inactivation	NN
cord-278081-tk7vn1v1	92	40	specific	specific	JJ
cord-278081-tk7vn1v1	92	41	transcript	transcript	NN
cord-278081-tk7vn1v1	92	42	RNA	RNA	NNP
cord-278081-tk7vn1v1	92	43	.	.	.
cord-278081-tk7vn1v1	93	1	EBV	EBV	NNP
cord-278081-tk7vn1v1	93	2	latency	latency	NN
cord-278081-tk7vn1v1	93	3	can	can	MD
cord-278081-tk7vn1v1	93	4	be	be	VB
cord-278081-tk7vn1v1	93	5	controlled	control	VBN
cord-278081-tk7vn1v1	93	6	by	by	IN
cord-278081-tk7vn1v1	93	7	CTCF	CTCF	NNS
cord-278081-tk7vn1v1	93	8	bound	bind	VBN
cord-278081-tk7vn1v1	93	9	in	in	IN
cord-278081-tk7vn1v1	93	10	the	the	DT
cord-278081-tk7vn1v1	93	11	promoter	promoter	NN
cord-278081-tk7vn1v1	93	12	region	region	NN
cord-278081-tk7vn1v1	93	13	of	of	IN
cord-278081-tk7vn1v1	93	14	the	the	DT
cord-278081-tk7vn1v1	93	15	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	93	16	-	-	HYPH
cord-278081-tk7vn1v1	93	17	Barr	Barr	NNP
cord-278081-tk7vn1v1	93	18	virus	virus	NN
cord-278081-tk7vn1v1	93	19	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	93	20	antigen	antigen	NN
cord-278081-tk7vn1v1	93	21	2	2	CD
cord-278081-tk7vn1v1	93	22	(	(	-LRB-
cord-278081-tk7vn1v1	93	23	EBNA-2	EBNA-2	NNP
cord-278081-tk7vn1v1	93	24	)	)	-RRB-
cord-278081-tk7vn1v1	93	25	gene	gene	NN
cord-278081-tk7vn1v1	93	26	(	(	-LRB-
cord-278081-tk7vn1v1	93	27	58	58	CD
cord-278081-tk7vn1v1	93	28	)	)	-RRB-
cord-278081-tk7vn1v1	93	29	.	.	.
cord-278081-tk7vn1v1	94	1	Disruption	disruption	NN
cord-278081-tk7vn1v1	94	2	of	of	IN
cord-278081-tk7vn1v1	94	3	chromatin	chromatin	NN
cord-278081-tk7vn1v1	94	4	-	-	HYPH
cord-278081-tk7vn1v1	94	5	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	94	6	interactions	interaction	NNS
cord-278081-tk7vn1v1	94	7	could	could	MD
cord-278081-tk7vn1v1	94	8	lead	lead	VB
cord-278081-tk7vn1v1	94	9	to	to	IN
cord-278081-tk7vn1v1	94	10	changes	change	NNS
cord-278081-tk7vn1v1	94	11	in	in	IN
cord-278081-tk7vn1v1	94	12	EBV	EBV	NNP
cord-278081-tk7vn1v1	94	13	latency	latency	NN
cord-278081-tk7vn1v1	94	14	when	when	WRB
cord-278081-tk7vn1v1	94	15	CTCF	CTCF	NNP
cord-278081-tk7vn1v1	94	16	interactions	interaction	NNS
cord-278081-tk7vn1v1	94	17	with	with	IN
cord-278081-tk7vn1v1	94	18	inserted	insert	VBN
cord-278081-tk7vn1v1	94	19	EBV	EBV	NNP
cord-278081-tk7vn1v1	94	20	genes	gene	NNS
cord-278081-tk7vn1v1	94	21	are	be	VBP
cord-278081-tk7vn1v1	94	22	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	94	23	.	.	.
cord-278081-tk7vn1v1	95	1	In	in	IN
cord-278081-tk7vn1v1	95	2	addition	addition	NN
cord-278081-tk7vn1v1	95	3	,	,	,
cord-278081-tk7vn1v1	95	4	another	another	DT
cord-278081-tk7vn1v1	95	5	very	very	RB
cord-278081-tk7vn1v1	95	6	important	important	JJ
cord-278081-tk7vn1v1	95	7	point	point	NN
cord-278081-tk7vn1v1	95	8	to	to	TO
cord-278081-tk7vn1v1	95	9	keep	keep	VB
cord-278081-tk7vn1v1	95	10	in	in	IN
cord-278081-tk7vn1v1	95	11	mind	mind	NN
cord-278081-tk7vn1v1	95	12	is	be	VBZ
cord-278081-tk7vn1v1	95	13	that	that	IN
cord-278081-tk7vn1v1	95	14	nucleolin	nucleolin	NN
cord-278081-tk7vn1v1	95	15	bound	bind	VBN
cord-278081-tk7vn1v1	95	16	to	to	IN
cord-278081-tk7vn1v1	95	17	RNA	RNA	NNP
cord-278081-tk7vn1v1	95	18	polymerase	polymerase	NN
cord-278081-tk7vn1v1	95	19	II	II	NNP
cord-278081-tk7vn1v1	96	1	(	(	-LRB-
cord-278081-tk7vn1v1	96	2	RNA	RNA	NNP
cord-278081-tk7vn1v1	96	3	pol	pol	NN
cord-278081-tk7vn1v1	96	4	II	II	NNP
cord-278081-tk7vn1v1	96	5	)	)	-RRB-
cord-278081-tk7vn1v1	96	6	transcripts	transcript	NNS
cord-278081-tk7vn1v1	96	7	that	that	WDT
cord-278081-tk7vn1v1	96	8	contain	contain	VBP
cord-278081-tk7vn1v1	96	9	intronic	intronic	JJ
cord-278081-tk7vn1v1	96	10	Alu	Alu	NNP
cord-278081-tk7vn1v1	96	11	elements	element	NNS
cord-278081-tk7vn1v1	96	12	appear	appear	VBP
cord-278081-tk7vn1v1	96	13	to	to	TO
cord-278081-tk7vn1v1	96	14	have	have	VB
cord-278081-tk7vn1v1	96	15	a	a	DT
cord-278081-tk7vn1v1	96	16	critical	critical	JJ
cord-278081-tk7vn1v1	96	17	role	role	NN
cord-278081-tk7vn1v1	96	18	in	in	IN
cord-278081-tk7vn1v1	96	19	maintaining	maintain	VBG
cord-278081-tk7vn1v1	96	20	the	the	DT
cord-278081-tk7vn1v1	96	21	integrity	integrity	NN
cord-278081-tk7vn1v1	96	22	of	of	IN
cord-278081-tk7vn1v1	96	23	the	the	DT
cord-278081-tk7vn1v1	96	24	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	96	25	(	(	-LRB-
cord-278081-tk7vn1v1	96	26	59	59	CD
cord-278081-tk7vn1v1	96	27	)	)	-RRB-
cord-278081-tk7vn1v1	96	28	.	.	.
cord-278081-tk7vn1v1	97	1	When	when	WRB
cord-278081-tk7vn1v1	97	2	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	97	3	-	-	HYPH
cord-278081-tk7vn1v1	97	4	Herger	Herger	NNP
cord-278081-tk7vn1v1	97	5	and	and	CC
cord-278081-tk7vn1v1	97	6	colleagues	colleague	NNS
cord-278081-tk7vn1v1	97	7	added	add	VBD
cord-278081-tk7vn1v1	97	8	RNA	RNA	NNP
cord-278081-tk7vn1v1	97	9	pol	pol	NN
cord-278081-tk7vn1v1	97	10	III	III	NNP
cord-278081-tk7vn1v1	97	11	transcribed	transcribe	VBN
cord-278081-tk7vn1v1	97	12	Alu	Alu	NNP
cord-278081-tk7vn1v1	97	13	element	element	NN
cord-278081-tk7vn1v1	97	14	sequences	sequence	NNS
cord-278081-tk7vn1v1	97	15	,	,	,
cord-278081-tk7vn1v1	97	16	even	even	RB
cord-278081-tk7vn1v1	97	17	as	as	RB
cord-278081-tk7vn1v1	97	18	short	short	JJ
cord-278081-tk7vn1v1	97	19	as	as	IN
cord-278081-tk7vn1v1	97	20	20	20	CD
cord-278081-tk7vn1v1	97	21	nucleotides	nucleotide	NNS
cord-278081-tk7vn1v1	97	22	,	,	,
cord-278081-tk7vn1v1	97	23	there	there	EX
cord-278081-tk7vn1v1	97	24	was	be	VBD
cord-278081-tk7vn1v1	97	25	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	97	26	of	of	IN
cord-278081-tk7vn1v1	97	27	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	97	28	into	into	IN
cord-278081-tk7vn1v1	97	29	small	small	JJ
cord-278081-tk7vn1v1	97	30	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	97	31	-	-	HYPH
cord-278081-tk7vn1v1	97	32	like	like	JJ
cord-278081-tk7vn1v1	97	33	units	unit	NNS
cord-278081-tk7vn1v1	97	34	that	that	WDT
cord-278081-tk7vn1v1	97	35	were	be	VBD
cord-278081-tk7vn1v1	97	36	very	very	RB
cord-278081-tk7vn1v1	97	37	inefficient	inefficient	JJ
cord-278081-tk7vn1v1	97	38	in	in	IN
cord-278081-tk7vn1v1	97	39	carrying	carry	VBG
cord-278081-tk7vn1v1	97	40	out	out	RP
cord-278081-tk7vn1v1	97	41	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	97	42	functions	function	NNS
cord-278081-tk7vn1v1	97	43	of	of	IN
cord-278081-tk7vn1v1	97	44	RNA	RNA	NNP
cord-278081-tk7vn1v1	97	45	and	and	CC
cord-278081-tk7vn1v1	97	46	RNP	RNP	NNP
cord-278081-tk7vn1v1	97	47	processing	processing	NN
cord-278081-tk7vn1v1	97	48	and	and	CC
cord-278081-tk7vn1v1	97	49	assembly	assembly	NN
cord-278081-tk7vn1v1	97	50	(	(	-LRB-
cord-278081-tk7vn1v1	97	51	Figure	figure	NN
cord-278081-tk7vn1v1	97	52	1	1	CD
cord-278081-tk7vn1v1	97	53	)	)	-RRB-
cord-278081-tk7vn1v1	97	54	.	.	.
cord-278081-tk7vn1v1	98	1	The	the	DT
cord-278081-tk7vn1v1	98	2	authors	author	NNS
cord-278081-tk7vn1v1	98	3	proposed	propose	VBD
cord-278081-tk7vn1v1	98	4	that	that	IN
cord-278081-tk7vn1v1	98	5	the	the	DT
cord-278081-tk7vn1v1	98	6	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	98	7	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	98	8	was	be	VBD
cord-278081-tk7vn1v1	98	9	attributable	attributable	JJ
cord-278081-tk7vn1v1	98	10	to	to	IN
cord-278081-tk7vn1v1	98	11	Dicer	dicer	NN
cord-278081-tk7vn1v1	98	12	-	-	HYPH
cord-278081-tk7vn1v1	98	13	facilitated	facilitate	VBN
cord-278081-tk7vn1v1	98	14	degradation	degradation	NN
cord-278081-tk7vn1v1	98	15	of	of	IN
cord-278081-tk7vn1v1	98	16	hybridized	hybridize	VBN
cord-278081-tk7vn1v1	98	17	RNA	RNA	NNP
cord-278081-tk7vn1v1	98	18	pol	pol	NN
cord-278081-tk7vn1v1	98	19	III	III	NNP
cord-278081-tk7vn1v1	98	20	Alu	Alu	NNP
cord-278081-tk7vn1v1	98	21	sequences	sequence	NNS
cord-278081-tk7vn1v1	98	22	with	with	IN
cord-278081-tk7vn1v1	98	23	RNA	RNA	NNP
cord-278081-tk7vn1v1	98	24	pol	pol	NN
cord-278081-tk7vn1v1	98	25	II	II	NNP
cord-278081-tk7vn1v1	98	26	intronic	intronic	NNP
cord-278081-tk7vn1v1	98	27	Alu	Alu	NNP
cord-278081-tk7vn1v1	98	28	sequences	sequence	NNS
cord-278081-tk7vn1v1	98	29	.	.	.
cord-278081-tk7vn1v1	99	1	The	the	DT
cord-278081-tk7vn1v1	99	2	work	work	NN
cord-278081-tk7vn1v1	99	3	of	of	IN
cord-278081-tk7vn1v1	99	4	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	99	5	-	-	HYPH
cord-278081-tk7vn1v1	99	6	Herger	Herger	NNP
cord-278081-tk7vn1v1	99	7	and	and	CC
cord-278081-tk7vn1v1	99	8	colleagues	colleague	NNS
cord-278081-tk7vn1v1	99	9	demonstrates	demonstrate	VBZ
cord-278081-tk7vn1v1	99	10	a	a	DT
cord-278081-tk7vn1v1	99	11	close	close	JJ
cord-278081-tk7vn1v1	99	12	connection	connection	NN
cord-278081-tk7vn1v1	99	13	between	between	IN
cord-278081-tk7vn1v1	99	14	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	99	15	integrity	integrity	NN
cord-278081-tk7vn1v1	99	16	and	and	CC
cord-278081-tk7vn1v1	99	17	the	the	DT
cord-278081-tk7vn1v1	99	18	complexes	complex	NNS
cord-278081-tk7vn1v1	99	19	of	of	IN
cord-278081-tk7vn1v1	99	20	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	99	21	with	with	IN
cord-278081-tk7vn1v1	99	22	RNA	RNA	NNP
cord-278081-tk7vn1v1	99	23	pol	pol	NN
cord-278081-tk7vn1v1	99	24	II	II	NNP
cord-278081-tk7vn1v1	99	25	transcripts	transcript	NNS
cord-278081-tk7vn1v1	99	26	containing	contain	VBG
cord-278081-tk7vn1v1	99	27	intronic	intronic	NNP
cord-278081-tk7vn1v1	99	28	Alu	Alu	NNP
cord-278081-tk7vn1v1	99	29	sequences	sequence	NNS
cord-278081-tk7vn1v1	99	30	.	.	.
cord-278081-tk7vn1v1	100	1	Another	another	DT
cord-278081-tk7vn1v1	100	2	possibility	possibility	NN
cord-278081-tk7vn1v1	100	3	for	for	IN
cord-278081-tk7vn1v1	100	4	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	100	5	disruption	disruption	NN
cord-278081-tk7vn1v1	100	6	by	by	IN
cord-278081-tk7vn1v1	100	7	RNA	RNA	NNP
cord-278081-tk7vn1v1	100	8	pol	pol	NN
cord-278081-tk7vn1v1	100	9	III	III	NNP
cord-278081-tk7vn1v1	100	10	Alu	Alu	NNP
cord-278081-tk7vn1v1	100	11	transcripts	transcript	NNS
cord-278081-tk7vn1v1	100	12	that	that	WDT
cord-278081-tk7vn1v1	100	13	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	100	14	-	-	HYPH
cord-278081-tk7vn1v1	100	15	Herger	Herger	NNP
cord-278081-tk7vn1v1	100	16	and	and	CC
cord-278081-tk7vn1v1	100	17	colleagues	colleague	NNS
cord-278081-tk7vn1v1	100	18	did	do	VBD
cord-278081-tk7vn1v1	100	19	not	not	RB
cord-278081-tk7vn1v1	100	20	mention	mention	VB
cord-278081-tk7vn1v1	100	21	is	be	VBZ
cord-278081-tk7vn1v1	100	22	possible	possible	JJ
cord-278081-tk7vn1v1	100	23	competition	competition	NN
cord-278081-tk7vn1v1	100	24	for	for	IN
cord-278081-tk7vn1v1	100	25	nucleolin	nucleolin	NN
cord-278081-tk7vn1v1	100	26	between	between	IN
cord-278081-tk7vn1v1	100	27	the	the	DT
cord-278081-tk7vn1v1	100	28	RNA	RNA	NNP
cord-278081-tk7vn1v1	100	29	pol	pol	NN
cord-278081-tk7vn1v1	100	30	II	II	NNP
cord-278081-tk7vn1v1	100	31	intronic	intronic	NNP
cord-278081-tk7vn1v1	100	32	Alu	Alu	NNP
cord-278081-tk7vn1v1	100	33	sequences	sequence	NNS
cord-278081-tk7vn1v1	100	34	and	and	CC
cord-278081-tk7vn1v1	100	35	a	a	DT
cord-278081-tk7vn1v1	100	36	sudden	sudden	JJ
cord-278081-tk7vn1v1	100	37	abundance	abundance	NN
cord-278081-tk7vn1v1	100	38	of	of	IN
cord-278081-tk7vn1v1	100	39	RNA	rna	NN
cord-278081-tk7vn1v1	100	40	pol	pol	NN
cord-278081-tk7vn1v1	100	41	III	III	NNP
cord-278081-tk7vn1v1	100	42	Alu	Alu	NNP
cord-278081-tk7vn1v1	100	43	transcripts	transcript	NNS
cord-278081-tk7vn1v1	100	44	.	.	.
cord-278081-tk7vn1v1	101	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	101	2	believe	believe	VBP
cord-278081-tk7vn1v1	101	3	this	this	DT
cord-278081-tk7vn1v1	101	4	could	could	MD
cord-278081-tk7vn1v1	101	5	have	have	VB
cord-278081-tk7vn1v1	101	6	a	a	DT
cord-278081-tk7vn1v1	101	7	major	major	JJ
cord-278081-tk7vn1v1	101	8	role	role	NN
cord-278081-tk7vn1v1	101	9	in	in	IN
cord-278081-tk7vn1v1	101	10	generation	generation	NN
cord-278081-tk7vn1v1	101	11	of	of	IN
cord-278081-tk7vn1v1	101	12	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	101	13	as	as	IN
cord-278081-tk7vn1v1	101	14	we	-PRON-	PRP
cord-278081-tk7vn1v1	101	15	will	will	MD
cord-278081-tk7vn1v1	101	16	explain	explain	VB
cord-278081-tk7vn1v1	101	17	below	below	RB
cord-278081-tk7vn1v1	101	18	.	.	.
cord-278081-tk7vn1v1	102	1	Normally	normally	RB
cord-278081-tk7vn1v1	102	2	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	102	3	contain	contain	VBP
cord-278081-tk7vn1v1	102	4	three	three	CD
cord-278081-tk7vn1v1	102	5	discernable	discernable	JJ
cord-278081-tk7vn1v1	102	6	sub	sub	NN
cord-278081-tk7vn1v1	102	7	-	-	NNS
cord-278081-tk7vn1v1	102	8	regions	region	NNS
cord-278081-tk7vn1v1	102	9	:	:	:
cord-278081-tk7vn1v1	102	10	the	the	DT
cord-278081-tk7vn1v1	102	11	fibrillary	fibrillary	NNP
cord-278081-tk7vn1v1	102	12	centers	centers	NNPS
cord-278081-tk7vn1v1	102	13	(	(	-LRB-
cord-278081-tk7vn1v1	102	14	FCs	FCs	NNP
cord-278081-tk7vn1v1	102	15	)	)	-RRB-
cord-278081-tk7vn1v1	102	16	,	,	,
cord-278081-tk7vn1v1	102	17	the	the	DT
cord-278081-tk7vn1v1	102	18	dense	dense	JJ
cord-278081-tk7vn1v1	102	19	fibrillary	fibrillary	JJ
cord-278081-tk7vn1v1	102	20	centers	center	NNS
cord-278081-tk7vn1v1	102	21	(	(	-LRB-
cord-278081-tk7vn1v1	102	22	DFCs	DFCs	NNP
cord-278081-tk7vn1v1	102	23	)	)	-RRB-
cord-278081-tk7vn1v1	102	24	,	,	,
cord-278081-tk7vn1v1	102	25	and	and	CC
cord-278081-tk7vn1v1	102	26	the	the	DT
cord-278081-tk7vn1v1	102	27	granular	granular	JJ
cord-278081-tk7vn1v1	102	28	components	component	NNS
cord-278081-tk7vn1v1	102	29	(	(	-LRB-
cord-278081-tk7vn1v1	102	30	GCs	GCs	NNP
cord-278081-tk7vn1v1	102	31	)	)	-RRB-
cord-278081-tk7vn1v1	102	32	.	.	.
cord-278081-tk7vn1v1	103	1	The	the	DT
cord-278081-tk7vn1v1	103	2	FCs	fc	NNS
cord-278081-tk7vn1v1	103	3	are	be	VBP
cord-278081-tk7vn1v1	103	4	the	the	DT
cord-278081-tk7vn1v1	103	5	sites	site	NNS
cord-278081-tk7vn1v1	103	6	of	of	IN
cord-278081-tk7vn1v1	103	7	rDNA	rDNA	NNP
cord-278081-tk7vn1v1	103	8	transcription	transcription	NN
cord-278081-tk7vn1v1	103	9	by	by	IN
cord-278081-tk7vn1v1	103	10	RNA	RNA	NNP
cord-278081-tk7vn1v1	103	11	polymerase	polymerase	NN
cord-278081-tk7vn1v1	103	12	I	I	NNP
cord-278081-tk7vn1v1	103	13	(	(	-LRB-
cord-278081-tk7vn1v1	103	14	RNA	rna	NN
cord-278081-tk7vn1v1	103	15	pol	pol	NN
cord-278081-tk7vn1v1	103	16	I	i	NN
cord-278081-tk7vn1v1	103	17	)	)	-RRB-
cord-278081-tk7vn1v1	103	18	to	to	TO
cord-278081-tk7vn1v1	103	19	generate	generate	VB
cord-278081-tk7vn1v1	103	20	the	the	DT
cord-278081-tk7vn1v1	103	21	initial	initial	JJ
cord-278081-tk7vn1v1	103	22	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	103	23	RNA	RNA	NNP
cord-278081-tk7vn1v1	103	24	transcript	transcript	NN
cord-278081-tk7vn1v1	103	25	,	,	,
cord-278081-tk7vn1v1	103	26	the	the	DT
cord-278081-tk7vn1v1	103	27	pre	pre	NN
cord-278081-tk7vn1v1	103	28	-	-	NN
cord-278081-tk7vn1v1	103	29	rRNA	rrna	JJ
cord-278081-tk7vn1v1	103	30	.	.	.
cord-278081-tk7vn1v1	104	1	Only	only	RB
cord-278081-tk7vn1v1	104	2	50	50	CD
cord-278081-tk7vn1v1	104	3	%	%	NN
cord-278081-tk7vn1v1	104	4	of	of	IN
cord-278081-tk7vn1v1	104	5	the	the	DT
cord-278081-tk7vn1v1	104	6	~400	~400	NNP
cord-278081-tk7vn1v1	104	7	rDNA	rDNA	NNP
cord-278081-tk7vn1v1	104	8	repeats	repeat	VBZ
cord-278081-tk7vn1v1	104	9	in	in	IN
cord-278081-tk7vn1v1	104	10	the	the	DT
cord-278081-tk7vn1v1	104	11	human	human	JJ
cord-278081-tk7vn1v1	104	12	diploid	diploid	JJ
cord-278081-tk7vn1v1	104	13	genome	genome	NN
cord-278081-tk7vn1v1	104	14	are	be	VBP
cord-278081-tk7vn1v1	104	15	transcriptionally	transcriptionally	RB
cord-278081-tk7vn1v1	104	16	active	active	JJ
cord-278081-tk7vn1v1	104	17	(	(	-LRB-
cord-278081-tk7vn1v1	104	18	60	60	CD
cord-278081-tk7vn1v1	104	19	)	)	-RRB-
cord-278081-tk7vn1v1	104	20	.	.	.
cord-278081-tk7vn1v1	105	1	Processing	processing	NN
cord-278081-tk7vn1v1	105	2	of	of	IN
cord-278081-tk7vn1v1	105	3	the	the	DT
cord-278081-tk7vn1v1	105	4	pre	pre	NN
cord-278081-tk7vn1v1	105	5	-	-	JJ
cord-278081-tk7vn1v1	105	6	rRNA	rrna	JJ
cord-278081-tk7vn1v1	105	7	occurs	occur	VBZ
cord-278081-tk7vn1v1	105	8	primarily	primarily	RB
cord-278081-tk7vn1v1	105	9	in	in	IN
cord-278081-tk7vn1v1	105	10	the	the	DT
cord-278081-tk7vn1v1	105	11	DFCs	dfc	NNS
cord-278081-tk7vn1v1	105	12	assisted	assist	VBN
cord-278081-tk7vn1v1	105	13	by	by	IN
cord-278081-tk7vn1v1	105	14	small	small	JJ
cord-278081-tk7vn1v1	105	15	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	105	16	RNAs	rna	NNS
cord-278081-tk7vn1v1	105	17	(	(	-LRB-
cord-278081-tk7vn1v1	105	18	snoRNAs	snoRNAs	NNP
cord-278081-tk7vn1v1	105	19	)	)	-RRB-
cord-278081-tk7vn1v1	105	20	.	.	.
cord-278081-tk7vn1v1	106	1	Assembly	assembly	NN
cord-278081-tk7vn1v1	106	2	of	of	IN
cord-278081-tk7vn1v1	106	3	the	the	DT
cord-278081-tk7vn1v1	106	4	final	final	JJ
cord-278081-tk7vn1v1	106	5	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	106	6	subunits	subunit	NNS
cord-278081-tk7vn1v1	106	7	occurs	occur	VBZ
cord-278081-tk7vn1v1	106	8	in	in	IN
cord-278081-tk7vn1v1	106	9	the	the	DT
cord-278081-tk7vn1v1	106	10	GC	GC	NNP
cord-278081-tk7vn1v1	106	11	,	,	,
cord-278081-tk7vn1v1	106	12	which	which	WDT
cord-278081-tk7vn1v1	106	13	has	have	VBZ
cord-278081-tk7vn1v1	106	14	a	a	DT
cord-278081-tk7vn1v1	106	15	high	high	JJ
cord-278081-tk7vn1v1	106	16	concentration	concentration	NN
cord-278081-tk7vn1v1	106	17	of	of	IN
cord-278081-tk7vn1v1	106	18	proteins	protein	NNS
cord-278081-tk7vn1v1	106	19	needed	need	VBN
cord-278081-tk7vn1v1	106	20	to	to	TO
cord-278081-tk7vn1v1	106	21	complete	complete	VB
cord-278081-tk7vn1v1	106	22	the	the	DT
cord-278081-tk7vn1v1	106	23	RNPs	rnp	NNS
cord-278081-tk7vn1v1	106	24	(	(	-LRB-
cord-278081-tk7vn1v1	106	25	61	61	CD
cord-278081-tk7vn1v1	106	26	)	)	-RRB-
cord-278081-tk7vn1v1	106	27	.	.	.
cord-278081-tk7vn1v1	107	1	Other	other	JJ
cord-278081-tk7vn1v1	107	2	RNAs	rna	NNS
cord-278081-tk7vn1v1	107	3	and	and	CC
cord-278081-tk7vn1v1	107	4	RNPs	rnp	NNS
cord-278081-tk7vn1v1	107	5	processed	process	VBN
cord-278081-tk7vn1v1	107	6	and	and	CC
cord-278081-tk7vn1v1	107	7	assembled	assemble	VBN
cord-278081-tk7vn1v1	107	8	in	in	IN
cord-278081-tk7vn1v1	107	9	the	the	DT
cord-278081-tk7vn1v1	107	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	107	11	include	include	VBP
cord-278081-tk7vn1v1	107	12	:	:	:
cord-278081-tk7vn1v1	107	13	the	the	DT
cord-278081-tk7vn1v1	107	14	signal	signal	NN
cord-278081-tk7vn1v1	107	15	recognition	recognition	NN
cord-278081-tk7vn1v1	107	16	particle	particle	NN
cord-278081-tk7vn1v1	107	17	(	(	-LRB-
cord-278081-tk7vn1v1	107	18	SRP	SRP	NNP
cord-278081-tk7vn1v1	107	19	)	)	-RRB-
cord-278081-tk7vn1v1	107	20	which	which	WDT
cord-278081-tk7vn1v1	107	21	controls	control	VBZ
cord-278081-tk7vn1v1	107	22	translation	translation	NN
cord-278081-tk7vn1v1	107	23	and	and	CC
cord-278081-tk7vn1v1	107	24	localization	localization	NN
cord-278081-tk7vn1v1	107	25	of	of	IN
cord-278081-tk7vn1v1	107	26	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	107	27	proteins	protein	NNS
cord-278081-tk7vn1v1	107	28	by	by	IN
cord-278081-tk7vn1v1	107	29	transporting	transport	VBG
cord-278081-tk7vn1v1	107	30	them	-PRON-	PRP
cord-278081-tk7vn1v1	107	31	to	to	IN
cord-278081-tk7vn1v1	107	32	the	the	DT
cord-278081-tk7vn1v1	107	33	endoplasmic	endoplasmic	NN
cord-278081-tk7vn1v1	107	34	reticulum	reticulum	NN
cord-278081-tk7vn1v1	107	35	(	(	-LRB-
cord-278081-tk7vn1v1	107	36	ER	ER	NNP
cord-278081-tk7vn1v1	107	37	)	)	-RRB-
cord-278081-tk7vn1v1	107	38	for	for	IN
cord-278081-tk7vn1v1	107	39	eventual	eventual	JJ
cord-278081-tk7vn1v1	107	40	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	107	41	release	release	NN
cord-278081-tk7vn1v1	107	42	;	;	:
cord-278081-tk7vn1v1	107	43	tRNAs	trna	NNS
cord-278081-tk7vn1v1	107	44	which	which	WDT
cord-278081-tk7vn1v1	107	45	require	require	VBP
cord-278081-tk7vn1v1	107	46	extensive	extensive	JJ
cord-278081-tk7vn1v1	107	47	folding	folding	NN
cord-278081-tk7vn1v1	107	48	;	;	:
cord-278081-tk7vn1v1	107	49	small	small	JJ
cord-278081-tk7vn1v1	107	50	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	107	51	ribonucleoprotein	ribonucleoprotein	NN
cord-278081-tk7vn1v1	107	52	complexes	complex	NNS
cord-278081-tk7vn1v1	107	53	involved	involve	VBN
cord-278081-tk7vn1v1	107	54	in	in	IN
cord-278081-tk7vn1v1	107	55	splicing	splicing	NN
cord-278081-tk7vn1v1	107	56	of	of	IN
cord-278081-tk7vn1v1	107	57	messenger	messenger	NN
cord-278081-tk7vn1v1	107	58	RNAs	rna	NNS
cord-278081-tk7vn1v1	107	59	(	(	-LRB-
cord-278081-tk7vn1v1	107	60	mRNAs	mrnas	CD
cord-278081-tk7vn1v1	107	61	)	)	-RRB-
cord-278081-tk7vn1v1	107	62	;	;	:
cord-278081-tk7vn1v1	107	63	and	and	CC
cord-278081-tk7vn1v1	107	64	centromere	centromere	NN
cord-278081-tk7vn1v1	107	65	components	component	NNS
cord-278081-tk7vn1v1	107	66	.	.	.
cord-278081-tk7vn1v1	108	1	Therefore	therefore	RB
cord-278081-tk7vn1v1	108	2	,	,	,
cord-278081-tk7vn1v1	108	3	the	the	DT
cord-278081-tk7vn1v1	108	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	108	5	is	be	VBZ
cord-278081-tk7vn1v1	108	6	involved	involve	VBN
cord-278081-tk7vn1v1	108	7	directly	directly	RB
cord-278081-tk7vn1v1	108	8	or	or	CC
cord-278081-tk7vn1v1	108	9	indirectly	indirectly	RB
cord-278081-tk7vn1v1	108	10	in	in	IN
cord-278081-tk7vn1v1	108	11	many	many	JJ
cord-278081-tk7vn1v1	108	12	cellular	cellular	JJ
cord-278081-tk7vn1v1	108	13	functions	function	NNS
cord-278081-tk7vn1v1	108	14	,	,	,
cord-278081-tk7vn1v1	108	15	such	such	JJ
cord-278081-tk7vn1v1	108	16	as	as	IN
cord-278081-tk7vn1v1	108	17	regulation	regulation	NN
cord-278081-tk7vn1v1	108	18	of	of	IN
cord-278081-tk7vn1v1	108	19	mitosis	mitosis	NN
cord-278081-tk7vn1v1	108	20	;	;	:
cord-278081-tk7vn1v1	108	21	cell	cell	NN
cord-278081-tk7vn1v1	108	22	-	-	HYPH
cord-278081-tk7vn1v1	108	23	cycle	cycle	NN
cord-278081-tk7vn1v1	108	24	progression	progression	NN
cord-278081-tk7vn1v1	108	25	;	;	:
cord-278081-tk7vn1v1	108	26	cell	cell	NN
cord-278081-tk7vn1v1	108	27	proliferation	proliferation	NN
cord-278081-tk7vn1v1	108	28	;	;	:
cord-278081-tk7vn1v1	108	29	mRNA	mrna	NN
cord-278081-tk7vn1v1	108	30	processing	processing	NN
cord-278081-tk7vn1v1	108	31	via	via	IN
cord-278081-tk7vn1v1	108	32	splicing	splicing	NN
cord-278081-tk7vn1v1	108	33	;	;	:
cord-278081-tk7vn1v1	108	34	translation	translation	NN
cord-278081-tk7vn1v1	108	35	;	;	:
cord-278081-tk7vn1v1	108	36	protein	protein	NN
cord-278081-tk7vn1v1	108	37	localization	localization	NN
cord-278081-tk7vn1v1	108	38	;	;	,
cord-278081-tk7vn1v1	108	39	and	and	CC
cord-278081-tk7vn1v1	108	40	various	various	JJ
cord-278081-tk7vn1v1	108	41	forms	form	NNS
cord-278081-tk7vn1v1	108	42	of	of	IN
cord-278081-tk7vn1v1	108	43	stress	stress	NN
cord-278081-tk7vn1v1	108	44	response	response	NN
cord-278081-tk7vn1v1	108	45	.	.	.
cord-278081-tk7vn1v1	109	1	The	the	DT
cord-278081-tk7vn1v1	109	2	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	109	3	proteome	proteome	NN
cord-278081-tk7vn1v1	109	4	contains	contain	VBZ
cord-278081-tk7vn1v1	109	5	over	over	IN
cord-278081-tk7vn1v1	109	6	4,500	4,500	CD
cord-278081-tk7vn1v1	109	7	proteins	protein	NNS
cord-278081-tk7vn1v1	109	8	according	accord	VBG
cord-278081-tk7vn1v1	109	9	to	to	IN
cord-278081-tk7vn1v1	109	10	the	the	DT
cord-278081-tk7vn1v1	109	11	nucleolar	nucleolar	NNP
cord-278081-tk7vn1v1	109	12	proteome	proteome	NN
cord-278081-tk7vn1v1	109	13	database	database	NN
cord-278081-tk7vn1v1	109	14	,	,	,
cord-278081-tk7vn1v1	109	15	NOPdb3.0	NOPdb3.0	NNP
cord-278081-tk7vn1v1	109	16	(	(	-LRB-
cord-278081-tk7vn1v1	109	17	62	62	CD
cord-278081-tk7vn1v1	109	18	)	)	-RRB-
cord-278081-tk7vn1v1	109	19	.	.	.
cord-278081-tk7vn1v1	110	1	About	about	RB
cord-278081-tk7vn1v1	110	2	30	30	CD
cord-278081-tk7vn1v1	110	3	%	%	NN
cord-278081-tk7vn1v1	110	4	of	of	IN
cord-278081-tk7vn1v1	110	5	these	these	DT
cord-278081-tk7vn1v1	110	6	proteins	protein	NNS
cord-278081-tk7vn1v1	110	7	are	be	VBP
cord-278081-tk7vn1v1	110	8	involved	involve	VBN
cord-278081-tk7vn1v1	110	9	in	in	IN
cord-278081-tk7vn1v1	110	10	ribosome	ribosome	NN
cord-278081-tk7vn1v1	110	11	biogenesis	biogenesis	NN
cord-278081-tk7vn1v1	110	12	.	.	.
cord-278081-tk7vn1v1	111	1	Since	since	IN
cord-278081-tk7vn1v1	111	2	the	the	DT
cord-278081-tk7vn1v1	111	3	demands	demand	NNS
cord-278081-tk7vn1v1	111	4	on	on	IN
cord-278081-tk7vn1v1	111	5	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	111	6	output	output	NN
cord-278081-tk7vn1v1	111	7	can	can	MD
cord-278081-tk7vn1v1	111	8	change	change	VB
cord-278081-tk7vn1v1	111	9	rapidly	rapidly	RB
cord-278081-tk7vn1v1	111	10	,	,	,
cord-278081-tk7vn1v1	111	11	the	the	DT
cord-278081-tk7vn1v1	111	12	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	111	13	proteome	proteome	NN
cord-278081-tk7vn1v1	111	14	is	be	VBZ
cord-278081-tk7vn1v1	111	15	very	very	RB
cord-278081-tk7vn1v1	111	16	dynamic	dynamic	JJ
cord-278081-tk7vn1v1	111	17	.	.	.
cord-278081-tk7vn1v1	112	1	In	in	IN
cord-278081-tk7vn1v1	112	2	addition	addition	NN
cord-278081-tk7vn1v1	112	3	,	,	,
cord-278081-tk7vn1v1	112	4	the	the	DT
cord-278081-tk7vn1v1	112	5	size	size	NN
cord-278081-tk7vn1v1	112	6	of	of	IN
cord-278081-tk7vn1v1	112	7	the	the	DT
cord-278081-tk7vn1v1	112	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	112	9	can	can	MD
cord-278081-tk7vn1v1	112	10	change	change	VB
cord-278081-tk7vn1v1	112	11	dramatically	dramatically	RB
cord-278081-tk7vn1v1	112	12	depending	depend	VBG
cord-278081-tk7vn1v1	112	13	on	on	IN
cord-278081-tk7vn1v1	112	14	the	the	DT
cord-278081-tk7vn1v1	112	15	needs	need	NNS
cord-278081-tk7vn1v1	112	16	.	.	.
cord-278081-tk7vn1v1	113	1	Increased	increase	VBN
cord-278081-tk7vn1v1	113	2	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	113	3	size	size	NN
cord-278081-tk7vn1v1	113	4	correlates	correlate	VBZ
cord-278081-tk7vn1v1	113	5	directly	directly	RB
cord-278081-tk7vn1v1	113	6	with	with	IN
cord-278081-tk7vn1v1	113	7	increases	increase	NNS
cord-278081-tk7vn1v1	113	8	in	in	IN
cord-278081-tk7vn1v1	113	9	polyamine	polyamine	NN
cord-278081-tk7vn1v1	113	10	synthesis	synthesis	NN
cord-278081-tk7vn1v1	113	11	(	(	-LRB-
cord-278081-tk7vn1v1	113	12	63	63	CD
cord-278081-tk7vn1v1	113	13	)	)	-RRB-
cord-278081-tk7vn1v1	113	14	.	.	.
cord-278081-tk7vn1v1	114	1	The	the	DT
cord-278081-tk7vn1v1	114	2	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	114	3	,	,	,
cord-278081-tk7vn1v1	114	4	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	114	5	and	and	CC
cord-278081-tk7vn1v1	114	6	spermine	spermine	NNP
cord-278081-tk7vn1v1	114	7	,	,	,
cord-278081-tk7vn1v1	114	8	are	be	VBP
cord-278081-tk7vn1v1	114	9	involved	involve	VBN
cord-278081-tk7vn1v1	114	10	in	in	IN
cord-278081-tk7vn1v1	114	11	many	many	JJ
cord-278081-tk7vn1v1	114	12	cellular	cellular	JJ
cord-278081-tk7vn1v1	114	13	functions	function	NNS
cord-278081-tk7vn1v1	114	14	but	but	CC
cord-278081-tk7vn1v1	114	15	their	-PRON-	PRP$
cord-278081-tk7vn1v1	114	16	highest	high	JJS
cord-278081-tk7vn1v1	114	17	concentrations	concentration	NNS
cord-278081-tk7vn1v1	114	18	are	be	VBP
cord-278081-tk7vn1v1	114	19	found	find	VBN
cord-278081-tk7vn1v1	114	20	in	in	IN
cord-278081-tk7vn1v1	114	21	the	the	DT
cord-278081-tk7vn1v1	114	22	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	114	23	where	where	WRB
cord-278081-tk7vn1v1	114	24	the	the	DT
cord-278081-tk7vn1v1	114	25	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	114	26	assist	assist	VBP
cord-278081-tk7vn1v1	114	27	in	in	IN
cord-278081-tk7vn1v1	114	28	folding	folding	NN
cord-278081-tk7vn1v1	114	29	of	of	IN
cord-278081-tk7vn1v1	114	30	RNA	RNA	NNP
cord-278081-tk7vn1v1	114	31	transcripts	transcript	NNS
cord-278081-tk7vn1v1	114	32	and	and	CC
cord-278081-tk7vn1v1	114	33	assembly	assembly	NN
cord-278081-tk7vn1v1	114	34	of	of	IN
cord-278081-tk7vn1v1	114	35	RNPs	rnp	NNS
cord-278081-tk7vn1v1	114	36	.	.	.
cord-278081-tk7vn1v1	115	1	The	the	DT
cord-278081-tk7vn1v1	115	2	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	115	3	have	have	VBP
cord-278081-tk7vn1v1	115	4	a	a	DT
cord-278081-tk7vn1v1	115	5	unique	unique	JJ
cord-278081-tk7vn1v1	115	6	combination	combination	NN
cord-278081-tk7vn1v1	115	7	of	of	IN
cord-278081-tk7vn1v1	115	8	length	length	NN
cord-278081-tk7vn1v1	116	1	(	(	-LRB-
cord-278081-tk7vn1v1	116	2	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	116	3	~11	~11	NNP
cord-278081-tk7vn1v1	116	4	Å	Å	NNP
cord-278081-tk7vn1v1	116	5	spermine	spermine	FW
cord-278081-tk7vn1v1	116	6	~14	~14	FW
cord-278081-tk7vn1v1	116	7	Å	å	NN
cord-278081-tk7vn1v1	116	8	)	)	-RRB-
cord-278081-tk7vn1v1	116	9	,	,	,
cord-278081-tk7vn1v1	116	10	flexibility	flexibility	NN
cord-278081-tk7vn1v1	116	11	(	(	-LRB-
cord-278081-tk7vn1v1	116	12	all	all	DT
cord-278081-tk7vn1v1	116	13	single	single	JJ
cord-278081-tk7vn1v1	116	14	bonds	bond	NNS
cord-278081-tk7vn1v1	116	15	)	)	-RRB-
cord-278081-tk7vn1v1	116	16	and	and	CC
cord-278081-tk7vn1v1	116	17	high	high	JJ
cord-278081-tk7vn1v1	116	18	cationic	cationic	JJ
cord-278081-tk7vn1v1	116	19	charge	charge	NN
cord-278081-tk7vn1v1	116	20	at	at	IN
cord-278081-tk7vn1v1	116	21	physiological	physiological	JJ
cord-278081-tk7vn1v1	116	22	pH	pH	NNP
cord-278081-tk7vn1v1	116	23	(	(	-LRB-
cord-278081-tk7vn1v1	116	24	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	116	25	+3	+3	NNP
cord-278081-tk7vn1v1	116	26	;	;	:
cord-278081-tk7vn1v1	116	27	spermine	spermine	NNP
cord-278081-tk7vn1v1	116	28	+4	+4	NNP
cord-278081-tk7vn1v1	116	29	)	)	-RRB-
cord-278081-tk7vn1v1	116	30	which	which	WDT
cord-278081-tk7vn1v1	116	31	makes	make	VBZ
cord-278081-tk7vn1v1	116	32	them	-PRON-	PRP
cord-278081-tk7vn1v1	116	33	ideal	ideal	JJ
cord-278081-tk7vn1v1	116	34	counter	counter	NN
cord-278081-tk7vn1v1	116	35	ions	ion	NNS
cord-278081-tk7vn1v1	116	36	to	to	TO
cord-278081-tk7vn1v1	116	37	assist	assist	VB
cord-278081-tk7vn1v1	116	38	in	in	IN
cord-278081-tk7vn1v1	116	39	folding	fold	VBG
cord-278081-tk7vn1v1	116	40	the	the	DT
cord-278081-tk7vn1v1	116	41	negatively	negatively	RB
cord-278081-tk7vn1v1	116	42	charged	charge	VBN
cord-278081-tk7vn1v1	116	43	RNA	RNA	NNP
cord-278081-tk7vn1v1	116	44	transcripts	transcript	NNS
cord-278081-tk7vn1v1	116	45	in	in	IN
cord-278081-tk7vn1v1	116	46	the	the	DT
cord-278081-tk7vn1v1	116	47	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	116	48	.	.	.
cord-278081-tk7vn1v1	117	1	Nucleoli	Nucleoli	NNP
cord-278081-tk7vn1v1	117	2	are	be	VBP
cord-278081-tk7vn1v1	117	3	very	very	RB
cord-278081-tk7vn1v1	117	4	dynamic	dynamic	JJ
cord-278081-tk7vn1v1	117	5	structures	structure	NNS
cord-278081-tk7vn1v1	117	6	in	in	IN
cord-278081-tk7vn1v1	117	7	the	the	DT
cord-278081-tk7vn1v1	117	8	cell	cell	NN
cord-278081-tk7vn1v1	117	9	and	and	CC
cord-278081-tk7vn1v1	117	10	cell	cell	NN
cord-278081-tk7vn1v1	117	11	cycle	cycle	NN
cord-278081-tk7vn1v1	117	12	.	.	.
cord-278081-tk7vn1v1	118	1	There	there	EX
cord-278081-tk7vn1v1	118	2	can	can	MD
cord-278081-tk7vn1v1	118	3	be	be	VB
cord-278081-tk7vn1v1	118	4	more	more	JJR
cord-278081-tk7vn1v1	118	5	than	than	IN
cord-278081-tk7vn1v1	118	6	one	one	CD
cord-278081-tk7vn1v1	118	7	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	118	8	in	in	IN
cord-278081-tk7vn1v1	118	9	the	the	DT
cord-278081-tk7vn1v1	118	10	nucleus	nucleus	NN
cord-278081-tk7vn1v1	118	11	and	and	CC
cord-278081-tk7vn1v1	118	12	,	,	,
cord-278081-tk7vn1v1	118	13	FiGUre	FiGUre	NNP
cord-278081-tk7vn1v1	118	14	1	1	CD
cord-278081-tk7vn1v1	118	15	|	|	NNP
cord-278081-tk7vn1v1	118	16	Nucleolar	Nucleolar	NNP
cord-278081-tk7vn1v1	118	17	integrity	integrity	NN
cord-278081-tk7vn1v1	118	18	from	from	IN
cord-278081-tk7vn1v1	118	19	RNA	RNA	NNP
cord-278081-tk7vn1v1	118	20	pol	pol	NN
cord-278081-tk7vn1v1	118	21	II	II	NNP
cord-278081-tk7vn1v1	118	22	intronic	intronic	NNP
cord-278081-tk7vn1v1	118	23	Alu	Alu	NNP
cord-278081-tk7vn1v1	118	24	sequences	sequence	NNS
cord-278081-tk7vn1v1	118	25	.	.	.
cord-278081-tk7vn1v1	119	1	(	(	-LRB-
cord-278081-tk7vn1v1	119	2	a	a	LS
cord-278081-tk7vn1v1	119	3	)	)	-RRB-
cord-278081-tk7vn1v1	119	4	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	119	5	-	-	HYPH
cord-278081-tk7vn1v1	119	6	Herger	Herger	NNP
cord-278081-tk7vn1v1	119	7	and	and	CC
cord-278081-tk7vn1v1	119	8	colleagues	colleague	NNS
cord-278081-tk7vn1v1	119	9	reported	report	VBD
cord-278081-tk7vn1v1	119	10	that	that	IN
cord-278081-tk7vn1v1	119	11	the	the	DT
cord-278081-tk7vn1v1	119	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	119	13	has	have	VBZ
cord-278081-tk7vn1v1	119	14	a	a	DT
cord-278081-tk7vn1v1	119	15	high	high	JJ
cord-278081-tk7vn1v1	119	16	content	content	NN
cord-278081-tk7vn1v1	119	17	of	of	IN
cord-278081-tk7vn1v1	119	18	RNA	RNA	NNP
cord-278081-tk7vn1v1	119	19	pol	pol	NN
cord-278081-tk7vn1v1	119	20	II	II	NNP
cord-278081-tk7vn1v1	119	21	transcripts	transcript	NNS
cord-278081-tk7vn1v1	119	22	with	with	IN
cord-278081-tk7vn1v1	119	23	intronic	intronic	NNP
cord-278081-tk7vn1v1	119	24	Alu	Alu	NNP
cord-278081-tk7vn1v1	119	25	sequences	sequence	NNS
cord-278081-tk7vn1v1	119	26	(	(	-LRB-
cord-278081-tk7vn1v1	119	27	red	red	NNP
cord-278081-tk7vn1v1	119	28	)	)	-RRB-
cord-278081-tk7vn1v1	119	29	and	and	CC
cord-278081-tk7vn1v1	119	30	these	these	DT
cord-278081-tk7vn1v1	119	31	transcripts	transcript	NNS
cord-278081-tk7vn1v1	119	32	associate	associate	VBP
cord-278081-tk7vn1v1	119	33	with	with	IN
cord-278081-tk7vn1v1	119	34	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	119	35	to	to	TO
cord-278081-tk7vn1v1	119	36	maintain	maintain	VB
cord-278081-tk7vn1v1	119	37	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	119	38	integrity	integrity	NN
cord-278081-tk7vn1v1	119	39	(	(	-LRB-
cord-278081-tk7vn1v1	119	40	59	59	CD
cord-278081-tk7vn1v1	119	41	)	)	-RRB-
cord-278081-tk7vn1v1	119	42	.	.	.
cord-278081-tk7vn1v1	120	1	(	(	-LRB-
cord-278081-tk7vn1v1	120	2	Since	since	IN
cord-278081-tk7vn1v1	120	3	the	the	DT
cord-278081-tk7vn1v1	120	4	actual	actual	JJ
cord-278081-tk7vn1v1	120	5	localization	localization	NN
cord-278081-tk7vn1v1	120	6	in	in	IN
cord-278081-tk7vn1v1	120	7	the	the	DT
cord-278081-tk7vn1v1	120	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	120	9	and	and	CC
cord-278081-tk7vn1v1	120	10	structure	structure	NN
cord-278081-tk7vn1v1	120	11	of	of	IN
cord-278081-tk7vn1v1	120	12	the	the	DT
cord-278081-tk7vn1v1	120	13	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	120	14	-	-	HYPH
cord-278081-tk7vn1v1	120	15	RNA	RNA	NNP
cord-278081-tk7vn1v1	120	16	complexes	complex	NNS
cord-278081-tk7vn1v1	120	17	are	be	VBP
cord-278081-tk7vn1v1	120	18	not	not	RB
cord-278081-tk7vn1v1	120	19	known	know	VBN
cord-278081-tk7vn1v1	120	20	,	,	,
cord-278081-tk7vn1v1	120	21	they	-PRON-	PRP
cord-278081-tk7vn1v1	120	22	are	be	VBP
cord-278081-tk7vn1v1	120	23	shown	show	VBN
cord-278081-tk7vn1v1	120	24	simply	simply	RB
cord-278081-tk7vn1v1	120	25	as	as	IN
cord-278081-tk7vn1v1	120	26	part	part	NN
cord-278081-tk7vn1v1	120	27	of	of	IN
cord-278081-tk7vn1v1	120	28	the	the	DT
cord-278081-tk7vn1v1	120	29	nucleolar	nucleolar	NNP
cord-278081-tk7vn1v1	120	30	perimeter	perimeter	NN
cord-278081-tk7vn1v1	120	31	.	.	.
cord-278081-tk7vn1v1	120	32	)	)	-RRB-
cord-278081-tk7vn1v1	121	1	(	(	-LRB-
cord-278081-tk7vn1v1	121	2	b	b	LS
cord-278081-tk7vn1v1	121	3	)	)	-RRB-
cord-278081-tk7vn1v1	121	4	Addition	addition	NN
cord-278081-tk7vn1v1	121	5	of	of	IN
cord-278081-tk7vn1v1	121	6	RNA	RNA	NNP
cord-278081-tk7vn1v1	121	7	fragments	fragment	NNS
cord-278081-tk7vn1v1	121	8	from	from	IN
cord-278081-tk7vn1v1	121	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	121	10	pol	pol	NN
cord-278081-tk7vn1v1	121	11	III	III	NNP
cord-278081-tk7vn1v1	121	12	Alu	Alu	NNP
cord-278081-tk7vn1v1	121	13	sequences	sequence	NNS
cord-278081-tk7vn1v1	121	14	,	,	,
cord-278081-tk7vn1v1	121	15	even	even	RB
cord-278081-tk7vn1v1	121	16	as	as	RB
cord-278081-tk7vn1v1	121	17	short	short	JJ
cord-278081-tk7vn1v1	121	18	as	as	IN
cord-278081-tk7vn1v1	121	19	20	20	CD
cord-278081-tk7vn1v1	121	20	bases	basis	NNS
cord-278081-tk7vn1v1	121	21	,	,	,
cord-278081-tk7vn1v1	121	22	leads	lead	VBZ
cord-278081-tk7vn1v1	121	23	to	to	IN
cord-278081-tk7vn1v1	121	24	loss	loss	NN
cord-278081-tk7vn1v1	121	25	of	of	IN
cord-278081-tk7vn1v1	121	26	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	121	27	integrity	integrity	NN
cord-278081-tk7vn1v1	121	28	which	which	WDT
cord-278081-tk7vn1v1	121	29	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	121	30	-	-	HYPH
cord-278081-tk7vn1v1	121	31	Herger	Herger	NNP
cord-278081-tk7vn1v1	121	32	and	and	CC
cord-278081-tk7vn1v1	121	33	colleagues	colleague	NNS
cord-278081-tk7vn1v1	121	34	attribute	attribute	VBP
cord-278081-tk7vn1v1	121	35	to	to	IN
cord-278081-tk7vn1v1	121	36	Dicer	Dicer	NNP
cord-278081-tk7vn1v1	121	37	degradation	degradation	NN
cord-278081-tk7vn1v1	121	38	of	of	IN
cord-278081-tk7vn1v1	121	39	hybridized	hybridize	VBN
cord-278081-tk7vn1v1	121	40	Alu	Alu	NNP
cord-278081-tk7vn1v1	121	41	sequences	sequence	NNS
cord-278081-tk7vn1v1	121	42	.	.	.
cord-278081-tk7vn1v1	122	1	This	this	DT
cord-278081-tk7vn1v1	122	2	leads	lead	VBZ
cord-278081-tk7vn1v1	122	3	to	to	IN
cord-278081-tk7vn1v1	122	4	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	122	5	of	of	IN
cord-278081-tk7vn1v1	122	6	the	the	DT
cord-278081-tk7vn1v1	122	7	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	122	8	into	into	IN
cord-278081-tk7vn1v1	122	9	subunits	subunit	NNS
cord-278081-tk7vn1v1	122	10	that	that	WDT
cord-278081-tk7vn1v1	122	11	are	be	VBP
cord-278081-tk7vn1v1	122	12	substantially	substantially	RB
cord-278081-tk7vn1v1	122	13	less	less	RBR
cord-278081-tk7vn1v1	122	14	efficient	efficient	JJ
cord-278081-tk7vn1v1	122	15	in	in	IN
cord-278081-tk7vn1v1	122	16	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	122	17	functions	function	NNS
cord-278081-tk7vn1v1	122	18	of	of	IN
cord-278081-tk7vn1v1	122	19	RNA	RNA	NNP
cord-278081-tk7vn1v1	122	20	folding	folding	NN
cord-278081-tk7vn1v1	122	21	and	and	CC
cord-278081-tk7vn1v1	122	22	ribonucleoprotein	ribonucleoprotein	NNP
cord-278081-tk7vn1v1	122	23	assembly	assembly	NN
cord-278081-tk7vn1v1	122	24	.	.	.
cord-278081-tk7vn1v1	123	1	combined	combine	VBN
cord-278081-tk7vn1v1	123	2	,	,	,
cord-278081-tk7vn1v1	123	3	they	-PRON-	PRP
cord-278081-tk7vn1v1	123	4	can	can	MD
cord-278081-tk7vn1v1	123	5	occupy	occupy	VB
cord-278081-tk7vn1v1	123	6	up	up	IN
cord-278081-tk7vn1v1	123	7	to	to	TO
cord-278081-tk7vn1v1	123	8	25	25	CD
cord-278081-tk7vn1v1	123	9	%	%	NN
cord-278081-tk7vn1v1	123	10	of	of	IN
cord-278081-tk7vn1v1	123	11	the	the	DT
cord-278081-tk7vn1v1	123	12	nucleus	nucleus	NN
cord-278081-tk7vn1v1	123	13	.	.	.
cord-278081-tk7vn1v1	124	1	They	-PRON-	PRP
cord-278081-tk7vn1v1	124	2	can	can	MD
cord-278081-tk7vn1v1	124	3	expand	expand	VB
cord-278081-tk7vn1v1	124	4	rapidly	rapidly	RB
cord-278081-tk7vn1v1	124	5	,	,	,
cord-278081-tk7vn1v1	124	6	facilitated	facilitate	VBN
cord-278081-tk7vn1v1	124	7	by	by	IN
cord-278081-tk7vn1v1	124	8	increased	increase	VBN
cord-278081-tk7vn1v1	124	9	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	124	10	,	,	,
cord-278081-tk7vn1v1	124	11	in	in	IN
cord-278081-tk7vn1v1	124	12	response	response	NN
cord-278081-tk7vn1v1	124	13	to	to	IN
cord-278081-tk7vn1v1	124	14	cellular	cellular	JJ
cord-278081-tk7vn1v1	124	15	stress	stress	NN
cord-278081-tk7vn1v1	124	16	since	since	IN
cord-278081-tk7vn1v1	124	17	the	the	DT
cord-278081-tk7vn1v1	124	18	cell	cell	NN
cord-278081-tk7vn1v1	124	19	may	may	MD
cord-278081-tk7vn1v1	124	20	need	need	VB
cord-278081-tk7vn1v1	124	21	to	to	TO
cord-278081-tk7vn1v1	124	22	have	have	VB
cord-278081-tk7vn1v1	124	23	more	more	JJR
cord-278081-tk7vn1v1	124	24	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	124	25	and	and	CC
cord-278081-tk7vn1v1	124	26	tRNAs	trna	NNS
cord-278081-tk7vn1v1	124	27	to	to	TO
cord-278081-tk7vn1v1	124	28	synthesize	synthesize	VB
cord-278081-tk7vn1v1	124	29	new	new	JJ
cord-278081-tk7vn1v1	124	30	proteins	protein	NNS
cord-278081-tk7vn1v1	124	31	to	to	TO
cord-278081-tk7vn1v1	124	32	recover	recover	VB
cord-278081-tk7vn1v1	124	33	from	from	IN
cord-278081-tk7vn1v1	124	34	the	the	DT
cord-278081-tk7vn1v1	124	35	stress	stress	NN
cord-278081-tk7vn1v1	124	36	.	.	.
cord-278081-tk7vn1v1	125	1	However	however	RB
cord-278081-tk7vn1v1	125	2	,	,	,
cord-278081-tk7vn1v1	125	3	we	-PRON-	PRP
cord-278081-tk7vn1v1	125	4	should	should	MD
cord-278081-tk7vn1v1	125	5	remember	remember	VB
cord-278081-tk7vn1v1	125	6	that	that	IN
cord-278081-tk7vn1v1	125	7	the	the	DT
cord-278081-tk7vn1v1	125	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	125	9	surrounds	surround	VBZ
cord-278081-tk7vn1v1	125	10	itself	-PRON-	PRP
cord-278081-tk7vn1v1	125	11	with	with	IN
cord-278081-tk7vn1v1	125	12	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	126	1	so	so	CC
cord-278081-tk7vn1v1	126	2	there	there	EX
cord-278081-tk7vn1v1	126	3	is	be	VBZ
cord-278081-tk7vn1v1	126	4	the	the	DT
cord-278081-tk7vn1v1	126	5	possibility	possibility	NN
cord-278081-tk7vn1v1	126	6	of	of	IN
cord-278081-tk7vn1v1	126	7	displacement	displacement	NN
cord-278081-tk7vn1v1	126	8	or	or	CC
cord-278081-tk7vn1v1	126	9	disruption	disruption	NN
cord-278081-tk7vn1v1	126	10	of	of	IN
cord-278081-tk7vn1v1	126	11	neighboring	neighbor	VBG
cord-278081-tk7vn1v1	126	12	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	126	13	due	due	IN
cord-278081-tk7vn1v1	126	14	to	to	IN
cord-278081-tk7vn1v1	126	15	the	the	DT
cord-278081-tk7vn1v1	126	16	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	126	17	dynamics	dynamic	NNS
cord-278081-tk7vn1v1	126	18	(	(	-LRB-
cord-278081-tk7vn1v1	126	19	1	1	CD
cord-278081-tk7vn1v1	126	20	)	)	-RRB-
cord-278081-tk7vn1v1	126	21	.	.	.
cord-278081-tk7vn1v1	127	1	With	with	IN
cord-278081-tk7vn1v1	127	2	regards	regard	NNS
cord-278081-tk7vn1v1	127	3	to	to	IN
cord-278081-tk7vn1v1	127	4	the	the	DT
cord-278081-tk7vn1v1	127	5	cell	cell	NN
cord-278081-tk7vn1v1	127	6	cycle	cycle	NN
cord-278081-tk7vn1v1	127	7	,	,	,
cord-278081-tk7vn1v1	127	8	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	127	9	disappear	disappear	VBP
cord-278081-tk7vn1v1	127	10	in	in	IN
cord-278081-tk7vn1v1	127	11	mitosis	mitosis	NN
cord-278081-tk7vn1v1	127	12	and	and	CC
cord-278081-tk7vn1v1	127	13	reappear	reappear	VB
cord-278081-tk7vn1v1	127	14	in	in	IN
cord-278081-tk7vn1v1	127	15	telophase	telophase	NN
cord-278081-tk7vn1v1	127	16	and	and	CC
cord-278081-tk7vn1v1	127	17	early	early	JJ
cord-278081-tk7vn1v1	127	18	G1	G1	NNP
cord-278081-tk7vn1v1	127	19	forming	form	VBG
cord-278081-tk7vn1v1	127	20	around	around	RB
cord-278081-tk7vn1v1	127	21	NORs	nor	NNS
cord-278081-tk7vn1v1	127	22	with	with	IN
cord-278081-tk7vn1v1	127	23	the	the	DT
cord-278081-tk7vn1v1	127	24	rDNA	rDNA	NNP
cord-278081-tk7vn1v1	127	25	genes	gene	NNS
cord-278081-tk7vn1v1	127	26	and	and	CC
cord-278081-tk7vn1v1	127	27	pre	pre	JJ
cord-278081-tk7vn1v1	127	28	-	-	JJ
cord-278081-tk7vn1v1	127	29	existing	existing	JJ
cord-278081-tk7vn1v1	127	30	rRNA	rrna	NN
cord-278081-tk7vn1v1	127	31	and	and	CC
cord-278081-tk7vn1v1	127	32	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	127	33	complexes	complex	NNS
cord-278081-tk7vn1v1	127	34	(	(	-LRB-
cord-278081-tk7vn1v1	127	35	64	64	CD
cord-278081-tk7vn1v1	127	36	)	)	-RRB-
cord-278081-tk7vn1v1	127	37	.	.	.
cord-278081-tk7vn1v1	128	1	In	in	IN
cord-278081-tk7vn1v1	128	2	addition	addition	NN
cord-278081-tk7vn1v1	128	3	,	,	,
cord-278081-tk7vn1v1	128	4	CDK1	CDK1	NNP
cord-278081-tk7vn1v1	128	5	cyclin	cyclin	NN
cord-278081-tk7vn1v1	128	6	kinases	kinase	NNS
cord-278081-tk7vn1v1	128	7	have	have	VBP
cord-278081-tk7vn1v1	128	8	a	a	DT
cord-278081-tk7vn1v1	128	9	key	key	JJ
cord-278081-tk7vn1v1	128	10	role	role	NN
cord-278081-tk7vn1v1	128	11	in	in	IN
cord-278081-tk7vn1v1	128	12	controlling	control	VBG
cord-278081-tk7vn1v1	128	13	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	128	14	during	during	IN
cord-278081-tk7vn1v1	128	15	cell	cell	NN
cord-278081-tk7vn1v1	128	16	cycling	cycling	NN
cord-278081-tk7vn1v1	128	17	,	,	,
cord-278081-tk7vn1v1	128	18	and	and	CC
cord-278081-tk7vn1v1	128	19	centromere	centromere	NN
cord-278081-tk7vn1v1	128	20	complexes	complex	NNS
cord-278081-tk7vn1v1	128	21	are	be	VBP
cord-278081-tk7vn1v1	128	22	generated	generate	VBN
cord-278081-tk7vn1v1	128	23	in	in	IN
cord-278081-tk7vn1v1	128	24	the	the	DT
cord-278081-tk7vn1v1	128	25	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	128	26	giving	give	VBG
cord-278081-tk7vn1v1	128	27	further	further	JJ
cord-278081-tk7vn1v1	128	28	importance	importance	NN
cord-278081-tk7vn1v1	128	29	to	to	IN
cord-278081-tk7vn1v1	128	30	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	128	31	in	in	IN
cord-278081-tk7vn1v1	128	32	cell	cell	NN
cord-278081-tk7vn1v1	128	33	cycling	cycling	NN
cord-278081-tk7vn1v1	128	34	.	.	.
cord-278081-tk7vn1v1	129	1	Once	once	RB
cord-278081-tk7vn1v1	129	2	in	in	IN
cord-278081-tk7vn1v1	129	3	the	the	DT
cord-278081-tk7vn1v1	129	4	host	host	NN
cord-278081-tk7vn1v1	129	5	cell	cell	NN
cord-278081-tk7vn1v1	129	6	,	,	,
cord-278081-tk7vn1v1	129	7	the	the	DT
cord-278081-tk7vn1v1	129	8	virus	virus	NN
cord-278081-tk7vn1v1	129	9	can	can	MD
cord-278081-tk7vn1v1	129	10	be	be	VB
cord-278081-tk7vn1v1	129	11	sequestered	sequester	VBN
cord-278081-tk7vn1v1	129	12	into	into	IN
cord-278081-tk7vn1v1	129	13	the	the	DT
cord-278081-tk7vn1v1	129	14	host	host	NN
cord-278081-tk7vn1v1	129	15	chromatin	chromatin	NN
cord-278081-tk7vn1v1	129	16	or	or	CC
cord-278081-tk7vn1v1	129	17	it	-PRON-	PRP
cord-278081-tk7vn1v1	129	18	can	can	MD
cord-278081-tk7vn1v1	129	19	initiate	initiate	VB
cord-278081-tk7vn1v1	129	20	viral	viral	JJ
cord-278081-tk7vn1v1	129	21	replication	replication	NN
cord-278081-tk7vn1v1	129	22	.	.	.
cord-278081-tk7vn1v1	130	1	In	in	IN
cord-278081-tk7vn1v1	130	2	the	the	DT
cord-278081-tk7vn1v1	130	3	case	case	NN
cord-278081-tk7vn1v1	130	4	of	of	IN
cord-278081-tk7vn1v1	130	5	EBV	EBV	NNP
cord-278081-tk7vn1v1	130	6	,	,	,
cord-278081-tk7vn1v1	130	7	the	the	DT
cord-278081-tk7vn1v1	130	8	multi	multi	JJ
cord-278081-tk7vn1v1	130	9	-	-	JJ
cord-278081-tk7vn1v1	130	10	functional	functional	JJ
cord-278081-tk7vn1v1	130	11	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	130	12	-	-	HYPH
cord-278081-tk7vn1v1	130	13	Barr	Barr	NNP
cord-278081-tk7vn1v1	130	14	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	130	15	antigen	antigen	NN
cord-278081-tk7vn1v1	130	16	1	1	CD
cord-278081-tk7vn1v1	131	1	(	(	-LRB-
cord-278081-tk7vn1v1	131	2	EBNA-1	ebna-1	NN
cord-278081-tk7vn1v1	131	3	)	)	-RRB-
cord-278081-tk7vn1v1	131	4	protein	protein	NN
cord-278081-tk7vn1v1	131	5	from	from	IN
cord-278081-tk7vn1v1	131	6	the	the	DT
cord-278081-tk7vn1v1	131	7	EBV	EBV	NNP
cord-278081-tk7vn1v1	131	8	genome	genome	NN
cord-278081-tk7vn1v1	131	9	can	can	MD
cord-278081-tk7vn1v1	131	10	assist	assist	VB
cord-278081-tk7vn1v1	131	11	in	in	IN
cord-278081-tk7vn1v1	131	12	the	the	DT
cord-278081-tk7vn1v1	131	13	spread	spread	NN
cord-278081-tk7vn1v1	131	14	and	and	CC
cord-278081-tk7vn1v1	131	15	attachment	attachment	NN
cord-278081-tk7vn1v1	131	16	of	of	IN
cord-278081-tk7vn1v1	131	17	viral	viral	JJ
cord-278081-tk7vn1v1	131	18	DNA	dna	NN
cord-278081-tk7vn1v1	131	19	to	to	TO
cord-278081-tk7vn1v1	131	20	metaphase	metaphase	VB
cord-278081-tk7vn1v1	131	21	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	131	22	(	(	-LRB-
cord-278081-tk7vn1v1	131	23	65	65	CD
cord-278081-tk7vn1v1	131	24	)	)	-RRB-
cord-278081-tk7vn1v1	131	25	.	.	.
cord-278081-tk7vn1v1	132	1	EBNA-1	EBNA-1	NNP
cord-278081-tk7vn1v1	132	2	can	can	MD
cord-278081-tk7vn1v1	132	3	also	also	RB
cord-278081-tk7vn1v1	132	4	disrupt	disrupt	VB
cord-278081-tk7vn1v1	132	5	the	the	DT
cord-278081-tk7vn1v1	132	6	host	host	NN
cord-278081-tk7vn1v1	132	7	cell	cell	NN
cord-278081-tk7vn1v1	132	8	's	's	POS
cord-278081-tk7vn1v1	132	9	USP7-assisted	usp7-assiste	VBN
cord-278081-tk7vn1v1	132	10	stabilization	stabilization	NN
cord-278081-tk7vn1v1	132	11	of	of	IN
cord-278081-tk7vn1v1	132	12	p53/	p53/	CD
cord-278081-tk7vn1v1	132	13	TP53	TP53	NNP
cord-278081-tk7vn1v1	132	14	,	,	,
cord-278081-tk7vn1v1	132	15	thereby	thereby	RB
cord-278081-tk7vn1v1	132	16	preventing	prevent	VBG
cord-278081-tk7vn1v1	132	17	the	the	DT
cord-278081-tk7vn1v1	132	18	host	host	NN
cord-278081-tk7vn1v1	132	19	cell	cell	NN
cord-278081-tk7vn1v1	132	20	from	from	IN
cord-278081-tk7vn1v1	132	21	entering	enter	VBG
cord-278081-tk7vn1v1	132	22	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	132	23	,	,	,
cord-278081-tk7vn1v1	132	24	setting	set	VBG
cord-278081-tk7vn1v1	132	25	the	the	DT
cord-278081-tk7vn1v1	132	26	stage	stage	NN
cord-278081-tk7vn1v1	132	27	for	for	IN
cord-278081-tk7vn1v1	132	28	continual	continual	JJ
cord-278081-tk7vn1v1	132	29	viral	viral	JJ
cord-278081-tk7vn1v1	132	30	replication	replication	NN
cord-278081-tk7vn1v1	132	31	(	(	-LRB-
cord-278081-tk7vn1v1	132	32	65	65	CD
cord-278081-tk7vn1v1	132	33	)	)	-RRB-
cord-278081-tk7vn1v1	132	34	.	.	.
cord-278081-tk7vn1v1	133	1	However	however	RB
cord-278081-tk7vn1v1	133	2	,	,	,
cord-278081-tk7vn1v1	133	3	viruses	virus	NNS
cord-278081-tk7vn1v1	133	4	do	do	VBP
cord-278081-tk7vn1v1	133	5	need	need	VB
cord-278081-tk7vn1v1	133	6	host	host	NN
cord-278081-tk7vn1v1	133	7	cell	cell	NN
cord-278081-tk7vn1v1	133	8	machinery	machinery	NN
cord-278081-tk7vn1v1	133	9	produced	produce	VBN
cord-278081-tk7vn1v1	133	10	in	in	IN
cord-278081-tk7vn1v1	133	11	the	the	DT
cord-278081-tk7vn1v1	133	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	133	13	,	,	,
cord-278081-tk7vn1v1	133	14	such	such	JJ
cord-278081-tk7vn1v1	133	15	as	as	IN
cord-278081-tk7vn1v1	133	16	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	133	17	,	,	,
cord-278081-tk7vn1v1	133	18	to	to	TO
cord-278081-tk7vn1v1	133	19	facilitate	facilitate	VB
cord-278081-tk7vn1v1	133	20	viral	viral	JJ
cord-278081-tk7vn1v1	133	21	replication	replication	NN
cord-278081-tk7vn1v1	133	22	.	.	.
cord-278081-tk7vn1v1	134	1	Therefore	therefore	RB
cord-278081-tk7vn1v1	134	2	,	,	,
cord-278081-tk7vn1v1	134	3	the	the	DT
cord-278081-tk7vn1v1	134	4	virus	virus	NN
cord-278081-tk7vn1v1	134	5	will	will	MD
cord-278081-tk7vn1v1	134	6	attempt	attempt	VB
cord-278081-tk7vn1v1	134	7	to	to	TO
cord-278081-tk7vn1v1	134	8	increase	increase	VB
cord-278081-tk7vn1v1	134	9	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	134	10	activity	activity	NN
cord-278081-tk7vn1v1	134	11	and	and	CC
cord-278081-tk7vn1v1	134	12	turn	turn	VB
cord-278081-tk7vn1v1	134	13	on	on	RP
cord-278081-tk7vn1v1	134	14	viral	viral	JJ
cord-278081-tk7vn1v1	134	15	gene	gene	NN
cord-278081-tk7vn1v1	134	16	expression	expression	NN
cord-278081-tk7vn1v1	134	17	.	.	.
cord-278081-tk7vn1v1	135	1	The	the	DT
cord-278081-tk7vn1v1	135	2	EBV	EBV	NNP
cord-278081-tk7vn1v1	135	3	genome	genome	NN
cord-278081-tk7vn1v1	135	4	has	have	VBZ
cord-278081-tk7vn1v1	135	5	a	a	DT
cord-278081-tk7vn1v1	135	6	snoRNA	snoRNA	NNP
cord-278081-tk7vn1v1	135	7	,	,	,
cord-278081-tk7vn1v1	135	8	called	call	VBN
cord-278081-tk7vn1v1	135	9	v	v	NN
cord-278081-tk7vn1v1	135	10	-	-	:
cord-278081-tk7vn1v1	135	11	snoRNA1	snoRNA1	NNP
cord-278081-tk7vn1v1	135	12	,	,	,
cord-278081-tk7vn1v1	135	13	which	which	WDT
cord-278081-tk7vn1v1	135	14	is	be	VBZ
cord-278081-tk7vn1v1	135	15	found	find	VBN
cord-278081-tk7vn1v1	135	16	in	in	IN
cord-278081-tk7vn1v1	135	17	the	the	DT
cord-278081-tk7vn1v1	135	18	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	135	19	in	in	IN
cord-278081-tk7vn1v1	135	20	infected	infected	JJ
cord-278081-tk7vn1v1	135	21	cells	cell	NNS
cord-278081-tk7vn1v1	135	22	(	(	-LRB-
cord-278081-tk7vn1v1	135	23	66	66	CD
cord-278081-tk7vn1v1	135	24	)	)	-RRB-
cord-278081-tk7vn1v1	135	25	.	.	.
cord-278081-tk7vn1v1	136	1	The	the	DT
cord-278081-tk7vn1v1	136	2	v	v	NN
cord-278081-tk7vn1v1	136	3	-	-	:
cord-278081-tk7vn1v1	136	4	snoRNA1	snorna1	RB
cord-278081-tk7vn1v1	136	5	appears	appear	VBZ
cord-278081-tk7vn1v1	136	6	to	to	TO
cord-278081-tk7vn1v1	136	7	be	be	VB
cord-278081-tk7vn1v1	136	8	involved	involve	VBN
cord-278081-tk7vn1v1	136	9	in	in	IN
cord-278081-tk7vn1v1	136	10	activation	activation	NN
cord-278081-tk7vn1v1	136	11	of	of	IN
cord-278081-tk7vn1v1	136	12	the	the	DT
cord-278081-tk7vn1v1	136	13	viral	viral	JJ
cord-278081-tk7vn1v1	136	14	DNA	dna	NN
cord-278081-tk7vn1v1	136	15	polymerase	polymerase	NN
cord-278081-tk7vn1v1	136	16	.	.	.
cord-278081-tk7vn1v1	137	1	Another	another	DT
cord-278081-tk7vn1v1	137	2	EBV	EBV	NNP
cord-278081-tk7vn1v1	137	3	early	early	JJ
cord-278081-tk7vn1v1	137	4	gene	gene	NN
cord-278081-tk7vn1v1	137	5	is	be	VBZ
cord-278081-tk7vn1v1	137	6	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	137	7	-	-	HYPH
cord-278081-tk7vn1v1	137	8	Barr	Barr	NNP
cord-278081-tk7vn1v1	137	9	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	137	10	antigen	antigen	NN
cord-278081-tk7vn1v1	137	11	2	2	CD
cord-278081-tk7vn1v1	137	12	(	(	-LRB-
cord-278081-tk7vn1v1	137	13	EBNA-2	EBNA-2	NNP
cord-278081-tk7vn1v1	137	14	)	)	-RRB-
cord-278081-tk7vn1v1	137	15	which	which	WDT
cord-278081-tk7vn1v1	137	16	is	be	VBZ
cord-278081-tk7vn1v1	137	17	a	a	DT
cord-278081-tk7vn1v1	137	18	transactivator	transactivator	NN
cord-278081-tk7vn1v1	137	19	of	of	IN
cord-278081-tk7vn1v1	137	20	viral	viral	JJ
cord-278081-tk7vn1v1	137	21	and	and	CC
cord-278081-tk7vn1v1	137	22	host	host	NN
cord-278081-tk7vn1v1	137	23	genes	gene	NNS
cord-278081-tk7vn1v1	137	24	.	.	.
cord-278081-tk7vn1v1	138	1	EBNA-2	EBNA-2	NNP
cord-278081-tk7vn1v1	138	2	can	can	MD
cord-278081-tk7vn1v1	138	3	associate	associate	VB
cord-278081-tk7vn1v1	138	4	with	with	IN
cord-278081-tk7vn1v1	138	5	RNA	RNA	NNP
cord-278081-tk7vn1v1	138	6	polymerase	polymerase	NN
cord-278081-tk7vn1v1	138	7	II	II	NNP
cord-278081-tk7vn1v1	138	8	promoters	promoter	NNS
cord-278081-tk7vn1v1	138	9	to	to	TO
cord-278081-tk7vn1v1	138	10	induce	induce	VB
cord-278081-tk7vn1v1	138	11	increased	increase	VBN
cord-278081-tk7vn1v1	138	12	transcription	transcription	NN
cord-278081-tk7vn1v1	138	13	and	and	CC
cord-278081-tk7vn1v1	138	14	this	this	DT
cord-278081-tk7vn1v1	138	15	includes	include	VBZ
cord-278081-tk7vn1v1	138	16	the	the	DT
cord-278081-tk7vn1v1	138	17	MYC	MYC	NNP
cord-278081-tk7vn1v1	138	18	gene	gene	NN
cord-278081-tk7vn1v1	138	19	(	(	-LRB-
cord-278081-tk7vn1v1	138	20	67	67	CD
cord-278081-tk7vn1v1	138	21	,	,	,
cord-278081-tk7vn1v1	138	22	68	68	CD
cord-278081-tk7vn1v1	138	23	)	)	-RRB-
cord-278081-tk7vn1v1	138	24	.	.	.
cord-278081-tk7vn1v1	139	1	MYC	MYC	NNP
cord-278081-tk7vn1v1	139	2	induces	induce	VBZ
cord-278081-tk7vn1v1	139	3	increased	increase	VBN
cord-278081-tk7vn1v1	139	4	RNA	RNA	NNP
cord-278081-tk7vn1v1	139	5	polymerase	polymerase	NN
cord-278081-tk7vn1v1	139	6	III	III	NNP
cord-278081-tk7vn1v1	139	7	(	(	-LRB-
cord-278081-tk7vn1v1	139	8	RNA	RNA	NNP
cord-278081-tk7vn1v1	139	9	pol	pol	NN
cord-278081-tk7vn1v1	139	10	III	III	NNP
cord-278081-tk7vn1v1	139	11	)	)	-RRB-
cord-278081-tk7vn1v1	139	12	activity	activity	NN
cord-278081-tk7vn1v1	139	13	which	which	WDT
cord-278081-tk7vn1v1	139	14	creates	create	VBZ
cord-278081-tk7vn1v1	139	15	viral	viral	JJ
cord-278081-tk7vn1v1	139	16	RNA	RNA	NNP
cord-278081-tk7vn1v1	139	17	transcripts	transcript	NNS
cord-278081-tk7vn1v1	139	18	and	and	CC
cord-278081-tk7vn1v1	139	19	many	many	JJ
cord-278081-tk7vn1v1	139	20	of	of	IN
cord-278081-tk7vn1v1	139	21	the	the	DT
cord-278081-tk7vn1v1	139	22	RNA	RNA	NNP
cord-278081-tk7vn1v1	139	23	transcripts	transcript	NNS
cord-278081-tk7vn1v1	139	24	for	for	IN
cord-278081-tk7vn1v1	139	25	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	139	26	assembled	assemble	VBN
cord-278081-tk7vn1v1	139	27	complexes	complex	NNS
cord-278081-tk7vn1v1	139	28	(	(	-LRB-
cord-278081-tk7vn1v1	139	29	69	69	CD
cord-278081-tk7vn1v1	139	30	)	)	-RRB-
cord-278081-tk7vn1v1	139	31	.	.	.
cord-278081-tk7vn1v1	140	1	And	and	CC
cord-278081-tk7vn1v1	140	2	MYC	MYC	NNP
cord-278081-tk7vn1v1	140	3	induces	induce	VBZ
cord-278081-tk7vn1v1	140	4	increased	increase	VBN
cord-278081-tk7vn1v1	140	5	transcription	transcription	NN
cord-278081-tk7vn1v1	140	6	by	by	IN
cord-278081-tk7vn1v1	140	7	RNA	rna	NN
cord-278081-tk7vn1v1	140	8	pol	pol	NN
cord-278081-tk7vn1v1	140	9	I	-PRON-	PRP
cord-278081-tk7vn1v1	140	10	to	to	TO
cord-278081-tk7vn1v1	140	11	create	create	VB
cord-278081-tk7vn1v1	140	12	rRNA	rrna	NN
cord-278081-tk7vn1v1	140	13	transcripts	transcript	NNS
cord-278081-tk7vn1v1	140	14	(	(	-LRB-
cord-278081-tk7vn1v1	140	15	70	70	CD
cord-278081-tk7vn1v1	140	16	)	)	-RRB-
cord-278081-tk7vn1v1	140	17	.	.	.
cord-278081-tk7vn1v1	141	1	The	the	DT
cord-278081-tk7vn1v1	141	2	MYC	MYC	NNP
cord-278081-tk7vn1v1	141	3	interactome	interactome	NN
cord-278081-tk7vn1v1	141	4	consists	consist	VBZ
cord-278081-tk7vn1v1	141	5	of	of	IN
cord-278081-tk7vn1v1	141	6	approximately	approximately	RB
cord-278081-tk7vn1v1	141	7	15	15	CD
cord-278081-tk7vn1v1	141	8	%	%	NN
cord-278081-tk7vn1v1	141	9	of	of	IN
cord-278081-tk7vn1v1	141	10	genes	gene	NNS
cord-278081-tk7vn1v1	141	11	throughout	throughout	IN
cord-278081-tk7vn1v1	141	12	the	the	DT
cord-278081-tk7vn1v1	141	13	host	host	NN
cord-278081-tk7vn1v1	141	14	genome	genome	NN
cord-278081-tk7vn1v1	141	15	(	(	-LRB-
cord-278081-tk7vn1v1	141	16	71	71	CD
cord-278081-tk7vn1v1	141	17	,	,	,
cord-278081-tk7vn1v1	141	18	72	72	CD
cord-278081-tk7vn1v1	141	19	)	)	-RRB-
cord-278081-tk7vn1v1	141	20	.	.	.
cord-278081-tk7vn1v1	142	1	Included	include	VBN
cord-278081-tk7vn1v1	142	2	among	among	IN
cord-278081-tk7vn1v1	142	3	these	these	DT
cord-278081-tk7vn1v1	142	4	are	be	VBP
cord-278081-tk7vn1v1	142	5	genes	gene	NNS
cord-278081-tk7vn1v1	142	6	involved	involve	VBN
cord-278081-tk7vn1v1	142	7	in	in	IN
cord-278081-tk7vn1v1	142	8	polyamine	polyamine	NN
cord-278081-tk7vn1v1	142	9	synthesis	synthesis	NN
cord-278081-tk7vn1v1	142	10	:	:	:
cord-278081-tk7vn1v1	142	11	ornithine	ornithine	NN
cord-278081-tk7vn1v1	142	12	decarboxylase	decarboxylase	NNP
cord-278081-tk7vn1v1	142	13	(	(	-LRB-
cord-278081-tk7vn1v1	142	14	ODC	ODC	NNP
cord-278081-tk7vn1v1	142	15	)	)	-RRB-
cord-278081-tk7vn1v1	142	16	;	;	:
cord-278081-tk7vn1v1	143	1	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	143	2	synthase	synthase	NNP
cord-278081-tk7vn1v1	143	3	(	(	-LRB-
cord-278081-tk7vn1v1	143	4	SDS	SDS	NNP
cord-278081-tk7vn1v1	143	5	)	)	-RRB-
cord-278081-tk7vn1v1	143	6	;	;	:
cord-278081-tk7vn1v1	143	7	and	and	CC
cord-278081-tk7vn1v1	143	8	spermine	spermine	JJ
cord-278081-tk7vn1v1	143	9	synthase	synthase	NN
cord-278081-tk7vn1v1	143	10	(	(	-LRB-
cord-278081-tk7vn1v1	143	11	SMS	sms	NN
cord-278081-tk7vn1v1	143	12	)	)	-RRB-
cord-278081-tk7vn1v1	143	13	(	(	-LRB-
cord-278081-tk7vn1v1	143	14	73	73	CD
cord-278081-tk7vn1v1	143	15	)	)	-RRB-
cord-278081-tk7vn1v1	143	16	(	(	-LRB-
cord-278081-tk7vn1v1	143	17	74	74	CD
cord-278081-tk7vn1v1	143	18	)	)	-RRB-
cord-278081-tk7vn1v1	143	19	(	(	-LRB-
cord-278081-tk7vn1v1	143	20	75	75	CD
cord-278081-tk7vn1v1	143	21	)	)	-RRB-
cord-278081-tk7vn1v1	143	22	.	.	.
cord-278081-tk7vn1v1	144	1	And	and	CC
cord-278081-tk7vn1v1	144	2	so	so	RB
cord-278081-tk7vn1v1	144	3	the	the	DT
cord-278081-tk7vn1v1	144	4	virus	virus	NN
cord-278081-tk7vn1v1	144	5	induces	induce	VBZ
cord-278081-tk7vn1v1	144	6	polyamine	polyamine	NN
cord-278081-tk7vn1v1	144	7	synthesis	synthesis	NN
cord-278081-tk7vn1v1	144	8	which	which	WDT
cord-278081-tk7vn1v1	144	9	is	be	VBZ
cord-278081-tk7vn1v1	144	10	directly	directly	RB
cord-278081-tk7vn1v1	144	11	associated	associate	VBN
cord-278081-tk7vn1v1	144	12	with	with	IN
cord-278081-tk7vn1v1	144	13	an	an	DT
cord-278081-tk7vn1v1	144	14	increase	increase	NN
cord-278081-tk7vn1v1	144	15	in	in	IN
cord-278081-tk7vn1v1	144	16	the	the	DT
cord-278081-tk7vn1v1	144	17	size	size	NN
cord-278081-tk7vn1v1	144	18	and	and	CC
cord-278081-tk7vn1v1	144	19	activity	activity	NN
cord-278081-tk7vn1v1	144	20	of	of	IN
cord-278081-tk7vn1v1	144	21	the	the	DT
cord-278081-tk7vn1v1	144	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	144	23	(	(	-LRB-
cord-278081-tk7vn1v1	144	24	63	63	CD
cord-278081-tk7vn1v1	144	25	,	,	,
cord-278081-tk7vn1v1	144	26	76	76	CD
cord-278081-tk7vn1v1	144	27	)	)	-RRB-
cord-278081-tk7vn1v1	144	28	.	.	.
cord-278081-tk7vn1v1	145	1	The	the	DT
cord-278081-tk7vn1v1	145	2	cationic	cationic	JJ
cord-278081-tk7vn1v1	145	3	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	145	4	are	be	VBP
cord-278081-tk7vn1v1	145	5	ubiquitous	ubiquitous	JJ
cord-278081-tk7vn1v1	145	6	and	and	CC
cord-278081-tk7vn1v1	145	7	have	have	VBP
cord-278081-tk7vn1v1	145	8	many	many	JJ
cord-278081-tk7vn1v1	145	9	important	important	JJ
cord-278081-tk7vn1v1	145	10	interactions	interaction	NNS
cord-278081-tk7vn1v1	145	11	throughout	throughout	IN
cord-278081-tk7vn1v1	145	12	the	the	DT
cord-278081-tk7vn1v1	145	13	cell	cell	NN
cord-278081-tk7vn1v1	145	14	and	and	CC
cord-278081-tk7vn1v1	145	15	local	local	JJ
cord-278081-tk7vn1v1	145	16	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	145	17	environment	environment	NN
cord-278081-tk7vn1v1	145	18	(	(	-LRB-
cord-278081-tk7vn1v1	145	19	e.g.	e.g.	RB
cord-278081-tk7vn1v1	145	20	,	,	,
cord-278081-tk7vn1v1	145	21	spermine	spermine	JJ
cord-278081-tk7vn1v1	145	22	in	in	IN
cord-278081-tk7vn1v1	145	23	neural	neural	JJ
cord-278081-tk7vn1v1	145	24	synapses	synapsis	NNS
cord-278081-tk7vn1v1	145	25	)	)	-RRB-
cord-278081-tk7vn1v1	145	26	.	.	.
cord-278081-tk7vn1v1	146	1	The	the	DT
cord-278081-tk7vn1v1	146	2	highest	high	JJS
cord-278081-tk7vn1v1	146	3	levels	level	NNS
cord-278081-tk7vn1v1	146	4	of	of	IN
cord-278081-tk7vn1v1	146	5	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	146	6	are	be	VBP
cord-278081-tk7vn1v1	146	7	found	find	VBN
cord-278081-tk7vn1v1	146	8	in	in	IN
cord-278081-tk7vn1v1	146	9	the	the	DT
cord-278081-tk7vn1v1	146	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	146	11	where	where	WRB
cord-278081-tk7vn1v1	146	12	the	the	DT
cord-278081-tk7vn1v1	146	13	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	146	14	play	play	VBP
cord-278081-tk7vn1v1	146	15	a	a	DT
cord-278081-tk7vn1v1	146	16	critical	critical	JJ
cord-278081-tk7vn1v1	146	17	role	role	NN
cord-278081-tk7vn1v1	146	18	in	in	IN
cord-278081-tk7vn1v1	146	19	RNA	RNA	NNP
cord-278081-tk7vn1v1	146	20	folding	folding	NN
cord-278081-tk7vn1v1	146	21	by	by	IN
cord-278081-tk7vn1v1	146	22	neutralizing	neutralize	VBG
cord-278081-tk7vn1v1	146	23	anionic	anionic	JJ
cord-278081-tk7vn1v1	146	24	charges	charge	NNS
cord-278081-tk7vn1v1	146	25	in	in	IN
cord-278081-tk7vn1v1	146	26	the	the	DT
cord-278081-tk7vn1v1	146	27	RNA	RNA	NNP
cord-278081-tk7vn1v1	146	28	sufficiently	sufficiently	RB
cord-278081-tk7vn1v1	146	29	for	for	IN
cord-278081-tk7vn1v1	146	30	intra	intra	JJ
cord-278081-tk7vn1v1	146	31	-	-	JJ
cord-278081-tk7vn1v1	146	32	strand	strand	JJ
cord-278081-tk7vn1v1	146	33	RNA	RNA	NNP
cord-278081-tk7vn1v1	146	34	-	-	HYPH
cord-278081-tk7vn1v1	146	35	RNA	RNA	NNP
cord-278081-tk7vn1v1	146	36	interactions	interaction	NNS
cord-278081-tk7vn1v1	146	37	to	to	TO
cord-278081-tk7vn1v1	146	38	form	form	VB
cord-278081-tk7vn1v1	146	39	.	.	.
cord-278081-tk7vn1v1	147	1	Polyamine	polyamine	NN
cord-278081-tk7vn1v1	147	2	availability	availability	NN
cord-278081-tk7vn1v1	147	3	directly	directly	RB
cord-278081-tk7vn1v1	147	4	correlates	correlate	VBZ
cord-278081-tk7vn1v1	147	5	with	with	IN
cord-278081-tk7vn1v1	147	6	increased	increase	VBN
cord-278081-tk7vn1v1	147	7	RNA	RNA	NNP
cord-278081-tk7vn1v1	147	8	expression	expression	NN
cord-278081-tk7vn1v1	147	9	and	and	CC
cord-278081-tk7vn1v1	147	10	processing	processing	NN
cord-278081-tk7vn1v1	147	11	(	(	-LRB-
cord-278081-tk7vn1v1	147	12	77	77	CD
cord-278081-tk7vn1v1	147	13	)	)	-RRB-
cord-278081-tk7vn1v1	147	14	.	.	.
cord-278081-tk7vn1v1	148	1	And	and	CC
cord-278081-tk7vn1v1	148	2	the	the	DT
cord-278081-tk7vn1v1	148	3	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	148	4	can	can	MD
cord-278081-tk7vn1v1	148	5	assist	assist	VB
cord-278081-tk7vn1v1	148	6	in	in	IN
cord-278081-tk7vn1v1	148	7	RNP	RNP	NNP
cord-278081-tk7vn1v1	148	8	complex	complex	JJ
cord-278081-tk7vn1v1	148	9	assembly	assembly	NN
cord-278081-tk7vn1v1	148	10	.	.	.
cord-278081-tk7vn1v1	149	1	Mostly	mostly	RB
cord-278081-tk7vn1v1	149	2	these	these	DT
cord-278081-tk7vn1v1	149	3	are	be	VBP
cord-278081-tk7vn1v1	149	4	transient	transient	JJ
cord-278081-tk7vn1v1	149	5	interactions	interaction	NNS
cord-278081-tk7vn1v1	149	6	of	of	IN
cord-278081-tk7vn1v1	149	7	the	the	DT
cord-278081-tk7vn1v1	149	8	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	149	9	but	but	CC
cord-278081-tk7vn1v1	149	10	,	,	,
cord-278081-tk7vn1v1	149	11	in	in	IN
cord-278081-tk7vn1v1	149	12	some	some	DT
cord-278081-tk7vn1v1	149	13	cases	case	NNS
cord-278081-tk7vn1v1	149	14	,	,	,
cord-278081-tk7vn1v1	149	15	(	(	-LRB-
cord-278081-tk7vn1v1	149	16	a	a	LS
cord-278081-tk7vn1v1	149	17	)	)	-RRB-
cord-278081-tk7vn1v1	149	18	The	the	DT
cord-278081-tk7vn1v1	149	19	inactive	inactive	JJ
cord-278081-tk7vn1v1	149	20	X	x	NN
cord-278081-tk7vn1v1	149	21	chromosome	chromosome	NN
cord-278081-tk7vn1v1	149	22	(	(	-LRB-
cord-278081-tk7vn1v1	149	23	Xi	Xi	NNP
cord-278081-tk7vn1v1	149	24	)	)	-RRB-
cord-278081-tk7vn1v1	149	25	is	be	VBZ
cord-278081-tk7vn1v1	149	26	typically	typically	RB
cord-278081-tk7vn1v1	149	27	located	locate	VBN
cord-278081-tk7vn1v1	149	28	at	at	IN
cord-278081-tk7vn1v1	149	29	the	the	DT
cord-278081-tk7vn1v1	149	30	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	149	31	periphery	periphery	NN
cord-278081-tk7vn1v1	149	32	next	next	RB
cord-278081-tk7vn1v1	149	33	to	to	IN
cord-278081-tk7vn1v1	149	34	the	the	DT
cord-278081-tk7vn1v1	149	35	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	149	36	membrane	membrane	NN
cord-278081-tk7vn1v1	149	37	and	and	CC
cord-278081-tk7vn1v1	149	38	is	be	VBZ
cord-278081-tk7vn1v1	149	39	associated	associate	VBN
cord-278081-tk7vn1v1	149	40	with	with	IN
cord-278081-tk7vn1v1	149	41	a	a	DT
cord-278081-tk7vn1v1	149	42	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	149	43	in	in	IN
cord-278081-tk7vn1v1	149	44	90	90	CD
cord-278081-tk7vn1v1	149	45	%	%	NN
cord-278081-tk7vn1v1	149	46	of	of	IN
cord-278081-tk7vn1v1	149	47	cells	cell	NNS
cord-278081-tk7vn1v1	149	48	in	in	IN
cord-278081-tk7vn1v1	149	49	S	s	NN
cord-278081-tk7vn1v1	149	50	phase	phase	NN
cord-278081-tk7vn1v1	149	51	and	and	CC
cord-278081-tk7vn1v1	149	52	one	one	CD
cord-278081-tk7vn1v1	149	53	-	-	HYPH
cord-278081-tk7vn1v1	149	54	third	third	NN
cord-278081-tk7vn1v1	149	55	of	of	IN
cord-278081-tk7vn1v1	149	56	cells	cell	NNS
cord-278081-tk7vn1v1	149	57	throughout	throughout	IN
cord-278081-tk7vn1v1	149	58	the	the	DT
cord-278081-tk7vn1v1	149	59	cell	cell	NN
cord-278081-tk7vn1v1	149	60	cycle	cycle	NN
cord-278081-tk7vn1v1	149	61	except	except	IN
cord-278081-tk7vn1v1	149	62	during	during	IN
cord-278081-tk7vn1v1	149	63	mitosis	mitosis	NN
cord-278081-tk7vn1v1	149	64	when	when	WRB
cord-278081-tk7vn1v1	149	65	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	149	66	disappear	disappear	VBP
cord-278081-tk7vn1v1	149	67	(	(	-LRB-
cord-278081-tk7vn1v1	149	68	57	57	CD
cord-278081-tk7vn1v1	149	69	)	)	-RRB-
cord-278081-tk7vn1v1	149	70	.	.	.
cord-278081-tk7vn1v1	150	1	This	this	DT
cord-278081-tk7vn1v1	150	2	places	place	VBZ
cord-278081-tk7vn1v1	150	3	one	one	CD
cord-278081-tk7vn1v1	150	4	of	of	IN
cord-278081-tk7vn1v1	150	5	the	the	DT
cord-278081-tk7vn1v1	150	6	most	most	RBS
cord-278081-tk7vn1v1	150	7	inactive	inactive	JJ
cord-278081-tk7vn1v1	150	8	structures	structure	NNS
cord-278081-tk7vn1v1	150	9	in	in	IN
cord-278081-tk7vn1v1	150	10	the	the	DT
cord-278081-tk7vn1v1	150	11	cell	cell	NN
cord-278081-tk7vn1v1	150	12	,	,	,
cord-278081-tk7vn1v1	150	13	the	the	DT
cord-278081-tk7vn1v1	150	14	inactive	inactive	JJ
cord-278081-tk7vn1v1	150	15	X	X	NNP
cord-278081-tk7vn1v1	150	16	,	,	,
cord-278081-tk7vn1v1	150	17	next	next	JJ
cord-278081-tk7vn1v1	150	18	to	to	IN
cord-278081-tk7vn1v1	150	19	one	one	CD
cord-278081-tk7vn1v1	150	20	of	of	IN
cord-278081-tk7vn1v1	150	21	the	the	DT
cord-278081-tk7vn1v1	150	22	most	most	RBS
cord-278081-tk7vn1v1	150	23	active	active	JJ
cord-278081-tk7vn1v1	150	24	,	,	,
cord-278081-tk7vn1v1	150	25	multi	multi	JJ
cord-278081-tk7vn1v1	150	26	-	-	JJ
cord-278081-tk7vn1v1	150	27	functional	functional	JJ
cord-278081-tk7vn1v1	150	28	,	,	,
cord-278081-tk7vn1v1	150	29	and	and	CC
cord-278081-tk7vn1v1	150	30	dynamic	dynamic	JJ
cord-278081-tk7vn1v1	150	31	structures	structure	NNS
cord-278081-tk7vn1v1	150	32	,	,	,
cord-278081-tk7vn1v1	150	33	the	the	DT
cord-278081-tk7vn1v1	150	34	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	150	35	.	.	.
cord-278081-tk7vn1v1	151	1	(	(	-LRB-
cord-278081-tk7vn1v1	151	2	b	b	NN
cord-278081-tk7vn1v1	151	3	)	)	-RRB-
cord-278081-tk7vn1v1	152	1	The	the	DT
cord-278081-tk7vn1v1	152	2	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	152	3	can	can	MD
cord-278081-tk7vn1v1	152	4	rapidly	rapidly	RB
cord-278081-tk7vn1v1	152	5	expand	expand	VB
cord-278081-tk7vn1v1	152	6	during	during	IN
cord-278081-tk7vn1v1	152	7	cellular	cellular	JJ
cord-278081-tk7vn1v1	152	8	stress	stress	NN
cord-278081-tk7vn1v1	152	9	,	,	,
cord-278081-tk7vn1v1	152	10	such	such	JJ
cord-278081-tk7vn1v1	152	11	as	as	IN
cord-278081-tk7vn1v1	152	12	viral	viral	JJ
cord-278081-tk7vn1v1	152	13	activation	activation	NN
cord-278081-tk7vn1v1	152	14	.	.	.
cord-278081-tk7vn1v1	153	1	Trapped	trap	VBN
cord-278081-tk7vn1v1	153	2	between	between	IN
cord-278081-tk7vn1v1	153	3	the	the	DT
cord-278081-tk7vn1v1	153	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	153	5	and	and	CC
cord-278081-tk7vn1v1	153	6	the	the	DT
cord-278081-tk7vn1v1	153	7	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	153	8	membrane	membrane	NN
cord-278081-tk7vn1v1	153	9	,	,	,
cord-278081-tk7vn1v1	153	10	the	the	DT
cord-278081-tk7vn1v1	153	11	Xi	Xi	NNP
cord-278081-tk7vn1v1	153	12	could	could	MD
cord-278081-tk7vn1v1	153	13	be	be	VB
cord-278081-tk7vn1v1	153	14	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	153	15	by	by	IN
cord-278081-tk7vn1v1	153	16	the	the	DT
cord-278081-tk7vn1v1	153	17	expanding	expand	VBG
cord-278081-tk7vn1v1	153	18	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	153	19	.	.	.
cord-278081-tk7vn1v1	154	1	the	the	DT
cord-278081-tk7vn1v1	154	2	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	154	3	remain	remain	VBP
cord-278081-tk7vn1v1	154	4	as	as	IN
cord-278081-tk7vn1v1	154	5	part	part	NN
cord-278081-tk7vn1v1	154	6	of	of	IN
cord-278081-tk7vn1v1	154	7	the	the	DT
cord-278081-tk7vn1v1	154	8	final	final	JJ
cord-278081-tk7vn1v1	154	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	154	10	complex	complex	NN
cord-278081-tk7vn1v1	154	11	,	,	,
cord-278081-tk7vn1v1	154	12	such	such	JJ
cord-278081-tk7vn1v1	154	13	as	as	IN
cord-278081-tk7vn1v1	154	14	in	in	IN
cord-278081-tk7vn1v1	154	15	tRNAs	trna	NNS
cord-278081-tk7vn1v1	154	16	(	(	-LRB-
cord-278081-tk7vn1v1	154	17	1	1	CD
cord-278081-tk7vn1v1	154	18	)	)	-RRB-
cord-278081-tk7vn1v1	154	19	.	.	.
cord-278081-tk7vn1v1	155	1	Since	since	IN
cord-278081-tk7vn1v1	155	2	viral	viral	JJ
cord-278081-tk7vn1v1	155	3	genes	gene	NNS
cord-278081-tk7vn1v1	155	4	need	need	VBP
cord-278081-tk7vn1v1	155	5	to	to	TO
cord-278081-tk7vn1v1	155	6	be	be	VB
cord-278081-tk7vn1v1	155	7	expressed	express	VBN
cord-278081-tk7vn1v1	155	8	and	and	CC
cord-278081-tk7vn1v1	155	9	viral	viral	JJ
cord-278081-tk7vn1v1	155	10	RNAs	rna	NNS
cord-278081-tk7vn1v1	155	11	need	need	VBP
cord-278081-tk7vn1v1	155	12	to	to	TO
cord-278081-tk7vn1v1	155	13	be	be	VB
cord-278081-tk7vn1v1	155	14	folded	fold	VBN
cord-278081-tk7vn1v1	155	15	and	and	CC
cord-278081-tk7vn1v1	155	16	some	some	DT
cord-278081-tk7vn1v1	155	17	viral	viral	JJ
cord-278081-tk7vn1v1	155	18	proteins	protein	NNS
cord-278081-tk7vn1v1	155	19	localize	localize	VBP
cord-278081-tk7vn1v1	155	20	to	to	IN
cord-278081-tk7vn1v1	155	21	the	the	DT
cord-278081-tk7vn1v1	155	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	155	23	for	for	IN
cord-278081-tk7vn1v1	155	24	folding	folding	NN
cord-278081-tk7vn1v1	155	25	and	and	CC
cord-278081-tk7vn1v1	155	26	assembly	assembly	NN
cord-278081-tk7vn1v1	155	27	into	into	IN
cord-278081-tk7vn1v1	155	28	the	the	DT
cord-278081-tk7vn1v1	155	29	final	final	JJ
cord-278081-tk7vn1v1	155	30	virion	virion	NN
cord-278081-tk7vn1v1	155	31	,	,	,
cord-278081-tk7vn1v1	155	32	it	-PRON-	PRP
cord-278081-tk7vn1v1	155	33	is	be	VBZ
cord-278081-tk7vn1v1	155	34	understandable	understandable	JJ
cord-278081-tk7vn1v1	155	35	why	why	WRB
cord-278081-tk7vn1v1	155	36	a	a	DT
cord-278081-tk7vn1v1	155	37	virus	virus	NN
cord-278081-tk7vn1v1	155	38	would	would	MD
cord-278081-tk7vn1v1	155	39	want	want	VB
cord-278081-tk7vn1v1	155	40	to	to	TO
cord-278081-tk7vn1v1	155	41	increase	increase	VB
cord-278081-tk7vn1v1	155	42	the	the	DT
cord-278081-tk7vn1v1	155	43	host	host	NN
cord-278081-tk7vn1v1	155	44	cell	cell	NN
cord-278081-tk7vn1v1	155	45	's	's	POS
cord-278081-tk7vn1v1	155	46	polyamine	polyamine	NN
cord-278081-tk7vn1v1	155	47	content	content	NN
cord-278081-tk7vn1v1	155	48	to	to	TO
cord-278081-tk7vn1v1	155	49	increase	increase	VB
cord-278081-tk7vn1v1	155	50	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	155	51	capacity	capacity	NN
cord-278081-tk7vn1v1	155	52	and	and	CC
cord-278081-tk7vn1v1	155	53	activity	activity	NN
cord-278081-tk7vn1v1	155	54	(	(	-LRB-
cord-278081-tk7vn1v1	155	55	78	78	CD
cord-278081-tk7vn1v1	155	56	)	)	-RRB-
cord-278081-tk7vn1v1	155	57	.	.	.
cord-278081-tk7vn1v1	156	1	However	however	RB
cord-278081-tk7vn1v1	156	2	,	,	,
cord-278081-tk7vn1v1	156	3	the	the	DT
cord-278081-tk7vn1v1	156	4	relation	relation	NN
cord-278081-tk7vn1v1	156	5	between	between	IN
cord-278081-tk7vn1v1	156	6	viral	viral	JJ
cord-278081-tk7vn1v1	156	7	activation	activation	NN
cord-278081-tk7vn1v1	156	8	and	and	CC
cord-278081-tk7vn1v1	156	9	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	156	10	RNA	RNA	NNP
cord-278081-tk7vn1v1	156	11	synthesis	synthesis	NN
cord-278081-tk7vn1v1	156	12	is	be	VBZ
cord-278081-tk7vn1v1	156	13	more	more	RBR
cord-278081-tk7vn1v1	156	14	complex	complex	JJ
cord-278081-tk7vn1v1	156	15	and	and	CC
cord-278081-tk7vn1v1	156	16	can	can	MD
cord-278081-tk7vn1v1	156	17	vary	vary	VB
cord-278081-tk7vn1v1	156	18	among	among	IN
cord-278081-tk7vn1v1	156	19	viral	viral	JJ
cord-278081-tk7vn1v1	156	20	types	type	NNS
cord-278081-tk7vn1v1	156	21	.	.	.
cord-278081-tk7vn1v1	157	1	For	for	IN
cord-278081-tk7vn1v1	157	2	example	example	NN
cord-278081-tk7vn1v1	157	3	,	,	,
cord-278081-tk7vn1v1	157	4	poliovirus	poliovirus	NN
cord-278081-tk7vn1v1	157	5	inhibits	inhibit	VBZ
cord-278081-tk7vn1v1	157	6	RNA	rna	NN
cord-278081-tk7vn1v1	157	7	pol	pol	NN
cord-278081-tk7vn1v1	157	8	I	i	NN
cord-278081-tk7vn1v1	157	9	activity	activity	NN
cord-278081-tk7vn1v1	157	10	by	by	IN
cord-278081-tk7vn1v1	157	11	inducing	induce	VBG
cord-278081-tk7vn1v1	157	12	SL1	SL1	NNP
cord-278081-tk7vn1v1	157	13	cleavage	cleavage	NN
cord-278081-tk7vn1v1	157	14	and	and	CC
cord-278081-tk7vn1v1	157	15	UBF	UBF	NNP
cord-278081-tk7vn1v1	157	16	posttranslational	posttranslational	JJ
cord-278081-tk7vn1v1	157	17	modification	modification	NN
cord-278081-tk7vn1v1	157	18	(	(	-LRB-
cord-278081-tk7vn1v1	157	19	79	79	CD
cord-278081-tk7vn1v1	157	20	)	)	-RRB-
cord-278081-tk7vn1v1	157	21	,	,	,
cord-278081-tk7vn1v1	157	22	whereas	whereas	IN
cord-278081-tk7vn1v1	157	23	hepatitis	hepatitis	NNP
cord-278081-tk7vn1v1	157	24	C	C	NNP
cord-278081-tk7vn1v1	157	25	virus	virus	NN
cord-278081-tk7vn1v1	157	26	stimulates	stimulate	VBZ
cord-278081-tk7vn1v1	157	27	RNA	RNA	NNP
cord-278081-tk7vn1v1	157	28	pol	pol	NN
cord-278081-tk7vn1v1	157	29	I	i	NN
cord-278081-tk7vn1v1	157	30	activity	activity	NN
cord-278081-tk7vn1v1	157	31	which	which	WDT
cord-278081-tk7vn1v1	157	32	is	be	VBZ
cord-278081-tk7vn1v1	157	33	involved	involve	VBN
cord-278081-tk7vn1v1	157	34	in	in	IN
cord-278081-tk7vn1v1	157	35	transcription	transcription	NN
cord-278081-tk7vn1v1	157	36	of	of	IN
cord-278081-tk7vn1v1	157	37	the	the	DT
cord-278081-tk7vn1v1	157	38	rDNA	rDNA	NNP
cord-278081-tk7vn1v1	157	39	genes	gene	NNS
cord-278081-tk7vn1v1	157	40	(	(	-LRB-
cord-278081-tk7vn1v1	157	41	60	60	CD
cord-278081-tk7vn1v1	157	42	)	)	-RRB-
cord-278081-tk7vn1v1	157	43	.	.	.
cord-278081-tk7vn1v1	158	1	Viruses	virus	NNS
cord-278081-tk7vn1v1	158	2	can	can	MD
cord-278081-tk7vn1v1	158	3	influence	influence	VB
cord-278081-tk7vn1v1	158	4	the	the	DT
cord-278081-tk7vn1v1	158	5	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	158	6	proteome	proteome	NN
cord-278081-tk7vn1v1	158	7	leading	lead	VBG
cord-278081-tk7vn1v1	158	8	to	to	IN
cord-278081-tk7vn1v1	158	9	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	158	10	redistribution	redistribution	NN
cord-278081-tk7vn1v1	158	11	of	of	IN
cord-278081-tk7vn1v1	158	12	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	158	13	components	component	NNS
cord-278081-tk7vn1v1	158	14	to	to	IN
cord-278081-tk7vn1v1	158	15	the	the	DT
cord-278081-tk7vn1v1	158	16	nucleus	nucleus	NN
cord-278081-tk7vn1v1	158	17	,	,	,
cord-278081-tk7vn1v1	158	18	cytoplasm	cytoplasm	NN
cord-278081-tk7vn1v1	158	19	,	,	,
cord-278081-tk7vn1v1	158	20	and	and	CC
cord-278081-tk7vn1v1	158	21	even	even	RB
cord-278081-tk7vn1v1	158	22	cell	cell	NN
cord-278081-tk7vn1v1	158	23	surface	surface	NN
cord-278081-tk7vn1v1	158	24	(	(	-LRB-
cord-278081-tk7vn1v1	158	25	80	80	CD
cord-278081-tk7vn1v1	158	26	)	)	-RRB-
cord-278081-tk7vn1v1	158	27	.	.	.
cord-278081-tk7vn1v1	159	1	For	for	IN
cord-278081-tk7vn1v1	159	2	example	example	NN
cord-278081-tk7vn1v1	159	3	,	,	,
cord-278081-tk7vn1v1	159	4	viruses	virus	NNS
cord-278081-tk7vn1v1	159	5	induce	induce	VBP
cord-278081-tk7vn1v1	159	6	cell	cell	NN
cord-278081-tk7vn1v1	159	7	surface	surface	NN
cord-278081-tk7vn1v1	159	8	exposure	exposure	NN
cord-278081-tk7vn1v1	159	9	of	of	IN
cord-278081-tk7vn1v1	159	10	SSB	SSB	NNP
cord-278081-tk7vn1v1	159	11	/	/	SYM
cord-278081-tk7vn1v1	159	12	La	La	NNP
cord-278081-tk7vn1v1	159	13	which	which	WDT
cord-278081-tk7vn1v1	159	14	normally	normally	RB
cord-278081-tk7vn1v1	159	15	facilitates	facilitate	VBZ
cord-278081-tk7vn1v1	159	16	termination	termination	NN
cord-278081-tk7vn1v1	159	17	of	of	IN
cord-278081-tk7vn1v1	159	18	RNA	RNA	NNP
cord-278081-tk7vn1v1	159	19	pol	pol	NN
cord-278081-tk7vn1v1	159	20	III	III	NNP
cord-278081-tk7vn1v1	159	21	transcription	transcription	NN
cord-278081-tk7vn1v1	159	22	in	in	IN
cord-278081-tk7vn1v1	159	23	the	the	DT
cord-278081-tk7vn1v1	159	24	nucleus	nucleus	NN
cord-278081-tk7vn1v1	159	25	and	and	CC
cord-278081-tk7vn1v1	159	26	then	then	RB
cord-278081-tk7vn1v1	159	27	,	,	,
cord-278081-tk7vn1v1	159	28	along	along	IN
cord-278081-tk7vn1v1	159	29	with	with	IN
cord-278081-tk7vn1v1	159	30	SSA	SSA	NNP
cord-278081-tk7vn1v1	159	31	/	/	SYM
cord-278081-tk7vn1v1	159	32	Ro	Ro	NNP
cord-278081-tk7vn1v1	159	33	,	,	,
cord-278081-tk7vn1v1	159	34	acts	act	VBZ
cord-278081-tk7vn1v1	159	35	as	as	IN
cord-278081-tk7vn1v1	159	36	a	a	DT
cord-278081-tk7vn1v1	159	37	chaperone	chaperone	NN
cord-278081-tk7vn1v1	159	38	for	for	IN
cord-278081-tk7vn1v1	159	39	the	the	DT
cord-278081-tk7vn1v1	159	40	RNA	RNA	NNP
cord-278081-tk7vn1v1	159	41	transcript	transcript	NN
cord-278081-tk7vn1v1	159	42	as	as	IN
cord-278081-tk7vn1v1	159	43	it	-PRON-	PRP
cord-278081-tk7vn1v1	159	44	is	be	VBZ
cord-278081-tk7vn1v1	159	45	processed	process	VBN
cord-278081-tk7vn1v1	159	46	in	in	IN
cord-278081-tk7vn1v1	159	47	the	the	DT
cord-278081-tk7vn1v1	159	48	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	159	49	(	(	-LRB-
cord-278081-tk7vn1v1	159	50	81	81	CD
cord-278081-tk7vn1v1	159	51	)	)	-RRB-
cord-278081-tk7vn1v1	159	52	.	.	.
cord-278081-tk7vn1v1	160	1	Viruses	virus	NNS
cord-278081-tk7vn1v1	160	2	can	can	MD
cord-278081-tk7vn1v1	160	3	also	also	RB
cord-278081-tk7vn1v1	160	4	disrupt	disrupt	VB
cord-278081-tk7vn1v1	160	5	the	the	DT
cord-278081-tk7vn1v1	160	6	cell	cell	NN
cord-278081-tk7vn1v1	160	7	-	-	HYPH
cord-278081-tk7vn1v1	160	8	cycle	cycle	NN
cord-278081-tk7vn1v1	160	9	related	relate	VBN
cord-278081-tk7vn1v1	160	10	kinases	kinase	NNS
cord-278081-tk7vn1v1	160	11	in	in	IN
cord-278081-tk7vn1v1	160	12	the	the	DT
cord-278081-tk7vn1v1	160	13	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	160	14	,	,	,
cord-278081-tk7vn1v1	160	15	suppressing	suppress	VBG
cord-278081-tk7vn1v1	160	16	normal	normal	JJ
cord-278081-tk7vn1v1	160	17	cell	cell	NN
cord-278081-tk7vn1v1	160	18	cycling	cycling	NN
cord-278081-tk7vn1v1	160	19	and	and	CC
cord-278081-tk7vn1v1	160	20	,	,	,
cord-278081-tk7vn1v1	160	21	thereby	thereby	RB
cord-278081-tk7vn1v1	160	22	,	,	,
cord-278081-tk7vn1v1	160	23	hijacking	hijack	VBG
cord-278081-tk7vn1v1	160	24	the	the	DT
cord-278081-tk7vn1v1	160	25	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	160	26	to	to	TO
cord-278081-tk7vn1v1	160	27	focus	focus	VB
cord-278081-tk7vn1v1	160	28	on	on	IN
cord-278081-tk7vn1v1	160	29	viral	viral	JJ
cord-278081-tk7vn1v1	160	30	RNA	RNA	NNP
cord-278081-tk7vn1v1	160	31	and	and	CC
cord-278081-tk7vn1v1	160	32	protein	protein	NN
cord-278081-tk7vn1v1	160	33	synthesis	synthesis	NN
cord-278081-tk7vn1v1	160	34	and	and	CC
cord-278081-tk7vn1v1	160	35	assembly	assembly	NN
cord-278081-tk7vn1v1	160	36	of	of	IN
cord-278081-tk7vn1v1	160	37	viral	viral	JJ
cord-278081-tk7vn1v1	160	38	RNP	RNP	NNP
cord-278081-tk7vn1v1	160	39	complexes	complex	NNS
cord-278081-tk7vn1v1	160	40	(	(	-LRB-
cord-278081-tk7vn1v1	160	41	78	78	CD
cord-278081-tk7vn1v1	160	42	)	)	-RRB-
cord-278081-tk7vn1v1	160	43	.	.	.
cord-278081-tk7vn1v1	161	1	The	the	DT
cord-278081-tk7vn1v1	161	2	usual	usual	JJ
cord-278081-tk7vn1v1	161	3	effect	effect	NN
cord-278081-tk7vn1v1	161	4	of	of	IN
cord-278081-tk7vn1v1	161	5	cellular	cellular	JJ
cord-278081-tk7vn1v1	161	6	stress	stress	NN
cord-278081-tk7vn1v1	161	7	,	,	,
cord-278081-tk7vn1v1	161	8	such	such	JJ
cord-278081-tk7vn1v1	161	9	as	as	IN
cord-278081-tk7vn1v1	161	10	viral	viral	JJ
cord-278081-tk7vn1v1	161	11	activity	activity	NN
cord-278081-tk7vn1v1	161	12	,	,	,
cord-278081-tk7vn1v1	161	13	on	on	IN
cord-278081-tk7vn1v1	161	14	the	the	DT
cord-278081-tk7vn1v1	161	15	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	161	16	is	be	VBZ
cord-278081-tk7vn1v1	161	17	to	to	TO
cord-278081-tk7vn1v1	161	18	cause	cause	VB
cord-278081-tk7vn1v1	161	19	enlargement	enlargement	NN
cord-278081-tk7vn1v1	161	20	of	of	IN
cord-278081-tk7vn1v1	161	21	the	the	DT
cord-278081-tk7vn1v1	161	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	161	23	but	but	CC
cord-278081-tk7vn1v1	161	24	on	on	IN
cord-278081-tk7vn1v1	161	25	some	some	DT
cord-278081-tk7vn1v1	161	26	occasions	occasion	NNS
cord-278081-tk7vn1v1	161	27	the	the	DT
cord-278081-tk7vn1v1	161	28	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	161	29	can	can	MD
cord-278081-tk7vn1v1	161	30	actually	actually	RB
cord-278081-tk7vn1v1	161	31	decrease	decrease	VB
cord-278081-tk7vn1v1	161	32	in	in	IN
cord-278081-tk7vn1v1	161	33	size	size	NN
cord-278081-tk7vn1v1	161	34	.	.	.
cord-278081-tk7vn1v1	162	1	Inhibition	inhibition	NN
cord-278081-tk7vn1v1	162	2	of	of	IN
cord-278081-tk7vn1v1	162	3	RNA	RNA	NNP
cord-278081-tk7vn1v1	162	4	pol	pol	NN
cord-278081-tk7vn1v1	162	5	I	-PRON-	PRP
cord-278081-tk7vn1v1	162	6	by	by	IN
cord-278081-tk7vn1v1	162	7	poliovirus	poliovirus	NN
cord-278081-tk7vn1v1	162	8	,	,	,
cord-278081-tk7vn1v1	162	9	as	as	IN
cord-278081-tk7vn1v1	162	10	mentioned	mention	VBN
cord-278081-tk7vn1v1	162	11	above	above	RB
cord-278081-tk7vn1v1	162	12	,	,	,
cord-278081-tk7vn1v1	162	13	could	could	MD
cord-278081-tk7vn1v1	162	14	be	be	VB
cord-278081-tk7vn1v1	162	15	such	such	PDT
cord-278081-tk7vn1v1	162	16	a	a	DT
cord-278081-tk7vn1v1	162	17	situation	situation	NN
cord-278081-tk7vn1v1	162	18	since	since	IN
cord-278081-tk7vn1v1	162	19	a	a	DT
cord-278081-tk7vn1v1	162	20	drop	drop	NN
cord-278081-tk7vn1v1	162	21	in	in	IN
cord-278081-tk7vn1v1	162	22	rRNA	rrna	JJ
cord-278081-tk7vn1v1	162	23	transcripts	transcript	NNS
cord-278081-tk7vn1v1	162	24	would	would	MD
cord-278081-tk7vn1v1	162	25	inhibit	inhibit	VB
cord-278081-tk7vn1v1	162	26	the	the	DT
cord-278081-tk7vn1v1	162	27	major	major	JJ
cord-278081-tk7vn1v1	162	28	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	162	29	function	function	NN
cord-278081-tk7vn1v1	162	30	of	of	IN
cord-278081-tk7vn1v1	162	31	ribosome	ribosome	NN
cord-278081-tk7vn1v1	162	32	synthesis	synthesis	NN
cord-278081-tk7vn1v1	162	33	.	.	.
cord-278081-tk7vn1v1	163	1	tHe	the	DT
cord-278081-tk7vn1v1	164	1	"	"	``
cord-278081-tk7vn1v1	164	2	X	X	NNP
cord-278081-tk7vn1v1	164	3	CHroMosoMe	CHroMosoMe	NNP
cord-278081-tk7vn1v1	164	4	-	-	HYPH
cord-278081-tk7vn1v1	164	5	nUCLeoLUs	nUCLeoLUs	NNP
cord-278081-tk7vn1v1	164	6	neXUs	neXUs	NNP
cord-278081-tk7vn1v1	164	7	"	"	``
cord-278081-tk7vn1v1	164	8	HypotHesis	HypotHesis	NNP
cord-278081-tk7vn1v1	164	9	:	:	:
cord-278081-tk7vn1v1	164	10	disrUption	disruption	NN
cord-278081-tk7vn1v1	164	11	oF	of	IN
cord-278081-tk7vn1v1	164	12	tHe	the	DT
cord-278081-tk7vn1v1	165	1	inaCtiVe	inaCtiVe	NNP
cord-278081-tk7vn1v1	165	2	X	X	NNP
cord-278081-tk7vn1v1	165	3	The	the	DT
cord-278081-tk7vn1v1	165	4	stress	stress	NN
cord-278081-tk7vn1v1	165	5	that	that	IN
cord-278081-tk7vn1v1	165	6	viral	viral	JJ
cord-278081-tk7vn1v1	165	7	activity	activity	NN
cord-278081-tk7vn1v1	165	8	can	can	MD
cord-278081-tk7vn1v1	165	9	put	put	VB
cord-278081-tk7vn1v1	165	10	on	on	IN
cord-278081-tk7vn1v1	165	11	the	the	DT
cord-278081-tk7vn1v1	165	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	165	13	can	can	MD
cord-278081-tk7vn1v1	165	14	lead	lead	VB
cord-278081-tk7vn1v1	165	15	to	to	IN
cord-278081-tk7vn1v1	165	16	extensive	extensive	JJ
cord-278081-tk7vn1v1	165	17	enlargement	enlargement	NN
cord-278081-tk7vn1v1	165	18	of	of	IN
cord-278081-tk7vn1v1	165	19	the	the	DT
cord-278081-tk7vn1v1	165	20	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	165	21	.	.	.
cord-278081-tk7vn1v1	166	1	This	this	DT
cord-278081-tk7vn1v1	166	2	could	could	MD
cord-278081-tk7vn1v1	166	3	potentially	potentially	RB
cord-278081-tk7vn1v1	166	4	disrupt	disrupt	VB
cord-278081-tk7vn1v1	166	5	the	the	DT
cord-278081-tk7vn1v1	166	6	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	166	7	silencing	silencing	NN
cord-278081-tk7vn1v1	166	8	in	in	IN
cord-278081-tk7vn1v1	166	9	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	166	10	neighboring	neighbor	VBG
cord-278081-tk7vn1v1	166	11	the	the	DT
cord-278081-tk7vn1v1	166	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	166	13	.	.	.
cord-278081-tk7vn1v1	167	1	The	the	DT
cord-278081-tk7vn1v1	167	2	inactive	inactive	JJ
cord-278081-tk7vn1v1	167	3	X	x	NN
cord-278081-tk7vn1v1	167	4	chromosome	chromosome	NN
cord-278081-tk7vn1v1	167	5	,	,	,
cord-278081-tk7vn1v1	167	6	a.k.a	a.k.a	JJ
cord-278081-tk7vn1v1	167	7	.	.	.
cord-278081-tk7vn1v1	167	8	the	the	DT
cord-278081-tk7vn1v1	167	9	Barr	Barr	NNP
cord-278081-tk7vn1v1	167	10	body	body	NN
cord-278081-tk7vn1v1	167	11	,	,	,
cord-278081-tk7vn1v1	167	12	would	would	MD
cord-278081-tk7vn1v1	167	13	be	be	VB
cord-278081-tk7vn1v1	167	14	especially	especially	RB
cord-278081-tk7vn1v1	167	15	vulnerable	vulnerable	JJ
cord-278081-tk7vn1v1	167	16	,	,	,
cord-278081-tk7vn1v1	167	17	as	as	IN
cord-278081-tk7vn1v1	167	18	we	-PRON-	PRP
cord-278081-tk7vn1v1	167	19	proposed	propose	VBD
cord-278081-tk7vn1v1	167	20	in	in	IN
cord-278081-tk7vn1v1	167	21	the	the	DT
cord-278081-tk7vn1v1	167	22	original	original	JJ
cord-278081-tk7vn1v1	167	23	version	version	NN
cord-278081-tk7vn1v1	167	24	of	of	IN
cord-278081-tk7vn1v1	167	25	the	the	DT
cord-278081-tk7vn1v1	167	26	"	"	``
cord-278081-tk7vn1v1	167	27	X	x	NN
cord-278081-tk7vn1v1	167	28	chromosome	chromosome	NN
cord-278081-tk7vn1v1	167	29	-	-	HYPH
cord-278081-tk7vn1v1	167	30	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	167	31	nexus	nexus	NN
cord-278081-tk7vn1v1	167	32	"	"	''
cord-278081-tk7vn1v1	167	33	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	167	34	(	(	-LRB-
cord-278081-tk7vn1v1	167	35	1	1	CD
cord-278081-tk7vn1v1	167	36	)	)	-RRB-
cord-278081-tk7vn1v1	167	37	,	,	,
cord-278081-tk7vn1v1	167	38	since	since	IN
cord-278081-tk7vn1v1	167	39	the	the	DT
cord-278081-tk7vn1v1	167	40	Barr	Barr	NNP
cord-278081-tk7vn1v1	167	41	body	body	NN
cord-278081-tk7vn1v1	167	42	is	be	VBZ
cord-278081-tk7vn1v1	167	43	frequently	frequently	RB
cord-278081-tk7vn1v1	167	44	found	find	VBN
cord-278081-tk7vn1v1	167	45	in	in	IN
cord-278081-tk7vn1v1	167	46	close	close	JJ
cord-278081-tk7vn1v1	167	47	proximity	proximity	NN
cord-278081-tk7vn1v1	167	48	to	to	IN
cord-278081-tk7vn1v1	167	49	a	a	DT
cord-278081-tk7vn1v1	167	50	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	167	51	(	(	-LRB-
cord-278081-tk7vn1v1	167	52	57	57	CD
cord-278081-tk7vn1v1	167	53	)	)	-RRB-
cord-278081-tk7vn1v1	167	54	and	and	CC
cord-278081-tk7vn1v1	167	55	against	against	IN
cord-278081-tk7vn1v1	167	56	the	the	DT
cord-278081-tk7vn1v1	167	57	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	167	58	membrane	membrane	NN
cord-278081-tk7vn1v1	167	59	(	(	-LRB-
cord-278081-tk7vn1v1	167	60	82	82	CD
cord-278081-tk7vn1v1	167	61	)	)	-RRB-
cord-278081-tk7vn1v1	167	62	,	,	,
cord-278081-tk7vn1v1	167	63	as	as	IN
cord-278081-tk7vn1v1	167	64	depicted	depict	VBN
cord-278081-tk7vn1v1	167	65	in	in	IN
cord-278081-tk7vn1v1	167	66	Figure	figure	NN
cord-278081-tk7vn1v1	167	67	2A	2a	CD
cord-278081-tk7vn1v1	167	68	.	.	.
cord-278081-tk7vn1v1	168	1	Sandwiched	sandwich	VBN
cord-278081-tk7vn1v1	168	2	between	between	IN
cord-278081-tk7vn1v1	168	3	the	the	DT
cord-278081-tk7vn1v1	168	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	168	5	and	and	CC
cord-278081-tk7vn1v1	168	6	the	the	DT
cord-278081-tk7vn1v1	168	7	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	168	8	membrane	membrane	NN
cord-278081-tk7vn1v1	168	9	,	,	,
cord-278081-tk7vn1v1	168	10	the	the	DT
cord-278081-tk7vn1v1	168	11	Barr	Barr	NNP
cord-278081-tk7vn1v1	168	12	body	body	NN
cord-278081-tk7vn1v1	168	13	would	would	MD
cord-278081-tk7vn1v1	168	14	not	not	RB
cord-278081-tk7vn1v1	168	15	be	be	VB
cord-278081-tk7vn1v1	168	16	able	able	JJ
cord-278081-tk7vn1v1	168	17	to	to	TO
cord-278081-tk7vn1v1	168	18	avoid	avoid	VB
cord-278081-tk7vn1v1	168	19	exposure	exposure	NN
cord-278081-tk7vn1v1	168	20	and	and	CC
cord-278081-tk7vn1v1	168	21	disruption	disruption	NN
cord-278081-tk7vn1v1	168	22	due	due	IN
cord-278081-tk7vn1v1	168	23	to	to	IN
cord-278081-tk7vn1v1	168	24	the	the	DT
cord-278081-tk7vn1v1	168	25	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	168	26	and	and	CC
cord-278081-tk7vn1v1	168	27	nucleophosmin	nucleophosmin	NNS
cord-278081-tk7vn1v1	168	28	that	that	WDT
cord-278081-tk7vn1v1	168	29	are	be	VBP
cord-278081-tk7vn1v1	168	30	involved	involve	VBN
cord-278081-tk7vn1v1	168	31	in	in	IN
cord-278081-tk7vn1v1	168	32	chromatin	chromatin	NN
cord-278081-tk7vn1v1	168	33	remodeling	remodeling	NN
cord-278081-tk7vn1v1	168	34	from	from	IN
cord-278081-tk7vn1v1	168	35	an	an	DT
cord-278081-tk7vn1v1	168	36	expanding	expand	VBG
cord-278081-tk7vn1v1	168	37	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	168	38	(	(	-LRB-
cord-278081-tk7vn1v1	168	39	83	83	CD
cord-278081-tk7vn1v1	168	40	,	,	,
cord-278081-tk7vn1v1	168	41	84	84	CD
cord-278081-tk7vn1v1	168	42	)	)	-RRB-
cord-278081-tk7vn1v1	168	43	.	.	.
cord-278081-tk7vn1v1	169	1	In	in	IN
cord-278081-tk7vn1v1	169	2	addition	addition	NN
cord-278081-tk7vn1v1	169	3	,	,	,
cord-278081-tk7vn1v1	169	4	exposure	exposure	NN
cord-278081-tk7vn1v1	169	5	of	of	IN
cord-278081-tk7vn1v1	169	6	the	the	DT
cord-278081-tk7vn1v1	169	7	chromatin	chromatin	NN
cord-278081-tk7vn1v1	169	8	to	to	IN
cord-278081-tk7vn1v1	169	9	the	the	DT
cord-278081-tk7vn1v1	169	10	high	high	JJ
cord-278081-tk7vn1v1	169	11	content	content	NN
cord-278081-tk7vn1v1	169	12	of	of	IN
cord-278081-tk7vn1v1	169	13	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	169	14	in	in	IN
cord-278081-tk7vn1v1	169	15	the	the	DT
cord-278081-tk7vn1v1	169	16	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	169	17	could	could	MD
cord-278081-tk7vn1v1	169	18	add	add	VB
cord-278081-tk7vn1v1	169	19	to	to	IN
cord-278081-tk7vn1v1	169	20	the	the	DT
cord-278081-tk7vn1v1	169	21	disruption	disruption	NN
cord-278081-tk7vn1v1	169	22	of	of	IN
cord-278081-tk7vn1v1	169	23	chromatin	chromatin	NN
cord-278081-tk7vn1v1	169	24	since	since	IN
cord-278081-tk7vn1v1	169	25	the	the	DT
cord-278081-tk7vn1v1	169	26	cationic	cationic	JJ
cord-278081-tk7vn1v1	169	27	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	169	28	can	can	MD
cord-278081-tk7vn1v1	169	29	compete	compete	VB
cord-278081-tk7vn1v1	169	30	with	with	IN
cord-278081-tk7vn1v1	169	31	histones	histone	NNS
cord-278081-tk7vn1v1	169	32	for	for	IN
cord-278081-tk7vn1v1	169	33	DNA	dna	NN
cord-278081-tk7vn1v1	169	34	binding	binding	NN
cord-278081-tk7vn1v1	169	35	.	.	.
cord-278081-tk7vn1v1	170	1	Moreover	moreover	RB
cord-278081-tk7vn1v1	170	2	,	,	,
cord-278081-tk7vn1v1	170	3	the	the	DT
cord-278081-tk7vn1v1	170	4	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	170	5	have	have	VBP
cord-278081-tk7vn1v1	170	6	the	the	DT
cord-278081-tk7vn1v1	170	7	potential	potential	NN
cord-278081-tk7vn1v1	170	8	to	to	TO
cord-278081-tk7vn1v1	170	9	stabilize	stabilize	VB
cord-278081-tk7vn1v1	170	10	alternate	alternate	JJ
cord-278081-tk7vn1v1	170	11	DNA	dna	NN
cord-278081-tk7vn1v1	170	12	conformations	conformation	NNS
cord-278081-tk7vn1v1	170	13	,	,	,
cord-278081-tk7vn1v1	170	14	such	such	JJ
cord-278081-tk7vn1v1	170	15	as	as	IN
cord-278081-tk7vn1v1	170	16	Z	z	NN
cord-278081-tk7vn1v1	170	17	-	-	HYPH
cord-278081-tk7vn1v1	170	18	DNA	dna	NN
cord-278081-tk7vn1v1	170	19	,	,	,
cord-278081-tk7vn1v1	170	20	which	which	WDT
cord-278081-tk7vn1v1	170	21	is	be	VBZ
cord-278081-tk7vn1v1	170	22	targeted	target	VBN
cord-278081-tk7vn1v1	170	23	by	by	IN
cord-278081-tk7vn1v1	170	24	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	170	25	in	in	IN
cord-278081-tk7vn1v1	170	26	some	some	DT
cord-278081-tk7vn1v1	170	27	cases	case	NNS
cord-278081-tk7vn1v1	170	28	of	of	IN
cord-278081-tk7vn1v1	170	29	SLE	SLE	NNP
cord-278081-tk7vn1v1	170	30	and	and	CC
cord-278081-tk7vn1v1	170	31	RA	RA	NNP
cord-278081-tk7vn1v1	170	32	.	.	.
cord-278081-tk7vn1v1	171	1	Negative	negative	JJ
cord-278081-tk7vn1v1	171	2	supercoiling	supercoile	VBG
cord-278081-tk7vn1v1	171	3	stress	stress	NN
cord-278081-tk7vn1v1	171	4	is	be	VBZ
cord-278081-tk7vn1v1	171	5	stored	store	VBN
cord-278081-tk7vn1v1	171	6	in	in	IN
cord-278081-tk7vn1v1	171	7	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	171	8	as	as	IN
cord-278081-tk7vn1v1	171	9	the	the	DT
cord-278081-tk7vn1v1	171	10	double	double	RB
cord-278081-tk7vn1v1	171	11	-	-	HYPH
cord-278081-tk7vn1v1	171	12	stranded	strand	VBN
cord-278081-tk7vn1v1	171	13	right	right	JJ
cord-278081-tk7vn1v1	171	14	-	-	HYPH
cord-278081-tk7vn1v1	171	15	hand	hand	NN
cord-278081-tk7vn1v1	171	16	coiled	coiled	JJ
cord-278081-tk7vn1v1	171	17	B	b	NN
cord-278081-tk7vn1v1	171	18	-	-	HYPH
cord-278081-tk7vn1v1	171	19	DNA	DNA	NNP
cord-278081-tk7vn1v1	171	20	makes	make	VBZ
cord-278081-tk7vn1v1	171	21	a	a	DT
cord-278081-tk7vn1v1	171	22	left	left	JJ
cord-278081-tk7vn1v1	171	23	-	-	HYPH
cord-278081-tk7vn1v1	171	24	handed	handed	JJ
cord-278081-tk7vn1v1	171	25	supercoil	supercoil	NN
cord-278081-tk7vn1v1	171	26	over	over	IN
cord-278081-tk7vn1v1	171	27	the	the	DT
cord-278081-tk7vn1v1	171	28	surface	surface	NN
cord-278081-tk7vn1v1	171	29	of	of	IN
cord-278081-tk7vn1v1	171	30	the	the	DT
cord-278081-tk7vn1v1	171	31	nucleosome	nucleosome	NN
cord-278081-tk7vn1v1	171	32	's	's	POS
cord-278081-tk7vn1v1	171	33	histones	histone	NNS
cord-278081-tk7vn1v1	171	34	.	.	.
cord-278081-tk7vn1v1	172	1	Displacement	displacement	NN
cord-278081-tk7vn1v1	172	2	of	of	IN
cord-278081-tk7vn1v1	172	3	the	the	DT
cord-278081-tk7vn1v1	172	4	histones	histone	NNS
cord-278081-tk7vn1v1	172	5	during	during	IN
cord-278081-tk7vn1v1	172	6	chromatin	chromatin	NN
cord-278081-tk7vn1v1	172	7	remodeling	remodeling	NN
cord-278081-tk7vn1v1	172	8	could	could	MD
cord-278081-tk7vn1v1	172	9	release	release	VB
cord-278081-tk7vn1v1	172	10	the	the	DT
cord-278081-tk7vn1v1	172	11	negative	negative	JJ
cord-278081-tk7vn1v1	172	12	supercoiling	supercoiling	NN
cord-278081-tk7vn1v1	172	13	stress	stress	NN
cord-278081-tk7vn1v1	172	14	,	,	,
cord-278081-tk7vn1v1	172	15	allowing	allow	VBG
cord-278081-tk7vn1v1	172	16	it	-PRON-	PRP
cord-278081-tk7vn1v1	172	17	to	to	TO
cord-278081-tk7vn1v1	172	18	flux	flux	VB
cord-278081-tk7vn1v1	172	19	through	through	IN
cord-278081-tk7vn1v1	172	20	the	the	DT
cord-278081-tk7vn1v1	172	21	DNA	dna	NN
cord-278081-tk7vn1v1	172	22	and	and	CC
cord-278081-tk7vn1v1	172	23	potentially	potentially	RB
cord-278081-tk7vn1v1	172	24	flipping	flip	VBG
cord-278081-tk7vn1v1	172	25	into	into	IN
cord-278081-tk7vn1v1	172	26	left	left	JJ
cord-278081-tk7vn1v1	172	27	-	-	HYPH
cord-278081-tk7vn1v1	172	28	hand	hand	NN
cord-278081-tk7vn1v1	172	29	coiled	coil	VBN
cord-278081-tk7vn1v1	172	30	Z	z	NN
cord-278081-tk7vn1v1	172	31	-	-	HYPH
cord-278081-tk7vn1v1	172	32	DNA	DNA	NNP
cord-278081-tk7vn1v1	172	33	which	which	WDT
cord-278081-tk7vn1v1	172	34	is	be	VBZ
cord-278081-tk7vn1v1	172	35	also	also	RB
cord-278081-tk7vn1v1	172	36	a	a	DT
cord-278081-tk7vn1v1	172	37	form	form	NN
cord-278081-tk7vn1v1	172	38	of	of	IN
cord-278081-tk7vn1v1	172	39	negative	negative	JJ
cord-278081-tk7vn1v1	172	40	supercoiling	supercoiling	NN
cord-278081-tk7vn1v1	172	41	storage	storage	NN
cord-278081-tk7vn1v1	172	42	.	.	.
cord-278081-tk7vn1v1	173	1	Z	Z	NNP
cord-278081-tk7vn1v1	173	2	-	-	HYPH
cord-278081-tk7vn1v1	173	3	DNA	DNA	NNP
cord-278081-tk7vn1v1	173	4	appears	appear	VBZ
cord-278081-tk7vn1v1	173	5	only	only	RB
cord-278081-tk7vn1v1	173	6	transiently	transiently	RB
cord-278081-tk7vn1v1	173	7	in	in	IN
cord-278081-tk7vn1v1	173	8	chromatin	chromatin	NN
cord-278081-tk7vn1v1	173	9	since	since	IN
cord-278081-tk7vn1v1	173	10	most	most	JJS
cord-278081-tk7vn1v1	173	11	DNA	DNA	NNP
cord-278081-tk7vn1v1	173	12	is	be	VBZ
cord-278081-tk7vn1v1	173	13	wrapped	wrap	VBN
cord-278081-tk7vn1v1	173	14	up	up	RP
cord-278081-tk7vn1v1	173	15	as	as	IN
cord-278081-tk7vn1v1	173	16	B	b	NN
cord-278081-tk7vn1v1	173	17	-	-	HYPH
cord-278081-tk7vn1v1	173	18	DNA	dna	NN
cord-278081-tk7vn1v1	173	19	in	in	RP
cord-278081-tk7vn1v1	173	20	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	173	21	.	.	.
cord-278081-tk7vn1v1	174	1	Z	z	NN
cord-278081-tk7vn1v1	174	2	-	-	HYPH
cord-278081-tk7vn1v1	174	3	DNA	DNA	NNP
cord-278081-tk7vn1v1	174	4	is	be	VBZ
cord-278081-tk7vn1v1	174	5	not	not	RB
cord-278081-tk7vn1v1	174	6	flexible	flexible	JJ
cord-278081-tk7vn1v1	174	7	enough	enough	RB
cord-278081-tk7vn1v1	174	8	to	to	TO
cord-278081-tk7vn1v1	174	9	bend	bend	VB
cord-278081-tk7vn1v1	174	10	around	around	RB
cord-278081-tk7vn1v1	174	11	histones	histone	NNS
cord-278081-tk7vn1v1	174	12	so	so	IN
cord-278081-tk7vn1v1	174	13	it	-PRON-	PRP
cord-278081-tk7vn1v1	174	14	is	be	VBZ
cord-278081-tk7vn1v1	174	15	excluded	exclude	VBN
cord-278081-tk7vn1v1	174	16	from	from	IN
cord-278081-tk7vn1v1	174	17	the	the	DT
cord-278081-tk7vn1v1	174	18	145	145	CD
cord-278081-tk7vn1v1	174	19	bp	bp	NNS
cord-278081-tk7vn1v1	174	20	bound	bind	VBN
cord-278081-tk7vn1v1	174	21	to	to	IN
cord-278081-tk7vn1v1	174	22	the	the	DT
cord-278081-tk7vn1v1	174	23	surface	surface	NN
cord-278081-tk7vn1v1	174	24	of	of	IN
cord-278081-tk7vn1v1	174	25	the	the	DT
cord-278081-tk7vn1v1	174	26	histones	histone	NNS
cord-278081-tk7vn1v1	174	27	.	.	.
cord-278081-tk7vn1v1	175	1	Since	since	IN
cord-278081-tk7vn1v1	175	2	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	175	3	in	in	IN
cord-278081-tk7vn1v1	175	4	human	human	JJ
cord-278081-tk7vn1v1	175	5	chromatin	chromatin	NN
cord-278081-tk7vn1v1	175	6	occur	occur	VBP
cord-278081-tk7vn1v1	175	7	every	every	DT
cord-278081-tk7vn1v1	175	8	200	200	CD
cord-278081-tk7vn1v1	175	9	bp	bp	NNP
cord-278081-tk7vn1v1	175	10	on	on	IN
cord-278081-tk7vn1v1	175	11	average	average	JJ
cord-278081-tk7vn1v1	175	12	,	,	,
cord-278081-tk7vn1v1	175	13	there	there	EX
cord-278081-tk7vn1v1	175	14	is	be	VBZ
cord-278081-tk7vn1v1	175	15	normally	normally	RB
cord-278081-tk7vn1v1	175	16	little	little	JJ
cord-278081-tk7vn1v1	175	17	opportunity	opportunity	NN
cord-278081-tk7vn1v1	175	18	for	for	IN
cord-278081-tk7vn1v1	175	19	Z	z	NN
cord-278081-tk7vn1v1	175	20	-	-	HYPH
cord-278081-tk7vn1v1	175	21	DNA	dna	NN
cord-278081-tk7vn1v1	175	22	to	to	TO
cord-278081-tk7vn1v1	175	23	form	form	VB
cord-278081-tk7vn1v1	175	24	and	and	CC
cord-278081-tk7vn1v1	175	25	persist	persist	VB
cord-278081-tk7vn1v1	175	26	.	.	.
cord-278081-tk7vn1v1	176	1	Exposure	exposure	NN
cord-278081-tk7vn1v1	176	2	to	to	IN
cord-278081-tk7vn1v1	176	3	high	high	JJ
cord-278081-tk7vn1v1	176	4	levels	level	NNS
cord-278081-tk7vn1v1	176	5	of	of	IN
cord-278081-tk7vn1v1	176	6	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	176	7	from	from	IN
cord-278081-tk7vn1v1	176	8	the	the	DT
cord-278081-tk7vn1v1	176	9	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	176	10	concomitant	concomitant	JJ
cord-278081-tk7vn1v1	176	11	with	with	IN
cord-278081-tk7vn1v1	176	12	disruption	disruption	NN
cord-278081-tk7vn1v1	176	13	of	of	IN
cord-278081-tk7vn1v1	176	14	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	176	15	could	could	MD
cord-278081-tk7vn1v1	176	16	increase	increase	VB
cord-278081-tk7vn1v1	176	17	the	the	DT
cord-278081-tk7vn1v1	176	18	likelihood	likelihood	NN
cord-278081-tk7vn1v1	176	19	of	of	IN
cord-278081-tk7vn1v1	176	20	Z	z	NN
cord-278081-tk7vn1v1	176	21	-	-	HYPH
cord-278081-tk7vn1v1	176	22	DNA	dna	NN
cord-278081-tk7vn1v1	176	23	persistence	persistence	NN
cord-278081-tk7vn1v1	176	24	when	when	WRB
cord-278081-tk7vn1v1	176	25	there	there	EX
cord-278081-tk7vn1v1	176	26	is	be	VBZ
cord-278081-tk7vn1v1	176	27	a	a	DT
cord-278081-tk7vn1v1	176	28	shift	shift	NN
cord-278081-tk7vn1v1	176	29	of	of	IN
cord-278081-tk7vn1v1	176	30	negative	negative	JJ
cord-278081-tk7vn1v1	176	31	supercoiling	supercoiling	NN
cord-278081-tk7vn1v1	176	32	storage	storage	NN
cord-278081-tk7vn1v1	176	33	from	from	IN
cord-278081-tk7vn1v1	176	34	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	176	35	to	to	IN
cord-278081-tk7vn1v1	176	36	Z	z	NN
cord-278081-tk7vn1v1	176	37	-	-	HYPH
cord-278081-tk7vn1v1	176	38	DNA	dna	NN
cord-278081-tk7vn1v1	176	39	(	(	-LRB-
cord-278081-tk7vn1v1	176	40	85	85	CD
cord-278081-tk7vn1v1	176	41	)	)	-RRB-
cord-278081-tk7vn1v1	176	42	.	.	.
cord-278081-tk7vn1v1	177	1	In	in	IN
cord-278081-tk7vn1v1	177	2	a	a	DT
cord-278081-tk7vn1v1	177	3	similar	similar	JJ
cord-278081-tk7vn1v1	177	4	manner	manner	NN
cord-278081-tk7vn1v1	177	5	,	,	,
cord-278081-tk7vn1v1	177	6	DNA	dna	NN
cord-278081-tk7vn1v1	177	7	cruciforms	cruciform	NNS
cord-278081-tk7vn1v1	177	8	are	be	VBP
cord-278081-tk7vn1v1	177	9	formed	form	VBN
cord-278081-tk7vn1v1	177	10	from	from	IN
cord-278081-tk7vn1v1	177	11	negative	negative	JJ
cord-278081-tk7vn1v1	177	12	supercoiling	supercoile	VBG
cord-278081-tk7vn1v1	177	13	stress	stress	NN
cord-278081-tk7vn1v1	177	14	but	but	CC
cord-278081-tk7vn1v1	177	15	their	-PRON-	PRP$
cord-278081-tk7vn1v1	177	16	occurrence	occurrence	NN
cord-278081-tk7vn1v1	177	17	is	be	VBZ
cord-278081-tk7vn1v1	177	18	also	also	RB
cord-278081-tk7vn1v1	177	19	suppressed	suppress	VBN
cord-278081-tk7vn1v1	177	20	by	by	IN
cord-278081-tk7vn1v1	177	21	positioned	position	VBN
cord-278081-tk7vn1v1	177	22	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	177	23	.	.	.
cord-278081-tk7vn1v1	178	1	The	the	DT
cord-278081-tk7vn1v1	178	2	Alu	Alu	NNP
cord-278081-tk7vn1v1	178	3	elements	element	NNS
cord-278081-tk7vn1v1	178	4	,	,	,
cord-278081-tk7vn1v1	178	5	of	of	IN
cord-278081-tk7vn1v1	178	6	which	which	WDT
cord-278081-tk7vn1v1	178	7	there	there	EX
cord-278081-tk7vn1v1	178	8	are	be	VBP
cord-278081-tk7vn1v1	178	9	more	more	JJR
cord-278081-tk7vn1v1	178	10	than	than	IN
cord-278081-tk7vn1v1	178	11	one	one	CD
cord-278081-tk7vn1v1	178	12	million	million	CD
cord-278081-tk7vn1v1	178	13	throughout	throughout	IN
cord-278081-tk7vn1v1	178	14	the	the	DT
cord-278081-tk7vn1v1	178	15	human	human	JJ
cord-278081-tk7vn1v1	178	16	genome	genome	NN
cord-278081-tk7vn1v1	178	17	,	,	,
cord-278081-tk7vn1v1	178	18	contain	contain	VBP
cord-278081-tk7vn1v1	178	19	sequences	sequence	NNS
cord-278081-tk7vn1v1	178	20	capable	capable	JJ
cord-278081-tk7vn1v1	178	21	of	of	IN
cord-278081-tk7vn1v1	178	22	cruciform	cruciform	JJ
cord-278081-tk7vn1v1	178	23	formation	formation	NN
cord-278081-tk7vn1v1	178	24	(	(	-LRB-
cord-278081-tk7vn1v1	178	25	1	1	CD
cord-278081-tk7vn1v1	178	26	)	)	-RRB-
cord-278081-tk7vn1v1	178	27	.	.	.
cord-278081-tk7vn1v1	179	1	Since	since	IN
cord-278081-tk7vn1v1	179	2	there	there	EX
cord-278081-tk7vn1v1	179	3	are	be	VBP
cord-278081-tk7vn1v1	179	4	approximately	approximately	RB
cord-278081-tk7vn1v1	179	5	15	15	CD
cord-278081-tk7vn1v1	179	6	million	million	CD
cord-278081-tk7vn1v1	179	7	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	179	8	associated	associate	VBN
cord-278081-tk7vn1v1	179	9	with	with	IN
cord-278081-tk7vn1v1	179	10	the	the	DT
cord-278081-tk7vn1v1	179	11	human	human	JJ
cord-278081-tk7vn1v1	179	12	genomic	genomic	JJ
cord-278081-tk7vn1v1	179	13	DNA	dna	NN
cord-278081-tk7vn1v1	179	14	,	,	,
cord-278081-tk7vn1v1	179	15	there	there	EX
cord-278081-tk7vn1v1	179	16	is	be	VBZ
cord-278081-tk7vn1v1	179	17	ample	ample	JJ
cord-278081-tk7vn1v1	179	18	stored	store	VBN
cord-278081-tk7vn1v1	179	19	negative	negative	JJ
cord-278081-tk7vn1v1	179	20	supercoiling	supercoiling	NN
cord-278081-tk7vn1v1	179	21	stress	stress	NN
cord-278081-tk7vn1v1	179	22	.	.	.
cord-278081-tk7vn1v1	180	1	This	this	DT
cord-278081-tk7vn1v1	180	2	potential	potential	NN
cord-278081-tk7vn1v1	180	3	for	for	IN
cord-278081-tk7vn1v1	180	4	rapid	rapid	JJ
cord-278081-tk7vn1v1	180	5	dynamic	dynamic	JJ
cord-278081-tk7vn1v1	180	6	changes	change	NNS
cord-278081-tk7vn1v1	180	7	in	in	IN
cord-278081-tk7vn1v1	180	8	chromatin	chromatin	NN
cord-278081-tk7vn1v1	180	9	,	,	,
cord-278081-tk7vn1v1	180	10	including	include	VBG
cord-278081-tk7vn1v1	180	11	disruption	disruption	NN
cord-278081-tk7vn1v1	180	12	of	of	IN
cord-278081-tk7vn1v1	180	13	higher	high	JJR
cord-278081-tk7vn1v1	180	14	order	order	NN
cord-278081-tk7vn1v1	180	15	"	"	``
cord-278081-tk7vn1v1	180	16	stacked	stack	VBN
cord-278081-tk7vn1v1	180	17	"	"	''
cord-278081-tk7vn1v1	180	18	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	180	19	,	,	,
cord-278081-tk7vn1v1	180	20	alternate	alternate	JJ
cord-278081-tk7vn1v1	180	21	DNA	dna	NN
cord-278081-tk7vn1v1	180	22	conformations	conformation	NNS
cord-278081-tk7vn1v1	180	23	,	,	,
cord-278081-tk7vn1v1	180	24	displacement	displacement	NN
cord-278081-tk7vn1v1	180	25	of	of	IN
cord-278081-tk7vn1v1	180	26	bound	bind	VBN
cord-278081-tk7vn1v1	180	27	proteins	protein	NNS
cord-278081-tk7vn1v1	180	28	,	,	,
cord-278081-tk7vn1v1	180	29	and	and	CC
cord-278081-tk7vn1v1	180	30	DNA	dna	NN
cord-278081-tk7vn1v1	180	31	strand	strand	NN
cord-278081-tk7vn1v1	180	32	separation	separation	NN
cord-278081-tk7vn1v1	180	33	,	,	,
cord-278081-tk7vn1v1	180	34	is	be	VBZ
cord-278081-tk7vn1v1	180	35	perhaps	perhaps	RB
cord-278081-tk7vn1v1	180	36	FiGUre	FiGUre	NNP
cord-278081-tk7vn1v1	180	37	3	3	CD
cord-278081-tk7vn1v1	180	38	|	|	NNP
cord-278081-tk7vn1v1	180	39	Establishment	Establishment	NNP
cord-278081-tk7vn1v1	180	40	of	of	IN
cord-278081-tk7vn1v1	180	41	the	the	DT
cord-278081-tk7vn1v1	180	42	inactive	inactive	JJ
cord-278081-tk7vn1v1	180	43	X	x	NN
cord-278081-tk7vn1v1	180	44	chromosome	chromosome	NN
cord-278081-tk7vn1v1	180	45	(	(	-LRB-
cord-278081-tk7vn1v1	180	46	Xi	Xi	NNP
cord-278081-tk7vn1v1	180	47	)	)	-RRB-
cord-278081-tk7vn1v1	180	48	.	.	.
cord-278081-tk7vn1v1	181	1	Early	early	RB
cord-278081-tk7vn1v1	181	2	in	in	IN
cord-278081-tk7vn1v1	181	3	embryogenesis	embryogenesis	NN
cord-278081-tk7vn1v1	181	4	one	one	CD
cord-278081-tk7vn1v1	181	5	of	of	IN
cord-278081-tk7vn1v1	181	6	the	the	DT
cord-278081-tk7vn1v1	181	7	two	two	CD
cord-278081-tk7vn1v1	181	8	X	x	NN
cord-278081-tk7vn1v1	181	9	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	181	10	in	in	IN
cord-278081-tk7vn1v1	181	11	female	female	JJ
cord-278081-tk7vn1v1	181	12	cells	cell	NNS
cord-278081-tk7vn1v1	181	13	is	be	VBZ
cord-278081-tk7vn1v1	181	14	inactivated	inactivate	VBN
cord-278081-tk7vn1v1	181	15	by	by	IN
cord-278081-tk7vn1v1	181	16	persistent	persistent	JJ
cord-278081-tk7vn1v1	181	17	expression	expression	NN
cord-278081-tk7vn1v1	181	18	of	of	IN
cord-278081-tk7vn1v1	181	19	the	the	DT
cord-278081-tk7vn1v1	181	20	X	x	NN
cord-278081-tk7vn1v1	181	21	inactivation	inactivation	NN
cord-278081-tk7vn1v1	181	22	specific	specific	JJ
cord-278081-tk7vn1v1	181	23	transcript	transcript	NN
cord-278081-tk7vn1v1	181	24	RNA	RNA	NNP
cord-278081-tk7vn1v1	181	25	(	(	-LRB-
cord-278081-tk7vn1v1	181	26	XIST	XIST	NNP
cord-278081-tk7vn1v1	181	27	)	)	-RRB-
cord-278081-tk7vn1v1	181	28	from	from	IN
cord-278081-tk7vn1v1	181	29	the	the	DT
cord-278081-tk7vn1v1	181	30	X	x	NN
cord-278081-tk7vn1v1	181	31	inactivation	inactivation	NN
cord-278081-tk7vn1v1	181	32	center	center	NN
cord-278081-tk7vn1v1	181	33	(	(	-LRB-
cord-278081-tk7vn1v1	181	34	XIC	XIC	NNP
cord-278081-tk7vn1v1	181	35	)	)	-RRB-
cord-278081-tk7vn1v1	181	36	.	.	.
cord-278081-tk7vn1v1	182	1	XIST	XIST	NNP
cord-278081-tk7vn1v1	182	2	RNA	RNA	NNP
cord-278081-tk7vn1v1	182	3	does	do	VBZ
cord-278081-tk7vn1v1	182	4	not	not	RB
cord-278081-tk7vn1v1	182	5	code	code	VB
cord-278081-tk7vn1v1	182	6	for	for	IN
cord-278081-tk7vn1v1	182	7	protein	protein	NN
cord-278081-tk7vn1v1	182	8	but	but	CC
cord-278081-tk7vn1v1	182	9	remains	remain	VBZ
cord-278081-tk7vn1v1	182	10	in	in	IN
cord-278081-tk7vn1v1	182	11	the	the	DT
cord-278081-tk7vn1v1	182	12	nucleus	nucleus	NN
cord-278081-tk7vn1v1	182	13	and	and	CC
cord-278081-tk7vn1v1	182	14	binds	bind	VBZ
cord-278081-tk7vn1v1	182	15	contiguous	contiguous	JJ
cord-278081-tk7vn1v1	182	16	chromatin	chromatin	NN
cord-278081-tk7vn1v1	182	17	(	(	-LRB-
cord-278081-tk7vn1v1	182	18	i.e.	i.e.	FW
cord-278081-tk7vn1v1	182	19	,	,	,
cord-278081-tk7vn1v1	182	20	the	the	DT
cord-278081-tk7vn1v1	182	21	Xi	Xi	NNP
cord-278081-tk7vn1v1	182	22	,	,	,
cord-278081-tk7vn1v1	182	23	a.k.a	a.k.a	JJ
cord-278081-tk7vn1v1	182	24	.	.	.
cord-278081-tk7vn1v1	182	25	the	the	DT
cord-278081-tk7vn1v1	182	26	Barr	Barr	NNP
cord-278081-tk7vn1v1	182	27	body	body	NN
cord-278081-tk7vn1v1	182	28	)	)	-RRB-
cord-278081-tk7vn1v1	182	29	,	,	,
cord-278081-tk7vn1v1	182	30	recruiting	recruit	VBG
cord-278081-tk7vn1v1	182	31	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	182	32	silencing	silencing	NN
cord-278081-tk7vn1v1	182	33	effectors	effector	NNS
cord-278081-tk7vn1v1	182	34	(	(	-LRB-
cord-278081-tk7vn1v1	182	35	e.g.	e.g.	RB
cord-278081-tk7vn1v1	182	36	,	,	,
cord-278081-tk7vn1v1	182	37	DNA	dna	NN
cord-278081-tk7vn1v1	182	38	methyltransferases	methyltransferase	NNS
cord-278081-tk7vn1v1	182	39	)	)	-RRB-
cord-278081-tk7vn1v1	182	40	.	.	.
cord-278081-tk7vn1v1	183	1	Approximately	approximately	RB
cord-278081-tk7vn1v1	183	2	95	95	CD
cord-278081-tk7vn1v1	183	3	%	%	NN
cord-278081-tk7vn1v1	183	4	of	of	IN
cord-278081-tk7vn1v1	183	5	genes	gene	NNS
cord-278081-tk7vn1v1	183	6	from	from	IN
cord-278081-tk7vn1v1	183	7	the	the	DT
cord-278081-tk7vn1v1	183	8	long	long	JJ
cord-278081-tk7vn1v1	183	9	arm	arm	NN
cord-278081-tk7vn1v1	183	10	(	(	-LRB-
cord-278081-tk7vn1v1	183	11	Xq	Xq	NNP
cord-278081-tk7vn1v1	183	12	)	)	-RRB-
cord-278081-tk7vn1v1	183	13	and	and	CC
cord-278081-tk7vn1v1	183	14	65	65	CD
cord-278081-tk7vn1v1	183	15	%	%	NN
cord-278081-tk7vn1v1	183	16	of	of	IN
cord-278081-tk7vn1v1	183	17	genes	gene	NNS
cord-278081-tk7vn1v1	183	18	from	from	IN
cord-278081-tk7vn1v1	183	19	the	the	DT
cord-278081-tk7vn1v1	183	20	short	short	JJ
cord-278081-tk7vn1v1	183	21	arm	arm	NN
cord-278081-tk7vn1v1	183	22	(	(	-LRB-
cord-278081-tk7vn1v1	183	23	Xp	Xp	NNP
cord-278081-tk7vn1v1	183	24	)	)	-RRB-
cord-278081-tk7vn1v1	183	25	are	be	VBP
cord-278081-tk7vn1v1	183	26	silenced	silence	VBN
cord-278081-tk7vn1v1	183	27	.	.	.
cord-278081-tk7vn1v1	184	1	Silenced	silenced	JJ
cord-278081-tk7vn1v1	184	2	genes	gene	NNS
cord-278081-tk7vn1v1	184	3	shown	show	VBN
cord-278081-tk7vn1v1	184	4	as	as	IN
cord-278081-tk7vn1v1	184	5	dark	dark	JJ
cord-278081-tk7vn1v1	184	6	blue	blue	NN
cord-278081-tk7vn1v1	184	7	,	,	,
cord-278081-tk7vn1v1	184	8	while	while	IN
cord-278081-tk7vn1v1	184	9	genes	gene	NNS
cord-278081-tk7vn1v1	184	10	that	that	WDT
cord-278081-tk7vn1v1	184	11	escape	escape	VBP
cord-278081-tk7vn1v1	184	12	inactivation	inactivation	NN
cord-278081-tk7vn1v1	184	13	are	be	VBP
cord-278081-tk7vn1v1	184	14	shown	show	VBN
cord-278081-tk7vn1v1	184	15	as	as	IN
cord-278081-tk7vn1v1	184	16	light	light	JJ
cord-278081-tk7vn1v1	184	17	blue	blue	JJ
cord-278081-tk7vn1v1	184	18	[	[	-LRB-
cord-278081-tk7vn1v1	184	19	based	base	VBN
cord-278081-tk7vn1v1	184	20	on	on	IN
cord-278081-tk7vn1v1	184	21	Ref	Ref	NNP
cord-278081-tk7vn1v1	184	22	.	.	.
cord-278081-tk7vn1v1	185	1	(	(	-LRB-
cord-278081-tk7vn1v1	185	2	89	89	CD
cord-278081-tk7vn1v1	185	3	)	)	-RRB-
cord-278081-tk7vn1v1	185	4	]	]	-RRB-
cord-278081-tk7vn1v1	185	5	.	.	.
cord-278081-tk7vn1v1	186	1	The	the	DT
cord-278081-tk7vn1v1	186	2	result	result	NN
cord-278081-tk7vn1v1	186	3	is	be	VBZ
cord-278081-tk7vn1v1	186	4	the	the	DT
cord-278081-tk7vn1v1	186	5	Barr	Barr	NNP
cord-278081-tk7vn1v1	186	6	body	body	NN
cord-278081-tk7vn1v1	186	7	which	which	WDT
cord-278081-tk7vn1v1	186	8	appears	appear	VBZ
cord-278081-tk7vn1v1	186	9	as	as	IN
cord-278081-tk7vn1v1	186	10	a	a	DT
cord-278081-tk7vn1v1	186	11	dense	dense	JJ
cord-278081-tk7vn1v1	186	12	heterochromatic	heterochromatic	JJ
cord-278081-tk7vn1v1	186	13	structure	structure	NN
cord-278081-tk7vn1v1	186	14	near	near	IN
cord-278081-tk7vn1v1	186	15	the	the	DT
cord-278081-tk7vn1v1	186	16	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	186	17	membrane	membrane	NN
cord-278081-tk7vn1v1	186	18	.	.	.
cord-278081-tk7vn1v1	187	1	The	the	DT
cord-278081-tk7vn1v1	187	2	bulk	bulk	NN
cord-278081-tk7vn1v1	187	3	of	of	IN
cord-278081-tk7vn1v1	187	4	the	the	DT
cord-278081-tk7vn1v1	187	5	heterochromatic	heterochromatic	JJ
cord-278081-tk7vn1v1	187	6	core	core	NN
cord-278081-tk7vn1v1	187	7	contains	contain	VBZ
cord-278081-tk7vn1v1	187	8	Xq	Xq	NNP
cord-278081-tk7vn1v1	187	9	genes	gene	NNS
cord-278081-tk7vn1v1	187	10	with	with	IN
cord-278081-tk7vn1v1	187	11	some	some	DT
cord-278081-tk7vn1v1	187	12	Xp	Xp	NNP
cord-278081-tk7vn1v1	187	13	genes	gene	NNS
cord-278081-tk7vn1v1	187	14	,	,	,
cord-278081-tk7vn1v1	187	15	and	and	CC
cord-278081-tk7vn1v1	187	16	the	the	DT
cord-278081-tk7vn1v1	187	17	euchromatic	euchromatic	JJ
cord-278081-tk7vn1v1	187	18	-	-	HYPH
cord-278081-tk7vn1v1	187	19	like	like	JJ
cord-278081-tk7vn1v1	187	20	surface	surface	NN
cord-278081-tk7vn1v1	187	21	layer	layer	NN
cord-278081-tk7vn1v1	187	22	has	have	VBZ
cord-278081-tk7vn1v1	187	23	primarily	primarily	RB
cord-278081-tk7vn1v1	187	24	Xp	Xp	NNP
cord-278081-tk7vn1v1	187	25	genes	gene	NNS
cord-278081-tk7vn1v1	187	26	that	that	WDT
cord-278081-tk7vn1v1	187	27	are	be	VBP
cord-278081-tk7vn1v1	187	28	:	:	:
cord-278081-tk7vn1v1	187	29	actively	actively	RB
cord-278081-tk7vn1v1	187	30	expressed	express	VBN
cord-278081-tk7vn1v1	187	31	;	;	:
cord-278081-tk7vn1v1	187	32	potentiated	potentiate	VBN
cord-278081-tk7vn1v1	187	33	for	for	IN
cord-278081-tk7vn1v1	187	34	expression	expression	NN
cord-278081-tk7vn1v1	187	35	;	;	,
cord-278081-tk7vn1v1	187	36	or	or	CC
cord-278081-tk7vn1v1	187	37	silenced	silence	VBN
cord-278081-tk7vn1v1	187	38	but	but	CC
cord-278081-tk7vn1v1	187	39	adjacent	adjacent	JJ
cord-278081-tk7vn1v1	187	40	to	to	IN
cord-278081-tk7vn1v1	187	41	expressed	express	VBN
cord-278081-tk7vn1v1	187	42	genes	gene	NNS
cord-278081-tk7vn1v1	187	43	.	.	.
cord-278081-tk7vn1v1	188	1	Particularly	particularly	RB
cord-278081-tk7vn1v1	188	2	interesting	interesting	JJ
cord-278081-tk7vn1v1	188	3	in	in	IN
cord-278081-tk7vn1v1	188	4	the	the	DT
cord-278081-tk7vn1v1	188	5	Xp	Xp	NNP
cord-278081-tk7vn1v1	188	6	is	be	VBZ
cord-278081-tk7vn1v1	188	7	the	the	DT
cord-278081-tk7vn1v1	188	8	pseudo	pseudo	JJ
cord-278081-tk7vn1v1	188	9	-	-	JJ
cord-278081-tk7vn1v1	188	10	autosomal	autosomal	JJ
cord-278081-tk7vn1v1	188	11	region	region	NN
cord-278081-tk7vn1v1	188	12	1	1	CD
cord-278081-tk7vn1v1	188	13	(	(	-LRB-
cord-278081-tk7vn1v1	188	14	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	188	15	)	)	-RRB-
cord-278081-tk7vn1v1	188	16	which	which	WDT
cord-278081-tk7vn1v1	188	17	has	have	VBZ
cord-278081-tk7vn1v1	188	18	an	an	DT
cord-278081-tk7vn1v1	188	19	abundance	abundance	NN
cord-278081-tk7vn1v1	188	20	of	of	IN
cord-278081-tk7vn1v1	188	21	Alu	Alu	NNP
cord-278081-tk7vn1v1	188	22	elements	element	NNS
cord-278081-tk7vn1v1	188	23	(	(	-LRB-
cord-278081-tk7vn1v1	188	24	46	46	CD
cord-278081-tk7vn1v1	188	25	)	)	-RRB-
cord-278081-tk7vn1v1	188	26	.	.	.
cord-278081-tk7vn1v1	189	1	In	in	IN
cord-278081-tk7vn1v1	189	2	addition	addition	NN
cord-278081-tk7vn1v1	189	3	,	,	,
cord-278081-tk7vn1v1	189	4	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	189	5	contains	contain	VBZ
cord-278081-tk7vn1v1	189	6	a	a	DT
cord-278081-tk7vn1v1	189	7	"	"	``
cord-278081-tk7vn1v1	189	8	hot	hot	JJ
cord-278081-tk7vn1v1	189	9	"	"	''
cord-278081-tk7vn1v1	189	10	LINE-1	line-1	NN
cord-278081-tk7vn1v1	189	11	sequence	sequence	NN
cord-278081-tk7vn1v1	189	12	that	that	WDT
cord-278081-tk7vn1v1	189	13	can	can	MD
cord-278081-tk7vn1v1	189	14	code	code	VB
cord-278081-tk7vn1v1	189	15	for	for	IN
cord-278081-tk7vn1v1	189	16	a	a	DT
cord-278081-tk7vn1v1	189	17	fully	fully	RB
cord-278081-tk7vn1v1	189	18	functional	functional	JJ
cord-278081-tk7vn1v1	189	19	reverse	reverse	NN
cord-278081-tk7vn1v1	189	20	transcriptase	transcriptase	NN
cord-278081-tk7vn1v1	189	21	.	.	.
cord-278081-tk7vn1v1	190	1	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	190	2	also	also	RB
cord-278081-tk7vn1v1	190	3	contains	contain	VBZ
cord-278081-tk7vn1v1	190	4	a	a	DT
cord-278081-tk7vn1v1	190	5	fragile	fragile	JJ
cord-278081-tk7vn1v1	190	6	site	site	NN
cord-278081-tk7vn1v1	190	7	(	(	-LRB-
cord-278081-tk7vn1v1	190	8	FRAXB	FRAXB	NNP
cord-278081-tk7vn1v1	190	9	)	)	-RRB-
cord-278081-tk7vn1v1	190	10	.	.	.
cord-278081-tk7vn1v1	191	1	Fragile	fragile	JJ
cord-278081-tk7vn1v1	191	2	sites	site	NNS
cord-278081-tk7vn1v1	191	3	are	be	VBP
cord-278081-tk7vn1v1	191	4	preferential	preferential	JJ
cord-278081-tk7vn1v1	191	5	locations	location	NNS
cord-278081-tk7vn1v1	191	6	for	for	IN
cord-278081-tk7vn1v1	191	7	viral	viral	JJ
cord-278081-tk7vn1v1	191	8	insertions	insertion	NNS
cord-278081-tk7vn1v1	191	9	.	.	.
cord-278081-tk7vn1v1	192	1	And	and	CC
cord-278081-tk7vn1v1	192	2	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	192	3	on	on	IN
cord-278081-tk7vn1v1	192	4	the	the	DT
cord-278081-tk7vn1v1	192	5	Xi	Xi	NNP
cord-278081-tk7vn1v1	192	6	contains	contain	VBZ
cord-278081-tk7vn1v1	192	7	epigenetically	epigenetically	RB
cord-278081-tk7vn1v1	192	8	silenced	silence	VBN
cord-278081-tk7vn1v1	192	9	genes	gene	NNS
cord-278081-tk7vn1v1	192	10	for	for	IN
cord-278081-tk7vn1v1	192	11	spermine	spermine	JJ
cord-278081-tk7vn1v1	192	12	synthase	synthase	NN
cord-278081-tk7vn1v1	192	13	(	(	-LRB-
cord-278081-tk7vn1v1	192	14	SMS	sms	NN
cord-278081-tk7vn1v1	192	15	)	)	-RRB-
cord-278081-tk7vn1v1	192	16	and	and	CC
cord-278081-tk7vn1v1	192	17	spermidine/	spermidine/	CD
cord-278081-tk7vn1v1	192	18	spermine	spermine	NNP
cord-278081-tk7vn1v1	192	19	N1	N1	NNP
cord-278081-tk7vn1v1	192	20	acetyltransferase	acetyltransferase	NN
cord-278081-tk7vn1v1	192	21	(	(	-LRB-
cord-278081-tk7vn1v1	192	22	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	192	23	)	)	-RRB-
cord-278081-tk7vn1v1	192	24	.	.	.
cord-278081-tk7vn1v1	193	1	Overexpression	overexpression	NN
cord-278081-tk7vn1v1	193	2	of	of	IN
cord-278081-tk7vn1v1	193	3	SMS	SMS	NNP
cord-278081-tk7vn1v1	193	4	and/or	and/or	CC
cord-278081-tk7vn1v1	193	5	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	193	6	that	that	WDT
cord-278081-tk7vn1v1	193	7	could	could	MD
cord-278081-tk7vn1v1	193	8	occur	occur	VB
cord-278081-tk7vn1v1	193	9	with	with	IN
cord-278081-tk7vn1v1	193	10	disruption	disruption	NN
cord-278081-tk7vn1v1	193	11	of	of	IN
cord-278081-tk7vn1v1	193	12	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	193	13	silencing	silencing	NN
cord-278081-tk7vn1v1	193	14	on	on	IN
cord-278081-tk7vn1v1	193	15	the	the	DT
cord-278081-tk7vn1v1	193	16	Xi	Xi	NNP
cord-278081-tk7vn1v1	193	17	can	can	MD
cord-278081-tk7vn1v1	193	18	impact	impact	VB
cord-278081-tk7vn1v1	193	19	cellular	cellular	JJ
cord-278081-tk7vn1v1	193	20	methylation	methylation	NN
cord-278081-tk7vn1v1	193	21	and	and	CC
cord-278081-tk7vn1v1	193	22	polyamine	polyamine	NN
cord-278081-tk7vn1v1	193	23	types	type	NNS
cord-278081-tk7vn1v1	193	24	and	and	CC
cord-278081-tk7vn1v1	193	25	levels	level	NNS
cord-278081-tk7vn1v1	193	26	.	.	.
cord-278081-tk7vn1v1	194	1	This	this	DT
cord-278081-tk7vn1v1	194	2	could	could	MD
cord-278081-tk7vn1v1	194	3	also	also	RB
cord-278081-tk7vn1v1	194	4	impact	impact	VB
cord-278081-tk7vn1v1	194	5	polyamine	polyamine	NN
cord-278081-tk7vn1v1	194	6	activity	activity	NN
cord-278081-tk7vn1v1	194	7	in	in	IN
cord-278081-tk7vn1v1	194	8	the	the	DT
cord-278081-tk7vn1v1	194	9	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	194	10	.	.	.
cord-278081-tk7vn1v1	195	1	under	under	RB
cord-278081-tk7vn1v1	195	2	-	-	HYPH
cord-278081-tk7vn1v1	195	3	appreciated	appreciate	VBN
cord-278081-tk7vn1v1	195	4	aspects	aspect	NNS
cord-278081-tk7vn1v1	195	5	of	of	IN
cord-278081-tk7vn1v1	195	6	epigenetics	epigenetic	NNS
cord-278081-tk7vn1v1	195	7	and	and	CC
cord-278081-tk7vn1v1	195	8	could	could	MD
cord-278081-tk7vn1v1	195	9	come	come	VB
cord-278081-tk7vn1v1	195	10	into	into	IN
cord-278081-tk7vn1v1	195	11	play	play	NN
cord-278081-tk7vn1v1	195	12	when	when	WRB
cord-278081-tk7vn1v1	195	13	the	the	DT
cord-278081-tk7vn1v1	195	14	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	195	15	encroaches	encroach	VBZ
cord-278081-tk7vn1v1	195	16	on	on	IN
cord-278081-tk7vn1v1	195	17	surrounding	surround	VBG
cord-278081-tk7vn1v1	195	18	chromatin	chromatin	NN
cord-278081-tk7vn1v1	195	19	.	.	.
cord-278081-tk7vn1v1	196	1	Normally	normally	RB
cord-278081-tk7vn1v1	196	2	males	male	NNS
cord-278081-tk7vn1v1	196	3	have	have	VBP
cord-278081-tk7vn1v1	196	4	only	only	RB
cord-278081-tk7vn1v1	196	5	one	one	CD
cord-278081-tk7vn1v1	196	6	X	x	NN
cord-278081-tk7vn1v1	196	7	chromosome	chromosome	NN
cord-278081-tk7vn1v1	196	8	whereas	whereas	IN
cord-278081-tk7vn1v1	196	9	females	female	NNS
cord-278081-tk7vn1v1	196	10	have	have	VBP
cord-278081-tk7vn1v1	196	11	two	two	CD
cord-278081-tk7vn1v1	196	12	X	x	NN
cord-278081-tk7vn1v1	196	13	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	196	14	.	.	.
cord-278081-tk7vn1v1	197	1	Most	Most	JJS
cord-278081-tk7vn1v1	197	2	genes	gene	NNS
cord-278081-tk7vn1v1	197	3	on	on	IN
cord-278081-tk7vn1v1	197	4	the	the	DT
cord-278081-tk7vn1v1	197	5	X	x	NN
cord-278081-tk7vn1v1	197	6	are	be	VBP
cord-278081-tk7vn1v1	197	7	not	not	RB
cord-278081-tk7vn1v1	197	8	sex	sex	NN
cord-278081-tk7vn1v1	197	9	-	-	HYPH
cord-278081-tk7vn1v1	197	10	related	relate	VBN
cord-278081-tk7vn1v1	197	11	so	so	IN
cord-278081-tk7vn1v1	197	12	females	female	NNS
cord-278081-tk7vn1v1	197	13	only	only	RB
cord-278081-tk7vn1v1	197	14	need	need	VBP
cord-278081-tk7vn1v1	197	15	one	one	CD
cord-278081-tk7vn1v1	197	16	active	active	JJ
cord-278081-tk7vn1v1	197	17	X	x	NN
cord-278081-tk7vn1v1	197	18	chromosome	chromosome	NN
cord-278081-tk7vn1v1	197	19	.	.	.
cord-278081-tk7vn1v1	198	1	Therefore	therefore	RB
cord-278081-tk7vn1v1	198	2	,	,	,
cord-278081-tk7vn1v1	198	3	early	early	RB
cord-278081-tk7vn1v1	198	4	in	in	IN
cord-278081-tk7vn1v1	198	5	embryogenesis	embryogenesis	NN
cord-278081-tk7vn1v1	198	6	,	,	,
cord-278081-tk7vn1v1	198	7	each	each	DT
cord-278081-tk7vn1v1	198	8	female	female	JJ
cord-278081-tk7vn1v1	198	9	cell	cell	NN
cord-278081-tk7vn1v1	198	10	inactivates	inactivate	VBZ
cord-278081-tk7vn1v1	198	11	one	one	CD
cord-278081-tk7vn1v1	198	12	X	x	NN
cord-278081-tk7vn1v1	198	13	chromosome	chromosome	NN
cord-278081-tk7vn1v1	198	14	,	,	,
cord-278081-tk7vn1v1	198	15	either	either	CC
cord-278081-tk7vn1v1	198	16	the	the	DT
cord-278081-tk7vn1v1	198	17	maternally	maternally	RB
cord-278081-tk7vn1v1	198	18	derived	derive	VBN
cord-278081-tk7vn1v1	198	19	or	or	CC
cord-278081-tk7vn1v1	198	20	the	the	DT
cord-278081-tk7vn1v1	198	21	paternally	paternally	RB
cord-278081-tk7vn1v1	198	22	derived	derive	VBN
cord-278081-tk7vn1v1	198	23	X	x	NN
cord-278081-tk7vn1v1	198	24	,	,	,
cord-278081-tk7vn1v1	198	25	and	and	CC
cord-278081-tk7vn1v1	198	26	each	each	DT
cord-278081-tk7vn1v1	198	27	daughter	daughter	NN
cord-278081-tk7vn1v1	198	28	cell	cell	NN
cord-278081-tk7vn1v1	198	29	will	will	MD
cord-278081-tk7vn1v1	198	30	inherit	inherit	VB
cord-278081-tk7vn1v1	198	31	that	that	DT
cord-278081-tk7vn1v1	198	32	inactivation	inactivation	NN
cord-278081-tk7vn1v1	198	33	pattern	pattern	NN
cord-278081-tk7vn1v1	198	34	.	.	.
cord-278081-tk7vn1v1	199	1	The	the	DT
cord-278081-tk7vn1v1	199	2	process	process	NN
cord-278081-tk7vn1v1	199	3	of	of	IN
cord-278081-tk7vn1v1	199	4	X	x	NN
cord-278081-tk7vn1v1	199	5	chromosome	chromosome	NN
cord-278081-tk7vn1v1	199	6	inactivation	inactivation	NN
cord-278081-tk7vn1v1	199	7	[	[	-LRB-
cord-278081-tk7vn1v1	199	8	reviewed	review	VBN
cord-278081-tk7vn1v1	199	9	in	in	IN
cord-278081-tk7vn1v1	199	10	Ref	Ref	NNP
cord-278081-tk7vn1v1	199	11	.	.	.
cord-278081-tk7vn1v1	200	1	(	(	-LRB-
cord-278081-tk7vn1v1	200	2	86	86	CD
cord-278081-tk7vn1v1	200	3	)	)	-RRB-
cord-278081-tk7vn1v1	200	4	]	]	-RRB-
cord-278081-tk7vn1v1	200	5	,	,	,
cord-278081-tk7vn1v1	200	6	which	which	WDT
cord-278081-tk7vn1v1	200	7	results	result	VBZ
cord-278081-tk7vn1v1	200	8	in	in	IN
cord-278081-tk7vn1v1	200	9	the	the	DT
cord-278081-tk7vn1v1	200	10	heterochromatic	heterochromatic	JJ
cord-278081-tk7vn1v1	200	11	Barr	Barr	NNP
cord-278081-tk7vn1v1	200	12	body	body	NN
cord-278081-tk7vn1v1	200	13	,	,	,
cord-278081-tk7vn1v1	200	14	begins	begin	VBZ
cord-278081-tk7vn1v1	200	15	from	from	IN
cord-278081-tk7vn1v1	200	16	the	the	DT
cord-278081-tk7vn1v1	200	17	X	x	NN
cord-278081-tk7vn1v1	200	18	inactivation	inactivation	NN
cord-278081-tk7vn1v1	200	19	center	center	NN
cord-278081-tk7vn1v1	200	20	at	at	IN
cord-278081-tk7vn1v1	200	21	Xq13	Xq13	.
cord-278081-tk7vn1v1	201	1	of	of	IN
cord-278081-tk7vn1v1	201	2	the	the	DT
cord-278081-tk7vn1v1	201	3	X	X	NNP
cord-278081-tk7vn1v1	201	4	chromosome	chromosome	NN
cord-278081-tk7vn1v1	201	5	's	's	POS
cord-278081-tk7vn1v1	201	6	long	long	JJ
cord-278081-tk7vn1v1	201	7	arm	arm	NN
cord-278081-tk7vn1v1	201	8	(	(	-LRB-
cord-278081-tk7vn1v1	201	9	Xq	xq	NN
cord-278081-tk7vn1v1	201	10	)	)	-RRB-
cord-278081-tk7vn1v1	202	1	(	(	-LRB-
cord-278081-tk7vn1v1	202	2	Figure	figure	NN
cord-278081-tk7vn1v1	202	3	3	3	CD
cord-278081-tk7vn1v1	202	4	)	)	-RRB-
cord-278081-tk7vn1v1	202	5	.	.	.
cord-278081-tk7vn1v1	203	1	Approximately	approximately	RB
cord-278081-tk7vn1v1	203	2	95	95	CD
cord-278081-tk7vn1v1	203	3	%	%	NN
cord-278081-tk7vn1v1	203	4	of	of	IN
cord-278081-tk7vn1v1	203	5	genes	gene	NNS
cord-278081-tk7vn1v1	203	6	on	on	IN
cord-278081-tk7vn1v1	203	7	the	the	DT
cord-278081-tk7vn1v1	203	8	Xq	Xq	NNP
cord-278081-tk7vn1v1	203	9	and	and	CC
cord-278081-tk7vn1v1	203	10	65	65	CD
cord-278081-tk7vn1v1	203	11	%	%	NN
cord-278081-tk7vn1v1	203	12	of	of	IN
cord-278081-tk7vn1v1	203	13	genes	gene	NNS
cord-278081-tk7vn1v1	203	14	on	on	IN
cord-278081-tk7vn1v1	203	15	the	the	DT
cord-278081-tk7vn1v1	203	16	short	short	JJ
cord-278081-tk7vn1v1	203	17	arm	arm	NN
cord-278081-tk7vn1v1	203	18	(	(	-LRB-
cord-278081-tk7vn1v1	203	19	Xp	Xp	NNP
cord-278081-tk7vn1v1	203	20	)	)	-RRB-
cord-278081-tk7vn1v1	203	21	are	be	VBP
cord-278081-tk7vn1v1	203	22	inactive	inactive	JJ
cord-278081-tk7vn1v1	203	23	and	and	CC
cord-278081-tk7vn1v1	203	24	form	form	VB
cord-278081-tk7vn1v1	203	25	the	the	DT
cord-278081-tk7vn1v1	203	26	heterochromatic	heterochromatic	JJ
cord-278081-tk7vn1v1	203	27	core	core	NN
cord-278081-tk7vn1v1	203	28	of	of	IN
cord-278081-tk7vn1v1	203	29	the	the	DT
cord-278081-tk7vn1v1	203	30	Barr	Barr	NNP
cord-278081-tk7vn1v1	203	31	body	body	NN
cord-278081-tk7vn1v1	203	32	(	(	-LRB-
cord-278081-tk7vn1v1	203	33	87	87	CD
cord-278081-tk7vn1v1	203	34	)	)	-RRB-
cord-278081-tk7vn1v1	203	35	.	.	.
cord-278081-tk7vn1v1	204	1	The	the	DT
cord-278081-tk7vn1v1	204	2	surface	surface	NN
cord-278081-tk7vn1v1	204	3	of	of	IN
cord-278081-tk7vn1v1	204	4	the	the	DT
cord-278081-tk7vn1v1	204	5	Barr	Barr	NNP
cord-278081-tk7vn1v1	204	6	body	body	NN
cord-278081-tk7vn1v1	204	7	would	would	MD
cord-278081-tk7vn1v1	204	8	be	be	VB
cord-278081-tk7vn1v1	204	9	more	more	RBR
cord-278081-tk7vn1v1	204	10	characteristic	characteristic	JJ
cord-278081-tk7vn1v1	204	11	of	of	IN
cord-278081-tk7vn1v1	204	12	euchromatin	euchromatin	NN
cord-278081-tk7vn1v1	204	13	with	with	IN
cord-278081-tk7vn1v1	204	14	genes	gene	NNS
cord-278081-tk7vn1v1	204	15	that	that	WDT
cord-278081-tk7vn1v1	204	16	escape	escape	VBP
cord-278081-tk7vn1v1	204	17	inactivation	inactivation	NN
cord-278081-tk7vn1v1	204	18	and	and	CC
cord-278081-tk7vn1v1	204	19	some	some	DT
cord-278081-tk7vn1v1	204	20	inactive	inactive	JJ
cord-278081-tk7vn1v1	204	21	genes	gene	NNS
cord-278081-tk7vn1v1	204	22	that	that	WDT
cord-278081-tk7vn1v1	204	23	are	be	VBP
cord-278081-tk7vn1v1	204	24	surrounded	surround	VBN
cord-278081-tk7vn1v1	204	25	by	by	IN
cord-278081-tk7vn1v1	204	26	active	active	JJ
cord-278081-tk7vn1v1	204	27	genes	gene	NNS
cord-278081-tk7vn1v1	204	28	or	or	CC
cord-278081-tk7vn1v1	204	29	genes	gene	NNS
cord-278081-tk7vn1v1	204	30	potentiated	potentiate	VBN
cord-278081-tk7vn1v1	204	31	for	for	IN
cord-278081-tk7vn1v1	204	32	activity	activity	NN
cord-278081-tk7vn1v1	204	33	.	.	.
cord-278081-tk7vn1v1	205	1	Especially	especially	RB
cord-278081-tk7vn1v1	205	2	interesting	interesting	JJ
cord-278081-tk7vn1v1	205	3	are	be	VBP
cord-278081-tk7vn1v1	205	4	genes	gene	NNS
cord-278081-tk7vn1v1	205	5	on	on	IN
cord-278081-tk7vn1v1	205	6	the	the	DT
cord-278081-tk7vn1v1	205	7	Xp	Xp	NNP
cord-278081-tk7vn1v1	205	8	from	from	IN
cord-278081-tk7vn1v1	205	9	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	205	10	to	to	IN
cord-278081-tk7vn1v1	205	11	the	the	DT
cord-278081-tk7vn1v1	205	12	Xp	Xp	NNP
cord-278081-tk7vn1v1	205	13	telomere	telomere	NN
cord-278081-tk7vn1v1	205	14	,	,	,
cord-278081-tk7vn1v1	205	15	including	include	VBG
cord-278081-tk7vn1v1	205	16	the	the	DT
cord-278081-tk7vn1v1	205	17	pseudo	pseudo	JJ
cord-278081-tk7vn1v1	205	18	-	-	JJ
cord-278081-tk7vn1v1	205	19	autosomal	autosomal	JJ
cord-278081-tk7vn1v1	205	20	region	region	NN
cord-278081-tk7vn1v1	205	21	1	1	CD
cord-278081-tk7vn1v1	205	22	(	(	-LRB-
cord-278081-tk7vn1v1	205	23	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	205	24	)	)	-RRB-
cord-278081-tk7vn1v1	205	25	.	.	.
cord-278081-tk7vn1v1	206	1	These	these	DT
cord-278081-tk7vn1v1	206	2	would	would	MD
cord-278081-tk7vn1v1	206	3	be	be	VB
cord-278081-tk7vn1v1	206	4	at	at	IN
cord-278081-tk7vn1v1	206	5	the	the	DT
cord-278081-tk7vn1v1	206	6	surface	surface	NN
cord-278081-tk7vn1v1	206	7	of	of	IN
cord-278081-tk7vn1v1	206	8	the	the	DT
cord-278081-tk7vn1v1	206	9	Barr	Barr	NNP
cord-278081-tk7vn1v1	206	10	body	body	NN
cord-278081-tk7vn1v1	206	11	and	and	CC
cord-278081-tk7vn1v1	206	12	more	more	RBR
cord-278081-tk7vn1v1	206	13	readily	readily	RB
cord-278081-tk7vn1v1	206	14	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	206	15	by	by	IN
cord-278081-tk7vn1v1	206	16	an	an	DT
cord-278081-tk7vn1v1	206	17	expanding	expand	VBG
cord-278081-tk7vn1v1	206	18	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	206	19	under	under	IN
cord-278081-tk7vn1v1	206	20	stress	stress	NN
cord-278081-tk7vn1v1	206	21	.	.	.
cord-278081-tk7vn1v1	207	1	SMS	SMS	NNP
cord-278081-tk7vn1v1	207	2	and	and	CC
cord-278081-tk7vn1v1	207	3	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	207	4	/	/	SYM
cord-278081-tk7vn1v1	207	5	spermine	spermine	JJ
cord-278081-tk7vn1v1	207	6	N1	N1	NNP
cord-278081-tk7vn1v1	207	7	acetyltransferase	acetyltransferase	NN
cord-278081-tk7vn1v1	207	8	(	(	-LRB-
cord-278081-tk7vn1v1	207	9	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	207	10	)	)	-RRB-
cord-278081-tk7vn1v1	207	11	are	be	VBP
cord-278081-tk7vn1v1	207	12	involved	involve	VBN
cord-278081-tk7vn1v1	207	13	in	in	IN
cord-278081-tk7vn1v1	207	14	polyamine	polyamine	NN
cord-278081-tk7vn1v1	207	15	synthesis	synthesis	NN
cord-278081-tk7vn1v1	207	16	and	and	CC
cord-278081-tk7vn1v1	207	17	recycling	recycling	NN
cord-278081-tk7vn1v1	207	18	,	,	,
cord-278081-tk7vn1v1	207	19	respectively	respectively	RB
cord-278081-tk7vn1v1	207	20	,	,	,
cord-278081-tk7vn1v1	207	21	and	and	CC
cord-278081-tk7vn1v1	207	22	normally	normally	RB
cord-278081-tk7vn1v1	207	23	SMS	SMS	NNP
cord-278081-tk7vn1v1	207	24	and	and	CC
cord-278081-tk7vn1v1	207	25	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	207	26	,	,	,
cord-278081-tk7vn1v1	207	27	located	locate	VBN
cord-278081-tk7vn1v1	207	28	at	at	IN
cord-278081-tk7vn1v1	207	29	Xp22.1	Xp22.1	NNP
cord-278081-tk7vn1v1	207	30	,	,	,
cord-278081-tk7vn1v1	207	31	are	be	VBP
cord-278081-tk7vn1v1	207	32	inactive	inactive	JJ
cord-278081-tk7vn1v1	207	33	on	on	IN
cord-278081-tk7vn1v1	207	34	the	the	DT
cord-278081-tk7vn1v1	207	35	Barr	Barr	NNP
cord-278081-tk7vn1v1	207	36	body	body	NN
cord-278081-tk7vn1v1	207	37	(	(	-LRB-
cord-278081-tk7vn1v1	207	38	87	87	CD
cord-278081-tk7vn1v1	207	39	)	)	-RRB-
cord-278081-tk7vn1v1	207	40	.	.	.
cord-278081-tk7vn1v1	208	1	However	however	RB
cord-278081-tk7vn1v1	208	2	,	,	,
cord-278081-tk7vn1v1	208	3	disruption	disruption	NN
cord-278081-tk7vn1v1	208	4	of	of	IN
cord-278081-tk7vn1v1	208	5	the	the	DT
cord-278081-tk7vn1v1	208	6	Barr	Barr	NNP
cord-278081-tk7vn1v1	208	7	body	body	NN
cord-278081-tk7vn1v1	208	8	by	by	IN
cord-278081-tk7vn1v1	208	9	enlargement	enlargement	NN
cord-278081-tk7vn1v1	208	10	of	of	IN
cord-278081-tk7vn1v1	208	11	the	the	DT
cord-278081-tk7vn1v1	208	12	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	208	13	,	,	,
cord-278081-tk7vn1v1	208	14	as	as	IN
cord-278081-tk7vn1v1	208	15	shown	show	VBN
cord-278081-tk7vn1v1	208	16	in	in	IN
cord-278081-tk7vn1v1	208	17	Figure	Figure	NNP
cord-278081-tk7vn1v1	208	18	2B	2b	CD
cord-278081-tk7vn1v1	208	19	,	,	,
cord-278081-tk7vn1v1	208	20	could	could	MD
cord-278081-tk7vn1v1	208	21	lead	lead	VB
cord-278081-tk7vn1v1	208	22	to	to	IN
cord-278081-tk7vn1v1	208	23	reactivation	reactivation	NN
cord-278081-tk7vn1v1	208	24	of	of	IN
cord-278081-tk7vn1v1	208	25	SMS	sms	NN
cord-278081-tk7vn1v1	208	26	and	and	CC
cord-278081-tk7vn1v1	208	27	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	208	28	.	.	.
cord-278081-tk7vn1v1	209	1	This	this	DT
cord-278081-tk7vn1v1	209	2	would	would	MD
cord-278081-tk7vn1v1	209	3	result	result	VB
cord-278081-tk7vn1v1	209	4	in	in	IN
cord-278081-tk7vn1v1	209	5	a	a	DT
cord-278081-tk7vn1v1	209	6	rapid	rapid	JJ
cord-278081-tk7vn1v1	209	7	increase	increase	NN
cord-278081-tk7vn1v1	209	8	in	in	IN
cord-278081-tk7vn1v1	209	9	polyamine	polyamine	NN
cord-278081-tk7vn1v1	209	10	synthesis	synthesis	NN
cord-278081-tk7vn1v1	209	11	and	and	CC
cord-278081-tk7vn1v1	209	12	recycling	recycling	NN
cord-278081-tk7vn1v1	209	13	beyond	beyond	IN
cord-278081-tk7vn1v1	209	14	what	what	WP
cord-278081-tk7vn1v1	209	15	was	be	VBD
cord-278081-tk7vn1v1	209	16	already	already	RB
cord-278081-tk7vn1v1	209	17	induced	induce	VBN
cord-278081-tk7vn1v1	209	18	by	by	IN
cord-278081-tk7vn1v1	209	19	the	the	DT
cord-278081-tk7vn1v1	209	20	host	host	NN
cord-278081-tk7vn1v1	209	21	cell	cell	NN
cord-278081-tk7vn1v1	209	22	and	and	CC
cord-278081-tk7vn1v1	209	23	the	the	DT
cord-278081-tk7vn1v1	209	24	viral	viral	JJ
cord-278081-tk7vn1v1	209	25	activity	activity	NN
cord-278081-tk7vn1v1	209	26	.	.	.
cord-278081-tk7vn1v1	210	1	There	there	EX
cord-278081-tk7vn1v1	210	2	would	would	MD
cord-278081-tk7vn1v1	210	3	be	be	VB
cord-278081-tk7vn1v1	210	4	an	an	DT
cord-278081-tk7vn1v1	210	5	increase	increase	NN
cord-278081-tk7vn1v1	210	6	in	in	IN
cord-278081-tk7vn1v1	210	7	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	210	8	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	210	9	by	by	IN
cord-278081-tk7vn1v1	210	10	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	210	11	that	that	WDT
cord-278081-tk7vn1v1	210	12	could	could	MD
cord-278081-tk7vn1v1	210	13	interfere	interfere	VB
cord-278081-tk7vn1v1	210	14	with	with	IN
cord-278081-tk7vn1v1	210	15	RNA	RNA	NNP
cord-278081-tk7vn1v1	210	16	folding	folding	NN
cord-278081-tk7vn1v1	210	17	and	and	CC
cord-278081-tk7vn1v1	210	18	,	,	,
cord-278081-tk7vn1v1	210	19	through	through	IN
cord-278081-tk7vn1v1	210	20	oxidation	oxidation	NN
cord-278081-tk7vn1v1	210	21	,	,	,
cord-278081-tk7vn1v1	210	22	generate	generate	VB
cord-278081-tk7vn1v1	210	23	putrescine	putrescine	NN
cord-278081-tk7vn1v1	210	24	which	which	WDT
cord-278081-tk7vn1v1	210	25	,	,	,
cord-278081-tk7vn1v1	210	26	in	in	IN
cord-278081-tk7vn1v1	210	27	turn	turn	NN
cord-278081-tk7vn1v1	210	28	,	,	,
cord-278081-tk7vn1v1	210	29	could	could	MD
cord-278081-tk7vn1v1	210	30	allosterically	allosterically	RB
cord-278081-tk7vn1v1	210	31	increase	increase	VB
cord-278081-tk7vn1v1	210	32	S	S	NNP
cord-278081-tk7vn1v1	210	33	-	-	HYPH
cord-278081-tk7vn1v1	210	34	adenosylmethionine	adenosylmethionine	NNP
cord-278081-tk7vn1v1	210	35	(	(	-LRB-
cord-278081-tk7vn1v1	210	36	SAM	SAM	NNP
cord-278081-tk7vn1v1	210	37	)	)	-RRB-
cord-278081-tk7vn1v1	210	38	decarboxylase	decarboxylase	NN
cord-278081-tk7vn1v1	210	39	activation	activation	NN
cord-278081-tk7vn1v1	210	40	reducing	reduce	VBG
cord-278081-tk7vn1v1	210	41	SAM	SAM	NNP
cord-278081-tk7vn1v1	210	42	needed	need	VBD
cord-278081-tk7vn1v1	210	43	for	for	IN
cord-278081-tk7vn1v1	210	44	DNA	dna	NN
cord-278081-tk7vn1v1	210	45	and	and	CC
cord-278081-tk7vn1v1	210	46	protein	protein	NN
cord-278081-tk7vn1v1	210	47	methylation	methylation	NN
cord-278081-tk7vn1v1	210	48	(	(	-LRB-
cord-278081-tk7vn1v1	210	49	72	72	CD
cord-278081-tk7vn1v1	210	50	)	)	-RRB-
cord-278081-tk7vn1v1	210	51	.	.	.
cord-278081-tk7vn1v1	211	1	Excess	excess	JJ
cord-278081-tk7vn1v1	211	2	free	free	JJ
cord-278081-tk7vn1v1	211	3	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	211	4	can	can	MD
cord-278081-tk7vn1v1	211	5	be	be	VB
cord-278081-tk7vn1v1	211	6	conjugated	conjugate	VBN
cord-278081-tk7vn1v1	211	7	to	to	IN
cord-278081-tk7vn1v1	211	8	proteins	protein	NNS
cord-278081-tk7vn1v1	211	9	by	by	IN
cord-278081-tk7vn1v1	211	10	transglutaminases	transglutaminase	NNS
cord-278081-tk7vn1v1	211	11	and	and	CC
cord-278081-tk7vn1v1	211	12	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	211	13	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	211	14	,	,	,
cord-278081-tk7vn1v1	211	15	and	and	CC
cord-278081-tk7vn1v1	211	16	the	the	DT
cord-278081-tk7vn1v1	211	17	conjugated	conjugated	JJ
cord-278081-tk7vn1v1	211	18	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	211	19	and	and	CC
cord-278081-tk7vn1v1	211	20	putrescine	putrescine	NN
cord-278081-tk7vn1v1	211	21	can	can	MD
cord-278081-tk7vn1v1	211	22	be	be	VB
cord-278081-tk7vn1v1	211	23	oxidized	oxidize	VBN
cord-278081-tk7vn1v1	211	24	to	to	IN
cord-278081-tk7vn1v1	211	25	toxic	toxic	JJ
cord-278081-tk7vn1v1	211	26	acrolein	acrolein	NN
cord-278081-tk7vn1v1	211	27	.	.	.
cord-278081-tk7vn1v1	212	1	There	there	EX
cord-278081-tk7vn1v1	212	2	is	be	VBZ
cord-278081-tk7vn1v1	212	3	a	a	DT
cord-278081-tk7vn1v1	212	4	close	close	JJ
cord-278081-tk7vn1v1	212	5	relationship	relationship	NN
cord-278081-tk7vn1v1	212	6	between	between	IN
cord-278081-tk7vn1v1	212	7	the	the	DT
cord-278081-tk7vn1v1	212	8	intensity	intensity	NN
cord-278081-tk7vn1v1	212	9	of	of	IN
cord-278081-tk7vn1v1	212	10	SjS	sjs	NN
cord-278081-tk7vn1v1	212	11	and	and	CC
cord-278081-tk7vn1v1	212	12	the	the	DT
cord-278081-tk7vn1v1	212	13	appearance	appearance	NN
cord-278081-tk7vn1v1	212	14	of	of	IN
cord-278081-tk7vn1v1	212	15	acrolein	acrolein	NN
cord-278081-tk7vn1v1	212	16	-	-	HYPH
cord-278081-tk7vn1v1	212	17	conjugated	conjugate	VBN
cord-278081-tk7vn1v1	212	18	proteins	protein	NNS
cord-278081-tk7vn1v1	212	19	(	(	-LRB-
cord-278081-tk7vn1v1	212	20	88	88	CD
cord-278081-tk7vn1v1	212	21	)	)	-RRB-
cord-278081-tk7vn1v1	212	22	.	.	.
cord-278081-tk7vn1v1	213	1	The	the	DT
cord-278081-tk7vn1v1	213	2	net	net	JJ
cord-278081-tk7vn1v1	213	3	effect	effect	NN
cord-278081-tk7vn1v1	213	4	of	of	IN
cord-278081-tk7vn1v1	213	5	expression	expression	NN
cord-278081-tk7vn1v1	213	6	of	of	IN
cord-278081-tk7vn1v1	213	7	SMS	SMS	NNP
cord-278081-tk7vn1v1	213	8	and	and	CC
cord-278081-tk7vn1v1	213	9	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	213	10	from	from	IN
cord-278081-tk7vn1v1	213	11	the	the	DT
cord-278081-tk7vn1v1	213	12	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	213	13	Barr	Barr	NNP
cord-278081-tk7vn1v1	213	14	body	body	NN
cord-278081-tk7vn1v1	213	15	is	be	VBZ
cord-278081-tk7vn1v1	213	16	dysregulation	dysregulation	NN
cord-278081-tk7vn1v1	213	17	of	of	IN
cord-278081-tk7vn1v1	213	18	polyamine	polyamine	NN
cord-278081-tk7vn1v1	213	19	levels	level	NNS
cord-278081-tk7vn1v1	213	20	.	.	.
cord-278081-tk7vn1v1	214	1	Add	add	VB
cord-278081-tk7vn1v1	214	2	to	to	IN
cord-278081-tk7vn1v1	214	3	this	this	DT
cord-278081-tk7vn1v1	214	4	the	the	DT
cord-278081-tk7vn1v1	214	5	fact	fact	NN
cord-278081-tk7vn1v1	214	6	that	that	IN
cord-278081-tk7vn1v1	214	7	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	214	8	can	can	MD
cord-278081-tk7vn1v1	214	9	undergo	undergo	VB
cord-278081-tk7vn1v1	214	10	super	super	JJ
cord-278081-tk7vn1v1	214	11	induction	induction	NN
cord-278081-tk7vn1v1	214	12	,	,	,
cord-278081-tk7vn1v1	214	13	meaning	mean	VBG
cord-278081-tk7vn1v1	214	14	there	there	EX
cord-278081-tk7vn1v1	214	15	could	could	MD
cord-278081-tk7vn1v1	214	16	be	be	VB
cord-278081-tk7vn1v1	214	17	a	a	DT
cord-278081-tk7vn1v1	214	18	several	several	JJ
cord-278081-tk7vn1v1	214	19	100-fold	100-fold	CD
cord-278081-tk7vn1v1	214	20	increase	increase	NN
cord-278081-tk7vn1v1	214	21	in	in	IN
cord-278081-tk7vn1v1	214	22	polyamine	polyamine	NN
cord-278081-tk7vn1v1	214	23	acetylation	acetylation	NN
cord-278081-tk7vn1v1	214	24	.	.	.
cord-278081-tk7vn1v1	215	1	In	in	IN
cord-278081-tk7vn1v1	215	2	the	the	DT
cord-278081-tk7vn1v1	215	3	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	215	4	,	,	,
cord-278081-tk7vn1v1	215	5	there	there	EX
cord-278081-tk7vn1v1	215	6	could	could	MD
cord-278081-tk7vn1v1	215	7	be	be	VB
cord-278081-tk7vn1v1	215	8	an	an	DT
cord-278081-tk7vn1v1	215	9	increase	increase	NN
cord-278081-tk7vn1v1	215	10	in	in	IN
cord-278081-tk7vn1v1	215	11	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	215	12	and	and	CC
cord-278081-tk7vn1v1	215	13	now	now	RB
cord-278081-tk7vn1v1	215	14	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	215	15	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	215	16	that	that	WDT
cord-278081-tk7vn1v1	215	17	interfere	interfere	VBP
cord-278081-tk7vn1v1	215	18	with	with	IN
cord-278081-tk7vn1v1	215	19	normal	normal	JJ
cord-278081-tk7vn1v1	215	20	RNA	RNA	NNP
cord-278081-tk7vn1v1	215	21	folding	folding	NN
cord-278081-tk7vn1v1	215	22	and	and	CC
cord-278081-tk7vn1v1	215	23	RNP	RNP	NNP
cord-278081-tk7vn1v1	215	24	assembly	assembly	NN
cord-278081-tk7vn1v1	215	25	.	.	.
cord-278081-tk7vn1v1	216	1	Once	once	IN
cord-278081-tk7vn1v1	216	2	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	216	3	becomes	become	VBZ
cord-278081-tk7vn1v1	216	4	active	active	JJ
cord-278081-tk7vn1v1	216	5	from	from	IN
cord-278081-tk7vn1v1	216	6	both	both	DT
cord-278081-tk7vn1v1	216	7	X	x	NN
cord-278081-tk7vn1v1	216	8	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	216	9	from	from	IN
cord-278081-tk7vn1v1	216	10	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	216	11	disruption	disruption	NN
cord-278081-tk7vn1v1	216	12	of	of	IN
cord-278081-tk7vn1v1	216	13	the	the	DT
cord-278081-tk7vn1v1	216	14	Barr	Barr	NNP
cord-278081-tk7vn1v1	216	15	body	body	NN
cord-278081-tk7vn1v1	216	16	,	,	,
cord-278081-tk7vn1v1	216	17	going	go	VBG
cord-278081-tk7vn1v1	216	18	forward	forward	RB
cord-278081-tk7vn1v1	216	19	there	there	EX
cord-278081-tk7vn1v1	216	20	could	could	MD
cord-278081-tk7vn1v1	216	21	be	be	VB
cord-278081-tk7vn1v1	216	22	a	a	DT
cord-278081-tk7vn1v1	216	23	drop	drop	NN
cord-278081-tk7vn1v1	216	24	in	in	IN
cord-278081-tk7vn1v1	216	25	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	216	26	during	during	IN
cord-278081-tk7vn1v1	216	27	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	216	28	stress	stress	NN
cord-278081-tk7vn1v1	216	29	events	event	NNS
cord-278081-tk7vn1v1	216	30	as	as	IN
cord-278081-tk7vn1v1	216	31	super	super	JJ
cord-278081-tk7vn1v1	216	32	induction	induction	NN
cord-278081-tk7vn1v1	216	33	of	of	IN
cord-278081-tk7vn1v1	216	34	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	216	35	acetylates	acetylate	NNS
cord-278081-tk7vn1v1	216	36	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	216	37	.	.	.
cord-278081-tk7vn1v1	217	1	It	-PRON-	PRP
cord-278081-tk7vn1v1	217	2	may	may	MD
cord-278081-tk7vn1v1	217	3	follow	follow	VB
cord-278081-tk7vn1v1	217	4	that	that	IN
cord-278081-tk7vn1v1	217	5	the	the	DT
cord-278081-tk7vn1v1	217	6	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	217	7	can	can	MD
cord-278081-tk7vn1v1	217	8	no	no	RB
cord-278081-tk7vn1v1	217	9	longer	longer	RB
cord-278081-tk7vn1v1	217	10	expand	expand	VB
cord-278081-tk7vn1v1	217	11	sufficiently	sufficiently	RB
cord-278081-tk7vn1v1	217	12	to	to	TO
cord-278081-tk7vn1v1	217	13	adapt	adapt	VB
cord-278081-tk7vn1v1	217	14	to	to	IN
cord-278081-tk7vn1v1	217	15	new	new	JJ
cord-278081-tk7vn1v1	217	16	stresses	stress	NNS
cord-278081-tk7vn1v1	217	17	and	and	CC
cord-278081-tk7vn1v1	217	18	the	the	DT
cord-278081-tk7vn1v1	217	19	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	217	20	can	can	MD
cord-278081-tk7vn1v1	217	21	no	no	RB
cord-278081-tk7vn1v1	217	22	longer	longer	RB
cord-278081-tk7vn1v1	217	23	work	work	VB
cord-278081-tk7vn1v1	217	24	efficiently	efficiently	RB
cord-278081-tk7vn1v1	217	25	in	in	IN
cord-278081-tk7vn1v1	217	26	proper	proper	JJ
cord-278081-tk7vn1v1	217	27	folding	folding	NN
cord-278081-tk7vn1v1	217	28	and	and	CC
cord-278081-tk7vn1v1	217	29	assembly	assembly	NN
cord-278081-tk7vn1v1	217	30	of	of	IN
cord-278081-tk7vn1v1	217	31	RNAs	RNAs	NNPS
cord-278081-tk7vn1v1	217	32	and	and	CC
cord-278081-tk7vn1v1	217	33	RNPs	RNPs	NNP
cord-278081-tk7vn1v1	217	34	,	,	,
cord-278081-tk7vn1v1	217	35	leading	lead	VBG
cord-278081-tk7vn1v1	217	36	to	to	IN
cord-278081-tk7vn1v1	217	37	creation	creation	NN
cord-278081-tk7vn1v1	217	38	of	of	IN
cord-278081-tk7vn1v1	217	39	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	217	40	.	.	.
cord-278081-tk7vn1v1	218	1	In	in	IN
cord-278081-tk7vn1v1	218	2	other	other	JJ
cord-278081-tk7vn1v1	218	3	words	word	NNS
cord-278081-tk7vn1v1	218	4	,	,	,
cord-278081-tk7vn1v1	218	5	an	an	DT
cord-278081-tk7vn1v1	218	6	initial	initial	JJ
cord-278081-tk7vn1v1	218	7	stress	stress	NN
cord-278081-tk7vn1v1	218	8	-	-	HYPH
cord-278081-tk7vn1v1	218	9	induced	induce	VBN
cord-278081-tk7vn1v1	218	10	polyamine	polyamine	NN
cord-278081-tk7vn1v1	218	11	-	-	HYPH
cord-278081-tk7vn1v1	218	12	driven	drive	VBN
cord-278081-tk7vn1v1	218	13	expansion	expansion	NN
cord-278081-tk7vn1v1	218	14	of	of	IN
cord-278081-tk7vn1v1	218	15	the	the	DT
cord-278081-tk7vn1v1	218	16	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	218	17	could	could	MD
cord-278081-tk7vn1v1	218	18	disrupt	disrupt	VB
cord-278081-tk7vn1v1	218	19	the	the	DT
cord-278081-tk7vn1v1	218	20	Barr	Barr	NNP
cord-278081-tk7vn1v1	218	21	body	body	NN
cord-278081-tk7vn1v1	218	22	leading	lead	VBG
cord-278081-tk7vn1v1	218	23	to	to	IN
cord-278081-tk7vn1v1	218	24	RNA	RNA	NNP
cord-278081-tk7vn1v1	218	25	pol	pol	NN
cord-278081-tk7vn1v1	218	26	III	III	NNP
cord-278081-tk7vn1v1	218	27	Alu	Alu	NNP
cord-278081-tk7vn1v1	218	28	transcript	transcript	NN
cord-278081-tk7vn1v1	218	29	-	-	HYPH
cord-278081-tk7vn1v1	218	30	driven	drive	VBN
cord-278081-tk7vn1v1	218	31	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	218	32	of	of	IN
cord-278081-tk7vn1v1	218	33	the	the	DT
cord-278081-tk7vn1v1	218	34	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	218	35	.	.	.
cord-278081-tk7vn1v1	219	1	Subsequently	subsequently	RB
cord-278081-tk7vn1v1	219	2	,	,	,
cord-278081-tk7vn1v1	219	3	with	with	IN
cord-278081-tk7vn1v1	219	4	reactivation	reactivation	NN
cord-278081-tk7vn1v1	219	5	of	of	IN
cord-278081-tk7vn1v1	219	6	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	219	7	from	from	IN
cord-278081-tk7vn1v1	219	8	the	the	DT
cord-278081-tk7vn1v1	219	9	Barr	Barr	NNP
cord-278081-tk7vn1v1	219	10	body	body	NN
cord-278081-tk7vn1v1	219	11	,	,	,
cord-278081-tk7vn1v1	219	12	it	-PRON-	PRP
cord-278081-tk7vn1v1	219	13	may	may	MD
cord-278081-tk7vn1v1	219	14	reduce	reduce	VB
cord-278081-tk7vn1v1	219	15	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	219	16	and	and	CC
cord-278081-tk7vn1v1	219	17	reduce	reduce	VB
cord-278081-tk7vn1v1	219	18	the	the	DT
cord-278081-tk7vn1v1	219	19	ability	ability	NN
cord-278081-tk7vn1v1	219	20	of	of	IN
cord-278081-tk7vn1v1	219	21	the	the	DT
cord-278081-tk7vn1v1	219	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	219	23	to	to	TO
cord-278081-tk7vn1v1	219	24	function	function	VB
cord-278081-tk7vn1v1	219	25	normally	normally	RB
cord-278081-tk7vn1v1	219	26	in	in	IN
cord-278081-tk7vn1v1	219	27	folding	folding	NN
cord-278081-tk7vn1v1	219	28	and	and	CC
cord-278081-tk7vn1v1	219	29	assembly	assembly	NN
cord-278081-tk7vn1v1	219	30	of	of	IN
cord-278081-tk7vn1v1	219	31	RNAs	RNAs	NNPS
cord-278081-tk7vn1v1	219	32	and	and	CC
cord-278081-tk7vn1v1	219	33	RNPs	rnp	NNS
cord-278081-tk7vn1v1	219	34	and	and	CC
cord-278081-tk7vn1v1	219	35	fail	fail	VB
cord-278081-tk7vn1v1	219	36	to	to	TO
cord-278081-tk7vn1v1	219	37	react	react	VB
cord-278081-tk7vn1v1	219	38	effectively	effectively	RB
cord-278081-tk7vn1v1	219	39	to	to	IN
cord-278081-tk7vn1v1	219	40	future	future	VB
cord-278081-tk7vn1v1	219	41	stressful	stressful	JJ
cord-278081-tk7vn1v1	219	42	events	event	NNS
cord-278081-tk7vn1v1	219	43	since	since	IN
cord-278081-tk7vn1v1	219	44	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	219	45	will	will	MD
cord-278081-tk7vn1v1	219	46	be	be	VB
cord-278081-tk7vn1v1	219	47	rapidly	rapidly	RB
cord-278081-tk7vn1v1	219	48	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	219	49	as	as	IN
cord-278081-tk7vn1v1	219	50	they	-PRON-	PRP
cord-278081-tk7vn1v1	219	51	are	be	VBP
cord-278081-tk7vn1v1	219	52	synthesized	synthesize	VBN
cord-278081-tk7vn1v1	219	53	.	.	.
cord-278081-tk7vn1v1	220	1	This	this	DT
cord-278081-tk7vn1v1	220	2	scenario	scenario	NN
cord-278081-tk7vn1v1	220	3	could	could	MD
cord-278081-tk7vn1v1	220	4	result	result	VB
cord-278081-tk7vn1v1	220	5	in	in	IN
cord-278081-tk7vn1v1	220	6	ongoing	ongoing	JJ
cord-278081-tk7vn1v1	220	7	generation	generation	NN
cord-278081-tk7vn1v1	220	8	of	of	IN
cord-278081-tk7vn1v1	220	9	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	220	10	,	,	,
cord-278081-tk7vn1v1	220	11	potentially	potentially	RB
cord-278081-tk7vn1v1	220	12	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	220	13	RNPs	rnp	NNS
cord-278081-tk7vn1v1	220	14	due	due	JJ
cord-278081-tk7vn1v1	220	15	to	to	IN
cord-278081-tk7vn1v1	220	16	the	the	DT
cord-278081-tk7vn1v1	220	17	compromised	compromised	JJ
cord-278081-tk7vn1v1	220	18	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	220	19	that	that	WDT
cord-278081-tk7vn1v1	220	20	lacks	lack	VBZ
cord-278081-tk7vn1v1	220	21	sufficient	sufficient	JJ
cord-278081-tk7vn1v1	220	22	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	220	23	.	.	.
cord-278081-tk7vn1v1	221	1	Another	another	DT
cord-278081-tk7vn1v1	221	2	problem	problem	NN
cord-278081-tk7vn1v1	221	3	that	that	WDT
cord-278081-tk7vn1v1	221	4	could	could	MD
cord-278081-tk7vn1v1	221	5	arise	arise	VB
cord-278081-tk7vn1v1	221	6	is	be	VBZ
cord-278081-tk7vn1v1	221	7	reverse	reverse	JJ
cord-278081-tk7vn1v1	221	8	transcription	transcription	NN
cord-278081-tk7vn1v1	221	9	.	.	.
cord-278081-tk7vn1v1	222	1	Most	Most	JJS
cord-278081-tk7vn1v1	222	2	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	222	3	elements	element	NNS
cord-278081-tk7vn1v1	222	4	have	have	VBP
cord-278081-tk7vn1v1	222	5	mutated	mutate	VBN
cord-278081-tk7vn1v1	222	6	sufficiently	sufficiently	RB
cord-278081-tk7vn1v1	222	7	so	so	IN
cord-278081-tk7vn1v1	222	8	that	that	IN
cord-278081-tk7vn1v1	222	9	they	-PRON-	PRP
cord-278081-tk7vn1v1	222	10	no	no	RB
cord-278081-tk7vn1v1	222	11	longer	longer	RB
cord-278081-tk7vn1v1	222	12	code	code	NN
cord-278081-tk7vn1v1	222	13	for	for	IN
cord-278081-tk7vn1v1	222	14	functional	functional	JJ
cord-278081-tk7vn1v1	222	15	reverse	reverse	JJ
cord-278081-tk7vn1v1	222	16	transcriptases	transcriptase	NNS
cord-278081-tk7vn1v1	222	17	.	.	.
cord-278081-tk7vn1v1	223	1	A	a	DT
cord-278081-tk7vn1v1	223	2	few	few	JJ
cord-278081-tk7vn1v1	223	3	,	,	,
cord-278081-tk7vn1v1	223	4	including	include	VBG
cord-278081-tk7vn1v1	223	5	one	one	CD
cord-278081-tk7vn1v1	223	6	in	in	IN
cord-278081-tk7vn1v1	223	7	Xp22	Xp22	NNP
cord-278081-tk7vn1v1	223	8	,	,	,
cord-278081-tk7vn1v1	223	9	can	can	MD
cord-278081-tk7vn1v1	223	10	still	still	RB
cord-278081-tk7vn1v1	223	11	produce	produce	VB
cord-278081-tk7vn1v1	223	12	functional	functional	JJ
cord-278081-tk7vn1v1	223	13	reverse	reverse	NN
cord-278081-tk7vn1v1	223	14	transcriptases	transcriptase	NNS
cord-278081-tk7vn1v1	223	15	but	but	CC
cord-278081-tk7vn1v1	223	16	are	be	VBP
cord-278081-tk7vn1v1	223	17	suppressed	suppress	VBN
cord-278081-tk7vn1v1	223	18	by	by	IN
cord-278081-tk7vn1v1	223	19	positioned	position	VBN
cord-278081-tk7vn1v1	223	20	nucleosomes	nucleosome	NNS
cord-278081-tk7vn1v1	223	21	(	(	-LRB-
cord-278081-tk7vn1v1	223	22	1	1	CD
cord-278081-tk7vn1v1	223	23	)	)	-RRB-
cord-278081-tk7vn1v1	223	24	.	.	.
cord-278081-tk7vn1v1	224	1	Reverse	reverse	JJ
cord-278081-tk7vn1v1	224	2	transcription	transcription	NN
cord-278081-tk7vn1v1	224	3	of	of	IN
cord-278081-tk7vn1v1	224	4	Alu	Alu	NNP
cord-278081-tk7vn1v1	224	5	elements	element	NNS
cord-278081-tk7vn1v1	224	6	could	could	MD
cord-278081-tk7vn1v1	224	7	be	be	VB
cord-278081-tk7vn1v1	224	8	particularly	particularly	RB
cord-278081-tk7vn1v1	224	9	consequential	consequential	JJ
cord-278081-tk7vn1v1	224	10	.	.	.
cord-278081-tk7vn1v1	225	1	Alu	Alu	NNP
cord-278081-tk7vn1v1	225	2	elements	element	NNS
cord-278081-tk7vn1v1	225	3	are	be	VBP
cord-278081-tk7vn1v1	225	4	rich	rich	JJ
cord-278081-tk7vn1v1	225	5	in	in	IN
cord-278081-tk7vn1v1	225	6	G	g	NN
cord-278081-tk7vn1v1	225	7	-	-	HYPH
cord-278081-tk7vn1v1	225	8	C	c	NN
cord-278081-tk7vn1v1	225	9	base	base	NN
cord-278081-tk7vn1v1	225	10	pairs	pair	NNS
cord-278081-tk7vn1v1	225	11	;	;	:
cord-278081-tk7vn1v1	225	12	therefore	therefore	RB
cord-278081-tk7vn1v1	225	13	,	,	,
cord-278081-tk7vn1v1	225	14	reverse	reverse	VB
cord-278081-tk7vn1v1	225	15	transcribed	transcribe	VBN
cord-278081-tk7vn1v1	225	16	Alu	Alu	NNP
cord-278081-tk7vn1v1	225	17	DNA	DNA	NNP
cord-278081-tk7vn1v1	225	18	would	would	MD
cord-278081-tk7vn1v1	225	19	require	require	VB
cord-278081-tk7vn1v1	225	20	significant	significant	JJ
cord-278081-tk7vn1v1	225	21	methylation	methylation	NN
cord-278081-tk7vn1v1	225	22	since	since	IN
cord-278081-tk7vn1v1	225	23	hypomethylated	hypomethylate	VBN
cord-278081-tk7vn1v1	225	24	DNA	DNA	NNP
cord-278081-tk7vn1v1	225	25	would	would	MD
cord-278081-tk7vn1v1	225	26	be	be	VB
cord-278081-tk7vn1v1	225	27	interpreted	interpret	VBN
cord-278081-tk7vn1v1	225	28	as	as	IN
cord-278081-tk7vn1v1	225	29	exogenous	exogenous	JJ
cord-278081-tk7vn1v1	225	30	.	.	.
cord-278081-tk7vn1v1	226	1	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	226	2	reverse	reverse	VB
cord-278081-tk7vn1v1	227	1	transcriptases	transcriptase	NNS
cord-278081-tk7vn1v1	227	2	preferentially	preferentially	RB
cord-278081-tk7vn1v1	227	3	reverse	reverse	VBP
cord-278081-tk7vn1v1	227	4	transcribe	transcribe	NN
cord-278081-tk7vn1v1	227	5	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	227	6	RNA	RNA	NNP
cord-278081-tk7vn1v1	227	7	at	at	IN
cord-278081-tk7vn1v1	227	8	a	a	DT
cord-278081-tk7vn1v1	227	9	rate	rate	NN
cord-278081-tk7vn1v1	227	10	of	of	IN
cord-278081-tk7vn1v1	227	11	1,000×	1,000×	CD
cord-278081-tk7vn1v1	227	12	and	and	CC
cord-278081-tk7vn1v1	227	13	Alu	Alu	NNP
cord-278081-tk7vn1v1	227	14	RNA	RNA	NNP
cord-278081-tk7vn1v1	227	15	at	at	IN
cord-278081-tk7vn1v1	227	16	a	a	DT
cord-278081-tk7vn1v1	227	17	rate	rate	NN
cord-278081-tk7vn1v1	227	18	of	of	IN
cord-278081-tk7vn1v1	227	19	300×	300×	CD
cord-278081-tk7vn1v1	227	20	in	in	IN
cord-278081-tk7vn1v1	227	21	comparison	comparison	NN
cord-278081-tk7vn1v1	227	22	to	to	IN
cord-278081-tk7vn1v1	227	23	other	other	JJ
cord-278081-tk7vn1v1	227	24	RNAs	rna	NNS
cord-278081-tk7vn1v1	227	25	(	(	-LRB-
cord-278081-tk7vn1v1	227	26	90	90	CD
cord-278081-tk7vn1v1	227	27	)	)	-RRB-
cord-278081-tk7vn1v1	227	28	.	.	.
cord-278081-tk7vn1v1	228	1	The	the	DT
cord-278081-tk7vn1v1	228	2	cell	cell	NN
cord-278081-tk7vn1v1	228	3	could	could	MD
cord-278081-tk7vn1v1	228	4	quickly	quickly	RB
cord-278081-tk7vn1v1	228	5	become	become	VB
cord-278081-tk7vn1v1	228	6	inundated	inundate	VBN
cord-278081-tk7vn1v1	228	7	with	with	IN
cord-278081-tk7vn1v1	228	8	hypomethylated	hypomethylate	VBN
cord-278081-tk7vn1v1	228	9	Alu	Alu	NNP
cord-278081-tk7vn1v1	228	10	DNA	DNA	NNP
cord-278081-tk7vn1v1	228	11	.	.	.
cord-278081-tk7vn1v1	229	1	Li	Li	NNP
cord-278081-tk7vn1v1	229	2	and	and	CC
cord-278081-tk7vn1v1	229	3	Steinman	Steinman	NNP
cord-278081-tk7vn1v1	229	4	reported	report	VBD
cord-278081-tk7vn1v1	229	5	a	a	DT
cord-278081-tk7vn1v1	229	6	high	high	JJ
cord-278081-tk7vn1v1	229	7	content	content	NN
cord-278081-tk7vn1v1	229	8	of	of	IN
cord-278081-tk7vn1v1	229	9	Alu	Alu	NNP
cord-278081-tk7vn1v1	229	10	DNA	DNA	NNP
cord-278081-tk7vn1v1	229	11	(	(	-LRB-
cord-278081-tk7vn1v1	229	12	up	up	IN
cord-278081-tk7vn1v1	229	13	to	to	TO
cord-278081-tk7vn1v1	229	14	55	55	CD
cord-278081-tk7vn1v1	229	15	%	%	NN
cord-278081-tk7vn1v1	229	16	)	)	-RRB-
cord-278081-tk7vn1v1	229	17	in	in	IN
cord-278081-tk7vn1v1	229	18	the	the	DT
cord-278081-tk7vn1v1	229	19	free	free	JJ
cord-278081-tk7vn1v1	229	20	DNA	dna	NN
cord-278081-tk7vn1v1	229	21	in	in	IN
cord-278081-tk7vn1v1	229	22	sera	sera	NNP
cord-278081-tk7vn1v1	229	23	of	of	IN
cord-278081-tk7vn1v1	229	24	lupus	lupus	NN
cord-278081-tk7vn1v1	229	25	patients	patient	NNS
cord-278081-tk7vn1v1	229	26	whereas	whereas	IN
cord-278081-tk7vn1v1	229	27	Alu	Alu	NNP
cord-278081-tk7vn1v1	229	28	elements	element	NNS
cord-278081-tk7vn1v1	229	29	only	only	RB
cord-278081-tk7vn1v1	229	30	account	account	VBP
cord-278081-tk7vn1v1	229	31	for	for	IN
cord-278081-tk7vn1v1	229	32	10.8	10.8	CD
cord-278081-tk7vn1v1	229	33	%	%	NN
cord-278081-tk7vn1v1	229	34	of	of	IN
cord-278081-tk7vn1v1	229	35	the	the	DT
cord-278081-tk7vn1v1	229	36	human	human	JJ
cord-278081-tk7vn1v1	229	37	genome	genome	NN
cord-278081-tk7vn1v1	229	38	(	(	-LRB-
cord-278081-tk7vn1v1	229	39	91	91	CD
cord-278081-tk7vn1v1	229	40	)	)	-RRB-
cord-278081-tk7vn1v1	229	41	.	.	.
cord-278081-tk7vn1v1	230	1	Those	those	DT
cord-278081-tk7vn1v1	230	2	authors	author	NNS
cord-278081-tk7vn1v1	230	3	suggested	suggest	VBD
cord-278081-tk7vn1v1	230	4	that	that	IN
cord-278081-tk7vn1v1	230	5	reverse	reverse	JJ
cord-278081-tk7vn1v1	230	6	transcription	transcription	NN
cord-278081-tk7vn1v1	230	7	could	could	MD
cord-278081-tk7vn1v1	230	8	be	be	VB
cord-278081-tk7vn1v1	230	9	a	a	DT
cord-278081-tk7vn1v1	230	10	possible	possible	JJ
cord-278081-tk7vn1v1	230	11	cause	cause	NN
cord-278081-tk7vn1v1	230	12	.	.	.
cord-278081-tk7vn1v1	231	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	231	2	proposed	propose	VBD
cord-278081-tk7vn1v1	231	3	that	that	IN
cord-278081-tk7vn1v1	231	4	fully	fully	RB
cord-278081-tk7vn1v1	231	5	functional	functional	JJ
cord-278081-tk7vn1v1	231	6	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	231	7	elements	element	NNS
cord-278081-tk7vn1v1	231	8	activated	activate	VBN
cord-278081-tk7vn1v1	231	9	from	from	IN
cord-278081-tk7vn1v1	231	10	disruption	disruption	NN
cord-278081-tk7vn1v1	231	11	of	of	IN
cord-278081-tk7vn1v1	231	12	the	the	DT
cord-278081-tk7vn1v1	231	13	X	x	NN
cord-278081-tk7vn1v1	231	14	chromosome	chromosome	NN
cord-278081-tk7vn1v1	231	15	could	could	MD
cord-278081-tk7vn1v1	231	16	be	be	VB
cord-278081-tk7vn1v1	231	17	involved	involve	VBN
cord-278081-tk7vn1v1	231	18	in	in	IN
cord-278081-tk7vn1v1	231	19	such	such	JJ
cord-278081-tk7vn1v1	231	20	reverse	reverse	JJ
cord-278081-tk7vn1v1	231	21	transcription	transcription	NN
cord-278081-tk7vn1v1	231	22	.	.	.
cord-278081-tk7vn1v1	232	1	eXpandinG	eXpandinG	NNP
cord-278081-tk7vn1v1	233	1	tHe	the	DT
cord-278081-tk7vn1v1	234	1	"	"	``
cord-278081-tk7vn1v1	234	2	X	X	NNP
cord-278081-tk7vn1v1	234	3	CHroMosoMe	CHroMosoMe	NNP
cord-278081-tk7vn1v1	234	4	-	-	HYPH
cord-278081-tk7vn1v1	234	5	nUCLeoLUs	nUCLeoLUs	NNP
cord-278081-tk7vn1v1	234	6	neXUs	neXUs	NNP
cord-278081-tk7vn1v1	234	7	"	"	``
cord-278081-tk7vn1v1	234	8	HypotHesis	HypotHesis	NNP
cord-278081-tk7vn1v1	234	9	:	:	:
cord-278081-tk7vn1v1	234	10	disrUption	disruption	NN
cord-278081-tk7vn1v1	234	11	oF	of	IN
cord-278081-tk7vn1v1	234	12	tHe	the	DT
cord-278081-tk7vn1v1	234	13	nUCLeoLUs	nucleolus	NN
cord-278081-tk7vn1v1	235	1	The	the	DT
cord-278081-tk7vn1v1	235	2	earlier	early	JJR
cord-278081-tk7vn1v1	235	3	version	version	NN
cord-278081-tk7vn1v1	235	4	of	of	IN
cord-278081-tk7vn1v1	235	5	the	the	DT
cord-278081-tk7vn1v1	235	6	"	"	``
cord-278081-tk7vn1v1	235	7	X	x	NN
cord-278081-tk7vn1v1	235	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	235	9	-	-	HYPH
cord-278081-tk7vn1v1	235	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	235	11	nexus	nexus	NN
cord-278081-tk7vn1v1	235	12	"	"	''
cord-278081-tk7vn1v1	235	13	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	235	14	suggested	suggest	VBD
cord-278081-tk7vn1v1	235	15	that	that	IN
cord-278081-tk7vn1v1	235	16	there	there	EX
cord-278081-tk7vn1v1	235	17	could	could	MD
cord-278081-tk7vn1v1	235	18	be	be	VB
cord-278081-tk7vn1v1	235	19	consequences	consequence	NNS
cord-278081-tk7vn1v1	235	20	from	from	IN
cord-278081-tk7vn1v1	235	21	expression	expression	NN
cord-278081-tk7vn1v1	235	22	of	of	IN
cord-278081-tk7vn1v1	235	23	previously	previously	RB
cord-278081-tk7vn1v1	235	24	sequestered	sequester	VBN
cord-278081-tk7vn1v1	235	25	Alu	Alu	NNP
cord-278081-tk7vn1v1	235	26	elements	element	NNS
cord-278081-tk7vn1v1	235	27	,	,	,
cord-278081-tk7vn1v1	235	28	particularly	particularly	RB
cord-278081-tk7vn1v1	235	29	from	from	IN
cord-278081-tk7vn1v1	235	30	the	the	DT
cord-278081-tk7vn1v1	235	31	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	235	32	of	of	IN
cord-278081-tk7vn1v1	235	33	the	the	DT
cord-278081-tk7vn1v1	235	34	X	x	NN
cord-278081-tk7vn1v1	235	35	chromosome	chromosome	NN
cord-278081-tk7vn1v1	235	36	short	short	JJ
cord-278081-tk7vn1v1	235	37	arm	arm	NN
cord-278081-tk7vn1v1	235	38	where	where	WRB
cord-278081-tk7vn1v1	235	39	there	there	EX
cord-278081-tk7vn1v1	235	40	is	be	VBZ
cord-278081-tk7vn1v1	235	41	an	an	DT
cord-278081-tk7vn1v1	235	42	exceptionally	exceptionally	RB
cord-278081-tk7vn1v1	235	43	high	high	JJ
cord-278081-tk7vn1v1	235	44	content	content	NN
cord-278081-tk7vn1v1	235	45	of	of	IN
cord-278081-tk7vn1v1	235	46	Alu	Alu	NNP
cord-278081-tk7vn1v1	235	47	elements	element	NNS
cord-278081-tk7vn1v1	235	48	(	(	-LRB-
cord-278081-tk7vn1v1	235	49	1	1	CD
cord-278081-tk7vn1v1	235	50	)	)	-RRB-
cord-278081-tk7vn1v1	235	51	.	.	.
cord-278081-tk7vn1v1	236	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	236	2	can	can	MD
cord-278081-tk7vn1v1	236	3	now	now	RB
cord-278081-tk7vn1v1	236	4	add	add	VB
cord-278081-tk7vn1v1	236	5	detail	detail	NN
cord-278081-tk7vn1v1	236	6	to	to	IN
cord-278081-tk7vn1v1	236	7	the	the	DT
cord-278081-tk7vn1v1	236	8	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	236	9	regarding	regard	VBG
cord-278081-tk7vn1v1	236	10	what	what	WDT
cord-278081-tk7vn1v1	236	11	consequences	consequence	NNS
cord-278081-tk7vn1v1	236	12	could	could	MD
cord-278081-tk7vn1v1	236	13	arise	arise	VB
cord-278081-tk7vn1v1	236	14	from	from	IN
cord-278081-tk7vn1v1	236	15	RNA	RNA	NNP
cord-278081-tk7vn1v1	236	16	pol	pol	NN
cord-278081-tk7vn1v1	236	17	III	iii	CD
cord-278081-tk7vn1v1	236	18	expression	expression	NN
cord-278081-tk7vn1v1	236	19	of	of	IN
cord-278081-tk7vn1v1	236	20	these	these	DT
cord-278081-tk7vn1v1	236	21	Alu	Alu	NNP
cord-278081-tk7vn1v1	236	22	elements	element	NNS
cord-278081-tk7vn1v1	236	23	.	.	.
cord-278081-tk7vn1v1	237	1	There	there	EX
cord-278081-tk7vn1v1	237	2	are	be	VBP
cord-278081-tk7vn1v1	237	3	over	over	IN
cord-278081-tk7vn1v1	237	4	1,000,000	1,000,000	CD
cord-278081-tk7vn1v1	237	5	Alu	Alu	NNP
cord-278081-tk7vn1v1	237	6	elements	element	NNS
cord-278081-tk7vn1v1	237	7	spread	spread	VBD
cord-278081-tk7vn1v1	237	8	throughout	throughout	IN
cord-278081-tk7vn1v1	237	9	the	the	DT
cord-278081-tk7vn1v1	237	10	human	human	JJ
cord-278081-tk7vn1v1	237	11	genome	genome	NN
cord-278081-tk7vn1v1	237	12	but	but	CC
cord-278081-tk7vn1v1	237	13	most	most	JJS
cord-278081-tk7vn1v1	237	14	are	be	VBP
cord-278081-tk7vn1v1	237	15	suppressed	suppress	VBN
cord-278081-tk7vn1v1	237	16	by	by	IN
cord-278081-tk7vn1v1	237	17	a	a	DT
cord-278081-tk7vn1v1	237	18	positioned	positioned	JJ
cord-278081-tk7vn1v1	237	19	nucleosome	nucleosome	NN
cord-278081-tk7vn1v1	237	20	.	.	.
cord-278081-tk7vn1v1	238	1	Displacement	displacement	NN
cord-278081-tk7vn1v1	238	2	of	of	IN
cord-278081-tk7vn1v1	238	3	the	the	DT
cord-278081-tk7vn1v1	238	4	nucleosome	nucleosome	NN
cord-278081-tk7vn1v1	238	5	could	could	MD
cord-278081-tk7vn1v1	238	6	open	open	VB
cord-278081-tk7vn1v1	238	7	the	the	DT
cord-278081-tk7vn1v1	238	8	Alu	Alu	NNP
cord-278081-tk7vn1v1	238	9	element	element	NN
cord-278081-tk7vn1v1	238	10	's	's	POS
cord-278081-tk7vn1v1	238	11	internal	internal	JJ
cord-278081-tk7vn1v1	238	12	RNA	RNA	NNP
cord-278081-tk7vn1v1	238	13	pol	pol	NN
cord-278081-tk7vn1v1	238	14	III	III	NNP
cord-278081-tk7vn1v1	238	15	transcription	transcription	NN
cord-278081-tk7vn1v1	238	16	start	start	NN
cord-278081-tk7vn1v1	238	17	site	site	NN
cord-278081-tk7vn1v1	238	18	.	.	.
cord-278081-tk7vn1v1	239	1	RNA	RNA	NNP
cord-278081-tk7vn1v1	239	2	pol	pol	NN
cord-278081-tk7vn1v1	239	3	III	III	NNP
cord-278081-tk7vn1v1	239	4	can	can	MD
cord-278081-tk7vn1v1	239	5	be	be	VB
cord-278081-tk7vn1v1	239	6	quite	quite	RB
cord-278081-tk7vn1v1	239	7	prolific	prolific	JJ
cord-278081-tk7vn1v1	239	8	since	since	IN
cord-278081-tk7vn1v1	239	9	it	-PRON-	PRP
cord-278081-tk7vn1v1	239	10	does	do	VBZ
cord-278081-tk7vn1v1	239	11	not	not	RB
cord-278081-tk7vn1v1	239	12	require	require	VB
cord-278081-tk7vn1v1	239	13	energy	energy	NN
cord-278081-tk7vn1v1	239	14	(	(	-LRB-
cord-278081-tk7vn1v1	239	15	ATP	ATP	NNP
cord-278081-tk7vn1v1	239	16	)	)	-RRB-
cord-278081-tk7vn1v1	239	17	,	,	,
cord-278081-tk7vn1v1	239	18	does	do	VBZ
cord-278081-tk7vn1v1	239	19	not	not	RB
cord-278081-tk7vn1v1	239	20	require	require	VB
cord-278081-tk7vn1v1	239	21	extensive	extensive	JJ
cord-278081-tk7vn1v1	239	22	assembly	assembly	NN
cord-278081-tk7vn1v1	239	23	of	of	IN
cord-278081-tk7vn1v1	239	24	transcription	transcription	NN
cord-278081-tk7vn1v1	239	25	factors	factor	NNS
cord-278081-tk7vn1v1	239	26	,	,	,
cord-278081-tk7vn1v1	239	27	can	can	MD
cord-278081-tk7vn1v1	239	28	initiate	initiate	VB
cord-278081-tk7vn1v1	239	29	from	from	IN
cord-278081-tk7vn1v1	239	30	the	the	DT
cord-278081-tk7vn1v1	239	31	intragenic	intragenic	JJ
cord-278081-tk7vn1v1	239	32	promoter	promoter	NN
cord-278081-tk7vn1v1	239	33	in	in	IN
cord-278081-tk7vn1v1	239	34	Alu	Alu	NNP
cord-278081-tk7vn1v1	239	35	elements	element	NNS
cord-278081-tk7vn1v1	239	36	,	,	,
cord-278081-tk7vn1v1	239	37	and	and	CC
cord-278081-tk7vn1v1	239	38	can	can	MD
cord-278081-tk7vn1v1	239	39	rapidly	rapidly	RB
cord-278081-tk7vn1v1	239	40	reinitiate	reinitiate	VB
cord-278081-tk7vn1v1	239	41	to	to	TO
cord-278081-tk7vn1v1	239	42	generate	generate	VB
cord-278081-tk7vn1v1	239	43	multiple	multiple	JJ
cord-278081-tk7vn1v1	239	44	transcripts	transcript	NNS
cord-278081-tk7vn1v1	239	45	.	.	.
cord-278081-tk7vn1v1	240	1	In	in	IN
cord-278081-tk7vn1v1	240	2	addition	addition	NN
cord-278081-tk7vn1v1	240	3	,	,	,
cord-278081-tk7vn1v1	240	4	since	since	IN
cord-278081-tk7vn1v1	240	5	Alu	Alu	NNP
cord-278081-tk7vn1v1	240	6	elements	element	NNS
cord-278081-tk7vn1v1	240	7	average	average	JJ
cord-278081-tk7vn1v1	240	8	only	only	RB
cord-278081-tk7vn1v1	240	9	300	300	CD
cord-278081-tk7vn1v1	240	10	bp	bp	NNP
cord-278081-tk7vn1v1	240	11	and	and	CC
cord-278081-tk7vn1v1	240	12	the	the	DT
cord-278081-tk7vn1v1	240	13	intragenic	intragenic	NNP
cord-278081-tk7vn1v1	240	14	promoter	promoter	NN
cord-278081-tk7vn1v1	240	15	requires	require	VBZ
cord-278081-tk7vn1v1	240	16	only	only	RB
cord-278081-tk7vn1v1	240	17	about	about	RB
cord-278081-tk7vn1v1	240	18	70	70	CD
cord-278081-tk7vn1v1	240	19	bp	bp	NN
cord-278081-tk7vn1v1	240	20	for	for	IN
cord-278081-tk7vn1v1	240	21	transcription	transcription	NN
cord-278081-tk7vn1v1	240	22	factor	factor	NN
cord-278081-tk7vn1v1	241	1	binding	binding	NN
cord-278081-tk7vn1v1	241	2	,	,	,
cord-278081-tk7vn1v1	241	3	displacement	displacement	NN
cord-278081-tk7vn1v1	241	4	of	of	IN
cord-278081-tk7vn1v1	241	5	only	only	RB
cord-278081-tk7vn1v1	241	6	one	one	CD
cord-278081-tk7vn1v1	241	7	nucleosome	nucleosome	NN
cord-278081-tk7vn1v1	241	8	would	would	MD
cord-278081-tk7vn1v1	241	9	be	be	VB
cord-278081-tk7vn1v1	241	10	all	all	PDT
cord-278081-tk7vn1v1	241	11	the	the	DT
cord-278081-tk7vn1v1	241	12	opening	opening	NN
cord-278081-tk7vn1v1	241	13	needed	need	VBN
cord-278081-tk7vn1v1	241	14	.	.	.
cord-278081-tk7vn1v1	242	1	The	the	DT
cord-278081-tk7vn1v1	242	2	abundance	abundance	NN
cord-278081-tk7vn1v1	242	3	of	of	IN
cord-278081-tk7vn1v1	242	4	RNA	rna	NN
cord-278081-tk7vn1v1	242	5	pol	pol	NN
cord-278081-tk7vn1v1	242	6	III	III	NNP
cord-278081-tk7vn1v1	242	7	typically	typically	RB
cord-278081-tk7vn1v1	242	8	found	find	VBN
cord-278081-tk7vn1v1	242	9	near	near	IN
cord-278081-tk7vn1v1	242	10	the	the	DT
cord-278081-tk7vn1v1	242	11	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	242	12	,	,	,
cord-278081-tk7vn1v1	242	13	particularly	particularly	RB
cord-278081-tk7vn1v1	242	14	the	the	DT
cord-278081-tk7vn1v1	242	15	perinucleolar	perinucleolar	NNP
cord-278081-tk7vn1v1	242	16	compartment	compartment	NNP
cord-278081-tk7vn1v1	242	17	,	,	,
cord-278081-tk7vn1v1	242	18	could	could	MD
cord-278081-tk7vn1v1	242	19	rapidly	rapidly	RB
cord-278081-tk7vn1v1	242	20	generate	generate	VB
cord-278081-tk7vn1v1	242	21	thousands	thousand	NNS
cord-278081-tk7vn1v1	242	22	of	of	IN
cord-278081-tk7vn1v1	242	23	Alu	Alu	NNP
cord-278081-tk7vn1v1	242	24	RNAs	rna	NNS
cord-278081-tk7vn1v1	242	25	if	if	IN
cord-278081-tk7vn1v1	242	26	there	there	EX
cord-278081-tk7vn1v1	242	27	were	be	VBD
cord-278081-tk7vn1v1	242	28	a	a	DT
cord-278081-tk7vn1v1	242	29	disruptive	disruptive	JJ
cord-278081-tk7vn1v1	242	30	event	event	NN
cord-278081-tk7vn1v1	242	31	,	,	,
cord-278081-tk7vn1v1	242	32	such	such	JJ
cord-278081-tk7vn1v1	242	33	as	as	IN
cord-278081-tk7vn1v1	242	34	encroachment	encroachment	NN
cord-278081-tk7vn1v1	242	35	of	of	IN
cord-278081-tk7vn1v1	242	36	the	the	DT
cord-278081-tk7vn1v1	242	37	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	242	38	into	into	IN
cord-278081-tk7vn1v1	242	39	the	the	DT
cord-278081-tk7vn1v1	242	40	Barr	Barr	NNP
cord-278081-tk7vn1v1	242	41	body	body	NN
cord-278081-tk7vn1v1	242	42	.	.	.
cord-278081-tk7vn1v1	243	1	Especially	especially	RB
cord-278081-tk7vn1v1	243	2	vulnerable	vulnerable	JJ
cord-278081-tk7vn1v1	243	3	is	be	VBZ
cord-278081-tk7vn1v1	243	4	the	the	DT
cord-278081-tk7vn1v1	243	5	dense	dense	JJ
cord-278081-tk7vn1v1	243	6	cluster	cluster	NN
cord-278081-tk7vn1v1	243	7	of	of	IN
cord-278081-tk7vn1v1	243	8	Alu	Alu	NNP
cord-278081-tk7vn1v1	243	9	elements	element	NNS
cord-278081-tk7vn1v1	243	10	in	in	IN
cord-278081-tk7vn1v1	243	11	the	the	DT
cord-278081-tk7vn1v1	243	12	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	243	13	region	region	NN
cord-278081-tk7vn1v1	243	14	near	near	IN
cord-278081-tk7vn1v1	243	15	the	the	DT
cord-278081-tk7vn1v1	243	16	surface	surface	NN
cord-278081-tk7vn1v1	243	17	of	of	IN
cord-278081-tk7vn1v1	243	18	the	the	DT
cord-278081-tk7vn1v1	243	19	Barr	Barr	NNP
cord-278081-tk7vn1v1	243	20	body	body	NN
cord-278081-tk7vn1v1	243	21	.	.	.
cord-278081-tk7vn1v1	244	1	Whereas	whereas	IN
cord-278081-tk7vn1v1	244	2	Alu	Alu	NNP
cord-278081-tk7vn1v1	244	3	elements	element	NNS
cord-278081-tk7vn1v1	244	4	comprise	comprise	VBP
cord-278081-tk7vn1v1	244	5	10.8	10.8	CD
cord-278081-tk7vn1v1	244	6	%	%	NN
cord-278081-tk7vn1v1	244	7	of	of	IN
cord-278081-tk7vn1v1	244	8	the	the	DT
cord-278081-tk7vn1v1	244	9	human	human	JJ
cord-278081-tk7vn1v1	244	10	genome	genome	NN
cord-278081-tk7vn1v1	244	11	,	,	,
cord-278081-tk7vn1v1	244	12	they	-PRON-	PRP
cord-278081-tk7vn1v1	244	13	are	be	VBP
cord-278081-tk7vn1v1	244	14	at	at	IN
cord-278081-tk7vn1v1	244	15	only	only	RB
cord-278081-tk7vn1v1	244	16	8	8	CD
cord-278081-tk7vn1v1	244	17	%	%	NN
cord-278081-tk7vn1v1	244	18	in	in	IN
cord-278081-tk7vn1v1	244	19	the	the	DT
cord-278081-tk7vn1v1	244	20	X	x	NN
cord-278081-tk7vn1v1	244	21	chromosome	chromosome	NN
cord-278081-tk7vn1v1	244	22	.	.	.
cord-278081-tk7vn1v1	245	1	However	however	RB
cord-278081-tk7vn1v1	245	2	,	,	,
cord-278081-tk7vn1v1	245	3	Alu	Alu	NNP
cord-278081-tk7vn1v1	245	4	elements	element	NNS
cord-278081-tk7vn1v1	245	5	account	account	VBP
cord-278081-tk7vn1v1	245	6	for	for	IN
cord-278081-tk7vn1v1	245	7	28.8	28.8	CD
cord-278081-tk7vn1v1	245	8	%	%	NN
cord-278081-tk7vn1v1	245	9	of	of	IN
cord-278081-tk7vn1v1	245	10	the	the	DT
cord-278081-tk7vn1v1	245	11	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	245	12	region	region	NN
cord-278081-tk7vn1v1	245	13	and	and	CC
cord-278081-tk7vn1v1	245	14	19	19	CD
cord-278081-tk7vn1v1	245	15	%	%	NN
cord-278081-tk7vn1v1	245	16	of	of	IN
cord-278081-tk7vn1v1	245	17	the	the	DT
cord-278081-tk7vn1v1	245	18	adjacent	adjacent	JJ
cord-278081-tk7vn1v1	245	19	S5	S5	NNP
cord-278081-tk7vn1v1	245	20	region	region	NN
cord-278081-tk7vn1v1	245	21	(	(	-LRB-
cord-278081-tk7vn1v1	245	22	46	46	CD
cord-278081-tk7vn1v1	245	23	)	)	-RRB-
cord-278081-tk7vn1v1	245	24	.	.	.
cord-278081-tk7vn1v1	246	1	Since	since	IN
cord-278081-tk7vn1v1	246	2	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	246	3	has	have	VBZ
cord-278081-tk7vn1v1	246	4	approximately	approximately	RB
cord-278081-tk7vn1v1	246	5	2.5	2.5	CD
cord-278081-tk7vn1v1	246	6	million	million	CD
cord-278081-tk7vn1v1	246	7	base	base	NN
cord-278081-tk7vn1v1	246	8	pairs	pair	NNS
cord-278081-tk7vn1v1	246	9	,	,	,
cord-278081-tk7vn1v1	246	10	there	there	EX
cord-278081-tk7vn1v1	246	11	are	be	VBP
cord-278081-tk7vn1v1	246	12	estimated	estimate	VBN
cord-278081-tk7vn1v1	246	13	to	to	TO
cord-278081-tk7vn1v1	246	14	be	be	VB
cord-278081-tk7vn1v1	246	15	more	more	JJR
cord-278081-tk7vn1v1	246	16	than	than	IN
cord-278081-tk7vn1v1	246	17	2,500	2,500	CD
cord-278081-tk7vn1v1	246	18	Alu	Alu	NNP
cord-278081-tk7vn1v1	246	19	elements	element	NNS
cord-278081-tk7vn1v1	246	20	in	in	IN
cord-278081-tk7vn1v1	246	21	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	246	22	that	that	WDT
cord-278081-tk7vn1v1	246	23	could	could	MD
cord-278081-tk7vn1v1	246	24	potentially	potentially	RB
cord-278081-tk7vn1v1	246	25	flood	flood	VB
cord-278081-tk7vn1v1	246	26	the	the	DT
cord-278081-tk7vn1v1	246	27	nucleus	nucleus	NN
cord-278081-tk7vn1v1	246	28	and	and	CC
cord-278081-tk7vn1v1	246	29	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	246	30	with	with	IN
cord-278081-tk7vn1v1	246	31	Alu	Alu	NNP
cord-278081-tk7vn1v1	246	32	RNA	RNA	NNP
cord-278081-tk7vn1v1	246	33	transcripts	transcript	NNS
cord-278081-tk7vn1v1	246	34	(	(	-LRB-
cord-278081-tk7vn1v1	246	35	Figure	figure	NN
cord-278081-tk7vn1v1	246	36	4A	4a	CD
cord-278081-tk7vn1v1	246	37	)	)	-RRB-
cord-278081-tk7vn1v1	246	38	.	.	.
cord-278081-tk7vn1v1	247	1	Contrast	contrast	VB
cord-278081-tk7vn1v1	247	2	this	this	DT
cord-278081-tk7vn1v1	247	3	with	with	IN
cord-278081-tk7vn1v1	247	4	the	the	DT
cord-278081-tk7vn1v1	247	5	approximately	approximately	RB
cord-278081-tk7vn1v1	247	6	200	200	CD
cord-278081-tk7vn1v1	247	7	active	active	JJ
cord-278081-tk7vn1v1	247	8	ribosomal	ribosomal	NN
cord-278081-tk7vn1v1	247	9	RNA	RNA	NNP
cord-278081-tk7vn1v1	247	10	genes	gene	NNS
cord-278081-tk7vn1v1	247	11	in	in	IN
cord-278081-tk7vn1v1	247	12	the	the	DT
cord-278081-tk7vn1v1	247	13	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	247	14	.	.	.
cord-278081-tk7vn1v1	248	1	The	the	DT
cord-278081-tk7vn1v1	248	2	Alu	Alu	NNP
cord-278081-tk7vn1v1	248	3	RNAs	rna	NNS
cord-278081-tk7vn1v1	248	4	could	could	MD
cord-278081-tk7vn1v1	248	5	interfere	interfere	VB
cord-278081-tk7vn1v1	248	6	with	with	IN
cord-278081-tk7vn1v1	248	7	assembly	assembly	NN
cord-278081-tk7vn1v1	248	8	of	of	IN
cord-278081-tk7vn1v1	248	9	the	the	DT
cord-278081-tk7vn1v1	248	10	SRP	SRP	NNP
cord-278081-tk7vn1v1	248	11	which	which	WDT
cord-278081-tk7vn1v1	248	12	contains	contain	VBZ
cord-278081-tk7vn1v1	248	13	an	an	DT
cord-278081-tk7vn1v1	248	14	Alu	Alu	NNP
cord-278081-tk7vn1v1	248	15	domain	domain	NN
cord-278081-tk7vn1v1	248	16	that	that	WDT
cord-278081-tk7vn1v1	248	17	binds	bind	VBZ
cord-278081-tk7vn1v1	248	18	SRP	SRP	NNP
cord-278081-tk7vn1v1	248	19	9/14	9/14	CD
cord-278081-tk7vn1v1	248	20	heterodimers	heterodimer	NNS
cord-278081-tk7vn1v1	248	21	(	(	-LRB-
cord-278081-tk7vn1v1	248	22	72	72	CD
cord-278081-tk7vn1v1	248	23	)	)	-RRB-
cord-278081-tk7vn1v1	248	24	.	.	.
cord-278081-tk7vn1v1	249	1	Free	Free	NNP
cord-278081-tk7vn1v1	249	2	Alu	Alu	NNP
cord-278081-tk7vn1v1	249	3	RNA	RNA	NNP
cord-278081-tk7vn1v1	249	4	could	could	MD
cord-278081-tk7vn1v1	249	5	compete	compete	VB
cord-278081-tk7vn1v1	249	6	in	in	IN
cord-278081-tk7vn1v1	249	7	binding	bind	VBG
cord-278081-tk7vn1v1	249	8	the	the	DT
cord-278081-tk7vn1v1	249	9	SRP	SRP	NNP
cord-278081-tk7vn1v1	249	10	9/14	9/14	CD
cord-278081-tk7vn1v1	249	11	leaving	leave	VBG
cord-278081-tk7vn1v1	249	12	incomplete	incomplete	JJ
cord-278081-tk7vn1v1	249	13	SRPs	srp	NNS
cord-278081-tk7vn1v1	249	14	that	that	WDT
cord-278081-tk7vn1v1	249	15	can	can	MD
cord-278081-tk7vn1v1	249	16	not	not	RB
cord-278081-tk7vn1v1	249	17	halt	halt	VB
cord-278081-tk7vn1v1	249	18	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	249	19	activity	activity	NN
cord-278081-tk7vn1v1	249	20	in	in	IN
cord-278081-tk7vn1v1	249	21	the	the	DT
cord-278081-tk7vn1v1	249	22	cytoplasm	cytoplasm	NN
cord-278081-tk7vn1v1	249	23	when	when	WRB
cord-278081-tk7vn1v1	249	24	needed	need	VBN
cord-278081-tk7vn1v1	249	25	during	during	IN
cord-278081-tk7vn1v1	249	26	synthesis	synthesis	NN
cord-278081-tk7vn1v1	249	27	of	of	IN
cord-278081-tk7vn1v1	249	28	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	249	29	targeted	target	VBN
cord-278081-tk7vn1v1	249	30	proteins	protein	NNS
cord-278081-tk7vn1v1	249	31	.	.	.
cord-278081-tk7vn1v1	250	1	This	this	DT
cord-278081-tk7vn1v1	250	2	could	could	MD
cord-278081-tk7vn1v1	250	3	lead	lead	VB
cord-278081-tk7vn1v1	250	4	to	to	IN
cord-278081-tk7vn1v1	250	5	improper	improper	JJ
cord-278081-tk7vn1v1	250	6	modifications	modification	NNS
cord-278081-tk7vn1v1	250	7	(	(	-LRB-
cord-278081-tk7vn1v1	250	8	e.g.	e.g.	RB
cord-278081-tk7vn1v1	250	9	,	,	,
cord-278081-tk7vn1v1	250	10	transglutamination	transglutamination	NN
cord-278081-tk7vn1v1	250	11	)	)	-RRB-
cord-278081-tk7vn1v1	250	12	and	and	CC
cord-278081-tk7vn1v1	250	13	localization	localization	NN
cord-278081-tk7vn1v1	250	14	of	of	IN
cord-278081-tk7vn1v1	250	15	proteins	protein	NNS
cord-278081-tk7vn1v1	250	16	.	.	.
cord-278081-tk7vn1v1	251	1	And	and	CC
cord-278081-tk7vn1v1	251	2	,	,	,
cord-278081-tk7vn1v1	251	3	opening	opening	NN
cord-278081-tk7vn1v1	251	4	of	of	IN
cord-278081-tk7vn1v1	251	5	the	the	DT
cord-278081-tk7vn1v1	251	6	Alu	Alu	NNP
cord-278081-tk7vn1v1	251	7	elements	element	NNS
cord-278081-tk7vn1v1	251	8	,	,	,
cord-278081-tk7vn1v1	251	9	which	which	WDT
cord-278081-tk7vn1v1	251	10	have	have	VBP
cord-278081-tk7vn1v1	251	11	extensive	extensive	JJ
cord-278081-tk7vn1v1	251	12	intra	intra	JJ
cord-278081-tk7vn1v1	251	13	-	-	JJ
cord-278081-tk7vn1v1	251	14	strand	strand	JJ
cord-278081-tk7vn1v1	251	15	matching	matching	NN
cord-278081-tk7vn1v1	251	16	sequences	sequence	NNS
cord-278081-tk7vn1v1	251	17	,	,	,
cord-278081-tk7vn1v1	251	18	could	could	MD
cord-278081-tk7vn1v1	251	19	also	also	RB
cord-278081-tk7vn1v1	251	20	facilitate	facilitate	VB
cord-278081-tk7vn1v1	251	21	formation	formation	NN
cord-278081-tk7vn1v1	251	22	of	of	IN
cord-278081-tk7vn1v1	251	23	cruciforms	cruciform	NNS
cord-278081-tk7vn1v1	251	24	in	in	IN
cord-278081-tk7vn1v1	251	25	the	the	DT
cord-278081-tk7vn1v1	251	26	DNA	dna	NN
cord-278081-tk7vn1v1	251	27	which	which	WDT
cord-278081-tk7vn1v1	251	28	could	could	MD
cord-278081-tk7vn1v1	251	29	be	be	VB
cord-278081-tk7vn1v1	251	30	stabilized	stabilize	VBN
cord-278081-tk7vn1v1	251	31	by	by	IN
cord-278081-tk7vn1v1	251	32	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	251	33	.	.	.
cord-278081-tk7vn1v1	252	1	These	these	DT
cord-278081-tk7vn1v1	252	2	cruciforms	cruciform	NNS
cord-278081-tk7vn1v1	252	3	could	could	MD
cord-278081-tk7vn1v1	252	4	be	be	VB
cord-278081-tk7vn1v1	252	5	interpreted	interpret	VBN
cord-278081-tk7vn1v1	252	6	as	as	IN
cord-278081-tk7vn1v1	252	7	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	252	8	by	by	IN
cord-278081-tk7vn1v1	252	9	the	the	DT
cord-278081-tk7vn1v1	252	10	immune	immune	JJ
cord-278081-tk7vn1v1	252	11	system	system	NN
cord-278081-tk7vn1v1	252	12	.	.	.
cord-278081-tk7vn1v1	253	1	Perhaps	perhaps	RB
cord-278081-tk7vn1v1	253	2	,	,	,
cord-278081-tk7vn1v1	253	3	the	the	DT
cord-278081-tk7vn1v1	253	4	greatest	great	JJS
cord-278081-tk7vn1v1	253	5	danger	danger	NN
cord-278081-tk7vn1v1	253	6	from	from	IN
cord-278081-tk7vn1v1	253	7	expression	expression	NN
cord-278081-tk7vn1v1	253	8	of	of	IN
cord-278081-tk7vn1v1	253	9	Alu	Alu	NNP
cord-278081-tk7vn1v1	253	10	elements	element	NNS
cord-278081-tk7vn1v1	253	11	from	from	IN
cord-278081-tk7vn1v1	253	12	the	the	DT
cord-278081-tk7vn1v1	253	13	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	253	14	Barr	Barr	NNP
cord-278081-tk7vn1v1	253	15	body	body	NN
cord-278081-tk7vn1v1	253	16	is	be	VBZ
cord-278081-tk7vn1v1	253	17	deduced	deduce	VBN
cord-278081-tk7vn1v1	253	18	from	from	IN
cord-278081-tk7vn1v1	253	19	the	the	DT
cord-278081-tk7vn1v1	253	20	work	work	NN
cord-278081-tk7vn1v1	253	21	of	of	IN
cord-278081-tk7vn1v1	253	22	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	253	23	-	-	HYPH
cord-278081-tk7vn1v1	253	24	Herger	Herger	NNP
cord-278081-tk7vn1v1	253	25	and	and	CC
cord-278081-tk7vn1v1	253	26	colleagues	colleague	NNS
cord-278081-tk7vn1v1	253	27	mentioned	mention	VBD
cord-278081-tk7vn1v1	253	28	previously	previously	RB
cord-278081-tk7vn1v1	253	29	(	(	-LRB-
cord-278081-tk7vn1v1	253	30	59	59	CD
cord-278081-tk7vn1v1	253	31	)	)	-RRB-
cord-278081-tk7vn1v1	253	32	.	.	.
cord-278081-tk7vn1v1	254	1	An	an	DT
cord-278081-tk7vn1v1	254	2	abundance	abundance	NN
cord-278081-tk7vn1v1	254	3	of	of	IN
cord-278081-tk7vn1v1	254	4	RNA	rna	NN
cord-278081-tk7vn1v1	254	5	pol	pol	NN
cord-278081-tk7vn1v1	254	6	III	III	NNP
cord-278081-tk7vn1v1	254	7	Alu	Alu	NNP
cord-278081-tk7vn1v1	254	8	transcripts	transcript	NNS
cord-278081-tk7vn1v1	254	9	from	from	IN
cord-278081-tk7vn1v1	254	10	the	the	DT
cord-278081-tk7vn1v1	254	11	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	254	12	Barr	Barr	NNP
cord-278081-tk7vn1v1	254	13	body	body	NN
cord-278081-tk7vn1v1	254	14	could	could	MD
cord-278081-tk7vn1v1	254	15	compete	compete	VB
cord-278081-tk7vn1v1	254	16	with	with	IN
cord-278081-tk7vn1v1	254	17	or	or	CC
cord-278081-tk7vn1v1	254	18	lead	lead	VB
cord-278081-tk7vn1v1	254	19	to	to	IN
cord-278081-tk7vn1v1	254	20	degradation	degradation	NN
cord-278081-tk7vn1v1	254	21	of	of	IN
cord-278081-tk7vn1v1	254	22	the	the	DT
cord-278081-tk7vn1v1	254	23	RNA	RNA	NNP
cord-278081-tk7vn1v1	254	24	pol	pol	NN
cord-278081-tk7vn1v1	254	25	II	II	NNP
cord-278081-tk7vn1v1	255	1	intronic	intronic	NNP
cord-278081-tk7vn1v1	255	2	Alu	Alu	NNP
cord-278081-tk7vn1v1	255	3	RNA	RNA	NNP
cord-278081-tk7vn1v1	256	1	that	that	IN
cord-278081-tk7vn1v1	256	2	,	,	,
cord-278081-tk7vn1v1	256	3	along	along	IN
cord-278081-tk7vn1v1	256	4	with	with	IN
cord-278081-tk7vn1v1	256	5	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	256	6	and	and	CC
cord-278081-tk7vn1v1	256	7	nucleophosmin	nucleophosmin	NNP
cord-278081-tk7vn1v1	256	8	,	,	,
cord-278081-tk7vn1v1	256	9	provides	provide	VBZ
cord-278081-tk7vn1v1	256	10	structural	structural	JJ
cord-278081-tk7vn1v1	256	11	integrity	integrity	NN
cord-278081-tk7vn1v1	256	12	for	for	IN
cord-278081-tk7vn1v1	256	13	the	the	DT
cord-278081-tk7vn1v1	256	14	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	256	15	.	.	.
cord-278081-tk7vn1v1	257	1	This	this	DT
cord-278081-tk7vn1v1	257	2	would	would	MD
cord-278081-tk7vn1v1	257	3	lead	lead	VB
cord-278081-tk7vn1v1	257	4	to	to	IN
cord-278081-tk7vn1v1	257	5	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	257	6	of	of	IN
cord-278081-tk7vn1v1	257	7	the	the	DT
cord-278081-tk7vn1v1	257	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	257	9	into	into	IN
cord-278081-tk7vn1v1	257	10	inefficient	inefficient	JJ
cord-278081-tk7vn1v1	257	11	subunits	subunit	NNS
cord-278081-tk7vn1v1	257	12	(	(	-LRB-
cord-278081-tk7vn1v1	257	13	Figure	figure	NN
cord-278081-tk7vn1v1	257	14	4B	4b	CD
cord-278081-tk7vn1v1	257	15	)	)	-RRB-
cord-278081-tk7vn1v1	257	16	.	.	.
cord-278081-tk7vn1v1	258	1	These	these	DT
cord-278081-tk7vn1v1	258	2	nucleolar	nucleolar	NN
cord-278081-tk7vn1v1	258	3	-	-	HYPH
cord-278081-tk7vn1v1	258	4	derived	derive	VBN
cord-278081-tk7vn1v1	258	5	subunits	subunit	NNS
cord-278081-tk7vn1v1	258	6	could	could	MD
cord-278081-tk7vn1v1	258	7	have	have	VB
cord-278081-tk7vn1v1	258	8	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	258	9	levels	level	NNS
cord-278081-tk7vn1v1	258	10	of	of	IN
cord-278081-tk7vn1v1	258	11	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	258	12	and	and	CC
cord-278081-tk7vn1v1	258	13	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	258	14	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	258	15	that	that	WDT
cord-278081-tk7vn1v1	258	16	can	can	MD
cord-278081-tk7vn1v1	258	17	not	not	RB
cord-278081-tk7vn1v1	258	18	properly	properly	RB
cord-278081-tk7vn1v1	258	19	fold	fold	VB
cord-278081-tk7vn1v1	258	20	RNA	RNA	NNP
cord-278081-tk7vn1v1	258	21	and	and	CC
cord-278081-tk7vn1v1	258	22	assemble	assemble	VB
cord-278081-tk7vn1v1	258	23	RNPs	rnp	NNS
cord-278081-tk7vn1v1	258	24	.	.	.
cord-278081-tk7vn1v1	259	1	In	in	IN
cord-278081-tk7vn1v1	259	2	fact	fact	NN
cord-278081-tk7vn1v1	259	3	,	,	,
cord-278081-tk7vn1v1	259	4	the	the	DT
cord-278081-tk7vn1v1	259	5	needed	need	VBN
cord-278081-tk7vn1v1	259	6	components	component	NNS
cord-278081-tk7vn1v1	259	7	for	for	IN
cord-278081-tk7vn1v1	259	8	assembly	assembly	NN
cord-278081-tk7vn1v1	259	9	of	of	IN
cord-278081-tk7vn1v1	259	10	an	an	DT
cord-278081-tk7vn1v1	259	11	RNP	RNP	NNP
cord-278081-tk7vn1v1	259	12	like	like	IN
cord-278081-tk7vn1v1	259	13	the	the	DT
cord-278081-tk7vn1v1	259	14	ribosome	ribosome	NN
cord-278081-tk7vn1v1	259	15	may	may	MD
cord-278081-tk7vn1v1	259	16	be	be	VB
cord-278081-tk7vn1v1	259	17	unequally	unequally	RB
cord-278081-tk7vn1v1	259	18	distributed	distribute	VBN
cord-278081-tk7vn1v1	259	19	among	among	IN
cord-278081-tk7vn1v1	259	20	the	the	DT
cord-278081-tk7vn1v1	259	21	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	259	22	fragments	fragment	NNS
cord-278081-tk7vn1v1	259	23	preventing	prevent	VBG
cord-278081-tk7vn1v1	259	24	complete	complete	JJ
cord-278081-tk7vn1v1	259	25	assembly	assembly	NN
cord-278081-tk7vn1v1	259	26	.	.	.
cord-278081-tk7vn1v1	260	1	And	and	CC
cord-278081-tk7vn1v1	260	2	there	there	EX
cord-278081-tk7vn1v1	260	3	could	could	MD
cord-278081-tk7vn1v1	260	4	be	be	VB
cord-278081-tk7vn1v1	260	5	viral	viral	JJ
cord-278081-tk7vn1v1	260	6	proteins	protein	NNS
cord-278081-tk7vn1v1	260	7	and	and	CC
cord-278081-tk7vn1v1	260	8	RNAs	rna	NNS
cord-278081-tk7vn1v1	260	9	competing	compete	VBG
cord-278081-tk7vn1v1	260	10	to	to	TO
cord-278081-tk7vn1v1	260	11	join	join	VB
cord-278081-tk7vn1v1	260	12	RNP	RNP	NNP
cord-278081-tk7vn1v1	260	13	assemblies	assembly	NNS
cord-278081-tk7vn1v1	260	14	.	.	.
cord-278081-tk7vn1v1	261	1	The	the	DT
cord-278081-tk7vn1v1	261	2	RNPs	rnp	NNS
cord-278081-tk7vn1v1	261	3	and	and	CC
cord-278081-tk7vn1v1	261	4	partial	partial	JJ
cord-278081-tk7vn1v1	261	5	assemblies	assembly	NNS
cord-278081-tk7vn1v1	261	6	could	could	MD
cord-278081-tk7vn1v1	261	7	be	be	VB
cord-278081-tk7vn1v1	261	8	stabilized	stabilize	VBN
cord-278081-tk7vn1v1	261	9	in	in	IN
cord-278081-tk7vn1v1	261	10	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	261	11	conformations	conformation	NNS
cord-278081-tk7vn1v1	261	12	and	and	CC
cord-278081-tk7vn1v1	261	13	associations	association	NNS
cord-278081-tk7vn1v1	261	14	by	by	IN
cord-278081-tk7vn1v1	261	15	the	the	DT
cord-278081-tk7vn1v1	261	16	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	261	17	and	and	CC
cord-278081-tk7vn1v1	261	18	become	become	VB
cord-278081-tk7vn1v1	261	19	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	261	20	when	when	WRB
cord-278081-tk7vn1v1	261	21	released	release	VBN
cord-278081-tk7vn1v1	261	22	from	from	IN
cord-278081-tk7vn1v1	261	23	the	the	DT
cord-278081-tk7vn1v1	261	24	cell	cell	NN
cord-278081-tk7vn1v1	261	25	.	.	.
cord-278081-tk7vn1v1	262	1	Such	such	JJ
cord-278081-tk7vn1v1	262	2	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	262	3	exposure	exposure	NN
cord-278081-tk7vn1v1	262	4	could	could	MD
cord-278081-tk7vn1v1	262	5	occur	occur	VB
cord-278081-tk7vn1v1	262	6	by	by	IN
cord-278081-tk7vn1v1	262	7	blebbing	blebbe	VBG
cord-278081-tk7vn1v1	262	8	and	and	CC
cord-278081-tk7vn1v1	262	9	microparticle	microparticle	NNP
cord-278081-tk7vn1v1	262	10	release	release	NNP
cord-278081-tk7vn1v1	262	11	as	as	IN
cord-278081-tk7vn1v1	262	12	the	the	DT
cord-278081-tk7vn1v1	262	13	cell	cell	NN
cord-278081-tk7vn1v1	262	14	enters	enter	VBZ
cord-278081-tk7vn1v1	262	15	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	262	16	,	,	,
cord-278081-tk7vn1v1	262	17	NETosis	netosis	NN
cord-278081-tk7vn1v1	262	18	or	or	CC
cord-278081-tk7vn1v1	262	19	other	other	JJ
cord-278081-tk7vn1v1	262	20	forms	form	NNS
cord-278081-tk7vn1v1	262	21	of	of	IN
cord-278081-tk7vn1v1	262	22	termination	termination	NN
cord-278081-tk7vn1v1	262	23	(	(	-LRB-
cord-278081-tk7vn1v1	262	24	92	92	CD
cord-278081-tk7vn1v1	262	25	)	)	-RRB-
cord-278081-tk7vn1v1	262	26	.	.	.
cord-278081-tk7vn1v1	263	1	With	with	IN
cord-278081-tk7vn1v1	263	2	a	a	DT
cord-278081-tk7vn1v1	263	3	loss	loss	NN
cord-278081-tk7vn1v1	263	4	of	of	IN
cord-278081-tk7vn1v1	263	5	integrity	integrity	NN
cord-278081-tk7vn1v1	263	6	of	of	IN
cord-278081-tk7vn1v1	263	7	the	the	DT
cord-278081-tk7vn1v1	263	8	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	263	9	and	and	CC
cord-278081-tk7vn1v1	263	10	expression	expression	NN
cord-278081-tk7vn1v1	263	11	of	of	IN
cord-278081-tk7vn1v1	263	12	viral	viral	JJ
cord-278081-tk7vn1v1	263	13	components	component	NNS
cord-278081-tk7vn1v1	263	14	,	,	,
cord-278081-tk7vn1v1	263	15	some	some	DT
cord-278081-tk7vn1v1	263	16	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	263	17	material	material	NN
cord-278081-tk7vn1v1	263	18	could	could	MD
cord-278081-tk7vn1v1	263	19	be	be	VB
cord-278081-tk7vn1v1	263	20	displayed	display	VBN
cord-278081-tk7vn1v1	263	21	on	on	IN
cord-278081-tk7vn1v1	263	22	the	the	DT
cord-278081-tk7vn1v1	263	23	cell	cell	NN
cord-278081-tk7vn1v1	263	24	surface	surface	NN
cord-278081-tk7vn1v1	263	25	,	,	,
cord-278081-tk7vn1v1	263	26	such	such	JJ
cord-278081-tk7vn1v1	263	27	as	as	IN
cord-278081-tk7vn1v1	263	28	the	the	DT
cord-278081-tk7vn1v1	263	29	La	La	NNP
cord-278081-tk7vn1v1	263	30	protein	protein	NN
cord-278081-tk7vn1v1	263	31	(	(	-LRB-
cord-278081-tk7vn1v1	263	32	81	81	CD
cord-278081-tk7vn1v1	263	33	)	)	-RRB-
cord-278081-tk7vn1v1	263	34	.	.	.
cord-278081-tk7vn1v1	264	1	In	in	IN
cord-278081-tk7vn1v1	264	2	addition	addition	NN
cord-278081-tk7vn1v1	264	3	,	,	,
cord-278081-tk7vn1v1	264	4	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	264	5	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	264	6	could	could	MD
cord-278081-tk7vn1v1	264	7	lead	lead	VB
cord-278081-tk7vn1v1	264	8	to	to	IN
cord-278081-tk7vn1v1	264	9	loss	loss	NN
cord-278081-tk7vn1v1	264	10	of	of	IN
cord-278081-tk7vn1v1	264	11	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	264	12	control	control	NN
cord-278081-tk7vn1v1	264	13	of	of	IN
cord-278081-tk7vn1v1	264	14	cell	cell	NN
cord-278081-tk7vn1v1	264	15	cycling	cycling	NN
cord-278081-tk7vn1v1	264	16	,	,	,
cord-278081-tk7vn1v1	264	17	such	such	JJ
cord-278081-tk7vn1v1	264	18	as	as	IN
cord-278081-tk7vn1v1	264	19	assembly	assembly	NN
cord-278081-tk7vn1v1	264	20	of	of	IN
cord-278081-tk7vn1v1	264	21	centromeres	centromere	NNS
cord-278081-tk7vn1v1	264	22	.	.	.
cord-278081-tk7vn1v1	265	1	Another	another	DT
cord-278081-tk7vn1v1	265	2	problem	problem	NN
cord-278081-tk7vn1v1	265	3	that	that	WDT
cord-278081-tk7vn1v1	265	4	could	could	MD
cord-278081-tk7vn1v1	265	5	arise	arise	VB
cord-278081-tk7vn1v1	265	6	is	be	VBZ
cord-278081-tk7vn1v1	265	7	involvement	involvement	NN
cord-278081-tk7vn1v1	265	8	of	of	IN
cord-278081-tk7vn1v1	265	9	cyclic	cyclic	JJ
cord-278081-tk7vn1v1	265	10	GMP	GMP	NNP
cord-278081-tk7vn1v1	265	11	-	-	HYPH
cord-278081-tk7vn1v1	265	12	AMP	AMP	NNP
cord-278081-tk7vn1v1	265	13	synthase	synthase	NN
cord-278081-tk7vn1v1	265	14	(	(	-LRB-
cord-278081-tk7vn1v1	265	15	cGAS	cGAS	NNP
cord-278081-tk7vn1v1	265	16	)	)	-RRB-
cord-278081-tk7vn1v1	265	17	which	which	WDT
cord-278081-tk7vn1v1	265	18	detects	detect	VBZ
cord-278081-tk7vn1v1	265	19	cytosolic	cytosolic	JJ
cord-278081-tk7vn1v1	265	20	DNA	dna	NN
cord-278081-tk7vn1v1	265	21	.	.	.
cord-278081-tk7vn1v1	266	1	This	this	DT
cord-278081-tk7vn1v1	266	2	includes	include	VBZ
cord-278081-tk7vn1v1	266	3	detection	detection	NN
cord-278081-tk7vn1v1	266	4	of	of	IN
cord-278081-tk7vn1v1	266	5	micronuclei	micronuclei	NNP
cord-278081-tk7vn1v1	266	6	that	that	WDT
cord-278081-tk7vn1v1	266	7	contain	contain	VBP
cord-278081-tk7vn1v1	266	8	DNA	DNA	NNP
cord-278081-tk7vn1v1	266	9	from	from	IN
cord-278081-tk7vn1v1	266	10	a	a	DT
cord-278081-tk7vn1v1	266	11	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	266	12	nucleus	nucleus	NN
cord-278081-tk7vn1v1	266	13	or	or	CC
cord-278081-tk7vn1v1	266	14	from	from	IN
cord-278081-tk7vn1v1	266	15	DNA	dna	NN
cord-278081-tk7vn1v1	266	16	damage	damage	NN
cord-278081-tk7vn1v1	266	17	(	(	-LRB-
cord-278081-tk7vn1v1	266	18	93	93	CD
cord-278081-tk7vn1v1	266	19	)	)	-RRB-
cord-278081-tk7vn1v1	266	20	.	.	.
cord-278081-tk7vn1v1	267	1	Fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	267	2	of	of	IN
cord-278081-tk7vn1v1	267	3	the	the	DT
cord-278081-tk7vn1v1	267	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	267	5	,	,	,
cord-278081-tk7vn1v1	267	6	as	as	IN
cord-278081-tk7vn1v1	267	7	described	describe	VBN
cord-278081-tk7vn1v1	267	8	above	above	RB
cord-278081-tk7vn1v1	267	9	,	,	,
cord-278081-tk7vn1v1	267	10	could	could	MD
cord-278081-tk7vn1v1	267	11	potentially	potentially	RB
cord-278081-tk7vn1v1	267	12	generate	generate	VB
cord-278081-tk7vn1v1	267	13	such	such	JJ
cord-278081-tk7vn1v1	267	14	micronuclei	micronuclei	NN
cord-278081-tk7vn1v1	267	15	,	,	,
cord-278081-tk7vn1v1	267	16	especially	especially	RB
cord-278081-tk7vn1v1	267	17	when	when	WRB
cord-278081-tk7vn1v1	267	18	centromere	centromere	NNP
cord-278081-tk7vn1v1	267	19	assembly	assembly	NN
cord-278081-tk7vn1v1	267	20	and	and	CC
cord-278081-tk7vn1v1	267	21	functioning	functioning	NN
cord-278081-tk7vn1v1	267	22	are	be	VBP
cord-278081-tk7vn1v1	267	23	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	267	24	or	or	CC
cord-278081-tk7vn1v1	267	25	when	when	WRB
cord-278081-tk7vn1v1	267	26	there	there	EX
cord-278081-tk7vn1v1	267	27	are	be	VBP
cord-278081-tk7vn1v1	267	28	lagging	lag	VBG
cord-278081-tk7vn1v1	267	29	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	267	30	during	during	IN
cord-278081-tk7vn1v1	267	31	mitotic	mitotic	JJ
cord-278081-tk7vn1v1	267	32	segregation	segregation	NN
cord-278081-tk7vn1v1	267	33	of	of	IN
cord-278081-tk7vn1v1	267	34	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	267	35	.	.	.
cord-278081-tk7vn1v1	268	1	The	the	DT
cord-278081-tk7vn1v1	268	2	appearance	appearance	NN
cord-278081-tk7vn1v1	268	3	of	of	IN
cord-278081-tk7vn1v1	268	4	hypomethylated	hypomethylate	VBN
cord-278081-tk7vn1v1	268	5	reverse	reverse	NN
cord-278081-tk7vn1v1	268	6	transcribed	transcribe	VBN
cord-278081-tk7vn1v1	268	7	Alu	Alu	NNP
cord-278081-tk7vn1v1	268	8	DNA	DNA	NNP
cord-278081-tk7vn1v1	268	9	in	in	IN
cord-278081-tk7vn1v1	268	10	the	the	DT
cord-278081-tk7vn1v1	268	11	cytosol	cytosol	NN
cord-278081-tk7vn1v1	268	12	,	,	,
cord-278081-tk7vn1v1	268	13	possibly	possibly	RB
cord-278081-tk7vn1v1	268	14	originating	originate	VBG
cord-278081-tk7vn1v1	268	15	from	from	IN
cord-278081-tk7vn1v1	268	16	X	x	NN
cord-278081-tk7vn1v1	268	17	-	-	HYPH
cord-278081-tk7vn1v1	268	18	linked	link	VBN
cord-278081-tk7vn1v1	268	19	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	268	20	reverse	reverse	VB
cord-278081-tk7vn1v1	268	21	transcription	transcription	NN
cord-278081-tk7vn1v1	268	22	of	of	IN
cord-278081-tk7vn1v1	268	23	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	268	24	Alu	Alu	NNP
cord-278081-tk7vn1v1	268	25	element	element	NN
cord-278081-tk7vn1v1	268	26	RNA	RNA	NNP
cord-278081-tk7vn1v1	268	27	,	,	,
cord-278081-tk7vn1v1	268	28	could	could	MD
cord-278081-tk7vn1v1	268	29	also	also	RB
cord-278081-tk7vn1v1	268	30	trigger	trigger	VB
cord-278081-tk7vn1v1	268	31	the	the	DT
cord-278081-tk7vn1v1	268	32	cGAS	cgas	JJ
cord-278081-tk7vn1v1	268	33	-	-	HYPH
cord-278081-tk7vn1v1	268	34	STING	sting	NN
cord-278081-tk7vn1v1	268	35	pathway	pathway	NN
cord-278081-tk7vn1v1	268	36	.	.	.
cord-278081-tk7vn1v1	269	1	Formation	formation	NN
cord-278081-tk7vn1v1	269	2	of	of	IN
cord-278081-tk7vn1v1	269	3	cyclic	cyclic	JJ
cord-278081-tk7vn1v1	269	4	GMP	GMP	NNP
cord-278081-tk7vn1v1	269	5	-	-	HYPH
cord-278081-tk7vn1v1	269	6	AMP	AMP	NNP
cord-278081-tk7vn1v1	269	7	(	(	-LRB-
cord-278081-tk7vn1v1	269	8	cGAMP	cGAMP	NNP
cord-278081-tk7vn1v1	269	9	)	)	-RRB-
cord-278081-tk7vn1v1	269	10	can	can	MD
cord-278081-tk7vn1v1	269	11	trigger	trigger	VB
cord-278081-tk7vn1v1	269	12	activation	activation	NN
cord-278081-tk7vn1v1	269	13	of	of	IN
cord-278081-tk7vn1v1	269	14	the	the	DT
cord-278081-tk7vn1v1	269	15	Stimulator	Stimulator	NNP
cord-278081-tk7vn1v1	269	16	of	of	IN
cord-278081-tk7vn1v1	269	17	Interferon	Interferon	NNP
cord-278081-tk7vn1v1	269	18	Genes	Genes	NNP
cord-278081-tk7vn1v1	269	19	(	(	-LRB-
cord-278081-tk7vn1v1	269	20	STING	sting	NN
cord-278081-tk7vn1v1	269	21	)	)	-RRB-
cord-278081-tk7vn1v1	269	22	protein	protein	NN
cord-278081-tk7vn1v1	269	23	which	which	WDT
cord-278081-tk7vn1v1	269	24	induces	induce	VBZ
cord-278081-tk7vn1v1	269	25	transcription	transcription	NN
cord-278081-tk7vn1v1	269	26	of	of	IN
cord-278081-tk7vn1v1	269	27	interferon	interferon	NN
cord-278081-tk7vn1v1	269	28	β	β	NNP
cord-278081-tk7vn1v1	269	29	(	(	-LRB-
cord-278081-tk7vn1v1	269	30	IFNβ	IFNβ	NNP
cord-278081-tk7vn1v1	269	31	)	)	-RRB-
cord-278081-tk7vn1v1	269	32	as	as	IN
cord-278081-tk7vn1v1	269	33	part	part	NN
cord-278081-tk7vn1v1	269	34	of	of	IN
cord-278081-tk7vn1v1	269	35	the	the	DT
cord-278081-tk7vn1v1	269	36	innate	innate	JJ
cord-278081-tk7vn1v1	269	37	immune	immune	JJ
cord-278081-tk7vn1v1	269	38	response	response	NN
cord-278081-tk7vn1v1	269	39	in	in	IN
cord-278081-tk7vn1v1	269	40	antiviral	antiviral	JJ
cord-278081-tk7vn1v1	269	41	,	,	,
cord-278081-tk7vn1v1	269	42	antibacterial	antibacterial	JJ
cord-278081-tk7vn1v1	269	43	,	,	,
cord-278081-tk7vn1v1	269	44	and	and	CC
cord-278081-tk7vn1v1	269	45	anticancer	anticancer	JJ
cord-278081-tk7vn1v1	269	46	activity	activity	NN
cord-278081-tk7vn1v1	269	47	and	and	CC
cord-278081-tk7vn1v1	269	48	is	be	VBZ
cord-278081-tk7vn1v1	269	49	suspected	suspect	VBN
cord-278081-tk7vn1v1	269	50	of	of	IN
cord-278081-tk7vn1v1	269	51	involvement	involvement	NN
cord-278081-tk7vn1v1	269	52	in	in	IN
cord-278081-tk7vn1v1	269	53	autoinflammatory	autoinflammatory	JJ
cord-278081-tk7vn1v1	269	54	and	and	CC
cord-278081-tk7vn1v1	269	55	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	269	56	diseases	disease	NNS
cord-278081-tk7vn1v1	269	57	(	(	-LRB-
cord-278081-tk7vn1v1	269	58	94	94	CD
cord-278081-tk7vn1v1	269	59	)	)	-RRB-
cord-278081-tk7vn1v1	269	60	.	.	.
cord-278081-tk7vn1v1	270	1	Therefore	therefore	RB
cord-278081-tk7vn1v1	270	2	,	,	,
cord-278081-tk7vn1v1	270	3	the	the	DT
cord-278081-tk7vn1v1	270	4	original	original	JJ
cord-278081-tk7vn1v1	270	5	"	"	``
cord-278081-tk7vn1v1	270	6	X	x	NN
cord-278081-tk7vn1v1	270	7	chromosome	chromosome	NN
cord-278081-tk7vn1v1	270	8	-	-	HYPH
cord-278081-tk7vn1v1	270	9	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	270	10	nexus	nexus	NN
cord-278081-tk7vn1v1	270	11	"	"	''
cord-278081-tk7vn1v1	270	12	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	270	13	,	,	,
cord-278081-tk7vn1v1	270	14	which	which	WDT
cord-278081-tk7vn1v1	270	15	explained	explain	VBD
cord-278081-tk7vn1v1	270	16	how	how	WRB
cord-278081-tk7vn1v1	270	17	the	the	DT
cord-278081-tk7vn1v1	270	18	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	270	19	could	could	MD
cord-278081-tk7vn1v1	270	20	disrupt	disrupt	VB
cord-278081-tk7vn1v1	270	21	the	the	DT
cord-278081-tk7vn1v1	270	22	inactive	inactive	JJ
cord-278081-tk7vn1v1	270	23	X	x	NN
cord-278081-tk7vn1v1	270	24	chromosome	chromosome	NN
cord-278081-tk7vn1v1	270	25	,	,	,
cord-278081-tk7vn1v1	270	26	can	can	MD
cord-278081-tk7vn1v1	270	27	now	now	RB
cord-278081-tk7vn1v1	270	28	be	be	VB
cord-278081-tk7vn1v1	270	29	expanded	expand	VBN
cord-278081-tk7vn1v1	270	30	to	to	TO
cord-278081-tk7vn1v1	270	31	include	include	VB
cord-278081-tk7vn1v1	270	32	disruption	disruption	NN
cord-278081-tk7vn1v1	270	33	of	of	IN
cord-278081-tk7vn1v1	270	34	the	the	DT
cord-278081-tk7vn1v1	270	35	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	270	36	by	by	IN
cord-278081-tk7vn1v1	270	37	X	x	NN
cord-278081-tk7vn1v1	270	38	-	-	HYPH
cord-278081-tk7vn1v1	270	39	linked	link	VBN
cord-278081-tk7vn1v1	270	40	Alu	Alu	NNP
cord-278081-tk7vn1v1	270	41	RNA	RNA	NNP
cord-278081-tk7vn1v1	270	42	transcripts	transcript	NNS
cord-278081-tk7vn1v1	270	43	that	that	WDT
cord-278081-tk7vn1v1	270	44	lead	lead	VBP
cord-278081-tk7vn1v1	270	45	to	to	IN
cord-278081-tk7vn1v1	270	46	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	270	47	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	270	48	and	and	CC
cord-278081-tk7vn1v1	270	49	generation	generation	NN
cord-278081-tk7vn1v1	270	50	of	of	IN
cord-278081-tk7vn1v1	270	51	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	270	52	material	material	NN
cord-278081-tk7vn1v1	270	53	.	.	.
cord-278081-tk7vn1v1	271	1	tHe	the	DT
cord-278081-tk7vn1v1	272	1	"	"	``
cord-278081-tk7vn1v1	272	2	X	X	NNP
cord-278081-tk7vn1v1	272	3	CHroMosoMe	CHroMosoMe	NNP
cord-278081-tk7vn1v1	272	4	-	-	HYPH
cord-278081-tk7vn1v1	272	5	nUCLeoLUs	nUCLeoLUs	NNP
cord-278081-tk7vn1v1	272	6	neXUs	neXUs	NNP
cord-278081-tk7vn1v1	272	7	"	"	``
cord-278081-tk7vn1v1	272	8	HypotHesis	HypotHesis	NNP
cord-278081-tk7vn1v1	272	9	in	in	IN
cord-278081-tk7vn1v1	272	10	reLation	reLation	NNP
cord-278081-tk7vn1v1	272	11	to	to	IN
cord-278081-tk7vn1v1	272	12	otHer	other	NN
cord-278081-tk7vn1v1	272	13	diseases	disease	NNS
cord-278081-tk7vn1v1	273	1	The	the	DT
cord-278081-tk7vn1v1	273	2	"	"	``
cord-278081-tk7vn1v1	273	3	X	x	NN
cord-278081-tk7vn1v1	273	4	chromosome	chromosome	NN
cord-278081-tk7vn1v1	273	5	-	-	HYPH
cord-278081-tk7vn1v1	273	6	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	273	7	nexus	nexus	NN
cord-278081-tk7vn1v1	273	8	"	"	''
cord-278081-tk7vn1v1	273	9	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	273	10	was	be	VBD
cord-278081-tk7vn1v1	273	11	developed	develop	VBN
cord-278081-tk7vn1v1	273	12	primarily	primarily	RB
cord-278081-tk7vn1v1	273	13	with	with	IN
cord-278081-tk7vn1v1	273	14	SLE	SLE	NNP
cord-278081-tk7vn1v1	273	15	in	in	IN
cord-278081-tk7vn1v1	273	16	mind	mind	NN
cord-278081-tk7vn1v1	274	1	but	but	CC
cord-278081-tk7vn1v1	274	2	it	-PRON-	PRP
cord-278081-tk7vn1v1	274	3	could	could	MD
cord-278081-tk7vn1v1	274	4	be	be	VB
cord-278081-tk7vn1v1	274	5	involved	involve	VBN
cord-278081-tk7vn1v1	274	6	in	in	IN
cord-278081-tk7vn1v1	274	7	many	many	JJ
cord-278081-tk7vn1v1	274	8	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	274	9	diseases	disease	NNS
cord-278081-tk7vn1v1	274	10	.	.	.
cord-278081-tk7vn1v1	275	1	The	the	DT
cord-278081-tk7vn1v1	275	2	mechanism	mechanism	NN
cord-278081-tk7vn1v1	275	3	could	could	MD
cord-278081-tk7vn1v1	275	4	have	have	VB
cord-278081-tk7vn1v1	275	5	differing	differ	VBG
cord-278081-tk7vn1v1	275	6	effects	effect	NNS
cord-278081-tk7vn1v1	275	7	due	due	IN
cord-278081-tk7vn1v1	275	8	to	to	IN
cord-278081-tk7vn1v1	275	9	the	the	DT
cord-278081-tk7vn1v1	275	10	cell	cell	NN
cord-278081-tk7vn1v1	275	11	types	type	NNS
cord-278081-tk7vn1v1	275	12	and	and	CC
cord-278081-tk7vn1v1	275	13	locations	location	NNS
cord-278081-tk7vn1v1	275	14	involved	involve	VBN
cord-278081-tk7vn1v1	275	15	.	.	.
cord-278081-tk7vn1v1	276	1	For	for	IN
cord-278081-tk7vn1v1	276	2	example	example	NN
cord-278081-tk7vn1v1	276	3	,	,	,
cord-278081-tk7vn1v1	276	4	RA	RA	NNP
cord-278081-tk7vn1v1	276	5	and	and	CC
cord-278081-tk7vn1v1	276	6	SLE	SLE	NNP
cord-278081-tk7vn1v1	276	7	can	can	MD
cord-278081-tk7vn1v1	276	8	have	have	VB
cord-278081-tk7vn1v1	276	9	some	some	DT
cord-278081-tk7vn1v1	276	10	of	of	IN
cord-278081-tk7vn1v1	276	11	the	the	DT
cord-278081-tk7vn1v1	276	12	same	same	JJ
cord-278081-tk7vn1v1	276	13	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	276	14	targeted	target	VBN
cord-278081-tk7vn1v1	276	15	,	,	,
cord-278081-tk7vn1v1	276	16	FiGUre	FiGUre	NNP
cord-278081-tk7vn1v1	276	17	4	4	CD
cord-278081-tk7vn1v1	276	18	|	|	NNP
cord-278081-tk7vn1v1	276	19	Autoantigens	Autoantigens	NNP
cord-278081-tk7vn1v1	276	20	generated	generate	VBN
cord-278081-tk7vn1v1	276	21	by	by	IN
cord-278081-tk7vn1v1	276	22	disruption	disruption	NN
cord-278081-tk7vn1v1	276	23	of	of	IN
cord-278081-tk7vn1v1	276	24	the	the	DT
cord-278081-tk7vn1v1	276	25	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	276	26	.	.	.
cord-278081-tk7vn1v1	277	1	(	(	-LRB-
cord-278081-tk7vn1v1	277	2	a	a	LS
cord-278081-tk7vn1v1	277	3	)	)	-RRB-
cord-278081-tk7vn1v1	278	1	The	the	DT
cord-278081-tk7vn1v1	278	2	original	original	JJ
cord-278081-tk7vn1v1	278	3	version	version	NN
cord-278081-tk7vn1v1	278	4	of	of	IN
cord-278081-tk7vn1v1	278	5	the	the	DT
cord-278081-tk7vn1v1	278	6	"	"	``
cord-278081-tk7vn1v1	278	7	inactive	inactive	JJ
cord-278081-tk7vn1v1	278	8	X	x	NN
cord-278081-tk7vn1v1	278	9	chromosome	chromosome	NN
cord-278081-tk7vn1v1	278	10	and	and	CC
cord-278081-tk7vn1v1	278	11	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	278	12	nexus	nexus	NN
cord-278081-tk7vn1v1	278	13	"	"	''
cord-278081-tk7vn1v1	278	14	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	278	15	proposed	propose	VBD
cord-278081-tk7vn1v1	278	16	that	that	IN
cord-278081-tk7vn1v1	278	17	there	there	EX
cord-278081-tk7vn1v1	278	18	is	be	VBZ
cord-278081-tk7vn1v1	278	19	disruption	disruption	NN
cord-278081-tk7vn1v1	278	20	of	of	IN
cord-278081-tk7vn1v1	278	21	the	the	DT
cord-278081-tk7vn1v1	278	22	inactive	inactive	JJ
cord-278081-tk7vn1v1	278	23	X	X	NNS
cord-278081-tk7vn1v1	278	24	by	by	IN
cord-278081-tk7vn1v1	278	25	the	the	DT
cord-278081-tk7vn1v1	278	26	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	278	27	due	due	IN
cord-278081-tk7vn1v1	278	28	to	to	IN
cord-278081-tk7vn1v1	278	29	an	an	DT
cord-278081-tk7vn1v1	278	30	extraordinary	extraordinary	JJ
cord-278081-tk7vn1v1	278	31	expansion	expansion	NN
cord-278081-tk7vn1v1	278	32	of	of	IN
cord-278081-tk7vn1v1	278	33	the	the	DT
cord-278081-tk7vn1v1	278	34	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	278	35	under	under	IN
cord-278081-tk7vn1v1	278	36	stress	stress	NN
cord-278081-tk7vn1v1	278	37	(	(	-LRB-
cord-278081-tk7vn1v1	278	38	Figure	figure	NN
cord-278081-tk7vn1v1	278	39	2b	2b	CD
cord-278081-tk7vn1v1	278	40	)	)	-RRB-
cord-278081-tk7vn1v1	278	41	.	.	.
cord-278081-tk7vn1v1	279	1	This	this	DT
cord-278081-tk7vn1v1	279	2	disruption	disruption	NN
cord-278081-tk7vn1v1	279	3	could	could	MD
cord-278081-tk7vn1v1	279	4	open	open	VB
cord-278081-tk7vn1v1	279	5	previously	previously	RB
cord-278081-tk7vn1v1	279	6	sequestered	sequester	VBN
cord-278081-tk7vn1v1	279	7	DNA	dna	NN
cord-278081-tk7vn1v1	279	8	,	,	,
cord-278081-tk7vn1v1	279	9	especially	especially	RB
cord-278081-tk7vn1v1	279	10	Alu	Alu	NNP
cord-278081-tk7vn1v1	279	11	sequences	sequence	NNS
cord-278081-tk7vn1v1	279	12	and	and	CC
cord-278081-tk7vn1v1	279	13	genes	gene	NNS
cord-278081-tk7vn1v1	279	14	in	in	IN
cord-278081-tk7vn1v1	279	15	the	the	DT
cord-278081-tk7vn1v1	279	16	short	short	JJ
cord-278081-tk7vn1v1	279	17	arm	arm	NN
cord-278081-tk7vn1v1	279	18	of	of	IN
cord-278081-tk7vn1v1	279	19	the	the	DT
cord-278081-tk7vn1v1	279	20	Xi	Xi	NNP
cord-278081-tk7vn1v1	279	21	that	that	WDT
cord-278081-tk7vn1v1	279	22	are	be	VBP
cord-278081-tk7vn1v1	279	23	located	locate	VBN
cord-278081-tk7vn1v1	279	24	in	in	IN
cord-278081-tk7vn1v1	279	25	the	the	DT
cord-278081-tk7vn1v1	279	26	euchromatic	euchromatic	JJ
cord-278081-tk7vn1v1	279	27	-	-	HYPH
cord-278081-tk7vn1v1	279	28	like	like	JJ
cord-278081-tk7vn1v1	279	29	surface	surface	NN
cord-278081-tk7vn1v1	279	30	layer	layer	NN
cord-278081-tk7vn1v1	279	31	of	of	IN
cord-278081-tk7vn1v1	279	32	the	the	DT
cord-278081-tk7vn1v1	279	33	Xi	Xi	NNP
cord-278081-tk7vn1v1	279	34	(	(	-LRB-
cord-278081-tk7vn1v1	279	35	1	1	CD
cord-278081-tk7vn1v1	279	36	)	)	-RRB-
cord-278081-tk7vn1v1	279	37	.	.	.
cord-278081-tk7vn1v1	280	1	Now	now	RB
cord-278081-tk7vn1v1	280	2	,	,	,
cord-278081-tk7vn1v1	280	3	based	base	VBN
cord-278081-tk7vn1v1	280	4	on	on	IN
cord-278081-tk7vn1v1	280	5	the	the	DT
cord-278081-tk7vn1v1	280	6	work	work	NN
cord-278081-tk7vn1v1	280	7	by	by	IN
cord-278081-tk7vn1v1	280	8	Caudron	Caudron	NNP
cord-278081-tk7vn1v1	280	9	-	-	HYPH
cord-278081-tk7vn1v1	280	10	Herger	Herger	NNP
cord-278081-tk7vn1v1	280	11	and	and	CC
cord-278081-tk7vn1v1	280	12	colleagues	colleague	NNS
cord-278081-tk7vn1v1	280	13	(	(	-LRB-
cord-278081-tk7vn1v1	280	14	59	59	CD
cord-278081-tk7vn1v1	280	15	)	)	-RRB-
cord-278081-tk7vn1v1	280	16	,	,	,
cord-278081-tk7vn1v1	280	17	we	-PRON-	PRP
cord-278081-tk7vn1v1	280	18	can	can	MD
cord-278081-tk7vn1v1	280	19	propose	propose	VB
cord-278081-tk7vn1v1	280	20	additions	addition	NNS
cord-278081-tk7vn1v1	280	21	to	to	IN
cord-278081-tk7vn1v1	280	22	the	the	DT
cord-278081-tk7vn1v1	280	23	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	280	24	,	,	,
cord-278081-tk7vn1v1	280	25	that	that	IN
cord-278081-tk7vn1v1	280	26	X	x	NN
cord-278081-tk7vn1v1	280	27	-	-	HYPH
cord-278081-tk7vn1v1	280	28	linked	link	VBN
cord-278081-tk7vn1v1	280	29	Alu	Alu	NNP
cord-278081-tk7vn1v1	280	30	transcripts	transcript	NNS
cord-278081-tk7vn1v1	280	31	generated	generate	VBN
cord-278081-tk7vn1v1	280	32	by	by	IN
cord-278081-tk7vn1v1	280	33	the	the	DT
cord-278081-tk7vn1v1	280	34	abundant	abundant	JJ
cord-278081-tk7vn1v1	280	35	RNA	RNA	NNP
cord-278081-tk7vn1v1	280	36	pol	pol	NN
cord-278081-tk7vn1v1	280	37	III	III	NNP
cord-278081-tk7vn1v1	280	38	near	near	IN
cord-278081-tk7vn1v1	280	39	the	the	DT
cord-278081-tk7vn1v1	280	40	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	280	41	can	can	MD
cord-278081-tk7vn1v1	280	42	disrupt	disrupt	VB
cord-278081-tk7vn1v1	280	43	the	the	DT
cord-278081-tk7vn1v1	280	44	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	280	45	-	-	HYPH
cord-278081-tk7vn1v1	280	46	RNA	RNA	NNP
cord-278081-tk7vn1v1	280	47	pol	pol	NN
cord-278081-tk7vn1v1	280	48	II	II	NNP
cord-278081-tk7vn1v1	280	49	intronic	intronic	NNP
cord-278081-tk7vn1v1	280	50	Alu	Alu	NNP
cord-278081-tk7vn1v1	280	51	complexes	complex	NNS
cord-278081-tk7vn1v1	280	52	,	,	,
cord-278081-tk7vn1v1	280	53	either	either	CC
cord-278081-tk7vn1v1	280	54	by	by	IN
cord-278081-tk7vn1v1	280	55	Dicer	Dicer	NNP
cord-278081-tk7vn1v1	280	56	degradation	degradation	NN
cord-278081-tk7vn1v1	280	57	or	or	CC
cord-278081-tk7vn1v1	280	58	by	by	IN
cord-278081-tk7vn1v1	280	59	direct	direct	JJ
cord-278081-tk7vn1v1	280	60	competition	competition	NN
cord-278081-tk7vn1v1	280	61	between	between	IN
cord-278081-tk7vn1v1	280	62	the	the	DT
cord-278081-tk7vn1v1	280	63	RNA	RNA	NNP
cord-278081-tk7vn1v1	280	64	pol	pol	NN
cord-278081-tk7vn1v1	280	65	III	III	NNP
cord-278081-tk7vn1v1	280	66	Alu	Alu	NNP
cord-278081-tk7vn1v1	280	67	transcripts	transcript	NNS
cord-278081-tk7vn1v1	280	68	and	and	CC
cord-278081-tk7vn1v1	280	69	the	the	DT
cord-278081-tk7vn1v1	280	70	intronic	intronic	NNP
cord-278081-tk7vn1v1	280	71	Alu	Alu	NNP
cord-278081-tk7vn1v1	280	72	sequences	sequence	NNS
cord-278081-tk7vn1v1	280	73	.	.	.
cord-278081-tk7vn1v1	281	1	(	(	-LRB-
cord-278081-tk7vn1v1	281	2	b	b	NN
cord-278081-tk7vn1v1	281	3	)	)	-RRB-
cord-278081-tk7vn1v1	282	1	The	the	DT
cord-278081-tk7vn1v1	282	2	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	282	3	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	282	4	of	of	IN
cord-278081-tk7vn1v1	282	5	the	the	DT
cord-278081-tk7vn1v1	282	6	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	282	7	could	could	MD
cord-278081-tk7vn1v1	282	8	result	result	VB
cord-278081-tk7vn1v1	282	9	in	in	IN
cord-278081-tk7vn1v1	282	10	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	282	11	fragments	fragment	NNS
cord-278081-tk7vn1v1	282	12	that	that	WDT
cord-278081-tk7vn1v1	282	13	contain	contain	VBP
cord-278081-tk7vn1v1	282	14	conformationally	conformationally	RB
cord-278081-tk7vn1v1	282	15	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	282	16	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	282	17	structures	structure	NNS
cord-278081-tk7vn1v1	282	18	due	due	JJ
cord-278081-tk7vn1v1	282	19	to	to	IN
cord-278081-tk7vn1v1	282	20	improperly	improperly	RB
cord-278081-tk7vn1v1	282	21	folded	fold	VBN
cord-278081-tk7vn1v1	282	22	RNAs	rna	NNS
cord-278081-tk7vn1v1	282	23	or	or	CC
cord-278081-tk7vn1v1	282	24	improperly	improperly	RB
cord-278081-tk7vn1v1	282	25	assembled	assemble	VBN
cord-278081-tk7vn1v1	282	26	ribonucleoprotein	ribonucleoprotein	NN
cord-278081-tk7vn1v1	282	27	complexes	complex	NNS
cord-278081-tk7vn1v1	282	28	(	(	-LRB-
cord-278081-tk7vn1v1	282	29	RNPs	RNPs	NNP
cord-278081-tk7vn1v1	282	30	)	)	-RRB-
cord-278081-tk7vn1v1	282	31	.	.	.
cord-278081-tk7vn1v1	283	1	For	for	IN
cord-278081-tk7vn1v1	283	2	example	example	NN
cord-278081-tk7vn1v1	283	3	,	,	,
cord-278081-tk7vn1v1	283	4	in	in	IN
cord-278081-tk7vn1v1	283	5	some	some	DT
cord-278081-tk7vn1v1	283	6	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	283	7	fragments	fragment	NNS
cord-278081-tk7vn1v1	283	8	there	there	EX
cord-278081-tk7vn1v1	283	9	may	may	MD
cord-278081-tk7vn1v1	283	10	be	be	VB
cord-278081-tk7vn1v1	283	11	insufficient	insufficient	JJ
cord-278081-tk7vn1v1	283	12	quantities	quantity	NNS
cord-278081-tk7vn1v1	283	13	of	of	IN
cord-278081-tk7vn1v1	283	14	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	283	15	components	component	NNS
cord-278081-tk7vn1v1	283	16	(	(	-LRB-
cord-278081-tk7vn1v1	283	17	either	either	CC
cord-278081-tk7vn1v1	283	18	RNAs	rna	NNS
cord-278081-tk7vn1v1	283	19	or	or	CC
cord-278081-tk7vn1v1	283	20	proteins	protein	NNS
cord-278081-tk7vn1v1	283	21	)	)	-RRB-
cord-278081-tk7vn1v1	283	22	and	and	CC
cord-278081-tk7vn1v1	283	23	,	,	,
cord-278081-tk7vn1v1	283	24	therefore	therefore	RB
cord-278081-tk7vn1v1	283	25	,	,	,
cord-278081-tk7vn1v1	283	26	complete	complete	JJ
cord-278081-tk7vn1v1	283	27	functional	functional	JJ
cord-278081-tk7vn1v1	283	28	ribosomes	ribosome	NNS
cord-278081-tk7vn1v1	283	29	can	can	MD
cord-278081-tk7vn1v1	283	30	not	not	RB
cord-278081-tk7vn1v1	283	31	be	be	VB
cord-278081-tk7vn1v1	283	32	formed	form	VBN
cord-278081-tk7vn1v1	283	33	.	.	.
cord-278081-tk7vn1v1	284	1	There	there	EX
cord-278081-tk7vn1v1	284	2	may	may	MD
cord-278081-tk7vn1v1	284	3	also	also	RB
cord-278081-tk7vn1v1	284	4	be	be	VB
cord-278081-tk7vn1v1	284	5	incorporation	incorporation	NN
cord-278081-tk7vn1v1	284	6	of	of	IN
cord-278081-tk7vn1v1	284	7	viral	viral	JJ
cord-278081-tk7vn1v1	284	8	RNA	RNA	NNP
cord-278081-tk7vn1v1	284	9	and/or	and/or	CC
cord-278081-tk7vn1v1	284	10	viral	viral	JJ
cord-278081-tk7vn1v1	284	11	proteins	protein	NNS
cord-278081-tk7vn1v1	284	12	into	into	IN
cord-278081-tk7vn1v1	284	13	the	the	DT
cord-278081-tk7vn1v1	284	14	RNPs	rnp	NNS
cord-278081-tk7vn1v1	284	15	.	.	.
cord-278081-tk7vn1v1	285	1	Also	also	RB
cord-278081-tk7vn1v1	285	2	,	,	,
cord-278081-tk7vn1v1	285	3	overexpression	overexpression	NN
cord-278081-tk7vn1v1	285	4	of	of	IN
cord-278081-tk7vn1v1	285	5	X	x	NN
cord-278081-tk7vn1v1	285	6	-	-	HYPH
cord-278081-tk7vn1v1	285	7	linked	link	VBN
cord-278081-tk7vn1v1	285	8	spermine	spermine	NN
cord-278081-tk7vn1v1	285	9	synthase	synthase	NN
cord-278081-tk7vn1v1	285	10	and/or	and/or	CC
cord-278081-tk7vn1v1	285	11	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	285	12	/	/	SYM
cord-278081-tk7vn1v1	285	13	spermine	spermine	JJ
cord-278081-tk7vn1v1	285	14	N1	N1	NNP
cord-278081-tk7vn1v1	285	15	acetyltransferase	acetyltransferase	NN
cord-278081-tk7vn1v1	285	16	could	could	MD
cord-278081-tk7vn1v1	285	17	result	result	VB
cord-278081-tk7vn1v1	285	18	in	in	IN
cord-278081-tk7vn1v1	285	19	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	285	20	types	type	NNS
cord-278081-tk7vn1v1	285	21	and	and	CC
cord-278081-tk7vn1v1	285	22	levels	level	NNS
cord-278081-tk7vn1v1	285	23	of	of	IN
cord-278081-tk7vn1v1	285	24	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	285	25	in	in	IN
cord-278081-tk7vn1v1	285	26	the	the	DT
cord-278081-tk7vn1v1	285	27	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	285	28	and	and	CC
cord-278081-tk7vn1v1	285	29	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	285	30	fragments	fragment	NNS
cord-278081-tk7vn1v1	285	31	.	.	.
cord-278081-tk7vn1v1	286	1	For	for	IN
cord-278081-tk7vn1v1	286	2	example	example	NN
cord-278081-tk7vn1v1	286	3	,	,	,
cord-278081-tk7vn1v1	286	4	there	there	EX
cord-278081-tk7vn1v1	286	5	may	may	MD
cord-278081-tk7vn1v1	286	6	be	be	VB
cord-278081-tk7vn1v1	286	7	putrescine	putrescine	NN
cord-278081-tk7vn1v1	286	8	,	,	,
cord-278081-tk7vn1v1	286	9	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	286	10	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	286	11	,	,	,
cord-278081-tk7vn1v1	286	12	and/or	and/or	CC
cord-278081-tk7vn1v1	286	13	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	286	14	aggregates	aggregate	NNS
cord-278081-tk7vn1v1	286	15	of	of	IN
cord-278081-tk7vn1v1	286	16	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	286	17	in	in	IN
cord-278081-tk7vn1v1	286	18	the	the	DT
cord-278081-tk7vn1v1	286	19	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	286	20	that	that	WDT
cord-278081-tk7vn1v1	286	21	interfere	interfere	VBP
cord-278081-tk7vn1v1	286	22	with	with	IN
cord-278081-tk7vn1v1	286	23	RNA	RNA	NNP
cord-278081-tk7vn1v1	286	24	folding	folding	NN
cord-278081-tk7vn1v1	286	25	.	.	.
cord-278081-tk7vn1v1	287	1	Normally	normally	RB
cord-278081-tk7vn1v1	287	2	one	one	PRP
cord-278081-tk7vn1v1	287	3	would	would	MD
cord-278081-tk7vn1v1	287	4	expect	expect	VB
cord-278081-tk7vn1v1	287	5	only	only	RB
cord-278081-tk7vn1v1	287	6	spermine	spermine	JJ
cord-278081-tk7vn1v1	287	7	and	and	CC
cord-278081-tk7vn1v1	287	8	spermidine	spermidine	NN
cord-278081-tk7vn1v1	287	9	to	to	TO
cord-278081-tk7vn1v1	287	10	be	be	VB
cord-278081-tk7vn1v1	287	11	present	present	JJ
cord-278081-tk7vn1v1	287	12	in	in	IN
cord-278081-tk7vn1v1	287	13	large	large	JJ
cord-278081-tk7vn1v1	287	14	quantities	quantity	NNS
cord-278081-tk7vn1v1	287	15	.	.	.
cord-278081-tk7vn1v1	288	1	Extracellular	Extracellular	NNP
cord-278081-tk7vn1v1	288	2	release	release	NN
cord-278081-tk7vn1v1	288	3	(	(	-LRB-
cord-278081-tk7vn1v1	288	4	by	by	IN
cord-278081-tk7vn1v1	288	5	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	288	6	,	,	,
cord-278081-tk7vn1v1	288	7	necrosis	necrosis	NN
cord-278081-tk7vn1v1	288	8	,	,	,
cord-278081-tk7vn1v1	288	9	NETosis	NETosis	NNP
cord-278081-tk7vn1v1	288	10	)	)	-RRB-
cord-278081-tk7vn1v1	288	11	of	of	IN
cord-278081-tk7vn1v1	288	12	these	these	DT
cord-278081-tk7vn1v1	288	13	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	288	14	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	288	15	products	product	NNS
cord-278081-tk7vn1v1	288	16	could	could	MD
cord-278081-tk7vn1v1	288	17	provoke	provoke	VB
cord-278081-tk7vn1v1	288	18	an	an	DT
cord-278081-tk7vn1v1	288	19	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	288	20	reaction	reaction	NN
cord-278081-tk7vn1v1	288	21	that	that	IN
cord-278081-tk7vn1v1	288	22	later	later	RB
cord-278081-tk7vn1v1	288	23	targets	target	VBZ
cord-278081-tk7vn1v1	288	24	the	the	DT
cord-278081-tk7vn1v1	288	25	more	more	RBR
cord-278081-tk7vn1v1	288	26	abundant	abundant	JJ
cord-278081-tk7vn1v1	288	27	normal	normal	JJ
cord-278081-tk7vn1v1	288	28	products	product	NNS
cord-278081-tk7vn1v1	288	29	due	due	JJ
cord-278081-tk7vn1v1	288	30	to	to	IN
cord-278081-tk7vn1v1	288	31	epitope	epitope	NN
cord-278081-tk7vn1v1	288	32	spreading	spread	VBG
cord-278081-tk7vn1v1	288	33	.	.	.
cord-278081-tk7vn1v1	289	1	such	such	JJ
cord-278081-tk7vn1v1	289	2	as	as	IN
cord-278081-tk7vn1v1	289	3	Z	z	NN
cord-278081-tk7vn1v1	289	4	-	-	HYPH
cord-278081-tk7vn1v1	289	5	DNA	dna	NN
cord-278081-tk7vn1v1	289	6	,	,	,
cord-278081-tk7vn1v1	290	1	but	but	CC
cord-278081-tk7vn1v1	290	2	RA	RA	NNP
cord-278081-tk7vn1v1	290	3	is	be	VBZ
cord-278081-tk7vn1v1	290	4	primarily	primarily	RB
cord-278081-tk7vn1v1	290	5	behind	behind	IN
cord-278081-tk7vn1v1	290	6	the	the	DT
cord-278081-tk7vn1v1	290	7	synovial	synovial	JJ
cord-278081-tk7vn1v1	290	8	membrane	membrane	NN
cord-278081-tk7vn1v1	290	9	reducing	reduce	VBG
cord-278081-tk7vn1v1	290	10	full	full	JJ
cord-278081-tk7vn1v1	290	11	exposure	exposure	NN
cord-278081-tk7vn1v1	290	12	of	of	IN
cord-278081-tk7vn1v1	290	13	antigenic	antigenic	JJ
cord-278081-tk7vn1v1	290	14	and	and	CC
cord-278081-tk7vn1v1	290	15	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	290	16	material	material	NN
cord-278081-tk7vn1v1	290	17	to	to	IN
cord-278081-tk7vn1v1	290	18	the	the	DT
cord-278081-tk7vn1v1	290	19	immune	immune	JJ
cord-278081-tk7vn1v1	290	20	system	system	NN
cord-278081-tk7vn1v1	290	21	.	.	.
cord-278081-tk7vn1v1	291	1	However	however	RB
cord-278081-tk7vn1v1	291	2	,	,	,
cord-278081-tk7vn1v1	291	3	continual	continual	JJ
cord-278081-tk7vn1v1	291	4	attraction	attraction	NN
cord-278081-tk7vn1v1	291	5	of	of	IN
cord-278081-tk7vn1v1	291	6	neutrophils	neutrophil	NNS
cord-278081-tk7vn1v1	291	7	to	to	IN
cord-278081-tk7vn1v1	291	8	the	the	DT
cord-278081-tk7vn1v1	291	9	same	same	JJ
cord-278081-tk7vn1v1	291	10	confined	confine	VBN
cord-278081-tk7vn1v1	291	11	inflammation	inflammation	NN
cord-278081-tk7vn1v1	291	12	site	site	NN
cord-278081-tk7vn1v1	291	13	in	in	IN
cord-278081-tk7vn1v1	291	14	RA	RA	NNP
cord-278081-tk7vn1v1	291	15	where	where	WRB
cord-278081-tk7vn1v1	291	16	the	the	DT
cord-278081-tk7vn1v1	291	17	neutrophils	neutrophil	NNS
cord-278081-tk7vn1v1	291	18	undergo	undergo	VBP
cord-278081-tk7vn1v1	291	19	NETosis	netosis	NN
cord-278081-tk7vn1v1	291	20	in	in	IN
cord-278081-tk7vn1v1	291	21	an	an	DT
cord-278081-tk7vn1v1	291	22	ineffective	ineffective	JJ
cord-278081-tk7vn1v1	291	23	attempt	attempt	NN
cord-278081-tk7vn1v1	291	24	at	at	IN
cord-278081-tk7vn1v1	291	25	clearing	clear	VBG
cord-278081-tk7vn1v1	291	26	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	291	27	material	material	NN
cord-278081-tk7vn1v1	291	28	would	would	MD
cord-278081-tk7vn1v1	291	29	produce	produce	VB
cord-278081-tk7vn1v1	291	30	chronic	chronic	JJ
cord-278081-tk7vn1v1	291	31	local	local	JJ
cord-278081-tk7vn1v1	291	32	exposure	exposure	NN
cord-278081-tk7vn1v1	291	33	of	of	IN
cord-278081-tk7vn1v1	291	34	cells	cell	NNS
cord-278081-tk7vn1v1	291	35	and	and	CC
cord-278081-tk7vn1v1	291	36	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	291	37	material	material	NN
cord-278081-tk7vn1v1	291	38	to	to	IN
cord-278081-tk7vn1v1	291	39	the	the	DT
cord-278081-tk7vn1v1	291	40	neutrophil	neutrophil	NN
cord-278081-tk7vn1v1	291	41	's	's	POS
cord-278081-tk7vn1v1	291	42	active	active	JJ
cord-278081-tk7vn1v1	291	43	peptidyl	peptidyl	JJ
cord-278081-tk7vn1v1	291	44	arginine	arginine	NN
cord-278081-tk7vn1v1	291	45	deiminases	deiminase	NNS
cord-278081-tk7vn1v1	291	46	(	(	-LRB-
cord-278081-tk7vn1v1	291	47	PADs	pad	NNS
cord-278081-tk7vn1v1	291	48	)	)	-RRB-
cord-278081-tk7vn1v1	291	49	producing	produce	VBG
cord-278081-tk7vn1v1	291	50	high	high	JJ
cord-278081-tk7vn1v1	291	51	levels	level	NNS
cord-278081-tk7vn1v1	291	52	of	of	IN
cord-278081-tk7vn1v1	291	53	citrullinated	citrullinate	VBN
cord-278081-tk7vn1v1	291	54	proteins	protein	NNS
cord-278081-tk7vn1v1	291	55	(	(	-LRB-
cord-278081-tk7vn1v1	291	56	e.g.	e.g.	RB
cord-278081-tk7vn1v1	291	57	,	,	,
cord-278081-tk7vn1v1	291	58	collagen	collagen	NN
cord-278081-tk7vn1v1	291	59	)	)	-RRB-
cord-278081-tk7vn1v1	291	60	that	that	WDT
cord-278081-tk7vn1v1	291	61	eventually	eventually	RB
cord-278081-tk7vn1v1	291	62	provokes	provoke	VBZ
cord-278081-tk7vn1v1	291	63	the	the	DT
cord-278081-tk7vn1v1	291	64	adaptive	adaptive	JJ
cord-278081-tk7vn1v1	291	65	immune	immune	JJ
cord-278081-tk7vn1v1	291	66	system	system	NN
cord-278081-tk7vn1v1	291	67	into	into	IN
cord-278081-tk7vn1v1	291	68	producing	produce	VBG
cord-278081-tk7vn1v1	291	69	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	291	70	targeting	target	VBG
cord-278081-tk7vn1v1	291	71	the	the	DT
cord-278081-tk7vn1v1	291	72	modified	modify	VBN
cord-278081-tk7vn1v1	291	73	collagen	collagen	NN
cord-278081-tk7vn1v1	291	74	as	as	IN
cord-278081-tk7vn1v1	291	75	a	a	DT
cord-278081-tk7vn1v1	291	76	major	major	JJ
cord-278081-tk7vn1v1	291	77	autoantigen	autoantigen	NN
cord-278081-tk7vn1v1	291	78	in	in	IN
cord-278081-tk7vn1v1	291	79	RA	RA	NNP
cord-278081-tk7vn1v1	291	80	(	(	-LRB-
cord-278081-tk7vn1v1	291	81	85	85	CD
cord-278081-tk7vn1v1	291	82	)	)	-RRB-
cord-278081-tk7vn1v1	291	83	.	.	.
cord-278081-tk7vn1v1	292	1	In	in	IN
cord-278081-tk7vn1v1	292	2	a	a	DT
cord-278081-tk7vn1v1	292	3	similar	similar	JJ
cord-278081-tk7vn1v1	292	4	manner	manner	NN
cord-278081-tk7vn1v1	292	5	,	,	,
cord-278081-tk7vn1v1	292	6	MS	MS	NNP
cord-278081-tk7vn1v1	292	7	is	be	VBZ
cord-278081-tk7vn1v1	292	8	confined	confine	VBN
cord-278081-tk7vn1v1	292	9	behind	behind	IN
cord-278081-tk7vn1v1	292	10	the	the	DT
cord-278081-tk7vn1v1	292	11	bloodbrain	bloodbrain	NN
cord-278081-tk7vn1v1	292	12	barrier	barrier	NN
cord-278081-tk7vn1v1	292	13	reducing	reduce	VBG
cord-278081-tk7vn1v1	292	14	access	access	NN
cord-278081-tk7vn1v1	292	15	of	of	IN
cord-278081-tk7vn1v1	292	16	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	292	17	material	material	NN
cord-278081-tk7vn1v1	292	18	to	to	IN
cord-278081-tk7vn1v1	292	19	the	the	DT
cord-278081-tk7vn1v1	292	20	immune	immune	JJ
cord-278081-tk7vn1v1	292	21	system	system	NN
cord-278081-tk7vn1v1	292	22	but	but	CC
cord-278081-tk7vn1v1	292	23	,	,	,
cord-278081-tk7vn1v1	292	24	again	again	RB
cord-278081-tk7vn1v1	292	25	,	,	,
cord-278081-tk7vn1v1	292	26	neutrophils	neutrophil	NNS
cord-278081-tk7vn1v1	292	27	continually	continually	RB
cord-278081-tk7vn1v1	292	28	attracted	attract	VBD
cord-278081-tk7vn1v1	292	29	to	to	IN
cord-278081-tk7vn1v1	292	30	an	an	DT
cord-278081-tk7vn1v1	292	31	MS	MS	NNP
cord-278081-tk7vn1v1	292	32	lesion	lesion	NN
cord-278081-tk7vn1v1	292	33	could	could	MD
cord-278081-tk7vn1v1	292	34	be	be	VB
cord-278081-tk7vn1v1	292	35	releasing	release	VBG
cord-278081-tk7vn1v1	292	36	PADs	pad	NNS
cord-278081-tk7vn1v1	292	37	that	that	IN
cord-278081-tk7vn1v1	292	38	citrullinate	citrullinate	NN
cord-278081-tk7vn1v1	292	39	myelin	myelin	NN
cord-278081-tk7vn1v1	292	40	,	,	,
cord-278081-tk7vn1v1	292	41	eventually	eventually	RB
cord-278081-tk7vn1v1	292	42	triggering	trigger	VBG
cord-278081-tk7vn1v1	292	43	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	292	44	to	to	IN
cord-278081-tk7vn1v1	292	45	citrullinated	citrullinate	VBN
cord-278081-tk7vn1v1	292	46	myelin	myelin	JJ
cord-278081-tk7vn1v1	292	47	basic	basic	JJ
cord-278081-tk7vn1v1	292	48	protein	protein	NN
cord-278081-tk7vn1v1	292	49	which	which	WDT
cord-278081-tk7vn1v1	292	50	is	be	VBZ
cord-278081-tk7vn1v1	292	51	a	a	DT
cord-278081-tk7vn1v1	292	52	major	major	JJ
cord-278081-tk7vn1v1	292	53	autoantigen	autoantigen	NN
cord-278081-tk7vn1v1	292	54	in	in	IN
cord-278081-tk7vn1v1	292	55	MS	MS	NNP
cord-278081-tk7vn1v1	292	56	.	.	.
cord-278081-tk7vn1v1	293	1	SLE	SLE	NNP
cord-278081-tk7vn1v1	293	2	is	be	VBZ
cord-278081-tk7vn1v1	293	3	a	a	DT
cord-278081-tk7vn1v1	293	4	systemic	systemic	JJ
cord-278081-tk7vn1v1	293	5	disease	disease	NN
cord-278081-tk7vn1v1	293	6	suggesting	suggest	VBG
cord-278081-tk7vn1v1	293	7	that	that	IN
cord-278081-tk7vn1v1	293	8	the	the	DT
cord-278081-tk7vn1v1	293	9	immune	immune	JJ
cord-278081-tk7vn1v1	293	10	system	system	NN
cord-278081-tk7vn1v1	293	11	can	can	MD
cord-278081-tk7vn1v1	293	12	more	more	RBR
cord-278081-tk7vn1v1	293	13	readily	readily	RB
cord-278081-tk7vn1v1	293	14	react	react	VB
cord-278081-tk7vn1v1	293	15	to	to	IN
cord-278081-tk7vn1v1	293	16	the	the	DT
cord-278081-tk7vn1v1	293	17	broad	broad	JJ
cord-278081-tk7vn1v1	293	18	array	array	NN
cord-278081-tk7vn1v1	293	19	of	of	IN
cord-278081-tk7vn1v1	293	20	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	293	21	material	material	NN
cord-278081-tk7vn1v1	293	22	seen	see	VBN
cord-278081-tk7vn1v1	293	23	in	in	IN
cord-278081-tk7vn1v1	293	24	SLE	SLE	NNP
cord-278081-tk7vn1v1	293	25	and	and	CC
cord-278081-tk7vn1v1	293	26	generate	generate	VB
cord-278081-tk7vn1v1	293	27	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	293	28	.	.	.
cord-278081-tk7vn1v1	294	1	Compared	compare	VBN
cord-278081-tk7vn1v1	294	2	to	to	IN
cord-278081-tk7vn1v1	294	3	RA	RA	NNP
cord-278081-tk7vn1v1	294	4	or	or	CC
cord-278081-tk7vn1v1	294	5	MS	MS	NNP
cord-278081-tk7vn1v1	294	6	,	,	,
cord-278081-tk7vn1v1	294	7	the	the	DT
cord-278081-tk7vn1v1	294	8	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	294	9	,	,	,
cord-278081-tk7vn1v1	294	10	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	294	11	and	and	CC
cord-278081-tk7vn1v1	294	12	complexes	complex	NNS
cord-278081-tk7vn1v1	294	13	of	of	IN
cord-278081-tk7vn1v1	294	14	the	the	DT
cord-278081-tk7vn1v1	294	15	two	two	CD
cord-278081-tk7vn1v1	294	16	in	in	IN
cord-278081-tk7vn1v1	294	17	SLE	SLE	NNP
cord-278081-tk7vn1v1	294	18	have	have	VBP
cord-278081-tk7vn1v1	294	19	easier	easy	JJR
cord-278081-tk7vn1v1	294	20	access	access	NN
cord-278081-tk7vn1v1	294	21	to	to	IN
cord-278081-tk7vn1v1	294	22	the	the	DT
cord-278081-tk7vn1v1	294	23	circulatory	circulatory	JJ
cord-278081-tk7vn1v1	294	24	system	system	NN
cord-278081-tk7vn1v1	294	25	allowing	allow	VBG
cord-278081-tk7vn1v1	294	26	the	the	DT
cord-278081-tk7vn1v1	294	27	reaction	reaction	NN
cord-278081-tk7vn1v1	294	28	to	to	TO
cord-278081-tk7vn1v1	294	29	spread	spread	VB
cord-278081-tk7vn1v1	294	30	to	to	IN
cord-278081-tk7vn1v1	294	31	and	and	CC
cord-278081-tk7vn1v1	294	32	deposit	deposit	VB
cord-278081-tk7vn1v1	294	33	in	in	IN
cord-278081-tk7vn1v1	294	34	different	different	JJ
cord-278081-tk7vn1v1	294	35	organs	organ	NNS
cord-278081-tk7vn1v1	294	36	rather	rather	RB
cord-278081-tk7vn1v1	294	37	than	than	IN
cord-278081-tk7vn1v1	294	38	being	be	VBG
cord-278081-tk7vn1v1	294	39	confined	confine	VBN
cord-278081-tk7vn1v1	294	40	behind	behind	IN
cord-278081-tk7vn1v1	294	41	a	a	DT
cord-278081-tk7vn1v1	294	42	membrane	membrane	NN
cord-278081-tk7vn1v1	294	43	barrier	barrier	NN
cord-278081-tk7vn1v1	294	44	.	.	.
cord-278081-tk7vn1v1	295	1	SjS	SjS	NNP
cord-278081-tk7vn1v1	295	2	can	can	MD
cord-278081-tk7vn1v1	295	3	be	be	VB
cord-278081-tk7vn1v1	295	4	a	a	DT
cord-278081-tk7vn1v1	295	5	primary	primary	JJ
cord-278081-tk7vn1v1	295	6	disease	disease	NN
cord-278081-tk7vn1v1	295	7	or	or	CC
cord-278081-tk7vn1v1	295	8	it	-PRON-	PRP
cord-278081-tk7vn1v1	295	9	can	can	MD
cord-278081-tk7vn1v1	295	10	be	be	VB
cord-278081-tk7vn1v1	295	11	secondary	secondary	JJ
cord-278081-tk7vn1v1	295	12	to	to	IN
cord-278081-tk7vn1v1	295	13	SLE	SLE	NNP
cord-278081-tk7vn1v1	295	14	,	,	,
cord-278081-tk7vn1v1	295	15	RA	RA	NNP
cord-278081-tk7vn1v1	295	16	or	or	CC
cord-278081-tk7vn1v1	295	17	MS	MS	NNP
cord-278081-tk7vn1v1	295	18	.	.	.
cord-278081-tk7vn1v1	296	1	This	this	DT
cord-278081-tk7vn1v1	296	2	suggests	suggest	VBZ
cord-278081-tk7vn1v1	296	3	that	that	IN
cord-278081-tk7vn1v1	296	4	there	there	EX
cord-278081-tk7vn1v1	296	5	could	could	MD
cord-278081-tk7vn1v1	296	6	be	be	VB
cord-278081-tk7vn1v1	296	7	similar	similar	JJ
cord-278081-tk7vn1v1	296	8	mechanisms	mechanism	NNS
cord-278081-tk7vn1v1	296	9	occurring	occur	VBG
cord-278081-tk7vn1v1	296	10	in	in	IN
cord-278081-tk7vn1v1	296	11	all	all	DT
cord-278081-tk7vn1v1	296	12	four	four	CD
cord-278081-tk7vn1v1	296	13	of	of	IN
cord-278081-tk7vn1v1	296	14	these	these	DT
cord-278081-tk7vn1v1	296	15	disorders	disorder	NNS
cord-278081-tk7vn1v1	296	16	.	.	.
cord-278081-tk7vn1v1	297	1	Involvement	involvement	NN
cord-278081-tk7vn1v1	297	2	of	of	IN
cord-278081-tk7vn1v1	297	3	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	297	4	,	,	,
cord-278081-tk7vn1v1	297	5	possibly	possibly	RB
cord-278081-tk7vn1v1	297	6	due	due	JJ
cord-278081-tk7vn1v1	297	7	to	to	IN
cord-278081-tk7vn1v1	297	8	loss	loss	NN
cord-278081-tk7vn1v1	297	9	of	of	IN
cord-278081-tk7vn1v1	297	10	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	297	11	control	control	NN
cord-278081-tk7vn1v1	297	12	of	of	IN
cord-278081-tk7vn1v1	297	13	X	x	NN
cord-278081-tk7vn1v1	297	14	-	-	HYPH
cord-278081-tk7vn1v1	297	15	linked	link	VBN
cord-278081-tk7vn1v1	297	16	polyamine	polyamine	NN
cord-278081-tk7vn1v1	297	17	genes	gene	NNS
cord-278081-tk7vn1v1	297	18	,	,	,
cord-278081-tk7vn1v1	297	19	is	be	VBZ
cord-278081-tk7vn1v1	297	20	suspected	suspect	VBN
cord-278081-tk7vn1v1	297	21	in	in	IN
cord-278081-tk7vn1v1	297	22	SjS	sjs	NN
cord-278081-tk7vn1v1	297	23	since	since	IN
cord-278081-tk7vn1v1	297	24	the	the	DT
cord-278081-tk7vn1v1	297	25	appearance	appearance	NN
cord-278081-tk7vn1v1	297	26	of	of	IN
cord-278081-tk7vn1v1	297	27	acrolein	acrolein	NN
cord-278081-tk7vn1v1	297	28	conjugated	conjugate	VBN
cord-278081-tk7vn1v1	297	29	proteins	protein	NNS
cord-278081-tk7vn1v1	297	30	is	be	VBZ
cord-278081-tk7vn1v1	297	31	related	relate	VBN
cord-278081-tk7vn1v1	297	32	to	to	IN
cord-278081-tk7vn1v1	297	33	the	the	DT
cord-278081-tk7vn1v1	297	34	intensity	intensity	NN
cord-278081-tk7vn1v1	297	35	of	of	IN
cord-278081-tk7vn1v1	297	36	SjS	sjs	NN
cord-278081-tk7vn1v1	297	37	and	and	CC
cord-278081-tk7vn1v1	297	38	acrolein	acrolein	NN
cord-278081-tk7vn1v1	297	39	is	be	VBZ
cord-278081-tk7vn1v1	297	40	an	an	DT
cord-278081-tk7vn1v1	297	41	oxidation	oxidation	NN
cord-278081-tk7vn1v1	297	42	product	product	NN
cord-278081-tk7vn1v1	297	43	of	of	IN
cord-278081-tk7vn1v1	297	44	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	297	45	(	(	-LRB-
cord-278081-tk7vn1v1	297	46	88	88	CD
cord-278081-tk7vn1v1	297	47	)	)	-RRB-
cord-278081-tk7vn1v1	297	48	.	.	.
cord-278081-tk7vn1v1	298	1	The	the	DT
cord-278081-tk7vn1v1	298	2	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	298	3	may	may	MD
cord-278081-tk7vn1v1	298	4	even	even	RB
cord-278081-tk7vn1v1	298	5	play	play	VB
cord-278081-tk7vn1v1	298	6	a	a	DT
cord-278081-tk7vn1v1	298	7	role	role	NN
cord-278081-tk7vn1v1	298	8	in	in	IN
cord-278081-tk7vn1v1	298	9	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	298	10	's	's	POS
cord-278081-tk7vn1v1	298	11	disease	disease	NN
cord-278081-tk7vn1v1	298	12	(	(	-LRB-
cord-278081-tk7vn1v1	298	13	ALZ	ALZ	NNP
cord-278081-tk7vn1v1	298	14	)	)	-RRB-
cord-278081-tk7vn1v1	298	15	since	since	IN
cord-278081-tk7vn1v1	298	16	there	there	EX
cord-278081-tk7vn1v1	298	17	is	be	VBZ
cord-278081-tk7vn1v1	298	18	a	a	DT
cord-278081-tk7vn1v1	298	19	female	female	JJ
cord-278081-tk7vn1v1	298	20	bias	bias	NN
cord-278081-tk7vn1v1	298	21	in	in	IN
cord-278081-tk7vn1v1	298	22	the	the	DT
cord-278081-tk7vn1v1	298	23	disease	disease	NN
cord-278081-tk7vn1v1	298	24	and	and	CC
cord-278081-tk7vn1v1	298	25	there	there	EX
cord-278081-tk7vn1v1	298	26	are	be	VBP
cord-278081-tk7vn1v1	298	27	autoantibodies	autoantibody	NNS
cord-278081-tk7vn1v1	298	28	involved	involve	VBN
cord-278081-tk7vn1v1	298	29	in	in	IN
cord-278081-tk7vn1v1	298	30	ALZ	ALZ	NNP
cord-278081-tk7vn1v1	298	31	(	(	-LRB-
cord-278081-tk7vn1v1	298	32	95	95	CD
cord-278081-tk7vn1v1	298	33	)	)	-RRB-
cord-278081-tk7vn1v1	298	34	.	.	.
cord-278081-tk7vn1v1	299	1	In	in	IN
cord-278081-tk7vn1v1	299	2	addition	addition	NN
cord-278081-tk7vn1v1	299	3	,	,	,
cord-278081-tk7vn1v1	299	4	polyamine	polyamine	NN
cord-278081-tk7vn1v1	299	5	levels	level	NNS
cord-278081-tk7vn1v1	299	6	are	be	VBP
cord-278081-tk7vn1v1	299	7	altered	alter	VBN
cord-278081-tk7vn1v1	299	8	in	in	IN
cord-278081-tk7vn1v1	299	9	ALZ	ALZ	NNP
cord-278081-tk7vn1v1	299	10	(	(	-LRB-
cord-278081-tk7vn1v1	299	11	96	96	CD
cord-278081-tk7vn1v1	299	12	,	,	,
cord-278081-tk7vn1v1	299	13	97	97	CD
cord-278081-tk7vn1v1	299	14	)	)	-RRB-
cord-278081-tk7vn1v1	299	15	along	along	IN
cord-278081-tk7vn1v1	299	16	with	with	IN
cord-278081-tk7vn1v1	299	17	increased	increase	VBN
cord-278081-tk7vn1v1	299	18	acrolein	acrolein	NN
cord-278081-tk7vn1v1	299	19	(	(	-LRB-
cord-278081-tk7vn1v1	299	20	98	98	CD
cord-278081-tk7vn1v1	299	21	)	)	-RRB-
cord-278081-tk7vn1v1	299	22	;	;	:
cord-278081-tk7vn1v1	299	23	SAM	SAM	NNP
cord-278081-tk7vn1v1	299	24	levels	level	NNS
cord-278081-tk7vn1v1	299	25	are	be	VBP
cord-278081-tk7vn1v1	299	26	greatly	greatly	RB
cord-278081-tk7vn1v1	299	27	decreased	decrease	VBN
cord-278081-tk7vn1v1	299	28	(	(	-LRB-
cord-278081-tk7vn1v1	299	29	99	99	CD
cord-278081-tk7vn1v1	299	30	)	)	-RRB-
cord-278081-tk7vn1v1	299	31	;	;	:
cord-278081-tk7vn1v1	299	32	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	299	33	are	be	VBP
cord-278081-tk7vn1v1	299	34	involved	involve	VBN
cord-278081-tk7vn1v1	299	35	in	in	IN
cord-278081-tk7vn1v1	299	36	plaque	plaque	NN
cord-278081-tk7vn1v1	299	37	formation	formation	NN
cord-278081-tk7vn1v1	299	38	(	(	-LRB-
cord-278081-tk7vn1v1	299	39	100	100	CD
cord-278081-tk7vn1v1	299	40	)	)	-RRB-
cord-278081-tk7vn1v1	299	41	and	and	CC
cord-278081-tk7vn1v1	299	42	nucleolar	nucleolar	NNP
cord-278081-tk7vn1v1	299	43	poly	poly	NNP
cord-278081-tk7vn1v1	299	44	(	(	-LRB-
cord-278081-tk7vn1v1	299	45	ADP	ADP	NNP
cord-278081-tk7vn1v1	299	46	-	-	HYPH
cord-278081-tk7vn1v1	299	47	ribose	ribose	NN
cord-278081-tk7vn1v1	299	48	)	)	-RRB-
cord-278081-tk7vn1v1	299	49	polymerase	polymerase	NN
cord-278081-tk7vn1v1	299	50	1	1	CD
cord-278081-tk7vn1v1	299	51	(	(	-LRB-
cord-278081-tk7vn1v1	299	52	PARP1	parp1	NN
cord-278081-tk7vn1v1	299	53	)	)	-RRB-
cord-278081-tk7vn1v1	299	54	is	be	VBZ
cord-278081-tk7vn1v1	299	55	decreased	decrease	VBN
cord-278081-tk7vn1v1	299	56	in	in	IN
cord-278081-tk7vn1v1	299	57	ALZ	ALZ	NNP
cord-278081-tk7vn1v1	299	58	(	(	-LRB-
cord-278081-tk7vn1v1	299	59	101	101	CD
cord-278081-tk7vn1v1	299	60	)	)	-RRB-
cord-278081-tk7vn1v1	299	61	.	.	.
cord-278081-tk7vn1v1	300	1	Cellular	cellular	JJ
cord-278081-tk7vn1v1	300	2	stress	stress	NN
cord-278081-tk7vn1v1	300	3	that	that	WDT
cord-278081-tk7vn1v1	300	4	leads	lead	VBZ
cord-278081-tk7vn1v1	300	5	to	to	IN
cord-278081-tk7vn1v1	300	6	disruption	disruption	NN
cord-278081-tk7vn1v1	300	7	of	of	IN
cord-278081-tk7vn1v1	300	8	the	the	DT
cord-278081-tk7vn1v1	300	9	inactive	inactive	JJ
cord-278081-tk7vn1v1	300	10	X	x	NN
cord-278081-tk7vn1v1	300	11	chromosome	chromosome	NN
cord-278081-tk7vn1v1	300	12	and/or	and/or	CC
cord-278081-tk7vn1v1	301	1	the	the	DT
cord-278081-tk7vn1v1	301	2	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	301	3	could	could	MD
cord-278081-tk7vn1v1	301	4	play	play	VB
cord-278081-tk7vn1v1	301	5	a	a	DT
cord-278081-tk7vn1v1	301	6	role	role	NN
cord-278081-tk7vn1v1	301	7	in	in	IN
cord-278081-tk7vn1v1	301	8	the	the	DT
cord-278081-tk7vn1v1	301	9	altered	altered	JJ
cord-278081-tk7vn1v1	301	10	polyamine	polyamine	NN
cord-278081-tk7vn1v1	301	11	activity	activity	NN
cord-278081-tk7vn1v1	301	12	,	,	,
cord-278081-tk7vn1v1	301	13	decreases	decrease	VBZ
cord-278081-tk7vn1v1	301	14	in	in	IN
cord-278081-tk7vn1v1	301	15	SAM	SAM	NNP
cord-278081-tk7vn1v1	301	16	,	,	,
cord-278081-tk7vn1v1	301	17	decreases	decrease	VBZ
cord-278081-tk7vn1v1	301	18	in	in	IN
cord-278081-tk7vn1v1	301	19	PARP1	parp1	NN
cord-278081-tk7vn1v1	301	20	,	,	,
cord-278081-tk7vn1v1	301	21	and	and	CC
cord-278081-tk7vn1v1	301	22	appearance	appearance	NN
cord-278081-tk7vn1v1	301	23	of	of	IN
cord-278081-tk7vn1v1	301	24	acrolein	acrolein	NN
cord-278081-tk7vn1v1	301	25	.	.	.
cord-278081-tk7vn1v1	302	1	The	the	DT
cord-278081-tk7vn1v1	302	2	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	302	3	as	as	IN
cord-278081-tk7vn1v1	302	4	a	a	DT
cord-278081-tk7vn1v1	302	5	whole	whole	NN
cord-278081-tk7vn1v1	302	6	or	or	CC
cord-278081-tk7vn1v1	302	7	in	in	IN
cord-278081-tk7vn1v1	302	8	parts	part	NNS
cord-278081-tk7vn1v1	302	9	(	(	-LRB-
cord-278081-tk7vn1v1	302	10	part	part	NN
cord-278081-tk7vn1v1	302	11	1	1	CD
cord-278081-tk7vn1v1	302	12	:	:	:
cord-278081-tk7vn1v1	302	13	inactive	inactive	JJ
cord-278081-tk7vn1v1	302	14	X	x	NN
cord-278081-tk7vn1v1	302	15	disruption	disruption	NN
cord-278081-tk7vn1v1	302	16	and/or	and/or	CC
cord-278081-tk7vn1v1	302	17	part	part	NN
cord-278081-tk7vn1v1	302	18	2	2	CD
cord-278081-tk7vn1v1	302	19	:	:	:
cord-278081-tk7vn1v1	302	20	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	302	21	disruption	disruption	NN
cord-278081-tk7vn1v1	302	22	)	)	-RRB-
cord-278081-tk7vn1v1	302	23	could	could	MD
cord-278081-tk7vn1v1	302	24	have	have	VB
cord-278081-tk7vn1v1	302	25	a	a	DT
cord-278081-tk7vn1v1	302	26	role	role	NN
cord-278081-tk7vn1v1	302	27	in	in	IN
cord-278081-tk7vn1v1	302	28	some	some	DT
cord-278081-tk7vn1v1	302	29	cancers	cancer	NNS
cord-278081-tk7vn1v1	302	30	.	.	.
cord-278081-tk7vn1v1	303	1	The	the	DT
cord-278081-tk7vn1v1	303	2	inactive	inactive	JJ
cord-278081-tk7vn1v1	303	3	X	x	NN
cord-278081-tk7vn1v1	303	4	chromosome	chromosome	NN
cord-278081-tk7vn1v1	303	5	is	be	VBZ
cord-278081-tk7vn1v1	303	6	often	often	RB
cord-278081-tk7vn1v1	303	7	missing	miss	VBG
cord-278081-tk7vn1v1	303	8	in	in	IN
cord-278081-tk7vn1v1	303	9	tumor	tumor	NN
cord-278081-tk7vn1v1	303	10	cells	cell	NNS
cord-278081-tk7vn1v1	303	11	from	from	IN
cord-278081-tk7vn1v1	303	12	breast	breast	NN
cord-278081-tk7vn1v1	303	13	and	and	CC
cord-278081-tk7vn1v1	303	14	ovarian	ovarian	JJ
cord-278081-tk7vn1v1	303	15	cancers	cancer	NNS
cord-278081-tk7vn1v1	303	16	(	(	-LRB-
cord-278081-tk7vn1v1	303	17	102	102	CD
cord-278081-tk7vn1v1	303	18	)	)	-RRB-
cord-278081-tk7vn1v1	303	19	.	.	.
cord-278081-tk7vn1v1	304	1	The	the	DT
cord-278081-tk7vn1v1	304	2	inactive	inactive	JJ
cord-278081-tk7vn1v1	304	3	X	x	NN
cord-278081-tk7vn1v1	304	4	may	may	MD
cord-278081-tk7vn1v1	304	5	have	have	VB
cord-278081-tk7vn1v1	304	6	reactivated	reactivate	VBN
cord-278081-tk7vn1v1	304	7	from	from	IN
cord-278081-tk7vn1v1	304	8	a	a	DT
cord-278081-tk7vn1v1	304	9	decrease	decrease	NN
cord-278081-tk7vn1v1	304	10	in	in	IN
cord-278081-tk7vn1v1	304	11	methylation	methylation	NN
cord-278081-tk7vn1v1	304	12	(	(	-LRB-
cord-278081-tk7vn1v1	304	13	possibly	possibly	RB
cord-278081-tk7vn1v1	304	14	due	due	JJ
cord-278081-tk7vn1v1	304	15	to	to	IN
cord-278081-tk7vn1v1	304	16	over	over	IN
cord-278081-tk7vn1v1	304	17	activity	activity	NN
cord-278081-tk7vn1v1	304	18	of	of	IN
cord-278081-tk7vn1v1	304	19	polyamine	polyamine	NN
cord-278081-tk7vn1v1	304	20	synthesis	synthesis	NN
cord-278081-tk7vn1v1	304	21	and	and	CC
cord-278081-tk7vn1v1	304	22	recycling	recycling	NN
cord-278081-tk7vn1v1	304	23	)	)	-RRB-
cord-278081-tk7vn1v1	304	24	or	or	CC
cord-278081-tk7vn1v1	304	25	the	the	DT
cord-278081-tk7vn1v1	304	26	inactive	inactive	JJ
cord-278081-tk7vn1v1	304	27	X	x	NN
cord-278081-tk7vn1v1	304	28	was	be	VBD
cord-278081-tk7vn1v1	304	29	lost	lose	VBN
cord-278081-tk7vn1v1	304	30	due	due	IN
cord-278081-tk7vn1v1	304	31	to	to	IN
cord-278081-tk7vn1v1	304	32	improper	improper	JJ
cord-278081-tk7vn1v1	304	33	segregation	segregation	NN
cord-278081-tk7vn1v1	304	34	of	of	IN
cord-278081-tk7vn1v1	304	35	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	304	36	to	to	IN
cord-278081-tk7vn1v1	304	37	daughter	daughter	NN
cord-278081-tk7vn1v1	304	38	cells	cell	NNS
cord-278081-tk7vn1v1	304	39	(	(	-LRB-
cord-278081-tk7vn1v1	304	40	possibly	possibly	RB
cord-278081-tk7vn1v1	304	41	due	due	JJ
cord-278081-tk7vn1v1	304	42	to	to	IN
cord-278081-tk7vn1v1	304	43	centromere	centromere	NNP
cord-278081-tk7vn1v1	304	44	assembly	assembly	NN
cord-278081-tk7vn1v1	304	45	in	in	IN
cord-278081-tk7vn1v1	304	46	the	the	DT
cord-278081-tk7vn1v1	304	47	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	304	48	)	)	-RRB-
cord-278081-tk7vn1v1	304	49	.	.	.
cord-278081-tk7vn1v1	305	1	Viruses	virus	NNS
cord-278081-tk7vn1v1	305	2	could	could	MD
cord-278081-tk7vn1v1	305	3	be	be	VB
cord-278081-tk7vn1v1	305	4	involved	involve	VBN
cord-278081-tk7vn1v1	305	5	in	in	IN
cord-278081-tk7vn1v1	305	6	the	the	DT
cord-278081-tk7vn1v1	305	7	loss	loss	NN
cord-278081-tk7vn1v1	305	8	of	of	IN
cord-278081-tk7vn1v1	305	9	X	x	NN
cord-278081-tk7vn1v1	305	10	inactivation	inactivation	NN
cord-278081-tk7vn1v1	305	11	since	since	IN
cord-278081-tk7vn1v1	305	12	viruses	virus	NNS
cord-278081-tk7vn1v1	305	13	increase	increase	VBP
cord-278081-tk7vn1v1	305	14	polyamine	polyamine	NN
cord-278081-tk7vn1v1	305	15	levels	level	NNS
cord-278081-tk7vn1v1	305	16	in	in	IN
cord-278081-tk7vn1v1	305	17	order	order	NN
cord-278081-tk7vn1v1	305	18	to	to	TO
cord-278081-tk7vn1v1	305	19	increase	increase	VB
cord-278081-tk7vn1v1	305	20	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	305	21	activity	activity	NN
cord-278081-tk7vn1v1	305	22	for	for	IN
cord-278081-tk7vn1v1	305	23	their	-PRON-	PRP$
cord-278081-tk7vn1v1	305	24	benefit	benefit	NN
cord-278081-tk7vn1v1	305	25	,	,	,
cord-278081-tk7vn1v1	305	26	as	as	IN
cord-278081-tk7vn1v1	305	27	exemplified	exemplify	VBN
cord-278081-tk7vn1v1	305	28	by	by	IN
cord-278081-tk7vn1v1	305	29	EBV	EBV	NNP
cord-278081-tk7vn1v1	305	30	induction	induction	NN
cord-278081-tk7vn1v1	305	31	of	of	IN
cord-278081-tk7vn1v1	305	32	ODC	ODC	NNP
cord-278081-tk7vn1v1	305	33	,	,	,
cord-278081-tk7vn1v1	305	34	SDS	SDS	NNP
cord-278081-tk7vn1v1	305	35	,	,	,
cord-278081-tk7vn1v1	305	36	and	and	CC
cord-278081-tk7vn1v1	305	37	SMS	SMS	NNP
cord-278081-tk7vn1v1	305	38	via	via	IN
cord-278081-tk7vn1v1	305	39	increased	increase	VBN
cord-278081-tk7vn1v1	305	40	MYC	MYC	NNP
cord-278081-tk7vn1v1	305	41	activity	activity	NN
cord-278081-tk7vn1v1	305	42	.	.	.
cord-278081-tk7vn1v1	306	1	The	the	DT
cord-278081-tk7vn1v1	306	2	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	306	3	reduction	reduction	NN
cord-278081-tk7vn1v1	306	4	in	in	IN
cord-278081-tk7vn1v1	306	5	SAM	SAM	NNP
cord-278081-tk7vn1v1	306	6	due	due	IN
cord-278081-tk7vn1v1	306	7	to	to	IN
cord-278081-tk7vn1v1	306	8	polyamine	polyamine	NN
cord-278081-tk7vn1v1	306	9	synthesis	synthesis	NN
cord-278081-tk7vn1v1	306	10	would	would	MD
cord-278081-tk7vn1v1	306	11	make	make	VB
cord-278081-tk7vn1v1	306	12	it	-PRON-	PRP
cord-278081-tk7vn1v1	306	13	difficult	difficult	JJ
cord-278081-tk7vn1v1	306	14	for	for	IN
cord-278081-tk7vn1v1	306	15	the	the	DT
cord-278081-tk7vn1v1	306	16	cell	cell	NN
cord-278081-tk7vn1v1	306	17	to	to	TO
cord-278081-tk7vn1v1	306	18	maintain	maintain	VB
cord-278081-tk7vn1v1	306	19	chromatin	chromatin	NN
cord-278081-tk7vn1v1	306	20	methylation	methylation	NN
cord-278081-tk7vn1v1	306	21	required	require	VBN
cord-278081-tk7vn1v1	306	22	for	for	IN
cord-278081-tk7vn1v1	306	23	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	306	24	silencing	silencing	NN
cord-278081-tk7vn1v1	306	25	in	in	IN
cord-278081-tk7vn1v1	306	26	the	the	DT
cord-278081-tk7vn1v1	306	27	X	x	NN
cord-278081-tk7vn1v1	306	28	chromosome	chromosome	NN
cord-278081-tk7vn1v1	306	29	and	and	CC
cord-278081-tk7vn1v1	306	30	other	other	JJ
cord-278081-tk7vn1v1	306	31	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	306	32	leading	lead	VBG
cord-278081-tk7vn1v1	306	33	to	to	IN
cord-278081-tk7vn1v1	306	34	disruption	disruption	NN
cord-278081-tk7vn1v1	306	35	of	of	IN
cord-278081-tk7vn1v1	306	36	control	control	NN
cord-278081-tk7vn1v1	306	37	of	of	IN
cord-278081-tk7vn1v1	306	38	oncogenes	oncogene	NNS
cord-278081-tk7vn1v1	306	39	and	and	CC
cord-278081-tk7vn1v1	306	40	tumor	tumor	NN
cord-278081-tk7vn1v1	306	41	suppressor	suppressor	NN
cord-278081-tk7vn1v1	306	42	genes	gene	NNS
cord-278081-tk7vn1v1	306	43	and	and	CC
cord-278081-tk7vn1v1	306	44	there	there	EX
cord-278081-tk7vn1v1	306	45	is	be	VBZ
cord-278081-tk7vn1v1	306	46	the	the	DT
cord-278081-tk7vn1v1	306	47	possibility	possibility	NN
cord-278081-tk7vn1v1	306	48	of	of	IN
cord-278081-tk7vn1v1	306	49	opening	open	VBG
cord-278081-tk7vn1v1	306	50	previously	previously	RB
cord-278081-tk7vn1v1	306	51	sequestered	sequester	VBN
cord-278081-tk7vn1v1	306	52	viruses	virus	NNS
cord-278081-tk7vn1v1	306	53	that	that	WDT
cord-278081-tk7vn1v1	306	54	then	then	RB
cord-278081-tk7vn1v1	306	55	try	try	VBP
cord-278081-tk7vn1v1	306	56	to	to	TO
cord-278081-tk7vn1v1	306	57	take	take	VB
cord-278081-tk7vn1v1	306	58	control	control	NN
cord-278081-tk7vn1v1	306	59	of	of	IN
cord-278081-tk7vn1v1	306	60	the	the	DT
cord-278081-tk7vn1v1	306	61	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	306	62	.	.	.
cord-278081-tk7vn1v1	307	1	The	the	DT
cord-278081-tk7vn1v1	307	2	inactive	inactive	JJ
cord-278081-tk7vn1v1	307	3	X	x	NN
cord-278081-tk7vn1v1	307	4	has	have	VBZ
cord-278081-tk7vn1v1	307	5	the	the	DT
cord-278081-tk7vn1v1	307	6	greatest	great	JJS
cord-278081-tk7vn1v1	307	7	demands	demand	NNS
cord-278081-tk7vn1v1	307	8	for	for	IN
cord-278081-tk7vn1v1	307	9	methylation	methylation	NN
cord-278081-tk7vn1v1	308	1	but	but	CC
cord-278081-tk7vn1v1	308	2	it	-PRON-	PRP
cord-278081-tk7vn1v1	308	3	is	be	VBZ
cord-278081-tk7vn1v1	308	4	the	the	DT
cord-278081-tk7vn1v1	308	5	last	last	JJ
cord-278081-tk7vn1v1	308	6	chromosome	chromosome	NN
cord-278081-tk7vn1v1	308	7	to	to	TO
cord-278081-tk7vn1v1	308	8	be	be	VB
cord-278081-tk7vn1v1	308	9	replicated	replicate	VBN
cord-278081-tk7vn1v1	308	10	and	and	CC
cord-278081-tk7vn1v1	308	11	repackaged	repackage	VBN
cord-278081-tk7vn1v1	308	12	in	in	IN
cord-278081-tk7vn1v1	308	13	late	late	JJ
cord-278081-tk7vn1v1	308	14	S	S	NNP
cord-278081-tk7vn1v1	308	15	phase	phase	NN
cord-278081-tk7vn1v1	308	16	or	or	CC
cord-278081-tk7vn1v1	308	17	even	even	RB
cord-278081-tk7vn1v1	308	18	early	early	JJ
cord-278081-tk7vn1v1	308	19	G2	G2	NNP
cord-278081-tk7vn1v1	308	20	when	when	WRB
cord-278081-tk7vn1v1	308	21	SAM	SAM	NNP
cord-278081-tk7vn1v1	308	22	levels	level	NNS
cord-278081-tk7vn1v1	308	23	would	would	MD
cord-278081-tk7vn1v1	308	24	have	have	VB
cord-278081-tk7vn1v1	308	25	already	already	RB
cord-278081-tk7vn1v1	308	26	been	be	VBN
cord-278081-tk7vn1v1	308	27	impacted	impact	VBN
cord-278081-tk7vn1v1	308	28	by	by	IN
cord-278081-tk7vn1v1	308	29	methylation	methylation	NN
cord-278081-tk7vn1v1	308	30	of	of	IN
cord-278081-tk7vn1v1	308	31	other	other	JJ
cord-278081-tk7vn1v1	308	32	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	308	33	.	.	.
cord-278081-tk7vn1v1	309	1	Reactivation	reactivation	NN
cord-278081-tk7vn1v1	309	2	or	or	CC
cord-278081-tk7vn1v1	309	3	loss	loss	NN
cord-278081-tk7vn1v1	309	4	of	of	IN
cord-278081-tk7vn1v1	309	5	the	the	DT
cord-278081-tk7vn1v1	309	6	inactive	inactive	JJ
cord-278081-tk7vn1v1	309	7	X	x	NN
cord-278081-tk7vn1v1	309	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	309	9	could	could	MD
cord-278081-tk7vn1v1	309	10	explain	explain	VB
cord-278081-tk7vn1v1	309	11	some	some	DT
cord-278081-tk7vn1v1	309	12	of	of	IN
cord-278081-tk7vn1v1	309	13	the	the	DT
cord-278081-tk7vn1v1	309	14	cases	case	NNS
cord-278081-tk7vn1v1	309	15	of	of	IN
cord-278081-tk7vn1v1	309	16	triple	triple	JJ
cord-278081-tk7vn1v1	309	17	-	-	HYPH
cord-278081-tk7vn1v1	309	18	negative	negative	JJ
cord-278081-tk7vn1v1	309	19	breast	breast	NN
cord-278081-tk7vn1v1	309	20	cancer	cancer	NN
cord-278081-tk7vn1v1	309	21	in	in	IN
cord-278081-tk7vn1v1	309	22	which	which	WDT
cord-278081-tk7vn1v1	309	23	there	there	EX
cord-278081-tk7vn1v1	309	24	is	be	VBZ
cord-278081-tk7vn1v1	309	25	no	no	DT
cord-278081-tk7vn1v1	309	26	overexpression	overexpression	NN
cord-278081-tk7vn1v1	309	27	of	of	IN
cord-278081-tk7vn1v1	309	28	HER2	HER2	NNP
cord-278081-tk7vn1v1	309	29	,	,	,
cord-278081-tk7vn1v1	309	30	estrogen	estrogen	NN
cord-278081-tk7vn1v1	309	31	,	,	,
cord-278081-tk7vn1v1	309	32	or	or	CC
cord-278081-tk7vn1v1	309	33	progesterone	progesterone	NN
cord-278081-tk7vn1v1	309	34	receptors	receptor	NNS
cord-278081-tk7vn1v1	309	35	(	(	-LRB-
cord-278081-tk7vn1v1	309	36	103	103	CD
cord-278081-tk7vn1v1	309	37	)	)	-RRB-
cord-278081-tk7vn1v1	309	38	.	.	.
cord-278081-tk7vn1v1	310	1	So	so	RB
cord-278081-tk7vn1v1	310	2	this	this	DT
cord-278081-tk7vn1v1	310	3	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	310	4	scenario	scenario	NN
cord-278081-tk7vn1v1	310	5	of	of	IN
cord-278081-tk7vn1v1	310	6	Barr	Barr	NNP
cord-278081-tk7vn1v1	310	7	body	body	NN
cord-278081-tk7vn1v1	310	8	disruption	disruption	NN
cord-278081-tk7vn1v1	310	9	could	could	MD
cord-278081-tk7vn1v1	310	10	explain	explain	VB
cord-278081-tk7vn1v1	310	11	some	some	DT
cord-278081-tk7vn1v1	310	12	of	of	IN
cord-278081-tk7vn1v1	310	13	the	the	DT
cord-278081-tk7vn1v1	310	14	enigmatic	enigmatic	JJ
cord-278081-tk7vn1v1	310	15	cases	case	NNS
cord-278081-tk7vn1v1	310	16	of	of	IN
cord-278081-tk7vn1v1	310	17	cancers	cancer	NNS
cord-278081-tk7vn1v1	310	18	.	.	.
cord-278081-tk7vn1v1	311	1	Also	also	RB
cord-278081-tk7vn1v1	311	2	,	,	,
cord-278081-tk7vn1v1	311	3	keep	keep	VB
cord-278081-tk7vn1v1	311	4	in	in	IN
cord-278081-tk7vn1v1	311	5	mind	mind	NN
cord-278081-tk7vn1v1	311	6	that	that	IN
cord-278081-tk7vn1v1	311	7	viral	viral	JJ
cord-278081-tk7vn1v1	311	8	disruption	disruption	NN
cord-278081-tk7vn1v1	311	9	of	of	IN
cord-278081-tk7vn1v1	311	10	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	311	11	could	could	MD
cord-278081-tk7vn1v1	311	12	interfere	interfere	VB
cord-278081-tk7vn1v1	311	13	with	with	IN
cord-278081-tk7vn1v1	311	14	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	311	15	involvement	involvement	NN
cord-278081-tk7vn1v1	311	16	in	in	IN
cord-278081-tk7vn1v1	311	17	DNA	dna	NN
cord-278081-tk7vn1v1	311	18	repair	repair	NN
cord-278081-tk7vn1v1	311	19	,	,	,
cord-278081-tk7vn1v1	311	20	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	311	21	assembly	assembly	NN
cord-278081-tk7vn1v1	311	22	of	of	IN
cord-278081-tk7vn1v1	311	23	centromeres	centromere	NNS
cord-278081-tk7vn1v1	311	24	,	,	,
cord-278081-tk7vn1v1	311	25	and	and	CC
cord-278081-tk7vn1v1	311	26	alter	alter	VB
cord-278081-tk7vn1v1	311	27	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	311	28	control	control	NN
cord-278081-tk7vn1v1	311	29	of	of	IN
cord-278081-tk7vn1v1	311	30	cell	cell	NN
cord-278081-tk7vn1v1	311	31	-	-	HYPH
cord-278081-tk7vn1v1	311	32	cycle	cycle	NN
cord-278081-tk7vn1v1	311	33	kinases	kinase	NNS
cord-278081-tk7vn1v1	311	34	(	(	-LRB-
cord-278081-tk7vn1v1	311	35	78	78	CD
cord-278081-tk7vn1v1	311	36	)	)	-RRB-
cord-278081-tk7vn1v1	311	37	.	.	.
cord-278081-tk7vn1v1	312	1	Fragmenting	fragment	VBG
cord-278081-tk7vn1v1	312	2	of	of	IN
cord-278081-tk7vn1v1	312	3	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	312	4	as	as	IN
cord-278081-tk7vn1v1	312	5	centromeres	centromere	NNS
cord-278081-tk7vn1v1	312	6	are	be	VBP
cord-278081-tk7vn1v1	312	7	being	be	VBG
cord-278081-tk7vn1v1	312	8	formed	form	VBN
cord-278081-tk7vn1v1	312	9	could	could	MD
cord-278081-tk7vn1v1	312	10	lead	lead	VB
cord-278081-tk7vn1v1	312	11	to	to	IN
cord-278081-tk7vn1v1	312	12	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	312	13	distribution	distribution	NN
cord-278081-tk7vn1v1	312	14	of	of	IN
cord-278081-tk7vn1v1	312	15	chromosomes	chromosome	NNS
cord-278081-tk7vn1v1	312	16	resulting	result	VBG
cord-278081-tk7vn1v1	312	17	in	in	IN
cord-278081-tk7vn1v1	312	18	daughter	daughter	NN
cord-278081-tk7vn1v1	312	19	cells	cell	NNS
cord-278081-tk7vn1v1	312	20	of	of	IN
cord-278081-tk7vn1v1	312	21	differing	differ	VBG
cord-278081-tk7vn1v1	312	22	karyotypes	karyotype	NNS
cord-278081-tk7vn1v1	312	23	,	,	,
cord-278081-tk7vn1v1	312	24	such	such	JJ
cord-278081-tk7vn1v1	312	25	as	as	IN
cord-278081-tk7vn1v1	312	26	a	a	DT
cord-278081-tk7vn1v1	312	27	parent	parent	NN
cord-278081-tk7vn1v1	312	28	(	(	-LRB-
cord-278081-tk7vn1v1	312	29	46,XX	46,xx	CD
cord-278081-tk7vn1v1	312	30	)	)	-RRB-
cord-278081-tk7vn1v1	312	31	cell	cell	NN
cord-278081-tk7vn1v1	312	32	generating	generating	NN
cord-278081-tk7vn1v1	312	33	daughter	daughter	NN
cord-278081-tk7vn1v1	312	34	cells	cell	NNS
cord-278081-tk7vn1v1	312	35	of	of	IN
cord-278081-tk7vn1v1	312	36	(	(	-LRB-
cord-278081-tk7vn1v1	312	37	45,X0	45,x0	CD
cord-278081-tk7vn1v1	312	38	)	)	-RRB-
cord-278081-tk7vn1v1	313	1	and	and	CC
cord-278081-tk7vn1v1	313	2	(	(	-LRB-
cord-278081-tk7vn1v1	313	3	47	47	CD
cord-278081-tk7vn1v1	313	4	,	,	,
cord-278081-tk7vn1v1	313	5	XXX	XXX	NNP
cord-278081-tk7vn1v1	313	6	)	)	-RRB-
cord-278081-tk7vn1v1	313	7	.	.	.
cord-278081-tk7vn1v1	314	1	Disruption	disruption	NN
cord-278081-tk7vn1v1	314	2	of	of	IN
cord-278081-tk7vn1v1	314	3	the	the	DT
cord-278081-tk7vn1v1	314	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	314	5	in	in	IN
cord-278081-tk7vn1v1	314	6	tumor	tumor	NN
cord-278081-tk7vn1v1	314	7	cells	cell	NNS
cord-278081-tk7vn1v1	314	8	could	could	MD
cord-278081-tk7vn1v1	314	9	also	also	RB
cord-278081-tk7vn1v1	314	10	lead	lead	VB
cord-278081-tk7vn1v1	314	11	to	to	IN
cord-278081-tk7vn1v1	314	12	appearance	appearance	NN
cord-278081-tk7vn1v1	314	13	of	of	IN
cord-278081-tk7vn1v1	314	14	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	314	15	.	.	.
cord-278081-tk7vn1v1	315	1	Autoantigens	Autoantigens	NNP
cord-278081-tk7vn1v1	315	2	can	can	MD
cord-278081-tk7vn1v1	315	3	arise	arise	VB
cord-278081-tk7vn1v1	315	4	in	in	IN
cord-278081-tk7vn1v1	315	5	cancers	cancer	NNS
cord-278081-tk7vn1v1	315	6	but	but	CC
cord-278081-tk7vn1v1	315	7	they	-PRON-	PRP
cord-278081-tk7vn1v1	315	8	differ	differ	VBP
cord-278081-tk7vn1v1	315	9	from	from	IN
cord-278081-tk7vn1v1	315	10	those	those	DT
cord-278081-tk7vn1v1	315	11	normally	normally	RB
cord-278081-tk7vn1v1	315	12	seen	see	VBN
cord-278081-tk7vn1v1	315	13	in	in	IN
cord-278081-tk7vn1v1	315	14	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	315	15	diseases	disease	NNS
cord-278081-tk7vn1v1	315	16	such	such	JJ
cord-278081-tk7vn1v1	315	17	as	as	IN
cord-278081-tk7vn1v1	315	18	SLE	SLE	NNP
cord-278081-tk7vn1v1	315	19	.	.	.
cord-278081-tk7vn1v1	316	1	The	the	DT
cord-278081-tk7vn1v1	316	2	differences	difference	NNS
cord-278081-tk7vn1v1	316	3	could	could	MD
cord-278081-tk7vn1v1	316	4	arise	arise	VB
cord-278081-tk7vn1v1	316	5	from	from	IN
cord-278081-tk7vn1v1	316	6	:	:	:
cord-278081-tk7vn1v1	316	7	the	the	DT
cord-278081-tk7vn1v1	316	8	cell	cell	NN
cord-278081-tk7vn1v1	316	9	type	type	NN
cord-278081-tk7vn1v1	316	10	involved	involve	VBN
cord-278081-tk7vn1v1	316	11	(	(	-LRB-
cord-278081-tk7vn1v1	316	12	proliferating	proliferate	VBG
cord-278081-tk7vn1v1	316	13	versus	versus	IN
cord-278081-tk7vn1v1	316	14	mature	mature	JJ
cord-278081-tk7vn1v1	316	15	,	,	,
cord-278081-tk7vn1v1	316	16	differentiated	differentiated	JJ
cord-278081-tk7vn1v1	316	17	)	)	-RRB-
cord-278081-tk7vn1v1	316	18	;	;	:
cord-278081-tk7vn1v1	316	19	the	the	DT
cord-278081-tk7vn1v1	316	20	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	316	21	activity	activity	NN
cord-278081-tk7vn1v1	316	22	and	and	CC
cord-278081-tk7vn1v1	316	23	content	content	NN
cord-278081-tk7vn1v1	316	24	at	at	IN
cord-278081-tk7vn1v1	316	25	the	the	DT
cord-278081-tk7vn1v1	316	26	time	time	NN
cord-278081-tk7vn1v1	316	27	of	of	IN
cord-278081-tk7vn1v1	316	28	disruption	disruption	NN
cord-278081-tk7vn1v1	316	29	;	;	:
cord-278081-tk7vn1v1	316	30	and	and	CC
cord-278081-tk7vn1v1	316	31	the	the	DT
cord-278081-tk7vn1v1	316	32	rapidity	rapidity	NN
cord-278081-tk7vn1v1	316	33	of	of	IN
cord-278081-tk7vn1v1	316	34	the	the	DT
cord-278081-tk7vn1v1	316	35	disruption	disruption	NN
cord-278081-tk7vn1v1	316	36	(	(	-LRB-
cord-278081-tk7vn1v1	316	37	acute	acute	JJ
cord-278081-tk7vn1v1	316	38	versus	versus	IN
cord-278081-tk7vn1v1	316	39	gradual	gradual	JJ
cord-278081-tk7vn1v1	316	40	accumulation	accumulation	NN
cord-278081-tk7vn1v1	316	41	)	)	-RRB-
cord-278081-tk7vn1v1	316	42	.	.	.
cord-278081-tk7vn1v1	317	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	317	2	can	can	MD
cord-278081-tk7vn1v1	317	3	consider	consider	VB
cord-278081-tk7vn1v1	317	4	that	that	IN
cord-278081-tk7vn1v1	317	5	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	317	6	in	in	IN
cord-278081-tk7vn1v1	317	7	proliferating	proliferate	VBG
cord-278081-tk7vn1v1	317	8	cells	cell	NNS
cord-278081-tk7vn1v1	317	9	would	would	MD
cord-278081-tk7vn1v1	317	10	be	be	VB
cord-278081-tk7vn1v1	317	11	heavily	heavily	RB
cord-278081-tk7vn1v1	317	12	involved	involve	VBN
cord-278081-tk7vn1v1	317	13	in	in	IN
cord-278081-tk7vn1v1	317	14	cell	cell	NN
cord-278081-tk7vn1v1	317	15	cycling	cycling	NN
cord-278081-tk7vn1v1	317	16	,	,	,
cord-278081-tk7vn1v1	317	17	such	such	JJ
cord-278081-tk7vn1v1	317	18	as	as	IN
cord-278081-tk7vn1v1	317	19	generating	generate	VBG
cord-278081-tk7vn1v1	317	20	centromere	centromere	NN
cord-278081-tk7vn1v1	317	21	components	component	NNS
cord-278081-tk7vn1v1	317	22	,	,	,
cord-278081-tk7vn1v1	317	23	and	and	CC
cord-278081-tk7vn1v1	317	24	so	so	RB
cord-278081-tk7vn1v1	317	25	many	many	JJ
cord-278081-tk7vn1v1	317	26	of	of	IN
cord-278081-tk7vn1v1	317	27	the	the	DT
cord-278081-tk7vn1v1	317	28	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	317	29	that	that	WDT
cord-278081-tk7vn1v1	317	30	arise	arise	VBP
cord-278081-tk7vn1v1	317	31	would	would	MD
cord-278081-tk7vn1v1	317	32	be	be	VB
cord-278081-tk7vn1v1	317	33	expected	expect	VBN
cord-278081-tk7vn1v1	317	34	to	to	TO
cord-278081-tk7vn1v1	317	35	be	be	VB
cord-278081-tk7vn1v1	317	36	related	relate	VBN
cord-278081-tk7vn1v1	317	37	to	to	IN
cord-278081-tk7vn1v1	317	38	cell	cell	NN
cord-278081-tk7vn1v1	317	39	cycling	cycling	NN
cord-278081-tk7vn1v1	317	40	and	and	CC
cord-278081-tk7vn1v1	317	41	suppression	suppression	NN
cord-278081-tk7vn1v1	317	42	of	of	IN
cord-278081-tk7vn1v1	317	43	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	317	44	(	(	-LRB-
cord-278081-tk7vn1v1	317	45	104	104	CD
cord-278081-tk7vn1v1	317	46	)	)	-RRB-
cord-278081-tk7vn1v1	317	47	.	.	.
cord-278081-tk7vn1v1	318	1	Autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	318	2	diseases	disease	NNS
cord-278081-tk7vn1v1	318	3	,	,	,
cord-278081-tk7vn1v1	318	4	such	such	JJ
cord-278081-tk7vn1v1	318	5	as	as	IN
cord-278081-tk7vn1v1	318	6	SLE	SLE	NNP
cord-278081-tk7vn1v1	318	7	,	,	,
cord-278081-tk7vn1v1	318	8	give	give	VBP
cord-278081-tk7vn1v1	318	9	rise	rise	NN
cord-278081-tk7vn1v1	318	10	to	to	IN
cord-278081-tk7vn1v1	318	11	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	318	12	that	that	WDT
cord-278081-tk7vn1v1	318	13	are	be	VBP
cord-278081-tk7vn1v1	318	14	components	component	NNS
cord-278081-tk7vn1v1	318	15	more	more	RBR
cord-278081-tk7vn1v1	318	16	routinely	routinely	RB
cord-278081-tk7vn1v1	318	17	found	find	VBN
cord-278081-tk7vn1v1	318	18	in	in	IN
cord-278081-tk7vn1v1	318	19	abundance	abundance	NN
cord-278081-tk7vn1v1	318	20	in	in	IN
cord-278081-tk7vn1v1	318	21	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	318	22	,	,	,
cord-278081-tk7vn1v1	318	23	such	such	JJ
cord-278081-tk7vn1v1	318	24	as	as	IN
cord-278081-tk7vn1v1	318	25	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	318	26	or	or	CC
cord-278081-tk7vn1v1	318	27	splicosomal	splicosomal	JJ
cord-278081-tk7vn1v1	318	28	components	component	NNS
cord-278081-tk7vn1v1	318	29	.	.	.
cord-278081-tk7vn1v1	319	1	There	there	EX
cord-278081-tk7vn1v1	319	2	is	be	VBZ
cord-278081-tk7vn1v1	319	3	a	a	DT
cord-278081-tk7vn1v1	319	4	slightly	slightly	RB
cord-278081-tk7vn1v1	319	5	higher	high	JJR
cord-278081-tk7vn1v1	319	6	risk	risk	NN
cord-278081-tk7vn1v1	319	7	of	of	IN
cord-278081-tk7vn1v1	319	8	cancers	cancer	NNS
cord-278081-tk7vn1v1	319	9	among	among	IN
cord-278081-tk7vn1v1	319	10	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	319	11	patients	patient	NNS
cord-278081-tk7vn1v1	319	12	but	but	CC
cord-278081-tk7vn1v1	319	13	the	the	DT
cord-278081-tk7vn1v1	319	14	risk	risk	NN
cord-278081-tk7vn1v1	319	15	varies	vary	VBZ
cord-278081-tk7vn1v1	319	16	with	with	IN
cord-278081-tk7vn1v1	319	17	regards	regard	NNS
cord-278081-tk7vn1v1	319	18	to	to	IN
cord-278081-tk7vn1v1	319	19	the	the	DT
cord-278081-tk7vn1v1	319	20	type	type	NN
cord-278081-tk7vn1v1	319	21	of	of	IN
cord-278081-tk7vn1v1	319	22	cancer	cancer	NN
cord-278081-tk7vn1v1	319	23	(	(	-LRB-
cord-278081-tk7vn1v1	319	24	105	105	CD
cord-278081-tk7vn1v1	319	25	)	)	-RRB-
cord-278081-tk7vn1v1	319	26	.	.	.
cord-278081-tk7vn1v1	320	1	Therapeutics	therapeutic	NNS
cord-278081-tk7vn1v1	320	2	taken	take	VBN
cord-278081-tk7vn1v1	320	3	by	by	IN
cord-278081-tk7vn1v1	320	4	the	the	DT
cord-278081-tk7vn1v1	320	5	patient	patient	NN
cord-278081-tk7vn1v1	320	6	targeting	target	VBG
cord-278081-tk7vn1v1	320	7	the	the	DT
cord-278081-tk7vn1v1	320	8	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	320	9	disease	disease	NN
cord-278081-tk7vn1v1	320	10	could	could	MD
cord-278081-tk7vn1v1	320	11	contribute	contribute	VB
cord-278081-tk7vn1v1	320	12	to	to	IN
cord-278081-tk7vn1v1	320	13	cancer	cancer	NN
cord-278081-tk7vn1v1	320	14	development	development	NN
cord-278081-tk7vn1v1	320	15	.	.	.
cord-278081-tk7vn1v1	321	1	Hematological	Hematological	NNP
cord-278081-tk7vn1v1	321	2	,	,	,
cord-278081-tk7vn1v1	321	3	thyroid	thyroid	NN
cord-278081-tk7vn1v1	321	4	,	,	,
cord-278081-tk7vn1v1	321	5	lung	lung	NN
cord-278081-tk7vn1v1	321	6	,	,	,
cord-278081-tk7vn1v1	321	7	and	and	CC
cord-278081-tk7vn1v1	321	8	vulva	vulva	NN
cord-278081-tk7vn1v1	321	9	cancers	cancer	NNS
cord-278081-tk7vn1v1	321	10	show	show	VBP
cord-278081-tk7vn1v1	321	11	an	an	DT
cord-278081-tk7vn1v1	321	12	increased	increase	VBN
cord-278081-tk7vn1v1	321	13	risk	risk	NN
cord-278081-tk7vn1v1	321	14	with	with	IN
cord-278081-tk7vn1v1	321	15	non	non	JJ
cord-278081-tk7vn1v1	321	16	-	-	JJ
cord-278081-tk7vn1v1	321	17	Hodgkin	Hodgkin	NNP
cord-278081-tk7vn1v1	321	18	's	's	POS
cord-278081-tk7vn1v1	321	19	lymphoma	lymphoma	NN
cord-278081-tk7vn1v1	321	20	showing	show	VBG
cord-278081-tk7vn1v1	321	21	a	a	DT
cord-278081-tk7vn1v1	321	22	3×	3×	CD
cord-278081-tk7vn1v1	321	23	to	to	IN
cord-278081-tk7vn1v1	321	24	4×	4×	CD
cord-278081-tk7vn1v1	321	25	greater	great	JJR
cord-278081-tk7vn1v1	321	26	risk	risk	NN
cord-278081-tk7vn1v1	321	27	in	in	IN
cord-278081-tk7vn1v1	321	28	lupus	lupus	NN
cord-278081-tk7vn1v1	321	29	patients	patient	NNS
cord-278081-tk7vn1v1	321	30	,	,	,
cord-278081-tk7vn1v1	321	31	while	while	IN
cord-278081-tk7vn1v1	321	32	breast	breast	NN
cord-278081-tk7vn1v1	321	33	,	,	,
cord-278081-tk7vn1v1	321	34	endometrial	endometrial	NN
cord-278081-tk7vn1v1	321	35	,	,	,
cord-278081-tk7vn1v1	321	36	and	and	CC
cord-278081-tk7vn1v1	321	37	ovarian	ovarian	JJ
cord-278081-tk7vn1v1	321	38	cancers	cancer	NNS
cord-278081-tk7vn1v1	321	39	show	show	VBP
cord-278081-tk7vn1v1	321	40	a	a	DT
cord-278081-tk7vn1v1	321	41	lower	low	JJR
cord-278081-tk7vn1v1	321	42	risk	risk	NN
cord-278081-tk7vn1v1	321	43	.	.	.
cord-278081-tk7vn1v1	322	1	For	for	IN
cord-278081-tk7vn1v1	322	2	now	now	RB
cord-278081-tk7vn1v1	322	3	there	there	EX
cord-278081-tk7vn1v1	322	4	is	be	VBZ
cord-278081-tk7vn1v1	322	5	no	no	DT
cord-278081-tk7vn1v1	322	6	direct	direct	JJ
cord-278081-tk7vn1v1	322	7	connection	connection	NN
cord-278081-tk7vn1v1	322	8	between	between	IN
cord-278081-tk7vn1v1	322	9	viruses	virus	NNS
cord-278081-tk7vn1v1	322	10	and	and	CC
cord-278081-tk7vn1v1	322	11	the	the	DT
cord-278081-tk7vn1v1	322	12	"	"	``
cord-278081-tk7vn1v1	322	13	X	x	NN
cord-278081-tk7vn1v1	322	14	chromosome	chromosome	NN
cord-278081-tk7vn1v1	322	15	-	-	HYPH
cord-278081-tk7vn1v1	322	16	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	322	17	nexus	nexus	NN
cord-278081-tk7vn1v1	322	18	"	"	''
cord-278081-tk7vn1v1	322	19	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	322	20	to	to	IN
cord-278081-tk7vn1v1	322	21	the	the	DT
cord-278081-tk7vn1v1	322	22	increased	increase	VBN
cord-278081-tk7vn1v1	322	23	risk	risk	NN
cord-278081-tk7vn1v1	322	24	of	of	IN
cord-278081-tk7vn1v1	322	25	cancers	cancer	NNS
cord-278081-tk7vn1v1	322	26	among	among	IN
cord-278081-tk7vn1v1	322	27	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	322	28	disease	disease	NN
cord-278081-tk7vn1v1	322	29	patients	patient	NNS
cord-278081-tk7vn1v1	322	30	but	but	CC
cord-278081-tk7vn1v1	322	31	we	-PRON-	PRP
cord-278081-tk7vn1v1	322	32	can	can	MD
cord-278081-tk7vn1v1	322	33	consider	consider	VB
cord-278081-tk7vn1v1	322	34	the	the	DT
cord-278081-tk7vn1v1	322	35	induction	induction	NN
cord-278081-tk7vn1v1	322	36	by	by	IN
cord-278081-tk7vn1v1	322	37	viruses	virus	NNS
cord-278081-tk7vn1v1	322	38	of	of	IN
cord-278081-tk7vn1v1	322	39	increased	increase	VBN
cord-278081-tk7vn1v1	322	40	polyamine	polyamine	NN
cord-278081-tk7vn1v1	322	41	levels	level	NNS
cord-278081-tk7vn1v1	322	42	and	and	CC
cord-278081-tk7vn1v1	322	43	the	the	DT
cord-278081-tk7vn1v1	322	44	possible	possible	JJ
cord-278081-tk7vn1v1	322	45	reactivation	reactivation	NN
cord-278081-tk7vn1v1	322	46	of	of	IN
cord-278081-tk7vn1v1	322	47	X	x	NN
cord-278081-tk7vn1v1	322	48	-	-	HYPH
cord-278081-tk7vn1v1	322	49	linked	link	VBN
cord-278081-tk7vn1v1	322	50	polyamine	polyamine	NN
cord-278081-tk7vn1v1	322	51	genes	gene	NNS
cord-278081-tk7vn1v1	322	52	as	as	IN
cord-278081-tk7vn1v1	322	53	means	mean	NNS
cord-278081-tk7vn1v1	322	54	by	by	IN
cord-278081-tk7vn1v1	322	55	which	which	WDT
cord-278081-tk7vn1v1	322	56	competition	competition	NN
cord-278081-tk7vn1v1	322	57	for	for	IN
cord-278081-tk7vn1v1	322	58	the	the	DT
cord-278081-tk7vn1v1	322	59	cellular	cellular	JJ
cord-278081-tk7vn1v1	322	60	methyl	methyl	NN
cord-278081-tk7vn1v1	322	61	donor	donor	NN
cord-278081-tk7vn1v1	322	62	,	,	,
cord-278081-tk7vn1v1	322	63	SAM	SAM	NNP
cord-278081-tk7vn1v1	322	64	,	,	,
cord-278081-tk7vn1v1	322	65	could	could	MD
cord-278081-tk7vn1v1	322	66	reduce	reduce	VB
cord-278081-tk7vn1v1	322	67	DNA	dna	NN
cord-278081-tk7vn1v1	322	68	methylation	methylation	NN
cord-278081-tk7vn1v1	322	69	and	and	CC
cord-278081-tk7vn1v1	322	70	open	open	JJ
cord-278081-tk7vn1v1	322	71	oncogenes	oncogene	NNS
cord-278081-tk7vn1v1	322	72	for	for	IN
cord-278081-tk7vn1v1	322	73	overexpression	overexpression	NN
cord-278081-tk7vn1v1	322	74	in	in	IN
cord-278081-tk7vn1v1	322	75	proliferation	proliferation	NN
cord-278081-tk7vn1v1	322	76	competent	competent	JJ
cord-278081-tk7vn1v1	322	77	cells	cell	NNS
cord-278081-tk7vn1v1	322	78	.	.	.
cord-278081-tk7vn1v1	323	1	Increased	increase	VBN
cord-278081-tk7vn1v1	323	2	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	323	3	size	size	NN
cord-278081-tk7vn1v1	323	4	due	due	IN
cord-278081-tk7vn1v1	323	5	to	to	IN
cord-278081-tk7vn1v1	323	6	increased	increase	VBN
cord-278081-tk7vn1v1	323	7	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	323	8	could	could	MD
cord-278081-tk7vn1v1	323	9	add	add	VB
cord-278081-tk7vn1v1	323	10	to	to	IN
cord-278081-tk7vn1v1	323	11	the	the	DT
cord-278081-tk7vn1v1	323	12	disruption	disruption	NN
cord-278081-tk7vn1v1	323	13	of	of	IN
cord-278081-tk7vn1v1	323	14	neighboring	neighbor	VBG
cord-278081-tk7vn1v1	323	15	epigenetically	epigenetically	RB
cord-278081-tk7vn1v1	323	16	silenced	silence	VBN
cord-278081-tk7vn1v1	323	17	chromatin	chromatin	NN
cord-278081-tk7vn1v1	323	18	to	to	TO
cord-278081-tk7vn1v1	323	19	expose	expose	VB
cord-278081-tk7vn1v1	323	20	alleles	allele	NNS
cord-278081-tk7vn1v1	323	21	for	for	IN
cord-278081-tk7vn1v1	323	22	expression	expression	NN
cord-278081-tk7vn1v1	323	23	.	.	.
cord-278081-tk7vn1v1	324	1	The	the	DT
cord-278081-tk7vn1v1	324	2	focus	focus	NN
cord-278081-tk7vn1v1	324	3	of	of	IN
cord-278081-tk7vn1v1	324	4	this	this	DT
cord-278081-tk7vn1v1	324	5	discussion	discussion	NN
cord-278081-tk7vn1v1	324	6	has	have	VBZ
cord-278081-tk7vn1v1	324	7	been	be	VBN
cord-278081-tk7vn1v1	324	8	on	on	IN
cord-278081-tk7vn1v1	324	9	viruses	virus	NNS
cord-278081-tk7vn1v1	324	10	and	and	CC
cord-278081-tk7vn1v1	324	11	the	the	DT
cord-278081-tk7vn1v1	324	12	"	"	``
cord-278081-tk7vn1v1	324	13	X	x	NN
cord-278081-tk7vn1v1	324	14	chromosome	chromosome	NN
cord-278081-tk7vn1v1	324	15	-	-	HYPH
cord-278081-tk7vn1v1	324	16	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	324	17	nexus	nexus	NN
cord-278081-tk7vn1v1	324	18	"	"	''
cord-278081-tk7vn1v1	324	19	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	324	20	since	since	IN
cord-278081-tk7vn1v1	324	21	we	-PRON-	PRP
cord-278081-tk7vn1v1	324	22	now	now	RB
cord-278081-tk7vn1v1	324	23	understand	understand	VBP
cord-278081-tk7vn1v1	324	24	the	the	DT
cord-278081-tk7vn1v1	324	25	effects	effect	NNS
cord-278081-tk7vn1v1	324	26	a	a	DT
cord-278081-tk7vn1v1	324	27	virus	virus	NN
cord-278081-tk7vn1v1	324	28	can	can	MD
cord-278081-tk7vn1v1	324	29	have	have	VB
cord-278081-tk7vn1v1	324	30	on	on	IN
cord-278081-tk7vn1v1	324	31	the	the	DT
cord-278081-tk7vn1v1	324	32	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	324	33	and	and	CC
cord-278081-tk7vn1v1	324	34	how	how	WRB
cord-278081-tk7vn1v1	324	35	it	-PRON-	PRP
cord-278081-tk7vn1v1	324	36	is	be	VBZ
cord-278081-tk7vn1v1	324	37	to	to	IN
cord-278081-tk7vn1v1	324	38	the	the	DT
cord-278081-tk7vn1v1	324	39	benefit	benefit	NN
cord-278081-tk7vn1v1	324	40	of	of	IN
cord-278081-tk7vn1v1	324	41	the	the	DT
cord-278081-tk7vn1v1	324	42	virus	virus	NN
cord-278081-tk7vn1v1	324	43	to	to	TO
cord-278081-tk7vn1v1	324	44	influence	influence	VB
cord-278081-tk7vn1v1	324	45	the	the	DT
cord-278081-tk7vn1v1	324	46	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	324	47	activity	activity	NN
cord-278081-tk7vn1v1	324	48	.	.	.
cord-278081-tk7vn1v1	325	1	And	and	CC
cord-278081-tk7vn1v1	325	2	EBV	EBV	NNP
cord-278081-tk7vn1v1	325	3	has	have	VBZ
cord-278081-tk7vn1v1	325	4	been	be	VBN
cord-278081-tk7vn1v1	325	5	used	use	VBN
cord-278081-tk7vn1v1	325	6	as	as	IN
cord-278081-tk7vn1v1	325	7	the	the	DT
cord-278081-tk7vn1v1	325	8	primary	primary	JJ
cord-278081-tk7vn1v1	325	9	example	example	NN
cord-278081-tk7vn1v1	325	10	of	of	IN
cord-278081-tk7vn1v1	325	11	viral	viral	JJ
cord-278081-tk7vn1v1	325	12	involvement	involvement	NN
cord-278081-tk7vn1v1	325	13	in	in	IN
cord-278081-tk7vn1v1	325	14	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	325	15	diseases	disease	NNS
cord-278081-tk7vn1v1	325	16	since	since	IN
cord-278081-tk7vn1v1	325	17	it	-PRON-	PRP
cord-278081-tk7vn1v1	325	18	is	be	VBZ
cord-278081-tk7vn1v1	325	19	one	one	CD
cord-278081-tk7vn1v1	325	20	of	of	IN
cord-278081-tk7vn1v1	325	21	the	the	DT
cord-278081-tk7vn1v1	325	22	viruses	virus	NNS
cord-278081-tk7vn1v1	325	23	most	most	RBS
cord-278081-tk7vn1v1	325	24	suspected	suspect	VBN
cord-278081-tk7vn1v1	325	25	of	of	IN
cord-278081-tk7vn1v1	325	26	having	have	VBG
cord-278081-tk7vn1v1	325	27	such	such	PDT
cord-278081-tk7vn1v1	325	28	a	a	DT
cord-278081-tk7vn1v1	325	29	role	role	NN
cord-278081-tk7vn1v1	325	30	and	and	CC
cord-278081-tk7vn1v1	325	31	we	-PRON-	PRP
cord-278081-tk7vn1v1	325	32	can	can	MD
cord-278081-tk7vn1v1	325	33	connect	connect	VB
cord-278081-tk7vn1v1	325	34	EBV	EBV	NNP
cord-278081-tk7vn1v1	325	35	actions	action	NNS
cord-278081-tk7vn1v1	325	36	(	(	-LRB-
cord-278081-tk7vn1v1	325	37	e.g.	e.g.	RB
cord-278081-tk7vn1v1	325	38	,	,	,
cord-278081-tk7vn1v1	325	39	increased	increase	VBN
cord-278081-tk7vn1v1	325	40	MYC	MYC	NNP
cord-278081-tk7vn1v1	325	41	activity	activity	NN
cord-278081-tk7vn1v1	325	42	)	)	-RRB-
cord-278081-tk7vn1v1	325	43	to	to	IN
cord-278081-tk7vn1v1	325	44	increases	increase	NNS
cord-278081-tk7vn1v1	325	45	in	in	IN
cord-278081-tk7vn1v1	325	46	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	325	47	that	that	WDT
cord-278081-tk7vn1v1	325	48	could	could	MD
cord-278081-tk7vn1v1	325	49	directly	directly	RB
cord-278081-tk7vn1v1	325	50	impact	impact	VB
cord-278081-tk7vn1v1	325	51	the	the	DT
cord-278081-tk7vn1v1	325	52	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	325	53	and	and	CC
cord-278081-tk7vn1v1	325	54	trigger	trigger	VB
cord-278081-tk7vn1v1	325	55	the	the	DT
cord-278081-tk7vn1v1	325	56	hypothesized	hypothesize	VBN
cord-278081-tk7vn1v1	325	57	mechanism	mechanism	NN
cord-278081-tk7vn1v1	325	58	.	.	.
cord-278081-tk7vn1v1	326	1	Other	other	JJ
cord-278081-tk7vn1v1	326	2	factors	factor	NNS
cord-278081-tk7vn1v1	326	3	besides	besides	IN
cord-278081-tk7vn1v1	326	4	viruses	virus	NNS
cord-278081-tk7vn1v1	326	5	,	,	,
cord-278081-tk7vn1v1	326	6	such	such	JJ
cord-278081-tk7vn1v1	326	7	as	as	IN
cord-278081-tk7vn1v1	326	8	bacteria	bacteria	NNS
cord-278081-tk7vn1v1	326	9	or	or	CC
cord-278081-tk7vn1v1	326	10	chemicals	chemical	NNS
cord-278081-tk7vn1v1	326	11	,	,	,
cord-278081-tk7vn1v1	326	12	can	can	MD
cord-278081-tk7vn1v1	326	13	contribute	contribute	VB
cord-278081-tk7vn1v1	326	14	to	to	IN
cord-278081-tk7vn1v1	326	15	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	326	16	diseases	disease	NNS
cord-278081-tk7vn1v1	326	17	but	but	CC
cord-278081-tk7vn1v1	326	18	the	the	DT
cord-278081-tk7vn1v1	326	19	means	mean	NNS
cord-278081-tk7vn1v1	326	20	is	be	VBZ
cord-278081-tk7vn1v1	326	21	less	less	RBR
cord-278081-tk7vn1v1	326	22	clear	clear	JJ
cord-278081-tk7vn1v1	326	23	and	and	CC
cord-278081-tk7vn1v1	326	24	may	may	MD
cord-278081-tk7vn1v1	326	25	not	not	RB
cord-278081-tk7vn1v1	326	26	closely	closely	RB
cord-278081-tk7vn1v1	326	27	follow	follow	VB
cord-278081-tk7vn1v1	326	28	the	the	DT
cord-278081-tk7vn1v1	326	29	mechanism	mechanism	NN
cord-278081-tk7vn1v1	326	30	proposed	propose	VBN
cord-278081-tk7vn1v1	326	31	.	.	.
cord-278081-tk7vn1v1	327	1	Bacteria	Bacteria	NNS
cord-278081-tk7vn1v1	327	2	,	,	,
cord-278081-tk7vn1v1	327	3	for	for	IN
cord-278081-tk7vn1v1	327	4	example	example	NN
cord-278081-tk7vn1v1	327	5	,	,	,
cord-278081-tk7vn1v1	327	6	produce	produce	VBP
cord-278081-tk7vn1v1	327	7	putrescine	putrescine	NN
cord-278081-tk7vn1v1	327	8	and	and	CC
cord-278081-tk7vn1v1	327	9	spermidine	spermidine	NN
cord-278081-tk7vn1v1	327	10	without	without	IN
cord-278081-tk7vn1v1	327	11	the	the	DT
cord-278081-tk7vn1v1	327	12	extensive	extensive	JJ
cord-278081-tk7vn1v1	327	13	controls	control	NNS
cord-278081-tk7vn1v1	327	14	on	on	IN
cord-278081-tk7vn1v1	327	15	polyamine	polyamine	NN
cord-278081-tk7vn1v1	327	16	synthesis	synthesis	NN
cord-278081-tk7vn1v1	327	17	seen	see	VBN
cord-278081-tk7vn1v1	327	18	in	in	IN
cord-278081-tk7vn1v1	327	19	eukaryotes	eukaryote	NNS
cord-278081-tk7vn1v1	327	20	but	but	CC
cord-278081-tk7vn1v1	327	21	the	the	DT
cord-278081-tk7vn1v1	327	22	bacteria	bacteria	NNS
cord-278081-tk7vn1v1	327	23	can	can	MD
cord-278081-tk7vn1v1	327	24	produce	produce	VB
cord-278081-tk7vn1v1	327	25	their	-PRON-	PRP$
cord-278081-tk7vn1v1	327	26	own	own	JJ
cord-278081-tk7vn1v1	327	27	machinery	machinery	NN
cord-278081-tk7vn1v1	327	28	and	and	CC
cord-278081-tk7vn1v1	327	29	are	be	VBP
cord-278081-tk7vn1v1	327	30	not	not	RB
cord-278081-tk7vn1v1	327	31	as	as	RB
cord-278081-tk7vn1v1	327	32	dependent	dependent	JJ
cord-278081-tk7vn1v1	327	33	as	as	IN
cord-278081-tk7vn1v1	327	34	viruses	virus	NNS
cord-278081-tk7vn1v1	327	35	on	on	IN
cord-278081-tk7vn1v1	327	36	the	the	DT
cord-278081-tk7vn1v1	327	37	cell	cell	NN
cord-278081-tk7vn1v1	327	38	's	's	POS
cord-278081-tk7vn1v1	327	39	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	327	40	.	.	.
cord-278081-tk7vn1v1	328	1	In	in	IN
cord-278081-tk7vn1v1	328	2	addition	addition	NN
cord-278081-tk7vn1v1	328	3	,	,	,
cord-278081-tk7vn1v1	328	4	disruption	disruption	NN
cord-278081-tk7vn1v1	328	5	of	of	IN
cord-278081-tk7vn1v1	328	6	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	328	7	,	,	,
cord-278081-tk7vn1v1	328	8	such	such	JJ
cord-278081-tk7vn1v1	328	9	as	as	IN
cord-278081-tk7vn1v1	328	10	the	the	DT
cord-278081-tk7vn1v1	328	11	inactive	inactive	JJ
cord-278081-tk7vn1v1	328	12	X	x	NN
cord-278081-tk7vn1v1	328	13	chromosome	chromosome	NN
cord-278081-tk7vn1v1	328	14	,	,	,
cord-278081-tk7vn1v1	328	15	can	can	MD
cord-278081-tk7vn1v1	328	16	open	open	VB
cord-278081-tk7vn1v1	328	17	latent	latent	JJ
cord-278081-tk7vn1v1	328	18	viruses	virus	NNS
cord-278081-tk7vn1v1	328	19	.	.	.
cord-278081-tk7vn1v1	329	1	The	the	DT
cord-278081-tk7vn1v1	329	2	X	x	NN
cord-278081-tk7vn1v1	329	3	chromosome	chromosome	NN
cord-278081-tk7vn1v1	329	4	has	have	VBZ
cord-278081-tk7vn1v1	329	5	four	four	CD
cord-278081-tk7vn1v1	329	6	major	major	JJ
cord-278081-tk7vn1v1	329	7	fragile	fragile	JJ
cord-278081-tk7vn1v1	329	8	sites	site	NNS
cord-278081-tk7vn1v1	329	9	and	and	CC
cord-278081-tk7vn1v1	329	10	fragile	fragile	JJ
cord-278081-tk7vn1v1	329	11	sites	site	NNS
cord-278081-tk7vn1v1	329	12	are	be	VBP
cord-278081-tk7vn1v1	329	13	frequently	frequently	RB
cord-278081-tk7vn1v1	329	14	the	the	DT
cord-278081-tk7vn1v1	329	15	locations	location	NNS
cord-278081-tk7vn1v1	329	16	chosen	choose	VBN
cord-278081-tk7vn1v1	329	17	for	for	IN
cord-278081-tk7vn1v1	329	18	viral	viral	JJ
cord-278081-tk7vn1v1	329	19	insertion	insertion	NN
cord-278081-tk7vn1v1	329	20	.	.	.
cord-278081-tk7vn1v1	330	1	The	the	DT
cord-278081-tk7vn1v1	330	2	particulars	particular	NNS
cord-278081-tk7vn1v1	330	3	of	of	IN
cord-278081-tk7vn1v1	330	4	the	the	DT
cord-278081-tk7vn1v1	330	5	fragile	fragile	JJ
cord-278081-tk7vn1v1	330	6	site	site	NN
cord-278081-tk7vn1v1	330	7	and	and	CC
cord-278081-tk7vn1v1	330	8	its	-PRON-	PRP$
cord-278081-tk7vn1v1	330	9	vulnerability	vulnerability	NN
cord-278081-tk7vn1v1	330	10	to	to	IN
cord-278081-tk7vn1v1	330	11	viral	viral	JJ
cord-278081-tk7vn1v1	330	12	insertion	insertion	NN
cord-278081-tk7vn1v1	330	13	may	may	MD
cord-278081-tk7vn1v1	330	14	add	add	VB
cord-278081-tk7vn1v1	330	15	to	to	IN
cord-278081-tk7vn1v1	330	16	the	the	DT
cord-278081-tk7vn1v1	330	17	genetic	genetic	JJ
cord-278081-tk7vn1v1	330	18	susceptibility	susceptibility	NN
cord-278081-tk7vn1v1	330	19	of	of	IN
cord-278081-tk7vn1v1	330	20	an	an	DT
cord-278081-tk7vn1v1	330	21	individual	individual	NN
cord-278081-tk7vn1v1	330	22	.	.	.
cord-278081-tk7vn1v1	331	1	The	the	DT
cord-278081-tk7vn1v1	331	2	previous	previous	JJ
cord-278081-tk7vn1v1	331	3	version	version	NN
cord-278081-tk7vn1v1	331	4	of	of	IN
cord-278081-tk7vn1v1	331	5	the	the	DT
cord-278081-tk7vn1v1	331	6	"	"	``
cord-278081-tk7vn1v1	331	7	X	x	NN
cord-278081-tk7vn1v1	331	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	331	9	-	-	HYPH
cord-278081-tk7vn1v1	331	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	331	11	nexus	nexus	NN
cord-278081-tk7vn1v1	331	12	"	"	''
cord-278081-tk7vn1v1	331	13	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	331	14	,	,	,
cord-278081-tk7vn1v1	331	15	or	or	CC
cord-278081-tk7vn1v1	331	16	simply	simply	RB
cord-278081-tk7vn1v1	331	17	the	the	DT
cord-278081-tk7vn1v1	331	18	"	"	``
cord-278081-tk7vn1v1	331	19	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	331	20	"	"	''
cord-278081-tk7vn1v1	331	21	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	331	22	,	,	,
cord-278081-tk7vn1v1	331	23	explained	explain	VBD
cord-278081-tk7vn1v1	331	24	how	how	WRB
cord-278081-tk7vn1v1	331	25	an	an	DT
cord-278081-tk7vn1v1	331	26	overly	overly	RB
cord-278081-tk7vn1v1	331	27	stressed	stressed	JJ
cord-278081-tk7vn1v1	331	28	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	331	29	could	could	MD
cord-278081-tk7vn1v1	331	30	disrupt	disrupt	VB
cord-278081-tk7vn1v1	331	31	neighboring	neighboring	NN
cord-278081-tk7vn1v1	331	32	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	331	33	,	,	,
cord-278081-tk7vn1v1	331	34	especially	especially	RB
cord-278081-tk7vn1v1	331	35	the	the	DT
cord-278081-tk7vn1v1	331	36	Barr	Barr	NNP
cord-278081-tk7vn1v1	331	37	body	body	NN
cord-278081-tk7vn1v1	331	38	.	.	.
cord-278081-tk7vn1v1	332	1	As	as	IN
cord-278081-tk7vn1v1	332	2	a	a	DT
cord-278081-tk7vn1v1	332	3	result	result	NN
cord-278081-tk7vn1v1	332	4	,	,	,
cord-278081-tk7vn1v1	332	5	there	there	EX
cord-278081-tk7vn1v1	332	6	could	could	MD
cord-278081-tk7vn1v1	332	7	be	be	VB
cord-278081-tk7vn1v1	332	8	detrimental	detrimental	JJ
cord-278081-tk7vn1v1	332	9	increases	increase	NNS
cord-278081-tk7vn1v1	332	10	in	in	IN
cord-278081-tk7vn1v1	332	11	synthesis	synthesis	NN
cord-278081-tk7vn1v1	332	12	and	and	CC
cord-278081-tk7vn1v1	332	13	recycling	recycling	NN
cord-278081-tk7vn1v1	332	14	of	of	IN
cord-278081-tk7vn1v1	332	15	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	332	16	that	that	WDT
cord-278081-tk7vn1v1	332	17	could	could	MD
cord-278081-tk7vn1v1	332	18	impact	impact	VB
cord-278081-tk7vn1v1	332	19	cellular	cellular	JJ
cord-278081-tk7vn1v1	332	20	methylation	methylation	NN
cord-278081-tk7vn1v1	332	21	and	and	CC
cord-278081-tk7vn1v1	332	22	potentially	potentially	RB
cord-278081-tk7vn1v1	332	23	stabilize	stabilize	VB
cord-278081-tk7vn1v1	332	24	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	332	25	complexes	complex	NNS
cord-278081-tk7vn1v1	332	26	of	of	IN
cord-278081-tk7vn1v1	332	27	nucleolar	nucleolar	NNP
cord-278081-tk7vn1v1	332	28	and	and	CC
cord-278081-tk7vn1v1	332	29	chromatin	chromatin	NN
cord-278081-tk7vn1v1	332	30	components	component	NNS
cord-278081-tk7vn1v1	332	31	.	.	.
cord-278081-tk7vn1v1	333	1	The	the	DT
cord-278081-tk7vn1v1	333	2	point	point	NN
cord-278081-tk7vn1v1	333	3	was	be	VBD
cord-278081-tk7vn1v1	333	4	made	make	VBN
cord-278081-tk7vn1v1	333	5	that	that	IN
cord-278081-tk7vn1v1	333	6	many	many	JJ
cord-278081-tk7vn1v1	333	7	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	333	8	in	in	IN
cord-278081-tk7vn1v1	333	9	SLE	SLE	NNP
cord-278081-tk7vn1v1	333	10	are	be	VBP
cord-278081-tk7vn1v1	333	11	,	,	,
cord-278081-tk7vn1v1	333	12	at	at	IN
cord-278081-tk7vn1v1	333	13	least	least	JJS
cord-278081-tk7vn1v1	333	14	transiently	transiently	RB
cord-278081-tk7vn1v1	333	15	,	,	,
cord-278081-tk7vn1v1	333	16	components	component	NNS
cord-278081-tk7vn1v1	333	17	of	of	IN
cord-278081-tk7vn1v1	333	18	the	the	DT
cord-278081-tk7vn1v1	333	19	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	333	20	but	but	CC
cord-278081-tk7vn1v1	333	21	the	the	DT
cord-278081-tk7vn1v1	333	22	means	mean	NNS
cord-278081-tk7vn1v1	333	23	by	by	IN
cord-278081-tk7vn1v1	333	24	which	which	WDT
cord-278081-tk7vn1v1	333	25	such	such	JJ
cord-278081-tk7vn1v1	333	26	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	333	27	components	component	NNS
cord-278081-tk7vn1v1	333	28	could	could	MD
cord-278081-tk7vn1v1	333	29	become	become	VB
cord-278081-tk7vn1v1	333	30	autoantigenic	autoantigenic	NNP
cord-278081-tk7vn1v1	333	31	was	be	VBD
cord-278081-tk7vn1v1	333	32	not	not	RB
cord-278081-tk7vn1v1	333	33	presented	present	VBN
cord-278081-tk7vn1v1	333	34	.	.	.
cord-278081-tk7vn1v1	334	1	Now	now	RB
cord-278081-tk7vn1v1	334	2	,	,	,
cord-278081-tk7vn1v1	334	3	with	with	IN
cord-278081-tk7vn1v1	334	4	this	this	DT
cord-278081-tk7vn1v1	334	5	work	work	NN
cord-278081-tk7vn1v1	334	6	,	,	,
cord-278081-tk7vn1v1	334	7	the	the	DT
cord-278081-tk7vn1v1	334	8	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	334	9	has	have	VBZ
cord-278081-tk7vn1v1	334	10	been	be	VBN
cord-278081-tk7vn1v1	334	11	extended	extend	VBN
cord-278081-tk7vn1v1	334	12	to	to	TO
cord-278081-tk7vn1v1	334	13	include	include	VB
cord-278081-tk7vn1v1	334	14	disruption	disruption	NN
cord-278081-tk7vn1v1	334	15	of	of	IN
cord-278081-tk7vn1v1	334	16	the	the	DT
cord-278081-tk7vn1v1	334	17	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	334	18	as	as	IN
cord-278081-tk7vn1v1	334	19	an	an	DT
cord-278081-tk7vn1v1	334	20	additional	additional	JJ
cord-278081-tk7vn1v1	334	21	step	step	NN
cord-278081-tk7vn1v1	334	22	.	.	.
cord-278081-tk7vn1v1	335	1	A	a	DT
cord-278081-tk7vn1v1	335	2	disrupted	disrupt	VBN
cord-278081-tk7vn1v1	335	3	Barr	Barr	NNP
cord-278081-tk7vn1v1	335	4	body	body	NN
cord-278081-tk7vn1v1	335	5	could	could	MD
cord-278081-tk7vn1v1	335	6	generate	generate	VB
cord-278081-tk7vn1v1	335	7	an	an	DT
cord-278081-tk7vn1v1	335	8	abundance	abundance	NN
cord-278081-tk7vn1v1	335	9	of	of	IN
cord-278081-tk7vn1v1	335	10	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	335	11	and	and	CC
cord-278081-tk7vn1v1	335	12	Alu	Alu	NNP
cord-278081-tk7vn1v1	335	13	RNA	RNA	NNP
cord-278081-tk7vn1v1	335	14	from	from	IN
cord-278081-tk7vn1v1	335	15	X	x	NN
cord-278081-tk7vn1v1	335	16	-	-	HYPH
cord-278081-tk7vn1v1	335	17	linked	link	VBN
cord-278081-tk7vn1v1	335	18	genes	gene	NNS
cord-278081-tk7vn1v1	335	19	and	and	CC
cord-278081-tk7vn1v1	335	20	elements	element	NNS
cord-278081-tk7vn1v1	335	21	that	that	WDT
cord-278081-tk7vn1v1	335	22	further	further	JJ
cord-278081-tk7vn1v1	335	23	stress	stress	NN
cord-278081-tk7vn1v1	335	24	and	and	CC
cord-278081-tk7vn1v1	335	25	damage	damage	VB
cord-278081-tk7vn1v1	335	26	the	the	DT
cord-278081-tk7vn1v1	335	27	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	335	28	,	,	,
cord-278081-tk7vn1v1	335	29	making	make	VBG
cord-278081-tk7vn1v1	335	30	it	-PRON-	PRP
cord-278081-tk7vn1v1	335	31	very	very	RB
cord-278081-tk7vn1v1	335	32	inefficient	inefficient	JJ
cord-278081-tk7vn1v1	335	33	in	in	IN
cord-278081-tk7vn1v1	335	34	its	-PRON-	PRP$
cord-278081-tk7vn1v1	335	35	functions	function	NNS
cord-278081-tk7vn1v1	335	36	,	,	,
cord-278081-tk7vn1v1	335	37	even	even	RB
cord-278081-tk7vn1v1	335	38	fragmenting	fragment	VBG
cord-278081-tk7vn1v1	335	39	it	-PRON-	PRP
cord-278081-tk7vn1v1	335	40	and	and	CC
cord-278081-tk7vn1v1	335	41	possibly	possibly	RB
cord-278081-tk7vn1v1	335	42	leading	lead	VBG
cord-278081-tk7vn1v1	335	43	to	to	IN
cord-278081-tk7vn1v1	335	44	cell	cell	NN
cord-278081-tk7vn1v1	335	45	death	death	NN
cord-278081-tk7vn1v1	335	46	.	.	.
cord-278081-tk7vn1v1	336	1	And	and	CC
cord-278081-tk7vn1v1	336	2	there	there	EX
cord-278081-tk7vn1v1	336	3	may	may	MD
cord-278081-tk7vn1v1	336	4	be	be	VB
cord-278081-tk7vn1v1	336	5	overexpression	overexpression	NN
cord-278081-tk7vn1v1	336	6	of	of	IN
cord-278081-tk7vn1v1	336	7	SAT1	SAT1	NNP
cord-278081-tk7vn1v1	336	8	that	that	WDT
cord-278081-tk7vn1v1	336	9	hampers	hamper	VBZ
cord-278081-tk7vn1v1	336	10	the	the	DT
cord-278081-tk7vn1v1	336	11	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	336	12	in	in	IN
cord-278081-tk7vn1v1	336	13	subsequent	subsequent	JJ
cord-278081-tk7vn1v1	336	14	stress	stress	NN
cord-278081-tk7vn1v1	336	15	events	event	NNS
cord-278081-tk7vn1v1	336	16	since	since	IN
cord-278081-tk7vn1v1	336	17	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	336	18	may	may	MD
cord-278081-tk7vn1v1	336	19	be	be	VB
cord-278081-tk7vn1v1	336	20	converted	convert	VBN
cord-278081-tk7vn1v1	336	21	to	to	IN
cord-278081-tk7vn1v1	336	22	a	a	DT
cord-278081-tk7vn1v1	336	23	predominance	predominance	NN
cord-278081-tk7vn1v1	336	24	of	of	IN
cord-278081-tk7vn1v1	336	25	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	336	26	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	336	27	that	that	WDT
cord-278081-tk7vn1v1	336	28	are	be	VBP
cord-278081-tk7vn1v1	336	29	less	less	RBR
cord-278081-tk7vn1v1	336	30	effective	effective	JJ
cord-278081-tk7vn1v1	336	31	at	at	IN
cord-278081-tk7vn1v1	336	32	or	or	CC
cord-278081-tk7vn1v1	336	33	even	even	RB
cord-278081-tk7vn1v1	336	34	detrimental	detrimental	JJ
cord-278081-tk7vn1v1	336	35	to	to	IN
cord-278081-tk7vn1v1	336	36	proper	proper	JJ
cord-278081-tk7vn1v1	336	37	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	336	38	folding	folding	NN
cord-278081-tk7vn1v1	336	39	and	and	CC
cord-278081-tk7vn1v1	336	40	assembly	assembly	NN
cord-278081-tk7vn1v1	336	41	of	of	IN
cord-278081-tk7vn1v1	336	42	RNAs	RNAs	NNPS
cord-278081-tk7vn1v1	336	43	and	and	CC
cord-278081-tk7vn1v1	336	44	RNPs	rnp	NNS
cord-278081-tk7vn1v1	336	45	.	.	.
cord-278081-tk7vn1v1	337	1	Meanwhile	meanwhile	RB
cord-278081-tk7vn1v1	337	2	during	during	IN
cord-278081-tk7vn1v1	337	3	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	337	4	disruption	disruption	NN
cord-278081-tk7vn1v1	337	5	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	337	6	may	may	MD
cord-278081-tk7vn1v1	337	7	be	be	VB
cord-278081-tk7vn1v1	337	8	created	create	VBN
cord-278081-tk7vn1v1	337	9	,	,	,
cord-278081-tk7vn1v1	337	10	stabilized	stabilize	VBN
cord-278081-tk7vn1v1	337	11	and	and	CC
cord-278081-tk7vn1v1	337	12	released	release	VBN
cord-278081-tk7vn1v1	337	13	extracellularly	extracellularly	RB
cord-278081-tk7vn1v1	337	14	.	.	.
cord-278081-tk7vn1v1	338	1	Further	further	JJ
cord-278081-tk7vn1v1	338	2	work	work	NN
cord-278081-tk7vn1v1	338	3	is	be	VBZ
cord-278081-tk7vn1v1	338	4	needed	need	VBN
cord-278081-tk7vn1v1	338	5	to	to	TO
cord-278081-tk7vn1v1	338	6	understand	understand	VB
cord-278081-tk7vn1v1	338	7	how	how	WRB
cord-278081-tk7vn1v1	338	8	the	the	DT
cord-278081-tk7vn1v1	338	9	various	various	JJ
cord-278081-tk7vn1v1	338	10	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	338	11	provoke	provoke	VBP
cord-278081-tk7vn1v1	338	12	the	the	DT
cord-278081-tk7vn1v1	338	13	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	338	14	response	response	NN
cord-278081-tk7vn1v1	338	15	.	.	.
cord-278081-tk7vn1v1	339	1	Is	be	VBZ
cord-278081-tk7vn1v1	339	2	it	-PRON-	PRP
cord-278081-tk7vn1v1	339	3	,	,	,
cord-278081-tk7vn1v1	339	4	for	for	IN
cord-278081-tk7vn1v1	339	5	example	example	NN
cord-278081-tk7vn1v1	339	6	,	,	,
cord-278081-tk7vn1v1	339	7	a	a	DT
cord-278081-tk7vn1v1	339	8	conformational	conformational	JJ
cord-278081-tk7vn1v1	339	9	alteration	alteration	NN
cord-278081-tk7vn1v1	339	10	of	of	IN
cord-278081-tk7vn1v1	339	11	the	the	DT
cord-278081-tk7vn1v1	339	12	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	339	13	subunits	subunit	NNS
cord-278081-tk7vn1v1	339	14	stabilized	stabilize	VBN
cord-278081-tk7vn1v1	339	15	by	by	IN
cord-278081-tk7vn1v1	339	16	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	339	17	,	,	,
cord-278081-tk7vn1v1	339	18	or	or	CC
cord-278081-tk7vn1v1	339	19	incomplete	incomplete	JJ
cord-278081-tk7vn1v1	339	20	assembly	assembly	NN
cord-278081-tk7vn1v1	339	21	of	of	IN
cord-278081-tk7vn1v1	339	22	an	an	DT
cord-278081-tk7vn1v1	339	23	RNP	RNP	NNP
cord-278081-tk7vn1v1	339	24	?	?	.
cord-278081-tk7vn1v1	340	1	Or	or	CC
cord-278081-tk7vn1v1	340	2	could	could	MD
cord-278081-tk7vn1v1	340	3	it	-PRON-	PRP
cord-278081-tk7vn1v1	340	4	be	be	VB
cord-278081-tk7vn1v1	340	5	"	"	``
cord-278081-tk7vn1v1	340	6	guilt	guilt	NN
cord-278081-tk7vn1v1	340	7	by	by	IN
cord-278081-tk7vn1v1	340	8	association	association	NN
cord-278081-tk7vn1v1	340	9	"	"	''
cord-278081-tk7vn1v1	340	10	such	such	JJ
cord-278081-tk7vn1v1	340	11	as	as	IN
cord-278081-tk7vn1v1	341	1	SSA	SSA	NNP
cord-278081-tk7vn1v1	341	2	/	/	SYM
cord-278081-tk7vn1v1	341	3	Ro	Ro	NNP
cord-278081-tk7vn1v1	341	4	bound	bind	VBN
cord-278081-tk7vn1v1	341	5	to	to	IN
cord-278081-tk7vn1v1	341	6	misfolded	misfolde	VBN
cord-278081-tk7vn1v1	341	7	RNAs	rna	NNS
cord-278081-tk7vn1v1	341	8	stabilized	stabilize	VBD
cord-278081-tk7vn1v1	341	9	with	with	IN
cord-278081-tk7vn1v1	341	10	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	341	11	that	that	WDT
cord-278081-tk7vn1v1	341	12	prevent	prevent	VBP
cord-278081-tk7vn1v1	341	13	proper	proper	JJ
cord-278081-tk7vn1v1	341	14	refolding	refolding	NN
cord-278081-tk7vn1v1	341	15	?	?	.
cord-278081-tk7vn1v1	342	1	There	there	EX
cord-278081-tk7vn1v1	342	2	may	may	MD
cord-278081-tk7vn1v1	342	3	be	be	VB
cord-278081-tk7vn1v1	342	4	incorporation	incorporation	NN
cord-278081-tk7vn1v1	342	5	of	of	IN
cord-278081-tk7vn1v1	342	6	viral	viral	JJ
cord-278081-tk7vn1v1	342	7	components	component	NNS
cord-278081-tk7vn1v1	342	8	in	in	IN
cord-278081-tk7vn1v1	342	9	the	the	DT
cord-278081-tk7vn1v1	342	10	RNPs	rnp	NNS
cord-278081-tk7vn1v1	342	11	that	that	WDT
cord-278081-tk7vn1v1	342	12	make	make	VBP
cord-278081-tk7vn1v1	342	13	it	-PRON-	PRP
cord-278081-tk7vn1v1	342	14	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	342	15	.	.	.
cord-278081-tk7vn1v1	343	1	Or	or	CC
cord-278081-tk7vn1v1	343	2	could	could	MD
cord-278081-tk7vn1v1	343	3	it	-PRON-	PRP
cord-278081-tk7vn1v1	343	4	be	be	VB
cord-278081-tk7vn1v1	343	5	abnormal	abnormal	JJ
cord-278081-tk7vn1v1	343	6	localization	localization	NN
cord-278081-tk7vn1v1	343	7	and/or	and/or	CC
cord-278081-tk7vn1v1	343	8	modification	modification	NN
cord-278081-tk7vn1v1	343	9	of	of	IN
cord-278081-tk7vn1v1	343	10	proteins	protein	NNS
cord-278081-tk7vn1v1	343	11	that	that	WDT
cord-278081-tk7vn1v1	343	12	are	be	VBP
cord-278081-tk7vn1v1	343	13	misdirected	misdirect	VBN
cord-278081-tk7vn1v1	343	14	due	due	IN
cord-278081-tk7vn1v1	343	15	to	to	IN
cord-278081-tk7vn1v1	343	16	Alu	Alu	NNP
cord-278081-tk7vn1v1	343	17	RNA	RNA	NNP
cord-278081-tk7vn1v1	343	18	interference	interference	NN
cord-278081-tk7vn1v1	343	19	with	with	IN
cord-278081-tk7vn1v1	343	20	SRP	SRP	NNP
cord-278081-tk7vn1v1	343	21	assembly	assembly	NN
cord-278081-tk7vn1v1	343	22	(	(	-LRB-
cord-278081-tk7vn1v1	343	23	72	72	CD
cord-278081-tk7vn1v1	343	24	)	)	-RRB-
cord-278081-tk7vn1v1	343	25	.	.	.
cord-278081-tk7vn1v1	344	1	Epitope	epitope	NN
cord-278081-tk7vn1v1	344	2	spreading	spread	VBG
cord-278081-tk7vn1v1	344	3	from	from	IN
cord-278081-tk7vn1v1	344	4	the	the	DT
cord-278081-tk7vn1v1	344	5	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	344	6	complex	complex	JJ
cord-278081-tk7vn1v1	344	7	to	to	IN
cord-278081-tk7vn1v1	344	8	the	the	DT
cord-278081-tk7vn1v1	344	9	normal	normal	JJ
cord-278081-tk7vn1v1	344	10	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	344	11	protein	protein	NN
cord-278081-tk7vn1v1	344	12	would	would	MD
cord-278081-tk7vn1v1	344	13	seem	seem	VB
cord-278081-tk7vn1v1	344	14	to	to	TO
cord-278081-tk7vn1v1	344	15	have	have	VB
cord-278081-tk7vn1v1	344	16	a	a	DT
cord-278081-tk7vn1v1	344	17	role	role	NN
cord-278081-tk7vn1v1	344	18	in	in	IN
cord-278081-tk7vn1v1	344	19	the	the	DT
cord-278081-tk7vn1v1	344	20	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	344	21	response	response	NN
cord-278081-tk7vn1v1	344	22	with	with	IN
cord-278081-tk7vn1v1	344	23	the	the	DT
cord-278081-tk7vn1v1	344	24	greater	great	JJR
cord-278081-tk7vn1v1	344	25	abundance	abundance	NN
cord-278081-tk7vn1v1	344	26	of	of	IN
cord-278081-tk7vn1v1	344	27	the	the	DT
cord-278081-tk7vn1v1	344	28	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	344	29	protein	protein	NN
cord-278081-tk7vn1v1	344	30	then	then	RB
cord-278081-tk7vn1v1	344	31	providing	provide	VBG
cord-278081-tk7vn1v1	344	32	more	more	JJR
cord-278081-tk7vn1v1	344	33	of	of	IN
cord-278081-tk7vn1v1	344	34	the	the	DT
cord-278081-tk7vn1v1	344	35	provocation	provocation	NN
cord-278081-tk7vn1v1	344	36	than	than	IN
cord-278081-tk7vn1v1	344	37	the	the	DT
cord-278081-tk7vn1v1	344	38	original	original	JJ
cord-278081-tk7vn1v1	344	39	autoantigenic	autoantigenic	JJ
cord-278081-tk7vn1v1	344	40	complex	complex	NN
cord-278081-tk7vn1v1	344	41	.	.	.
cord-278081-tk7vn1v1	345	1	And	and	CC
cord-278081-tk7vn1v1	345	2	the	the	DT
cord-278081-tk7vn1v1	345	3	fragmentation	fragmentation	NN
cord-278081-tk7vn1v1	345	4	of	of	IN
cord-278081-tk7vn1v1	345	5	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	345	6	,	,	,
cord-278081-tk7vn1v1	345	7	as	as	IN
cord-278081-tk7vn1v1	345	8	described	describe	VBN
cord-278081-tk7vn1v1	345	9	here	here	RB
cord-278081-tk7vn1v1	345	10	,	,	,
cord-278081-tk7vn1v1	345	11	could	could	MD
cord-278081-tk7vn1v1	345	12	lead	lead	VB
cord-278081-tk7vn1v1	345	13	to	to	IN
cord-278081-tk7vn1v1	345	14	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	345	15	signaling	signaling	NN
cord-278081-tk7vn1v1	345	16	and	and	CC
cord-278081-tk7vn1v1	345	17	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	345	18	exposure	exposure	NN
cord-278081-tk7vn1v1	345	19	of	of	IN
cord-278081-tk7vn1v1	345	20	autoantigens	autoantigens	NNP
cord-278081-tk7vn1v1	345	21	.	.	.
cord-278081-tk7vn1v1	346	1	Testing	testing	NN
cord-278081-tk7vn1v1	346	2	of	of	IN
cord-278081-tk7vn1v1	346	3	the	the	DT
cord-278081-tk7vn1v1	346	4	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	346	5	can	can	MD
cord-278081-tk7vn1v1	346	6	use	use	VB
cord-278081-tk7vn1v1	346	7	powerful	powerful	JJ
cord-278081-tk7vn1v1	346	8	approaches	approach	NNS
cord-278081-tk7vn1v1	346	9	,	,	,
cord-278081-tk7vn1v1	346	10	such	such	JJ
cord-278081-tk7vn1v1	346	11	as	as	IN
cord-278081-tk7vn1v1	346	12	computational	computational	JJ
cord-278081-tk7vn1v1	346	13	molecular	molecular	JJ
cord-278081-tk7vn1v1	346	14	dynamics	dynamic	NNS
cord-278081-tk7vn1v1	346	15	and	and	CC
cord-278081-tk7vn1v1	346	16	single	single	JJ
cord-278081-tk7vn1v1	346	17	cell	cell	NN
cord-278081-tk7vn1v1	346	18	analysis	analysis	NN
cord-278081-tk7vn1v1	346	19	,	,	,
cord-278081-tk7vn1v1	346	20	that	that	WDT
cord-278081-tk7vn1v1	346	21	have	have	VBP
cord-278081-tk7vn1v1	346	22	now	now	RB
cord-278081-tk7vn1v1	346	23	reached	reach	VBN
cord-278081-tk7vn1v1	346	24	sophistication	sophistication	NN
cord-278081-tk7vn1v1	346	25	that	that	WDT
cord-278081-tk7vn1v1	346	26	allow	allow	VBP
cord-278081-tk7vn1v1	346	27	us	-PRON-	PRP
cord-278081-tk7vn1v1	346	28	to	to	TO
cord-278081-tk7vn1v1	346	29	explore	explore	VB
cord-278081-tk7vn1v1	346	30	the	the	DT
cord-278081-tk7vn1v1	346	31	interactions	interaction	NNS
cord-278081-tk7vn1v1	346	32	of	of	IN
cord-278081-tk7vn1v1	346	33	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	346	34	components	component	NNS
cord-278081-tk7vn1v1	346	35	as	as	IN
cord-278081-tk7vn1v1	346	36	they	-PRON-	PRP
cord-278081-tk7vn1v1	346	37	are	be	VBP
cord-278081-tk7vn1v1	346	38	normally	normally	RB
cord-278081-tk7vn1v1	346	39	processed	process	VBN
cord-278081-tk7vn1v1	346	40	and	and	CC
cord-278081-tk7vn1v1	346	41	the	the	DT
cord-278081-tk7vn1v1	346	42	possibilities	possibility	NNS
cord-278081-tk7vn1v1	346	43	of	of	IN
cord-278081-tk7vn1v1	346	44	how	how	WRB
cord-278081-tk7vn1v1	346	45	abnormalities	abnormality	NNS
cord-278081-tk7vn1v1	346	46	could	could	MD
cord-278081-tk7vn1v1	346	47	occur	occur	VB
cord-278081-tk7vn1v1	346	48	.	.	.
cord-278081-tk7vn1v1	347	1	For	for	IN
cord-278081-tk7vn1v1	347	2	example	example	NN
cord-278081-tk7vn1v1	347	3	,	,	,
cord-278081-tk7vn1v1	347	4	what	what	WP
cord-278081-tk7vn1v1	347	5	is	be	VBZ
cord-278081-tk7vn1v1	347	6	the	the	DT
cord-278081-tk7vn1v1	347	7	effect	effect	NN
cord-278081-tk7vn1v1	347	8	of	of	IN
cord-278081-tk7vn1v1	347	9	acetylated	acetylated	JJ
cord-278081-tk7vn1v1	347	10	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	347	11	if	if	IN
cord-278081-tk7vn1v1	347	12	they	-PRON-	PRP
cord-278081-tk7vn1v1	347	13	were	be	VBD
cord-278081-tk7vn1v1	347	14	to	to	TO
cord-278081-tk7vn1v1	347	15	compete	compete	VB
cord-278081-tk7vn1v1	347	16	with	with	IN
cord-278081-tk7vn1v1	347	17	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	347	18	and	and	CC
cord-278081-tk7vn1v1	347	19	spermine	spermine	NN
cord-278081-tk7vn1v1	347	20	in	in	IN
cord-278081-tk7vn1v1	347	21	the	the	DT
cord-278081-tk7vn1v1	347	22	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	347	23	folding	folding	NN
cord-278081-tk7vn1v1	347	24	and	and	CC
cord-278081-tk7vn1v1	347	25	assembly	assembly	NN
cord-278081-tk7vn1v1	347	26	of	of	IN
cord-278081-tk7vn1v1	347	27	RNPs	rnp	NNS
cord-278081-tk7vn1v1	347	28	?	?	.
cord-278081-tk7vn1v1	348	1	What	what	WP
cord-278081-tk7vn1v1	348	2	are	be	VBP
cord-278081-tk7vn1v1	348	3	the	the	DT
cord-278081-tk7vn1v1	348	4	interactions	interaction	NNS
cord-278081-tk7vn1v1	348	5	and	and	CC
cord-278081-tk7vn1v1	348	6	resulting	result	VBG
cord-278081-tk7vn1v1	348	7	structures	structure	NNS
cord-278081-tk7vn1v1	348	8	of	of	IN
cord-278081-tk7vn1v1	348	9	intronic	intronic	NNP
cord-278081-tk7vn1v1	348	10	Alu	Alu	NNP
cord-278081-tk7vn1v1	348	11	RNA	RNA	NNP
cord-278081-tk7vn1v1	348	12	with	with	IN
cord-278081-tk7vn1v1	348	13	nucleolin	nucleolin	NNP
cord-278081-tk7vn1v1	348	14	?	?	.
cord-278081-tk7vn1v1	349	1	And	and	CC
cord-278081-tk7vn1v1	349	2	what	what	WP
cord-278081-tk7vn1v1	349	3	is	be	VBZ
cord-278081-tk7vn1v1	349	4	the	the	DT
cord-278081-tk7vn1v1	349	5	distribution	distribution	NN
cord-278081-tk7vn1v1	349	6	and	and	CC
cord-278081-tk7vn1v1	349	7	composition	composition	NN
cord-278081-tk7vn1v1	349	8	of	of	IN
cord-278081-tk7vn1v1	349	9	RNAs	rna	NNS
cord-278081-tk7vn1v1	349	10	and	and	CC
cord-278081-tk7vn1v1	349	11	proteins	protein	NNS
cord-278081-tk7vn1v1	349	12	in	in	IN
cord-278081-tk7vn1v1	349	13	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	349	14	fragments	fragment	NNS
cord-278081-tk7vn1v1	349	15	compared	compare	VBN
cord-278081-tk7vn1v1	349	16	to	to	IN
cord-278081-tk7vn1v1	349	17	intact	intact	JJ
cord-278081-tk7vn1v1	349	18	nucleoli	nucleoli	JJ
cord-278081-tk7vn1v1	349	19	?	?	.
cord-278081-tk7vn1v1	350	1	And	and	CC
cord-278081-tk7vn1v1	350	2	,	,	,
cord-278081-tk7vn1v1	350	3	perhaps	perhaps	RB
cord-278081-tk7vn1v1	350	4	most	most	RBS
cord-278081-tk7vn1v1	350	5	important	important	JJ
cord-278081-tk7vn1v1	350	6	,	,	,
cord-278081-tk7vn1v1	350	7	what	what	WP
cord-278081-tk7vn1v1	350	8	does	do	VBZ
cord-278081-tk7vn1v1	350	9	this	this	DT
cord-278081-tk7vn1v1	350	10	new	new	JJ
cord-278081-tk7vn1v1	350	11	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	350	12	present	present	JJ
cord-278081-tk7vn1v1	350	13	as	as	RB
cord-278081-tk7vn1v1	350	14	far	far	RB
cord-278081-tk7vn1v1	350	15	as	as	IN
cord-278081-tk7vn1v1	350	16	therapeutic	therapeutic	JJ
cord-278081-tk7vn1v1	350	17	targets	target	NNS
cord-278081-tk7vn1v1	350	18	?	?	.
cord-278081-tk7vn1v1	351	1	Certainly	certainly	RB
cord-278081-tk7vn1v1	351	2	suppressing	suppress	VBG
cord-278081-tk7vn1v1	351	3	viral	viral	JJ
cord-278081-tk7vn1v1	351	4	activity	activity	NN
cord-278081-tk7vn1v1	351	5	,	,	,
cord-278081-tk7vn1v1	351	6	MYC	MYC	NNP
cord-278081-tk7vn1v1	351	7	activity	activity	NN
cord-278081-tk7vn1v1	351	8	,	,	,
cord-278081-tk7vn1v1	351	9	polyamine	polyamine	NN
cord-278081-tk7vn1v1	351	10	synthesis	synthesis	NN
cord-278081-tk7vn1v1	351	11	,	,	,
cord-278081-tk7vn1v1	351	12	and	and	CC
cord-278081-tk7vn1v1	351	13	polyamine	polyamine	NN
cord-278081-tk7vn1v1	351	14	recycling	recycling	NN
cord-278081-tk7vn1v1	351	15	are	be	VBP
cord-278081-tk7vn1v1	351	16	important	important	JJ
cord-278081-tk7vn1v1	351	17	targets	target	NNS
cord-278081-tk7vn1v1	351	18	but	but	CC
cord-278081-tk7vn1v1	351	19	also	also	RB
cord-278081-tk7vn1v1	351	20	newer	new	JJR
cord-278081-tk7vn1v1	351	21	areas	area	NNS
cord-278081-tk7vn1v1	351	22	,	,	,
cord-278081-tk7vn1v1	351	23	such	such	JJ
cord-278081-tk7vn1v1	351	24	as	as	IN
cord-278081-tk7vn1v1	351	25	the	the	DT
cord-278081-tk7vn1v1	351	26	cGAS	cgas	JJ
cord-278081-tk7vn1v1	351	27	-	-	HYPH
cord-278081-tk7vn1v1	351	28	STING	sting	NN
cord-278081-tk7vn1v1	351	29	pathway	pathway	NN
cord-278081-tk7vn1v1	351	30	are	be	VBP
cord-278081-tk7vn1v1	351	31	promising	promising	JJ
cord-278081-tk7vn1v1	351	32	targets	target	NNS
cord-278081-tk7vn1v1	351	33	too	too	RB
cord-278081-tk7vn1v1	351	34	.	.	.
cord-278081-tk7vn1v1	352	1	The	the	DT
cord-278081-tk7vn1v1	352	2	importance	importance	NN
cord-278081-tk7vn1v1	352	3	of	of	IN
cord-278081-tk7vn1v1	352	4	Alu	Alu	NNP
cord-278081-tk7vn1v1	352	5	elements	element	NNS
cord-278081-tk7vn1v1	352	6	implied	imply	VBN
cord-278081-tk7vn1v1	352	7	by	by	IN
cord-278081-tk7vn1v1	352	8	this	this	DT
cord-278081-tk7vn1v1	352	9	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	352	10	calls	call	VBZ
cord-278081-tk7vn1v1	352	11	into	into	IN
cord-278081-tk7vn1v1	352	12	question	question	NN
cord-278081-tk7vn1v1	352	13	the	the	DT
cord-278081-tk7vn1v1	352	14	use	use	NN
cord-278081-tk7vn1v1	352	15	of	of	IN
cord-278081-tk7vn1v1	352	16	mouse	mouse	NN
cord-278081-tk7vn1v1	352	17	models	model	NNS
cord-278081-tk7vn1v1	352	18	of	of	IN
cord-278081-tk7vn1v1	352	19	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	352	20	diseases	disease	NNS
cord-278081-tk7vn1v1	352	21	since	since	IN
cord-278081-tk7vn1v1	352	22	mice	mouse	NNS
cord-278081-tk7vn1v1	352	23	do	do	VBP
cord-278081-tk7vn1v1	352	24	not	not	RB
cord-278081-tk7vn1v1	352	25	have	have	VB
cord-278081-tk7vn1v1	352	26	the	the	DT
cord-278081-tk7vn1v1	352	27	extensive	extensive	JJ
cord-278081-tk7vn1v1	352	28	amount	amount	NN
cord-278081-tk7vn1v1	352	29	of	of	IN
cord-278081-tk7vn1v1	352	30	Alu	Alu	NNP
cord-278081-tk7vn1v1	352	31	elements	element	NNS
cord-278081-tk7vn1v1	352	32	seen	see	VBN
cord-278081-tk7vn1v1	352	33	in	in	IN
cord-278081-tk7vn1v1	352	34	humans	human	NNS
cord-278081-tk7vn1v1	352	35	(	(	-LRB-
cord-278081-tk7vn1v1	352	36	certainly	certainly	RB
cord-278081-tk7vn1v1	352	37	not	not	RB
cord-278081-tk7vn1v1	352	38	a	a	DT
cord-278081-tk7vn1v1	352	39	cluster	cluster	NN
cord-278081-tk7vn1v1	352	40	of	of	IN
cord-278081-tk7vn1v1	352	41	28.8	28.8	CD
cord-278081-tk7vn1v1	352	42	%	%	NN
cord-278081-tk7vn1v1	352	43	seen	see	VBN
cord-278081-tk7vn1v1	352	44	in	in	IN
cord-278081-tk7vn1v1	352	45	the	the	DT
cord-278081-tk7vn1v1	352	46	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	352	47	of	of	IN
cord-278081-tk7vn1v1	352	48	the	the	DT
cord-278081-tk7vn1v1	352	49	human	human	JJ
cord-278081-tk7vn1v1	352	50	X	X	NNP
cord-278081-tk7vn1v1	352	51	)	)	-RRB-
cord-278081-tk7vn1v1	352	52	.	.	.
cord-278081-tk7vn1v1	353	1	In	in	IN
cord-278081-tk7vn1v1	353	2	addition	addition	NN
cord-278081-tk7vn1v1	353	3	,	,	,
cord-278081-tk7vn1v1	353	4	the	the	DT
cord-278081-tk7vn1v1	353	5	mouse	mouse	NN
cord-278081-tk7vn1v1	353	6	X	x	NN
cord-278081-tk7vn1v1	353	7	chromosome	chromosome	NN
cord-278081-tk7vn1v1	353	8	is	be	VBZ
cord-278081-tk7vn1v1	353	9	telocentric	telocentric	JJ
cord-278081-tk7vn1v1	353	10	(	(	-LRB-
cord-278081-tk7vn1v1	353	11	just	just	RB
cord-278081-tk7vn1v1	353	12	one	one	CD
cord-278081-tk7vn1v1	353	13	long	long	JJ
cord-278081-tk7vn1v1	353	14	arm	arm	NN
cord-278081-tk7vn1v1	353	15	)	)	-RRB-
cord-278081-tk7vn1v1	353	16	whereas	whereas	IN
cord-278081-tk7vn1v1	353	17	the	the	DT
cord-278081-tk7vn1v1	353	18	human	human	JJ
cord-278081-tk7vn1v1	353	19	X	x	NN
cord-278081-tk7vn1v1	353	20	is	be	VBZ
cord-278081-tk7vn1v1	353	21	submetacentric	submetacentric	NNP
cord-278081-tk7vn1v1	353	22	(	(	-LRB-
cord-278081-tk7vn1v1	353	23	a	a	DT
cord-278081-tk7vn1v1	353	24	long	long	JJ
cord-278081-tk7vn1v1	353	25	arm	arm	NN
cord-278081-tk7vn1v1	353	26	and	and	CC
cord-278081-tk7vn1v1	353	27	a	a	DT
cord-278081-tk7vn1v1	353	28	short	short	JJ
cord-278081-tk7vn1v1	353	29	arm	arm	NN
cord-278081-tk7vn1v1	353	30	)	)	-RRB-
cord-278081-tk7vn1v1	353	31	.	.	.
cord-278081-tk7vn1v1	354	1	The	the	DT
cord-278081-tk7vn1v1	354	2	mouse	mouse	NN
cord-278081-tk7vn1v1	354	3	X	x	NN
cord-278081-tk7vn1v1	354	4	inactivation	inactivation	NN
cord-278081-tk7vn1v1	354	5	would	would	MD
cord-278081-tk7vn1v1	354	6	be	be	VB
cord-278081-tk7vn1v1	354	7	relatively	relatively	RB
cord-278081-tk7vn1v1	354	8	consistent	consistent	JJ
cord-278081-tk7vn1v1	354	9	since	since	IN
cord-278081-tk7vn1v1	354	10	it	-PRON-	PRP
cord-278081-tk7vn1v1	354	11	does	do	VBZ
cord-278081-tk7vn1v1	354	12	not	not	RB
cord-278081-tk7vn1v1	354	13	negotiate	negotiate	VB
cord-278081-tk7vn1v1	354	14	a	a	DT
cord-278081-tk7vn1v1	354	15	centromere	centromere	NN
cord-278081-tk7vn1v1	354	16	.	.	.
cord-278081-tk7vn1v1	355	1	X	x	NN
cord-278081-tk7vn1v1	355	2	inactivation	inactivation	NN
cord-278081-tk7vn1v1	355	3	researchers	researcher	NNS
cord-278081-tk7vn1v1	355	4	complain	complain	VBP
cord-278081-tk7vn1v1	355	5	that	that	IN
cord-278081-tk7vn1v1	355	6	it	-PRON-	PRP
cord-278081-tk7vn1v1	355	7	is	be	VBZ
cord-278081-tk7vn1v1	355	8	difficult	difficult	JJ
cord-278081-tk7vn1v1	355	9	to	to	TO
cord-278081-tk7vn1v1	355	10	study	study	VB
cord-278081-tk7vn1v1	355	11	partial	partial	JJ
cord-278081-tk7vn1v1	355	12	X	x	NN
cord-278081-tk7vn1v1	355	13	reactivation	reactivation	NN
cord-278081-tk7vn1v1	355	14	in	in	IN
cord-278081-tk7vn1v1	355	15	mice	mouse	NNS
cord-278081-tk7vn1v1	355	16	due	due	JJ
cord-278081-tk7vn1v1	355	17	to	to	IN
cord-278081-tk7vn1v1	355	18	the	the	DT
cord-278081-tk7vn1v1	355	19	consistency	consistency	NN
cord-278081-tk7vn1v1	355	20	of	of	IN
cord-278081-tk7vn1v1	355	21	inactivation	inactivation	NN
cord-278081-tk7vn1v1	355	22	along	along	IN
cord-278081-tk7vn1v1	355	23	the	the	DT
cord-278081-tk7vn1v1	355	24	mouse	mouse	NN
cord-278081-tk7vn1v1	355	25	X.	X.	NNP
cord-278081-tk7vn1v1	356	1	This	this	DT
cord-278081-tk7vn1v1	356	2	makes	make	VBZ
cord-278081-tk7vn1v1	356	3	the	the	DT
cord-278081-tk7vn1v1	356	4	murine	murine	NN
cord-278081-tk7vn1v1	356	5	X	x	NN
cord-278081-tk7vn1v1	356	6	more	more	RBR
cord-278081-tk7vn1v1	356	7	robust	robust	JJ
cord-278081-tk7vn1v1	356	8	under	under	IN
cord-278081-tk7vn1v1	356	9	stress	stress	NN
cord-278081-tk7vn1v1	356	10	,	,	,
cord-278081-tk7vn1v1	356	11	at	at	IN
cord-278081-tk7vn1v1	356	12	least	least	JJS
cord-278081-tk7vn1v1	356	13	with	with	IN
cord-278081-tk7vn1v1	356	14	regards	regard	NNS
cord-278081-tk7vn1v1	356	15	to	to	IN
cord-278081-tk7vn1v1	356	16	this	this	DT
cord-278081-tk7vn1v1	356	17	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	356	18	(	(	-LRB-
cord-278081-tk7vn1v1	356	19	1	1	CD
cord-278081-tk7vn1v1	356	20	)	)	-RRB-
cord-278081-tk7vn1v1	356	21	.	.	.
cord-278081-tk7vn1v1	357	1	We	-PRON-	PRP
cord-278081-tk7vn1v1	357	2	have	have	VBP
cord-278081-tk7vn1v1	357	3	previously	previously	RB
cord-278081-tk7vn1v1	357	4	discussed	discuss	VBN
cord-278081-tk7vn1v1	357	5	the	the	DT
cord-278081-tk7vn1v1	357	6	short	short	JJ
cord-278081-tk7vn1v1	357	7	arm	arm	NN
cord-278081-tk7vn1v1	357	8	of	of	IN
cord-278081-tk7vn1v1	357	9	the	the	DT
cord-278081-tk7vn1v1	357	10	X	x	NN
cord-278081-tk7vn1v1	357	11	chromosome	chromosome	NN
cord-278081-tk7vn1v1	357	12	(	(	-LRB-
cord-278081-tk7vn1v1	357	13	Xp	Xp	NNP
cord-278081-tk7vn1v1	357	14	)	)	-RRB-
cord-278081-tk7vn1v1	357	15	and	and	CC
cord-278081-tk7vn1v1	357	16	especially	especially	RB
cord-278081-tk7vn1v1	357	17	the	the	DT
cord-278081-tk7vn1v1	357	18	portion	portion	NN
cord-278081-tk7vn1v1	357	19	from	from	IN
cord-278081-tk7vn1v1	357	20	Xp21.2	Xp21.2	VBN
cord-278081-tk7vn1v1	357	21	to	to	IN
cord-278081-tk7vn1v1	357	22	the	the	DT
cord-278081-tk7vn1v1	357	23	terminus	terminus	NN
cord-278081-tk7vn1v1	357	24	as	as	IN
cord-278081-tk7vn1v1	357	25	having	have	VBG
cord-278081-tk7vn1v1	357	26	a	a	DT
cord-278081-tk7vn1v1	357	27	major	major	JJ
cord-278081-tk7vn1v1	357	28	role	role	NN
cord-278081-tk7vn1v1	357	29	in	in	IN
cord-278081-tk7vn1v1	357	30	SLE	SLE	NNP
cord-278081-tk7vn1v1	357	31	,	,	,
cord-278081-tk7vn1v1	357	32	particularly	particularly	RB
cord-278081-tk7vn1v1	357	33	with	with	IN
cord-278081-tk7vn1v1	357	34	regards	regard	NNS
cord-278081-tk7vn1v1	357	35	to	to	IN
cord-278081-tk7vn1v1	357	36	possible	possible	JJ
cord-278081-tk7vn1v1	357	37	reactivation	reactivation	NN
cord-278081-tk7vn1v1	357	38	of	of	IN
cord-278081-tk7vn1v1	357	39	the	the	DT
cord-278081-tk7vn1v1	357	40	inactive	inactive	JJ
cord-278081-tk7vn1v1	357	41	X	x	NN
cord-278081-tk7vn1v1	357	42	chromosome	chromosome	NN
cord-278081-tk7vn1v1	357	43	(	(	-LRB-
cord-278081-tk7vn1v1	357	44	1	1	CD
cord-278081-tk7vn1v1	357	45	-	-	SYM
cord-278081-tk7vn1v1	357	46	3	3	CD
cord-278081-tk7vn1v1	357	47	,	,	,
cord-278081-tk7vn1v1	357	48	72	72	CD
cord-278081-tk7vn1v1	357	49	,	,	,
cord-278081-tk7vn1v1	357	50	82	82	CD
cord-278081-tk7vn1v1	357	51	,	,	,
cord-278081-tk7vn1v1	357	52	106	106	CD
cord-278081-tk7vn1v1	357	53	,	,	,
cord-278081-tk7vn1v1	357	54	107	107	CD
cord-278081-tk7vn1v1	357	55	)	)	-RRB-
cord-278081-tk7vn1v1	357	56	.	.	.
cord-278081-tk7vn1v1	358	1	This	this	DT
cord-278081-tk7vn1v1	358	2	section	section	NN
cord-278081-tk7vn1v1	358	3	includes	include	VBZ
cord-278081-tk7vn1v1	358	4	:	:	:
cord-278081-tk7vn1v1	358	5	a	a	DT
cord-278081-tk7vn1v1	358	6	"	"	``
cord-278081-tk7vn1v1	358	7	hot	hot	JJ
cord-278081-tk7vn1v1	358	8	"	"	''
cord-278081-tk7vn1v1	358	9	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	358	10	(	(	-LRB-
cord-278081-tk7vn1v1	358	11	codes	code	NNS
cord-278081-tk7vn1v1	358	12	for	for	IN
cord-278081-tk7vn1v1	358	13	a	a	DT
cord-278081-tk7vn1v1	358	14	fully	fully	RB
cord-278081-tk7vn1v1	358	15	functional	functional	JJ
cord-278081-tk7vn1v1	358	16	reverse	reverse	NN
cord-278081-tk7vn1v1	358	17	transcriptase	transcriptase	NN
cord-278081-tk7vn1v1	358	18	)	)	-RRB-
cord-278081-tk7vn1v1	358	19	;	;	:
cord-278081-tk7vn1v1	358	20	the	the	DT
cord-278081-tk7vn1v1	358	21	polyamine	polyamine	NN
cord-278081-tk7vn1v1	358	22	genes	gene	NNS
cord-278081-tk7vn1v1	358	23	spermidine	spermidine	NNP
cord-278081-tk7vn1v1	358	24	/	/	SYM
cord-278081-tk7vn1v1	358	25	spermine	spermine	NNP
cord-278081-tk7vn1v1	358	26	N1	N1	NNP
cord-278081-tk7vn1v1	358	27	acetyltransferase	acetyltransferase	NN
cord-278081-tk7vn1v1	358	28	and	and	CC
cord-278081-tk7vn1v1	358	29	SMS	SMS	NNP
cord-278081-tk7vn1v1	358	30	;	;	:
cord-278081-tk7vn1v1	358	31	and	and	CC
cord-278081-tk7vn1v1	358	32	the	the	DT
cord-278081-tk7vn1v1	358	33	PAR1	PAR1	NNP
cord-278081-tk7vn1v1	358	34	region	region	NN
cord-278081-tk7vn1v1	358	35	with	with	IN
cord-278081-tk7vn1v1	358	36	an	an	DT
cord-278081-tk7vn1v1	358	37	abundance	abundance	NN
cord-278081-tk7vn1v1	358	38	of	of	IN
cord-278081-tk7vn1v1	358	39	Alu	Alu	NNP
cord-278081-tk7vn1v1	358	40	elements	element	NNS
cord-278081-tk7vn1v1	358	41	.	.	.
cord-278081-tk7vn1v1	359	1	Other	other	JJ
cord-278081-tk7vn1v1	359	2	groups	group	NNS
cord-278081-tk7vn1v1	359	3	are	be	VBP
cord-278081-tk7vn1v1	359	4	just	just	RB
cord-278081-tk7vn1v1	359	5	now	now	RB
cord-278081-tk7vn1v1	359	6	coming	come	VBG
cord-278081-tk7vn1v1	359	7	to	to	IN
cord-278081-tk7vn1v1	359	8	the	the	DT
cord-278081-tk7vn1v1	359	9	conclusion	conclusion	NN
cord-278081-tk7vn1v1	359	10	that	that	IN
cord-278081-tk7vn1v1	359	11	the	the	DT
cord-278081-tk7vn1v1	359	12	Xp	Xp	NNP
cord-278081-tk7vn1v1	359	13	arm	arm	NN
cord-278081-tk7vn1v1	359	14	has	have	VBZ
cord-278081-tk7vn1v1	359	15	a	a	DT
cord-278081-tk7vn1v1	359	16	major	major	JJ
cord-278081-tk7vn1v1	359	17	role	role	NN
cord-278081-tk7vn1v1	359	18	in	in	IN
cord-278081-tk7vn1v1	359	19	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	359	20	diseases	disease	NNS
cord-278081-tk7vn1v1	359	21	(	(	-LRB-
cord-278081-tk7vn1v1	359	22	108	108	CD
cord-278081-tk7vn1v1	359	23	)	)	-RRB-
cord-278081-tk7vn1v1	359	24	although	although	IN
cord-278081-tk7vn1v1	359	25	they	-PRON-	PRP
cord-278081-tk7vn1v1	359	26	have	have	VBP
cord-278081-tk7vn1v1	359	27	not	not	RB
cord-278081-tk7vn1v1	359	28	mentioned	mention	VBN
cord-278081-tk7vn1v1	359	29	the	the	DT
cord-278081-tk7vn1v1	359	30	Alu	Alu	NNP
cord-278081-tk7vn1v1	359	31	elements	element	NNS
cord-278081-tk7vn1v1	359	32	,	,	,
cord-278081-tk7vn1v1	359	33	LINE-1	LINE-1	NNP
cord-278081-tk7vn1v1	359	34	and	and	CC
cord-278081-tk7vn1v1	359	35	polyamine	polyamine	NN
cord-278081-tk7vn1v1	359	36	genes	gene	NNS
cord-278081-tk7vn1v1	359	37	we	-PRON-	PRP
cord-278081-tk7vn1v1	359	38	have	have	VBP
cord-278081-tk7vn1v1	359	39	mentioned	mention	VBN
cord-278081-tk7vn1v1	359	40	and	and	CC
cord-278081-tk7vn1v1	359	41	they	-PRON-	PRP
cord-278081-tk7vn1v1	359	42	have	have	VBP
cord-278081-tk7vn1v1	359	43	not	not	RB
cord-278081-tk7vn1v1	359	44	made	make	VBN
cord-278081-tk7vn1v1	359	45	the	the	DT
cord-278081-tk7vn1v1	359	46	connection	connection	NN
cord-278081-tk7vn1v1	359	47	to	to	IN
cord-278081-tk7vn1v1	359	48	the	the	DT
cord-278081-tk7vn1v1	359	49	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	359	50	.	.	.
cord-278081-tk7vn1v1	360	1	It	-PRON-	PRP
cord-278081-tk7vn1v1	360	2	is	be	VBZ
cord-278081-tk7vn1v1	360	3	hoped	hope	VBN
cord-278081-tk7vn1v1	360	4	that	that	IN
cord-278081-tk7vn1v1	360	5	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	360	6	disease	disease	NN
cord-278081-tk7vn1v1	360	7	researchers	researcher	NNS
cord-278081-tk7vn1v1	360	8	will	will	MD
cord-278081-tk7vn1v1	360	9	consider	consider	VB
cord-278081-tk7vn1v1	360	10	the	the	DT
cord-278081-tk7vn1v1	360	11	"	"	``
cord-278081-tk7vn1v1	360	12	X	x	NN
cord-278081-tk7vn1v1	360	13	chromosome	chromosome	NN
cord-278081-tk7vn1v1	360	14	-	-	HYPH
cord-278081-tk7vn1v1	360	15	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	360	16	nexus	nexus	NN
cord-278081-tk7vn1v1	360	17	"	"	''
cord-278081-tk7vn1v1	360	18	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	360	19	since	since	IN
cord-278081-tk7vn1v1	360	20	it	-PRON-	PRP
cord-278081-tk7vn1v1	360	21	is	be	VBZ
cord-278081-tk7vn1v1	360	22	the	the	DT
cord-278081-tk7vn1v1	360	23	most	most	RBS
cord-278081-tk7vn1v1	360	24	comprehensive	comprehensive	JJ
cord-278081-tk7vn1v1	360	25	explanation	explanation	NN
cord-278081-tk7vn1v1	360	26	yet	yet	RB
cord-278081-tk7vn1v1	360	27	for	for	IN
cord-278081-tk7vn1v1	360	28	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	360	29	diseases	disease	NNS
cord-278081-tk7vn1v1	360	30	.	.	.
cord-278081-tk7vn1v1	361	1	It	-PRON-	PRP
cord-278081-tk7vn1v1	361	2	does	do	VBZ
cord-278081-tk7vn1v1	361	3	involve	involve	VB
cord-278081-tk7vn1v1	361	4	areas	area	NNS
cord-278081-tk7vn1v1	361	5	with	with	IN
cord-278081-tk7vn1v1	361	6	which	which	WDT
cord-278081-tk7vn1v1	361	7	those	those	DT
cord-278081-tk7vn1v1	361	8	researchers	researcher	NNS
cord-278081-tk7vn1v1	361	9	may	may	MD
cord-278081-tk7vn1v1	361	10	not	not	RB
cord-278081-tk7vn1v1	361	11	be	be	VB
cord-278081-tk7vn1v1	361	12	familiar	familiar	JJ
cord-278081-tk7vn1v1	361	13	,	,	,
cord-278081-tk7vn1v1	361	14	such	such	JJ
cord-278081-tk7vn1v1	361	15	as	as	IN
cord-278081-tk7vn1v1	361	16	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	361	17	,	,	,
cord-278081-tk7vn1v1	361	18	X	x	NN
cord-278081-tk7vn1v1	361	19	inactivation	inactivation	NN
cord-278081-tk7vn1v1	361	20	,	,	,
cord-278081-tk7vn1v1	361	21	epigenetics	epigenetic	NNS
cord-278081-tk7vn1v1	361	22	,	,	,
cord-278081-tk7vn1v1	361	23	and	and	CC
cord-278081-tk7vn1v1	361	24	the	the	DT
cord-278081-tk7vn1v1	361	25	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	361	26	making	make	VBG
cord-278081-tk7vn1v1	361	27	it	-PRON-	PRP
cord-278081-tk7vn1v1	361	28	a	a	DT
cord-278081-tk7vn1v1	361	29	rather	rather	RB
cord-278081-tk7vn1v1	361	30	complex	complex	JJ
cord-278081-tk7vn1v1	361	31	scenario	scenario	NN
cord-278081-tk7vn1v1	361	32	but	but	CC
cord-278081-tk7vn1v1	361	33	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	361	34	diseases	disease	NNS
cord-278081-tk7vn1v1	361	35	are	be	VBP
cord-278081-tk7vn1v1	361	36	very	very	RB
cord-278081-tk7vn1v1	361	37	complex	complex	JJ
cord-278081-tk7vn1v1	361	38	phenomena	phenomenon	NNS
cord-278081-tk7vn1v1	361	39	.	.	.
cord-278081-tk7vn1v1	362	1	The	the	DT
cord-278081-tk7vn1v1	362	2	author	author	NN
cord-278081-tk7vn1v1	362	3	confirms	confirm	VBZ
cord-278081-tk7vn1v1	362	4	being	be	VBG
cord-278081-tk7vn1v1	362	5	the	the	DT
cord-278081-tk7vn1v1	362	6	sole	sole	JJ
cord-278081-tk7vn1v1	362	7	contributor	contributor	NN
cord-278081-tk7vn1v1	362	8	of	of	IN
cord-278081-tk7vn1v1	362	9	this	this	DT
cord-278081-tk7vn1v1	362	10	work	work	NN
cord-278081-tk7vn1v1	362	11	and	and	CC
cord-278081-tk7vn1v1	362	12	approved	approve	VBD
cord-278081-tk7vn1v1	362	13	it	-PRON-	PRP
cord-278081-tk7vn1v1	362	14	for	for	IN
cord-278081-tk7vn1v1	362	15	publication	publication	NN
cord-278081-tk7vn1v1	362	16	.	.	.
cord-278081-tk7vn1v1	363	1	The	the	DT
cord-278081-tk7vn1v1	363	2	author	author	NN
cord-278081-tk7vn1v1	363	3	has	have	VBZ
cord-278081-tk7vn1v1	363	4	no	no	DT
cord-278081-tk7vn1v1	363	5	funding	funding	NN
cord-278081-tk7vn1v1	363	6	other	other	JJ
cord-278081-tk7vn1v1	363	7	than	than	IN
cord-278081-tk7vn1v1	363	8	as	as	IN
cord-278081-tk7vn1v1	363	9	a	a	DT
cord-278081-tk7vn1v1	363	10	Research	Research	NNP
cord-278081-tk7vn1v1	363	11	Assistant	Assistant	NNP
cord-278081-tk7vn1v1	363	12	Professor	Professor	NNP
cord-278081-tk7vn1v1	363	13	in	in	IN
cord-278081-tk7vn1v1	363	14	the	the	DT
cord-278081-tk7vn1v1	363	15	Chemistry	Chemistry	NNP
cord-278081-tk7vn1v1	363	16	Department	Department	NNP
cord-278081-tk7vn1v1	363	17	at	at	IN
cord-278081-tk7vn1v1	363	18	the	the	DT
cord-278081-tk7vn1v1	363	19	University	University	NNP
cord-278081-tk7vn1v1	363	20	of	of	IN
cord-278081-tk7vn1v1	363	21	South	South	NNP
cord-278081-tk7vn1v1	363	22	Florida	Florida	NNP
cord-278081-tk7vn1v1	363	23	,	,	,
cord-278081-tk7vn1v1	363	24	Tampa	Tampa	NNP
cord-278081-tk7vn1v1	363	25	,	,	,
cord-278081-tk7vn1v1	363	26	FL	FL	NNP
cord-278081-tk7vn1v1	363	27	USA	USA	NNP
cord-278081-tk7vn1v1	363	28	.	.	.
cord-278081-tk7vn1v1	363	29	 	 	_SP
cord-278081-tk7vn1v1	364	1	Epigenetics	epigenetic	NNS
cord-278081-tk7vn1v1	364	2	and	and	CC
cord-278081-tk7vn1v1	364	3	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	364	4	diseases	disease	NNS
cord-278081-tk7vn1v1	364	5	:	:	:
cord-278081-tk7vn1v1	364	6	the	the	DT
cord-278081-tk7vn1v1	364	7	X	x	NN
cord-278081-tk7vn1v1	364	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	364	9	-	-	HYPH
cord-278081-tk7vn1v1	364	10	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	365	1	nexus	nexus	NNP
cord-278081-tk7vn1v1	365	2	A	a	DT
cord-278081-tk7vn1v1	365	3	review	review	NN
cord-278081-tk7vn1v1	365	4	of	of	IN
cord-278081-tk7vn1v1	365	5	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	365	6	disease	disease	NN
cord-278081-tk7vn1v1	365	7	hypotheses	hypothesis	NNS
cord-278081-tk7vn1v1	365	8	with	with	IN
cord-278081-tk7vn1v1	365	9	introduction	introduction	NN
cord-278081-tk7vn1v1	365	10	of	of	IN
cord-278081-tk7vn1v1	365	11	the	the	DT
cord-278081-tk7vn1v1	365	12	"	"	``
cord-278081-tk7vn1v1	365	13	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	365	14	"	"	''
cord-278081-tk7vn1v1	365	15	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	366	1	The	the	DT
cord-278081-tk7vn1v1	366	2	'	'	``
cord-278081-tk7vn1v1	366	3	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	366	4	'	'	''
cord-278081-tk7vn1v1	366	5	hypothesis	hypothesis	NN
cord-278081-tk7vn1v1	366	6	of	of	IN
cord-278081-tk7vn1v1	366	7	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	366	8	diseases	disease	NNS
cord-278081-tk7vn1v1	366	9	and	and	CC
cord-278081-tk7vn1v1	366	10	its	-PRON-	PRP$
cord-278081-tk7vn1v1	366	11	implications	implication	NNS
cord-278081-tk7vn1v1	366	12	Tracing	trace	VBG
cord-278081-tk7vn1v1	366	13	environmental	environmental	JJ
cord-278081-tk7vn1v1	366	14	markers	marker	NNS
cord-278081-tk7vn1v1	366	15	of	of	IN
cord-278081-tk7vn1v1	366	16	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	366	17	:	:	:
cord-278081-tk7vn1v1	366	18	introducing	introduce	VBG
cord-278081-tk7vn1v1	366	19	the	the	DT
cord-278081-tk7vn1v1	366	20	infectome	infectome	JJ
cord-278081-tk7vn1v1	366	21	Multiple	multiple	JJ
cord-278081-tk7vn1v1	366	22	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	366	23	after	after	IN
cord-278081-tk7vn1v1	366	24	Iinfectious	Iinfectious	NNP
cord-278081-tk7vn1v1	366	25	mononucleosis	mononucleosis	NN
cord-278081-tk7vn1v1	366	26	Immunoreactivation	Immunoreactivation	NNP
cord-278081-tk7vn1v1	366	27	of	of	IN
cord-278081-tk7vn1v1	366	28	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	366	29	-	-	HYPH
cord-278081-tk7vn1v1	366	30	Barr	Barr	NNP
cord-278081-tk7vn1v1	366	31	virus	virus	NN
cord-278081-tk7vn1v1	366	32	due	due	IN
cord-278081-tk7vn1v1	366	33	to	to	IN
cord-278081-tk7vn1v1	366	34	cytomegalovirus	cytomegalovirus	JJ
cord-278081-tk7vn1v1	366	35	primary	primary	JJ
cord-278081-tk7vn1v1	366	36	infection	infection	NN
cord-278081-tk7vn1v1	367	1	The	the	DT
cord-278081-tk7vn1v1	367	2	extracellular	extracellular	JJ
cord-278081-tk7vn1v1	367	3	domain	domain	NN
cord-278081-tk7vn1v1	367	4	of	of	IN
cord-278081-tk7vn1v1	367	5	the	the	DT
cord-278081-tk7vn1v1	367	6	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	367	7	-	-	HYPH
cord-278081-tk7vn1v1	367	8	Barr	Barr	NNP
cord-278081-tk7vn1v1	367	9	virus	virus	NN
cord-278081-tk7vn1v1	368	1	BZLF2	BZLF2	NNP
cord-278081-tk7vn1v1	368	2	protein	protein	NN
cord-278081-tk7vn1v1	368	3	binds	bind	VBZ
cord-278081-tk7vn1v1	368	4	the	the	DT
cord-278081-tk7vn1v1	368	5	HLA	HLA	NNP
cord-278081-tk7vn1v1	368	6	-	-	HYPH
cord-278081-tk7vn1v1	368	7	DR	DR	NNP
cord-278081-tk7vn1v1	368	8	beta	beta	NN
cord-278081-tk7vn1v1	368	9	chain	chain	NN
cord-278081-tk7vn1v1	368	10	and	and	CC
cord-278081-tk7vn1v1	368	11	inhibits	inhibit	VBZ
cord-278081-tk7vn1v1	368	12	antigen	antigen	NN
cord-278081-tk7vn1v1	368	13	presentation	presentation	NN
cord-278081-tk7vn1v1	369	1	Coxsackievirus	Coxsackievirus	NNP
cord-278081-tk7vn1v1	369	2	B1	b1	NN
cord-278081-tk7vn1v1	369	3	is	be	VBZ
cord-278081-tk7vn1v1	369	4	associated	associate	VBN
cord-278081-tk7vn1v1	369	5	with	with	IN
cord-278081-tk7vn1v1	369	6	induction	induction	NN
cord-278081-tk7vn1v1	369	7	of	of	IN
cord-278081-tk7vn1v1	369	8	β	β	NN
cord-278081-tk7vn1v1	369	9	-	-	HYPH
cord-278081-tk7vn1v1	369	10	cell	cell	NN
cord-278081-tk7vn1v1	369	11	Frontiers	frontier	NNS
cord-278081-tk7vn1v1	369	12	in	in	IN
cord-278081-tk7vn1v1	369	13	Immunology	Immunology	NNP
cord-278081-tk7vn1v1	369	14	|	|	NNP
cord-278081-tk7vn1v1	369	15	www	www	NN
cord-278081-tk7vn1v1	369	16	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	369	17	that	that	WDT
cord-278081-tk7vn1v1	369	18	portends	portend	VBZ
cord-278081-tk7vn1v1	369	19	type	type	NN
cord-278081-tk7vn1v1	369	20	1	1	CD
cord-278081-tk7vn1v1	369	21	diabetes	diabete	VBZ
cord-278081-tk7vn1v1	369	22	Human	human	JJ
cord-278081-tk7vn1v1	369	23	cytomegalovirus	cytomegalovirus	NNP
cord-278081-tk7vn1v1	369	24	and	and	CC
cord-278081-tk7vn1v1	369	25	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	369	26	disease	disease	NN
cord-278081-tk7vn1v1	369	27	Autoimmune	Autoimmune	NNP
cord-278081-tk7vn1v1	369	28	hepatitis	hepatitis	NNP
cord-278081-tk7vn1v1	369	29	:	:	:
cord-278081-tk7vn1v1	369	30	a	a	DT
cord-278081-tk7vn1v1	369	31	comprehensive	comprehensive	JJ
cord-278081-tk7vn1v1	369	32	review	review	NN
cord-278081-tk7vn1v1	370	1	The	the	DT
cord-278081-tk7vn1v1	370	2	mosaic	mosaic	NN
cord-278081-tk7vn1v1	370	3	of	of	IN
cord-278081-tk7vn1v1	370	4	environment	environment	NN
cord-278081-tk7vn1v1	370	5	involvement	involvement	NN
cord-278081-tk7vn1v1	370	6	in	in	IN
cord-278081-tk7vn1v1	370	7	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	370	8	:	:	:
cord-278081-tk7vn1v1	371	1	the	the	DT
cord-278081-tk7vn1v1	371	2	abrogation	abrogation	NN
cord-278081-tk7vn1v1	371	3	of	of	IN
cord-278081-tk7vn1v1	371	4	viral	viral	JJ
cord-278081-tk7vn1v1	371	5	latency	latency	NN
cord-278081-tk7vn1v1	371	6	by	by	IN
cord-278081-tk7vn1v1	371	7	stress	stress	NN
cord-278081-tk7vn1v1	371	8	,	,	,
cord-278081-tk7vn1v1	371	9	a	a	DT
cord-278081-tk7vn1v1	371	10	non	non	JJ
cord-278081-tk7vn1v1	371	11	-	-	JJ
cord-278081-tk7vn1v1	371	12	infectious	infectious	JJ
cord-278081-tk7vn1v1	371	13	environmental	environmental	JJ
cord-278081-tk7vn1v1	371	14	agent	agent	NN
cord-278081-tk7vn1v1	371	15	,	,	,
cord-278081-tk7vn1v1	371	16	is	be	VBZ
cord-278081-tk7vn1v1	371	17	an	an	DT
cord-278081-tk7vn1v1	371	18	intrinsic	intrinsic	JJ
cord-278081-tk7vn1v1	371	19	prerequisite	prerequisite	JJ
cord-278081-tk7vn1v1	371	20	prelude	prelude	NN
cord-278081-tk7vn1v1	371	21	before	before	IN
cord-278081-tk7vn1v1	371	22	viruses	virus	NNS
cord-278081-tk7vn1v1	371	23	can	can	MD
cord-278081-tk7vn1v1	371	24	rank	rank	VB
cord-278081-tk7vn1v1	371	25	as	as	RB
cord-278081-tk7vn1v1	371	26	infectious	infectious	JJ
cord-278081-tk7vn1v1	371	27	environmental	environmental	JJ
cord-278081-tk7vn1v1	371	28	agents	agent	NNS
cord-278081-tk7vn1v1	371	29	that	that	WDT
cord-278081-tk7vn1v1	371	30	trigger	trigger	VBP
cord-278081-tk7vn1v1	371	31	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	371	32	diseases	disease	NNS
cord-278081-tk7vn1v1	371	33	Correlation	correlation	NN
cord-278081-tk7vn1v1	371	34	between	between	IN
cord-278081-tk7vn1v1	371	35	systemic	systemic	JJ
cord-278081-tk7vn1v1	371	36	lupus	lupus	NN
cord-278081-tk7vn1v1	371	37	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	371	38	and	and	CC
cord-278081-tk7vn1v1	371	39	cytomegalovirus	cytomegalovirus	NN
cord-278081-tk7vn1v1	371	40	infection	infection	NN
cord-278081-tk7vn1v1	371	41	detected	detect	VBN
cord-278081-tk7vn1v1	371	42	by	by	IN
cord-278081-tk7vn1v1	371	43	different	different	JJ
cord-278081-tk7vn1v1	371	44	methods	method	NNS
cord-278081-tk7vn1v1	371	45	Autoimmunity	Autoimmunity	NNP
cord-278081-tk7vn1v1	371	46	in	in	IN
cord-278081-tk7vn1v1	371	47	dengue	dengue	NN
cord-278081-tk7vn1v1	371	48	pathogenesis	pathogenesis	NN
cord-278081-tk7vn1v1	371	49	Expression	expression	NN
cord-278081-tk7vn1v1	371	50	of	of	IN
cord-278081-tk7vn1v1	371	51	innate	innate	JJ
cord-278081-tk7vn1v1	371	52	immunity	immunity	NN
cord-278081-tk7vn1v1	371	53	genes	gene	NNS
cord-278081-tk7vn1v1	371	54	and	and	CC
cord-278081-tk7vn1v1	371	55	damage	damage	NN
cord-278081-tk7vn1v1	371	56	of	of	IN
cord-278081-tk7vn1v1	371	57	primary	primary	JJ
cord-278081-tk7vn1v1	371	58	human	human	JJ
cord-278081-tk7vn1v1	371	59	pancreatic	pancreatic	NN
cord-278081-tk7vn1v1	371	60	islets	islet	NNS
cord-278081-tk7vn1v1	371	61	by	by	IN
cord-278081-tk7vn1v1	371	62	epidemic	epidemic	NN
cord-278081-tk7vn1v1	371	63	strains	strain	NNS
cord-278081-tk7vn1v1	371	64	of	of	IN
cord-278081-tk7vn1v1	371	65	echovirus	echovirus	NNP
cord-278081-tk7vn1v1	371	66	:	:	:
cord-278081-tk7vn1v1	371	67	implication	implication	NN
cord-278081-tk7vn1v1	371	68	for	for	IN
cord-278081-tk7vn1v1	371	69	post	post	JJ
cord-278081-tk7vn1v1	371	70	-	-	JJ
cord-278081-tk7vn1v1	371	71	virus	virus	JJ
cord-278081-tk7vn1v1	371	72	islet	islet	NN
cord-278081-tk7vn1v1	371	73	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	371	74	Systematic	systematic	JJ
cord-278081-tk7vn1v1	371	75	review	review	NN
cord-278081-tk7vn1v1	371	76	and	and	CC
cord-278081-tk7vn1v1	371	77	meta	meta	NN
cord-278081-tk7vn1v1	371	78	-	-	HYPH
cord-278081-tk7vn1v1	371	79	analysis	analysis	NN
cord-278081-tk7vn1v1	371	80	of	of	IN
cord-278081-tk7vn1v1	371	81	the	the	DT
cord-278081-tk7vn1v1	371	82	sero	sero	NNP
cord-278081-tk7vn1v1	371	83	-	-	HYPH
cord-278081-tk7vn1v1	371	84	epidemiological	epidemiological	JJ
cord-278081-tk7vn1v1	371	85	association	association	NN
cord-278081-tk7vn1v1	371	86	between	between	IN
cord-278081-tk7vn1v1	371	87	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	371	88	-	-	HYPH
cord-278081-tk7vn1v1	371	89	Barr	Barr	NNP
cord-278081-tk7vn1v1	371	90	virus	virus	NN
cord-278081-tk7vn1v1	371	91	and	and	CC
cord-278081-tk7vn1v1	371	92	systemic	systemic	JJ
cord-278081-tk7vn1v1	371	93	lupus	lupus	NN
cord-278081-tk7vn1v1	371	94	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	372	1	The	the	DT
cord-278081-tk7vn1v1	372	2	immunology	immunology	NN
cord-278081-tk7vn1v1	372	3	of	of	IN
cord-278081-tk7vn1v1	372	4	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	372	5	-	-	HYPH
cord-278081-tk7vn1v1	372	6	Barr	Barr	NNP
cord-278081-tk7vn1v1	372	7	virus	virus	NN
cord-278081-tk7vn1v1	372	8	-	-	HYPH
cord-278081-tk7vn1v1	372	9	induced	induce	VBN
cord-278081-tk7vn1v1	372	10	disease	disease	NN
cord-278081-tk7vn1v1	372	11	Hepatitis	Hepatitis	NNP
cord-278081-tk7vn1v1	372	12	B	B	NNP
cord-278081-tk7vn1v1	372	13	virus	virus	NN
cord-278081-tk7vn1v1	372	14	(	(	-LRB-
cord-278081-tk7vn1v1	373	1	HBV	HBV	NNP
cord-278081-tk7vn1v1	373	2	)	)	-RRB-
cord-278081-tk7vn1v1	373	3	and	and	CC
cord-278081-tk7vn1v1	373	4	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	373	5	disease	disease	NN
cord-278081-tk7vn1v1	373	6	Hepatitis	Hepatitis	NNP
cord-278081-tk7vn1v1	373	7	C	C	NNP
cord-278081-tk7vn1v1	373	8	virus	virus	NN
cord-278081-tk7vn1v1	373	9	,	,	,
cord-278081-tk7vn1v1	373	10	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	373	11	and	and	CC
cord-278081-tk7vn1v1	373	12	rheumatic	rheumatic	JJ
cord-278081-tk7vn1v1	373	13	disease	disease	NN
cord-278081-tk7vn1v1	373	14	Herpes	Herpes	NNP
cord-278081-tk7vn1v1	373	15	simplex	simplex	NN
cord-278081-tk7vn1v1	373	16	virus	virus	NN
cord-278081-tk7vn1v1	373	17	encephalitis	encephalitis	RB
cord-278081-tk7vn1v1	373	18	is	be	VBZ
cord-278081-tk7vn1v1	373	19	a	a	DT
cord-278081-tk7vn1v1	373	20	trigger	trigger	NN
cord-278081-tk7vn1v1	373	21	of	of	IN
cord-278081-tk7vn1v1	373	22	brain	brain	NN
cord-278081-tk7vn1v1	373	23	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	373	24	Molecular	molecular	JJ
cord-278081-tk7vn1v1	373	25	mimicry	mimicry	NN
cord-278081-tk7vn1v1	373	26	by	by	IN
cord-278081-tk7vn1v1	373	27	herpes	herpes	NN
cord-278081-tk7vn1v1	373	28	simplex	simplex	NNP
cord-278081-tk7vn1v1	373	29	virus	virus	NN
cord-278081-tk7vn1v1	373	30	-	-	HYPH
cord-278081-tk7vn1v1	373	31	type	type	NN
cord-278081-tk7vn1v1	373	32	1	1	CD
cord-278081-tk7vn1v1	373	33	:	:	:
cord-278081-tk7vn1v1	373	34	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	373	35	disease	disease	NN
cord-278081-tk7vn1v1	373	36	after	after	IN
cord-278081-tk7vn1v1	373	37	viral	viral	JJ
cord-278081-tk7vn1v1	373	38	infection	infection	NN
cord-278081-tk7vn1v1	373	39	Autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	373	40	and	and	CC
cord-278081-tk7vn1v1	373	41	dysmetabolism	dysmetabolism	NN
cord-278081-tk7vn1v1	373	42	of	of	IN
cord-278081-tk7vn1v1	373	43	human	human	JJ
cord-278081-tk7vn1v1	373	44	acquired	acquire	VBN
cord-278081-tk7vn1v1	373	45	immunodeficiency	immunodeficiency	NNP
cord-278081-tk7vn1v1	373	46	syndrome	syndrome	NN
cord-278081-tk7vn1v1	373	47	AIDS	AIDS	NNP
cord-278081-tk7vn1v1	373	48	virus	virus	NN
cord-278081-tk7vn1v1	373	49	infection	infection	NN
cord-278081-tk7vn1v1	373	50	and	and	CC
cord-278081-tk7vn1v1	373	51	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	373	52	:	:	:
cord-278081-tk7vn1v1	373	53	a	a	DT
cord-278081-tk7vn1v1	373	54	perspective	perspective	NN
cord-278081-tk7vn1v1	373	55	of	of	IN
cord-278081-tk7vn1v1	373	56	the	the	DT
cord-278081-tk7vn1v1	373	57	clinical	clinical	JJ
cord-278081-tk7vn1v1	373	58	,	,	,
cord-278081-tk7vn1v1	373	59	immunological	immunological	JJ
cord-278081-tk7vn1v1	373	60	,	,	,
cord-278081-tk7vn1v1	373	61	and	and	CC
cord-278081-tk7vn1v1	373	62	molecular	molecular	JJ
cord-278081-tk7vn1v1	373	63	origins	origin	NNS
cord-278081-tk7vn1v1	373	64	of	of	IN
cord-278081-tk7vn1v1	373	65	the	the	DT
cord-278081-tk7vn1v1	373	66	autoallergic	autoallergic	NNP
cord-278081-tk7vn1v1	373	67	pathologies	pathology	NNS
cord-278081-tk7vn1v1	373	68	associated	associate	VBN
cord-278081-tk7vn1v1	373	69	with	with	IN
cord-278081-tk7vn1v1	373	70	HIV	HIV	NNP
cord-278081-tk7vn1v1	373	71	disease	disease	NN
cord-278081-tk7vn1v1	374	1	The	the	DT
cord-278081-tk7vn1v1	374	2	enemy	enemy	NN
cord-278081-tk7vn1v1	374	3	within	within	IN
cord-278081-tk7vn1v1	374	4	:	:	:
cord-278081-tk7vn1v1	374	5	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	374	6	retroelements	retroelement	NNS
cord-278081-tk7vn1v1	374	7	and	and	CC
cord-278081-tk7vn1v1	374	8	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	374	9	disease	disease	NN
cord-278081-tk7vn1v1	374	10	Human	Human	NNP
cord-278081-tk7vn1v1	374	11	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	374	12	retrovirus	retrovirus	NN
cord-278081-tk7vn1v1	374	13	group	group	NN
cord-278081-tk7vn1v1	374	14	E	e	NN
cord-278081-tk7vn1v1	374	15	and	and	CC
cord-278081-tk7vn1v1	374	16	its	-PRON-	PRP$
cord-278081-tk7vn1v1	374	17	involvement	involvement	NN
cord-278081-tk7vn1v1	374	18	in	in	IN
cord-278081-tk7vn1v1	374	19	diseases	disease	NNS
cord-278081-tk7vn1v1	375	1	On	on	IN
cord-278081-tk7vn1v1	375	2	the	the	DT
cord-278081-tk7vn1v1	375	3	relationship	relationship	NN
cord-278081-tk7vn1v1	375	4	between	between	IN
cord-278081-tk7vn1v1	375	5	human	human	JJ
cord-278081-tk7vn1v1	375	6	papilloma	papilloma	NN
cord-278081-tk7vn1v1	375	7	virus	virus	NN
cord-278081-tk7vn1v1	375	8	vaccine	vaccine	NN
cord-278081-tk7vn1v1	375	9	and	and	CC
cord-278081-tk7vn1v1	375	10	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	375	11	diseases	disease	NNS
cord-278081-tk7vn1v1	375	12	Human	human	JJ
cord-278081-tk7vn1v1	375	13	parvovirus	parvovirus	NN
cord-278081-tk7vn1v1	375	14	B19	B19	NNP
cord-278081-tk7vn1v1	375	15	,	,	,
cord-278081-tk7vn1v1	375	16	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	375	17	and	and	CC
cord-278081-tk7vn1v1	375	18	systemic	systemic	JJ
cord-278081-tk7vn1v1	375	19	lupus	lupus	NN
cord-278081-tk7vn1v1	375	20	erythematosus	erythematosu	VBZ
cord-278081-tk7vn1v1	375	21	Human	human	JJ
cord-278081-tk7vn1v1	375	22	parvovirus	parvovirus	NN
cord-278081-tk7vn1v1	375	23	B19	B19	NNP
cord-278081-tk7vn1v1	375	24	infection	infection	NN
cord-278081-tk7vn1v1	375	25	and	and	CC
cord-278081-tk7vn1v1	375	26	autoimmunity	autoimmunity	IN
cord-278081-tk7vn1v1	375	27	Possible	possible	JJ
cord-278081-tk7vn1v1	375	28	role	role	NN
cord-278081-tk7vn1v1	375	29	of	of	IN
cord-278081-tk7vn1v1	375	30	human	human	JJ
cord-278081-tk7vn1v1	375	31	herpesvirus	herpesvirus	NN
cord-278081-tk7vn1v1	375	32	6	6	CD
cord-278081-tk7vn1v1	375	33	as	as	IN
cord-278081-tk7vn1v1	375	34	a	a	DT
cord-278081-tk7vn1v1	375	35	trigger	trigger	NN
cord-278081-tk7vn1v1	375	36	of	of	IN
cord-278081-tk7vn1v1	375	37	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	375	38	disease	disease	NNP
cord-278081-tk7vn1v1	375	39	Association	Association	NNP
cord-278081-tk7vn1v1	375	40	of	of	IN
cord-278081-tk7vn1v1	375	41	human	human	JJ
cord-278081-tk7vn1v1	375	42	herpes	herpes	NNP
cord-278081-tk7vn1v1	375	43	virus	virus	NN
cord-278081-tk7vn1v1	375	44	6	6	CD
cord-278081-tk7vn1v1	375	45	(	(	-LRB-
cord-278081-tk7vn1v1	375	46	HHV-6	HHV-6	NNP
cord-278081-tk7vn1v1	375	47	)	)	-RRB-
cord-278081-tk7vn1v1	375	48	with	with	IN
cord-278081-tk7vn1v1	375	49	multiple	multiple	JJ
cord-278081-tk7vn1v1	375	50	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	51	:	:	:
cord-278081-tk7vn1v1	375	52	increased	increase	VBN
cord-278081-tk7vn1v1	375	53	IgM	IgM	NNP
cord-278081-tk7vn1v1	375	54	response	response	NN
cord-278081-tk7vn1v1	375	55	to	to	IN
cord-278081-tk7vn1v1	375	56	HHV-6	HHV-6	NNP
cord-278081-tk7vn1v1	375	57	early	early	JJ
cord-278081-tk7vn1v1	375	58	antigen	antigen	NN
cord-278081-tk7vn1v1	375	59	and	and	CC
cord-278081-tk7vn1v1	375	60	detection	detection	NN
cord-278081-tk7vn1v1	375	61	of	of	IN
cord-278081-tk7vn1v1	375	62	serum	serum	NN
cord-278081-tk7vn1v1	375	63	HHV-6	HHV-6	NNP
cord-278081-tk7vn1v1	375	64	DNA	DNA	NNP
cord-278081-tk7vn1v1	375	65	Virus	virus	NN
cord-278081-tk7vn1v1	375	66	infection	infection	NN
cord-278081-tk7vn1v1	375	67	,	,	,
cord-278081-tk7vn1v1	375	68	antiviral	antiviral	JJ
cord-278081-tk7vn1v1	375	69	immunity	immunity	NN
cord-278081-tk7vn1v1	375	70	,	,	,
cord-278081-tk7vn1v1	375	71	and	and	CC
cord-278081-tk7vn1v1	375	72	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	375	73	Increased	increase	VBN
cord-278081-tk7vn1v1	375	74	prevalence	prevalence	NN
cord-278081-tk7vn1v1	375	75	of	of	IN
cord-278081-tk7vn1v1	375	76	varicella	varicella	NN
cord-278081-tk7vn1v1	375	77	zoster	zoster	NN
cord-278081-tk7vn1v1	375	78	virus	virus	NN
cord-278081-tk7vn1v1	375	79	DNA	dna	NN
cord-278081-tk7vn1v1	375	80	in	in	IN
cord-278081-tk7vn1v1	375	81	cerebrospinal	cerebrospinal	JJ
cord-278081-tk7vn1v1	375	82	fluid	fluid	NN
cord-278081-tk7vn1v1	375	83	from	from	IN
cord-278081-tk7vn1v1	375	84	patients	patient	NNS
cord-278081-tk7vn1v1	375	85	with	with	IN
cord-278081-tk7vn1v1	375	86	multiple	multiple	JJ
cord-278081-tk7vn1v1	375	87	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	88	West	West	NNP
cord-278081-tk7vn1v1	375	89	Nile	Nile	NNP
cord-278081-tk7vn1v1	375	90	virus	virus	NN
cord-278081-tk7vn1v1	375	91	infection	infection	NN
cord-278081-tk7vn1v1	375	92	and	and	CC
cord-278081-tk7vn1v1	375	93	myasthenia	myasthenia	NN
cord-278081-tk7vn1v1	375	94	gravis	gravis	NN
cord-278081-tk7vn1v1	375	95	Zika	Zika	NNP
cord-278081-tk7vn1v1	375	96	virus	virus	NN
cord-278081-tk7vn1v1	375	97	and	and	CC
cord-278081-tk7vn1v1	375	98	neurologic	neurologic	JJ
cord-278081-tk7vn1v1	375	99	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	375	100	:	:	:
cord-278081-tk7vn1v1	375	101	the	the	DT
cord-278081-tk7vn1v1	375	102	putative	putative	JJ
cord-278081-tk7vn1v1	375	103	role	role	NN
cord-278081-tk7vn1v1	375	104	of	of	IN
cord-278081-tk7vn1v1	375	105	gangliosides	ganglioside	NNS
cord-278081-tk7vn1v1	375	106	Classification	classification	NN
cord-278081-tk7vn1v1	375	107	and	and	CC
cord-278081-tk7vn1v1	375	108	characterization	characterization	NN
cord-278081-tk7vn1v1	375	109	of	of	IN
cord-278081-tk7vn1v1	375	110	human	human	JJ
cord-278081-tk7vn1v1	375	111	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	375	112	retroviruses	retrovirus	NNS
cord-278081-tk7vn1v1	375	113	;	;	,
cord-278081-tk7vn1v1	375	114	mosaic	mosaic	JJ
cord-278081-tk7vn1v1	375	115	forms	form	NNS
cord-278081-tk7vn1v1	375	116	are	be	VBP
cord-278081-tk7vn1v1	375	117	common	common	JJ
cord-278081-tk7vn1v1	375	118	Measles	Measles	NNP
cord-278081-tk7vn1v1	375	119	virus	virus	NN
cord-278081-tk7vn1v1	375	120	antibodies	antibody	NNS
cord-278081-tk7vn1v1	375	121	in	in	IN
cord-278081-tk7vn1v1	375	122	serum	serum	NN
cord-278081-tk7vn1v1	375	123	and	and	CC
cord-278081-tk7vn1v1	375	124	cerebrospinal	cerebrospinal	JJ
cord-278081-tk7vn1v1	375	125	fluid	fluid	NN
cord-278081-tk7vn1v1	375	126	in	in	IN
cord-278081-tk7vn1v1	375	127	patients	patient	NNS
cord-278081-tk7vn1v1	375	128	with	with	IN
cord-278081-tk7vn1v1	375	129	multiple	multiple	JJ
cord-278081-tk7vn1v1	375	130	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	131	and	and	CC
cord-278081-tk7vn1v1	375	132	other	other	JJ
cord-278081-tk7vn1v1	375	133	neurological	neurological	JJ
cord-278081-tk7vn1v1	375	134	disorders	disorder	NNS
cord-278081-tk7vn1v1	375	135	,	,	,
cord-278081-tk7vn1v1	375	136	with	with	IN
cord-278081-tk7vn1v1	375	137	special	special	JJ
cord-278081-tk7vn1v1	375	138	reference	reference	NN
cord-278081-tk7vn1v1	375	139	to	to	IN
cord-278081-tk7vn1v1	375	140	measles	measles	NNP
cord-278081-tk7vn1v1	375	141	antibody	antibody	NN
cord-278081-tk7vn1v1	375	142	synthesis	synthesis	NN
cord-278081-tk7vn1v1	375	143	within	within	IN
cord-278081-tk7vn1v1	375	144	the	the	DT
cord-278081-tk7vn1v1	375	145	central	central	JJ
cord-278081-tk7vn1v1	375	146	nervous	nervous	JJ
cord-278081-tk7vn1v1	375	147	system	system	NN
cord-278081-tk7vn1v1	375	148	Multiple	multiple	JJ
cord-278081-tk7vn1v1	375	149	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	150	incidence	incidence	NN
cord-278081-tk7vn1v1	375	151	in	in	IN
cord-278081-tk7vn1v1	375	152	the	the	DT
cord-278081-tk7vn1v1	375	153	era	era	NN
cord-278081-tk7vn1v1	375	154	of	of	IN
cord-278081-tk7vn1v1	375	155	measles	measles	NN
cord-278081-tk7vn1v1	375	156	-	-	HYPH
cord-278081-tk7vn1v1	375	157	mumps	mumps	NN
cord-278081-tk7vn1v1	375	158	-	-	HYPH
cord-278081-tk7vn1v1	375	159	rubella	rubella	NN
cord-278081-tk7vn1v1	375	160	mass	mass	NN
cord-278081-tk7vn1v1	375	161	vaccinations	vaccination	NNS
cord-278081-tk7vn1v1	375	162	Varicella	varicella	NN
cord-278081-tk7vn1v1	375	163	-	-	HYPH
cord-278081-tk7vn1v1	375	164	zoster	zoster	NN
cord-278081-tk7vn1v1	375	165	virus	virus	NN
cord-278081-tk7vn1v1	375	166	in	in	IN
cord-278081-tk7vn1v1	375	167	cerebrospinal	cerebrospinal	JJ
cord-278081-tk7vn1v1	375	168	fluid	fluid	NN
cord-278081-tk7vn1v1	375	169	at	at	IN
cord-278081-tk7vn1v1	375	170	relapses	relapse	NNS
cord-278081-tk7vn1v1	375	171	of	of	IN
cord-278081-tk7vn1v1	375	172	multiple	multiple	JJ
cord-278081-tk7vn1v1	375	173	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	174	Viruses	virus	NNS
cord-278081-tk7vn1v1	375	175	and	and	CC
cord-278081-tk7vn1v1	375	176	endogenous	endogenous	JJ
cord-278081-tk7vn1v1	375	177	retroviruses	retrovirus	NNS
cord-278081-tk7vn1v1	375	178	in	in	IN
cord-278081-tk7vn1v1	375	179	multiple	multiple	JJ
cord-278081-tk7vn1v1	375	180	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	375	181	:	:	:
cord-278081-tk7vn1v1	375	182	from	from	IN
cord-278081-tk7vn1v1	375	183	correlation	correlation	NN
cord-278081-tk7vn1v1	375	184	to	to	IN
cord-278081-tk7vn1v1	375	185	causation	causation	NN
cord-278081-tk7vn1v1	375	186	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	375	187	-	-	HYPH
cord-278081-tk7vn1v1	375	188	Barr	Barr	NNP
cord-278081-tk7vn1v1	375	189	virus	virus	NN
cord-278081-tk7vn1v1	375	190	in	in	IN
cord-278081-tk7vn1v1	375	191	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	375	192	diseases	disease	NNS
cord-278081-tk7vn1v1	376	1	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	376	2	-	-	HYPH
cord-278081-tk7vn1v1	376	3	Barr	Barr	NNP
cord-278081-tk7vn1v1	376	4	virus	virus	NN
cord-278081-tk7vn1v1	376	5	and	and	CC
cord-278081-tk7vn1v1	376	6	systemic	systemic	JJ
cord-278081-tk7vn1v1	376	7	lupus	lupus	NN
cord-278081-tk7vn1v1	376	8	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	376	9	Strong	strong	JJ
cord-278081-tk7vn1v1	376	10	viral	viral	JJ
cord-278081-tk7vn1v1	376	11	associations	association	NNS
cord-278081-tk7vn1v1	376	12	with	with	IN
cord-278081-tk7vn1v1	376	13	SLE	SLE	NNP
cord-278081-tk7vn1v1	376	14	among	among	IN
cord-278081-tk7vn1v1	376	15	Filipinos	Filipinos	NNPS
cord-278081-tk7vn1v1	377	1	The	the	DT
cord-278081-tk7vn1v1	377	2	role	role	NN
cord-278081-tk7vn1v1	377	3	of	of	IN
cord-278081-tk7vn1v1	377	4	EBV	EBV	NNP
cord-278081-tk7vn1v1	377	5	in	in	IN
cord-278081-tk7vn1v1	377	6	MS	MS	NNP
cord-278081-tk7vn1v1	377	7	pathogenesis	pathogenesis	NN
cord-278081-tk7vn1v1	377	8	Potential	potential	JJ
cord-278081-tk7vn1v1	377	9	role	role	NN
cord-278081-tk7vn1v1	377	10	of	of	IN
cord-278081-tk7vn1v1	377	11	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	377	12	-	-	HYPH
cord-278081-tk7vn1v1	377	13	Barr	Barr	NNP
cord-278081-tk7vn1v1	377	14	virus	virus	NN
cord-278081-tk7vn1v1	377	15	in	in	IN
cord-278081-tk7vn1v1	377	16	Sjogren	Sjogren	NNP
cord-278081-tk7vn1v1	377	17	's	's	POS
cord-278081-tk7vn1v1	377	18	syndrome	syndrome	NN
cord-278081-tk7vn1v1	377	19	and	and	CC
cord-278081-tk7vn1v1	377	20	rheumatoid	rheumatoid	NN
cord-278081-tk7vn1v1	377	21	arthritis	arthritis	NN
cord-278081-tk7vn1v1	378	1	An	an	DT
cord-278081-tk7vn1v1	378	2	updated	update	VBN
cord-278081-tk7vn1v1	378	3	meta	meta	NN
cord-278081-tk7vn1v1	378	4	-	-	HYPH
cord-278081-tk7vn1v1	378	5	analysis	analysis	NN
cord-278081-tk7vn1v1	378	6	of	of	IN
cord-278081-tk7vn1v1	378	7	risk	risk	NN
cord-278081-tk7vn1v1	378	8	of	of	IN
cord-278081-tk7vn1v1	378	9	multiple	multiple	JJ
cord-278081-tk7vn1v1	378	10	sclerosis	sclerosis	NN
cord-278081-tk7vn1v1	378	11	following	follow	VBG
cord-278081-tk7vn1v1	378	12	infectious	infectious	JJ
cord-278081-tk7vn1v1	378	13	mononucleosis	mononucleosis	NN
cord-278081-tk7vn1v1	379	1	The	the	DT
cord-278081-tk7vn1v1	379	2	DNA	dna	NN
cord-278081-tk7vn1v1	379	3	sequence	sequence	NN
cord-278081-tk7vn1v1	379	4	of	of	IN
cord-278081-tk7vn1v1	379	5	the	the	DT
cord-278081-tk7vn1v1	379	6	human	human	JJ
cord-278081-tk7vn1v1	379	7	X	X	NNP
cord-278081-tk7vn1v1	379	8	chromosome	chromosome	NN
cord-278081-tk7vn1v1	379	9	Nuclear	nuclear	JJ
cord-278081-tk7vn1v1	379	10	entry	entry	NN
cord-278081-tk7vn1v1	379	11	of	of	IN
cord-278081-tk7vn1v1	379	12	DNA	dna	NN
cord-278081-tk7vn1v1	379	13	viruses	virus	NNS
cord-278081-tk7vn1v1	379	14	Identification	identification	NN
cord-278081-tk7vn1v1	379	15	and	and	CC
cord-278081-tk7vn1v1	379	16	characterization	characterization	NN
cord-278081-tk7vn1v1	379	17	of	of	IN
cord-278081-tk7vn1v1	379	18	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	379	19	and	and	CC
cord-278081-tk7vn1v1	379	20	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	379	21	localization	localization	NN
cord-278081-tk7vn1v1	379	22	signals	signal	NNS
cord-278081-tk7vn1v1	379	23	in	in	IN
cord-278081-tk7vn1v1	379	24	the	the	DT
cord-278081-tk7vn1v1	379	25	adeno	adeno	NN
cord-278081-tk7vn1v1	379	26	-	-	HYPH
cord-278081-tk7vn1v1	379	27	associated	associate	VBN
cord-278081-tk7vn1v1	379	28	virus	virus	NN
cord-278081-tk7vn1v1	379	29	serotype	serotype	NN
cord-278081-tk7vn1v1	379	30	2	2	CD
cord-278081-tk7vn1v1	379	31	assembly	assembly	NN
cord-278081-tk7vn1v1	379	32	-	-	HYPH
cord-278081-tk7vn1v1	379	33	activating	activate	VBG
cord-278081-tk7vn1v1	379	34	protein	protein	NN
cord-278081-tk7vn1v1	379	35	Delineation	delineation	NN
cord-278081-tk7vn1v1	379	36	and	and	CC
cord-278081-tk7vn1v1	379	37	modelling	modelling	NN
cord-278081-tk7vn1v1	379	38	of	of	IN
cord-278081-tk7vn1v1	379	39	a	a	DT
cord-278081-tk7vn1v1	379	40	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	379	41	retention	retention	NN
cord-278081-tk7vn1v1	379	42	signal	signal	NN
cord-278081-tk7vn1v1	379	43	in	in	IN
cord-278081-tk7vn1v1	379	44	the	the	DT
cord-278081-tk7vn1v1	379	45	coronavirus	coronavirus	NN
cord-278081-tk7vn1v1	379	46	nucleocapsid	nucleocapsid	NN
cord-278081-tk7vn1v1	379	47	protein	protein	NN
cord-278081-tk7vn1v1	379	48	New	new	JJ
cord-278081-tk7vn1v1	379	49	insights	insight	NNS
cord-278081-tk7vn1v1	379	50	into	into	IN
cord-278081-tk7vn1v1	379	51	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	379	52	structure	structure	NN
cord-278081-tk7vn1v1	379	53	and	and	CC
cord-278081-tk7vn1v1	379	54	function	function	NN
cord-278081-tk7vn1v1	379	55	.	.	.
cord-278081-tk7vn1v1	380	1	F1000Prime	F1000Prime	NNP
cord-278081-tk7vn1v1	380	2	Rep	Rep	NNP
cord-278081-tk7vn1v1	380	3	The	the	DT
cord-278081-tk7vn1v1	380	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	380	5	:	:	:
cord-278081-tk7vn1v1	380	6	structure	structure	NN
cord-278081-tk7vn1v1	380	7	/	/	SYM
cord-278081-tk7vn1v1	380	8	function	function	NN
cord-278081-tk7vn1v1	380	9	relationship	relationship	NN
cord-278081-tk7vn1v1	380	10	in	in	IN
cord-278081-tk7vn1v1	380	11	RNA	RNA	NNP
cord-278081-tk7vn1v1	380	12	metabolism	metabolism	NN
cord-278081-tk7vn1v1	380	13	Nucleolus	Nucleolus	NNP
cord-278081-tk7vn1v1	380	14	and	and	CC
cord-278081-tk7vn1v1	380	15	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	380	16	periphery	periphery	NN
cord-278081-tk7vn1v1	380	17	:	:	:
cord-278081-tk7vn1v1	380	18	velcro	velcro	NN
cord-278081-tk7vn1v1	380	19	for	for	IN
cord-278081-tk7vn1v1	380	20	heterochromatin	heterochromatin	NN
cord-278081-tk7vn1v1	380	21	Proteins	protein	NNS
cord-278081-tk7vn1v1	380	22	of	of	IN
cord-278081-tk7vn1v1	380	23	the	the	DT
cord-278081-tk7vn1v1	380	24	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	380	25	:	:	:
cord-278081-tk7vn1v1	380	26	an	an	DT
cord-278081-tk7vn1v1	380	27	introduction	introduction	NN
cord-278081-tk7vn1v1	380	28	The	the	DT
cord-278081-tk7vn1v1	380	29	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	380	30	-guardian	-guardian	NN
cord-278081-tk7vn1v1	380	31	of	of	IN
cord-278081-tk7vn1v1	380	32	cellular	cellular	JJ
cord-278081-tk7vn1v1	380	33	homeostasis	homeostasis	NN
cord-278081-tk7vn1v1	380	34	and	and	CC
cord-278081-tk7vn1v1	380	35	genome	genome	NN
cord-278081-tk7vn1v1	380	36	integrity	integrity	NN
cord-278081-tk7vn1v1	380	37	Crosstalk	crosstalk	NN
cord-278081-tk7vn1v1	380	38	between	between	IN
cord-278081-tk7vn1v1	380	39	the	the	DT
cord-278081-tk7vn1v1	380	40	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	380	41	and	and	CC
cord-278081-tk7vn1v1	380	42	the	the	DT
cord-278081-tk7vn1v1	380	43	DNA	dna	NN
cord-278081-tk7vn1v1	380	44	damage	damage	NN
cord-278081-tk7vn1v1	380	45	response	response	NN
cord-278081-tk7vn1v1	380	46	Nucleolar	Nucleolar	NNP
cord-278081-tk7vn1v1	380	47	DNA	DNA	NNP
cord-278081-tk7vn1v1	380	48	:	:	:
cord-278081-tk7vn1v1	380	49	the	the	DT
cord-278081-tk7vn1v1	380	50	host	host	NN
cord-278081-tk7vn1v1	380	51	and	and	CC
cord-278081-tk7vn1v1	380	52	guests	guest	NNS
cord-278081-tk7vn1v1	380	53	Perinucleolar	Perinucleolar	NNP
cord-278081-tk7vn1v1	380	54	targeting	target	VBG
cord-278081-tk7vn1v1	380	55	of	of	IN
cord-278081-tk7vn1v1	380	56	the	the	DT
cord-278081-tk7vn1v1	380	57	inactive	inactive	JJ
cord-278081-tk7vn1v1	380	58	X	x	NN
cord-278081-tk7vn1v1	380	59	during	during	IN
cord-278081-tk7vn1v1	380	60	S	s	NN
cord-278081-tk7vn1v1	380	61	phase	phase	NN
cord-278081-tk7vn1v1	380	62	:	:	:
cord-278081-tk7vn1v1	380	63	evidence	evidence	NN
cord-278081-tk7vn1v1	380	64	for	for	IN
cord-278081-tk7vn1v1	380	65	a	a	DT
cord-278081-tk7vn1v1	380	66	role	role	NN
cord-278081-tk7vn1v1	380	67	in	in	IN
cord-278081-tk7vn1v1	380	68	the	the	DT
cord-278081-tk7vn1v1	380	69	maintenance	maintenance	NN
cord-278081-tk7vn1v1	380	70	of	of	IN
cord-278081-tk7vn1v1	380	71	silencing	silence	VBG
cord-278081-tk7vn1v1	380	72	Regulation	regulation	NN
cord-278081-tk7vn1v1	380	73	of	of	IN
cord-278081-tk7vn1v1	380	74	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	380	75	-	-	HYPH
cord-278081-tk7vn1v1	380	76	Barr	Barr	NNP
cord-278081-tk7vn1v1	380	77	virus	virus	NN
cord-278081-tk7vn1v1	380	78	latency	latency	NN
cord-278081-tk7vn1v1	380	79	type	type	NN
cord-278081-tk7vn1v1	380	80	by	by	IN
cord-278081-tk7vn1v1	380	81	the	the	DT
cord-278081-tk7vn1v1	380	82	chromatin	chromatin	NN
cord-278081-tk7vn1v1	380	83	boundary	boundary	NN
cord-278081-tk7vn1v1	380	84	factor	factor	NN
cord-278081-tk7vn1v1	380	85	CTCF	CTCF	NNP
cord-278081-tk7vn1v1	380	86	Alu	Alu	NNP
cord-278081-tk7vn1v1	380	87	element	element	NN
cord-278081-tk7vn1v1	380	88	-	-	HYPH
cord-278081-tk7vn1v1	380	89	containing	contain	VBG
cord-278081-tk7vn1v1	380	90	RNAs	rna	NNS
cord-278081-tk7vn1v1	380	91	maintain	maintain	VBP
cord-278081-tk7vn1v1	380	92	nucleolar	nucleolar	JJ
cord-278081-tk7vn1v1	380	93	structure	structure	NN
cord-278081-tk7vn1v1	380	94	and	and	CC
cord-278081-tk7vn1v1	380	95	function	function	VB
cord-278081-tk7vn1v1	380	96	The	the	DT
cord-278081-tk7vn1v1	380	97	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	380	98	under	under	IN
cord-278081-tk7vn1v1	380	99	stress	stress	NN
cord-278081-tk7vn1v1	381	1	The	the	DT
cord-278081-tk7vn1v1	381	2	multifunctional	multifunctional	JJ
cord-278081-tk7vn1v1	381	3	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	381	4	NOPdb	NOPdb	NNP
cord-278081-tk7vn1v1	381	5	:	:	:
cord-278081-tk7vn1v1	382	1	nucleolar	nucleolar	NNP
cord-278081-tk7vn1v1	382	2	proteome	proteome	NNP
cord-278081-tk7vn1v1	382	3	database-2008	database-2008	NNP
cord-278081-tk7vn1v1	382	4	update	update	NN
cord-278081-tk7vn1v1	382	5	Role	role	NN
cord-278081-tk7vn1v1	382	6	of	of	IN
cord-278081-tk7vn1v1	382	7	polyamine	polyamine	NN
cord-278081-tk7vn1v1	382	8	in	in	IN
cord-278081-tk7vn1v1	382	9	the	the	DT
cord-278081-tk7vn1v1	382	10	regulation	regulation	NN
cord-278081-tk7vn1v1	382	11	of	of	IN
cord-278081-tk7vn1v1	382	12	RNA	RNA	NNP
cord-278081-tk7vn1v1	382	13	synthesis	synthesis	NN
cord-278081-tk7vn1v1	382	14	in	in	IN
cord-278081-tk7vn1v1	382	15	uterine	uterine	JJ
cord-278081-tk7vn1v1	382	16	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	382	17	Assembly	Assembly	NNP
cord-278081-tk7vn1v1	382	18	and	and	CC
cord-278081-tk7vn1v1	382	19	disassembly	disassembly	NN
cord-278081-tk7vn1v1	382	20	of	of	IN
cord-278081-tk7vn1v1	382	21	the	the	DT
cord-278081-tk7vn1v1	382	22	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	382	23	during	during	IN
cord-278081-tk7vn1v1	382	24	the	the	DT
cord-278081-tk7vn1v1	382	25	cell	cell	NN
cord-278081-tk7vn1v1	382	26	cycle	cycle	NN
cord-278081-tk7vn1v1	382	27	Structure	Structure	NNP
cord-278081-tk7vn1v1	382	28	of	of	IN
cord-278081-tk7vn1v1	382	29	the	the	DT
cord-278081-tk7vn1v1	382	30	p53	p53	NN
cord-278081-tk7vn1v1	382	31	binding	bind	VBG
cord-278081-tk7vn1v1	382	32	domain	domain	NN
cord-278081-tk7vn1v1	382	33	of	of	IN
cord-278081-tk7vn1v1	382	34	HAUSP	HAUSP	NNP
cord-278081-tk7vn1v1	382	35	/	/	SYM
cord-278081-tk7vn1v1	382	36	USP7	USP7	NNP
cord-278081-tk7vn1v1	382	37	bound	bind	VBN
cord-278081-tk7vn1v1	382	38	to	to	IN
cord-278081-tk7vn1v1	382	39	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	382	40	-	-	HYPH
cord-278081-tk7vn1v1	382	41	Barr	Barr	NNP
cord-278081-tk7vn1v1	382	42	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	382	43	antigen	antigen	NN
cord-278081-tk7vn1v1	382	44	1	1	CD
cord-278081-tk7vn1v1	382	45	implications	implication	NNS
cord-278081-tk7vn1v1	382	46	for	for	IN
cord-278081-tk7vn1v1	382	47	EBV	EBV	NNP
cord-278081-tk7vn1v1	382	48	-	-	HYPH
cord-278081-tk7vn1v1	382	49	mediated	mediate	VBN
cord-278081-tk7vn1v1	382	50	immortalization	immortalization	NN
cord-278081-tk7vn1v1	382	51	Expression	expression	NN
cord-278081-tk7vn1v1	382	52	and	and	CC
cord-278081-tk7vn1v1	382	53	processing	processing	NN
cord-278081-tk7vn1v1	382	54	of	of	IN
cord-278081-tk7vn1v1	382	55	a	a	DT
cord-278081-tk7vn1v1	382	56	small	small	JJ
cord-278081-tk7vn1v1	382	57	nucleolar	nucleolar	NNS
cord-278081-tk7vn1v1	382	58	RNA	RNA	NNP
cord-278081-tk7vn1v1	382	59	from	from	IN
cord-278081-tk7vn1v1	382	60	the	the	DT
cord-278081-tk7vn1v1	382	61	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	382	62	-	-	HYPH
cord-278081-tk7vn1v1	382	63	Barr	Barr	NNP
cord-278081-tk7vn1v1	382	64	virus	virus	NN
cord-278081-tk7vn1v1	382	65	genome	genome	NN
cord-278081-tk7vn1v1	383	1	The	the	DT
cord-278081-tk7vn1v1	383	2	proto	proto	JJ
cord-278081-tk7vn1v1	383	3	-	-	HYPH
cord-278081-tk7vn1v1	383	4	oncogene	oncogene	NN
cord-278081-tk7vn1v1	383	5	c	c	NN
cord-278081-tk7vn1v1	383	6	-	-	HYPH
cord-278081-tk7vn1v1	383	7	myc	myc	NNP
cord-278081-tk7vn1v1	383	8	is	be	VBZ
cord-278081-tk7vn1v1	383	9	a	a	DT
cord-278081-tk7vn1v1	383	10	direct	direct	JJ
cord-278081-tk7vn1v1	383	11	target	target	NN
cord-278081-tk7vn1v1	383	12	of	of	IN
cord-278081-tk7vn1v1	383	13	gene	gene	NN
cord-278081-tk7vn1v1	383	14	of	of	IN
cord-278081-tk7vn1v1	383	15	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	383	16	-	-	HYPH
cord-278081-tk7vn1v1	383	17	Barr	Barr	NNP
cord-278081-tk7vn1v1	383	18	virus	virus	NN
cord-278081-tk7vn1v1	383	19	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	383	20	antigen	antigen	NN
cord-278081-tk7vn1v1	383	21	2	2	CD
cord-278081-tk7vn1v1	383	22	Epstein	Epstein	NNP
cord-278081-tk7vn1v1	383	23	-	-	HYPH
cord-278081-tk7vn1v1	383	24	Barr	Barr	NNP
cord-278081-tk7vn1v1	383	25	virus	virus	NN
cord-278081-tk7vn1v1	383	26	induces	induce	VBZ
cord-278081-tk7vn1v1	383	27	cellular	cellular	JJ
cord-278081-tk7vn1v1	383	28	transcription	transcription	NN
cord-278081-tk7vn1v1	383	29	factors	factor	NNS
cord-278081-tk7vn1v1	383	30	to	to	TO
cord-278081-tk7vn1v1	383	31	allow	allow	VB
cord-278081-tk7vn1v1	383	32	active	active	JJ
cord-278081-tk7vn1v1	383	33	expression	expression	NN
cord-278081-tk7vn1v1	383	34	of	of	IN
cord-278081-tk7vn1v1	383	35	EBER	EBER	NNP
cord-278081-tk7vn1v1	383	36	genes	gene	NNS
cord-278081-tk7vn1v1	383	37	by	by	IN
cord-278081-tk7vn1v1	383	38	RNA	RNA	NNP
cord-278081-tk7vn1v1	383	39	polymerase	polymerase	NN
cord-278081-tk7vn1v1	383	40	III	iii	CD
cord-278081-tk7vn1v1	383	41	Direct	direct	JJ
cord-278081-tk7vn1v1	383	42	activation	activation	NN
cord-278081-tk7vn1v1	383	43	of	of	IN
cord-278081-tk7vn1v1	383	44	RNA	RNA	NNP
cord-278081-tk7vn1v1	383	45	polymerase	polymerase	NN
cord-278081-tk7vn1v1	383	46	III	iii	CD
cord-278081-tk7vn1v1	383	47	transcription	transcription	NN
cord-278081-tk7vn1v1	383	48	by	by	IN
cord-278081-tk7vn1v1	383	49	c	c	NNP
cord-278081-tk7vn1v1	383	50	-	-	HYPH
cord-278081-tk7vn1v1	383	51	Myc	Myc	NNP
cord-278081-tk7vn1v1	383	52	c	c	NNP
cord-278081-tk7vn1v1	383	53	-	-	:
cord-278081-tk7vn1v1	383	54	Myc	Myc	NNP
cord-278081-tk7vn1v1	383	55	binds	bind	VBZ
cord-278081-tk7vn1v1	383	56	to	to	IN
cord-278081-tk7vn1v1	383	57	human	human	JJ
cord-278081-tk7vn1v1	383	58	ribosomal	ribosomal	JJ
cord-278081-tk7vn1v1	383	59	DNA	dna	NN
cord-278081-tk7vn1v1	383	60	and	and	CC
cord-278081-tk7vn1v1	383	61	stimulates	stimulate	VBZ
cord-278081-tk7vn1v1	383	62	transcription	transcription	NN
cord-278081-tk7vn1v1	383	63	of	of	IN
cord-278081-tk7vn1v1	383	64	rRNA	rrna	JJ
cord-278081-tk7vn1v1	383	65	genes	gene	NNS
cord-278081-tk7vn1v1	383	66	by	by	IN
cord-278081-tk7vn1v1	383	67	RNA	RNA	NNP
cord-278081-tk7vn1v1	383	68	polymerase	polymerase	NN
cord-278081-tk7vn1v1	383	69	I	-PRON-	PRP
cord-278081-tk7vn1v1	384	1	An	an	DT
cord-278081-tk7vn1v1	384	2	overview	overview	NN
cord-278081-tk7vn1v1	384	3	of	of	IN
cord-278081-tk7vn1v1	384	4	MYC	MYC	NNP
cord-278081-tk7vn1v1	384	5	and	and	CC
cord-278081-tk7vn1v1	384	6	its	-PRON-	PRP$
cord-278081-tk7vn1v1	384	7	interactome	interactome	NNP
cord-278081-tk7vn1v1	384	8	Autoimmune	Autoimmune	NNP
cord-278081-tk7vn1v1	384	9	diseases	disease	NNS
cord-278081-tk7vn1v1	384	10	and	and	CC
cord-278081-tk7vn1v1	384	11	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	385	1	The	the	DT
cord-278081-tk7vn1v1	385	2	ornithine	ornithine	NN
cord-278081-tk7vn1v1	385	3	decarboxylase	decarboxylase	NN
cord-278081-tk7vn1v1	385	4	gene	gene	NN
cord-278081-tk7vn1v1	385	5	is	be	VBZ
cord-278081-tk7vn1v1	385	6	a	a	DT
cord-278081-tk7vn1v1	385	7	transcriptional	transcriptional	JJ
cord-278081-tk7vn1v1	385	8	target	target	NN
cord-278081-tk7vn1v1	385	9	of	of	IN
cord-278081-tk7vn1v1	385	10	c	c	NN
cord-278081-tk7vn1v1	385	11	-	-	HYPH
cord-278081-tk7vn1v1	385	12	Myc	Myc	NNP
cord-278081-tk7vn1v1	385	13	c	c	NNP
cord-278081-tk7vn1v1	385	14	-	-	:
cord-278081-tk7vn1v1	385	15	Myc	Myc	NNP
cord-278081-tk7vn1v1	385	16	targets	target	NNS
cord-278081-tk7vn1v1	385	17	genes	gene	NNS
cord-278081-tk7vn1v1	385	18	involved	involve	VBN
cord-278081-tk7vn1v1	385	19	in	in	IN
cord-278081-tk7vn1v1	385	20	cell	cell	NN
cord-278081-tk7vn1v1	385	21	growth	growth	NN
cord-278081-tk7vn1v1	385	22	,	,	,
cord-278081-tk7vn1v1	385	23	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	385	24	,	,	,
cord-278081-tk7vn1v1	385	25	and	and	CC
cord-278081-tk7vn1v1	385	26	metabolism	metabolism	NN
cord-278081-tk7vn1v1	386	1	Targeting	target	VBG
cord-278081-tk7vn1v1	386	2	ornithine	ornithine	NN
cord-278081-tk7vn1v1	386	3	decarboxylase	decarboxylase	NN
cord-278081-tk7vn1v1	386	4	in	in	IN
cord-278081-tk7vn1v1	386	5	Myc	Myc	NNP
cord-278081-tk7vn1v1	386	6	-	-	HYPH
cord-278081-tk7vn1v1	386	7	induced	induce	VBN
cord-278081-tk7vn1v1	386	8	lymphomagenesis	lymphomagenesis	NN
cord-278081-tk7vn1v1	386	9	prevents	prevent	VBZ
cord-278081-tk7vn1v1	387	1	tumor	tumor	NN
cord-278081-tk7vn1v1	387	2	formation	formation	NN
cord-278081-tk7vn1v1	387	3	Ultrastructural	Ultrastructural	NNP
cord-278081-tk7vn1v1	387	4	changes	change	VBZ
cord-278081-tk7vn1v1	387	5	in	in	IN
cord-278081-tk7vn1v1	387	6	vitro	vitro	FW
cord-278081-tk7vn1v1	387	7	of	of	IN
cord-278081-tk7vn1v1	387	8	rat	rat	NNP
cord-278081-tk7vn1v1	387	9	liver	liver	NNP
cord-278081-tk7vn1v1	387	10	nucleoli	nucleoli	NNP
cord-278081-tk7vn1v1	387	11	in	in	IN
cord-278081-tk7vn1v1	387	12	response	response	NN
cord-278081-tk7vn1v1	387	13	to	to	IN
cord-278081-tk7vn1v1	387	14	polyamines	polyamines	NNP
cord-278081-tk7vn1v1	387	15	Relationship	relationship	NN
cord-278081-tk7vn1v1	387	16	between	between	IN
cord-278081-tk7vn1v1	387	17	polyamine	polyamine	NN
cord-278081-tk7vn1v1	387	18	accumulation	accumulation	NN
cord-278081-tk7vn1v1	387	19	and	and	CC
cord-278081-tk7vn1v1	387	20	RNA	RNA	NNP
cord-278081-tk7vn1v1	387	21	biosynthesis	biosynthesis	NN
cord-278081-tk7vn1v1	387	22	and	and	CC
cord-278081-tk7vn1v1	387	23	content	content	NN
cord-278081-tk7vn1v1	387	24	during	during	IN
cord-278081-tk7vn1v1	387	25	the	the	DT
cord-278081-tk7vn1v1	387	26	cell	cell	NN
cord-278081-tk7vn1v1	387	27	cycle	cycle	NN
cord-278081-tk7vn1v1	387	28	RNA	RNA	NNP
cord-278081-tk7vn1v1	387	29	viruses	virus	NNS
cord-278081-tk7vn1v1	387	30	:	:	:
cord-278081-tk7vn1v1	388	1	hijacking	hijack	VBG
cord-278081-tk7vn1v1	388	2	the	the	DT
cord-278081-tk7vn1v1	388	3	dynamic	dynamic	JJ
cord-278081-tk7vn1v1	388	4	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	388	5	Modifications	modification	NNS
cord-278081-tk7vn1v1	388	6	of	of	IN
cord-278081-tk7vn1v1	388	7	both	both	DT
cord-278081-tk7vn1v1	388	8	selectivity	selectivity	NN
cord-278081-tk7vn1v1	388	9	factor	factor	NN
cord-278081-tk7vn1v1	388	10	and	and	CC
cord-278081-tk7vn1v1	388	11	upstream	upstream	JJ
cord-278081-tk7vn1v1	388	12	binding	binding	NN
cord-278081-tk7vn1v1	388	13	factor	factor	NN
cord-278081-tk7vn1v1	388	14	contribute	contribute	VBP
cord-278081-tk7vn1v1	388	15	to	to	IN
cord-278081-tk7vn1v1	388	16	poliovirus	poliovirus	NN
cord-278081-tk7vn1v1	388	17	-	-	HYPH
cord-278081-tk7vn1v1	388	18	mediated	mediate	VBN
cord-278081-tk7vn1v1	388	19	inhibition	inhibition	NN
cord-278081-tk7vn1v1	388	20	of	of	IN
cord-278081-tk7vn1v1	388	21	RNA	RNA	NNP
cord-278081-tk7vn1v1	388	22	polymerase	polymerase	NN
cord-278081-tk7vn1v1	388	23	I	-PRON-	PRP
cord-278081-tk7vn1v1	388	24	transcription	transcription	VBP
cord-278081-tk7vn1v1	388	25	Viruses	virus	NNS
cord-278081-tk7vn1v1	388	26	and	and	CC
cord-278081-tk7vn1v1	388	27	the	the	DT
cord-278081-tk7vn1v1	388	28	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	388	29	:	:	:
cord-278081-tk7vn1v1	388	30	the	the	DT
cord-278081-tk7vn1v1	388	31	fatal	fatal	JJ
cord-278081-tk7vn1v1	388	32	attraction	attraction	NN
cord-278081-tk7vn1v1	388	33	Virus	Virus	NNP
cord-278081-tk7vn1v1	388	34	infection	infection	NN
cord-278081-tk7vn1v1	388	35	induces	induce	VBZ
cord-278081-tk7vn1v1	388	36	redistribution	redistribution	NN
cord-278081-tk7vn1v1	388	37	and	and	CC
cord-278081-tk7vn1v1	388	38	membrane	membrane	NN
cord-278081-tk7vn1v1	388	39	localization	localization	NN
cord-278081-tk7vn1v1	388	40	of	of	IN
cord-278081-tk7vn1v1	388	41	the	the	DT
cord-278081-tk7vn1v1	388	42	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	388	43	antigen	antigen	NN
cord-278081-tk7vn1v1	388	44	La	La	NNP
cord-278081-tk7vn1v1	388	45	(	(	-LRB-
cord-278081-tk7vn1v1	388	46	SS	SS	NNP
cord-278081-tk7vn1v1	388	47	-	-	HYPH
cord-278081-tk7vn1v1	388	48	B	B	NNP
cord-278081-tk7vn1v1	388	49	)	)	-RRB-
cord-278081-tk7vn1v1	388	50	:	:	:
cord-278081-tk7vn1v1	389	1	a	a	DT
cord-278081-tk7vn1v1	389	2	possible	possible	JJ
cord-278081-tk7vn1v1	389	3	mechanism	mechanism	NN
cord-278081-tk7vn1v1	389	4	for	for	IN
cord-278081-tk7vn1v1	389	5	autoimmunity	autoimmunity	NN
cord-278081-tk7vn1v1	389	6	X	x	NN
cord-278081-tk7vn1v1	389	7	chromosome	chromosome	NN
cord-278081-tk7vn1v1	389	8	inactivation	inactivation	NN
cord-278081-tk7vn1v1	389	9	and	and	CC
cord-278081-tk7vn1v1	389	10	autoimmunity	autoimmunity	IN
cord-278081-tk7vn1v1	389	11	Nucleolin	Nucleolin	NNP
cord-278081-tk7vn1v1	389	12	:	:	:
cord-278081-tk7vn1v1	390	1	the	the	DT
cord-278081-tk7vn1v1	390	2	most	most	RBS
cord-278081-tk7vn1v1	390	3	abundant	abundant	JJ
cord-278081-tk7vn1v1	390	4	multifunctional	multifunctional	JJ
cord-278081-tk7vn1v1	390	5	phosphoprotein	phosphoprotein	NN
cord-278081-tk7vn1v1	390	6	of	of	IN
cord-278081-tk7vn1v1	390	7	nucleolus	nucleolus	NN
cord-278081-tk7vn1v1	390	8	Nucleophosmin	Nucleophosmin	NNP
cord-278081-tk7vn1v1	390	9	:	:	:
cord-278081-tk7vn1v1	390	10	from	from	IN
cord-278081-tk7vn1v1	390	11	structure	structure	NN
cord-278081-tk7vn1v1	390	12	and	and	CC
cord-278081-tk7vn1v1	390	13	function	function	NN
cord-278081-tk7vn1v1	390	14	to	to	IN
cord-278081-tk7vn1v1	390	15	disease	disease	NN
cord-278081-tk7vn1v1	390	16	development	development	NN
cord-278081-tk7vn1v1	390	17	Increased	increase	VBN
cord-278081-tk7vn1v1	390	18	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	390	19	alter	alter	VBP
cord-278081-tk7vn1v1	390	20	chromatin	chromatin	NN
cord-278081-tk7vn1v1	390	21	and	and	CC
cord-278081-tk7vn1v1	390	22	stabilize	stabilize	VB
cord-278081-tk7vn1v1	390	23	autoantigens	autoantigen	NNS
cord-278081-tk7vn1v1	390	24	in	in	IN
cord-278081-tk7vn1v1	390	25	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	390	26	diseases	disease	NNS
cord-278081-tk7vn1v1	391	1	Noncoding	noncoding	JJ
cord-278081-tk7vn1v1	391	2	RNAs	rna	NNS
cord-278081-tk7vn1v1	391	3	and	and	CC
cord-278081-tk7vn1v1	391	4	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	391	5	mechanisms	mechanism	NNS
cord-278081-tk7vn1v1	391	6	during	during	IN
cord-278081-tk7vn1v1	391	7	X	x	NN
cord-278081-tk7vn1v1	391	8	-	-	NN
cord-278081-tk7vn1v1	391	9	chromosome	chromosome	NN
cord-278081-tk7vn1v1	391	10	inactivation	inactivation	NN
cord-278081-tk7vn1v1	391	11	X	x	NN
cord-278081-tk7vn1v1	391	12	-	-	NN
cord-278081-tk7vn1v1	391	13	inactivation	inactivation	NN
cord-278081-tk7vn1v1	391	14	profile	profile	NN
cord-278081-tk7vn1v1	391	15	reveals	reveal	VBZ
cord-278081-tk7vn1v1	391	16	extensive	extensive	JJ
cord-278081-tk7vn1v1	391	17	variability	variability	NN
cord-278081-tk7vn1v1	391	18	in	in	IN
cord-278081-tk7vn1v1	391	19	X	x	NN
cord-278081-tk7vn1v1	391	20	-	-	HYPH
cord-278081-tk7vn1v1	391	21	linked	link	VBN
cord-278081-tk7vn1v1	391	22	gene	gene	NN
cord-278081-tk7vn1v1	391	23	expression	expression	NN
cord-278081-tk7vn1v1	391	24	in	in	IN
cord-278081-tk7vn1v1	391	25	females	female	NNS
cord-278081-tk7vn1v1	391	26	Intense	intense	JJ
cord-278081-tk7vn1v1	391	27	correlation	correlation	NN
cord-278081-tk7vn1v1	391	28	between	between	IN
cord-278081-tk7vn1v1	391	29	protein	protein	NN
cord-278081-tk7vn1v1	391	30	-	-	HYPH
cord-278081-tk7vn1v1	391	31	conjugated	conjugate	VBN
cord-278081-tk7vn1v1	391	32	acrolein	acrolein	NN
cord-278081-tk7vn1v1	391	33	and	and	CC
cord-278081-tk7vn1v1	391	34	primary	primary	JJ
cord-278081-tk7vn1v1	391	35	Sjogren	Sjogren	NNP
cord-278081-tk7vn1v1	391	36	's	's	POS
cord-278081-tk7vn1v1	391	37	syndrome	syndrome	NN
cord-278081-tk7vn1v1	391	38	Recent	recent	JJ
cord-278081-tk7vn1v1	391	39	insights	insight	NNS
cord-278081-tk7vn1v1	391	40	into	into	IN
cord-278081-tk7vn1v1	391	41	the	the	DT
cord-278081-tk7vn1v1	391	42	regulation	regulation	NN
cord-278081-tk7vn1v1	391	43	of	of	IN
cord-278081-tk7vn1v1	391	44	X	x	NN
cord-278081-tk7vn1v1	391	45	-	-	NN
cord-278081-tk7vn1v1	391	46	chromosome	chromosome	NN
cord-278081-tk7vn1v1	391	47	inactivation	inactivation	NN
cord-278081-tk7vn1v1	391	48	LINE	line	NN
cord-278081-tk7vn1v1	391	49	-	-	HYPH
cord-278081-tk7vn1v1	391	50	mediated	mediate	VBN
cord-278081-tk7vn1v1	391	51	retrotransposition	retrotransposition	NN
cord-278081-tk7vn1v1	391	52	of	of	IN
cord-278081-tk7vn1v1	391	53	marked	mark	VBN
cord-278081-tk7vn1v1	391	54	Alu	Alu	NNP
cord-278081-tk7vn1v1	391	55	sequences	sequence	NNS
cord-278081-tk7vn1v1	391	56	Plasma	plasma	NN
cord-278081-tk7vn1v1	391	57	DNA	DNA	NNP
cord-278081-tk7vn1v1	391	58	in	in	IN
cord-278081-tk7vn1v1	391	59	systemic	systemic	JJ
cord-278081-tk7vn1v1	391	60	lupus	lupus	NN
cord-278081-tk7vn1v1	391	61	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	391	62	Post	post	JJ
cord-278081-tk7vn1v1	391	63	-	-	JJ
cord-278081-tk7vn1v1	391	64	translational	translational	JJ
cord-278081-tk7vn1v1	391	65	modifications	modification	NNS
cord-278081-tk7vn1v1	391	66	,	,	,
cord-278081-tk7vn1v1	391	67	subcellular	subcellular	JJ
cord-278081-tk7vn1v1	391	68	relocation	relocation	NN
cord-278081-tk7vn1v1	391	69	and	and	CC
cord-278081-tk7vn1v1	391	70	release	release	NN
cord-278081-tk7vn1v1	391	71	in	in	IN
cord-278081-tk7vn1v1	391	72	apoptotic	apoptotic	JJ
cord-278081-tk7vn1v1	391	73	microparticles	microparticle	NNS
cord-278081-tk7vn1v1	391	74	:	:	:
cord-278081-tk7vn1v1	392	1	apoptosis	apoptosis	NN
cord-278081-tk7vn1v1	392	2	turns	turn	VBZ
cord-278081-tk7vn1v1	392	3	nuclear	nuclear	JJ
cord-278081-tk7vn1v1	392	4	proteins	protein	NNS
cord-278081-tk7vn1v1	392	5	into	into	IN
cord-278081-tk7vn1v1	392	6	autoantigens	autoantigens	JJ
cord-278081-tk7vn1v1	392	7	cGAS	cgas	JJ
cord-278081-tk7vn1v1	392	8	surveillance	surveillance	NN
cord-278081-tk7vn1v1	392	9	of	of	IN
cord-278081-tk7vn1v1	392	10	micronuclei	micronuclei	NNP
cord-278081-tk7vn1v1	392	11	links	link	NNS
cord-278081-tk7vn1v1	392	12	genome	genome	NN
cord-278081-tk7vn1v1	392	13	instability	instability	NN
cord-278081-tk7vn1v1	392	14	to	to	IN
cord-278081-tk7vn1v1	392	15	innate	innate	JJ
cord-278081-tk7vn1v1	392	16	immunity	immunity	NN
cord-278081-tk7vn1v1	392	17	STING	sting	NN
cord-278081-tk7vn1v1	392	18	:	:	:
cord-278081-tk7vn1v1	392	19	infection	infection	NN
cord-278081-tk7vn1v1	392	20	,	,	,
cord-278081-tk7vn1v1	392	21	inflammation	inflammation	NN
cord-278081-tk7vn1v1	392	22	and	and	CC
cord-278081-tk7vn1v1	392	23	cancer	cancer	NN
cord-278081-tk7vn1v1	392	24	Autoantibodies	Autoantibodies	NNP
cord-278081-tk7vn1v1	392	25	in	in	IN
cord-278081-tk7vn1v1	392	26	patients	patient	NNS
cord-278081-tk7vn1v1	392	27	with	with	IN
cord-278081-tk7vn1v1	392	28	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	392	29	's	's	POS
cord-278081-tk7vn1v1	392	30	disease	disease	NN
cord-278081-tk7vn1v1	392	31	:	:	:
cord-278081-tk7vn1v1	392	32	pathogenetic	pathogenetic	JJ
cord-278081-tk7vn1v1	392	33	role	role	NN
cord-278081-tk7vn1v1	392	34	and	and	CC
cord-278081-tk7vn1v1	392	35	potential	potential	JJ
cord-278081-tk7vn1v1	392	36	use	use	NN
cord-278081-tk7vn1v1	392	37	as	as	IN
cord-278081-tk7vn1v1	392	38	biomarkers	biomarker	NNS
cord-278081-tk7vn1v1	392	39	of	of	IN
cord-278081-tk7vn1v1	392	40	disease	disease	NN
cord-278081-tk7vn1v1	392	41	progression	progression	NN
cord-278081-tk7vn1v1	392	42	Brain	Brain	NNP
cord-278081-tk7vn1v1	392	43	polyamine	polyamine	NN
cord-278081-tk7vn1v1	392	44	levels	level	NNS
cord-278081-tk7vn1v1	392	45	are	be	VBP
cord-278081-tk7vn1v1	392	46	altered	alter	VBN
cord-278081-tk7vn1v1	392	47	in	in	IN
cord-278081-tk7vn1v1	392	48	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	392	49	's	's	POS
cord-278081-tk7vn1v1	392	50	disease	disease	NN
cord-278081-tk7vn1v1	392	51	Polyamines	Polyamines	NNP
cord-278081-tk7vn1v1	392	52	in	in	IN
cord-278081-tk7vn1v1	392	53	frontal	frontal	JJ
cord-278081-tk7vn1v1	392	54	cortex	cortex	NN
cord-278081-tk7vn1v1	392	55	of	of	IN
cord-278081-tk7vn1v1	392	56	patients	patient	NNS
cord-278081-tk7vn1v1	392	57	with	with	IN
cord-278081-tk7vn1v1	392	58	Downs	Downs	NNP
cord-278081-tk7vn1v1	392	59	syndrome	syndrome	NN
cord-278081-tk7vn1v1	392	60	and	and	CC
cord-278081-tk7vn1v1	392	61	Frontiers	Frontiers	NNPS
cord-278081-tk7vn1v1	392	62	in	in	IN
cord-278081-tk7vn1v1	392	63	Immunology	Immunology	NNP
cord-278081-tk7vn1v1	392	64	|	|	NNP
cord-278081-tk7vn1v1	392	65	www	www	NNP
cord-278081-tk7vn1v1	392	66	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	392	67	disease	disease	NN
cord-278081-tk7vn1v1	393	1	Acrolein	acrolein	NN
cord-278081-tk7vn1v1	393	2	is	be	VBZ
cord-278081-tk7vn1v1	393	3	increased	increase	VBN
cord-278081-tk7vn1v1	393	4	in	in	IN
cord-278081-tk7vn1v1	393	5	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	393	6	's	's	POS
cord-278081-tk7vn1v1	393	7	disease	disease	NN
cord-278081-tk7vn1v1	393	8	brain	brain	NN
cord-278081-tk7vn1v1	393	9	and	and	CC
cord-278081-tk7vn1v1	393	10	is	be	VBZ
cord-278081-tk7vn1v1	393	11	toxic	toxic	JJ
cord-278081-tk7vn1v1	393	12	to	to	IN
cord-278081-tk7vn1v1	393	13	primary	primary	JJ
cord-278081-tk7vn1v1	393	14	hippocampal	hippocampal	JJ
cord-278081-tk7vn1v1	393	15	cultures	culture	NNS
cord-278081-tk7vn1v1	394	1	Brain	Brain	NNP
cord-278081-tk7vn1v1	394	2	S	S	NNP
cord-278081-tk7vn1v1	394	3	-	-	HYPH
cord-278081-tk7vn1v1	394	4	adenosylmethionine	adenosylmethionine	NN
cord-278081-tk7vn1v1	394	5	levels	level	NNS
cord-278081-tk7vn1v1	394	6	are	be	VBP
cord-278081-tk7vn1v1	394	7	severely	severely	RB
cord-278081-tk7vn1v1	394	8	decreased	decrease	VBN
cord-278081-tk7vn1v1	394	9	in	in	IN
cord-278081-tk7vn1v1	394	10	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	394	11	's	's	POS
cord-278081-tk7vn1v1	394	12	disease	disease	NN
cord-278081-tk7vn1v1	395	1	Endogenous	endogenous	JJ
cord-278081-tk7vn1v1	395	2	polyamines	polyamine	NNS
cord-278081-tk7vn1v1	395	3	reduce	reduce	VBP
cord-278081-tk7vn1v1	395	4	the	the	DT
cord-278081-tk7vn1v1	395	5	toxicity	toxicity	NN
cord-278081-tk7vn1v1	395	6	of	of	IN
cord-278081-tk7vn1v1	395	7	soluble	soluble	JJ
cord-278081-tk7vn1v1	395	8	Aβ	Aβ	NNP
cord-278081-tk7vn1v1	395	9	peptide	peptide	NN
cord-278081-tk7vn1v1	395	10	aggregates	aggregate	NNS
cord-278081-tk7vn1v1	395	11	associated	associate	VBN
cord-278081-tk7vn1v1	395	12	with	with	IN
cord-278081-tk7vn1v1	395	13	Alzheier	Alzheier	NNP
cord-278081-tk7vn1v1	395	14	's	's	POS
cord-278081-tk7vn1v1	395	15	disease	disease	NN
cord-278081-tk7vn1v1	396	1	Nucleolar	Nucleolar	NNP
cord-278081-tk7vn1v1	396	2	PARP1	PARP1	NNP
cord-278081-tk7vn1v1	396	3	expression	expression	NN
cord-278081-tk7vn1v1	396	4	is	be	VBZ
cord-278081-tk7vn1v1	396	5	decreased	decrease	VBN
cord-278081-tk7vn1v1	396	6	in	in	IN
cord-278081-tk7vn1v1	396	7	Alzheimer	Alzheimer	NNP
cord-278081-tk7vn1v1	396	8	's	's	POS
cord-278081-tk7vn1v1	396	9	disease	disease	NN
cord-278081-tk7vn1v1	396	10	:	:	:
cord-278081-tk7vn1v1	396	11	consequences	consequence	NNS
cord-278081-tk7vn1v1	396	12	for	for	IN
cord-278081-tk7vn1v1	396	13	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	396	14	regulation	regulation	NN
cord-278081-tk7vn1v1	396	15	of	of	IN
cord-278081-tk7vn1v1	396	16	rDNA	rdna	NN
cord-278081-tk7vn1v1	396	17	and	and	CC
cord-278081-tk7vn1v1	396	18	cognition	cognition	NN
cord-278081-tk7vn1v1	397	1	The	the	DT
cord-278081-tk7vn1v1	397	2	disappearing	disappear	VBG
cord-278081-tk7vn1v1	397	3	Barr	Barr	NNP
cord-278081-tk7vn1v1	397	4	body	body	NN
cord-278081-tk7vn1v1	397	5	in	in	IN
cord-278081-tk7vn1v1	397	6	breast	breast	NN
cord-278081-tk7vn1v1	397	7	and	and	CC
cord-278081-tk7vn1v1	397	8	ovarian	ovarian	JJ
cord-278081-tk7vn1v1	397	9	cancers	cancer	NNS
cord-278081-tk7vn1v1	398	1	Triple	triple	JJ
cord-278081-tk7vn1v1	398	2	-	-	HYPH
cord-278081-tk7vn1v1	398	3	negative	negative	JJ
cord-278081-tk7vn1v1	398	4	breast	breast	NN
cord-278081-tk7vn1v1	398	5	cancer	cancer	NN
cord-278081-tk7vn1v1	398	6	Epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	398	7	connections	connection	NNS
cord-278081-tk7vn1v1	398	8	between	between	IN
cord-278081-tk7vn1v1	398	9	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	398	10	disorders	disorder	NNS
cord-278081-tk7vn1v1	398	11	and	and	CC
cord-278081-tk7vn1v1	398	12	haematological	haematological	JJ
cord-278081-tk7vn1v1	398	13	malignancies	malignancy	NNS
cord-278081-tk7vn1v1	398	14	Cancer	Cancer	NNP
cord-278081-tk7vn1v1	398	15	risk	risk	NN
cord-278081-tk7vn1v1	398	16	in	in	IN
cord-278081-tk7vn1v1	398	17	systemic	systemic	JJ
cord-278081-tk7vn1v1	398	18	lupus	lupus	NN
cord-278081-tk7vn1v1	399	1	:	:	:
cord-278081-tk7vn1v1	399	2	an	an	DT
cord-278081-tk7vn1v1	399	3	updated	update	VBN
cord-278081-tk7vn1v1	399	4	international	international	JJ
cord-278081-tk7vn1v1	399	5	multi	multi	JJ
cord-278081-tk7vn1v1	399	6	-	-	JJ
cord-278081-tk7vn1v1	399	7	centre	centre	JJ
cord-278081-tk7vn1v1	399	8	cohort	cohort	NN
cord-278081-tk7vn1v1	399	9	study	study	NN
cord-278081-tk7vn1v1	399	10	Systemic	systemic	JJ
cord-278081-tk7vn1v1	399	11	lupus	lupus	NN
cord-278081-tk7vn1v1	399	12	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	399	13	and	and	CC
cord-278081-tk7vn1v1	399	14	related	related	JJ
cord-278081-tk7vn1v1	399	15	autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	399	16	diseases	disease	NNS
cord-278081-tk7vn1v1	399	17	are	be	VBP
cord-278081-tk7vn1v1	399	18	antigen	antigen	NN
cord-278081-tk7vn1v1	399	19	-	-	HYPH
cord-278081-tk7vn1v1	399	20	driven	drive	VBN
cord-278081-tk7vn1v1	399	21	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	399	22	diseases	disease	NNS
cord-278081-tk7vn1v1	399	23	Autoimmune	autoimmune	JJ
cord-278081-tk7vn1v1	399	24	disorders	disorder	NNS
cord-278081-tk7vn1v1	399	25	result	result	VBP
cord-278081-tk7vn1v1	399	26	from	from	IN
cord-278081-tk7vn1v1	399	27	loss	loss	NN
cord-278081-tk7vn1v1	399	28	of	of	IN
cord-278081-tk7vn1v1	399	29	epigenetic	epigenetic	JJ
cord-278081-tk7vn1v1	399	30	control	control	NN
cord-278081-tk7vn1v1	399	31	following	follow	VBG
cord-278081-tk7vn1v1	399	32	chromosome	chromosome	NN
cord-278081-tk7vn1v1	399	33	damage	damage	NN
cord-278081-tk7vn1v1	399	34	Rare	Rare	NNP
cord-278081-tk7vn1v1	399	35	X	x	NN
cord-278081-tk7vn1v1	399	36	chromosome	chromosome	NN
cord-278081-tk7vn1v1	399	37	abnormalities	abnormality	NNS
cord-278081-tk7vn1v1	399	38	in	in	IN
cord-278081-tk7vn1v1	399	39	systemic	systemic	JJ
cord-278081-tk7vn1v1	399	40	lupus	lupus	NN
cord-278081-tk7vn1v1	399	41	erythematosus	erythematosus	NN
cord-278081-tk7vn1v1	399	42	and	and	CC
cord-278081-tk7vn1v1	399	43	Sjögren	Sjögren	NNP
cord-278081-tk7vn1v1	399	44	's	's	POS
cord-278081-tk7vn1v1	399	45	syndrome	syndrome	NN