id	sid	tid	token	lemma	pos
cord-298458-p7rvupjo	1	1	key	key	JJ
cord-298458-p7rvupjo	1	2	:	:	:
cord-298458-p7rvupjo	1	3	cord-298458-p7rvupjo	cord-298458-p7rvupjo	JJ
cord-298458-p7rvupjo	1	4	authors	author	NNS
cord-298458-p7rvupjo	1	5	:	:	:
cord-298458-p7rvupjo	1	6	Schmidt	Schmidt	NNP
cord-298458-p7rvupjo	1	7	,	,	,
cord-298458-p7rvupjo	1	8	Megan	Megan	NNP
cord-298458-p7rvupjo	1	9	E.	E.	NNP
cord-298458-p7rvupjo	1	10	;	;	:
cord-298458-p7rvupjo	1	11	Varga	Varga	NNP
cord-298458-p7rvupjo	1	12	,	,	,
cord-298458-p7rvupjo	1	13	Steven	Steven	NNP
cord-298458-p7rvupjo	1	14	M.	M.	NNP
cord-298458-p7rvupjo	1	15	title	title	NN
cord-298458-p7rvupjo	1	16	:	:	:
cord-298458-p7rvupjo	1	17	The	the	DT
cord-298458-p7rvupjo	1	18	CD8	CD8	NNP
cord-298458-p7rvupjo	1	19	T	T	NNP
cord-298458-p7rvupjo	1	20	Cell	Cell	NNP
cord-298458-p7rvupjo	1	21	Response	response	NN
cord-298458-p7rvupjo	1	22	to	to	IN
cord-298458-p7rvupjo	1	23	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	1	24	Virus	Virus	NNP
cord-298458-p7rvupjo	1	25	Infections	Infections	NNP
cord-298458-p7rvupjo	1	26	date	date	NN
cord-298458-p7rvupjo	1	27	:	:	:
cord-298458-p7rvupjo	1	28	2018	2018	CD
cord-298458-p7rvupjo	1	29	-	-	HYPH
cord-298458-p7rvupjo	1	30	04	04	CD
cord-298458-p7rvupjo	1	31	-	-	HYPH
cord-298458-p7rvupjo	1	32	09	09	CD
cord-298458-p7rvupjo	1	33	journal	journal	NN
cord-298458-p7rvupjo	1	34	:	:	:
cord-298458-p7rvupjo	2	1	Front	Front	NNP
cord-298458-p7rvupjo	2	2	Immunol	Immunol	NNP
cord-298458-p7rvupjo	2	3	DOI	doi	NN
cord-298458-p7rvupjo	2	4	:	:	:
cord-298458-p7rvupjo	3	1	10.3389	10.3389	CD
cord-298458-p7rvupjo	3	2	/	/	SYM
cord-298458-p7rvupjo	3	3	fimmu.2018.00678	fimmu.2018.00678	CD
cord-298458-p7rvupjo	3	4	sha	sha	NNP
cord-298458-p7rvupjo	3	5	:	:	:
cord-298458-p7rvupjo	4	1	68d01d19a8c579cd8c528e8e24cd0720216ba700	68d01d19a8c579cd8c528e8e24cd0720216ba700	CD
cord-298458-p7rvupjo	4	2	doc_id	doc_id	CD
cord-298458-p7rvupjo	4	3	:	:	:
cord-298458-p7rvupjo	5	1	298458	298458	CD
cord-298458-p7rvupjo	5	2	cord_uid	cord_uid	NNS
cord-298458-p7rvupjo	5	3	:	:	:
cord-298458-p7rvupjo	6	1	p7rvupjo	p7rvupjo	NNP
cord-298458-p7rvupjo	6	2	Humans	human	NNS
cord-298458-p7rvupjo	6	3	are	be	VBP
cord-298458-p7rvupjo	6	4	highly	highly	RB
cord-298458-p7rvupjo	6	5	susceptible	susceptible	JJ
cord-298458-p7rvupjo	6	6	to	to	IN
cord-298458-p7rvupjo	6	7	infection	infection	NN
cord-298458-p7rvupjo	6	8	with	with	IN
cord-298458-p7rvupjo	6	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	6	10	viruses	virus	NNS
cord-298458-p7rvupjo	6	11	including	include	VBG
cord-298458-p7rvupjo	6	12	respiratory	respiratory	JJ
cord-298458-p7rvupjo	6	13	syncytial	syncytial	JJ
cord-298458-p7rvupjo	6	14	virus	virus	NN
cord-298458-p7rvupjo	6	15	(	(	-LRB-
cord-298458-p7rvupjo	6	16	RSV	RSV	NNP
cord-298458-p7rvupjo	6	17	)	)	-RRB-
cord-298458-p7rvupjo	6	18	,	,	,
cord-298458-p7rvupjo	6	19	influenza	influenza	NN
cord-298458-p7rvupjo	6	20	virus	virus	NN
cord-298458-p7rvupjo	6	21	,	,	,
cord-298458-p7rvupjo	6	22	human	human	JJ
cord-298458-p7rvupjo	6	23	metapneumovirus	metapneumovirus	NNP
cord-298458-p7rvupjo	6	24	,	,	,
cord-298458-p7rvupjo	6	25	rhinovirus	rhinovirus	NN
cord-298458-p7rvupjo	6	26	,	,	,
cord-298458-p7rvupjo	6	27	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	6	28	,	,	,
cord-298458-p7rvupjo	6	29	and	and	CC
cord-298458-p7rvupjo	6	30	parainfluenza	parainfluenza	NNP
cord-298458-p7rvupjo	6	31	virus	virus	NNP
cord-298458-p7rvupjo	6	32	.	.	.
cord-298458-p7rvupjo	7	1	While	while	IN
cord-298458-p7rvupjo	7	2	some	some	DT
cord-298458-p7rvupjo	7	3	viruses	virus	NNS
cord-298458-p7rvupjo	7	4	simply	simply	RB
cord-298458-p7rvupjo	7	5	cause	cause	VBP
cord-298458-p7rvupjo	7	6	symptoms	symptom	NNS
cord-298458-p7rvupjo	7	7	of	of	IN
cord-298458-p7rvupjo	7	8	the	the	DT
cord-298458-p7rvupjo	7	9	common	common	JJ
cord-298458-p7rvupjo	7	10	cold	cold	JJ
cord-298458-p7rvupjo	7	11	,	,	,
cord-298458-p7rvupjo	7	12	many	many	JJ
cord-298458-p7rvupjo	7	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	7	14	viruses	virus	NNS
cord-298458-p7rvupjo	7	15	induce	induce	VBP
cord-298458-p7rvupjo	7	16	severe	severe	JJ
cord-298458-p7rvupjo	7	17	bronchiolitis	bronchiolitis	NN
cord-298458-p7rvupjo	7	18	,	,	,
cord-298458-p7rvupjo	7	19	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	7	20	,	,	,
cord-298458-p7rvupjo	7	21	and	and	CC
cord-298458-p7rvupjo	7	22	even	even	RB
cord-298458-p7rvupjo	7	23	death	death	NN
cord-298458-p7rvupjo	7	24	following	follow	VBG
cord-298458-p7rvupjo	7	25	infection	infection	NN
cord-298458-p7rvupjo	7	26	.	.	.
cord-298458-p7rvupjo	8	1	Despite	despite	IN
cord-298458-p7rvupjo	8	2	the	the	DT
cord-298458-p7rvupjo	8	3	immense	immense	JJ
cord-298458-p7rvupjo	8	4	clinical	clinical	JJ
cord-298458-p7rvupjo	8	5	burden	burden	NN
cord-298458-p7rvupjo	8	6	,	,	,
cord-298458-p7rvupjo	8	7	the	the	DT
cord-298458-p7rvupjo	8	8	majority	majority	NN
cord-298458-p7rvupjo	8	9	of	of	IN
cord-298458-p7rvupjo	8	10	the	the	DT
cord-298458-p7rvupjo	8	11	most	most	RBS
cord-298458-p7rvupjo	8	12	common	common	JJ
cord-298458-p7rvupjo	8	13	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	8	14	viruses	virus	NNS
cord-298458-p7rvupjo	8	15	lack	lack	VBP
cord-298458-p7rvupjo	8	16	long	long	RB
cord-298458-p7rvupjo	8	17	-	-	HYPH
cord-298458-p7rvupjo	8	18	lasting	last	VBG
cord-298458-p7rvupjo	8	19	efficacious	efficacious	JJ
cord-298458-p7rvupjo	8	20	vaccines	vaccine	NNS
cord-298458-p7rvupjo	8	21	.	.	.
cord-298458-p7rvupjo	9	1	Nearly	nearly	RB
cord-298458-p7rvupjo	9	2	all	all	DT
cord-298458-p7rvupjo	9	3	current	current	JJ
cord-298458-p7rvupjo	9	4	vaccination	vaccination	NN
cord-298458-p7rvupjo	9	5	strategies	strategy	NNS
cord-298458-p7rvupjo	9	6	are	be	VBP
cord-298458-p7rvupjo	9	7	designed	design	VBN
cord-298458-p7rvupjo	9	8	to	to	TO
cord-298458-p7rvupjo	9	9	elicit	elicit	VB
cord-298458-p7rvupjo	9	10	broadly	broadly	RB
cord-298458-p7rvupjo	9	11	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	9	12	antibodies	antibody	NNS
cord-298458-p7rvupjo	9	13	,	,	,
cord-298458-p7rvupjo	9	14	which	which	WDT
cord-298458-p7rvupjo	9	15	prevent	prevent	VBP
cord-298458-p7rvupjo	9	16	severe	severe	JJ
cord-298458-p7rvupjo	9	17	disease	disease	NN
cord-298458-p7rvupjo	9	18	following	follow	VBG
cord-298458-p7rvupjo	9	19	a	a	DT
cord-298458-p7rvupjo	9	20	subsequent	subsequent	JJ
cord-298458-p7rvupjo	9	21	infection	infection	NN
cord-298458-p7rvupjo	9	22	.	.	.
cord-298458-p7rvupjo	10	1	However	however	RB
cord-298458-p7rvupjo	10	2	,	,	,
cord-298458-p7rvupjo	10	3	the	the	DT
cord-298458-p7rvupjo	10	4	mucosal	mucosal	JJ
cord-298458-p7rvupjo	10	5	antibody	antibody	NN
cord-298458-p7rvupjo	10	6	response	response	NN
cord-298458-p7rvupjo	10	7	to	to	IN
cord-298458-p7rvupjo	10	8	many	many	JJ
cord-298458-p7rvupjo	10	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	10	10	viruses	virus	NNS
cord-298458-p7rvupjo	10	11	is	be	VBZ
cord-298458-p7rvupjo	10	12	not	not	RB
cord-298458-p7rvupjo	10	13	long	long	RB
cord-298458-p7rvupjo	10	14	-	-	HYPH
cord-298458-p7rvupjo	10	15	lasting	last	VBG
cord-298458-p7rvupjo	10	16	and	and	CC
cord-298458-p7rvupjo	10	17	declines	decline	NNS
cord-298458-p7rvupjo	10	18	with	with	IN
cord-298458-p7rvupjo	10	19	age	age	NN
cord-298458-p7rvupjo	10	20	.	.	.
cord-298458-p7rvupjo	11	1	CD8	CD8	NNP
cord-298458-p7rvupjo	11	2	T	T	NNP
cord-298458-p7rvupjo	11	3	cells	cell	NNS
cord-298458-p7rvupjo	11	4	are	be	VBP
cord-298458-p7rvupjo	11	5	critical	critical	JJ
cord-298458-p7rvupjo	11	6	for	for	IN
cord-298458-p7rvupjo	11	7	mediating	mediate	VBG
cord-298458-p7rvupjo	11	8	clearance	clearance	NN
cord-298458-p7rvupjo	11	9	following	follow	VBG
cord-298458-p7rvupjo	11	10	many	many	JJ
cord-298458-p7rvupjo	11	11	acute	acute	JJ
cord-298458-p7rvupjo	11	12	viral	viral	JJ
cord-298458-p7rvupjo	11	13	infections	infection	NNS
cord-298458-p7rvupjo	11	14	in	in	IN
cord-298458-p7rvupjo	11	15	the	the	DT
cord-298458-p7rvupjo	11	16	lung	lung	NN
cord-298458-p7rvupjo	11	17	.	.	.
cord-298458-p7rvupjo	12	1	In	in	IN
cord-298458-p7rvupjo	12	2	addition	addition	NN
cord-298458-p7rvupjo	12	3	,	,	,
cord-298458-p7rvupjo	12	4	memory	memory	NN
cord-298458-p7rvupjo	12	5	CD8	CD8	NNP
cord-298458-p7rvupjo	12	6	T	T	NNP
cord-298458-p7rvupjo	12	7	cells	cell	NNS
cord-298458-p7rvupjo	12	8	are	be	VBP
cord-298458-p7rvupjo	12	9	capable	capable	JJ
cord-298458-p7rvupjo	12	10	of	of	IN
cord-298458-p7rvupjo	12	11	providing	provide	VBG
cord-298458-p7rvupjo	12	12	protection	protection	NN
cord-298458-p7rvupjo	12	13	against	against	IN
cord-298458-p7rvupjo	12	14	secondary	secondary	JJ
cord-298458-p7rvupjo	12	15	infections	infection	NNS
cord-298458-p7rvupjo	12	16	.	.	.
cord-298458-p7rvupjo	13	1	Therefore	therefore	RB
cord-298458-p7rvupjo	13	2	,	,	,
cord-298458-p7rvupjo	13	3	the	the	DT
cord-298458-p7rvupjo	13	4	combined	combine	VBN
cord-298458-p7rvupjo	13	5	induction	induction	NN
cord-298458-p7rvupjo	13	6	of	of	IN
cord-298458-p7rvupjo	13	7	virus	virus	NN
cord-298458-p7rvupjo	13	8	-	-	HYPH
cord-298458-p7rvupjo	13	9	specific	specific	JJ
cord-298458-p7rvupjo	13	10	CD8	CD8	NNP
cord-298458-p7rvupjo	13	11	T	T	NNP
cord-298458-p7rvupjo	13	12	cells	cell	NNS
cord-298458-p7rvupjo	13	13	and	and	CC
cord-298458-p7rvupjo	13	14	antibodies	antibody	NNS
cord-298458-p7rvupjo	13	15	may	may	MD
cord-298458-p7rvupjo	13	16	provide	provide	VB
cord-298458-p7rvupjo	13	17	optimal	optimal	JJ
cord-298458-p7rvupjo	13	18	protective	protective	JJ
cord-298458-p7rvupjo	13	19	immunity	immunity	NN
cord-298458-p7rvupjo	13	20	.	.	.
cord-298458-p7rvupjo	14	1	Herein	herein	RB
cord-298458-p7rvupjo	14	2	,	,	,
cord-298458-p7rvupjo	14	3	we	-PRON-	PRP
cord-298458-p7rvupjo	14	4	review	review	VBP
cord-298458-p7rvupjo	14	5	the	the	DT
cord-298458-p7rvupjo	14	6	current	current	JJ
cord-298458-p7rvupjo	14	7	literature	literature	NN
cord-298458-p7rvupjo	14	8	on	on	IN
cord-298458-p7rvupjo	14	9	CD8	CD8	NNP
cord-298458-p7rvupjo	14	10	T	T	NNP
cord-298458-p7rvupjo	14	11	cell	cell	NN
cord-298458-p7rvupjo	14	12	responses	response	NNS
cord-298458-p7rvupjo	14	13	induced	induce	VBN
cord-298458-p7rvupjo	14	14	by	by	IN
cord-298458-p7rvupjo	14	15	respiratory	respiratory	JJ
cord-298458-p7rvupjo	14	16	virus	virus	NN
cord-298458-p7rvupjo	14	17	infections	infection	NNS
cord-298458-p7rvupjo	14	18	.	.	.
cord-298458-p7rvupjo	15	1	Additionally	additionally	RB
cord-298458-p7rvupjo	15	2	,	,	,
cord-298458-p7rvupjo	15	3	we	-PRON-	PRP
cord-298458-p7rvupjo	15	4	explore	explore	VBP
cord-298458-p7rvupjo	15	5	how	how	WRB
cord-298458-p7rvupjo	15	6	this	this	DT
cord-298458-p7rvupjo	15	7	knowledge	knowledge	NN
cord-298458-p7rvupjo	15	8	could	could	MD
cord-298458-p7rvupjo	15	9	be	be	VB
cord-298458-p7rvupjo	15	10	utilized	utilize	VBN
cord-298458-p7rvupjo	15	11	in	in	IN
cord-298458-p7rvupjo	15	12	the	the	DT
cord-298458-p7rvupjo	15	13	development	development	NN
cord-298458-p7rvupjo	15	14	of	of	IN
cord-298458-p7rvupjo	15	15	future	future	JJ
cord-298458-p7rvupjo	15	16	vaccines	vaccine	NNS
cord-298458-p7rvupjo	15	17	against	against	IN
cord-298458-p7rvupjo	15	18	respiratory	respiratory	JJ
cord-298458-p7rvupjo	15	19	viruses	virus	NNS
cord-298458-p7rvupjo	15	20	,	,	,
cord-298458-p7rvupjo	15	21	with	with	IN
cord-298458-p7rvupjo	15	22	a	a	DT
cord-298458-p7rvupjo	15	23	special	special	JJ
cord-298458-p7rvupjo	15	24	emphasis	emphasis	NN
cord-298458-p7rvupjo	15	25	on	on	IN
cord-298458-p7rvupjo	15	26	RSV	RSV	NNP
cord-298458-p7rvupjo	15	27	vaccination	vaccination	NN
cord-298458-p7rvupjo	15	28	.	.	.
cord-298458-p7rvupjo	16	1	iNTRODUCTiON	iNTRODUCTiON	NNP
cord-298458-p7rvupjo	17	1	Given	give	VBN
cord-298458-p7rvupjo	17	2	its	-PRON-	PRP$
cord-298458-p7rvupjo	17	3	continuous	continuous	JJ
cord-298458-p7rvupjo	17	4	exposure	exposure	NN
cord-298458-p7rvupjo	17	5	to	to	IN
cord-298458-p7rvupjo	17	6	the	the	DT
cord-298458-p7rvupjo	17	7	outside	outside	JJ
cord-298458-p7rvupjo	17	8	environment	environment	NN
cord-298458-p7rvupjo	17	9	,	,	,
cord-298458-p7rvupjo	17	10	the	the	DT
cord-298458-p7rvupjo	17	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	17	12	mucosa	mucosa	NN
cord-298458-p7rvupjo	17	13	is	be	VBZ
cord-298458-p7rvupjo	17	14	highly	highly	RB
cord-298458-p7rvupjo	17	15	susceptible	susceptible	JJ
cord-298458-p7rvupjo	17	16	to	to	IN
cord-298458-p7rvupjo	17	17	viral	viral	JJ
cord-298458-p7rvupjo	17	18	infection	infection	NN
cord-298458-p7rvupjo	17	19	.	.	.
cord-298458-p7rvupjo	18	1	The	the	DT
cord-298458-p7rvupjo	18	2	human	human	JJ
cord-298458-p7rvupjo	18	3	respiratory	respiratory	JJ
cord-298458-p7rvupjo	18	4	tract	tract	NN
cord-298458-p7rvupjo	18	5	can	can	MD
cord-298458-p7rvupjo	18	6	be	be	VB
cord-298458-p7rvupjo	18	7	infected	infect	VBN
cord-298458-p7rvupjo	18	8	with	with	IN
cord-298458-p7rvupjo	18	9	a	a	DT
cord-298458-p7rvupjo	18	10	variety	variety	NN
cord-298458-p7rvupjo	18	11	of	of	IN
cord-298458-p7rvupjo	18	12	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	18	13	viruses	virus	NNS
cord-298458-p7rvupjo	18	14	,	,	,
cord-298458-p7rvupjo	18	15	including	include	VBG
cord-298458-p7rvupjo	18	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	18	17	syncytial	syncytial	JJ
cord-298458-p7rvupjo	18	18	virus	virus	NN
cord-298458-p7rvupjo	18	19	(	(	-LRB-
cord-298458-p7rvupjo	18	20	RSV	RSV	NNP
cord-298458-p7rvupjo	18	21	)	)	-RRB-
cord-298458-p7rvupjo	18	22	,	,	,
cord-298458-p7rvupjo	18	23	influenza	influenza	NN
cord-298458-p7rvupjo	18	24	virus	virus	NN
cord-298458-p7rvupjo	18	25	,	,	,
cord-298458-p7rvupjo	18	26	human	human	JJ
cord-298458-p7rvupjo	18	27	metapneumovirus	metapneumovirus	NNP
cord-298458-p7rvupjo	18	28	(	(	-LRB-
cord-298458-p7rvupjo	18	29	HMPV	HMPV	NNP
cord-298458-p7rvupjo	18	30	)	)	-RRB-
cord-298458-p7rvupjo	18	31	,	,	,
cord-298458-p7rvupjo	18	32	rhinovirus	rhinovirus	NN
cord-298458-p7rvupjo	18	33	(	(	-LRB-
cord-298458-p7rvupjo	18	34	RV	RV	NNP
cord-298458-p7rvupjo	18	35	)	)	-RRB-
cord-298458-p7rvupjo	18	36	,	,	,
cord-298458-p7rvupjo	18	37	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	18	38	(	(	-LRB-
cord-298458-p7rvupjo	18	39	CoV	CoV	NNP
cord-298458-p7rvupjo	18	40	)	)	-RRB-
cord-298458-p7rvupjo	18	41	,	,	,
cord-298458-p7rvupjo	18	42	and	and	CC
cord-298458-p7rvupjo	18	43	parainfluenza	parainfluenza	NNP
cord-298458-p7rvupjo	18	44	virus	virus	NNP
cord-298458-p7rvupjo	18	45	(	(	-LRB-
cord-298458-p7rvupjo	18	46	PIV	PIV	NNP
cord-298458-p7rvupjo	18	47	)	)	-RRB-
cord-298458-p7rvupjo	18	48	(	(	-LRB-
cord-298458-p7rvupjo	18	49	1	1	CD
cord-298458-p7rvupjo	18	50	)	)	-RRB-
cord-298458-p7rvupjo	18	51	.	.	.
cord-298458-p7rvupjo	19	1	The	the	DT
cord-298458-p7rvupjo	19	2	severity	severity	NN
cord-298458-p7rvupjo	19	3	of	of	IN
cord-298458-p7rvupjo	19	4	disease	disease	NN
cord-298458-p7rvupjo	19	5	associated	associate	VBN
cord-298458-p7rvupjo	19	6	with	with	IN
cord-298458-p7rvupjo	19	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	19	8	viral	viral	JJ
cord-298458-p7rvupjo	19	9	infection	infection	NN
cord-298458-p7rvupjo	19	10	varies	vary	VBZ
cord-298458-p7rvupjo	19	11	widely	widely	RB
cord-298458-p7rvupjo	19	12	depending	depend	VBG
cord-298458-p7rvupjo	19	13	on	on	IN
cord-298458-p7rvupjo	19	14	the	the	DT
cord-298458-p7rvupjo	19	15	virus	virus	NN
cord-298458-p7rvupjo	19	16	strain	strain	NN
cord-298458-p7rvupjo	19	17	as	as	RB
cord-298458-p7rvupjo	19	18	well	well	RB
cord-298458-p7rvupjo	19	19	as	as	IN
cord-298458-p7rvupjo	19	20	the	the	DT
cord-298458-p7rvupjo	19	21	age	age	NN
cord-298458-p7rvupjo	19	22	and	and	CC
cord-298458-p7rvupjo	19	23	immune	immune	JJ
cord-298458-p7rvupjo	19	24	status	status	NN
cord-298458-p7rvupjo	19	25	of	of	IN
cord-298458-p7rvupjo	19	26	the	the	DT
cord-298458-p7rvupjo	19	27	infected	infected	JJ
cord-298458-p7rvupjo	19	28	individual	individual	NN
cord-298458-p7rvupjo	19	29	.	.	.
cord-298458-p7rvupjo	20	1	Symptoms	symptom	NNS
cord-298458-p7rvupjo	20	2	can	can	MD
cord-298458-p7rvupjo	20	3	range	range	VB
cord-298458-p7rvupjo	20	4	from	from	IN
cord-298458-p7rvupjo	20	5	mild	mild	JJ
cord-298458-p7rvupjo	20	6	sinusitis	sinusitis	NN
cord-298458-p7rvupjo	20	7	or	or	CC
cord-298458-p7rvupjo	20	8	cold	cold	JJ
cord-298458-p7rvupjo	20	9	-	-	HYPH
cord-298458-p7rvupjo	20	10	like	like	JJ
cord-298458-p7rvupjo	20	11	symptoms	symptom	NNS
cord-298458-p7rvupjo	20	12	to	to	IN
cord-298458-p7rvupjo	20	13	more	more	RBR
cord-298458-p7rvupjo	20	14	severe	severe	JJ
cord-298458-p7rvupjo	20	15	symptoms	symptom	NNS
cord-298458-p7rvupjo	20	16	including	include	VBG
cord-298458-p7rvupjo	20	17	bronchitis	bronchitis	NN
cord-298458-p7rvupjo	20	18	,	,	,
cord-298458-p7rvupjo	20	19	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	20	20	,	,	,
cord-298458-p7rvupjo	20	21	and	and	CC
cord-298458-p7rvupjo	20	22	even	even	RB
cord-298458-p7rvupjo	20	23	death	death	NN
cord-298458-p7rvupjo	20	24	.	.	.
cord-298458-p7rvupjo	21	1	RSV	RSV	NNP
cord-298458-p7rvupjo	21	2	is	be	VBZ
cord-298458-p7rvupjo	21	3	the	the	DT
cord-298458-p7rvupjo	21	4	leading	leading	JJ
cord-298458-p7rvupjo	21	5	cause	cause	NN
cord-298458-p7rvupjo	21	6	of	of	IN
cord-298458-p7rvupjo	21	7	severe	severe	JJ
cord-298458-p7rvupjo	21	8	lower	low	JJR
cord-298458-p7rvupjo	21	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	21	10	tract	tract	NN
cord-298458-p7rvupjo	21	11	infection	infection	NN
cord-298458-p7rvupjo	21	12	in	in	IN
cord-298458-p7rvupjo	21	13	children	child	NNS
cord-298458-p7rvupjo	21	14	under	under	IN
cord-298458-p7rvupjo	21	15	5	5	CD
cord-298458-p7rvupjo	21	16	years	year	NNS
cord-298458-p7rvupjo	21	17	of	of	IN
cord-298458-p7rvupjo	21	18	age	age	NN
cord-298458-p7rvupjo	21	19	(	(	-LRB-
cord-298458-p7rvupjo	21	20	2	2	CD
cord-298458-p7rvupjo	21	21	)	)	-RRB-
cord-298458-p7rvupjo	21	22	.	.	.
cord-298458-p7rvupjo	22	1	RSV	RSV	NNP
cord-298458-p7rvupjo	22	2	is	be	VBZ
cord-298458-p7rvupjo	22	3	commonly	commonly	RB
cord-298458-p7rvupjo	22	4	associated	associate	VBN
cord-298458-p7rvupjo	22	5	with	with	IN
cord-298458-p7rvupjo	22	6	severe	severe	JJ
cord-298458-p7rvupjo	22	7	lower	low	JJR
cord-298458-p7rvupjo	22	8	respiratory	respiratory	JJ
cord-298458-p7rvupjo	22	9	tract	tract	NN
cord-298458-p7rvupjo	22	10	symptoms	symptom	NNS
cord-298458-p7rvupjo	22	11	including	include	VBG
cord-298458-p7rvupjo	22	12	bronchiolitis	bronchiolitis	NN
cord-298458-p7rvupjo	22	13	,	,	,
cord-298458-p7rvupjo	22	14	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	22	15	,	,	,
cord-298458-p7rvupjo	22	16	and	and	CC
cord-298458-p7rvupjo	22	17	bronchitis	bronchitis	NN
cord-298458-p7rvupjo	22	18	and	and	CC
cord-298458-p7rvupjo	22	19	is	be	VBZ
cord-298458-p7rvupjo	22	20	a	a	DT
cord-298458-p7rvupjo	22	21	significant	significant	JJ
cord-298458-p7rvupjo	22	22	cause	cause	NN
cord-298458-p7rvupjo	22	23	of	of	IN
cord-298458-p7rvupjo	22	24	hospitalization	hospitalization	NN
cord-298458-p7rvupjo	22	25	and	and	CC
cord-298458-p7rvupjo	22	26	mortality	mortality	NN
cord-298458-p7rvupjo	22	27	in	in	IN
cord-298458-p7rvupjo	22	28	children	child	NNS
cord-298458-p7rvupjo	22	29	,	,	,
cord-298458-p7rvupjo	22	30	the	the	DT
cord-298458-p7rvupjo	22	31	elderly	elderly	JJ
cord-298458-p7rvupjo	22	32	,	,	,
cord-298458-p7rvupjo	22	33	and	and	CC
cord-298458-p7rvupjo	22	34	immunocompromised	immunocompromised	JJ
cord-298458-p7rvupjo	22	35	individuals	individual	NNS
cord-298458-p7rvupjo	22	36	(	(	-LRB-
cord-298458-p7rvupjo	22	37	2	2	CD
cord-298458-p7rvupjo	22	38	)	)	-RRB-
cord-298458-p7rvupjo	22	39	(	(	-LRB-
cord-298458-p7rvupjo	22	40	3	3	LS
cord-298458-p7rvupjo	22	41	)	)	-RRB-
cord-298458-p7rvupjo	22	42	(	(	-LRB-
cord-298458-p7rvupjo	22	43	4	4	LS
cord-298458-p7rvupjo	22	44	)	)	-RRB-
cord-298458-p7rvupjo	22	45	(	(	-LRB-
cord-298458-p7rvupjo	22	46	5	5	LS
cord-298458-p7rvupjo	22	47	)	)	-RRB-
cord-298458-p7rvupjo	22	48	(	(	-LRB-
cord-298458-p7rvupjo	22	49	6	6	CD
cord-298458-p7rvupjo	22	50	)	)	-RRB-
cord-298458-p7rvupjo	22	51	.	.	.
cord-298458-p7rvupjo	23	1	Similarly	similarly	RB
cord-298458-p7rvupjo	23	2	,	,	,
cord-298458-p7rvupjo	23	3	PIV	PIV	NNP
cord-298458-p7rvupjo	23	4	commonly	commonly	RB
cord-298458-p7rvupjo	23	5	infects	infect	VBZ
cord-298458-p7rvupjo	23	6	children	child	NNS
cord-298458-p7rvupjo	23	7	and	and	CC
cord-298458-p7rvupjo	23	8	is	be	VBZ
cord-298458-p7rvupjo	23	9	a	a	DT
cord-298458-p7rvupjo	23	10	major	major	JJ
cord-298458-p7rvupjo	23	11	cause	cause	NN
cord-298458-p7rvupjo	23	12	of	of	IN
cord-298458-p7rvupjo	23	13	croup	croup	NN
cord-298458-p7rvupjo	23	14	,	,	,
cord-298458-p7rvupjo	23	15	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	23	16	,	,	,
cord-298458-p7rvupjo	23	17	and	and	CC
cord-298458-p7rvupjo	23	18	bronchiolitis	bronchiolitis	NNP
cord-298458-p7rvupjo	23	19	(	(	-LRB-
cord-298458-p7rvupjo	23	20	7	7	CD
cord-298458-p7rvupjo	23	21	,	,	,
cord-298458-p7rvupjo	23	22	8)	8)	NN
cord-298458-p7rvupjo	23	23	.	.	.
cord-298458-p7rvupjo	24	1	Seasonal	seasonal	JJ
cord-298458-p7rvupjo	24	2	influenza	influenza	NN
cord-298458-p7rvupjo	24	3	infections	infection	NNS
cord-298458-p7rvupjo	24	4	,	,	,
cord-298458-p7rvupjo	24	5	most	most	RBS
cord-298458-p7rvupjo	24	6	often	often	RB
cord-298458-p7rvupjo	24	7	of	of	IN
cord-298458-p7rvupjo	24	8	the	the	DT
cord-298458-p7rvupjo	24	9	influenza	influenza	NN
cord-298458-p7rvupjo	24	10	A	a	DT
cord-298458-p7rvupjo	24	11	virus	virus	NN
cord-298458-p7rvupjo	24	12	(	(	-LRB-
cord-298458-p7rvupjo	24	13	IAV	iav	NN
cord-298458-p7rvupjo	24	14	)	)	-RRB-
cord-298458-p7rvupjo	24	15	subtype	subtype	NN
cord-298458-p7rvupjo	24	16	,	,	,
cord-298458-p7rvupjo	24	17	are	be	VBP
cord-298458-p7rvupjo	24	18	responsible	responsible	JJ
cord-298458-p7rvupjo	24	19	for	for	IN
cord-298458-p7rvupjo	24	20	3	3	CD
cord-298458-p7rvupjo	24	21	-	-	SYM
cord-298458-p7rvupjo	24	22	5	5	CD
cord-298458-p7rvupjo	24	23	million	million	CD
cord-298458-p7rvupjo	24	24	cases	case	NNS
cord-298458-p7rvupjo	24	25	of	of	IN
cord-298458-p7rvupjo	24	26	severe	severe	JJ
cord-298458-p7rvupjo	24	27	infection	infection	NN
cord-298458-p7rvupjo	24	28	annually	annually	RB
cord-298458-p7rvupjo	24	29	(	(	-LRB-
cord-298458-p7rvupjo	24	30	9	9	CD
cord-298458-p7rvupjo	24	31	)	)	-RRB-
cord-298458-p7rvupjo	24	32	.	.	.
cord-298458-p7rvupjo	25	1	Seasonal	seasonal	JJ
cord-298458-p7rvupjo	25	2	IAV	IAV	NNP
cord-298458-p7rvupjo	25	3	infections	infection	NNS
cord-298458-p7rvupjo	25	4	also	also	RB
cord-298458-p7rvupjo	25	5	result	result	VBP
cord-298458-p7rvupjo	25	6	in	in	IN
cord-298458-p7rvupjo	25	7	approximately	approximately	RB
cord-298458-p7rvupjo	25	8	290,000	290,000	CD
cord-298458-p7rvupjo	25	9	-	-	HYPH
cord-298458-p7rvupjo	25	10	650,000	650,000	CD
cord-298458-p7rvupjo	25	11	deaths	death	NNS
cord-298458-p7rvupjo	25	12	per	per	IN
cord-298458-p7rvupjo	25	13	year	year	NN
cord-298458-p7rvupjo	25	14	,	,	,
cord-298458-p7rvupjo	25	15	most	most	RBS
cord-298458-p7rvupjo	25	16	commonly	commonly	RB
cord-298458-p7rvupjo	25	17	in	in	IN
cord-298458-p7rvupjo	25	18	either	either	DT
cord-298458-p7rvupjo	25	19	young	young	JJ
cord-298458-p7rvupjo	25	20	children	child	NNS
cord-298458-p7rvupjo	25	21	or	or	CC
cord-298458-p7rvupjo	25	22	elderly	elderly	JJ
cord-298458-p7rvupjo	25	23	populations	population	NNS
cord-298458-p7rvupjo	25	24	(	(	-LRB-
cord-298458-p7rvupjo	25	25	9	9	CD
cord-298458-p7rvupjo	25	26	)	)	-RRB-
cord-298458-p7rvupjo	25	27	(	(	-LRB-
cord-298458-p7rvupjo	25	28	10	10	CD
cord-298458-p7rvupjo	25	29	)	)	-RRB-
cord-298458-p7rvupjo	25	30	(	(	-LRB-
cord-298458-p7rvupjo	25	31	11	11	CD
cord-298458-p7rvupjo	25	32	)	)	-RRB-
cord-298458-p7rvupjo	25	33	.	.	.
cord-298458-p7rvupjo	26	1	However	however	RB
cord-298458-p7rvupjo	26	2	,	,	,
cord-298458-p7rvupjo	26	3	infection	infection	NN
cord-298458-p7rvupjo	26	4	with	with	IN
cord-298458-p7rvupjo	26	5	emerging	emerge	VBG
cord-298458-p7rvupjo	26	6	pandemic	pandemic	NN
cord-298458-p7rvupjo	26	7	IAV	IAV	NNP
cord-298458-p7rvupjo	26	8	strains	strain	NNS
cord-298458-p7rvupjo	26	9	,	,	,
cord-298458-p7rvupjo	26	10	such	such	JJ
cord-298458-p7rvupjo	26	11	as	as	IN
cord-298458-p7rvupjo	26	12	the	the	DT
cord-298458-p7rvupjo	26	13	2009	2009	CD
cord-298458-p7rvupjo	26	14	H1N1	H1N1	NNP
cord-298458-p7rvupjo	26	15	pandemic	pandemic	NN
cord-298458-p7rvupjo	26	16	strain	strain	NN
cord-298458-p7rvupjo	26	17	,	,	,
cord-298458-p7rvupjo	26	18	primarily	primarily	RB
cord-298458-p7rvupjo	26	19	induces	induce	VBZ
cord-298458-p7rvupjo	26	20	severe	severe	JJ
cord-298458-p7rvupjo	26	21	disease	disease	NN
cord-298458-p7rvupjo	26	22	and	and	CC
cord-298458-p7rvupjo	26	23	mortality	mortality	NN
cord-298458-p7rvupjo	26	24	in	in	IN
cord-298458-p7rvupjo	26	25	otherwise	otherwise	RB
cord-298458-p7rvupjo	26	26	healthy	healthy	JJ
cord-298458-p7rvupjo	26	27	adults	adult	NNS
cord-298458-p7rvupjo	26	28	younger	young	JJR
cord-298458-p7rvupjo	26	29	than	than	IN
cord-298458-p7rvupjo	26	30	65	65	CD
cord-298458-p7rvupjo	26	31	years	year	NNS
cord-298458-p7rvupjo	26	32	of	of	IN
cord-298458-p7rvupjo	26	33	age	age	NN
cord-298458-p7rvupjo	26	34	(	(	-LRB-
cord-298458-p7rvupjo	26	35	12	12	CD
cord-298458-p7rvupjo	26	36	)	)	-RRB-
cord-298458-p7rvupjo	26	37	.	.	.
cord-298458-p7rvupjo	27	1	In	in	IN
cord-298458-p7rvupjo	27	2	contrast	contrast	NN
cord-298458-p7rvupjo	27	3	,	,	,
cord-298458-p7rvupjo	27	4	respiratory	respiratory	JJ
cord-298458-p7rvupjo	27	5	infection	infection	NN
cord-298458-p7rvupjo	27	6	with	with	IN
cord-298458-p7rvupjo	27	7	HMPV	HMPV	NNP
cord-298458-p7rvupjo	27	8	,	,	,
cord-298458-p7rvupjo	27	9	RV	RV	NNP
cord-298458-p7rvupjo	27	10	,	,	,
cord-298458-p7rvupjo	27	11	and	and	CC
cord-298458-p7rvupjo	27	12	CoV	CoV	NNP
cord-298458-p7rvupjo	27	13	are	be	VBP
cord-298458-p7rvupjo	27	14	most	most	RBS
cord-298458-p7rvupjo	27	15	commonly	commonly	RB
cord-298458-p7rvupjo	27	16	associated	associate	VBN
cord-298458-p7rvupjo	27	17	with	with	IN
cord-298458-p7rvupjo	27	18	symptoms	symptom	NNS
cord-298458-p7rvupjo	27	19	of	of	IN
cord-298458-p7rvupjo	27	20	the	the	DT
cord-298458-p7rvupjo	27	21	common	common	JJ
cord-298458-p7rvupjo	27	22	cold	cold	NN
cord-298458-p7rvupjo	27	23	(	(	-LRB-
cord-298458-p7rvupjo	27	24	13	13	CD
cord-298458-p7rvupjo	27	25	)	)	-RRB-
cord-298458-p7rvupjo	27	26	(	(	-LRB-
cord-298458-p7rvupjo	27	27	14	14	CD
cord-298458-p7rvupjo	27	28	)	)	-RRB-
cord-298458-p7rvupjo	27	29	(	(	-LRB-
cord-298458-p7rvupjo	27	30	15	15	CD
cord-298458-p7rvupjo	27	31	)	)	-RRB-
cord-298458-p7rvupjo	27	32	.	.	.
cord-298458-p7rvupjo	28	1	Two	two	CD
cord-298458-p7rvupjo	28	2	notable	notable	JJ
cord-298458-p7rvupjo	28	3	exceptions	exception	NNS
cord-298458-p7rvupjo	28	4	are	be	VBP
cord-298458-p7rvupjo	28	5	severe	severe	JJ
cord-298458-p7rvupjo	28	6	acute	acute	JJ
cord-298458-p7rvupjo	28	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	28	8	syndrome	syndrome	NN
cord-298458-p7rvupjo	28	9	(	(	-LRB-
cord-298458-p7rvupjo	28	10	SARS	SARS	NNP
cord-298458-p7rvupjo	28	11	)	)	-RRB-
cord-298458-p7rvupjo	28	12	CoV	CoV	NNP
cord-298458-p7rvupjo	28	13	and	and	CC
cord-298458-p7rvupjo	28	14	Middle	Middle	NNP
cord-298458-p7rvupjo	28	15	East	East	NNP
cord-298458-p7rvupjo	28	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	28	17	syndrome	syndrome	NN
cord-298458-p7rvupjo	28	18	(	(	-LRB-
cord-298458-p7rvupjo	28	19	MERS	MERS	NNP
cord-298458-p7rvupjo	28	20	)	)	-RRB-
cord-298458-p7rvupjo	28	21	CoV	CoV	NNP
cord-298458-p7rvupjo	28	22	,	,	,
cord-298458-p7rvupjo	28	23	which	which	WDT
cord-298458-p7rvupjo	28	24	cause	cause	VBP
cord-298458-p7rvupjo	28	25	acute	acute	JJ
cord-298458-p7rvupjo	28	26	respi	respi	NNP
cord-298458-p7rvupjo	28	27	ratory	ratory	JJ
cord-298458-p7rvupjo	28	28	distress	distress	NN
cord-298458-p7rvupjo	28	29	and	and	CC
cord-298458-p7rvupjo	28	30	mortality	mortality	NN
cord-298458-p7rvupjo	28	31	in	in	IN
cord-298458-p7rvupjo	28	32	infected	infected	JJ
cord-298458-p7rvupjo	28	33	individuals	individual	NNS
cord-298458-p7rvupjo	28	34	(	(	-LRB-
cord-298458-p7rvupjo	28	35	16	16	CD
cord-298458-p7rvupjo	28	36	)	)	-RRB-
cord-298458-p7rvupjo	29	1	(	(	-LRB-
cord-298458-p7rvupjo	29	2	17	17	CD
cord-298458-p7rvupjo	29	3	)	)	-RRB-
cord-298458-p7rvupjo	29	4	(	(	-LRB-
cord-298458-p7rvupjo	29	5	18	18	CD
cord-298458-p7rvupjo	29	6	)	)	-RRB-
cord-298458-p7rvupjo	29	7	.	.	.
cord-298458-p7rvupjo	30	1	Despite	despite	IN
cord-298458-p7rvupjo	30	2	their	-PRON-	PRP$
cord-298458-p7rvupjo	30	3	profound	profound	JJ
cord-298458-p7rvupjo	30	4	impact	impact	NN
cord-298458-p7rvupjo	30	5	on	on	IN
cord-298458-p7rvupjo	30	6	human	human	JJ
cord-298458-p7rvupjo	30	7	health	health	NN
cord-298458-p7rvupjo	30	8	,	,	,
cord-298458-p7rvupjo	30	9	most	most	RBS
cord-298458-p7rvupjo	30	10	common	common	JJ
cord-298458-p7rvupjo	30	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	30	12	viruses	virus	NNS
cord-298458-p7rvupjo	30	13	lack	lack	VBP
cord-298458-p7rvupjo	30	14	an	an	DT
cord-298458-p7rvupjo	30	15	approved	approve	VBN
cord-298458-p7rvupjo	30	16	vaccine	vaccine	NN
cord-298458-p7rvupjo	30	17	.	.	.
cord-298458-p7rvupjo	31	1	The	the	DT
cord-298458-p7rvupjo	31	2	strategy	strategy	NN
cord-298458-p7rvupjo	31	3	employed	employ	VBD
cord-298458-p7rvupjo	31	4	most	most	RBS
cord-298458-p7rvupjo	31	5	often	often	RB
cord-298458-p7rvupjo	31	6	in	in	IN
cord-298458-p7rvupjo	31	7	vaccine	vaccine	NN
cord-298458-p7rvupjo	31	8	development	development	NN
cord-298458-p7rvupjo	31	9	is	be	VBZ
cord-298458-p7rvupjo	31	10	the	the	DT
cord-298458-p7rvupjo	31	11	induction	induction	NN
cord-298458-p7rvupjo	31	12	of	of	IN
cord-298458-p7rvupjo	31	13	robust	robust	JJ
cord-298458-p7rvupjo	31	14	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	31	15	antibody	antibody	NN
cord-298458-p7rvupjo	31	16	responses	response	NNS
cord-298458-p7rvupjo	31	17	.	.	.
cord-298458-p7rvupjo	32	1	However	however	RB
cord-298458-p7rvupjo	32	2	,	,	,
cord-298458-p7rvupjo	32	3	the	the	DT
cord-298458-p7rvupjo	32	4	hallmark	hallmark	NN
cord-298458-p7rvupjo	32	5	of	of	IN
cord-298458-p7rvupjo	32	6	many	many	JJ
cord-298458-p7rvupjo	32	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	32	8	viral	viral	JJ
cord-298458-p7rvupjo	32	9	infections	infection	NNS
cord-298458-p7rvupjo	32	10	,	,	,
cord-298458-p7rvupjo	32	11	including	include	VBG
cord-298458-p7rvupjo	32	12	RSV	RSV	NNP
cord-298458-p7rvupjo	32	13	,	,	,
cord-298458-p7rvupjo	32	14	HMPV	HMPV	NNP
cord-298458-p7rvupjo	32	15	,	,	,
cord-298458-p7rvupjo	32	16	and	and	CC
cord-298458-p7rvupjo	32	17	RV	RV	NNP
cord-298458-p7rvupjo	32	18	,	,	,
cord-298458-p7rvupjo	32	19	is	be	VBZ
cord-298458-p7rvupjo	32	20	the	the	DT
cord-298458-p7rvupjo	32	21	ability	ability	NN
cord-298458-p7rvupjo	32	22	for	for	IN
cord-298458-p7rvupjo	32	23	reinfections	reinfection	NNS
cord-298458-p7rvupjo	32	24	to	to	TO
cord-298458-p7rvupjo	32	25	occur	occur	VB
cord-298458-p7rvupjo	32	26	frequently	frequently	RB
cord-298458-p7rvupjo	32	27	throughout	throughout	IN
cord-298458-p7rvupjo	32	28	life	life	NN
cord-298458-p7rvupjo	32	29	(	(	-LRB-
cord-298458-p7rvupjo	32	30	19	19	CD
cord-298458-p7rvupjo	32	31	)	)	-RRB-
cord-298458-p7rvupjo	32	32	(	(	-LRB-
cord-298458-p7rvupjo	32	33	20	20	CD
cord-298458-p7rvupjo	32	34	)	)	-RRB-
cord-298458-p7rvupjo	32	35	(	(	-LRB-
cord-298458-p7rvupjo	32	36	21	21	CD
cord-298458-p7rvupjo	32	37	)	)	-RRB-
cord-298458-p7rvupjo	32	38	.	.	.
cord-298458-p7rvupjo	33	1	This	this	DT
cord-298458-p7rvupjo	33	2	suggests	suggest	VBZ
cord-298458-p7rvupjo	33	3	that	that	IN
cord-298458-p7rvupjo	33	4	the	the	DT
cord-298458-p7rvupjo	33	5	antibody	antibody	NN
cord-298458-p7rvupjo	33	6	response	response	NN
cord-298458-p7rvupjo	33	7	to	to	IN
cord-298458-p7rvupjo	33	8	these	these	DT
cord-298458-p7rvupjo	33	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	33	10	viruses	virus	NNS
cord-298458-p7rvupjo	33	11	may	may	MD
cord-298458-p7rvupjo	33	12	wane	wane	VB
cord-298458-p7rvupjo	33	13	over	over	IN
cord-298458-p7rvupjo	33	14	time	time	NN
cord-298458-p7rvupjo	33	15	.	.	.
cord-298458-p7rvupjo	34	1	Indeed	indeed	RB
cord-298458-p7rvupjo	34	2	,	,	,
cord-298458-p7rvupjo	34	3	despite	despite	IN
cord-298458-p7rvupjo	34	4	a	a	DT
cord-298458-p7rvupjo	34	5	correlation	correlation	NN
cord-298458-p7rvupjo	34	6	between	between	IN
cord-298458-p7rvupjo	34	7	pre	pre	JJ
cord-298458-p7rvupjo	34	8	-	-	JJ
cord-298458-p7rvupjo	34	9	existing	existing	JJ
cord-298458-p7rvupjo	34	10	nasal	nasal	NN
cord-298458-p7rvupjo	34	11	IgA	IgA	NNP
cord-298458-p7rvupjo	34	12	and	and	CC
cord-298458-p7rvupjo	34	13	protection	protection	NN
cord-298458-p7rvupjo	34	14	from	from	IN
cord-298458-p7rvupjo	34	15	reinfection	reinfection	NN
cord-298458-p7rvupjo	34	16	,	,	,
cord-298458-p7rvupjo	34	17	the	the	DT
cord-298458-p7rvupjo	34	18	development	development	NN
cord-298458-p7rvupjo	34	19	of	of	IN
cord-298458-p7rvupjo	34	20	long	long	RB
cord-298458-p7rvupjo	34	21	-	-	HYPH
cord-298458-p7rvupjo	34	22	lasting	last	VBG
cord-298458-p7rvupjo	34	23	RSV	RSV	NNP
cord-298458-p7rvupjo	34	24	-	-	HYPH
cord-298458-p7rvupjo	34	25	and	and	CC
cord-298458-p7rvupjo	34	26	RV	rv	NN
cord-298458-p7rvupjo	34	27	-	-	HYPH
cord-298458-p7rvupjo	34	28	specific	specific	JJ
cord-298458-p7rvupjo	34	29	mucosal	mucosal	JJ
cord-298458-p7rvupjo	34	30	IgA	IgA	NNP
cord-298458-p7rvupjo	34	31	responses	response	NNS
cord-298458-p7rvupjo	34	32	was	be	VBD
cord-298458-p7rvupjo	34	33	poor	poor	JJ
cord-298458-p7rvupjo	34	34	in	in	IN
cord-298458-p7rvupjo	34	35	infected	infected	JJ
cord-298458-p7rvupjo	34	36	adults	adult	NNS
cord-298458-p7rvupjo	34	37	(	(	-LRB-
cord-298458-p7rvupjo	34	38	22	22	CD
cord-298458-p7rvupjo	34	39	,	,	,
cord-298458-p7rvupjo	34	40	23	23	CD
cord-298458-p7rvupjo	34	41	)	)	-RRB-
cord-298458-p7rvupjo	34	42	.	.	.
cord-298458-p7rvupjo	35	1	Although	although	IN
cord-298458-p7rvupjo	35	2	IAV	iav	NN
cord-298458-p7rvupjo	35	3	-	-	HYPH
cord-298458-p7rvupjo	35	4	specific	specific	JJ
cord-298458-p7rvupjo	35	5	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	35	6	antibodies	antibody	NNS
cord-298458-p7rvupjo	35	7	are	be	VBP
cord-298458-p7rvupjo	35	8	elicited	elicit	VBN
cord-298458-p7rvupjo	35	9	efficiently	efficiently	RB
cord-298458-p7rvupjo	35	10	through	through	IN
cord-298458-p7rvupjo	35	11	either	either	CC
cord-298458-p7rvupjo	35	12	infection	infection	NN
cord-298458-p7rvupjo	35	13	or	or	CC
cord-298458-p7rvupjo	35	14	vaccination	vaccination	NN
cord-298458-p7rvupjo	35	15	,	,	,
cord-298458-p7rvupjo	35	16	IAV	IAV	NNP
cord-298458-p7rvupjo	35	17	vaccine	vaccine	NN
cord-298458-p7rvupjo	35	18	formulations	formulation	NNS
cord-298458-p7rvupjo	35	19	must	must	MD
cord-298458-p7rvupjo	35	20	be	be	VB
cord-298458-p7rvupjo	35	21	redeveloped	redevelop	VBN
cord-298458-p7rvupjo	35	22	annually	annually	RB
cord-298458-p7rvupjo	35	23	to	to	TO
cord-298458-p7rvupjo	35	24	account	account	VB
cord-298458-p7rvupjo	35	25	for	for	IN
cord-298458-p7rvupjo	35	26	the	the	DT
cord-298458-p7rvupjo	35	27	rapid	rapid	JJ
cord-298458-p7rvupjo	35	28	mutations	mutation	NNS
cord-298458-p7rvupjo	35	29	of	of	IN
cord-298458-p7rvupjo	35	30	HA	HA	NNP
cord-298458-p7rvupjo	35	31	and	and	CC
cord-298458-p7rvupjo	35	32	NA	NA	NNP
cord-298458-p7rvupjo	35	33	genes	gene	NNS
cord-298458-p7rvupjo	35	34	in	in	IN
cord-298458-p7rvupjo	35	35	seasonal	seasonal	JJ
cord-298458-p7rvupjo	35	36	strains	strain	NNS
cord-298458-p7rvupjo	35	37	(	(	-LRB-
cord-298458-p7rvupjo	35	38	24	24	CD
cord-298458-p7rvupjo	35	39	)	)	-RRB-
cord-298458-p7rvupjo	35	40	.	.	.
cord-298458-p7rvupjo	36	1	Therefore	therefore	RB
cord-298458-p7rvupjo	36	2	,	,	,
cord-298458-p7rvupjo	36	3	vaccinations	vaccination	NNS
cord-298458-p7rvupjo	36	4	that	that	WDT
cord-298458-p7rvupjo	36	5	solely	solely	RB
cord-298458-p7rvupjo	36	6	promote	promote	VBP
cord-298458-p7rvupjo	36	7	the	the	DT
cord-298458-p7rvupjo	36	8	induction	induction	NN
cord-298458-p7rvupjo	36	9	of	of	IN
cord-298458-p7rvupjo	36	10	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	36	11	antibodies	antibody	NNS
cord-298458-p7rvupjo	36	12	may	may	MD
cord-298458-p7rvupjo	36	13	not	not	RB
cord-298458-p7rvupjo	36	14	be	be	VB
cord-298458-p7rvupjo	36	15	optimal	optimal	JJ
cord-298458-p7rvupjo	36	16	in	in	IN
cord-298458-p7rvupjo	36	17	providing	provide	VBG
cord-298458-p7rvupjo	36	18	protection	protection	NN
cord-298458-p7rvupjo	36	19	against	against	IN
cord-298458-p7rvupjo	36	20	many	many	JJ
cord-298458-p7rvupjo	36	21	respiratory	respiratory	JJ
cord-298458-p7rvupjo	36	22	virus	virus	NN
cord-298458-p7rvupjo	36	23	infections	infection	NNS
cord-298458-p7rvupjo	36	24	.	.	.
cord-298458-p7rvupjo	37	1	The	the	DT
cord-298458-p7rvupjo	37	2	induction	induction	NN
cord-298458-p7rvupjo	37	3	of	of	IN
cord-298458-p7rvupjo	37	4	cellular	cellular	JJ
cord-298458-p7rvupjo	37	5	immune	immune	JJ
cord-298458-p7rvupjo	37	6	responses	response	NNS
cord-298458-p7rvupjo	37	7	has	have	VBZ
cord-298458-p7rvupjo	37	8	thus	thus	RB
cord-298458-p7rvupjo	37	9	far	far	RB
cord-298458-p7rvupjo	37	10	received	receive	VBN
cord-298458-p7rvupjo	37	11	little	little	JJ
cord-298458-p7rvupjo	37	12	attention	attention	NN
cord-298458-p7rvupjo	37	13	in	in	IN
cord-298458-p7rvupjo	37	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	37	15	virus	virus	NN
cord-298458-p7rvupjo	37	16	vaccine	vaccine	NN
cord-298458-p7rvupjo	37	17	development	development	NN
cord-298458-p7rvupjo	37	18	.	.	.
cord-298458-p7rvupjo	38	1	CD8	CD8	NNP
cord-298458-p7rvupjo	38	2	T	T	NNP
cord-298458-p7rvupjo	38	3	cells	cell	NNS
cord-298458-p7rvupjo	38	4	play	play	VBP
cord-298458-p7rvupjo	38	5	a	a	DT
cord-298458-p7rvupjo	38	6	critical	critical	JJ
cord-298458-p7rvupjo	38	7	role	role	NN
cord-298458-p7rvupjo	38	8	in	in	IN
cord-298458-p7rvupjo	38	9	mediating	mediate	VBG
cord-298458-p7rvupjo	38	10	viral	viral	JJ
cord-298458-p7rvupjo	38	11	clearance	clearance	NN
cord-298458-p7rvupjo	38	12	following	follow	VBG
cord-298458-p7rvupjo	38	13	many	many	JJ
cord-298458-p7rvupjo	38	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	38	15	virus	virus	NN
cord-298458-p7rvupjo	38	16	infections	infection	NNS
cord-298458-p7rvupjo	38	17	including	include	VBG
cord-298458-p7rvupjo	38	18	RSV	RSV	NNP
cord-298458-p7rvupjo	38	19	,	,	,
cord-298458-p7rvupjo	38	20	IAV	IAV	NNP
cord-298458-p7rvupjo	38	21	,	,	,
cord-298458-p7rvupjo	38	22	and	and	CC
cord-298458-p7rvupjo	38	23	HMPV	HMPV	NNP
cord-298458-p7rvupjo	38	24	(	(	-LRB-
cord-298458-p7rvupjo	38	25	25	25	CD
cord-298458-p7rvupjo	38	26	)	)	-RRB-
cord-298458-p7rvupjo	38	27	(	(	-LRB-
cord-298458-p7rvupjo	38	28	26	26	CD
cord-298458-p7rvupjo	38	29	)	)	-RRB-
cord-298458-p7rvupjo	38	30	(	(	-LRB-
cord-298458-p7rvupjo	38	31	27	27	CD
cord-298458-p7rvupjo	38	32	)	)	-RRB-
cord-298458-p7rvupjo	38	33	.	.	.
cord-298458-p7rvupjo	39	1	In	in	IN
cord-298458-p7rvupjo	39	2	addition	addition	NN
cord-298458-p7rvupjo	39	3	,	,	,
cord-298458-p7rvupjo	39	4	recent	recent	JJ
cord-298458-p7rvupjo	39	5	murine	murine	JJ
cord-298458-p7rvupjo	39	6	studies	study	NNS
cord-298458-p7rvupjo	39	7	utilizing	utilize	VBG
cord-298458-p7rvupjo	39	8	CD8	CD8	NNP
cord-298458-p7rvupjo	39	9	T	T	NNP
cord-298458-p7rvupjo	39	10	cell	cell	NN
cord-298458-p7rvupjo	39	11	epitope	epitope	NN
cord-298458-p7rvupjo	39	12	-	-	HYPH
cord-298458-p7rvupjo	39	13	specific	specific	JJ
cord-298458-p7rvupjo	39	14	immunization	immunization	NN
cord-298458-p7rvupjo	39	15	strategies	strategy	NNS
cord-298458-p7rvupjo	39	16	observed	observe	VBD
cord-298458-p7rvupjo	39	17	significantly	significantly	RB
cord-298458-p7rvupjo	39	18	reduced	reduce	VBD
cord-298458-p7rvupjo	39	19	lung	lung	NN
cord-298458-p7rvupjo	39	20	viral	viral	JJ
cord-298458-p7rvupjo	39	21	titers	titer	NNS
cord-298458-p7rvupjo	39	22	following	follow	VBG
cord-298458-p7rvupjo	39	23	IAV	IAV	NNP
cord-298458-p7rvupjo	39	24	,	,	,
cord-298458-p7rvupjo	39	25	RSV	RSV	NNP
cord-298458-p7rvupjo	39	26	,	,	,
cord-298458-p7rvupjo	39	27	or	or	CC
cord-298458-p7rvupjo	39	28	SARS	SARS	NNP
cord-298458-p7rvupjo	39	29	challenges	challenge	NNS
cord-298458-p7rvupjo	39	30	(	(	-LRB-
cord-298458-p7rvupjo	39	31	28	28	CD
cord-298458-p7rvupjo	39	32	)	)	-RRB-
cord-298458-p7rvupjo	39	33	(	(	-LRB-
cord-298458-p7rvupjo	39	34	29	29	CD
cord-298458-p7rvupjo	39	35	)	)	-RRB-
cord-298458-p7rvupjo	39	36	(	(	-LRB-
cord-298458-p7rvupjo	39	37	30	30	CD
cord-298458-p7rvupjo	39	38	)	)	-RRB-
cord-298458-p7rvupjo	39	39	.	.	.
cord-298458-p7rvupjo	40	1	Therefore	therefore	RB
cord-298458-p7rvupjo	40	2	,	,	,
cord-298458-p7rvupjo	40	3	the	the	DT
cord-298458-p7rvupjo	40	4	induction	induction	NN
cord-298458-p7rvupjo	40	5	of	of	IN
cord-298458-p7rvupjo	40	6	virus	virus	NN
cord-298458-p7rvupjo	40	7	-	-	HYPH
cord-298458-p7rvupjo	40	8	specific	specific	JJ
cord-298458-p7rvupjo	40	9	CD8	CD8	NNP
cord-298458-p7rvupjo	40	10	T	T	NNP
cord-298458-p7rvupjo	40	11	cell	cell	NN
cord-298458-p7rvupjo	40	12	responses	response	NNS
cord-298458-p7rvupjo	40	13	has	have	VBZ
cord-298458-p7rvupjo	40	14	the	the	DT
cord-298458-p7rvupjo	40	15	potential	potential	NN
cord-298458-p7rvupjo	40	16	to	to	TO
cord-298458-p7rvupjo	40	17	improve	improve	VB
cord-298458-p7rvupjo	40	18	upon	upon	IN
cord-298458-p7rvupjo	40	19	the	the	DT
cord-298458-p7rvupjo	40	20	efficacy	efficacy	NN
cord-298458-p7rvupjo	40	21	of	of	IN
cord-298458-p7rvupjo	40	22	current	current	JJ
cord-298458-p7rvupjo	40	23	vaccination	vaccination	NN
cord-298458-p7rvupjo	40	24	strategies	strategy	NNS
cord-298458-p7rvupjo	40	25	.	.	.
cord-298458-p7rvupjo	41	1	Here	here	RB
cord-298458-p7rvupjo	41	2	,	,	,
cord-298458-p7rvupjo	41	3	we	-PRON-	PRP
cord-298458-p7rvupjo	41	4	review	review	VBP
cord-298458-p7rvupjo	41	5	the	the	DT
cord-298458-p7rvupjo	41	6	current	current	JJ
cord-298458-p7rvupjo	41	7	literature	literature	NN
cord-298458-p7rvupjo	41	8	on	on	IN
cord-298458-p7rvupjo	41	9	CD8	CD8	NNP
cord-298458-p7rvupjo	41	10	T	T	NNP
cord-298458-p7rvupjo	41	11	cell	cell	NN
cord-298458-p7rvupjo	41	12	responses	response	NNS
cord-298458-p7rvupjo	41	13	following	follow	VBG
cord-298458-p7rvupjo	41	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	41	15	virus	virus	NN
cord-298458-p7rvupjo	41	16	infections	infection	NNS
cord-298458-p7rvupjo	41	17	and	and	CC
cord-298458-p7rvupjo	41	18	discuss	discuss	VB
cord-298458-p7rvupjo	41	19	how	how	WRB
cord-298458-p7rvupjo	41	20	this	this	DT
cord-298458-p7rvupjo	41	21	knowledge	knowledge	NN
cord-298458-p7rvupjo	41	22	may	may	MD
cord-298458-p7rvupjo	41	23	best	best	RB
cord-298458-p7rvupjo	41	24	be	be	VB
cord-298458-p7rvupjo	41	25	utilized	utilize	VBN
cord-298458-p7rvupjo	41	26	in	in	IN
cord-298458-p7rvupjo	41	27	the	the	DT
cord-298458-p7rvupjo	41	28	development	development	NN
cord-298458-p7rvupjo	41	29	of	of	IN
cord-298458-p7rvupjo	41	30	future	future	JJ
cord-298458-p7rvupjo	41	31	vaccines	vaccine	NNS
cord-298458-p7rvupjo	41	32	.	.	.
cord-298458-p7rvupjo	42	1	Following	follow	VBG
cord-298458-p7rvupjo	42	2	an	an	DT
cord-298458-p7rvupjo	42	3	acute	acute	JJ
cord-298458-p7rvupjo	42	4	respiratory	respiratory	JJ
cord-298458-p7rvupjo	42	5	infection	infection	NN
cord-298458-p7rvupjo	42	6	,	,	,
cord-298458-p7rvupjo	42	7	dendritic	dendritic	JJ
cord-298458-p7rvupjo	42	8	cells	cell	NNS
cord-298458-p7rvupjo	42	9	(	(	-LRB-
cord-298458-p7rvupjo	42	10	DCs	DCs	NNP
cord-298458-p7rvupjo	42	11	)	)	-RRB-
cord-298458-p7rvupjo	42	12	that	that	WDT
cord-298458-p7rvupjo	42	13	have	have	VBP
cord-298458-p7rvupjo	42	14	taken	take	VBN
cord-298458-p7rvupjo	42	15	up	up	RP
cord-298458-p7rvupjo	42	16	viral	viral	JJ
cord-298458-p7rvupjo	42	17	antigen	antigen	NN
cord-298458-p7rvupjo	42	18	stimulate	stimulate	VBP
cord-298458-p7rvupjo	42	19	the	the	DT
cord-298458-p7rvupjo	42	20	activation	activation	NN
cord-298458-p7rvupjo	42	21	of	of	IN
cord-298458-p7rvupjo	42	22	naive	naive	JJ
cord-298458-p7rvupjo	42	23	CD8	CD8	NNP
cord-298458-p7rvupjo	42	24	T	T	NNP
cord-298458-p7rvupjo	42	25	cells	cell	NNS
cord-298458-p7rvupjo	42	26	in	in	IN
cord-298458-p7rvupjo	42	27	the	the	DT
cord-298458-p7rvupjo	42	28	lung	lung	NN
cord-298458-p7rvupjo	42	29	draining	drain	VBG
cord-298458-p7rvupjo	42	30	lymph	lymph	NN
cord-298458-p7rvupjo	42	31	node	node	NN
cord-298458-p7rvupjo	42	32	to	to	TO
cord-298458-p7rvupjo	42	33	induce	induce	VB
cord-298458-p7rvupjo	42	34	robust	robust	JJ
cord-298458-p7rvupjo	42	35	virus	virus	NN
cord-298458-p7rvupjo	42	36	-	-	HYPH
cord-298458-p7rvupjo	42	37	specific	specific	JJ
cord-298458-p7rvupjo	42	38	CD8	CD8	NNP
cord-298458-p7rvupjo	42	39	T	T	NNP
cord-298458-p7rvupjo	42	40	cell	cell	NN
cord-298458-p7rvupjo	42	41	responses	response	NNS
cord-298458-p7rvupjo	42	42	[	[	-LRB-
cord-298458-p7rvupjo	42	43	reviewed	review	VBN
cord-298458-p7rvupjo	42	44	in	in	IN
cord-298458-p7rvupjo	42	45	Ref	Ref	NNP
cord-298458-p7rvupjo	42	46	.	.	.
cord-298458-p7rvupjo	43	1	(	(	-LRB-
cord-298458-p7rvupjo	43	2	31	31	CD
cord-298458-p7rvupjo	43	3	)	)	-RRB-
cord-298458-p7rvupjo	43	4	(	(	-LRB-
cord-298458-p7rvupjo	43	5	32	32	CD
cord-298458-p7rvupjo	43	6	)	)	-RRB-
cord-298458-p7rvupjo	43	7	(	(	-LRB-
cord-298458-p7rvupjo	43	8	33	33	CD
cord-298458-p7rvupjo	43	9	)	)	-RRB-
cord-298458-p7rvupjo	43	10	]	]	-RRB-
cord-298458-p7rvupjo	43	11	.	.	.
cord-298458-p7rvupjo	44	1	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	44	2	virus	virus	NN
cord-298458-p7rvupjo	44	3	infection	infection	NN
cord-298458-p7rvupjo	44	4	in	in	IN
cord-298458-p7rvupjo	44	5	mouse	mouse	NN
cord-298458-p7rvupjo	44	6	models	model	NNS
cord-298458-p7rvupjo	44	7	results	result	VBZ
cord-298458-p7rvupjo	44	8	in	in	IN
cord-298458-p7rvupjo	44	9	an	an	DT
cord-298458-p7rvupjo	44	10	increase	increase	NN
cord-298458-p7rvupjo	44	11	in	in	IN
cord-298458-p7rvupjo	44	12	the	the	DT
cord-298458-p7rvupjo	44	13	frequency	frequency	NN
cord-298458-p7rvupjo	44	14	and	and	CC
cord-298458-p7rvupjo	44	15	number	number	NN
cord-298458-p7rvupjo	44	16	of	of	IN
cord-298458-p7rvupjo	44	17	total	total	JJ
cord-298458-p7rvupjo	44	18	and	and	CC
cord-298458-p7rvupjo	44	19	antigenspecific	antigenspecific	NNP
cord-298458-p7rvupjo	44	20	CD8	CD8	NNP
cord-298458-p7rvupjo	44	21	T	T	NNP
cord-298458-p7rvupjo	44	22	cells	cell	NNS
cord-298458-p7rvupjo	44	23	in	in	IN
cord-298458-p7rvupjo	44	24	the	the	DT
cord-298458-p7rvupjo	44	25	lungs	lung	NNS
cord-298458-p7rvupjo	44	26	and	and	CC
cord-298458-p7rvupjo	44	27	airways	airway	NNS
cord-298458-p7rvupjo	44	28	.	.	.
cord-298458-p7rvupjo	45	1	RSV	RSV	NNP
cord-298458-p7rvupjo	45	2	-	-	HYPH
cord-298458-p7rvupjo	45	3	specific	specific	JJ
cord-298458-p7rvupjo	45	4	CD8	CD8	NNP
cord-298458-p7rvupjo	45	5	T	T	NNP
cord-298458-p7rvupjo	45	6	cell	cell	NN
cord-298458-p7rvupjo	45	7	responses	response	NNS
cord-298458-p7rvupjo	45	8	typically	typically	RB
cord-298458-p7rvupjo	45	9	reach	reach	VBP
cord-298458-p7rvupjo	45	10	peak	peak	NN
cord-298458-p7rvupjo	45	11	numbers	number	NNS
cord-298458-p7rvupjo	45	12	in	in	IN
cord-298458-p7rvupjo	45	13	the	the	DT
cord-298458-p7rvupjo	45	14	lung	lung	NN
cord-298458-p7rvupjo	45	15	at	at	IN
cord-298458-p7rvupjo	45	16	approximately	approximately	RB
cord-298458-p7rvupjo	45	17	day	day	NN
cord-298458-p7rvupjo	45	18	8	8	CD
cord-298458-p7rvupjo	45	19	following	follow	VBG
cord-298458-p7rvupjo	45	20	an	an	DT
cord-298458-p7rvupjo	45	21	acute	acute	JJ
cord-298458-p7rvupjo	45	22	infection	infection	NN
cord-298458-p7rvupjo	45	23	(	(	-LRB-
cord-298458-p7rvupjo	45	24	34	34	CD
cord-298458-p7rvupjo	45	25	)	)	-RRB-
cord-298458-p7rvupjo	45	26	(	(	-LRB-
cord-298458-p7rvupjo	45	27	35	35	CD
cord-298458-p7rvupjo	45	28	)	)	-RRB-
cord-298458-p7rvupjo	45	29	(	(	-LRB-
cord-298458-p7rvupjo	45	30	36	36	CD
cord-298458-p7rvupjo	45	31	)	)	-RRB-
cord-298458-p7rvupjo	45	32	(	(	-LRB-
cord-298458-p7rvupjo	45	33	37	37	CD
cord-298458-p7rvupjo	45	34	)	)	-RRB-
cord-298458-p7rvupjo	45	35	.	.	.
cord-298458-p7rvupjo	46	1	The	the	DT
cord-298458-p7rvupjo	46	2	kinetics	kinetic	NNS
cord-298458-p7rvupjo	46	3	of	of	IN
cord-298458-p7rvupjo	46	4	virus	virus	NN
cord-298458-p7rvupjo	46	5	-	-	HYPH
cord-298458-p7rvupjo	46	6	specific	specific	JJ
cord-298458-p7rvupjo	46	7	CD8	CD8	NNP
cord-298458-p7rvupjo	46	8	T	T	NNP
cord-298458-p7rvupjo	46	9	cells	cell	NNS
cord-298458-p7rvupjo	46	10	are	be	VBP
cord-298458-p7rvupjo	46	11	slightly	slightly	RB
cord-298458-p7rvupjo	46	12	more	more	RBR
cord-298458-p7rvupjo	46	13	delayed	delay	VBN
cord-298458-p7rvupjo	46	14	following	follow	VBG
cord-298458-p7rvupjo	46	15	other	other	JJ
cord-298458-p7rvupjo	46	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	46	17	virus	virus	NN
cord-298458-p7rvupjo	46	18	infections	infection	NNS
cord-298458-p7rvupjo	46	19	with	with	IN
cord-298458-p7rvupjo	46	20	peaks	peak	NNS
cord-298458-p7rvupjo	46	21	occurring	occur	VBG
cord-298458-p7rvupjo	46	22	at	at	IN
cord-298458-p7rvupjo	46	23	approximately	approximately	RB
cord-298458-p7rvupjo	46	24	day	day	NN
cord-298458-p7rvupjo	46	25	10	10	CD
cord-298458-p7rvupjo	46	26	for	for	IN
cord-298458-p7rvupjo	46	27	IAV	IAV	NNP
cord-298458-p7rvupjo	46	28	,	,	,
cord-298458-p7rvupjo	46	29	days	day	NNS
cord-298458-p7rvupjo	46	30	10	10	CD
cord-298458-p7rvupjo	46	31	-	-	SYM
cord-298458-p7rvupjo	46	32	14	14	CD
cord-298458-p7rvupjo	46	33	for	for	IN
cord-298458-p7rvupjo	46	34	HMPV	HMPV	NNP
cord-298458-p7rvupjo	46	35	,	,	,
cord-298458-p7rvupjo	46	36	and	and	CC
cord-298458-p7rvupjo	46	37	days	day	NNS
cord-298458-p7rvupjo	46	38	12	12	CD
cord-298458-p7rvupjo	46	39	-	-	SYM
cord-298458-p7rvupjo	46	40	14	14	CD
cord-298458-p7rvupjo	46	41	for	for	IN
cord-298458-p7rvupjo	46	42	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	46	43	virus	virus	NN
cord-298458-p7rvupjo	46	44	of	of	IN
cord-298458-p7rvupjo	46	45	mice	mouse	NNS
cord-298458-p7rvupjo	46	46	(	(	-LRB-
cord-298458-p7rvupjo	46	47	PVM	PVM	NNP
cord-298458-p7rvupjo	46	48	)	)	-RRB-
cord-298458-p7rvupjo	46	49	,	,	,
cord-298458-p7rvupjo	46	50	a	a	DT
cord-298458-p7rvupjo	46	51	model	model	NN
cord-298458-p7rvupjo	46	52	respiratory	respiratory	JJ
cord-298458-p7rvupjo	46	53	virus	virus	NN
cord-298458-p7rvupjo	46	54	(	(	-LRB-
cord-298458-p7rvupjo	46	55	38	38	CD
cord-298458-p7rvupjo	46	56	)	)	-RRB-
cord-298458-p7rvupjo	46	57	(	(	-LRB-
cord-298458-p7rvupjo	46	58	39	39	CD
cord-298458-p7rvupjo	46	59	)	)	-RRB-
cord-298458-p7rvupjo	46	60	(	(	-LRB-
cord-298458-p7rvupjo	46	61	40	40	CD
cord-298458-p7rvupjo	46	62	)	)	-RRB-
cord-298458-p7rvupjo	46	63	(	(	-LRB-
cord-298458-p7rvupjo	46	64	41	41	CD
cord-298458-p7rvupjo	46	65	)	)	-RRB-
cord-298458-p7rvupjo	46	66	(	(	-LRB-
cord-298458-p7rvupjo	46	67	42	42	CD
cord-298458-p7rvupjo	46	68	)	)	-RRB-
cord-298458-p7rvupjo	46	69	.	.	.
cord-298458-p7rvupjo	47	1	The	the	DT
cord-298458-p7rvupjo	47	2	peak	peak	NN
cord-298458-p7rvupjo	47	3	of	of	IN
cord-298458-p7rvupjo	47	4	the	the	DT
cord-298458-p7rvupjo	47	5	antigen	antigen	NN
cord-298458-p7rvupjo	47	6	-	-	HYPH
cord-298458-p7rvupjo	47	7	specific	specific	JJ
cord-298458-p7rvupjo	47	8	CD8	CD8	NNP
cord-298458-p7rvupjo	47	9	T	T	NNP
cord-298458-p7rvupjo	47	10	cell	cell	NN
cord-298458-p7rvupjo	47	11	response	response	NN
cord-298458-p7rvupjo	47	12	generally	generally	RB
cord-298458-p7rvupjo	47	13	corresponds	correspond	VBZ
cord-298458-p7rvupjo	47	14	to	to	IN
cord-298458-p7rvupjo	47	15	lung	lung	NN
cord-298458-p7rvupjo	47	16	viral	viral	JJ
cord-298458-p7rvupjo	47	17	clearance	clearance	NN
cord-298458-p7rvupjo	47	18	following	follow	VBG
cord-298458-p7rvupjo	47	19	RSV	RSV	NNP
cord-298458-p7rvupjo	47	20	,	,	,
cord-298458-p7rvupjo	47	21	IAV	IAV	NNP
cord-298458-p7rvupjo	47	22	,	,	,
cord-298458-p7rvupjo	47	23	HMPV	HMPV	NNP
cord-298458-p7rvupjo	47	24	,	,	,
cord-298458-p7rvupjo	47	25	and	and	CC
cord-298458-p7rvupjo	47	26	PVM	PVM	NNP
cord-298458-p7rvupjo	47	27	infections	infection	NNS
cord-298458-p7rvupjo	47	28	(	(	-LRB-
cord-298458-p7rvupjo	47	29	36	36	CD
cord-298458-p7rvupjo	47	30	,	,	,
cord-298458-p7rvupjo	47	31	(	(	-LRB-
cord-298458-p7rvupjo	47	32	40	40	CD
cord-298458-p7rvupjo	47	33	)	)	-RRB-
cord-298458-p7rvupjo	47	34	(	(	-LRB-
cord-298458-p7rvupjo	47	35	41	41	CD
cord-298458-p7rvupjo	47	36	)	)	-RRB-
cord-298458-p7rvupjo	47	37	(	(	-LRB-
cord-298458-p7rvupjo	47	38	42	42	CD
cord-298458-p7rvupjo	47	39	)	)	-RRB-
cord-298458-p7rvupjo	47	40	(	(	-LRB-
cord-298458-p7rvupjo	47	41	43	43	CD
cord-298458-p7rvupjo	47	42	)	)	-RRB-
cord-298458-p7rvupjo	47	43	.	.	.
cord-298458-p7rvupjo	48	1	Human	human	JJ
cord-298458-p7rvupjo	48	2	CD8	CD8	NNP
cord-298458-p7rvupjo	48	3	T	T	NNP
cord-298458-p7rvupjo	48	4	cell	cell	NN
cord-298458-p7rvupjo	48	5	kinetics	kinetics	NN
cord-298458-p7rvupjo	48	6	following	follow	VBG
cord-298458-p7rvupjo	48	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	48	8	virus	virus	NN
cord-298458-p7rvupjo	48	9	infections	infection	NNS
cord-298458-p7rvupjo	48	10	are	be	VBP
cord-298458-p7rvupjo	48	11	less	less	RBR
cord-298458-p7rvupjo	48	12	well	well	RB
cord-298458-p7rvupjo	48	13	known	know	VBN
cord-298458-p7rvupjo	48	14	given	give	VBN
cord-298458-p7rvupjo	48	15	the	the	DT
cord-298458-p7rvupjo	48	16	lack	lack	NN
cord-298458-p7rvupjo	48	17	of	of	IN
cord-298458-p7rvupjo	48	18	identified	identify	VBN
cord-298458-p7rvupjo	48	19	CD8	CD8	NNP
cord-298458-p7rvupjo	48	20	T	T	NNP
cord-298458-p7rvupjo	48	21	cell	cell	NN
cord-298458-p7rvupjo	48	22	epitopes	epitope	NNS
cord-298458-p7rvupjo	48	23	and	and	CC
cord-298458-p7rvupjo	48	24	the	the	DT
cord-298458-p7rvupjo	48	25	difficulty	difficulty	NN
cord-298458-p7rvupjo	48	26	in	in	IN
cord-298458-p7rvupjo	48	27	obtaining	obtain	VBG
cord-298458-p7rvupjo	48	28	respiratory	respiratory	JJ
cord-298458-p7rvupjo	48	29	tract	tract	NN
cord-298458-p7rvupjo	48	30	samples	sample	NNS
cord-298458-p7rvupjo	48	31	from	from	IN
cord-298458-p7rvupjo	48	32	children	child	NNS
cord-298458-p7rvupjo	48	33	following	follow	VBG
cord-298458-p7rvupjo	48	34	initial	initial	JJ
cord-298458-p7rvupjo	48	35	virus	virus	NN
cord-298458-p7rvupjo	48	36	exposure	exposure	NN
cord-298458-p7rvupjo	48	37	.	.	.
cord-298458-p7rvupjo	49	1	The	the	DT
cord-298458-p7rvupjo	49	2	frequency	frequency	NN
cord-298458-p7rvupjo	49	3	of	of	IN
cord-298458-p7rvupjo	49	4	total	total	JJ
cord-298458-p7rvupjo	49	5	activated	activate	VBN
cord-298458-p7rvupjo	49	6	CD8	CD8	NNP
cord-298458-p7rvupjo	49	7	T	T	NNP
cord-298458-p7rvupjo	49	8	cells	cell	NNS
cord-298458-p7rvupjo	49	9	in	in	IN
cord-298458-p7rvupjo	49	10	tracheal	tracheal	NN
cord-298458-p7rvupjo	49	11	aspirates	aspirate	NNS
cord-298458-p7rvupjo	49	12	peaked	peak	VBD
cord-298458-p7rvupjo	49	13	at	at	IN
cord-298458-p7rvupjo	49	14	approximately	approximately	RB
cord-298458-p7rvupjo	49	15	10	10	CD
cord-298458-p7rvupjo	49	16	days	day	NNS
cord-298458-p7rvupjo	49	17	after	after	IN
cord-298458-p7rvupjo	49	18	the	the	DT
cord-298458-p7rvupjo	49	19	onset	onset	NN
cord-298458-p7rvupjo	49	20	of	of	IN
cord-298458-p7rvupjo	49	21	symptoms	symptom	NNS
cord-298458-p7rvupjo	49	22	in	in	IN
cord-298458-p7rvupjo	49	23	children	child	NNS
cord-298458-p7rvupjo	49	24	with	with	IN
cord-298458-p7rvupjo	49	25	RSV	RSV	NNP
cord-298458-p7rvupjo	49	26	,	,	,
cord-298458-p7rvupjo	49	27	IAV	IAV	NNP
cord-298458-p7rvupjo	49	28	,	,	,
cord-298458-p7rvupjo	49	29	RV	RV	NNP
cord-298458-p7rvupjo	49	30	,	,	,
cord-298458-p7rvupjo	49	31	or	or	CC
cord-298458-p7rvupjo	49	32	CoV	cov	NN
cord-298458-p7rvupjo	49	33	infections	infection	NNS
cord-298458-p7rvupjo	49	34	(	(	-LRB-
cord-298458-p7rvupjo	49	35	44	44	CD
cord-298458-p7rvupjo	49	36	)	)	-RRB-
cord-298458-p7rvupjo	49	37	.	.	.
cord-298458-p7rvupjo	50	1	RSV	RSV	NNP
cord-298458-p7rvupjo	50	2	-	-	HYPH
cord-298458-p7rvupjo	50	3	specific	specific	JJ
cord-298458-p7rvupjo	50	4	CD8	CD8	NNP
cord-298458-p7rvupjo	50	5	T	T	NNP
cord-298458-p7rvupjo	50	6	cells	cell	NNS
cord-298458-p7rvupjo	50	7	were	be	VBD
cord-298458-p7rvupjo	50	8	detected	detect	VBN
cord-298458-p7rvupjo	50	9	in	in	IN
cord-298458-p7rvupjo	50	10	the	the	DT
cord-298458-p7rvupjo	50	11	tracheal	tracheal	NN
cord-298458-p7rvupjo	50	12	aspirates	aspirate	NNS
cord-298458-p7rvupjo	50	13	of	of	IN
cord-298458-p7rvupjo	50	14	children	child	NNS
cord-298458-p7rvupjo	50	15	;	;	:
cord-298458-p7rvupjo	50	16	however	however	RB
cord-298458-p7rvupjo	50	17	,	,	,
cord-298458-p7rvupjo	50	18	the	the	DT
cord-298458-p7rvupjo	50	19	evaluated	evaluate	VBN
cord-298458-p7rvupjo	50	20	epitopes	epitope	NNS
cord-298458-p7rvupjo	50	21	were	be	VBD
cord-298458-p7rvupjo	50	22	present	present	JJ
cord-298458-p7rvupjo	50	23	at	at	IN
cord-298458-p7rvupjo	50	24	very	very	RB
cord-298458-p7rvupjo	50	25	low	low	JJ
cord-298458-p7rvupjo	50	26	frequencies	frequency	NNS
cord-298458-p7rvupjo	50	27	,	,	,
cord-298458-p7rvupjo	50	28	comprising	comprise	VBG
cord-298458-p7rvupjo	50	29	up	up	RP
cord-298458-p7rvupjo	50	30	to	to	IN
cord-298458-p7rvupjo	50	31	only	only	RB
cord-298458-p7rvupjo	50	32	2	2	CD
cord-298458-p7rvupjo	50	33	%	%	NN
cord-298458-p7rvupjo	50	34	of	of	IN
cord-298458-p7rvupjo	50	35	the	the	DT
cord-298458-p7rvupjo	50	36	total	total	JJ
cord-298458-p7rvupjo	50	37	CD8	CD8	NNP
cord-298458-p7rvupjo	50	38	T	T	NNP
cord-298458-p7rvupjo	50	39	cell	cell	NN
cord-298458-p7rvupjo	50	40	response	response	NN
cord-298458-p7rvupjo	50	41	(	(	-LRB-
cord-298458-p7rvupjo	50	42	44	44	CD
cord-298458-p7rvupjo	50	43	)	)	-RRB-
cord-298458-p7rvupjo	50	44	.	.	.
cord-298458-p7rvupjo	51	1	Following	follow	VBG
cord-298458-p7rvupjo	51	2	peak	peak	NN
cord-298458-p7rvupjo	51	3	expansion	expansion	NN
cord-298458-p7rvupjo	51	4	,	,	,
cord-298458-p7rvupjo	51	5	CD8	CD8	NNP
cord-298458-p7rvupjo	51	6	T	T	NNP
cord-298458-p7rvupjo	51	7	cell	cell	NN
cord-298458-p7rvupjo	51	8	contraction	contraction	NN
cord-298458-p7rvupjo	51	9	occurs	occur	VBZ
cord-298458-p7rvupjo	51	10	and	and	CC
cord-298458-p7rvupjo	51	11	a	a	DT
cord-298458-p7rvupjo	51	12	memory	memory	NN
cord-298458-p7rvupjo	51	13	population	population	NN
cord-298458-p7rvupjo	51	14	of	of	IN
cord-298458-p7rvupjo	51	15	virus	virus	NN
cord-298458-p7rvupjo	51	16	-	-	HYPH
cord-298458-p7rvupjo	51	17	specific	specific	JJ
cord-298458-p7rvupjo	51	18	CD8	CD8	NNP
cord-298458-p7rvupjo	51	19	T	T	NNP
cord-298458-p7rvupjo	51	20	cells	cell	NNS
cord-298458-p7rvupjo	51	21	remains	remain	VBZ
cord-298458-p7rvupjo	51	22	within	within	IN
cord-298458-p7rvupjo	51	23	the	the	DT
cord-298458-p7rvupjo	51	24	lung	lung	NN
cord-298458-p7rvupjo	51	25	.	.	.
cord-298458-p7rvupjo	52	1	The	the	DT
cord-298458-p7rvupjo	52	2	majority	majority	NN
cord-298458-p7rvupjo	52	3	of	of	IN
cord-298458-p7rvupjo	52	4	virus	virus	NN
cord-298458-p7rvupjo	52	5	-	-	HYPH
cord-298458-p7rvupjo	52	6	specific	specific	JJ
cord-298458-p7rvupjo	52	7	CD8	CD8	NNP
cord-298458-p7rvupjo	52	8	T	T	NNP
cord-298458-p7rvupjo	52	9	cells	cell	NNS
cord-298458-p7rvupjo	52	10	are	be	VBP
cord-298458-p7rvupjo	52	11	located	locate	VBN
cord-298458-p7rvupjo	52	12	within	within	IN
cord-298458-p7rvupjo	52	13	the	the	DT
cord-298458-p7rvupjo	52	14	lung	lung	NN
cord-298458-p7rvupjo	52	15	parenchyma	parenchyma	NN
cord-298458-p7rvupjo	52	16	,	,	,
cord-298458-p7rvupjo	52	17	rather	rather	RB
cord-298458-p7rvupjo	52	18	than	than	IN
cord-298458-p7rvupjo	52	19	the	the	DT
cord-298458-p7rvupjo	52	20	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	52	21	vasculature	vasculature	NN
cord-298458-p7rvupjo	52	22	,	,	,
cord-298458-p7rvupjo	52	23	following	follow	VBG
cord-298458-p7rvupjo	52	24	localized	localized	JJ
cord-298458-p7rvupjo	52	25	respiratory	respiratory	JJ
cord-298458-p7rvupjo	52	26	infections	infection	NNS
cord-298458-p7rvupjo	52	27	in	in	IN
cord-298458-p7rvupjo	52	28	mice	mouse	NNS
cord-298458-p7rvupjo	52	29	(	(	-LRB-
cord-298458-p7rvupjo	52	30	37	37	CD
cord-298458-p7rvupjo	52	31	)	)	-RRB-
cord-298458-p7rvupjo	52	32	.	.	.
cord-298458-p7rvupjo	53	1	Similarly	similarly	RB
cord-298458-p7rvupjo	53	2	,	,	,
cord-298458-p7rvupjo	53	3	human	human	JJ
cord-298458-p7rvupjo	53	4	RSV	rsv	NN
cord-298458-p7rvupjo	53	5	-	-	:
cord-298458-p7rvupjo	53	6	and	and	CC
cord-298458-p7rvupjo	53	7	IAV	iav	NN
cord-298458-p7rvupjo	53	8	-	-	HYPH
cord-298458-p7rvupjo	53	9	specific	specific	JJ
cord-298458-p7rvupjo	53	10	CD8	CD8	NNP
cord-298458-p7rvupjo	53	11	T	T	NNP
cord-298458-p7rvupjo	53	12	cells	cell	NNS
cord-298458-p7rvupjo	53	13	were	be	VBD
cord-298458-p7rvupjo	53	14	enriched	enrich	VBN
cord-298458-p7rvupjo	53	15	within	within	IN
cord-298458-p7rvupjo	53	16	the	the	DT
cord-298458-p7rvupjo	53	17	lung	lung	NN
cord-298458-p7rvupjo	53	18	compared	compare	VBN
cord-298458-p7rvupjo	53	19	to	to	IN
cord-298458-p7rvupjo	53	20	the	the	DT
cord-298458-p7rvupjo	53	21	blood	blood	NN
cord-298458-p7rvupjo	53	22	(	(	-LRB-
cord-298458-p7rvupjo	53	23	45	45	CD
cord-298458-p7rvupjo	53	24	)	)	-RRB-
cord-298458-p7rvupjo	53	25	.	.	.
cord-298458-p7rvupjo	54	1	RSV	RSV	NNP
cord-298458-p7rvupjo	54	2	-	-	HYPH
cord-298458-p7rvupjo	54	3	specific	specific	JJ
cord-298458-p7rvupjo	54	4	CD8	CD8	NNP
cord-298458-p7rvupjo	54	5	T	T	NNP
cord-298458-p7rvupjo	54	6	cells	cell	NNS
cord-298458-p7rvupjo	54	7	in	in	IN
cord-298458-p7rvupjo	54	8	tracheal	tracheal	JJ
cord-298458-p7rvupjo	54	9	aspirates	aspirate	NNS
cord-298458-p7rvupjo	54	10	of	of	IN
cord-298458-p7rvupjo	54	11	children	child	NNS
cord-298458-p7rvupjo	54	12	remain	remain	VBP
cord-298458-p7rvupjo	54	13	elevated	elevated	JJ
cord-298458-p7rvupjo	54	14	during	during	IN
cord-298458-p7rvupjo	54	15	convalescence	convalescence	NN
cord-298458-p7rvupjo	54	16	following	follow	VBG
cord-298458-p7rvupjo	54	17	a	a	DT
cord-298458-p7rvupjo	54	18	severe	severe	JJ
cord-298458-p7rvupjo	54	19	RSV	RSV	NNP
cord-298458-p7rvupjo	54	20	infection	infection	NN
cord-298458-p7rvupjo	54	21	,	,	,
cord-298458-p7rvupjo	54	22	in	in	IN
cord-298458-p7rvupjo	54	23	contrast	contrast	NN
cord-298458-p7rvupjo	54	24	to	to	IN
cord-298458-p7rvupjo	54	25	murine	murine	JJ
cord-298458-p7rvupjo	54	26	studies	study	NNS
cord-298458-p7rvupjo	54	27	(	(	-LRB-
cord-298458-p7rvupjo	54	28	46	46	CD
cord-298458-p7rvupjo	54	29	)	)	-RRB-
cord-298458-p7rvupjo	54	30	.	.	.
cord-298458-p7rvupjo	55	1	These	these	DT
cord-298458-p7rvupjo	55	2	studies	study	NNS
cord-298458-p7rvupjo	55	3	suggest	suggest	VBP
cord-298458-p7rvupjo	55	4	that	that	IN
cord-298458-p7rvupjo	55	5	CD8	CD8	NNP
cord-298458-p7rvupjo	55	6	T	T	NNP
cord-298458-p7rvupjo	55	7	cell	cell	NN
cord-298458-p7rvupjo	55	8	responses	response	NNS
cord-298458-p7rvupjo	55	9	in	in	IN
cord-298458-p7rvupjo	55	10	the	the	DT
cord-298458-p7rvupjo	55	11	airways	airways	NNPS
cord-298458-p7rvupjo	55	12	may	may	MD
cord-298458-p7rvupjo	55	13	be	be	VB
cord-298458-p7rvupjo	55	14	more	more	RBR
cord-298458-p7rvupjo	55	15	prolonged	prolonged	JJ
cord-298458-p7rvupjo	55	16	following	follow	VBG
cord-298458-p7rvupjo	55	17	viral	viral	JJ
cord-298458-p7rvupjo	55	18	clearance	clearance	NN
cord-298458-p7rvupjo	55	19	in	in	IN
cord-298458-p7rvupjo	55	20	humans	human	NNS
cord-298458-p7rvupjo	55	21	compared	compare	VBN
cord-298458-p7rvupjo	55	22	to	to	IN
cord-298458-p7rvupjo	55	23	mice	mouse	NNS
cord-298458-p7rvupjo	55	24	.	.	.
cord-298458-p7rvupjo	56	1	Following	follow	VBG
cord-298458-p7rvupjo	56	2	respiratory	respiratory	JJ
cord-298458-p7rvupjo	56	3	virus	virus	NN
cord-298458-p7rvupjo	56	4	infection	infection	NN
cord-298458-p7rvupjo	56	5	,	,	,
cord-298458-p7rvupjo	56	6	CD8	CD8	NNP
cord-298458-p7rvupjo	56	7	T	T	NNP
cord-298458-p7rvupjo	56	8	cells	cell	NNS
cord-298458-p7rvupjo	56	9	become	become	VBP
cord-298458-p7rvupjo	56	10	activated	activate	VBN
cord-298458-p7rvupjo	56	11	and	and	CC
cord-298458-p7rvupjo	56	12	develop	develop	VB
cord-298458-p7rvupjo	56	13	the	the	DT
cord-298458-p7rvupjo	56	14	ability	ability	NN
cord-298458-p7rvupjo	56	15	to	to	TO
cord-298458-p7rvupjo	56	16	produce	produce	VB
cord-298458-p7rvupjo	56	17	inflammatory	inflammatory	JJ
cord-298458-p7rvupjo	56	18	cytokines	cytokine	NNS
cord-298458-p7rvupjo	56	19	.	.	.
cord-298458-p7rvupjo	57	1	Virus	virus	NN
cord-298458-p7rvupjo	57	2	-	-	HYPH
cord-298458-p7rvupjo	57	3	specific	specific	JJ
cord-298458-p7rvupjo	57	4	CD8	CD8	NNP
cord-298458-p7rvupjo	57	5	T	T	NNP
cord-298458-p7rvupjo	57	6	cells	cell	NNS
cord-298458-p7rvupjo	57	7	in	in	IN
cord-298458-p7rvupjo	57	8	the	the	DT
cord-298458-p7rvupjo	57	9	lung	lung	NN
cord-298458-p7rvupjo	57	10	and	and	CC
cord-298458-p7rvupjo	57	11	airways	airways	NNPS
cord-298458-p7rvupjo	57	12	of	of	IN
cord-298458-p7rvupjo	57	13	mice	mouse	NNS
cord-298458-p7rvupjo	57	14	upregulate	upregulate	VBP
cord-298458-p7rvupjo	57	15	expression	expression	NN
cord-298458-p7rvupjo	57	16	of	of	IN
cord-298458-p7rvupjo	57	17	markers	marker	NNS
cord-298458-p7rvupjo	57	18	associated	associate	VBN
cord-298458-p7rvupjo	57	19	with	with	IN
cord-298458-p7rvupjo	57	20	activation	activation	NN
cord-298458-p7rvupjo	57	21	including	include	VBG
cord-298458-p7rvupjo	57	22	CD11a	CD11a	NNS
cord-298458-p7rvupjo	57	23	,	,	,
cord-298458-p7rvupjo	57	24	CD25	CD25	NNP
cord-298458-p7rvupjo	57	25	,	,	,
cord-298458-p7rvupjo	57	26	NKG2a	NKG2a	NNP
cord-298458-p7rvupjo	57	27	,	,	,
cord-298458-p7rvupjo	57	28	and	and	CC
cord-298458-p7rvupjo	57	29	CD44	CD44	NNP
cord-298458-p7rvupjo	57	30	as	as	RB
cord-298458-p7rvupjo	57	31	well	well	RB
cord-298458-p7rvupjo	57	32	as	as	IN
cord-298458-p7rvupjo	57	33	downregulate	downregulate	JJ
cord-298458-p7rvupjo	57	34	expression	expression	NN
cord-298458-p7rvupjo	57	35	of	of	IN
cord-298458-p7rvupjo	57	36	the	the	DT
cord-298458-p7rvupjo	57	37	lymphoid	lymphoid	JJ
cord-298458-p7rvupjo	57	38	homing	homing	NN
cord-298458-p7rvupjo	57	39	receptor	receptor	NN
cord-298458-p7rvupjo	57	40	CD62L	cd62l	NN
cord-298458-p7rvupjo	58	1	(	(	-LRB-
cord-298458-p7rvupjo	58	2	34	34	CD
cord-298458-p7rvupjo	58	3	,	,	,
cord-298458-p7rvupjo	58	4	35	35	CD
cord-298458-p7rvupjo	58	5	,	,	,
cord-298458-p7rvupjo	58	6	47	47	CD
cord-298458-p7rvupjo	58	7	,	,	,
cord-298458-p7rvupjo	58	8	48	48	CD
cord-298458-p7rvupjo	58	9	)	)	-RRB-
cord-298458-p7rvupjo	58	10	.	.	.
cord-298458-p7rvupjo	59	1	Activated	Activated	NNP
cord-298458-p7rvupjo	59	2	CD8	CD8	NNP
cord-298458-p7rvupjo	59	3	T	T	NNP
cord-298458-p7rvupjo	59	4	cells	cell	NNS
cord-298458-p7rvupjo	59	5	also	also	RB
cord-298458-p7rvupjo	59	6	acquire	acquire	VBP
cord-298458-p7rvupjo	59	7	effector	effector	NN
cord-298458-p7rvupjo	59	8	functions	function	NNS
cord-298458-p7rvupjo	59	9	following	follow	VBG
cord-298458-p7rvupjo	59	10	viral	viral	JJ
cord-298458-p7rvupjo	59	11	infection	infection	NN
cord-298458-p7rvupjo	59	12	.	.	.
cord-298458-p7rvupjo	60	1	Virus	virus	NN
cord-298458-p7rvupjo	60	2	-	-	HYPH
cord-298458-p7rvupjo	60	3	specific	specific	JJ
cord-298458-p7rvupjo	60	4	CD8	CD8	NNP
cord-298458-p7rvupjo	60	5	T	T	NNP
cord-298458-p7rvupjo	60	6	cells	cell	NNS
cord-298458-p7rvupjo	60	7	rapidly	rapidly	RB
cord-298458-p7rvupjo	60	8	produce	produce	VBP
cord-298458-p7rvupjo	60	9	cytokines	cytokine	NNS
cord-298458-p7rvupjo	60	10	including	include	VBG
cord-298458-p7rvupjo	60	11	IFN	IFN	NNP
cord-298458-p7rvupjo	60	12	-	-	HYPH
cord-298458-p7rvupjo	60	13	γ	γ	NNP
cord-298458-p7rvupjo	60	14	and	and	CC
cord-298458-p7rvupjo	60	15	TNF	TNF	NNP
cord-298458-p7rvupjo	60	16	as	as	RB
cord-298458-p7rvupjo	60	17	well	well	RB
cord-298458-p7rvupjo	60	18	as	as	IN
cord-298458-p7rvupjo	60	19	degranulate	degranulate	NNP
cord-298458-p7rvupjo	60	20	,	,	,
cord-298458-p7rvupjo	60	21	as	as	IN
cord-298458-p7rvupjo	60	22	measured	measure	VBN
cord-298458-p7rvupjo	60	23	by	by	IN
cord-298458-p7rvupjo	60	24	CD107a	CD107a	NNP
cord-298458-p7rvupjo	60	25	expression	expression	NN
cord-298458-p7rvupjo	60	26	,	,	,
cord-298458-p7rvupjo	60	27	following	follow	VBG
cord-298458-p7rvupjo	60	28	ex	ex	FW
cord-298458-p7rvupjo	60	29	vivo	vivo	NN
cord-298458-p7rvupjo	60	30	peptide	peptide	JJ
cord-298458-p7rvupjo	60	31	stimulation	stimulation	NN
cord-298458-p7rvupjo	60	32	(	(	-LRB-
cord-298458-p7rvupjo	60	33	35	35	CD
cord-298458-p7rvupjo	60	34	,	,	,
cord-298458-p7rvupjo	60	35	38	38	CD
cord-298458-p7rvupjo	60	36	,	,	,
cord-298458-p7rvupjo	60	37	41	41	CD
cord-298458-p7rvupjo	60	38	,	,	,
cord-298458-p7rvupjo	60	39	48	48	CD
cord-298458-p7rvupjo	60	40	)	)	-RRB-
cord-298458-p7rvupjo	60	41	.	.	.
cord-298458-p7rvupjo	61	1	Human	human	JJ
cord-298458-p7rvupjo	61	2	virusspecific	virusspecific	NN
cord-298458-p7rvupjo	61	3	CD8	CD8	NNP
cord-298458-p7rvupjo	61	4	T	T	NNP
cord-298458-p7rvupjo	61	5	cells	cell	NNS
cord-298458-p7rvupjo	61	6	also	also	RB
cord-298458-p7rvupjo	61	7	acquire	acquire	VBP
cord-298458-p7rvupjo	61	8	an	an	DT
cord-298458-p7rvupjo	61	9	activated	activate	VBN
cord-298458-p7rvupjo	61	10	phenotype	phenotype	NN
cord-298458-p7rvupjo	61	11	and	and	CC
cord-298458-p7rvupjo	61	12	effector	effector	NN
cord-298458-p7rvupjo	61	13	functions	function	NNS
cord-298458-p7rvupjo	61	14	following	follow	VBG
cord-298458-p7rvupjo	61	15	a	a	DT
cord-298458-p7rvupjo	61	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	61	17	virus	virus	NN
cord-298458-p7rvupjo	61	18	infection	infection	NN
cord-298458-p7rvupjo	61	19	.	.	.
cord-298458-p7rvupjo	62	1	CD8	CD8	NNP
cord-298458-p7rvupjo	62	2	T	T	NNP
cord-298458-p7rvupjo	62	3	cells	cell	NNS
cord-298458-p7rvupjo	62	4	from	from	IN
cord-298458-p7rvupjo	62	5	the	the	DT
cord-298458-p7rvupjo	62	6	tracheal	tracheal	NN
cord-298458-p7rvupjo	62	7	aspirates	aspirate	NNS
cord-298458-p7rvupjo	62	8	of	of	IN
cord-298458-p7rvupjo	62	9	children	child	NNS
cord-298458-p7rvupjo	62	10	following	follow	VBG
cord-298458-p7rvupjo	62	11	RSV	RSV	NNP
cord-298458-p7rvupjo	62	12	,	,	,
cord-298458-p7rvupjo	62	13	RV	RV	NNP
cord-298458-p7rvupjo	62	14	,	,	,
cord-298458-p7rvupjo	62	15	or	or	CC
cord-298458-p7rvupjo	62	16	CoV	cov	NN
cord-298458-p7rvupjo	62	17	infections	infection	NNS
cord-298458-p7rvupjo	62	18	expressed	express	VBD
cord-298458-p7rvupjo	62	19	elevated	elevated	JJ
cord-298458-p7rvupjo	62	20	levels	level	NNS
cord-298458-p7rvupjo	62	21	of	of	IN
cord-298458-p7rvupjo	62	22	the	the	DT
cord-298458-p7rvupjo	62	23	activation	activation	NN
cord-298458-p7rvupjo	62	24	markers	marker	NNS
cord-298458-p7rvupjo	62	25	CD38	CD38	NNP
cord-298458-p7rvupjo	62	26	and	and	CC
cord-298458-p7rvupjo	62	27	HLA	HLA	NNP
cord-298458-p7rvupjo	62	28	-	-	HYPH
cord-298458-p7rvupjo	62	29	DR	DR	NNP
cord-298458-p7rvupjo	62	30	and	and	CC
cord-298458-p7rvupjo	62	31	the	the	DT
cord-298458-p7rvupjo	62	32	proliferation	proliferation	NN
cord-298458-p7rvupjo	62	33	marker	marker	NN
cord-298458-p7rvupjo	63	1	Ki-67	Ki-67	.
cord-298458-p7rvupjo	64	1	(	(	-LRB-
cord-298458-p7rvupjo	64	2	44	44	CD
cord-298458-p7rvupjo	64	3	)	)	-RRB-
cord-298458-p7rvupjo	64	4	.	.	.
cord-298458-p7rvupjo	65	1	Expression	expression	NN
cord-298458-p7rvupjo	65	2	of	of	IN
cord-298458-p7rvupjo	65	3	effector	effector	NN
cord-298458-p7rvupjo	65	4	molecules	molecule	NNS
cord-298458-p7rvupjo	65	5	such	such	JJ
cord-298458-p7rvupjo	65	6	as	as	IN
cord-298458-p7rvupjo	65	7	granzyme	granzyme	NNP
cord-298458-p7rvupjo	65	8	B	B	NNP
cord-298458-p7rvupjo	65	9	and	and	CC
cord-298458-p7rvupjo	65	10	perforin	perforin	NNP
cord-298458-p7rvupjo	65	11	were	be	VBD
cord-298458-p7rvupjo	65	12	also	also	RB
cord-298458-p7rvupjo	65	13	increased	increase	VBN
cord-298458-p7rvupjo	65	14	.	.	.
cord-298458-p7rvupjo	66	1	Similarly	similarly	RB
cord-298458-p7rvupjo	66	2	,	,	,
cord-298458-p7rvupjo	66	3	CD8	CD8	NNP
cord-298458-p7rvupjo	66	4	T	T	NNP
cord-298458-p7rvupjo	66	5	cells	cell	NNS
cord-298458-p7rvupjo	66	6	from	from	IN
cord-298458-p7rvupjo	66	7	bronchiolar	bronchiolar	JJ
cord-298458-p7rvupjo	66	8	lavage	lavage	NN
cord-298458-p7rvupjo	66	9	(	(	-LRB-
cord-298458-p7rvupjo	66	10	BAL	BAL	NNP
cord-298458-p7rvupjo	66	11	)	)	-RRB-
cord-298458-p7rvupjo	66	12	fluid	fluid	JJ
cord-298458-p7rvupjo	66	13	samples	sample	NNS
cord-298458-p7rvupjo	66	14	exhibited	exhibit	VBD
cord-298458-p7rvupjo	66	15	increased	increased	JJ
cord-298458-p7rvupjo	66	16	expression	expression	NN
cord-298458-p7rvupjo	66	17	of	of	IN
cord-298458-p7rvupjo	66	18	Ki-67	Ki-67	NNP
cord-298458-p7rvupjo	66	19	,	,	,
cord-298458-p7rvupjo	66	20	granzyme	granzyme	NNS
cord-298458-p7rvupjo	66	21	B	B	NNP
cord-298458-p7rvupjo	66	22	,	,	,
cord-298458-p7rvupjo	66	23	CD38	CD38	NNP
cord-298458-p7rvupjo	66	24	,	,	,
cord-298458-p7rvupjo	66	25	and	and	CC
cord-298458-p7rvupjo	66	26	HLA	HLA	NNP
cord-298458-p7rvupjo	66	27	-	-	HYPH
cord-298458-p7rvupjo	66	28	DR	DR	NNP
cord-298458-p7rvupjo	66	29	following	follow	VBG
cord-298458-p7rvupjo	66	30	either	either	CC
cord-298458-p7rvupjo	66	31	experimental	experimental	JJ
cord-298458-p7rvupjo	66	32	RSV	rsv	NN
cord-298458-p7rvupjo	66	33	infection	infection	NN
cord-298458-p7rvupjo	66	34	of	of	IN
cord-298458-p7rvupjo	66	35	adults	adult	NNS
cord-298458-p7rvupjo	66	36	or	or	CC
cord-298458-p7rvupjo	66	37	severe	severe	JJ
cord-298458-p7rvupjo	66	38	,	,	,
cord-298458-p7rvupjo	66	39	natural	natural	JJ
cord-298458-p7rvupjo	66	40	RSV	RSV	NNP
cord-298458-p7rvupjo	66	41	infection	infection	NN
cord-298458-p7rvupjo	66	42	of	of	IN
cord-298458-p7rvupjo	66	43	infants	infant	NNS
cord-298458-p7rvupjo	66	44	(	(	-LRB-
cord-298458-p7rvupjo	66	45	46	46	CD
cord-298458-p7rvupjo	66	46	,	,	,
cord-298458-p7rvupjo	66	47	49	49	CD
cord-298458-p7rvupjo	66	48	)	)	-RRB-
cord-298458-p7rvupjo	66	49	.	.	.
cord-298458-p7rvupjo	67	1	Additionally	additionally	RB
cord-298458-p7rvupjo	67	2	,	,	,
cord-298458-p7rvupjo	67	3	human	human	JJ
cord-298458-p7rvupjo	67	4	virusspecific	virusspecific	NN
cord-298458-p7rvupjo	67	5	CD8	CD8	NNP
cord-298458-p7rvupjo	67	6	T	T	NNP
cord-298458-p7rvupjo	67	7	cells	cell	NNS
cord-298458-p7rvupjo	67	8	produce	produce	VBP
cord-298458-p7rvupjo	67	9	cytokines	cytokine	NNS
cord-298458-p7rvupjo	67	10	following	follow	VBG
cord-298458-p7rvupjo	67	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	67	12	virus	virus	NN
cord-298458-p7rvupjo	67	13	infection	infection	NN
cord-298458-p7rvupjo	67	14	,	,	,
cord-298458-p7rvupjo	67	15	as	as	IN
cord-298458-p7rvupjo	67	16	peripheral	peripheral	JJ
cord-298458-p7rvupjo	67	17	blood	blood	NN
cord-298458-p7rvupjo	67	18	CD8	CD8	NNP
cord-298458-p7rvupjo	67	19	T	T	NNP
cord-298458-p7rvupjo	67	20	cells	cell	NNS
cord-298458-p7rvupjo	67	21	secreted	secrete	VBD
cord-298458-p7rvupjo	67	22	IFN	IFN	NNP
cord-298458-p7rvupjo	67	23	-	-	HYPH
cord-298458-p7rvupjo	67	24	γ	γ	NNP
cord-298458-p7rvupjo	67	25	,	,	,
cord-298458-p7rvupjo	67	26	TNF	TNF	NNP
cord-298458-p7rvupjo	67	27	,	,	,
cord-298458-p7rvupjo	67	28	and	and	CC
cord-298458-p7rvupjo	67	29	IL-2	il-2	NN
cord-298458-p7rvupjo	67	30	following	follow	VBG
cord-298458-p7rvupjo	67	31	stimulation	stimulation	NN
cord-298458-p7rvupjo	67	32	with	with	IN
cord-298458-p7rvupjo	67	33	peptides	peptide	NNS
cord-298458-p7rvupjo	67	34	derived	derive	VBN
cord-298458-p7rvupjo	67	35	from	from	IN
cord-298458-p7rvupjo	67	36	RSV	RSV	NNP
cord-298458-p7rvupjo	67	37	,	,	,
cord-298458-p7rvupjo	67	38	IAV	IAV	NNP
cord-298458-p7rvupjo	67	39	,	,	,
cord-298458-p7rvupjo	67	40	HMPV	HMPV	NNP
cord-298458-p7rvupjo	67	41	,	,	,
cord-298458-p7rvupjo	67	42	or	or	CC
cord-298458-p7rvupjo	67	43	RV	rv	NN
cord-298458-p7rvupjo	67	44	(	(	-LRB-
cord-298458-p7rvupjo	67	45	49	49	CD
cord-298458-p7rvupjo	67	46	-	-	SYM
cord-298458-p7rvupjo	67	47	53	53	CD
cord-298458-p7rvupjo	67	48	)	)	-RRB-
cord-298458-p7rvupjo	67	49	.	.	.
cord-298458-p7rvupjo	68	1	Following	follow	VBG
cord-298458-p7rvupjo	68	2	contraction	contraction	NN
cord-298458-p7rvupjo	68	3	,	,	,
cord-298458-p7rvupjo	68	4	a	a	DT
cord-298458-p7rvupjo	68	5	subset	subset	NN
cord-298458-p7rvupjo	68	6	of	of	IN
cord-298458-p7rvupjo	68	7	virus	virus	NN
cord-298458-p7rvupjo	68	8	-	-	HYPH
cord-298458-p7rvupjo	68	9	specific	specific	JJ
cord-298458-p7rvupjo	68	10	CD8	CD8	NNP
cord-298458-p7rvupjo	68	11	T	T	NNP
cord-298458-p7rvupjo	68	12	cells	cell	NNS
cord-298458-p7rvupjo	68	13	remain	remain	VBP
cord-298458-p7rvupjo	68	14	in	in	IN
cord-298458-p7rvupjo	68	15	the	the	DT
cord-298458-p7rvupjo	68	16	host	host	NN
cord-298458-p7rvupjo	68	17	to	to	TO
cord-298458-p7rvupjo	68	18	form	form	VB
cord-298458-p7rvupjo	68	19	a	a	DT
cord-298458-p7rvupjo	68	20	long	long	RB
cord-298458-p7rvupjo	68	21	-	-	HYPH
cord-298458-p7rvupjo	68	22	lasting	last	VBG
cord-298458-p7rvupjo	68	23	memory	memory	NN
cord-298458-p7rvupjo	68	24	population	population	NN
cord-298458-p7rvupjo	68	25	that	that	WDT
cord-298458-p7rvupjo	68	26	provides	provide	VBZ
cord-298458-p7rvupjo	68	27	protection	protection	NN
cord-298458-p7rvupjo	68	28	against	against	IN
cord-298458-p7rvupjo	68	29	subsequent	subsequent	JJ
cord-298458-p7rvupjo	68	30	infection	infection	NN
cord-298458-p7rvupjo	68	31	.	.	.
cord-298458-p7rvupjo	69	1	CD8	CD8	NNP
cord-298458-p7rvupjo	69	2	T	T	NNP
cord-298458-p7rvupjo	69	3	cell	cell	NN
cord-298458-p7rvupjo	69	4	contraction	contraction	NN
cord-298458-p7rvupjo	69	5	to	to	TO
cord-298458-p7rvupjo	69	6	form	form	VB
cord-298458-p7rvupjo	69	7	long	long	JJ
cord-298458-p7rvupjo	69	8	-	-	HYPH
cord-298458-p7rvupjo	69	9	term	term	NN
cord-298458-p7rvupjo	69	10	memory	memory	NN
cord-298458-p7rvupjo	69	11	populations	population	NNS
cord-298458-p7rvupjo	69	12	in	in	IN
cord-298458-p7rvupjo	69	13	the	the	DT
cord-298458-p7rvupjo	69	14	lung	lung	NN
cord-298458-p7rvupjo	69	15	is	be	VBZ
cord-298458-p7rvupjo	69	16	regulated	regulate	VBN
cord-298458-p7rvupjo	69	17	in	in	IN
cord-298458-p7rvupjo	69	18	part	part	NN
cord-298458-p7rvupjo	69	19	by	by	IN
cord-298458-p7rvupjo	69	20	inflammatory	inflammatory	JJ
cord-298458-p7rvupjo	69	21	chemokine	chemokine	NN
cord-298458-p7rvupjo	69	22	signaling	signaling	NN
cord-298458-p7rvupjo	69	23	(	(	-LRB-
cord-298458-p7rvupjo	69	24	54	54	CD
cord-298458-p7rvupjo	69	25	)	)	-RRB-
cord-298458-p7rvupjo	69	26	.	.	.
cord-298458-p7rvupjo	70	1	Mice	mouse	NNS
cord-298458-p7rvupjo	70	2	deficient	deficient	JJ
cord-298458-p7rvupjo	70	3	in	in	IN
cord-298458-p7rvupjo	70	4	either	either	CC
cord-298458-p7rvupjo	70	5	CXCR3	cxcr3	NN
cord-298458-p7rvupjo	70	6	or	or	CC
cord-298458-p7rvupjo	70	7	CXCR3	CXCR3	NNP
cord-298458-p7rvupjo	70	8	and	and	CC
cord-298458-p7rvupjo	70	9	CCR5	CCR5	NNP
cord-298458-p7rvupjo	70	10	exhibit	exhibit	VBP
cord-298458-p7rvupjo	70	11	a	a	DT
cord-298458-p7rvupjo	70	12	significant	significant	JJ
cord-298458-p7rvupjo	70	13	increase	increase	NN
cord-298458-p7rvupjo	70	14	in	in	IN
cord-298458-p7rvupjo	70	15	the	the	DT
cord-298458-p7rvupjo	70	16	number	number	NN
cord-298458-p7rvupjo	70	17	of	of	IN
cord-298458-p7rvupjo	70	18	memory	memory	NN
cord-298458-p7rvupjo	70	19	CD8	CD8	NNP
cord-298458-p7rvupjo	70	20	T	T	NNP
cord-298458-p7rvupjo	70	21	cells	cell	NNS
cord-298458-p7rvupjo	70	22	following	follow	VBG
cord-298458-p7rvupjo	70	23	IAV	IAV	NNP
cord-298458-p7rvupjo	70	24	infection	infection	NN
cord-298458-p7rvupjo	70	25	,	,	,
cord-298458-p7rvupjo	70	26	suggesting	suggest	VBG
cord-298458-p7rvupjo	70	27	that	that	IN
cord-298458-p7rvupjo	70	28	chemokine	chemokine	NN
cord-298458-p7rvupjo	70	29	signaling	signal	VBG
cord-298458-p7rvupjo	70	30	through	through	IN
cord-298458-p7rvupjo	70	31	CXCR3	cxcr3	NN
cord-298458-p7rvupjo	70	32	and	and	CC
cord-298458-p7rvupjo	70	33	CCR5	CCR5	NNP
cord-298458-p7rvupjo	70	34	plays	play	VBZ
cord-298458-p7rvupjo	70	35	a	a	DT
cord-298458-p7rvupjo	70	36	critical	critical	JJ
cord-298458-p7rvupjo	70	37	role	role	NN
cord-298458-p7rvupjo	70	38	in	in	IN
cord-298458-p7rvupjo	70	39	T	T	NNP
cord-298458-p7rvupjo	70	40	cell	cell	NN
cord-298458-p7rvupjo	70	41	memory	memory	NN
cord-298458-p7rvupjo	70	42	generation	generation	NN
cord-298458-p7rvupjo	70	43	(	(	-LRB-
cord-298458-p7rvupjo	70	44	54	54	CD
cord-298458-p7rvupjo	70	45	)	)	-RRB-
cord-298458-p7rvupjo	70	46	.	.	.
cord-298458-p7rvupjo	71	1	Following	follow	VBG
cord-298458-p7rvupjo	71	2	respiratory	respiratory	JJ
cord-298458-p7rvupjo	71	3	viral	viral	JJ
cord-298458-p7rvupjo	71	4	infections	infection	NNS
cord-298458-p7rvupjo	71	5	in	in	IN
cord-298458-p7rvupjo	71	6	mice	mouse	NNS
cord-298458-p7rvupjo	71	7	and	and	CC
cord-298458-p7rvupjo	71	8	humans	human	NNS
cord-298458-p7rvupjo	71	9	,	,	,
cord-298458-p7rvupjo	71	10	virus	virus	NN
cord-298458-p7rvupjo	71	11	-	-	HYPH
cord-298458-p7rvupjo	71	12	specific	specific	JJ
cord-298458-p7rvupjo	71	13	CD8	CD8	NNP
cord-298458-p7rvupjo	71	14	T	T	NNP
cord-298458-p7rvupjo	71	15	cells	cell	NNS
cord-298458-p7rvupjo	71	16	can	can	MD
cord-298458-p7rvupjo	71	17	be	be	VB
cord-298458-p7rvupjo	71	18	detected	detect	VBN
cord-298458-p7rvupjo	71	19	up	up	RP
cord-298458-p7rvupjo	71	20	to	to	IN
cord-298458-p7rvupjo	71	21	several	several	JJ
cord-298458-p7rvupjo	71	22	months	month	NNS
cord-298458-p7rvupjo	71	23	post	post	NN
cord-298458-p7rvupjo	71	24	-	-	NN
cord-298458-p7rvupjo	71	25	infection	infection	NN
cord-298458-p7rvupjo	71	26	(	(	-LRB-
cord-298458-p7rvupjo	71	27	47	47	CD
cord-298458-p7rvupjo	71	28	,	,	,
cord-298458-p7rvupjo	71	29	49	49	CD
cord-298458-p7rvupjo	71	30	,	,	,
cord-298458-p7rvupjo	71	31	55	55	CD
cord-298458-p7rvupjo	71	32	,	,	,
cord-298458-p7rvupjo	71	33	56	56	CD
cord-298458-p7rvupjo	71	34	)	)	-RRB-
cord-298458-p7rvupjo	71	35	.	.	.
cord-298458-p7rvupjo	72	1	However	however	RB
cord-298458-p7rvupjo	72	2	,	,	,
cord-298458-p7rvupjo	72	3	respiratory	respiratory	JJ
cord-298458-p7rvupjo	72	4	virus	virus	NN
cord-298458-p7rvupjo	72	5	-	-	HYPH
cord-298458-p7rvupjo	72	6	specific	specific	JJ
cord-298458-p7rvupjo	72	7	memory	memory	NN
cord-298458-p7rvupjo	72	8	CD8	CD8	NNP
cord-298458-p7rvupjo	72	9	T	T	NNP
cord-298458-p7rvupjo	72	10	cell	cell	NN
cord-298458-p7rvupjo	72	11	populations	population	NNS
cord-298458-p7rvupjo	72	12	decline	decline	VBP
cord-298458-p7rvupjo	72	13	in	in	IN
cord-298458-p7rvupjo	72	14	magnitude	magnitude	NN
cord-298458-p7rvupjo	72	15	with	with	IN
cord-298458-p7rvupjo	72	16	age	age	NN
cord-298458-p7rvupjo	72	17	in	in	IN
cord-298458-p7rvupjo	72	18	the	the	DT
cord-298458-p7rvupjo	72	19	peripheral	peripheral	JJ
cord-298458-p7rvupjo	72	20	blood	blood	NN
cord-298458-p7rvupjo	72	21	(	(	-LRB-
cord-298458-p7rvupjo	72	22	57	57	CD
cord-298458-p7rvupjo	72	23	)	)	-RRB-
cord-298458-p7rvupjo	72	24	.	.	.
cord-298458-p7rvupjo	73	1	Interestingly	interestingly	RB
cord-298458-p7rvupjo	73	2	,	,	,
cord-298458-p7rvupjo	73	3	adult	adult	NN
cord-298458-p7rvupjo	73	4	RSV	rsv	NN
cord-298458-p7rvupjo	73	5	-	-	HYPH
cord-298458-p7rvupjo	73	6	specific	specific	JJ
cord-298458-p7rvupjo	73	7	CD8	CD8	NNP
cord-298458-p7rvupjo	73	8	T	t	IN
cord-298458-p7rvupjo	73	9	cell	cell	NN
cord-298458-p7rvupjo	73	10	responses	response	NNS
cord-298458-p7rvupjo	73	11	are	be	VBP
cord-298458-p7rvupjo	73	12	significantly	significantly	RB
cord-298458-p7rvupjo	73	13	reduced	reduce	VBN
cord-298458-p7rvupjo	73	14	compared	compare	VBN
cord-298458-p7rvupjo	73	15	to	to	IN
cord-298458-p7rvupjo	73	16	IAV	iav	NN
cord-298458-p7rvupjo	73	17	-	-	HYPH
cord-298458-p7rvupjo	73	18	specific	specific	JJ
cord-298458-p7rvupjo	73	19	CD8	CD8	NNP
cord-298458-p7rvupjo	73	20	T	T	NNP
cord-298458-p7rvupjo	73	21	cell	cell	NN
cord-298458-p7rvupjo	73	22	responses	response	NNS
cord-298458-p7rvupjo	73	23	in	in	IN
cord-298458-p7rvupjo	73	24	the	the	DT
cord-298458-p7rvupjo	73	25	peripheral	peripheral	JJ
cord-298458-p7rvupjo	73	26	blood	blood	NN
cord-298458-p7rvupjo	73	27	,	,	,
cord-298458-p7rvupjo	73	28	suggesting	suggest	VBG
cord-298458-p7rvupjo	73	29	that	that	IN
cord-298458-p7rvupjo	73	30	memory	memory	NN
cord-298458-p7rvupjo	73	31	CD8	CD8	NNP
cord-298458-p7rvupjo	73	32	T	T	NNP
cord-298458-p7rvupjo	73	33	cell	cell	NN
cord-298458-p7rvupjo	73	34	responses	response	NNS
cord-298458-p7rvupjo	73	35	to	to	IN
cord-298458-p7rvupjo	73	36	IAV	IAV	NNP
cord-298458-p7rvupjo	73	37	in	in	IN
cord-298458-p7rvupjo	73	38	humans	human	NNS
cord-298458-p7rvupjo	73	39	may	may	MD
cord-298458-p7rvupjo	73	40	be	be	VB
cord-298458-p7rvupjo	73	41	more	more	RBR
cord-298458-p7rvupjo	73	42	stable	stable	JJ
cord-298458-p7rvupjo	73	43	than	than	IN
cord-298458-p7rvupjo	73	44	RSV	RSV	NNP
cord-298458-p7rvupjo	73	45	(	(	-LRB-
cord-298458-p7rvupjo	73	46	57	57	CD
cord-298458-p7rvupjo	73	47	)	)	-RRB-
cord-298458-p7rvupjo	73	48	.	.	.
cord-298458-p7rvupjo	74	1	Memory	memory	NN
cord-298458-p7rvupjo	74	2	CD8	CD8	NNP
cord-298458-p7rvupjo	74	3	T	T	NNP
cord-298458-p7rvupjo	74	4	cells	cell	NNS
cord-298458-p7rvupjo	74	5	rapidly	rapidly	RB
cord-298458-p7rvupjo	74	6	expand	expand	VBP
cord-298458-p7rvupjo	74	7	in	in	IN
cord-298458-p7rvupjo	74	8	the	the	DT
cord-298458-p7rvupjo	74	9	lung	lung	NN
cord-298458-p7rvupjo	74	10	following	follow	VBG
cord-298458-p7rvupjo	74	11	a	a	DT
cord-298458-p7rvupjo	74	12	secondary	secondary	JJ
cord-298458-p7rvupjo	74	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	74	14	virus	virus	NN
cord-298458-p7rvupjo	74	15	infection	infection	NN
cord-298458-p7rvupjo	74	16	in	in	IN
cord-298458-p7rvupjo	74	17	both	both	DT
cord-298458-p7rvupjo	74	18	mice	mouse	NNS
cord-298458-p7rvupjo	74	19	and	and	CC
cord-298458-p7rvupjo	74	20	humans	human	NNS
cord-298458-p7rvupjo	74	21	(	(	-LRB-
cord-298458-p7rvupjo	74	22	35	35	CD
cord-298458-p7rvupjo	74	23	,	,	,
cord-298458-p7rvupjo	74	24	38	38	CD
cord-298458-p7rvupjo	74	25	,	,	,
cord-298458-p7rvupjo	74	26	39	39	CD
cord-298458-p7rvupjo	74	27	,	,	,
cord-298458-p7rvupjo	74	28	44	44	CD
cord-298458-p7rvupjo	74	29	,	,	,
cord-298458-p7rvupjo	74	30	49	49	CD
cord-298458-p7rvupjo	74	31	)	)	-RRB-
cord-298458-p7rvupjo	74	32	.	.	.
cord-298458-p7rvupjo	75	1	The	the	DT
cord-298458-p7rvupjo	75	2	observed	observed	JJ
cord-298458-p7rvupjo	75	3	expansion	expansion	NN
cord-298458-p7rvupjo	75	4	is	be	VBZ
cord-298458-p7rvupjo	75	5	primarily	primarily	RB
cord-298458-p7rvupjo	75	6	due	due	JJ
cord-298458-p7rvupjo	75	7	to	to	IN
cord-298458-p7rvupjo	75	8	the	the	DT
cord-298458-p7rvupjo	75	9	migration	migration	NN
cord-298458-p7rvupjo	75	10	of	of	IN
cord-298458-p7rvupjo	75	11	circulating	circulate	VBG
cord-298458-p7rvupjo	75	12	CD8	CD8	NNP
cord-298458-p7rvupjo	75	13	T	T	NNP
cord-298458-p7rvupjo	75	14	cells	cell	NNS
cord-298458-p7rvupjo	75	15	into	into	IN
cord-298458-p7rvupjo	75	16	the	the	DT
cord-298458-p7rvupjo	75	17	lung	lung	NN
cord-298458-p7rvupjo	75	18	and	and	CC
cord-298458-p7rvupjo	75	19	airways	airways	NNP
cord-298458-p7rvupjo	75	20	,	,	,
cord-298458-p7rvupjo	75	21	rather	rather	RB
cord-298458-p7rvupjo	75	22	than	than	IN
cord-298458-p7rvupjo	75	23	proliferation	proliferation	NN
cord-298458-p7rvupjo	75	24	of	of	IN
cord-298458-p7rvupjo	75	25	resident	resident	JJ
cord-298458-p7rvupjo	75	26	cells	cell	NNS
cord-298458-p7rvupjo	75	27	(	(	-LRB-
cord-298458-p7rvupjo	75	28	58	58	CD
cord-298458-p7rvupjo	75	29	)	)	-RRB-
cord-298458-p7rvupjo	75	30	.	.	.
cord-298458-p7rvupjo	76	1	The	the	DT
cord-298458-p7rvupjo	76	2	expansion	expansion	NN
cord-298458-p7rvupjo	76	3	of	of	IN
cord-298458-p7rvupjo	76	4	virus	virus	NN
cord-298458-p7rvupjo	76	5	-	-	HYPH
cord-298458-p7rvupjo	76	6	specific	specific	JJ
cord-298458-p7rvupjo	76	7	CD8	CD8	NNP
cord-298458-p7rvupjo	76	8	T	T	NNP
cord-298458-p7rvupjo	76	9	cells	cell	NNS
cord-298458-p7rvupjo	76	10	in	in	IN
cord-298458-p7rvupjo	76	11	the	the	DT
cord-298458-p7rvupjo	76	12	lung	lung	NN
cord-298458-p7rvupjo	76	13	and	and	CC
cord-298458-p7rvupjo	76	14	airways	airways	NNP
cord-298458-p7rvupjo	76	15	following	follow	VBG
cord-298458-p7rvupjo	76	16	infection	infection	NN
cord-298458-p7rvupjo	76	17	corresponds	correspond	VBZ
cord-298458-p7rvupjo	76	18	with	with	IN
cord-298458-p7rvupjo	76	19	an	an	DT
cord-298458-p7rvupjo	76	20	increase	increase	NN
cord-298458-p7rvupjo	76	21	in	in	IN
cord-298458-p7rvupjo	76	22	CXCR3-and	cxcr3-and	JJ
cord-298458-p7rvupjo	76	23	CCR5-binding	ccr5-binde	VBG
cord-298458-p7rvupjo	76	24	chemokines	chemokine	NNS
cord-298458-p7rvupjo	76	25	,	,	,
cord-298458-p7rvupjo	76	26	supporting	support	VBG
cord-298458-p7rvupjo	76	27	a	a	DT
cord-298458-p7rvupjo	76	28	role	role	NN
cord-298458-p7rvupjo	76	29	for	for	IN
cord-298458-p7rvupjo	76	30	chemokine	chemokine	NN
cord-298458-p7rvupjo	76	31	-	-	HYPH
cord-298458-p7rvupjo	76	32	mediated	mediate	VBN
cord-298458-p7rvupjo	76	33	migration	migration	NN
cord-298458-p7rvupjo	76	34	of	of	IN
cord-298458-p7rvupjo	76	35	CD8	CD8	NNP
cord-298458-p7rvupjo	76	36	T	T	NNP
cord-298458-p7rvupjo	76	37	cells	cell	NNS
cord-298458-p7rvupjo	76	38	following	follow	VBG
cord-298458-p7rvupjo	76	39	secondary	secondary	JJ
cord-298458-p7rvupjo	76	40	infection	infection	NN
cord-298458-p7rvupjo	76	41	(	(	-LRB-
cord-298458-p7rvupjo	76	42	59	59	CD
cord-298458-p7rvupjo	76	43	)	)	-RRB-
cord-298458-p7rvupjo	76	44	.	.	.
cord-298458-p7rvupjo	77	1	Indeed	indeed	RB
cord-298458-p7rvupjo	77	2	,	,	,
cord-298458-p7rvupjo	77	3	CCR5	ccr5	JJ
cord-298458-p7rvupjo	77	4	expression	expression	NN
cord-298458-p7rvupjo	77	5	on	on	IN
cord-298458-p7rvupjo	77	6	memory	memory	NN
cord-298458-p7rvupjo	77	7	CD8	CD8	NNP
cord-298458-p7rvupjo	77	8	T	T	NNP
cord-298458-p7rvupjo	77	9	cells	cell	NNS
cord-298458-p7rvupjo	77	10	is	be	VBZ
cord-298458-p7rvupjo	77	11	required	require	VBN
cord-298458-p7rvupjo	77	12	for	for	IN
cord-298458-p7rvupjo	77	13	their	-PRON-	PRP$
cord-298458-p7rvupjo	77	14	early	early	JJ
cord-298458-p7rvupjo	77	15	recruitment	recruitment	NN
cord-298458-p7rvupjo	77	16	into	into	IN
cord-298458-p7rvupjo	77	17	the	the	DT
cord-298458-p7rvupjo	77	18	airways	airway	NNS
cord-298458-p7rvupjo	77	19	after	after	IN
cord-298458-p7rvupjo	77	20	secondary	secondary	JJ
cord-298458-p7rvupjo	77	21	infection	infection	NN
cord-298458-p7rvupjo	77	22	,	,	,
cord-298458-p7rvupjo	77	23	but	but	CC
cord-298458-p7rvupjo	77	24	not	not	RB
cord-298458-p7rvupjo	77	25	to	to	IN
cord-298458-p7rvupjo	77	26	the	the	DT
cord-298458-p7rvupjo	77	27	lung	lung	NN
cord-298458-p7rvupjo	77	28	parenchyma	parenchyma	NN
cord-298458-p7rvupjo	77	29	(	(	-LRB-
cord-298458-p7rvupjo	77	30	59	59	CD
cord-298458-p7rvupjo	77	31	)	)	-RRB-
cord-298458-p7rvupjo	77	32	.	.	.
cord-298458-p7rvupjo	78	1	Following	follow	VBG
cord-298458-p7rvupjo	78	2	secondary	secondary	JJ
cord-298458-p7rvupjo	78	3	expansion	expansion	NN
cord-298458-p7rvupjo	78	4	,	,	,
cord-298458-p7rvupjo	78	5	memory	memory	NN
cord-298458-p7rvupjo	78	6	CD8	CD8	NNP
cord-298458-p7rvupjo	78	7	T	T	NNP
cord-298458-p7rvupjo	78	8	cells	cell	NNS
cord-298458-p7rvupjo	78	9	rapidly	rapidly	RB
cord-298458-p7rvupjo	78	10	produce	produce	VBP
cord-298458-p7rvupjo	78	11	effector	effector	NN
cord-298458-p7rvupjo	78	12	cytokines	cytokine	NNS
cord-298458-p7rvupjo	78	13	such	such	JJ
cord-298458-p7rvupjo	78	14	as	as	IN
cord-298458-p7rvupjo	78	15	IFN	IFN	NNP
cord-298458-p7rvupjo	78	16	-	-	HYPH
cord-298458-p7rvupjo	78	17	γ	γ	NNP
cord-298458-p7rvupjo	78	18	and	and	CC
cord-298458-p7rvupjo	78	19	TNF	TNF	NNP
cord-298458-p7rvupjo	78	20	(	(	-LRB-
cord-298458-p7rvupjo	78	21	30	30	CD
cord-298458-p7rvupjo	78	22	,	,	,
cord-298458-p7rvupjo	78	23	38	38	CD
cord-298458-p7rvupjo	78	24	,	,	,
cord-298458-p7rvupjo	78	25	60	60	CD
cord-298458-p7rvupjo	78	26	)	)	-RRB-
cord-298458-p7rvupjo	78	27	.	.	.
cord-298458-p7rvupjo	79	1	Additionally	additionally	RB
cord-298458-p7rvupjo	79	2	,	,	,
cord-298458-p7rvupjo	79	3	virus	virus	NN
cord-298458-p7rvupjo	79	4	-	-	HYPH
cord-298458-p7rvupjo	79	5	specific	specific	JJ
cord-298458-p7rvupjo	79	6	memory	memory	NN
cord-298458-p7rvupjo	79	7	CD8	CD8	NNP
cord-298458-p7rvupjo	79	8	T	T	NNP
cord-298458-p7rvupjo	79	9	cells	cell	NNS
cord-298458-p7rvupjo	79	10	express	express	VBP
cord-298458-p7rvupjo	79	11	high	high	JJ
cord-298458-p7rvupjo	79	12	levels	level	NNS
cord-298458-p7rvupjo	79	13	of	of	IN
cord-298458-p7rvupjo	79	14	CD11a	CD11a	NNS
cord-298458-p7rvupjo	79	15	and	and	CC
cord-298458-p7rvupjo	79	16	produce	produce	VB
cord-298458-p7rvupjo	79	17	cytolytic	cytolytic	JJ
cord-298458-p7rvupjo	79	18	molecules	molecule	NNS
cord-298458-p7rvupjo	79	19	,	,	,
cord-298458-p7rvupjo	79	20	such	such	JJ
cord-298458-p7rvupjo	79	21	as	as	IN
cord-298458-p7rvupjo	79	22	granzyme	granzyme	NNP
cord-298458-p7rvupjo	79	23	B	B	NNP
cord-298458-p7rvupjo	79	24	,	,	,
cord-298458-p7rvupjo	79	25	after	after	IN
cord-298458-p7rvupjo	79	26	infection	infection	NN
cord-298458-p7rvupjo	79	27	(	(	-LRB-
cord-298458-p7rvupjo	79	28	61	61	CD
cord-298458-p7rvupjo	79	29	,	,	,
cord-298458-p7rvupjo	79	30	62	62	CD
cord-298458-p7rvupjo	79	31	)	)	-RRB-
cord-298458-p7rvupjo	79	32	.	.	.
cord-298458-p7rvupjo	80	1	These	these	DT
cord-298458-p7rvupjo	80	2	effector	effector	NN
cord-298458-p7rvupjo	80	3	functions	function	NNS
cord-298458-p7rvupjo	80	4	of	of	IN
cord-298458-p7rvupjo	80	5	respiratory	respiratory	JJ
cord-298458-p7rvupjo	80	6	virus	virus	NN
cord-298458-p7rvupjo	80	7	-	-	HYPH
cord-298458-p7rvupjo	80	8	specific	specific	JJ
cord-298458-p7rvupjo	80	9	memory	memory	NN
cord-298458-p7rvupjo	80	10	CD8	CD8	NNP
cord-298458-p7rvupjo	80	11	T	T	NNP
cord-298458-p7rvupjo	80	12	cells	cell	NNS
cord-298458-p7rvupjo	80	13	are	be	VBP
cord-298458-p7rvupjo	80	14	critical	critical	JJ
cord-298458-p7rvupjo	80	15	for	for	IN
cord-298458-p7rvupjo	80	16	mediating	mediate	VBG
cord-298458-p7rvupjo	80	17	viral	viral	JJ
cord-298458-p7rvupjo	80	18	clearance	clearance	NN
cord-298458-p7rvupjo	80	19	and	and	CC
cord-298458-p7rvupjo	80	20	protecting	protect	VBG
cord-298458-p7rvupjo	80	21	against	against	IN
cord-298458-p7rvupjo	80	22	infection	infection	NN
cord-298458-p7rvupjo	80	23	,	,	,
cord-298458-p7rvupjo	80	24	as	as	IN
cord-298458-p7rvupjo	80	25	discussed	discuss	VBN
cord-298458-p7rvupjo	80	26	below	below	RB
cord-298458-p7rvupjo	80	27	.	.	.
cord-298458-p7rvupjo	81	1	Based	base	VBN
cord-298458-p7rvupjo	81	2	on	on	IN
cord-298458-p7rvupjo	81	3	the	the	DT
cord-298458-p7rvupjo	81	4	expression	expression	NN
cord-298458-p7rvupjo	81	5	of	of	IN
cord-298458-p7rvupjo	81	6	activation	activation	NN
cord-298458-p7rvupjo	81	7	marker	marker	NN
cord-298458-p7rvupjo	81	8	CD45RA	cd45ra	NN
cord-298458-p7rvupjo	81	9	and	and	CC
cord-298458-p7rvupjo	81	10	lymphoid	lymphoid	JJ
cord-298458-p7rvupjo	81	11	homing	homing	NN
cord-298458-p7rvupjo	81	12	receptor	receptor	NN
cord-298458-p7rvupjo	81	13	CCR7	CCR7	NNP
cord-298458-p7rvupjo	81	14	,	,	,
cord-298458-p7rvupjo	81	15	human	human	JJ
cord-298458-p7rvupjo	81	16	memory	memory	NN
cord-298458-p7rvupjo	81	17	CD8	CD8	NNP
cord-298458-p7rvupjo	81	18	T	T	NNP
cord-298458-p7rvupjo	81	19	cells	cell	NNS
cord-298458-p7rvupjo	81	20	have	have	VBP
cord-298458-p7rvupjo	81	21	been	be	VBN
cord-298458-p7rvupjo	81	22	broadly	broadly	RB
cord-298458-p7rvupjo	81	23	separated	separate	VBN
cord-298458-p7rvupjo	81	24	into	into	IN
cord-298458-p7rvupjo	81	25	four	four	CD
cord-298458-p7rvupjo	81	26	major	major	JJ
cord-298458-p7rvupjo	81	27	subsets	subset	NNS
cord-298458-p7rvupjo	81	28	:	:	:
cord-298458-p7rvupjo	82	1	(	(	-LRB-
cord-298458-p7rvupjo	82	2	1	1	LS
cord-298458-p7rvupjo	82	3	)	)	-RRB-
cord-298458-p7rvupjo	82	4	naive	naive	JJ
cord-298458-p7rvupjo	82	5	(	(	-LRB-
cord-298458-p7rvupjo	82	6	CD45RA	cd45ra	NN
cord-298458-p7rvupjo	82	7	+	+	CC
cord-298458-p7rvupjo	82	8	CCR7	CCR7	NNP
cord-298458-p7rvupjo	82	9	+	+	SYM
cord-298458-p7rvupjo	82	10	)	)	-RRB-
cord-298458-p7rvupjo	82	11	,	,	,
cord-298458-p7rvupjo	82	12	(	(	-LRB-
cord-298458-p7rvupjo	82	13	2	2	LS
cord-298458-p7rvupjo	82	14	)	)	-RRB-
cord-298458-p7rvupjo	82	15	central	central	JJ
cord-298458-p7rvupjo	82	16	memory	memory	NN
cord-298458-p7rvupjo	82	17	(	(	-LRB-
cord-298458-p7rvupjo	82	18	TCM	TCM	NNP
cord-298458-p7rvupjo	82	19	;	;	:
cord-298458-p7rvupjo	82	20	CD45RA	cd45ra	NN
cord-298458-p7rvupjo	82	21	-CCR7	-ccr7	NN
cord-298458-p7rvupjo	82	22	+	+	SYM
cord-298458-p7rvupjo	82	23	)	)	-RRB-
cord-298458-p7rvupjo	82	24	,	,	,
cord-298458-p7rvupjo	82	25	(	(	-LRB-
cord-298458-p7rvupjo	82	26	3	3	LS
cord-298458-p7rvupjo	82	27	)	)	-RRB-
cord-298458-p7rvupjo	82	28	effector	effector	VB
cord-298458-p7rvupjo	82	29	memory	memory	NN
cord-298458-p7rvupjo	82	30	(	(	-LRB-
cord-298458-p7rvupjo	82	31	TEM	tem	NN
cord-298458-p7rvupjo	82	32	;	;	:
cord-298458-p7rvupjo	82	33	CD45RA	CD45RA	NNP
cord-298458-p7rvupjo	82	34	−	−	NNP
cord-298458-p7rvupjo	82	35	CCR7	CCR7	NNP
cord-298458-p7rvupjo	82	36	−	−	NNP
cord-298458-p7rvupjo	82	37	)	)	-RRB-
cord-298458-p7rvupjo	82	38	,	,	,
cord-298458-p7rvupjo	82	39	and	and	CC
cord-298458-p7rvupjo	82	40	(	(	-LRB-
cord-298458-p7rvupjo	82	41	4	4	LS
cord-298458-p7rvupjo	82	42	)	)	-RRB-
cord-298458-p7rvupjo	82	43	late	late	JJ
cord-298458-p7rvupjo	82	44	effector	effector	NN
cord-298458-p7rvupjo	82	45	memory	memory	NN
cord-298458-p7rvupjo	82	46	(	(	-LRB-
cord-298458-p7rvupjo	82	47	TEMRA	temra	NN
cord-298458-p7rvupjo	82	48	;	;	:
cord-298458-p7rvupjo	82	49	CD45RA	cd45ra	NN
cord-298458-p7rvupjo	82	50	+	+	CC
cord-298458-p7rvupjo	82	51	CCR7	CCR7	NNP
cord-298458-p7rvupjo	82	52	−	−	NNP
cord-298458-p7rvupjo	82	53	)	)	-RRB-
cord-298458-p7rvupjo	82	54	(	(	-LRB-
cord-298458-p7rvupjo	82	55	63	63	CD
cord-298458-p7rvupjo	82	56	)	)	-RRB-
cord-298458-p7rvupjo	82	57	.	.	.
cord-298458-p7rvupjo	83	1	Due	due	IN
cord-298458-p7rvupjo	83	2	to	to	IN
cord-298458-p7rvupjo	83	3	their	-PRON-	PRP$
cord-298458-p7rvupjo	83	4	expression	expression	NN
cord-298458-p7rvupjo	83	5	of	of	IN
cord-298458-p7rvupjo	83	6	CCR7	CCR7	NNP
cord-298458-p7rvupjo	83	7	,	,	,
cord-298458-p7rvupjo	83	8	TCM	TCM	NNP
cord-298458-p7rvupjo	83	9	home	home	NN
cord-298458-p7rvupjo	83	10	primarily	primarily	RB
cord-298458-p7rvupjo	83	11	to	to	IN
cord-298458-p7rvupjo	83	12	secondary	secondary	JJ
cord-298458-p7rvupjo	83	13	lymphoid	lymphoid	JJ
cord-298458-p7rvupjo	83	14	organs	organ	NNS
cord-298458-p7rvupjo	83	15	,	,	,
cord-298458-p7rvupjo	83	16	while	while	IN
cord-298458-p7rvupjo	83	17	TEM	tem	NN
cord-298458-p7rvupjo	83	18	migrate	migrate	VBP
cord-298458-p7rvupjo	83	19	to	to	IN
cord-298458-p7rvupjo	83	20	peripheral	peripheral	JJ
cord-298458-p7rvupjo	83	21	tissues	tissue	NNS
cord-298458-p7rvupjo	83	22	and	and	CC
cord-298458-p7rvupjo	83	23	rapidly	rapidly	RB
cord-298458-p7rvupjo	83	24	exert	exert	VB
cord-298458-p7rvupjo	83	25	effector	effector	NN
cord-298458-p7rvupjo	83	26	functions	function	NNS
cord-298458-p7rvupjo	83	27	.	.	.
cord-298458-p7rvupjo	84	1	TEMRA	TEMRA	NNP
cord-298458-p7rvupjo	84	2	are	be	VBP
cord-298458-p7rvupjo	84	3	a	a	DT
cord-298458-p7rvupjo	84	4	subset	subset	NN
cord-298458-p7rvupjo	84	5	of	of	IN
cord-298458-p7rvupjo	84	6	TEM	tem	NN
cord-298458-p7rvupjo	84	7	cells	cell	NNS
cord-298458-p7rvupjo	84	8	that	that	WDT
cord-298458-p7rvupjo	84	9	have	have	VBP
cord-298458-p7rvupjo	84	10	re	re	VBN
cord-298458-p7rvupjo	84	11	-	-	VBN
cord-298458-p7rvupjo	84	12	expressed	express	VBN
cord-298458-p7rvupjo	84	13	CD45RA	cd45ra	NN
cord-298458-p7rvupjo	84	14	.	.	.
cord-298458-p7rvupjo	85	1	They	-PRON-	PRP
cord-298458-p7rvupjo	85	2	exhibit	exhibit	VBP
cord-298458-p7rvupjo	85	3	reduced	reduce	VBN
cord-298458-p7rvupjo	85	4	proliferative	proliferative	JJ
cord-298458-p7rvupjo	85	5	and	and	CC
cord-298458-p7rvupjo	85	6	functional	functional	JJ
cord-298458-p7rvupjo	85	7	capacity	capacity	NN
cord-298458-p7rvupjo	85	8	,	,	,
cord-298458-p7rvupjo	85	9	and	and	CC
cord-298458-p7rvupjo	85	10	thus	thus	RB
cord-298458-p7rvupjo	85	11	are	be	VBP
cord-298458-p7rvupjo	85	12	considered	consider	VBN
cord-298458-p7rvupjo	85	13	to	to	TO
cord-298458-p7rvupjo	85	14	be	be	VB
cord-298458-p7rvupjo	85	15	terminally	terminally	RB
cord-298458-p7rvupjo	85	16	differentiated	differentiate	VBN
cord-298458-p7rvupjo	85	17	cells	cell	NNS
cord-298458-p7rvupjo	85	18	.	.	.
cord-298458-p7rvupjo	86	1	Human	human	JJ
cord-298458-p7rvupjo	86	2	virus	virus	NN
cord-298458-p7rvupjo	86	3	-	-	HYPH
cord-298458-p7rvupjo	86	4	specific	specific	JJ
cord-298458-p7rvupjo	86	5	memory	memory	NN
cord-298458-p7rvupjo	86	6	CD8	CD8	NNP
cord-298458-p7rvupjo	86	7	T	T	NNP
cord-298458-p7rvupjo	86	8	cell	cell	NN
cord-298458-p7rvupjo	86	9	populations	population	NNS
cord-298458-p7rvupjo	86	10	are	be	VBP
cord-298458-p7rvupjo	86	11	typically	typically	RB
cord-298458-p7rvupjo	86	12	composed	compose	VBN
cord-298458-p7rvupjo	86	13	of	of	IN
cord-298458-p7rvupjo	86	14	a	a	DT
cord-298458-p7rvupjo	86	15	combination	combination	NN
cord-298458-p7rvupjo	86	16	of	of	IN
cord-298458-p7rvupjo	86	17	TEM	tem	NN
cord-298458-p7rvupjo	86	18	and	and	CC
cord-298458-p7rvupjo	86	19	TEMRA	TEMRA	NNP
cord-298458-p7rvupjo	86	20	within	within	IN
cord-298458-p7rvupjo	86	21	the	the	DT
cord-298458-p7rvupjo	86	22	peripheral	peripheral	JJ
cord-298458-p7rvupjo	86	23	blood	blood	NN
cord-298458-p7rvupjo	86	24	(	(	-LRB-
cord-298458-p7rvupjo	86	25	44	44	CD
cord-298458-p7rvupjo	86	26	,	,	,
cord-298458-p7rvupjo	86	27	46	46	CD
cord-298458-p7rvupjo	86	28	,	,	,
cord-298458-p7rvupjo	86	29	50	50	CD
cord-298458-p7rvupjo	86	30	,	,	,
cord-298458-p7rvupjo	86	31	52	52	CD
cord-298458-p7rvupjo	86	32	,	,	,
cord-298458-p7rvupjo	86	33	55	55	CD
cord-298458-p7rvupjo	86	34	)	)	-RRB-
cord-298458-p7rvupjo	86	35	.	.	.
cord-298458-p7rvupjo	87	1	Alternatively	alternatively	RB
cord-298458-p7rvupjo	87	2	,	,	,
cord-298458-p7rvupjo	87	3	RSV	RSV	NNP
cord-298458-p7rvupjo	87	4	-	-	HYPH
cord-298458-p7rvupjo	87	5	specific	specific	JJ
cord-298458-p7rvupjo	87	6	memory	memory	NN
cord-298458-p7rvupjo	87	7	CD8	CD8	NNP
cord-298458-p7rvupjo	87	8	T	T	NNP
cord-298458-p7rvupjo	87	9	cells	cell	NNS
cord-298458-p7rvupjo	87	10	located	locate	VBN
cord-298458-p7rvupjo	87	11	in	in	IN
cord-298458-p7rvupjo	87	12	the	the	DT
cord-298458-p7rvupjo	87	13	airways	airway	NNS
cord-298458-p7rvupjo	87	14	in	in	IN
cord-298458-p7rvupjo	87	15	both	both	DT
cord-298458-p7rvupjo	87	16	adults	adult	NNS
cord-298458-p7rvupjo	87	17	and	and	CC
cord-298458-p7rvupjo	87	18	infants	infant	NNS
cord-298458-p7rvupjo	87	19	are	be	VBP
cord-298458-p7rvupjo	87	20	primarily	primarily	RB
cord-298458-p7rvupjo	87	21	of	of	IN
cord-298458-p7rvupjo	87	22	TEM	tem	NN
cord-298458-p7rvupjo	87	23	phenotype	phenotype	NN
cord-298458-p7rvupjo	87	24	and	and	CC
cord-298458-p7rvupjo	87	25	also	also	RB
cord-298458-p7rvupjo	87	26	express	express	VB
cord-298458-p7rvupjo	87	27	high	high	JJ
cord-298458-p7rvupjo	87	28	levels	level	NNS
cord-298458-p7rvupjo	87	29	of	of	IN
cord-298458-p7rvupjo	87	30	CD27	CD27	NNP
cord-298458-p7rvupjo	87	31	,	,	,
cord-298458-p7rvupjo	87	32	CD28	CD28	NNP
cord-298458-p7rvupjo	87	33	,	,	,
cord-298458-p7rvupjo	87	34	and	and	CC
cord-298458-p7rvupjo	87	35	CCR5	CCR5	NNP
cord-298458-p7rvupjo	87	36	and	and	CC
cord-298458-p7rvupjo	87	37	low	low	JJ
cord-298458-p7rvupjo	87	38	levels	level	NNS
cord-298458-p7rvupjo	87	39	of	of	IN
cord-298458-p7rvupjo	87	40	CD62L	cd62l	NN
cord-298458-p7rvupjo	87	41	(	(	-LRB-
cord-298458-p7rvupjo	87	42	46	46	CD
cord-298458-p7rvupjo	87	43	,	,	,
cord-298458-p7rvupjo	87	44	49	49	CD
cord-298458-p7rvupjo	87	45	)	)	-RRB-
cord-298458-p7rvupjo	87	46	.	.	.
cord-298458-p7rvupjo	88	1	Together	together	RB
cord-298458-p7rvupjo	88	2	,	,	,
cord-298458-p7rvupjo	88	3	these	these	DT
cord-298458-p7rvupjo	88	4	studies	study	NNS
cord-298458-p7rvupjo	88	5	indicate	indicate	VBP
cord-298458-p7rvupjo	88	6	that	that	IN
cord-298458-p7rvupjo	88	7	TEM	TEM	NNP
cord-298458-p7rvupjo	88	8	CD8	CD8	NNP
cord-298458-p7rvupjo	88	9	T	T	NNP
cord-298458-p7rvupjo	88	10	cells	cell	NNS
cord-298458-p7rvupjo	88	11	are	be	VBP
cord-298458-p7rvupjo	88	12	dominant	dominant	JJ
cord-298458-p7rvupjo	88	13	following	follow	VBG
cord-298458-p7rvupjo	88	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	88	15	virus	virus	NN
cord-298458-p7rvupjo	88	16	infection	infection	NN
cord-298458-p7rvupjo	88	17	in	in	IN
cord-298458-p7rvupjo	88	18	humans	human	NNS
cord-298458-p7rvupjo	88	19	.	.	.
cord-298458-p7rvupjo	89	1	Given	give	VBN
cord-298458-p7rvupjo	89	2	the	the	DT
cord-298458-p7rvupjo	89	3	frequent	frequent	JJ
cord-298458-p7rvupjo	89	4	exposure	exposure	NN
cord-298458-p7rvupjo	89	5	to	to	IN
cord-298458-p7rvupjo	89	6	viruses	virus	NNS
cord-298458-p7rvupjo	89	7	in	in	IN
cord-298458-p7rvupjo	89	8	the	the	DT
cord-298458-p7rvupjo	89	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	89	10	tract	tract	NN
cord-298458-p7rvupjo	89	11	,	,	,
cord-298458-p7rvupjo	89	12	TEM	tem	NN
cord-298458-p7rvupjo	89	13	cells	cell	NNS
cord-298458-p7rvupjo	89	14	may	may	MD
cord-298458-p7rvupjo	89	15	be	be	VB
cord-298458-p7rvupjo	89	16	critical	critical	JJ
cord-298458-p7rvupjo	89	17	for	for	IN
cord-298458-p7rvupjo	89	18	the	the	DT
cord-298458-p7rvupjo	89	19	rapid	rapid	JJ
cord-298458-p7rvupjo	89	20	employment	employment	NN
cord-298458-p7rvupjo	89	21	of	of	IN
cord-298458-p7rvupjo	89	22	CD8	CD8	NNP
cord-298458-p7rvupjo	89	23	T	T	NNP
cord-298458-p7rvupjo	89	24	cell	cell	NN
cord-298458-p7rvupjo	89	25	effector	effector	NN
cord-298458-p7rvupjo	89	26	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	89	27	following	follow	VBG
cord-298458-p7rvupjo	89	28	reinfection	reinfection	NN
cord-298458-p7rvupjo	89	29	.	.	.
cord-298458-p7rvupjo	90	1	Recently	recently	RB
cord-298458-p7rvupjo	90	2	,	,	,
cord-298458-p7rvupjo	90	3	an	an	DT
cord-298458-p7rvupjo	90	4	additional	additional	JJ
cord-298458-p7rvupjo	90	5	population	population	NN
cord-298458-p7rvupjo	90	6	of	of	IN
cord-298458-p7rvupjo	90	7	memory	memory	NN
cord-298458-p7rvupjo	90	8	CD8	CD8	NNP
cord-298458-p7rvupjo	90	9	T	T	NNP
cord-298458-p7rvupjo	90	10	cells	cell	NNS
cord-298458-p7rvupjo	90	11	that	that	WDT
cord-298458-p7rvupjo	90	12	persist	persist	VBP
cord-298458-p7rvupjo	90	13	within	within	IN
cord-298458-p7rvupjo	90	14	peripheral	peripheral	JJ
cord-298458-p7rvupjo	90	15	tissues	tissue	NNS
cord-298458-p7rvupjo	90	16	has	have	VBZ
cord-298458-p7rvupjo	90	17	been	be	VBN
cord-298458-p7rvupjo	90	18	identified	identify	VBN
cord-298458-p7rvupjo	90	19	,	,	,
cord-298458-p7rvupjo	90	20	termed	term	VBN
cord-298458-p7rvupjo	90	21	tissue	tissue	NN
cord-298458-p7rvupjo	90	22	-	-	HYPH
cord-298458-p7rvupjo	90	23	resident	resident	NN
cord-298458-p7rvupjo	90	24	memory	memory	NN
cord-298458-p7rvupjo	90	25	CD8	CD8	NNP
cord-298458-p7rvupjo	90	26	T	T	NNP
cord-298458-p7rvupjo	90	27	cells	cell	NNS
cord-298458-p7rvupjo	90	28	(	(	-LRB-
cord-298458-p7rvupjo	90	29	TRM	TRM	NNP
cord-298458-p7rvupjo	90	30	)	)	-RRB-
cord-298458-p7rvupjo	90	31	(	(	-LRB-
cord-298458-p7rvupjo	90	32	64	64	CD
cord-298458-p7rvupjo	90	33	)	)	-RRB-
cord-298458-p7rvupjo	90	34	.	.	.
cord-298458-p7rvupjo	91	1	TRM	TRM	NNP
cord-298458-p7rvupjo	91	2	have	have	VBP
cord-298458-p7rvupjo	91	3	been	be	VBN
cord-298458-p7rvupjo	91	4	observed	observe	VBN
cord-298458-p7rvupjo	91	5	within	within	IN
cord-298458-p7rvupjo	91	6	several	several	JJ
cord-298458-p7rvupjo	91	7	peripheral	peripheral	JJ
cord-298458-p7rvupjo	91	8	organs	organ	NNS
cord-298458-p7rvupjo	91	9	including	include	VBG
cord-298458-p7rvupjo	91	10	the	the	DT
cord-298458-p7rvupjo	91	11	intestine	intestine	NN
cord-298458-p7rvupjo	91	12	,	,	,
cord-298458-p7rvupjo	91	13	skin	skin	NN
cord-298458-p7rvupjo	91	14	,	,	,
cord-298458-p7rvupjo	91	15	female	female	JJ
cord-298458-p7rvupjo	91	16	reproductive	reproductive	JJ
cord-298458-p7rvupjo	91	17	tract	tract	NN
cord-298458-p7rvupjo	91	18	,	,	,
cord-298458-p7rvupjo	91	19	and	and	CC
cord-298458-p7rvupjo	91	20	lung	lung	NN
cord-298458-p7rvupjo	91	21	.	.	.
cord-298458-p7rvupjo	92	1	TRM	TRM	NNP
cord-298458-p7rvupjo	92	2	generated	generate	VBD
cord-298458-p7rvupjo	92	3	following	follow	VBG
cord-298458-p7rvupjo	92	4	a	a	DT
cord-298458-p7rvupjo	92	5	respiratory	respiratory	JJ
cord-298458-p7rvupjo	92	6	virus	virus	NN
cord-298458-p7rvupjo	92	7	infection	infection	NN
cord-298458-p7rvupjo	92	8	represent	represent	VBP
cord-298458-p7rvupjo	92	9	a	a	DT
cord-298458-p7rvupjo	92	10	non	non	JJ
cord-298458-p7rvupjo	92	11	-	-	JJ
cord-298458-p7rvupjo	92	12	circulating	circulating	JJ
cord-298458-p7rvupjo	92	13	population	population	NN
cord-298458-p7rvupjo	92	14	of	of	IN
cord-298458-p7rvupjo	92	15	memory	memory	NN
cord-298458-p7rvupjo	92	16	CD8	CD8	NNP
cord-298458-p7rvupjo	92	17	T	T	NNP
cord-298458-p7rvupjo	92	18	cells	cell	NNS
cord-298458-p7rvupjo	92	19	that	that	WDT
cord-298458-p7rvupjo	92	20	are	be	VBP
cord-298458-p7rvupjo	92	21	maintained	maintain	VBN
cord-298458-p7rvupjo	92	22	within	within	IN
cord-298458-p7rvupjo	92	23	the	the	DT
cord-298458-p7rvupjo	92	24	lung	lung	NN
cord-298458-p7rvupjo	92	25	parenchyma	parenchyma	NN
cord-298458-p7rvupjo	92	26	(	(	-LRB-
cord-298458-p7rvupjo	92	27	65	65	CD
cord-298458-p7rvupjo	92	28	)	)	-RRB-
cord-298458-p7rvupjo	92	29	.	.	.
cord-298458-p7rvupjo	93	1	Virus	virus	NN
cord-298458-p7rvupjo	93	2	-	-	HYPH
cord-298458-p7rvupjo	93	3	specific	specific	JJ
cord-298458-p7rvupjo	93	4	TRM	TRM	NNP
cord-298458-p7rvupjo	93	5	are	be	VBP
cord-298458-p7rvupjo	93	6	located	locate	VBN
cord-298458-p7rvupjo	93	7	along	along	IN
cord-298458-p7rvupjo	93	8	the	the	DT
cord-298458-p7rvupjo	93	9	wall	wall	NN
cord-298458-p7rvupjo	93	10	of	of	IN
cord-298458-p7rvupjo	93	11	large	large	JJ
cord-298458-p7rvupjo	93	12	airways	airway	NNS
cord-298458-p7rvupjo	93	13	and	and	CC
cord-298458-p7rvupjo	93	14	within	within	IN
cord-298458-p7rvupjo	93	15	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	93	16	tissue	tissue	NN
cord-298458-p7rvupjo	93	17	surrounding	surround	VBG
cord-298458-p7rvupjo	93	18	bronchioles	bronchiole	NNS
cord-298458-p7rvupjo	93	19	and	and	CC
cord-298458-p7rvupjo	93	20	alveoli	alveolus	NNS
cord-298458-p7rvupjo	93	21	(	(	-LRB-
cord-298458-p7rvupjo	93	22	66	66	CD
cord-298458-p7rvupjo	93	23	,	,	,
cord-298458-p7rvupjo	93	24	67	67	CD
cord-298458-p7rvupjo	93	25	)	)	-RRB-
cord-298458-p7rvupjo	93	26	.	.	.
cord-298458-p7rvupjo	94	1	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	94	2	virus	virus	NN
cord-298458-p7rvupjo	94	3	infection	infection	NN
cord-298458-p7rvupjo	94	4	also	also	RB
cord-298458-p7rvupjo	94	5	induces	induce	VBZ
cord-298458-p7rvupjo	94	6	TRM	TRM	NNP
cord-298458-p7rvupjo	94	7	within	within	IN
cord-298458-p7rvupjo	94	8	the	the	DT
cord-298458-p7rvupjo	94	9	airway	airway	NN
cord-298458-p7rvupjo	94	10	lumen	lumen	NNP
cord-298458-p7rvupjo	94	11	(	(	-LRB-
cord-298458-p7rvupjo	94	12	68	68	CD
cord-298458-p7rvupjo	94	13	,	,	,
cord-298458-p7rvupjo	94	14	69	69	CD
cord-298458-p7rvupjo	94	15	)	)	-RRB-
cord-298458-p7rvupjo	94	16	.	.	.
cord-298458-p7rvupjo	95	1	Airway	Airway	NNP
cord-298458-p7rvupjo	95	2	TRM	TRM	NNP
cord-298458-p7rvupjo	95	3	downregulate	downregulate	VBP
cord-298458-p7rvupjo	95	4	CD11a	CD11a	VBN
cord-298458-p7rvupjo	95	5	expression	expression	NN
cord-298458-p7rvupjo	95	6	and	and	CC
cord-298458-p7rvupjo	95	7	can	can	MD
cord-298458-p7rvupjo	95	8	be	be	VB
cord-298458-p7rvupjo	95	9	distinguished	distinguish	VBN
cord-298458-p7rvupjo	95	10	from	from	IN
cord-298458-p7rvupjo	95	11	recently	recently	RB
cord-298458-p7rvupjo	95	12	trafficked	traffic	VBN
cord-298458-p7rvupjo	95	13	CD8	CD8	NNP
cord-298458-p7rvupjo	95	14	T	T	NNP
cord-298458-p7rvupjo	95	15	cells	cell	NNS
cord-298458-p7rvupjo	95	16	that	that	WDT
cord-298458-p7rvupjo	95	17	express	express	VBP
cord-298458-p7rvupjo	95	18	high	high	JJ
cord-298458-p7rvupjo	95	19	levels	level	NNS
cord-298458-p7rvupjo	95	20	of	of	IN
cord-298458-p7rvupjo	95	21	CD11a	CD11a	NNS
cord-298458-p7rvupjo	95	22	(	(	-LRB-
cord-298458-p7rvupjo	95	23	70	70	CD
cord-298458-p7rvupjo	95	24	,	,	,
cord-298458-p7rvupjo	95	25	71	71	CD
cord-298458-p7rvupjo	95	26	)	)	-RRB-
cord-298458-p7rvupjo	95	27	.	.	.
cord-298458-p7rvupjo	96	1	The	the	DT
cord-298458-p7rvupjo	96	2	localization	localization	NN
cord-298458-p7rvupjo	96	3	of	of	IN
cord-298458-p7rvupjo	96	4	lung	lung	NN
cord-298458-p7rvupjo	96	5	and	and	CC
cord-298458-p7rvupjo	96	6	airway	airway	NN
cord-298458-p7rvupjo	96	7	TRM	TRM	NNP
cord-298458-p7rvupjo	96	8	following	follow	VBG
cord-298458-p7rvupjo	96	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	96	10	virus	virus	NN
cord-298458-p7rvupjo	96	11	infection	infection	NN
cord-298458-p7rvupjo	96	12	is	be	VBZ
cord-298458-p7rvupjo	96	13	distinctly	distinctly	RB
cord-298458-p7rvupjo	96	14	different	different	JJ
cord-298458-p7rvupjo	96	15	from	from	IN
cord-298458-p7rvupjo	96	16	that	that	DT
cord-298458-p7rvupjo	96	17	of	of	IN
cord-298458-p7rvupjo	96	18	TCM	TCM	NNP
cord-298458-p7rvupjo	96	19	,	,	,
cord-298458-p7rvupjo	96	20	which	which	WDT
cord-298458-p7rvupjo	96	21	traffic	traffic	NN
cord-298458-p7rvupjo	96	22	through	through	IN
cord-298458-p7rvupjo	96	23	the	the	DT
cord-298458-p7rvupjo	96	24	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	96	25	vasculature	vasculature	NN
cord-298458-p7rvupjo	96	26	and	and	CC
cord-298458-p7rvupjo	96	27	accumulate	accumulate	VBP
cord-298458-p7rvupjo	96	28	in	in	IN
cord-298458-p7rvupjo	96	29	the	the	DT
cord-298458-p7rvupjo	96	30	lung	lung	NN
cord-298458-p7rvupjo	96	31	-	-	HYPH
cord-298458-p7rvupjo	96	32	draining	drain	VBG
cord-298458-p7rvupjo	96	33	lymph	lymph	NN
cord-298458-p7rvupjo	96	34	node	node	NN
cord-298458-p7rvupjo	96	35	(	(	-LRB-
cord-298458-p7rvupjo	96	36	72	72	CD
cord-298458-p7rvupjo	96	37	,	,	,
cord-298458-p7rvupjo	96	38	73	73	CD
cord-298458-p7rvupjo	96	39	)	)	-RRB-
cord-298458-p7rvupjo	96	40	.	.	.
cord-298458-p7rvupjo	97	1	Virus	virus	NN
cord-298458-p7rvupjo	97	2	-	-	HYPH
cord-298458-p7rvupjo	97	3	specific	specific	JJ
cord-298458-p7rvupjo	97	4	TEM	tem	NN
cord-298458-p7rvupjo	97	5	are	be	VBP
cord-298458-p7rvupjo	97	6	also	also	RB
cord-298458-p7rvupjo	97	7	differentially	differentially	RB
cord-298458-p7rvupjo	97	8	located	locate	VBN
cord-298458-p7rvupjo	97	9	from	from	IN
cord-298458-p7rvupjo	97	10	TRM	TRM	NNP
cord-298458-p7rvupjo	97	11	residing	reside	VBG
cord-298458-p7rvupjo	97	12	primarily	primarily	RB
cord-298458-p7rvupjo	97	13	in	in	IN
cord-298458-p7rvupjo	97	14	the	the	DT
cord-298458-p7rvupjo	97	15	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	97	16	vasculature	vasculature	NN
cord-298458-p7rvupjo	97	17	or	or	CC
cord-298458-p7rvupjo	97	18	within	within	IN
cord-298458-p7rvupjo	97	19	the	the	DT
cord-298458-p7rvupjo	97	20	lung	lung	NN
cord-298458-p7rvupjo	97	21	tissue	tissue	NN
cord-298458-p7rvupjo	97	22	near	near	IN
cord-298458-p7rvupjo	97	23	blood	blood	NN
cord-298458-p7rvupjo	97	24	vessels	vessel	NNS
cord-298458-p7rvupjo	97	25	,	,	,
cord-298458-p7rvupjo	97	26	spacially	spacially	RB
cord-298458-p7rvupjo	97	27	distinct	distinct	JJ
cord-298458-p7rvupjo	97	28	from	from	IN
cord-298458-p7rvupjo	97	29	regions	region	NNS
cord-298458-p7rvupjo	97	30	that	that	WDT
cord-298458-p7rvupjo	97	31	contain	contain	VBP
cord-298458-p7rvupjo	97	32	TRM	TRM	NNP
cord-298458-p7rvupjo	97	33	(	(	-LRB-
cord-298458-p7rvupjo	97	34	67	67	CD
cord-298458-p7rvupjo	97	35	,	,	,
cord-298458-p7rvupjo	97	36	73	73	CD
cord-298458-p7rvupjo	97	37	)	)	-RRB-
cord-298458-p7rvupjo	97	38	.	.	.
cord-298458-p7rvupjo	98	1	Following	follow	VBG
cord-298458-p7rvupjo	98	2	either	either	CC
cord-298458-p7rvupjo	98	3	RSV	RSV	NNP
cord-298458-p7rvupjo	98	4	or	or	CC
cord-298458-p7rvupjo	98	5	IAV	IAV	NNP
cord-298458-p7rvupjo	98	6	infection	infection	NN
cord-298458-p7rvupjo	98	7	in	in	IN
cord-298458-p7rvupjo	98	8	mice	mice	NN
cord-298458-p7rvupjo	98	9	,	,	,
cord-298458-p7rvupjo	98	10	lung	lung	NN
cord-298458-p7rvupjo	98	11	and	and	CC
cord-298458-p7rvupjo	98	12	airway	airway	NN
cord-298458-p7rvupjo	98	13	TRM	TRM	NNP
cord-298458-p7rvupjo	98	14	are	be	VBP
cord-298458-p7rvupjo	98	15	induced	induce	VBN
cord-298458-p7rvupjo	98	16	and	and	CC
cord-298458-p7rvupjo	98	17	can	can	MD
cord-298458-p7rvupjo	98	18	be	be	VB
cord-298458-p7rvupjo	98	19	identified	identify	VBN
cord-298458-p7rvupjo	98	20	by	by	IN
cord-298458-p7rvupjo	98	21	their	-PRON-	PRP$
cord-298458-p7rvupjo	98	22	expression	expression	NN
cord-298458-p7rvupjo	98	23	of	of	IN
cord-298458-p7rvupjo	98	24	the	the	DT
cord-298458-p7rvupjo	98	25	canonical	canonical	JJ
cord-298458-p7rvupjo	98	26	resident	resident	JJ
cord-298458-p7rvupjo	98	27	memory	memory	NN
cord-298458-p7rvupjo	98	28	markers	marker	NNS
cord-298458-p7rvupjo	98	29	CD69	CD69	NNP
cord-298458-p7rvupjo	98	30	and	and	CC
cord-298458-p7rvupjo	98	31	CD103	CD103	NNP
cord-298458-p7rvupjo	98	32	,	,	,
cord-298458-p7rvupjo	98	33	which	which	WDT
cord-298458-p7rvupjo	98	34	promote	promote	VBP
cord-298458-p7rvupjo	98	35	their	-PRON-	PRP$
cord-298458-p7rvupjo	98	36	migration	migration	NN
cord-298458-p7rvupjo	98	37	to	to	IN
cord-298458-p7rvupjo	98	38	and	and	CC
cord-298458-p7rvupjo	98	39	retention	retention	NN
cord-298458-p7rvupjo	98	40	within	within	IN
cord-298458-p7rvupjo	98	41	the	the	DT
cord-298458-p7rvupjo	98	42	lung	lung	NN
cord-298458-p7rvupjo	98	43	tissue	tissue	NN
cord-298458-p7rvupjo	98	44	(	(	-LRB-
cord-298458-p7rvupjo	98	45	37	37	CD
cord-298458-p7rvupjo	98	46	,	,	,
cord-298458-p7rvupjo	98	47	65	65	CD
cord-298458-p7rvupjo	98	48	,	,	,
cord-298458-p7rvupjo	98	49	(	(	-LRB-
cord-298458-p7rvupjo	98	50	74	74	CD
cord-298458-p7rvupjo	98	51	)	)	-RRB-
cord-298458-p7rvupjo	99	1	(	(	-LRB-
cord-298458-p7rvupjo	99	2	75	75	CD
cord-298458-p7rvupjo	99	3	)	)	-RRB-
cord-298458-p7rvupjo	99	4	(	(	-LRB-
cord-298458-p7rvupjo	99	5	76	76	CD
cord-298458-p7rvupjo	99	6	)	)	-RRB-
cord-298458-p7rvupjo	99	7	.	.	.
cord-298458-p7rvupjo	100	1	IAV	IAV	NNP
cord-298458-p7rvupjo	100	2	-	-	:
cord-298458-p7rvupjo	100	3	and	and	CC
cord-298458-p7rvupjo	100	4	RSV	RSV	NNP
cord-298458-p7rvupjo	100	5	-	-	HYPH
cord-298458-p7rvupjo	100	6	specific	specific	JJ
cord-298458-p7rvupjo	100	7	TRM	TRM	NNP
cord-298458-p7rvupjo	100	8	are	be	VBP
cord-298458-p7rvupjo	100	9	also	also	RB
cord-298458-p7rvupjo	100	10	generated	generate	VBN
cord-298458-p7rvupjo	100	11	in	in	IN
cord-298458-p7rvupjo	100	12	the	the	DT
cord-298458-p7rvupjo	100	13	lungs	lung	NNS
cord-298458-p7rvupjo	100	14	of	of	IN
cord-298458-p7rvupjo	100	15	mice	mouse	NNS
cord-298458-p7rvupjo	100	16	that	that	WDT
cord-298458-p7rvupjo	100	17	have	have	VBP
cord-298458-p7rvupjo	100	18	been	be	VBN
cord-298458-p7rvupjo	100	19	locally	locally	RB
cord-298458-p7rvupjo	100	20	vaccinated	vaccinate	VBN
cord-298458-p7rvupjo	100	21	via	via	IN
cord-298458-p7rvupjo	100	22	an	an	DT
cord-298458-p7rvupjo	100	23	intranasal	intranasal	NN
cord-298458-p7rvupjo	100	24	route	route	NN
cord-298458-p7rvupjo	100	25	,	,	,
cord-298458-p7rvupjo	100	26	but	but	CC
cord-298458-p7rvupjo	100	27	not	not	RB
cord-298458-p7rvupjo	100	28	mice	mouse	NNS
cord-298458-p7rvupjo	100	29	that	that	WDT
cord-298458-p7rvupjo	100	30	have	have	VBP
cord-298458-p7rvupjo	100	31	been	be	VBN
cord-298458-p7rvupjo	100	32	immunized	immunize	VBN
cord-298458-p7rvupjo	100	33	systemically	systemically	RB
cord-298458-p7rvupjo	100	34	(	(	-LRB-
cord-298458-p7rvupjo	100	35	30	30	CD
cord-298458-p7rvupjo	100	36	,	,	,
cord-298458-p7rvupjo	100	37	(	(	-LRB-
cord-298458-p7rvupjo	100	38	77	77	CD
cord-298458-p7rvupjo	100	39	)	)	-RRB-
cord-298458-p7rvupjo	100	40	(	(	-LRB-
cord-298458-p7rvupjo	100	41	78	78	CD
cord-298458-p7rvupjo	100	42	)	)	-RRB-
cord-298458-p7rvupjo	100	43	(	(	-LRB-
cord-298458-p7rvupjo	100	44	79	79	CD
cord-298458-p7rvupjo	100	45	)	)	-RRB-
cord-298458-p7rvupjo	100	46	.	.	.
cord-298458-p7rvupjo	101	1	Importantly	importantly	RB
cord-298458-p7rvupjo	101	2	,	,	,
cord-298458-p7rvupjo	101	3	IAV	iav	NN
cord-298458-p7rvupjo	101	4	-	-	HYPH
cord-298458-p7rvupjo	101	5	specific	specific	JJ
cord-298458-p7rvupjo	101	6	TRM	TRM	NNP
cord-298458-p7rvupjo	101	7	expressing	express	VBG
cord-298458-p7rvupjo	101	8	CD69	CD69	NNP
cord-298458-p7rvupjo	101	9	were	be	VBD
cord-298458-p7rvupjo	101	10	also	also	RB
cord-298458-p7rvupjo	101	11	detected	detect	VBN
cord-298458-p7rvupjo	101	12	in	in	IN
cord-298458-p7rvupjo	101	13	human	human	JJ
cord-298458-p7rvupjo	101	14	lung	lung	NN
cord-298458-p7rvupjo	101	15	tissue	tissue	NN
cord-298458-p7rvupjo	101	16	sections	section	NNS
cord-298458-p7rvupjo	101	17	but	but	CC
cord-298458-p7rvupjo	101	18	were	be	VBD
cord-298458-p7rvupjo	101	19	absent	absent	JJ
cord-298458-p7rvupjo	101	20	from	from	IN
cord-298458-p7rvupjo	101	21	the	the	DT
cord-298458-p7rvupjo	101	22	spleen	spleen	NN
cord-298458-p7rvupjo	101	23	(	(	-LRB-
cord-298458-p7rvupjo	101	24	65	65	CD
cord-298458-p7rvupjo	101	25	)	)	-RRB-
cord-298458-p7rvupjo	101	26	.	.	.
cord-298458-p7rvupjo	102	1	Similarly	similarly	RB
cord-298458-p7rvupjo	102	2	,	,	,
cord-298458-p7rvupjo	102	3	RSV	RSV	NNP
cord-298458-p7rvupjo	102	4	-	-	HYPH
cord-298458-p7rvupjo	102	5	specific	specific	JJ
cord-298458-p7rvupjo	102	6	TRM	TRM	NNP
cord-298458-p7rvupjo	102	7	expressing	express	VBG
cord-298458-p7rvupjo	102	8	both	both	CC
cord-298458-p7rvupjo	102	9	CD69	CD69	NNP
cord-298458-p7rvupjo	102	10	and	and	CC
cord-298458-p7rvupjo	102	11	CD103	CD103	NNP
cord-298458-p7rvupjo	102	12	were	be	VBD
cord-298458-p7rvupjo	102	13	identified	identify	VBN
cord-298458-p7rvupjo	102	14	in	in	IN
cord-298458-p7rvupjo	102	15	the	the	DT
cord-298458-p7rvupjo	102	16	human	human	JJ
cord-298458-p7rvupjo	102	17	BAL	bal	NN
cord-298458-p7rvupjo	102	18	but	but	CC
cord-298458-p7rvupjo	102	19	were	be	VBD
cord-298458-p7rvupjo	102	20	not	not	RB
cord-298458-p7rvupjo	102	21	present	present	JJ
cord-298458-p7rvupjo	102	22	in	in	IN
cord-298458-p7rvupjo	102	23	the	the	DT
cord-298458-p7rvupjo	102	24	peripheral	peripheral	JJ
cord-298458-p7rvupjo	102	25	blood	blood	NN
cord-298458-p7rvupjo	102	26	(	(	-LRB-
cord-298458-p7rvupjo	102	27	49	49	CD
cord-298458-p7rvupjo	102	28	)	)	-RRB-
cord-298458-p7rvupjo	102	29	.	.	.
cord-298458-p7rvupjo	103	1	Following	follow	VBG
cord-298458-p7rvupjo	103	2	secondary	secondary	JJ
cord-298458-p7rvupjo	103	3	viral	viral	JJ
cord-298458-p7rvupjo	103	4	infection	infection	NN
cord-298458-p7rvupjo	103	5	,	,	,
cord-298458-p7rvupjo	103	6	TRM	TRM	NNP
cord-298458-p7rvupjo	103	7	expand	expand	VBP
cord-298458-p7rvupjo	103	8	prior	prior	RB
cord-298458-p7rvupjo	103	9	to	to	IN
cord-298458-p7rvupjo	103	10	the	the	DT
cord-298458-p7rvupjo	103	11	recruitment	recruitment	NN
cord-298458-p7rvupjo	103	12	of	of	IN
cord-298458-p7rvupjo	103	13	circulating	circulate	VBG
cord-298458-p7rvupjo	103	14	memory	memory	NN
cord-298458-p7rvupjo	103	15	CD8	CD8	NNP
cord-298458-p7rvupjo	103	16	T	T	NNP
cord-298458-p7rvupjo	103	17	cell	cell	NN
cord-298458-p7rvupjo	103	18	populations	population	NNS
cord-298458-p7rvupjo	103	19	from	from	IN
cord-298458-p7rvupjo	103	20	the	the	DT
cord-298458-p7rvupjo	103	21	peripheral	peripheral	JJ
cord-298458-p7rvupjo	103	22	blood	blood	NN
cord-298458-p7rvupjo	103	23	and	and	CC
cord-298458-p7rvupjo	103	24	rapidly	rapidly	RB
cord-298458-p7rvupjo	103	25	produce	produce	VB
cord-298458-p7rvupjo	103	26	IFN	IFN	NNP
cord-298458-p7rvupjo	103	27	-	-	HYPH
cord-298458-p7rvupjo	103	28	γ	γ	NNP
cord-298458-p7rvupjo	103	29	(	(	-LRB-
cord-298458-p7rvupjo	103	30	60	60	CD
cord-298458-p7rvupjo	103	31	,	,	,
cord-298458-p7rvupjo	103	32	66	66	CD
cord-298458-p7rvupjo	103	33	)	)	-RRB-
cord-298458-p7rvupjo	103	34	.	.	.
cord-298458-p7rvupjo	104	1	Thus	thus	RB
cord-298458-p7rvupjo	104	2	,	,	,
cord-298458-p7rvupjo	104	3	TRM	TRM	NNP
cord-298458-p7rvupjo	104	4	provide	provide	VBP
cord-298458-p7rvupjo	104	5	a	a	DT
cord-298458-p7rvupjo	104	6	crucial	crucial	JJ
cord-298458-p7rvupjo	104	7	first	first	JJ
cord-298458-p7rvupjo	104	8	-	-	HYPH
cord-298458-p7rvupjo	104	9	line	line	NN
cord-298458-p7rvupjo	104	10	of	of	IN
cord-298458-p7rvupjo	104	11	defense	defense	NN
cord-298458-p7rvupjo	104	12	for	for	IN
cord-298458-p7rvupjo	104	13	protecting	protect	VBG
cord-298458-p7rvupjo	104	14	the	the	DT
cord-298458-p7rvupjo	104	15	host	host	NN
cord-298458-p7rvupjo	104	16	from	from	IN
cord-298458-p7rvupjo	104	17	re	re	NN
cord-298458-p7rvupjo	104	18	-	-	NN
cord-298458-p7rvupjo	104	19	infection	infection	NN
cord-298458-p7rvupjo	104	20	with	with	IN
cord-298458-p7rvupjo	104	21	a	a	DT
cord-298458-p7rvupjo	104	22	respiratory	respiratory	JJ
cord-298458-p7rvupjo	104	23	virus	virus	NN
cord-298458-p7rvupjo	104	24	.	.	.
cord-298458-p7rvupjo	105	1	However	however	RB
cord-298458-p7rvupjo	105	2	,	,	,
cord-298458-p7rvupjo	105	3	in	in	IN
cord-298458-p7rvupjo	105	4	contrast	contrast	NN
cord-298458-p7rvupjo	105	5	to	to	IN
cord-298458-p7rvupjo	105	6	other	other	JJ
cord-298458-p7rvupjo	105	7	memory	memory	NN
cord-298458-p7rvupjo	105	8	CD8	CD8	NNP
cord-298458-p7rvupjo	105	9	T	T	NNP
cord-298458-p7rvupjo	105	10	cell	cell	NN
cord-298458-p7rvupjo	105	11	subsets	subset	NNS
cord-298458-p7rvupjo	105	12	that	that	WDT
cord-298458-p7rvupjo	105	13	remain	remain	VBP
cord-298458-p7rvupjo	105	14	stable	stable	JJ
cord-298458-p7rvupjo	105	15	for	for	IN
cord-298458-p7rvupjo	105	16	long	long	JJ
cord-298458-p7rvupjo	105	17	periods	period	NNS
cord-298458-p7rvupjo	105	18	of	of	IN
cord-298458-p7rvupjo	105	19	time	time	NN
cord-298458-p7rvupjo	105	20	,	,	,
cord-298458-p7rvupjo	105	21	IAVspecific	IAVspecific	NNP
cord-298458-p7rvupjo	105	22	TRM	TRM	NNP
cord-298458-p7rvupjo	105	23	exhibit	exhibit	NN
cord-298458-p7rvupjo	105	24	limited	limited	JJ
cord-298458-p7rvupjo	105	25	longevity	longevity	NN
cord-298458-p7rvupjo	105	26	and	and	CC
cord-298458-p7rvupjo	105	27	enhanced	enhance	VBN
cord-298458-p7rvupjo	105	28	apoptosis	apoptosis	NN
cord-298458-p7rvupjo	105	29	with	with	IN
cord-298458-p7rvupjo	105	30	time	time	NN
cord-298458-p7rvupjo	105	31	following	follow	VBG
cord-298458-p7rvupjo	105	32	infection	infection	NN
cord-298458-p7rvupjo	105	33	(	(	-LRB-
cord-298458-p7rvupjo	105	34	66	66	CD
cord-298458-p7rvupjo	105	35	,	,	,
cord-298458-p7rvupjo	105	36	80	80	CD
cord-298458-p7rvupjo	105	37	)	)	-RRB-
cord-298458-p7rvupjo	105	38	.	.	.
cord-298458-p7rvupjo	106	1	The	the	DT
cord-298458-p7rvupjo	106	2	loss	loss	NN
cord-298458-p7rvupjo	106	3	of	of	IN
cord-298458-p7rvupjo	106	4	IAV	iav	NN
cord-298458-p7rvupjo	106	5	-	-	HYPH
cord-298458-p7rvupjo	106	6	specific	specific	JJ
cord-298458-p7rvupjo	106	7	TRM	TRM	NNP
cord-298458-p7rvupjo	106	8	corresponds	correspond	VBZ
cord-298458-p7rvupjo	106	9	to	to	IN
cord-298458-p7rvupjo	106	10	an	an	DT
cord-298458-p7rvupjo	106	11	increase	increase	NN
cord-298458-p7rvupjo	106	12	in	in	IN
cord-298458-p7rvupjo	106	13	viral	viral	JJ
cord-298458-p7rvupjo	106	14	titers	titer	NNS
cord-298458-p7rvupjo	106	15	and	and	CC
cord-298458-p7rvupjo	106	16	weight	weight	NN
cord-298458-p7rvupjo	106	17	loss	loss	NN
cord-298458-p7rvupjo	106	18	following	follow	VBG
cord-298458-p7rvupjo	106	19	a	a	DT
cord-298458-p7rvupjo	106	20	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	106	21	IAV	IAV	NNP
cord-298458-p7rvupjo	106	22	infection	infection	NN
cord-298458-p7rvupjo	106	23	(	(	-LRB-
cord-298458-p7rvupjo	106	24	66	66	CD
cord-298458-p7rvupjo	106	25	,	,	,
cord-298458-p7rvupjo	106	26	80	80	CD
cord-298458-p7rvupjo	106	27	)	)	-RRB-
cord-298458-p7rvupjo	106	28	.	.	.
cord-298458-p7rvupjo	107	1	Interestingly	interestingly	RB
cord-298458-p7rvupjo	107	2	,	,	,
cord-298458-p7rvupjo	107	3	infant	infant	NN
cord-298458-p7rvupjo	107	4	mice	mouse	NNS
cord-298458-p7rvupjo	107	5	generate	generate	VBP
cord-298458-p7rvupjo	107	6	fewer	few	JJR
cord-298458-p7rvupjo	107	7	lung	lung	NN
cord-298458-p7rvupjo	107	8	TRM	trm	NN
cord-298458-p7rvupjo	107	9	following	follow	VBG
cord-298458-p7rvupjo	107	10	IAV	IAV	NNP
cord-298458-p7rvupjo	107	11	infection	infection	NN
cord-298458-p7rvupjo	107	12	or	or	CC
cord-298458-p7rvupjo	107	13	vaccination	vaccination	NN
cord-298458-p7rvupjo	107	14	and	and	CC
cord-298458-p7rvupjo	107	15	exhibit	exhibit	NN
cord-298458-p7rvupjo	107	16	reduced	reduce	VBN
cord-298458-p7rvupjo	107	17	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	107	18	protection	protection	NN
cord-298458-p7rvupjo	107	19	compared	compare	VBN
cord-298458-p7rvupjo	107	20	to	to	IN
cord-298458-p7rvupjo	107	21	mice	mouse	NNS
cord-298458-p7rvupjo	107	22	initially	initially	RB
cord-298458-p7rvupjo	107	23	infected	infect	VBN
cord-298458-p7rvupjo	107	24	as	as	IN
cord-298458-p7rvupjo	107	25	adults	adult	NNS
cord-298458-p7rvupjo	107	26	(	(	-LRB-
cord-298458-p7rvupjo	107	27	79	79	CD
cord-298458-p7rvupjo	107	28	)	)	-RRB-
cord-298458-p7rvupjo	107	29	.	.	.
cord-298458-p7rvupjo	108	1	Given	give	VBN
cord-298458-p7rvupjo	108	2	the	the	DT
cord-298458-p7rvupjo	108	3	role	role	NN
cord-298458-p7rvupjo	108	4	of	of	IN
cord-298458-p7rvupjo	108	5	lung	lung	NN
cord-298458-p7rvupjo	108	6	TRM	TRM	NNP
cord-298458-p7rvupjo	108	7	in	in	IN
cord-298458-p7rvupjo	108	8	providing	provide	VBG
cord-298458-p7rvupjo	108	9	protection	protection	NN
cord-298458-p7rvupjo	108	10	against	against	IN
cord-298458-p7rvupjo	108	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	108	12	virus	virus	NN
cord-298458-p7rvupjo	108	13	infections	infection	NNS
cord-298458-p7rvupjo	108	14	,	,	,
cord-298458-p7rvupjo	108	15	identifying	identify	VBG
cord-298458-p7rvupjo	108	16	strategies	strategy	NNS
cord-298458-p7rvupjo	108	17	to	to	TO
cord-298458-p7rvupjo	108	18	promote	promote	VB
cord-298458-p7rvupjo	108	19	the	the	DT
cord-298458-p7rvupjo	108	20	generation	generation	NN
cord-298458-p7rvupjo	108	21	of	of	IN
cord-298458-p7rvupjo	108	22	long	long	RB
cord-298458-p7rvupjo	108	23	-	-	HYPH
cord-298458-p7rvupjo	108	24	lived	live	VBN
cord-298458-p7rvupjo	108	25	TRM	TRM	NNP
cord-298458-p7rvupjo	108	26	will	will	MD
cord-298458-p7rvupjo	108	27	be	be	VB
cord-298458-p7rvupjo	108	28	critical	critical	JJ
cord-298458-p7rvupjo	108	29	for	for	IN
cord-298458-p7rvupjo	108	30	future	future	JJ
cord-298458-p7rvupjo	108	31	vaccines	vaccine	NNS
cord-298458-p7rvupjo	108	32	,	,	,
cord-298458-p7rvupjo	108	33	particularly	particularly	RB
cord-298458-p7rvupjo	108	34	for	for	IN
cord-298458-p7rvupjo	108	35	infant	infant	NN
cord-298458-p7rvupjo	108	36	populations	population	NNS
cord-298458-p7rvupjo	108	37	.	.	.
cord-298458-p7rvupjo	109	1	It	-PRON-	PRP
cord-298458-p7rvupjo	109	2	has	have	VBZ
cord-298458-p7rvupjo	109	3	been	be	VBN
cord-298458-p7rvupjo	109	4	well	well	RB
cord-298458-p7rvupjo	109	5	established	establish	VBN
cord-298458-p7rvupjo	109	6	that	that	IN
cord-298458-p7rvupjo	109	7	CD8	CD8	NNP
cord-298458-p7rvupjo	109	8	T	T	NNP
cord-298458-p7rvupjo	109	9	cells	cell	NNS
cord-298458-p7rvupjo	109	10	are	be	VBP
cord-298458-p7rvupjo	109	11	critical	critical	JJ
cord-298458-p7rvupjo	109	12	for	for	IN
cord-298458-p7rvupjo	109	13	viral	viral	JJ
cord-298458-p7rvupjo	109	14	clearance	clearance	NN
cord-298458-p7rvupjo	109	15	following	follow	VBG
cord-298458-p7rvupjo	109	16	an	an	DT
cord-298458-p7rvupjo	109	17	acute	acute	JJ
cord-298458-p7rvupjo	109	18	respiratory	respiratory	JJ
cord-298458-p7rvupjo	109	19	virus	virus	NN
cord-298458-p7rvupjo	109	20	infection	infection	NN
cord-298458-p7rvupjo	109	21	in	in	IN
cord-298458-p7rvupjo	109	22	mice	mouse	NNS
cord-298458-p7rvupjo	109	23	.	.	.
cord-298458-p7rvupjo	110	1	Adoptive	adoptive	JJ
cord-298458-p7rvupjo	110	2	transfer	transfer	NN
cord-298458-p7rvupjo	110	3	of	of	IN
cord-298458-p7rvupjo	110	4	CD8	CD8	NNP
cord-298458-p7rvupjo	110	5	T	T	NNP
cord-298458-p7rvupjo	110	6	cell	cell	NN
cord-298458-p7rvupjo	110	7	clones	clone	NNS
cord-298458-p7rvupjo	110	8	resulted	result	VBD
cord-298458-p7rvupjo	110	9	in	in	IN
cord-298458-p7rvupjo	110	10	significantly	significantly	RB
cord-298458-p7rvupjo	110	11	reduced	reduce	VBN
cord-298458-p7rvupjo	110	12	viral	viral	JJ
cord-298458-p7rvupjo	110	13	titers	titer	NNS
cord-298458-p7rvupjo	110	14	in	in	IN
cord-298458-p7rvupjo	110	15	the	the	DT
cord-298458-p7rvupjo	110	16	lung	lung	NN
cord-298458-p7rvupjo	110	17	following	follow	VBG
cord-298458-p7rvupjo	110	18	RSV	RSV	NNP
cord-298458-p7rvupjo	110	19	,	,	,
cord-298458-p7rvupjo	110	20	IAV	IAV	NNP
cord-298458-p7rvupjo	110	21	,	,	,
cord-298458-p7rvupjo	110	22	or	or	CC
cord-298458-p7rvupjo	110	23	HMPV	hmpv	NN
cord-298458-p7rvupjo	110	24	infections	infection	NNS
cord-298458-p7rvupjo	110	25	(	(	-LRB-
cord-298458-p7rvupjo	110	26	25	25	CD
cord-298458-p7rvupjo	110	27	,	,	,
cord-298458-p7rvupjo	110	28	27	27	CD
cord-298458-p7rvupjo	110	29	,	,	,
cord-298458-p7rvupjo	110	30	(	(	-LRB-
cord-298458-p7rvupjo	110	31	81	81	CD
cord-298458-p7rvupjo	110	32	)	)	-RRB-
cord-298458-p7rvupjo	110	33	(	(	-LRB-
cord-298458-p7rvupjo	110	34	82	82	CD
cord-298458-p7rvupjo	110	35	)	)	-RRB-
cord-298458-p7rvupjo	110	36	(	(	-LRB-
cord-298458-p7rvupjo	110	37	83	83	CD
cord-298458-p7rvupjo	110	38	)	)	-RRB-
cord-298458-p7rvupjo	110	39	(	(	-LRB-
cord-298458-p7rvupjo	110	40	84	84	CD
cord-298458-p7rvupjo	110	41	)	)	-RRB-
cord-298458-p7rvupjo	110	42	.	.	.
cord-298458-p7rvupjo	111	1	Similarly	similarly	RB
cord-298458-p7rvupjo	111	2	,	,	,
cord-298458-p7rvupjo	111	3	the	the	DT
cord-298458-p7rvupjo	111	4	transfer	transfer	NN
cord-298458-p7rvupjo	111	5	of	of	IN
cord-298458-p7rvupjo	111	6	either	either	CC
cord-298458-p7rvupjo	111	7	RSV	RSV	NNP
cord-298458-p7rvupjo	111	8	-	-	:
cord-298458-p7rvupjo	111	9	or	or	CC
cord-298458-p7rvupjo	111	10	IAV	IAV	NNP
cord-298458-p7rvupjo	111	11	-	-	HYPH
cord-298458-p7rvupjo	111	12	immune	immune	JJ
cord-298458-p7rvupjo	111	13	splenic	splenic	JJ
cord-298458-p7rvupjo	111	14	CD8	CD8	NNP
cord-298458-p7rvupjo	111	15	T	T	NNP
cord-298458-p7rvupjo	111	16	cells	cell	NNS
cord-298458-p7rvupjo	111	17	accelerated	accelerate	VBD
cord-298458-p7rvupjo	111	18	viral	viral	JJ
cord-298458-p7rvupjo	111	19	clearance	clearance	NN
cord-298458-p7rvupjo	111	20	in	in	IN
cord-298458-p7rvupjo	111	21	the	the	DT
cord-298458-p7rvupjo	111	22	lung	lung	NN
cord-298458-p7rvupjo	111	23	following	follow	VBG
cord-298458-p7rvupjo	111	24	infection	infection	NN
cord-298458-p7rvupjo	111	25	(	(	-LRB-
cord-298458-p7rvupjo	111	26	85	85	CD
cord-298458-p7rvupjo	111	27	)	)	-RRB-
cord-298458-p7rvupjo	111	28	(	(	-LRB-
cord-298458-p7rvupjo	111	29	86	86	CD
cord-298458-p7rvupjo	111	30	)	)	-RRB-
cord-298458-p7rvupjo	111	31	(	(	-LRB-
cord-298458-p7rvupjo	111	32	87	87	CD
cord-298458-p7rvupjo	111	33	)	)	-RRB-
cord-298458-p7rvupjo	111	34	(	(	-LRB-
cord-298458-p7rvupjo	111	35	88	88	CD
cord-298458-p7rvupjo	111	36	)	)	-RRB-
cord-298458-p7rvupjo	111	37	(	(	-LRB-
cord-298458-p7rvupjo	111	38	89	89	CD
cord-298458-p7rvupjo	111	39	)	)	-RRB-
cord-298458-p7rvupjo	111	40	.	.	.
cord-298458-p7rvupjo	112	1	Accordingly	accordingly	RB
cord-298458-p7rvupjo	112	2	,	,	,
cord-298458-p7rvupjo	112	3	RSV	RSV	NNP
cord-298458-p7rvupjo	112	4	infection	infection	NN
cord-298458-p7rvupjo	112	5	of	of	IN
cord-298458-p7rvupjo	112	6	mice	mouse	NNS
cord-298458-p7rvupjo	112	7	depleted	deplete	VBN
cord-298458-p7rvupjo	112	8	of	of	IN
cord-298458-p7rvupjo	112	9	CD8	CD8	NNP
cord-298458-p7rvupjo	112	10	T	T	NNP
cord-298458-p7rvupjo	112	11	cells	cell	NNS
cord-298458-p7rvupjo	112	12	resulted	result	VBD
cord-298458-p7rvupjo	112	13	in	in	IN
cord-298458-p7rvupjo	112	14	significantly	significantly	RB
cord-298458-p7rvupjo	112	15	increased	increase	VBN
cord-298458-p7rvupjo	112	16	lung	lung	NN
cord-298458-p7rvupjo	112	17	viral	viral	JJ
cord-298458-p7rvupjo	112	18	titers	titer	NNS
cord-298458-p7rvupjo	112	19	at	at	IN
cord-298458-p7rvupjo	112	20	day	day	NN
cord-298458-p7rvupjo	112	21	7	7	CD
cord-298458-p7rvupjo	112	22	post	post	NN
cord-298458-p7rvupjo	112	23	-	-	NN
cord-298458-p7rvupjo	112	24	infection	infection	NN
cord-298458-p7rvupjo	112	25	,	,	,
cord-298458-p7rvupjo	112	26	although	although	IN
cord-298458-p7rvupjo	112	27	the	the	DT
cord-298458-p7rvupjo	112	28	virus	virus	NN
cord-298458-p7rvupjo	112	29	was	be	VBD
cord-298458-p7rvupjo	112	30	ultimately	ultimately	RB
cord-298458-p7rvupjo	112	31	cleared	clear	VBN
cord-298458-p7rvupjo	112	32	by	by	IN
cord-298458-p7rvupjo	112	33	day	day	NN
cord-298458-p7rvupjo	112	34	11	11	CD
cord-298458-p7rvupjo	112	35	(	(	-LRB-
cord-298458-p7rvupjo	112	36	26	26	CD
cord-298458-p7rvupjo	112	37	)	)	-RRB-
cord-298458-p7rvupjo	112	38	.	.	.
cord-298458-p7rvupjo	113	1	In	in	IN
cord-298458-p7rvupjo	113	2	contrast	contrast	NN
cord-298458-p7rvupjo	113	3	,	,	,
cord-298458-p7rvupjo	113	4	depletion	depletion	NN
cord-298458-p7rvupjo	113	5	of	of	IN
cord-298458-p7rvupjo	113	6	CD8	CD8	NNP
cord-298458-p7rvupjo	113	7	T	T	NNP
cord-298458-p7rvupjo	113	8	cells	cell	NNS
cord-298458-p7rvupjo	113	9	alone	alone	RB
cord-298458-p7rvupjo	113	10	did	do	VBD
cord-298458-p7rvupjo	113	11	not	not	RB
cord-298458-p7rvupjo	113	12	alter	alter	VB
cord-298458-p7rvupjo	113	13	clearance	clearance	NN
cord-298458-p7rvupjo	113	14	of	of	IN
cord-298458-p7rvupjo	113	15	HMPV	HMPV	NNP
cord-298458-p7rvupjo	113	16	(	(	-LRB-
cord-298458-p7rvupjo	113	17	40	40	CD
cord-298458-p7rvupjo	113	18	)	)	-RRB-
cord-298458-p7rvupjo	113	19	.	.	.
cord-298458-p7rvupjo	114	1	Instead	instead	RB
cord-298458-p7rvupjo	114	2	,	,	,
cord-298458-p7rvupjo	114	3	depletion	depletion	NN
cord-298458-p7rvupjo	114	4	of	of	IN
cord-298458-p7rvupjo	114	5	both	both	CC
cord-298458-p7rvupjo	114	6	CD4	CD4	NNP
cord-298458-p7rvupjo	114	7	and	and	CC
cord-298458-p7rvupjo	114	8	CD8	CD8	NNP
cord-298458-p7rvupjo	114	9	T	T	NNP
cord-298458-p7rvupjo	114	10	cells	cell	NNS
cord-298458-p7rvupjo	114	11	together	together	RB
cord-298458-p7rvupjo	114	12	elevated	elevated	JJ
cord-298458-p7rvupjo	114	13	lung	lung	NN
cord-298458-p7rvupjo	114	14	virus	virus	NN
cord-298458-p7rvupjo	114	15	titers	titer	NNS
cord-298458-p7rvupjo	114	16	at	at	IN
cord-298458-p7rvupjo	114	17	day	day	NN
cord-298458-p7rvupjo	114	18	7	7	CD
cord-298458-p7rvupjo	114	19	following	follow	VBG
cord-298458-p7rvupjo	114	20	infection	infection	NN
cord-298458-p7rvupjo	114	21	with	with	IN
cord-298458-p7rvupjo	114	22	HMPV	HMPV	NNP
cord-298458-p7rvupjo	114	23	.	.	.
cord-298458-p7rvupjo	115	1	Importantly	importantly	RB
cord-298458-p7rvupjo	115	2	,	,	,
cord-298458-p7rvupjo	115	3	CD8	CD8	NNP
cord-298458-p7rvupjo	115	4	T	T	NNP
cord-298458-p7rvupjo	115	5	cells	cell	NNS
cord-298458-p7rvupjo	115	6	have	have	VBP
cord-298458-p7rvupjo	115	7	been	be	VBN
cord-298458-p7rvupjo	115	8	shown	show	VBN
cord-298458-p7rvupjo	115	9	to	to	TO
cord-298458-p7rvupjo	115	10	be	be	VB
cord-298458-p7rvupjo	115	11	sufficient	sufficient	JJ
cord-298458-p7rvupjo	115	12	to	to	TO
cord-298458-p7rvupjo	115	13	mediate	mediate	VB
cord-298458-p7rvupjo	115	14	viral	viral	JJ
cord-298458-p7rvupjo	115	15	clearance	clearance	NN
cord-298458-p7rvupjo	115	16	in	in	IN
cord-298458-p7rvupjo	115	17	the	the	DT
cord-298458-p7rvupjo	115	18	lung	lung	NN
cord-298458-p7rvupjo	115	19	following	follow	VBG
cord-298458-p7rvupjo	115	20	acute	acute	JJ
cord-298458-p7rvupjo	115	21	respiratory	respiratory	JJ
cord-298458-p7rvupjo	115	22	infections	infection	NNS
cord-298458-p7rvupjo	115	23	(	(	-LRB-
cord-298458-p7rvupjo	115	24	87	87	CD
cord-298458-p7rvupjo	115	25	,	,	,
cord-298458-p7rvupjo	115	26	88	88	CD
cord-298458-p7rvupjo	115	27	)	)	-RRB-
cord-298458-p7rvupjo	115	28	.	.	.
cord-298458-p7rvupjo	116	1	Athymic	Athymic	NNP
cord-298458-p7rvupjo	116	2	nude	nude	JJ
cord-298458-p7rvupjo	116	3	mice	mouse	NNS
cord-298458-p7rvupjo	116	4	,	,	,
cord-298458-p7rvupjo	116	5	which	which	WDT
cord-298458-p7rvupjo	116	6	lack	lack	VBP
cord-298458-p7rvupjo	116	7	T	T	NNP
cord-298458-p7rvupjo	116	8	cells	cell	NNS
cord-298458-p7rvupjo	116	9	,	,	,
cord-298458-p7rvupjo	116	10	fail	fail	VBP
cord-298458-p7rvupjo	116	11	to	to	TO
cord-298458-p7rvupjo	116	12	clear	clear	VB
cord-298458-p7rvupjo	116	13	either	either	CC
cord-298458-p7rvupjo	116	14	RSV	RSV	NNP
cord-298458-p7rvupjo	116	15	or	or	CC
cord-298458-p7rvupjo	116	16	IAV	IAV	NNP
cord-298458-p7rvupjo	116	17	resulting	result	VBG
cord-298458-p7rvupjo	116	18	in	in	IN
cord-298458-p7rvupjo	116	19	persistent	persistent	JJ
cord-298458-p7rvupjo	116	20	infections	infection	NNS
cord-298458-p7rvupjo	116	21	(	(	-LRB-
cord-298458-p7rvupjo	116	22	87	87	CD
cord-298458-p7rvupjo	116	23	,	,	,
cord-298458-p7rvupjo	116	24	90	90	CD
cord-298458-p7rvupjo	116	25	)	)	-RRB-
cord-298458-p7rvupjo	116	26	.	.	.
cord-298458-p7rvupjo	117	1	However	however	RB
cord-298458-p7rvupjo	117	2	,	,	,
cord-298458-p7rvupjo	117	3	the	the	DT
cord-298458-p7rvupjo	117	4	transfer	transfer	NN
cord-298458-p7rvupjo	117	5	of	of	IN
cord-298458-p7rvupjo	117	6	either	either	CC
cord-298458-p7rvupjo	117	7	RSV	RSV	NNP
cord-298458-p7rvupjo	117	8	-	-	:
cord-298458-p7rvupjo	117	9	or	or	CC
cord-298458-p7rvupjo	117	10	IAV	IAV	NNP
cord-298458-p7rvupjo	117	11	-	-	HYPH
cord-298458-p7rvupjo	117	12	immune	immune	JJ
cord-298458-p7rvupjo	117	13	splenic	splenic	JJ
cord-298458-p7rvupjo	117	14	CD8	CD8	NNP
cord-298458-p7rvupjo	117	15	T	T	NNP
cord-298458-p7rvupjo	117	16	cells	cell	NNS
cord-298458-p7rvupjo	117	17	into	into	IN
cord-298458-p7rvupjo	117	18	athymic	athymic	JJ
cord-298458-p7rvupjo	117	19	mice	mouse	NNS
cord-298458-p7rvupjo	117	20	resulted	result	VBD
cord-298458-p7rvupjo	117	21	in	in	IN
cord-298458-p7rvupjo	117	22	significantly	significantly	RB
cord-298458-p7rvupjo	117	23	reduced	reduce	VBN
cord-298458-p7rvupjo	117	24	lung	lung	NN
cord-298458-p7rvupjo	117	25	viral	viral	JJ
cord-298458-p7rvupjo	117	26	titers	titer	NNS
cord-298458-p7rvupjo	117	27	by	by	IN
cord-298458-p7rvupjo	117	28	day	day	NN
cord-298458-p7rvupjo	117	29	15	15	CD
cord-298458-p7rvupjo	117	30	and	and	CC
cord-298458-p7rvupjo	117	31	21	21	CD
cord-298458-p7rvupjo	117	32	,	,	,
cord-298458-p7rvupjo	117	33	respectively	respectively	RB
cord-298458-p7rvupjo	117	34	(	(	-LRB-
cord-298458-p7rvupjo	117	35	87	87	CD
cord-298458-p7rvupjo	117	36	,	,	,
cord-298458-p7rvupjo	117	37	88	88	CD
cord-298458-p7rvupjo	117	38	)	)	-RRB-
cord-298458-p7rvupjo	117	39	.	.	.
cord-298458-p7rvupjo	118	1	Together	together	RB
cord-298458-p7rvupjo	118	2	,	,	,
cord-298458-p7rvupjo	118	3	these	these	DT
cord-298458-p7rvupjo	118	4	studies	study	NNS
cord-298458-p7rvupjo	118	5	indicate	indicate	VBP
cord-298458-p7rvupjo	118	6	that	that	IN
cord-298458-p7rvupjo	118	7	CD8	CD8	NNP
cord-298458-p7rvupjo	118	8	T	T	NNP
cord-298458-p7rvupjo	118	9	cells	cell	NNS
cord-298458-p7rvupjo	118	10	play	play	VBP
cord-298458-p7rvupjo	118	11	a	a	DT
cord-298458-p7rvupjo	118	12	critical	critical	JJ
cord-298458-p7rvupjo	118	13	role	role	NN
cord-298458-p7rvupjo	118	14	in	in	IN
cord-298458-p7rvupjo	118	15	mediating	mediate	VBG
cord-298458-p7rvupjo	118	16	viral	viral	JJ
cord-298458-p7rvupjo	118	17	clearance	clearance	NN
cord-298458-p7rvupjo	118	18	following	follow	VBG
cord-298458-p7rvupjo	118	19	acute	acute	JJ
cord-298458-p7rvupjo	118	20	respiratory	respiratory	JJ
cord-298458-p7rvupjo	118	21	infections	infection	NNS
cord-298458-p7rvupjo	118	22	in	in	IN
cord-298458-p7rvupjo	118	23	mice	mouse	NNS
cord-298458-p7rvupjo	118	24	.	.	.
cord-298458-p7rvupjo	119	1	Although	although	IN
cord-298458-p7rvupjo	119	2	studies	study	NNS
cord-298458-p7rvupjo	119	3	are	be	VBP
cord-298458-p7rvupjo	119	4	limited	limit	VBN
cord-298458-p7rvupjo	119	5	,	,	,
cord-298458-p7rvupjo	119	6	a	a	DT
cord-298458-p7rvupjo	119	7	role	role	NN
cord-298458-p7rvupjo	119	8	for	for	IN
cord-298458-p7rvupjo	119	9	CD8	CD8	NNP
cord-298458-p7rvupjo	119	10	T	T	NNP
cord-298458-p7rvupjo	119	11	cells	cell	NNS
cord-298458-p7rvupjo	119	12	in	in	IN
cord-298458-p7rvupjo	119	13	the	the	DT
cord-298458-p7rvupjo	119	14	elimination	elimination	NN
cord-298458-p7rvupjo	119	15	of	of	IN
cord-298458-p7rvupjo	119	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	119	17	viruses	virus	NNS
cord-298458-p7rvupjo	119	18	has	have	VBZ
cord-298458-p7rvupjo	119	19	also	also	RB
cord-298458-p7rvupjo	119	20	been	be	VBN
cord-298458-p7rvupjo	119	21	established	establish	VBN
cord-298458-p7rvupjo	119	22	in	in	IN
cord-298458-p7rvupjo	119	23	humans	human	NNS
cord-298458-p7rvupjo	119	24	.	.	.
cord-298458-p7rvupjo	120	1	Early	early	JJ
cord-298458-p7rvupjo	120	2	studies	study	NNS
cord-298458-p7rvupjo	120	3	demonstrated	demonstrate	VBD
cord-298458-p7rvupjo	120	4	that	that	IN
cord-298458-p7rvupjo	120	5	immunocompromised	immunocompromised	JJ
cord-298458-p7rvupjo	120	6	children	child	NNS
cord-298458-p7rvupjo	120	7	with	with	IN
cord-298458-p7rvupjo	120	8	T	T	NNP
cord-298458-p7rvupjo	120	9	cell	cell	NN
cord-298458-p7rvupjo	120	10	defects	defect	NNS
cord-298458-p7rvupjo	120	11	experienced	experience	VBD
cord-298458-p7rvupjo	120	12	prolonged	prolong	VBN
cord-298458-p7rvupjo	120	13	viral	viral	JJ
cord-298458-p7rvupjo	120	14	shedding	shed	VBG
cord-298458-p7rvupjo	120	15	following	follow	VBG
cord-298458-p7rvupjo	120	16	RSV	RSV	NNP
cord-298458-p7rvupjo	120	17	,	,	,
cord-298458-p7rvupjo	120	18	IAV	IAV	NNP
cord-298458-p7rvupjo	120	19	,	,	,
cord-298458-p7rvupjo	120	20	or	or	CC
cord-298458-p7rvupjo	120	21	PIV	PIV	NNP
cord-298458-p7rvupjo	120	22	infections	infection	NNS
cord-298458-p7rvupjo	120	23	compared	compare	VBN
cord-298458-p7rvupjo	120	24	to	to	IN
cord-298458-p7rvupjo	120	25	immunologically	immunologically	RB
cord-298458-p7rvupjo	120	26	normal	normal	JJ
cord-298458-p7rvupjo	120	27	children	child	NNS
cord-298458-p7rvupjo	120	28	(	(	-LRB-
cord-298458-p7rvupjo	120	29	3	3	CD
cord-298458-p7rvupjo	120	30	,	,	,
cord-298458-p7rvupjo	120	31	91	91	CD
cord-298458-p7rvupjo	120	32	,	,	,
cord-298458-p7rvupjo	120	33	92	92	CD
cord-298458-p7rvupjo	120	34	)	)	-RRB-
cord-298458-p7rvupjo	120	35	.	.	.
cord-298458-p7rvupjo	121	1	Following	follow	VBG
cord-298458-p7rvupjo	121	2	bone	bone	NN
cord-298458-p7rvupjo	121	3	marrow	marrow	NN
cord-298458-p7rvupjo	121	4	transplantation	transplantation	NN
cord-298458-p7rvupjo	121	5	of	of	IN
cord-298458-p7rvupjo	121	6	an	an	DT
cord-298458-p7rvupjo	121	7	RSV	RSV	NNP
cord-298458-p7rvupjo	121	8	-	-	HYPH
cord-298458-p7rvupjo	121	9	infected	infect	VBN
cord-298458-p7rvupjo	121	10	child	child	NN
cord-298458-p7rvupjo	121	11	with	with	IN
cord-298458-p7rvupjo	121	12	severe	severe	JJ
cord-298458-p7rvupjo	121	13	combined	combine	VBN
cord-298458-p7rvupjo	121	14	immunodeficiency	immunodeficiency	NN
cord-298458-p7rvupjo	121	15	,	,	,
cord-298458-p7rvupjo	121	16	a	a	DT
cord-298458-p7rvupjo	121	17	marked	mark	VBN
cord-298458-p7rvupjo	121	18	reduction	reduction	NN
cord-298458-p7rvupjo	121	19	in	in	IN
cord-298458-p7rvupjo	121	20	nasal	nasal	JJ
cord-298458-p7rvupjo	121	21	viral	viral	JJ
cord-298458-p7rvupjo	121	22	load	load	NN
cord-298458-p7rvupjo	121	23	was	be	VBD
cord-298458-p7rvupjo	121	24	observed	observe	VBN
cord-298458-p7rvupjo	121	25	that	that	IN
cord-298458-p7rvupjo	121	26	correlated	correlate	VBD
cord-298458-p7rvupjo	121	27	with	with	IN
cord-298458-p7rvupjo	121	28	an	an	DT
cord-298458-p7rvupjo	121	29	elevation	elevation	NN
cord-298458-p7rvupjo	121	30	of	of	IN
cord-298458-p7rvupjo	121	31	CD8	CD8	NNP
cord-298458-p7rvupjo	121	32	T	T	NNP
cord-298458-p7rvupjo	121	33	cell	cell	NN
cord-298458-p7rvupjo	121	34	counts	count	NNS
cord-298458-p7rvupjo	121	35	(	(	-LRB-
cord-298458-p7rvupjo	121	36	92	92	CD
cord-298458-p7rvupjo	121	37	)	)	-RRB-
cord-298458-p7rvupjo	121	38	.	.	.
cord-298458-p7rvupjo	122	1	Recently	recently	RB
cord-298458-p7rvupjo	122	2	,	,	,
cord-298458-p7rvupjo	122	3	it	-PRON-	PRP
cord-298458-p7rvupjo	122	4	has	have	VBZ
cord-298458-p7rvupjo	122	5	been	be	VBN
cord-298458-p7rvupjo	122	6	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	122	7	that	that	IN
cord-298458-p7rvupjo	122	8	the	the	DT
cord-298458-p7rvupjo	122	9	number	number	NN
cord-298458-p7rvupjo	122	10	of	of	IN
cord-298458-p7rvupjo	122	11	pre	pre	JJ
cord-298458-p7rvupjo	122	12	-	-	JJ
cord-298458-p7rvupjo	122	13	existing	existing	JJ
cord-298458-p7rvupjo	122	14	virus	virus	NN
cord-298458-p7rvupjo	122	15	-	-	HYPH
cord-298458-p7rvupjo	122	16	specific	specific	JJ
cord-298458-p7rvupjo	122	17	CD8	CD8	NNP
cord-298458-p7rvupjo	122	18	T	T	NNP
cord-298458-p7rvupjo	122	19	cells	cell	NNS
cord-298458-p7rvupjo	122	20	in	in	IN
cord-298458-p7rvupjo	122	21	the	the	DT
cord-298458-p7rvupjo	122	22	airway	airway	NN
cord-298458-p7rvupjo	122	23	of	of	IN
cord-298458-p7rvupjo	122	24	adults	adult	NNS
cord-298458-p7rvupjo	122	25	experimentally	experimentally	RB
cord-298458-p7rvupjo	122	26	infected	infect	VBN
cord-298458-p7rvupjo	122	27	with	with	IN
cord-298458-p7rvupjo	122	28	RSV	RSV	NNP
cord-298458-p7rvupjo	122	29	correlated	correlate	VBN
cord-298458-p7rvupjo	122	30	with	with	IN
cord-298458-p7rvupjo	122	31	reduced	reduce	VBN
cord-298458-p7rvupjo	122	32	overall	overall	JJ
cord-298458-p7rvupjo	122	33	viral	viral	JJ
cord-298458-p7rvupjo	122	34	load	load	NN
cord-298458-p7rvupjo	122	35	in	in	IN
cord-298458-p7rvupjo	122	36	the	the	DT
cord-298458-p7rvupjo	122	37	nasal	nasal	NN
cord-298458-p7rvupjo	122	38	cavity	cavity	NN
cord-298458-p7rvupjo	122	39	and	and	CC
cord-298458-p7rvupjo	122	40	bronchial	bronchial	JJ
cord-298458-p7rvupjo	122	41	brushings	brushing	NNS
cord-298458-p7rvupjo	122	42	(	(	-LRB-
cord-298458-p7rvupjo	122	43	49	49	CD
cord-298458-p7rvupjo	122	44	)	)	-RRB-
cord-298458-p7rvupjo	122	45	.	.	.
cord-298458-p7rvupjo	123	1	In	in	IN
cord-298458-p7rvupjo	123	2	addition	addition	NN
cord-298458-p7rvupjo	123	3	to	to	TO
cord-298458-p7rvupjo	123	4	pre	pre	VB
cord-298458-p7rvupjo	123	5	-	-	JJ
cord-298458-p7rvupjo	123	6	existing	existing	JJ
cord-298458-p7rvupjo	123	7	CD8	CD8	NNP
cord-298458-p7rvupjo	123	8	T	T	NNP
cord-298458-p7rvupjo	123	9	cell	cell	NN
cord-298458-p7rvupjo	123	10	numbers	number	NNS
cord-298458-p7rvupjo	123	11	,	,	,
cord-298458-p7rvupjo	123	12	CD8	CD8	NNP
cord-298458-p7rvupjo	123	13	T	T	NNP
cord-298458-p7rvupjo	123	14	cell	cell	NN
cord-298458-p7rvupjo	123	15	effector	effector	NN
cord-298458-p7rvupjo	123	16	functions	function	NNS
cord-298458-p7rvupjo	123	17	also	also	RB
cord-298458-p7rvupjo	123	18	correlate	correlate	VBP
cord-298458-p7rvupjo	123	19	with	with	IN
cord-298458-p7rvupjo	123	20	reduced	reduce	VBN
cord-298458-p7rvupjo	123	21	viral	viral	JJ
cord-298458-p7rvupjo	123	22	load	load	NN
cord-298458-p7rvupjo	123	23	.	.	.
cord-298458-p7rvupjo	124	1	CD8	CD8	NNP
cord-298458-p7rvupjo	124	2	T	T	NNP
cord-298458-p7rvupjo	124	3	cell	cell	NN
cord-298458-p7rvupjo	124	4	target	target	NN
cord-298458-p7rvupjo	124	5	cell	cell	NN
cord-298458-p7rvupjo	124	6	lysis	lysis	NN
cord-298458-p7rvupjo	124	7	activity	activity	NN
cord-298458-p7rvupjo	124	8	measured	measure	VBN
cord-298458-p7rvupjo	124	9	by	by	IN
cord-298458-p7rvupjo	124	10	chromiumrelease	chromiumrelease	NNP
cord-298458-p7rvupjo	124	11	assay	assay	NNP
cord-298458-p7rvupjo	124	12	correlated	correlate	VBN
cord-298458-p7rvupjo	124	13	with	with	IN
cord-298458-p7rvupjo	124	14	a	a	DT
cord-298458-p7rvupjo	124	15	lack	lack	NN
cord-298458-p7rvupjo	124	16	of	of	IN
cord-298458-p7rvupjo	124	17	viral	viral	JJ
cord-298458-p7rvupjo	124	18	shedding	shedding	NN
cord-298458-p7rvupjo	124	19	in	in	IN
cord-298458-p7rvupjo	124	20	the	the	DT
cord-298458-p7rvupjo	124	21	nasal	nasal	NN
cord-298458-p7rvupjo	124	22	washes	wash	NNS
cord-298458-p7rvupjo	124	23	of	of	IN
cord-298458-p7rvupjo	124	24	adults	adult	NNS
cord-298458-p7rvupjo	124	25	experimentally	experimentally	RB
cord-298458-p7rvupjo	124	26	infected	infect	VBN
cord-298458-p7rvupjo	124	27	with	with	IN
cord-298458-p7rvupjo	124	28	H1N1	H1N1	NNP
cord-298458-p7rvupjo	124	29	IAV	IAV	NNP
cord-298458-p7rvupjo	124	30	(	(	-LRB-
cord-298458-p7rvupjo	124	31	93	93	CD
cord-298458-p7rvupjo	124	32	)	)	-RRB-
cord-298458-p7rvupjo	124	33	.	.	.
cord-298458-p7rvupjo	125	1	Additionally	additionally	RB
cord-298458-p7rvupjo	125	2	,	,	,
cord-298458-p7rvupjo	125	3	individuals	individual	NNS
cord-298458-p7rvupjo	125	4	with	with	IN
cord-298458-p7rvupjo	125	5	the	the	DT
cord-298458-p7rvupjo	125	6	lowest	low	JJS
cord-298458-p7rvupjo	125	7	frequencies	frequency	NNS
cord-298458-p7rvupjo	125	8	of	of	IN
cord-298458-p7rvupjo	125	9	IFN	IFN	NNP
cord-298458-p7rvupjo	125	10	-	-	HYPH
cord-298458-p7rvupjo	125	11	γ	γ	NNP
cord-298458-p7rvupjo	125	12	+	+	SYM
cord-298458-p7rvupjo	125	13	CD8	CD8	NNP
cord-298458-p7rvupjo	125	14	T	T	NNP
cord-298458-p7rvupjo	125	15	cells	cell	NNS
cord-298458-p7rvupjo	125	16	exhibited	exhibit	VBD
cord-298458-p7rvupjo	125	17	the	the	DT
cord-298458-p7rvupjo	125	18	highest	high	JJS
cord-298458-p7rvupjo	125	19	viral	viral	JJ
cord-298458-p7rvupjo	125	20	titers	titer	NNS
cord-298458-p7rvupjo	125	21	following	follow	VBG
cord-298458-p7rvupjo	125	22	natural	natural	JJ
cord-298458-p7rvupjo	125	23	H7N9	H7N9	NNP
cord-298458-p7rvupjo	125	24	IAV	IAV	NNP
cord-298458-p7rvupjo	125	25	infection	infection	NN
cord-298458-p7rvupjo	125	26	(	(	-LRB-
cord-298458-p7rvupjo	125	27	94	94	CD
cord-298458-p7rvupjo	125	28	)	)	-RRB-
cord-298458-p7rvupjo	125	29	.	.	.
cord-298458-p7rvupjo	126	1	These	these	DT
cord-298458-p7rvupjo	126	2	studies	study	NNS
cord-298458-p7rvupjo	126	3	support	support	VBP
cord-298458-p7rvupjo	126	4	the	the	DT
cord-298458-p7rvupjo	126	5	role	role	NN
cord-298458-p7rvupjo	126	6	of	of	IN
cord-298458-p7rvupjo	126	7	CD8	CD8	NNP
cord-298458-p7rvupjo	126	8	T	T	NNP
cord-298458-p7rvupjo	126	9	cells	cell	NNS
cord-298458-p7rvupjo	126	10	in	in	IN
cord-298458-p7rvupjo	126	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	126	12	virus	virus	NN
cord-298458-p7rvupjo	126	13	clearance	clearance	NN
cord-298458-p7rvupjo	126	14	in	in	IN
cord-298458-p7rvupjo	126	15	humans	human	NNS
cord-298458-p7rvupjo	126	16	,	,	,
cord-298458-p7rvupjo	126	17	consistent	consistent	JJ
cord-298458-p7rvupjo	126	18	with	with	IN
cord-298458-p7rvupjo	126	19	the	the	DT
cord-298458-p7rvupjo	126	20	numerous	numerous	JJ
cord-298458-p7rvupjo	126	21	murine	murine	JJ
cord-298458-p7rvupjo	126	22	studies	study	NNS
cord-298458-p7rvupjo	126	23	.	.	.
cord-298458-p7rvupjo	127	1	CD8	CD8	NNP
cord-298458-p7rvupjo	127	2	T	T	NNP
cord-298458-p7rvupjo	127	3	cells	cell	NNS
cord-298458-p7rvupjo	127	4	mediate	mediate	VBP
cord-298458-p7rvupjo	127	5	viral	viral	JJ
cord-298458-p7rvupjo	127	6	clearance	clearance	NN
cord-298458-p7rvupjo	127	7	by	by	IN
cord-298458-p7rvupjo	127	8	utilizing	utilize	VBG
cord-298458-p7rvupjo	127	9	a	a	DT
cord-298458-p7rvupjo	127	10	variety	variety	NN
cord-298458-p7rvupjo	127	11	of	of	IN
cord-298458-p7rvupjo	127	12	effector	effector	NN
cord-298458-p7rvupjo	127	13	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	127	14	to	to	TO
cord-298458-p7rvupjo	127	15	induce	induce	VB
cord-298458-p7rvupjo	127	16	the	the	DT
cord-298458-p7rvupjo	127	17	apoptosis	apoptosis	NN
cord-298458-p7rvupjo	127	18	of	of	IN
cord-298458-p7rvupjo	127	19	virus	virus	NN
cord-298458-p7rvupjo	127	20	-	-	HYPH
cord-298458-p7rvupjo	127	21	infected	infect	VBN
cord-298458-p7rvupjo	127	22	cells	cell	NNS
cord-298458-p7rvupjo	127	23	(	(	-LRB-
cord-298458-p7rvupjo	127	24	95	95	CD
cord-298458-p7rvupjo	127	25	)	)	-RRB-
cord-298458-p7rvupjo	127	26	.	.	.
cord-298458-p7rvupjo	128	1	CD8	CD8	NNP
cord-298458-p7rvupjo	128	2	T	T	NNP
cord-298458-p7rvupjo	128	3	cells	cell	NNS
cord-298458-p7rvupjo	128	4	can	can	MD
cord-298458-p7rvupjo	128	5	use	use	VB
cord-298458-p7rvupjo	128	6	direct	direct	JJ
cord-298458-p7rvupjo	128	7	cell	cell	NN
cord-298458-p7rvupjo	128	8	-	-	HYPH
cord-298458-p7rvupjo	128	9	cell	cell	NN
cord-298458-p7rvupjo	128	10	contact	contact	NN
cord-298458-p7rvupjo	128	11	to	to	TO
cord-298458-p7rvupjo	128	12	eliminate	eliminate	VB
cord-298458-p7rvupjo	128	13	target	target	NN
cord-298458-p7rvupjo	128	14	cells	cell	NNS
cord-298458-p7rvupjo	128	15	through	through	IN
cord-298458-p7rvupjo	128	16	the	the	DT
cord-298458-p7rvupjo	128	17	interactions	interaction	NNS
cord-298458-p7rvupjo	128	18	of	of	IN
cord-298458-p7rvupjo	128	19	surface	surface	NN
cord-298458-p7rvupjo	128	20	molecules	molecule	NNS
cord-298458-p7rvupjo	128	21	such	such	JJ
cord-298458-p7rvupjo	128	22	as	as	IN
cord-298458-p7rvupjo	128	23	Fas	Fas	NNP
cord-298458-p7rvupjo	128	24	(	(	-LRB-
cord-298458-p7rvupjo	128	25	CD95	CD95	NNP
cord-298458-p7rvupjo	128	26	)	)	-RRB-
cord-298458-p7rvupjo	128	27	and	and	CC
cord-298458-p7rvupjo	128	28	FasL	FasL	NNP
cord-298458-p7rvupjo	128	29	(	(	-LRB-
cord-298458-p7rvupjo	128	30	CD95L	cd95l	NN
cord-298458-p7rvupjo	128	31	)	)	-RRB-
cord-298458-p7rvupjo	128	32	.	.	.
cord-298458-p7rvupjo	129	1	Additionally	additionally	RB
cord-298458-p7rvupjo	129	2	,	,	,
cord-298458-p7rvupjo	129	3	TRAIL	TRAIL	NNP
cord-298458-p7rvupjo	129	4	expressed	express	VBD
cord-298458-p7rvupjo	129	5	on	on	IN
cord-298458-p7rvupjo	129	6	CD8	CD8	NNP
cord-298458-p7rvupjo	129	7	T	T	NNP
cord-298458-p7rvupjo	129	8	cells	cell	NNS
cord-298458-p7rvupjo	129	9	can	can	MD
cord-298458-p7rvupjo	129	10	interact	interact	VB
cord-298458-p7rvupjo	129	11	with	with	IN
cord-298458-p7rvupjo	129	12	its	-PRON-	PRP$
cord-298458-p7rvupjo	129	13	receptors	receptor	NNS
cord-298458-p7rvupjo	129	14	DR4	dr4	NN
cord-298458-p7rvupjo	129	15	and/or	and/or	CC
cord-298458-p7rvupjo	129	16	DR5	DR5	NNP
cord-298458-p7rvupjo	129	17	to	to	TO
cord-298458-p7rvupjo	129	18	induce	induce	VB
cord-298458-p7rvupjo	129	19	the	the	DT
cord-298458-p7rvupjo	129	20	destruction	destruction	NN
cord-298458-p7rvupjo	129	21	of	of	IN
cord-298458-p7rvupjo	129	22	infected	infected	JJ
cord-298458-p7rvupjo	129	23	cells	cell	NNS
cord-298458-p7rvupjo	129	24	.	.	.
cord-298458-p7rvupjo	130	1	CD8	CD8	NNP
cord-298458-p7rvupjo	130	2	T	T	NNP
cord-298458-p7rvupjo	130	3	cells	cell	NNS
cord-298458-p7rvupjo	130	4	can	can	MD
cord-298458-p7rvupjo	130	5	also	also	RB
cord-298458-p7rvupjo	130	6	secrete	secrete	VB
cord-298458-p7rvupjo	130	7	perforin	perforin	NNS
cord-298458-p7rvupjo	130	8	and	and	CC
cord-298458-p7rvupjo	130	9	granzymes	granzyme	NNS
cord-298458-p7rvupjo	130	10	to	to	TO
cord-298458-p7rvupjo	130	11	cause	cause	VB
cord-298458-p7rvupjo	130	12	membrane	membrane	NN
cord-298458-p7rvupjo	130	13	pore	pore	NN
cord-298458-p7rvupjo	130	14	formation	formation	NN
cord-298458-p7rvupjo	130	15	and	and	CC
cord-298458-p7rvupjo	130	16	induce	induce	VB
cord-298458-p7rvupjo	130	17	apoptosis	apoptosis	NN
cord-298458-p7rvupjo	130	18	.	.	.
cord-298458-p7rvupjo	131	1	Lastly	lastly	RB
cord-298458-p7rvupjo	131	2	,	,	,
cord-298458-p7rvupjo	131	3	CD8	CD8	NNP
cord-298458-p7rvupjo	131	4	T	T	NNP
cord-298458-p7rvupjo	131	5	cells	cell	NNS
cord-298458-p7rvupjo	131	6	produce	produce	VBP
cord-298458-p7rvupjo	131	7	inflammatory	inflammatory	JJ
cord-298458-p7rvupjo	131	8	cytokines	cytokine	NNS
cord-298458-p7rvupjo	131	9	,	,	,
cord-298458-p7rvupjo	131	10	such	such	JJ
cord-298458-p7rvupjo	131	11	as	as	IN
cord-298458-p7rvupjo	131	12	IFN	IFN	NNP
cord-298458-p7rvupjo	131	13	-	-	HYPH
cord-298458-p7rvupjo	131	14	γ	γ	NNP
cord-298458-p7rvupjo	131	15	and	and	CC
cord-298458-p7rvupjo	131	16	TNF	TNF	NNP
cord-298458-p7rvupjo	131	17	,	,	,
cord-298458-p7rvupjo	131	18	which	which	WDT
cord-298458-p7rvupjo	131	19	may	may	MD
cord-298458-p7rvupjo	131	20	either	either	CC
cord-298458-p7rvupjo	131	21	directly	directly	RB
cord-298458-p7rvupjo	131	22	or	or	CC
cord-298458-p7rvupjo	131	23	indirectly	indirectly	RB
cord-298458-p7rvupjo	131	24	promote	promote	VB
cord-298458-p7rvupjo	131	25	the	the	DT
cord-298458-p7rvupjo	131	26	cell	cell	NN
cord-298458-p7rvupjo	131	27	death	death	NN
cord-298458-p7rvupjo	131	28	of	of	IN
cord-298458-p7rvupjo	131	29	virus	virus	NN
cord-298458-p7rvupjo	131	30	-	-	HYPH
cord-298458-p7rvupjo	131	31	infected	infect	VBN
cord-298458-p7rvupjo	131	32	cells	cell	NNS
cord-298458-p7rvupjo	131	33	.	.	.
cord-298458-p7rvupjo	132	1	While	while	IN
cord-298458-p7rvupjo	132	2	the	the	DT
cord-298458-p7rvupjo	132	3	exact	exact	JJ
cord-298458-p7rvupjo	132	4	mechanism	mechanism	NN
cord-298458-p7rvupjo	132	5	utilized	utilize	VBN
cord-298458-p7rvupjo	132	6	is	be	VBZ
cord-298458-p7rvupjo	132	7	unclear	unclear	JJ
cord-298458-p7rvupjo	132	8	,	,	,
cord-298458-p7rvupjo	132	9	many	many	JJ
cord-298458-p7rvupjo	132	10	of	of	IN
cord-298458-p7rvupjo	132	11	these	these	DT
cord-298458-p7rvupjo	132	12	effector	effector	NN
cord-298458-p7rvupjo	132	13	functions	function	NNS
cord-298458-p7rvupjo	132	14	have	have	VBP
cord-298458-p7rvupjo	132	15	been	be	VBN
cord-298458-p7rvupjo	132	16	associated	associate	VBN
cord-298458-p7rvupjo	132	17	with	with	IN
cord-298458-p7rvupjo	132	18	CD8	CD8	NNP
cord-298458-p7rvupjo	132	19	T	T	NNP
cord-298458-p7rvupjo	132	20	cell	cell	NN
cord-298458-p7rvupjo	132	21	-	-	HYPH
cord-298458-p7rvupjo	132	22	mediated	mediate	VBN
cord-298458-p7rvupjo	132	23	clearance	clearance	NN
cord-298458-p7rvupjo	132	24	of	of	IN
cord-298458-p7rvupjo	132	25	respiratory	respiratory	JJ
cord-298458-p7rvupjo	132	26	viruses	virus	NNS
cord-298458-p7rvupjo	132	27	.	.	.
cord-298458-p7rvupjo	133	1	Fas	Fas	NNP
cord-298458-p7rvupjo	133	2	/	/	SYM
cord-298458-p7rvupjo	133	3	FasL	FasL	NNP
cord-298458-p7rvupjo	133	4	interactions	interaction	NNS
cord-298458-p7rvupjo	133	5	and	and	CC
cord-298458-p7rvupjo	133	6	the	the	DT
cord-298458-p7rvupjo	133	7	perforin	perforin	NNP
cord-298458-p7rvupjo	133	8	pathway	pathway	NN
cord-298458-p7rvupjo	133	9	have	have	VBP
cord-298458-p7rvupjo	133	10	been	be	VBN
cord-298458-p7rvupjo	133	11	established	establish	VBN
cord-298458-p7rvupjo	133	12	as	as	IN
cord-298458-p7rvupjo	133	13	the	the	DT
cord-298458-p7rvupjo	133	14	primary	primary	JJ
cord-298458-p7rvupjo	133	15	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	133	16	by	by	IN
cord-298458-p7rvupjo	133	17	which	which	WDT
cord-298458-p7rvupjo	133	18	CD8	CD8	NNP
cord-298458-p7rvupjo	133	19	T	T	NNP
cord-298458-p7rvupjo	133	20	cells	cell	NNS
cord-298458-p7rvupjo	133	21	eliminate	eliminate	VBP
cord-298458-p7rvupjo	133	22	infected	infected	JJ
cord-298458-p7rvupjo	133	23	cells	cell	NNS
cord-298458-p7rvupjo	133	24	following	follow	VBG
cord-298458-p7rvupjo	133	25	an	an	DT
cord-298458-p7rvupjo	133	26	IAV	IAV	NNP
cord-298458-p7rvupjo	133	27	infection	infection	NN
cord-298458-p7rvupjo	133	28	(	(	-LRB-
cord-298458-p7rvupjo	133	29	96	96	CD
cord-298458-p7rvupjo	133	30	,	,	,
cord-298458-p7rvupjo	133	31	97	97	CD
cord-298458-p7rvupjo	133	32	)	)	-RRB-
cord-298458-p7rvupjo	133	33	.	.	.
cord-298458-p7rvupjo	134	1	Studies	study	NNS
cord-298458-p7rvupjo	134	2	utilizing	utilize	VBG
cord-298458-p7rvupjo	134	3	TRAIL	trail	NN
cord-298458-p7rvupjo	134	4	-	-	HYPH
cord-298458-p7rvupjo	134	5	deficient	deficient	JJ
cord-298458-p7rvupjo	134	6	mice	mouse	NNS
cord-298458-p7rvupjo	134	7	and	and	CC
cord-298458-p7rvupjo	134	8	antibody	antibody	NN
cord-298458-p7rvupjo	134	9	-	-	HYPH
cord-298458-p7rvupjo	134	10	mediated	mediate	VBN
cord-298458-p7rvupjo	134	11	TRAIL	TRAIL	NNP
cord-298458-p7rvupjo	134	12	blockade	blockade	NN
cord-298458-p7rvupjo	134	13	have	have	VBP
cord-298458-p7rvupjo	134	14	also	also	RB
cord-298458-p7rvupjo	134	15	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	134	16	a	a	DT
cord-298458-p7rvupjo	134	17	role	role	NN
cord-298458-p7rvupjo	134	18	for	for	IN
cord-298458-p7rvupjo	134	19	TRAIL	TRAIL	NNP
cord-298458-p7rvupjo	134	20	in	in	IN
cord-298458-p7rvupjo	134	21	CD8	CD8	NNP
cord-298458-p7rvupjo	134	22	T	T	NNP
cord-298458-p7rvupjo	134	23	cell	cell	NN
cord-298458-p7rvupjo	134	24	-	-	HYPH
cord-298458-p7rvupjo	134	25	mediated	mediate	VBN
cord-298458-p7rvupjo	134	26	clearance	clearance	NN
cord-298458-p7rvupjo	134	27	of	of	IN
cord-298458-p7rvupjo	134	28	IAV	IAV	NNP
cord-298458-p7rvupjo	134	29	(	(	-LRB-
cord-298458-p7rvupjo	134	30	98	98	CD
cord-298458-p7rvupjo	134	31	,	,	,
cord-298458-p7rvupjo	134	32	99	99	CD
cord-298458-p7rvupjo	134	33	)	)	-RRB-
cord-298458-p7rvupjo	134	34	.	.	.
cord-298458-p7rvupjo	135	1	Similarly	similarly	RB
cord-298458-p7rvupjo	135	2	,	,	,
cord-298458-p7rvupjo	135	3	Fas/	Fas/	NNP
cord-298458-p7rvupjo	135	4	FasL	FasL	NNP
cord-298458-p7rvupjo	135	5	and	and	CC
cord-298458-p7rvupjo	135	6	perforin	perforin	NNP
cord-298458-p7rvupjo	135	7	pathways	pathway	NNS
cord-298458-p7rvupjo	135	8	have	have	VBP
cord-298458-p7rvupjo	135	9	also	also	RB
cord-298458-p7rvupjo	135	10	been	be	VBN
cord-298458-p7rvupjo	135	11	associated	associate	VBN
cord-298458-p7rvupjo	135	12	with	with	IN
cord-298458-p7rvupjo	135	13	virus	virus	NN
cord-298458-p7rvupjo	135	14	elimination	elimination	NN
cord-298458-p7rvupjo	135	15	following	follow	VBG
cord-298458-p7rvupjo	135	16	RSV	RSV	NNP
cord-298458-p7rvupjo	135	17	infection	infection	NN
cord-298458-p7rvupjo	135	18	.	.	.
cord-298458-p7rvupjo	136	1	Perforin	Perforin	NNP
cord-298458-p7rvupjo	136	2	-	-	HYPH
cord-298458-p7rvupjo	136	3	deficient	deficient	JJ
cord-298458-p7rvupjo	136	4	and	and	CC
cord-298458-p7rvupjo	136	5	FasL	FasL	NNP
cord-298458-p7rvupjo	136	6	-	-	HYPH
cord-298458-p7rvupjo	136	7	deficient	deficient	JJ
cord-298458-p7rvupjo	136	8	gld	gld	NNP
cord-298458-p7rvupjo	136	9	mice	mouse	NNS
cord-298458-p7rvupjo	136	10	exhibit	exhibit	VBP
cord-298458-p7rvupjo	136	11	significantly	significantly	RB
cord-298458-p7rvupjo	136	12	delayed	delay	VBN
cord-298458-p7rvupjo	136	13	viral	viral	JJ
cord-298458-p7rvupjo	136	14	clearance	clearance	NN
cord-298458-p7rvupjo	136	15	(	(	-LRB-
cord-298458-p7rvupjo	136	16	100	100	CD
cord-298458-p7rvupjo	136	17	,	,	,
cord-298458-p7rvupjo	136	18	101	101	CD
cord-298458-p7rvupjo	136	19	)	)	-RRB-
cord-298458-p7rvupjo	136	20	.	.	.
cord-298458-p7rvupjo	137	1	However	however	RB
cord-298458-p7rvupjo	137	2	,	,	,
cord-298458-p7rvupjo	137	3	both	both	DT
cord-298458-p7rvupjo	137	4	perforin	perforin	NN
cord-298458-p7rvupjo	137	5	-	-	HYPH
cord-298458-p7rvupjo	137	6	deficient	deficient	JJ
cord-298458-p7rvupjo	137	7	and	and	CC
cord-298458-p7rvupjo	137	8	gld	gld	NNP
cord-298458-p7rvupjo	137	9	mice	mouse	NNS
cord-298458-p7rvupjo	137	10	achieve	achieve	VBP
cord-298458-p7rvupjo	137	11	complete	complete	JJ
cord-298458-p7rvupjo	137	12	viral	viral	JJ
cord-298458-p7rvupjo	137	13	clearance	clearance	NN
cord-298458-p7rvupjo	137	14	by	by	IN
cord-298458-p7rvupjo	137	15	day	day	NN
cord-298458-p7rvupjo	137	16	10	10	CD
cord-298458-p7rvupjo	137	17	post	post	NN
cord-298458-p7rvupjo	137	18	-	-	NN
cord-298458-p7rvupjo	137	19	infection	infection	NN
cord-298458-p7rvupjo	137	20	,	,	,
cord-298458-p7rvupjo	137	21	suggesting	suggest	VBG
cord-298458-p7rvupjo	137	22	that	that	IN
cord-298458-p7rvupjo	137	23	CD8	CD8	NNP
cord-298458-p7rvupjo	137	24	T	T	NNP
cord-298458-p7rvupjo	137	25	cells	cell	NNS
cord-298458-p7rvupjo	137	26	compensate	compensate	VBP
cord-298458-p7rvupjo	137	27	for	for	IN
cord-298458-p7rvupjo	137	28	those	those	DT
cord-298458-p7rvupjo	137	29	deficiencies	deficiency	NNS
cord-298458-p7rvupjo	137	30	through	through	IN
cord-298458-p7rvupjo	137	31	alternative	alternative	JJ
cord-298458-p7rvupjo	137	32	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	137	33	.	.	.
cord-298458-p7rvupjo	138	1	One	one	CD
cord-298458-p7rvupjo	138	2	such	such	JJ
cord-298458-p7rvupjo	138	3	mechanism	mechanism	NN
cord-298458-p7rvupjo	138	4	is	be	VBZ
cord-298458-p7rvupjo	138	5	likely	likely	JJ
cord-298458-p7rvupjo	138	6	TNF	TNF	NNP
cord-298458-p7rvupjo	138	7	production	production	NN
cord-298458-p7rvupjo	138	8	,	,	,
cord-298458-p7rvupjo	138	9	as	as	IN
cord-298458-p7rvupjo	138	10	neutralization	neutralization	NN
cord-298458-p7rvupjo	138	11	of	of	IN
cord-298458-p7rvupjo	138	12	TNF	TNF	NNP
cord-298458-p7rvupjo	138	13	in	in	IN
cord-298458-p7rvupjo	138	14	perforin	perforin	NNP
cord-298458-p7rvupjo	138	15	-	-	HYPH
cord-298458-p7rvupjo	138	16	deficient	deficient	JJ
cord-298458-p7rvupjo	138	17	and	and	CC
cord-298458-p7rvupjo	138	18	gld	gld	NNP
cord-298458-p7rvupjo	138	19	mice	mouse	NNS
cord-298458-p7rvupjo	138	20	significantly	significantly	RB
cord-298458-p7rvupjo	138	21	increased	increase	VBD
cord-298458-p7rvupjo	138	22	viral	viral	JJ
cord-298458-p7rvupjo	138	23	titers	titer	NNS
cord-298458-p7rvupjo	138	24	compared	compare	VBN
cord-298458-p7rvupjo	138	25	to	to	IN
cord-298458-p7rvupjo	138	26	IgG	igg	NN
cord-298458-p7rvupjo	138	27	-	-	HYPH
cord-298458-p7rvupjo	138	28	treated	treat	VBN
cord-298458-p7rvupjo	138	29	controls	control	NNS
cord-298458-p7rvupjo	138	30	(	(	-LRB-
cord-298458-p7rvupjo	138	31	101	101	CD
cord-298458-p7rvupjo	138	32	)	)	-RRB-
cord-298458-p7rvupjo	138	33	.	.	.
cord-298458-p7rvupjo	139	1	This	this	DT
cord-298458-p7rvupjo	139	2	is	be	VBZ
cord-298458-p7rvupjo	139	3	in	in	IN
cord-298458-p7rvupjo	139	4	contrast	contrast	NN
cord-298458-p7rvupjo	139	5	to	to	IN
cord-298458-p7rvupjo	139	6	studies	study	NNS
cord-298458-p7rvupjo	139	7	following	follow	VBG
cord-298458-p7rvupjo	139	8	PVM	PVM	NNP
cord-298458-p7rvupjo	139	9	and	and	CC
cord-298458-p7rvupjo	139	10	IAV	IAV	NNP
cord-298458-p7rvupjo	139	11	infections	infection	NNS
cord-298458-p7rvupjo	139	12	,	,	,
cord-298458-p7rvupjo	139	13	where	where	WRB
cord-298458-p7rvupjo	139	14	viral	viral	JJ
cord-298458-p7rvupjo	139	15	clearance	clearance	NN
cord-298458-p7rvupjo	139	16	occurs	occur	VBZ
cord-298458-p7rvupjo	139	17	independently	independently	RB
cord-298458-p7rvupjo	139	18	of	of	IN
cord-298458-p7rvupjo	139	19	TNF	TNF	NNP
cord-298458-p7rvupjo	139	20	(	(	-LRB-
cord-298458-p7rvupjo	139	21	102	102	CD
cord-298458-p7rvupjo	139	22	,	,	,
cord-298458-p7rvupjo	139	23	103	103	CD
cord-298458-p7rvupjo	139	24	)	)	-RRB-
cord-298458-p7rvupjo	139	25	.	.	.
cord-298458-p7rvupjo	140	1	IFN	IFN	NNP
cord-298458-p7rvupjo	140	2	-	-	HYPH
cord-298458-p7rvupjo	140	3	γ	γ	NNP
cord-298458-p7rvupjo	140	4	does	do	VBZ
cord-298458-p7rvupjo	140	5	not	not	RB
cord-298458-p7rvupjo	140	6	appear	appear	VB
cord-298458-p7rvupjo	140	7	to	to	TO
cord-298458-p7rvupjo	140	8	play	play	VB
cord-298458-p7rvupjo	140	9	a	a	DT
cord-298458-p7rvupjo	140	10	prominent	prominent	JJ
cord-298458-p7rvupjo	140	11	role	role	NN
cord-298458-p7rvupjo	140	12	in	in	IN
cord-298458-p7rvupjo	140	13	CD8	CD8	NNP
cord-298458-p7rvupjo	140	14	T	T	NNP
cord-298458-p7rvupjo	140	15	cell	cell	NN
cord-298458-p7rvupjo	140	16	-	-	HYPH
cord-298458-p7rvupjo	140	17	mediated	mediate	VBN
cord-298458-p7rvupjo	140	18	viral	viral	JJ
cord-298458-p7rvupjo	140	19	clearance	clearance	NN
cord-298458-p7rvupjo	140	20	,	,	,
cord-298458-p7rvupjo	140	21	as	as	IN
cord-298458-p7rvupjo	140	22	both	both	CC
cord-298458-p7rvupjo	140	23	IFN	IFN	NNP
cord-298458-p7rvupjo	140	24	-	-	HYPH
cord-298458-p7rvupjo	140	25	γ	γ	NN
cord-298458-p7rvupjo	140	26	-	-	HYPH
cord-298458-p7rvupjo	140	27	deficient	deficient	JJ
cord-298458-p7rvupjo	140	28	mice	mouse	NNS
cord-298458-p7rvupjo	140	29	and	and	CC
cord-298458-p7rvupjo	140	30	mice	mouse	NNS
cord-298458-p7rvupjo	140	31	that	that	WDT
cord-298458-p7rvupjo	140	32	received	receive	VBD
cord-298458-p7rvupjo	140	33	IFN	IFN	NNP
cord-298458-p7rvupjo	140	34	-	-	HYPH
cord-298458-p7rvupjo	140	35	γdeficient	γdeficient	NNP
cord-298458-p7rvupjo	140	36	CD8	CD8	NNP
cord-298458-p7rvupjo	140	37	T	T	NNP
cord-298458-p7rvupjo	140	38	cells	cell	NNS
cord-298458-p7rvupjo	140	39	exhibit	exhibit	VBP
cord-298458-p7rvupjo	140	40	equivalent	equivalent	JJ
cord-298458-p7rvupjo	140	41	viral	viral	JJ
cord-298458-p7rvupjo	140	42	titers	titer	NNS
cord-298458-p7rvupjo	140	43	to	to	IN
cord-298458-p7rvupjo	140	44	wild	wild	JJ
cord-298458-p7rvupjo	140	45	-	-	HYPH
cord-298458-p7rvupjo	140	46	type	type	NN
cord-298458-p7rvupjo	140	47	mice	mice	NN
cord-298458-p7rvupjo	140	48	following	follow	VBG
cord-298458-p7rvupjo	140	49	RSV	RSV	NNP
cord-298458-p7rvupjo	140	50	,	,	,
cord-298458-p7rvupjo	140	51	PVM	PVM	NNP
cord-298458-p7rvupjo	140	52	,	,	,
cord-298458-p7rvupjo	140	53	or	or	CC
cord-298458-p7rvupjo	140	54	IAV	IAV	NNP
cord-298458-p7rvupjo	140	55	infections	infection	NNS
cord-298458-p7rvupjo	140	56	(	(	-LRB-
cord-298458-p7rvupjo	140	57	101	101	CD
cord-298458-p7rvupjo	140	58	,	,	,
cord-298458-p7rvupjo	140	59	(	(	-LRB-
cord-298458-p7rvupjo	140	60	103	103	CD
cord-298458-p7rvupjo	140	61	)	)	-RRB-
cord-298458-p7rvupjo	140	62	(	(	-LRB-
cord-298458-p7rvupjo	140	63	104	104	CD
cord-298458-p7rvupjo	140	64	)	)	-RRB-
cord-298458-p7rvupjo	140	65	(	(	-LRB-
cord-298458-p7rvupjo	140	66	105	105	CD
cord-298458-p7rvupjo	140	67	)	)	-RRB-
cord-298458-p7rvupjo	140	68	.	.	.
cord-298458-p7rvupjo	141	1	Together	together	RB
cord-298458-p7rvupjo	141	2	,	,	,
cord-298458-p7rvupjo	141	3	these	these	DT
cord-298458-p7rvupjo	141	4	studies	study	NNS
cord-298458-p7rvupjo	141	5	demonstrate	demonstrate	VBP
cord-298458-p7rvupjo	141	6	that	that	IN
cord-298458-p7rvupjo	141	7	CD8	CD8	NNP
cord-298458-p7rvupjo	141	8	T	T	NNP
cord-298458-p7rvupjo	141	9	cells	cell	NNS
cord-298458-p7rvupjo	141	10	use	use	VBP
cord-298458-p7rvupjo	141	11	multiple	multiple	JJ
cord-298458-p7rvupjo	141	12	complementary	complementary	JJ
cord-298458-p7rvupjo	141	13	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	141	14	to	to	TO
cord-298458-p7rvupjo	141	15	eliminate	eliminate	VB
cord-298458-p7rvupjo	141	16	virally	virally	RB
cord-298458-p7rvupjo	141	17	infected	infect	VBN
cord-298458-p7rvupjo	141	18	cells	cell	NNS
cord-298458-p7rvupjo	141	19	following	follow	VBG
cord-298458-p7rvupjo	141	20	a	a	DT
cord-298458-p7rvupjo	141	21	respiratory	respiratory	JJ
cord-298458-p7rvupjo	141	22	virus	virus	NN
cord-298458-p7rvupjo	141	23	infection	infection	NN
cord-298458-p7rvupjo	141	24	.	.	.
cord-298458-p7rvupjo	142	1	Given	give	VBN
cord-298458-p7rvupjo	142	2	the	the	DT
cord-298458-p7rvupjo	142	3	ability	ability	NN
cord-298458-p7rvupjo	142	4	of	of	IN
cord-298458-p7rvupjo	142	5	CD8	CD8	NNP
cord-298458-p7rvupjo	142	6	T	T	NNP
cord-298458-p7rvupjo	142	7	cells	cell	NNS
cord-298458-p7rvupjo	142	8	to	to	TO
cord-298458-p7rvupjo	142	9	mediate	mediate	VB
cord-298458-p7rvupjo	142	10	viral	viral	JJ
cord-298458-p7rvupjo	142	11	clearance	clearance	NN
cord-298458-p7rvupjo	142	12	following	follow	VBG
cord-298458-p7rvupjo	142	13	an	an	DT
cord-298458-p7rvupjo	142	14	acute	acute	JJ
cord-298458-p7rvupjo	142	15	viral	viral	JJ
cord-298458-p7rvupjo	142	16	infection	infection	NN
cord-298458-p7rvupjo	142	17	,	,	,
cord-298458-p7rvupjo	142	18	it	-PRON-	PRP
cord-298458-p7rvupjo	142	19	is	be	VBZ
cord-298458-p7rvupjo	142	20	no	no	DT
cord-298458-p7rvupjo	142	21	surprise	surprise	NN
cord-298458-p7rvupjo	142	22	that	that	IN
cord-298458-p7rvupjo	142	23	memory	memory	NN
cord-298458-p7rvupjo	142	24	CD8	CD8	NNP
cord-298458-p7rvupjo	142	25	T	T	NNP
cord-298458-p7rvupjo	142	26	cells	cell	NNS
cord-298458-p7rvupjo	142	27	also	also	RB
cord-298458-p7rvupjo	142	28	play	play	VBP
cord-298458-p7rvupjo	142	29	a	a	DT
cord-298458-p7rvupjo	142	30	critical	critical	JJ
cord-298458-p7rvupjo	142	31	role	role	NN
cord-298458-p7rvupjo	142	32	in	in	IN
cord-298458-p7rvupjo	142	33	protecting	protect	VBG
cord-298458-p7rvupjo	142	34	against	against	IN
cord-298458-p7rvupjo	142	35	secondary	secondary	JJ
cord-298458-p7rvupjo	142	36	respiratory	respiratory	JJ
cord-298458-p7rvupjo	142	37	virus	virus	NN
cord-298458-p7rvupjo	142	38	infections	infection	NNS
cord-298458-p7rvupjo	142	39	.	.	.
cord-298458-p7rvupjo	143	1	The	the	DT
cord-298458-p7rvupjo	143	2	adoptive	adoptive	JJ
cord-298458-p7rvupjo	143	3	transfer	transfer	NN
cord-298458-p7rvupjo	143	4	of	of	IN
cord-298458-p7rvupjo	143	5	airway	airway	NN
cord-298458-p7rvupjo	143	6	IAV	iav	NN
cord-298458-p7rvupjo	143	7	-	-	HYPH
cord-298458-p7rvupjo	143	8	specific	specific	JJ
cord-298458-p7rvupjo	143	9	memory	memory	NN
cord-298458-p7rvupjo	143	10	CD8	CD8	NNP
cord-298458-p7rvupjo	143	11	T	T	NNP
cord-298458-p7rvupjo	143	12	cells	cell	NNS
cord-298458-p7rvupjo	143	13	resulted	result	VBD
cord-298458-p7rvupjo	143	14	in	in	IN
cord-298458-p7rvupjo	143	15	significantly	significantly	RB
cord-298458-p7rvupjo	143	16	reduced	reduce	VBN
cord-298458-p7rvupjo	143	17	lung	lung	NN
cord-298458-p7rvupjo	143	18	titers	titer	NNS
cord-298458-p7rvupjo	143	19	following	follow	VBG
cord-298458-p7rvupjo	143	20	IAV	IAV	NNP
cord-298458-p7rvupjo	143	21	challenge	challenge	NN
cord-298458-p7rvupjo	143	22	compared	compare	VBN
cord-298458-p7rvupjo	143	23	to	to	IN
cord-298458-p7rvupjo	143	24	PBS	PBS	NNP
cord-298458-p7rvupjo	143	25	transfer	transfer	NN
cord-298458-p7rvupjo	143	26	controls	control	NNS
cord-298458-p7rvupjo	143	27	(	(	-LRB-
cord-298458-p7rvupjo	143	28	60	60	CD
cord-298458-p7rvupjo	143	29	)	)	-RRB-
cord-298458-p7rvupjo	143	30	.	.	.
cord-298458-p7rvupjo	144	1	Similarly	similarly	RB
cord-298458-p7rvupjo	144	2	,	,	,
cord-298458-p7rvupjo	144	3	transfer	transfer	NN
cord-298458-p7rvupjo	144	4	of	of	IN
cord-298458-p7rvupjo	144	5	airway	airway	NN
cord-298458-p7rvupjo	144	6	RSV	rsv	NN
cord-298458-p7rvupjo	144	7	-	-	HYPH
cord-298458-p7rvupjo	144	8	specific	specific	JJ
cord-298458-p7rvupjo	144	9	memory	memory	NN
cord-298458-p7rvupjo	144	10	CD8	CD8	NNP
cord-298458-p7rvupjo	144	11	T	T	NNP
cord-298458-p7rvupjo	144	12	cells	cell	NNS
cord-298458-p7rvupjo	144	13	reduced	reduce	VBD
cord-298458-p7rvupjo	144	14	lung	lung	NN
cord-298458-p7rvupjo	144	15	viral	viral	JJ
cord-298458-p7rvupjo	144	16	load	load	NN
cord-298458-p7rvupjo	144	17	and	and	CC
cord-298458-p7rvupjo	144	18	weight	weight	NN
cord-298458-p7rvupjo	144	19	loss	loss	NN
cord-298458-p7rvupjo	144	20	following	follow	VBG
cord-298458-p7rvupjo	144	21	subsequent	subsequent	JJ
cord-298458-p7rvupjo	144	22	RSV	RSV	NNP
cord-298458-p7rvupjo	144	23	infection	infection	NN
cord-298458-p7rvupjo	144	24	(	(	-LRB-
cord-298458-p7rvupjo	144	25	76	76	CD
cord-298458-p7rvupjo	144	26	)	)	-RRB-
cord-298458-p7rvupjo	144	27	.	.	.
cord-298458-p7rvupjo	145	1	These	these	DT
cord-298458-p7rvupjo	145	2	studies	study	NNS
cord-298458-p7rvupjo	145	3	indicate	indicate	VBP
cord-298458-p7rvupjo	145	4	that	that	IN
cord-298458-p7rvupjo	145	5	transferred	transfer	VBN
cord-298458-p7rvupjo	145	6	memory	memory	NN
cord-298458-p7rvupjo	145	7	CD8	CD8	NNP
cord-298458-p7rvupjo	145	8	T	T	NNP
cord-298458-p7rvupjo	145	9	cells	cell	NNS
cord-298458-p7rvupjo	145	10	are	be	VBP
cord-298458-p7rvupjo	145	11	capable	capable	JJ
cord-298458-p7rvupjo	145	12	of	of	IN
cord-298458-p7rvupjo	145	13	providing	provide	VBG
cord-298458-p7rvupjo	145	14	protection	protection	NN
cord-298458-p7rvupjo	145	15	against	against	IN
cord-298458-p7rvupjo	145	16	secondary	secondary	JJ
cord-298458-p7rvupjo	145	17	respiratory	respiratory	JJ
cord-298458-p7rvupjo	145	18	virus	virus	NN
cord-298458-p7rvupjo	145	19	challenge	challenge	NN
cord-298458-p7rvupjo	145	20	.	.	.
cord-298458-p7rvupjo	146	1	Memory	memory	NN
cord-298458-p7rvupjo	146	2	CD8	CD8	NNP
cord-298458-p7rvupjo	146	3	T	T	NNP
cord-298458-p7rvupjo	146	4	cell	cell	NN
cord-298458-p7rvupjo	146	5	-	-	HYPH
cord-298458-p7rvupjo	146	6	mediated	mediate	VBN
cord-298458-p7rvupjo	146	7	protection	protection	NN
cord-298458-p7rvupjo	146	8	against	against	IN
cord-298458-p7rvupjo	146	9	secondary	secondary	JJ
cord-298458-p7rvupjo	146	10	infection	infection	NN
cord-298458-p7rvupjo	146	11	has	have	VBZ
cord-298458-p7rvupjo	146	12	been	be	VBN
cord-298458-p7rvupjo	146	13	shown	show	VBN
cord-298458-p7rvupjo	146	14	more	more	RBR
cord-298458-p7rvupjo	146	15	convincingly	convincingly	RB
cord-298458-p7rvupjo	146	16	in	in	IN
cord-298458-p7rvupjo	146	17	mouse	mouse	NN
cord-298458-p7rvupjo	146	18	models	model	NNS
cord-298458-p7rvupjo	146	19	through	through	IN
cord-298458-p7rvupjo	146	20	the	the	DT
cord-298458-p7rvupjo	146	21	use	use	NN
cord-298458-p7rvupjo	146	22	of	of	IN
cord-298458-p7rvupjo	146	23	vaccination	vaccination	NN
cord-298458-p7rvupjo	146	24	strategies	strategy	NNS
cord-298458-p7rvupjo	146	25	to	to	TO
cord-298458-p7rvupjo	146	26	generate	generate	VB
cord-298458-p7rvupjo	146	27	virus	virus	NN
cord-298458-p7rvupjo	146	28	-	-	HYPH
cord-298458-p7rvupjo	146	29	specific	specific	JJ
cord-298458-p7rvupjo	146	30	memory	memory	NN
cord-298458-p7rvupjo	146	31	CD8	CD8	NNP
cord-298458-p7rvupjo	146	32	T	T	NNP
cord-298458-p7rvupjo	146	33	cells	cell	NNS
cord-298458-p7rvupjo	146	34	.	.	.
cord-298458-p7rvupjo	147	1	Recombinant	recombinant	JJ
cord-298458-p7rvupjo	147	2	baculovirus	baculovirus	NN
cord-298458-p7rvupjo	147	3	or	or	CC
cord-298458-p7rvupjo	147	4	murine	murine	JJ
cord-298458-p7rvupjo	147	5	cytomegalovirus	cytomegalovirus	NN
cord-298458-p7rvupjo	147	6	(	(	-LRB-
cord-298458-p7rvupjo	147	7	MCMV	MCMV	NNP
cord-298458-p7rvupjo	147	8	)	)	-RRB-
cord-298458-p7rvupjo	147	9	vectors	vector	NNS
cord-298458-p7rvupjo	147	10	expressing	express	VBG
cord-298458-p7rvupjo	147	11	the	the	DT
cord-298458-p7rvupjo	147	12	RSV	RSV	NNP
cord-298458-p7rvupjo	147	13	M2	M2	NNP
cord-298458-p7rvupjo	147	14	protein	protein	NN
cord-298458-p7rvupjo	148	1	induced	induce	VBN
cord-298458-p7rvupjo	148	2	M2-specific	M2-specific	NNP
cord-298458-p7rvupjo	148	3	CD8	CD8	NNP
cord-298458-p7rvupjo	148	4	T	T	NNP
cord-298458-p7rvupjo	148	5	cells	cell	NNS
cord-298458-p7rvupjo	148	6	that	that	WDT
cord-298458-p7rvupjo	148	7	mediated	mediate	VBD
cord-298458-p7rvupjo	148	8	the	the	DT
cord-298458-p7rvupjo	148	9	reduction	reduction	NN
cord-298458-p7rvupjo	148	10	of	of	IN
cord-298458-p7rvupjo	148	11	lung	lung	NN
cord-298458-p7rvupjo	148	12	viral	viral	JJ
cord-298458-p7rvupjo	148	13	titers	titer	NNS
cord-298458-p7rvupjo	148	14	following	follow	VBG
cord-298458-p7rvupjo	148	15	RSV	RSV	NNP
cord-298458-p7rvupjo	148	16	challenge	challenge	NN
cord-298458-p7rvupjo	148	17	(	(	-LRB-
cord-298458-p7rvupjo	148	18	78	78	CD
cord-298458-p7rvupjo	148	19	,	,	,
cord-298458-p7rvupjo	148	20	106	106	CD
cord-298458-p7rvupjo	148	21	)	)	-RRB-
cord-298458-p7rvupjo	148	22	.	.	.
cord-298458-p7rvupjo	149	1	Whole	whole	JJ
cord-298458-p7rvupjo	149	2	protein	protein	NN
cord-298458-p7rvupjo	149	3	vaccination	vaccination	NN
cord-298458-p7rvupjo	149	4	with	with	IN
cord-298458-p7rvupjo	149	5	HMPV	HMPV	NNP
cord-298458-p7rvupjo	149	6	virus	virus	NN
cord-298458-p7rvupjo	149	7	-	-	HYPH
cord-298458-p7rvupjo	149	8	like	like	JJ
cord-298458-p7rvupjo	149	9	particles	particle	NNS
cord-298458-p7rvupjo	149	10	containing	contain	VBG
cord-298458-p7rvupjo	149	11	F	F	NNP
cord-298458-p7rvupjo	149	12	and	and	CC
cord-298458-p7rvupjo	149	13	M	M	NNP
cord-298458-p7rvupjo	149	14	proteins	protein	NNS
cord-298458-p7rvupjo	149	15	elicited	elicit	VBD
cord-298458-p7rvupjo	149	16	HMPV	hmpv	NN
cord-298458-p7rvupjo	149	17	-	-	HYPH
cord-298458-p7rvupjo	149	18	specific	specific	JJ
cord-298458-p7rvupjo	149	19	CD8	CD8	NNP
cord-298458-p7rvupjo	149	20	T	T	NNP
cord-298458-p7rvupjo	149	21	cells	cell	NNS
cord-298458-p7rvupjo	149	22	that	that	WDT
cord-298458-p7rvupjo	149	23	reduced	reduce	VBD
cord-298458-p7rvupjo	149	24	viral	viral	JJ
cord-298458-p7rvupjo	149	25	titers	titer	NNS
cord-298458-p7rvupjo	149	26	in	in	IN
cord-298458-p7rvupjo	149	27	μMT	μMT	:
cord-298458-p7rvupjo	149	28	mice	mouse	NNS
cord-298458-p7rvupjo	149	29	,	,	,
cord-298458-p7rvupjo	149	30	which	which	WDT
cord-298458-p7rvupjo	149	31	lack	lack	VBP
cord-298458-p7rvupjo	149	32	antibodies	antibody	NNS
cord-298458-p7rvupjo	149	33	(	(	-LRB-
cord-298458-p7rvupjo	149	34	107	107	CD
cord-298458-p7rvupjo	149	35	)	)	-RRB-
cord-298458-p7rvupjo	149	36	.	.	.
cord-298458-p7rvupjo	150	1	CD8	CD8	NNP
cord-298458-p7rvupjo	150	2	T	T	NNP
cord-298458-p7rvupjo	150	3	cell	cell	NN
cord-298458-p7rvupjo	150	4	epitope	epitope	NN
cord-298458-p7rvupjo	150	5	vaccines	vaccine	NNS
cord-298458-p7rvupjo	150	6	against	against	IN
cord-298458-p7rvupjo	150	7	either	either	CC
cord-298458-p7rvupjo	150	8	RSV	RSV	NNP
cord-298458-p7rvupjo	150	9	or	or	CC
cord-298458-p7rvupjo	150	10	HMPV	HMPV	NNP
cord-298458-p7rvupjo	150	11	have	have	VBP
cord-298458-p7rvupjo	150	12	also	also	RB
cord-298458-p7rvupjo	150	13	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	150	14	CD8	CD8	NNP
cord-298458-p7rvupjo	150	15	T	T	NNP
cord-298458-p7rvupjo	150	16	cell	cell	NN
cord-298458-p7rvupjo	150	17	-	-	HYPH
cord-298458-p7rvupjo	150	18	mediated	mediate	VBN
cord-298458-p7rvupjo	150	19	protection	protection	NN
cord-298458-p7rvupjo	150	20	following	follow	VBG
cord-298458-p7rvupjo	150	21	challenge	challenge	NN
cord-298458-p7rvupjo	150	22	by	by	IN
cord-298458-p7rvupjo	150	23	reducing	reduce	VBG
cord-298458-p7rvupjo	150	24	lung	lung	NN
cord-298458-p7rvupjo	150	25	viral	viral	JJ
cord-298458-p7rvupjo	150	26	load	load	NN
cord-298458-p7rvupjo	150	27	and	and	CC
cord-298458-p7rvupjo	150	28	histopathology	histopathology	NN
cord-298458-p7rvupjo	150	29	compared	compare	VBN
cord-298458-p7rvupjo	150	30	to	to	IN
cord-298458-p7rvupjo	150	31	unimmunized	unimmunized	JJ
cord-298458-p7rvupjo	150	32	controls	control	NNS
cord-298458-p7rvupjo	150	33	(	(	-LRB-
cord-298458-p7rvupjo	150	34	108	108	CD
cord-298458-p7rvupjo	150	35	,	,	,
cord-298458-p7rvupjo	150	36	109	109	CD
cord-298458-p7rvupjo	150	37	)	)	-RRB-
cord-298458-p7rvupjo	150	38	.	.	.
cord-298458-p7rvupjo	151	1	A	a	DT
cord-298458-p7rvupjo	151	2	similar	similar	JJ
cord-298458-p7rvupjo	151	3	strategy	strategy	NN
cord-298458-p7rvupjo	151	4	utilizing	utilize	VBG
cord-298458-p7rvupjo	151	5	DC	DC	NNP
cord-298458-p7rvupjo	151	6	-	-	HYPH
cord-298458-p7rvupjo	151	7	peptide	peptide	NN
cord-298458-p7rvupjo	151	8	vaccination	vaccination	NN
cord-298458-p7rvupjo	151	9	to	to	TO
cord-298458-p7rvupjo	151	10	generate	generate	VB
cord-298458-p7rvupjo	151	11	pre	pre	JJ
cord-298458-p7rvupjo	151	12	-	-	JJ
cord-298458-p7rvupjo	151	13	existing	existing	JJ
cord-298458-p7rvupjo	151	14	PVM	pvm	NN
cord-298458-p7rvupjo	151	15	-	-	HYPH
cord-298458-p7rvupjo	151	16	specific	specific	JJ
cord-298458-p7rvupjo	151	17	memory	memory	NN
cord-298458-p7rvupjo	151	18	CD8	CD8	NNP
cord-298458-p7rvupjo	151	19	T	T	NNP
cord-298458-p7rvupjo	151	20	cells	cell	NNS
cord-298458-p7rvupjo	151	21	also	also	RB
cord-298458-p7rvupjo	151	22	resulted	result	VBD
cord-298458-p7rvupjo	151	23	in	in	IN
cord-298458-p7rvupjo	151	24	enhanced	enhance	VBN
cord-298458-p7rvupjo	151	25	viral	viral	JJ
cord-298458-p7rvupjo	151	26	control	control	NN
cord-298458-p7rvupjo	151	27	following	follow	VBG
cord-298458-p7rvupjo	151	28	PVM	PVM	NNP
cord-298458-p7rvupjo	151	29	infection	infection	NN
cord-298458-p7rvupjo	151	30	(	(	-LRB-
cord-298458-p7rvupjo	151	31	42	42	CD
cord-298458-p7rvupjo	151	32	)	)	-RRB-
cord-298458-p7rvupjo	151	33	.	.	.
cord-298458-p7rvupjo	152	1	Recently	recently	RB
cord-298458-p7rvupjo	152	2	,	,	,
cord-298458-p7rvupjo	152	3	several	several	JJ
cord-298458-p7rvupjo	152	4	studies	study	NNS
cord-298458-p7rvupjo	152	5	have	have	VBP
cord-298458-p7rvupjo	152	6	utilized	utilize	VBN
cord-298458-p7rvupjo	152	7	DC	DC	NNP
cord-298458-p7rvupjo	152	8	-	-	HYPH
cord-298458-p7rvupjo	152	9	prime	prime	JJ
cord-298458-p7rvupjo	152	10	,	,	,
cord-298458-p7rvupjo	152	11	recombinant	recombinant	JJ
cord-298458-p7rvupjo	152	12	Listeria	Listeria	NNP
cord-298458-p7rvupjo	152	13	monocytogenes-(DC	monocytogenes-(DC	NNP
cord-298458-p7rvupjo	152	14	-	-	HYPH
cord-298458-p7rvupjo	152	15	LM	LM	NNP
cord-298458-p7rvupjo	152	16	)	)	-RRB-
cord-298458-p7rvupjo	152	17	or	or	CC
cord-298458-p7rvupjo	152	18	vaccinia	vaccinia	NN
cord-298458-p7rvupjo	152	19	virus	virus	NN
cord-298458-p7rvupjo	152	20	-	-	HYPH
cord-298458-p7rvupjo	152	21	boost	boost	NN
cord-298458-p7rvupjo	152	22	(	(	-LRB-
cord-298458-p7rvupjo	152	23	DC	DC	NNP
cord-298458-p7rvupjo	152	24	-	-	HYPH
cord-298458-p7rvupjo	152	25	VV	VV	NNP
cord-298458-p7rvupjo	152	26	)	)	-RRB-
cord-298458-p7rvupjo	152	27	vaccination	vaccination	NN
cord-298458-p7rvupjo	152	28	protocols	protocol	NNS
cord-298458-p7rvupjo	152	29	to	to	TO
cord-298458-p7rvupjo	152	30	generate	generate	VB
cord-298458-p7rvupjo	152	31	a	a	DT
cord-298458-p7rvupjo	152	32	high	high	JJ
cord-298458-p7rvupjo	152	33	frequency	frequency	NN
cord-298458-p7rvupjo	152	34	of	of	IN
cord-298458-p7rvupjo	152	35	pre	pre	JJ
cord-298458-p7rvupjo	152	36	-	-	JJ
cord-298458-p7rvupjo	152	37	existing	existing	JJ
cord-298458-p7rvupjo	152	38	antigen	antigen	NN
cord-298458-p7rvupjo	152	39	-	-	HYPH
cord-298458-p7rvupjo	152	40	specific	specific	JJ
cord-298458-p7rvupjo	152	41	memory	memory	NN
cord-298458-p7rvupjo	152	42	CD8	CD8	NNP
cord-298458-p7rvupjo	152	43	T	T	NNP
cord-298458-p7rvupjo	152	44	cells	cell	NNS
cord-298458-p7rvupjo	152	45	in	in	IN
cord-298458-p7rvupjo	152	46	the	the	DT
cord-298458-p7rvupjo	152	47	absence	absence	NN
cord-298458-p7rvupjo	152	48	of	of	IN
cord-298458-p7rvupjo	152	49	virus	virus	NN
cord-298458-p7rvupjo	152	50	-	-	HYPH
cord-298458-p7rvupjo	152	51	specific	specific	JJ
cord-298458-p7rvupjo	152	52	CD4	CD4	NNP
cord-298458-p7rvupjo	152	53	T	T	NNP
cord-298458-p7rvupjo	152	54	cell	cell	NN
cord-298458-p7rvupjo	152	55	memory	memory	NN
cord-298458-p7rvupjo	152	56	and	and	CC
cord-298458-p7rvupjo	152	57	antibodies	antibody	NNS
cord-298458-p7rvupjo	152	58	(	(	-LRB-
cord-298458-p7rvupjo	152	59	28	28	CD
cord-298458-p7rvupjo	152	60	)	)	-RRB-
cord-298458-p7rvupjo	152	61	(	(	-LRB-
cord-298458-p7rvupjo	152	62	29	29	CD
cord-298458-p7rvupjo	152	63	)	)	-RRB-
cord-298458-p7rvupjo	152	64	(	(	-LRB-
cord-298458-p7rvupjo	152	65	30	30	CD
cord-298458-p7rvupjo	152	66	)	)	-RRB-
cord-298458-p7rvupjo	152	67	.	.	.
cord-298458-p7rvupjo	153	1	Prime	Prime	NNP
cord-298458-p7rvupjo	153	2	-	-	HYPH
cord-298458-p7rvupjo	153	3	boosted	boost	VBN
cord-298458-p7rvupjo	153	4	mice	mouse	NNS
cord-298458-p7rvupjo	153	5	exhibited	exhibit	VBD
cord-298458-p7rvupjo	153	6	significantly	significantly	RB
cord-298458-p7rvupjo	153	7	reduced	reduce	VBN
cord-298458-p7rvupjo	153	8	lung	lung	NN
cord-298458-p7rvupjo	153	9	viral	viral	JJ
cord-298458-p7rvupjo	153	10	titers	titer	NNS
cord-298458-p7rvupjo	153	11	following	follow	VBG
cord-298458-p7rvupjo	153	12	RSV	RSV	NNP
cord-298458-p7rvupjo	153	13	,	,	,
cord-298458-p7rvupjo	153	14	IAV	IAV	NNP
cord-298458-p7rvupjo	153	15	,	,	,
cord-298458-p7rvupjo	153	16	or	or	CC
cord-298458-p7rvupjo	153	17	SARS	SARS	NNP
cord-298458-p7rvupjo	153	18	infections	infection	NNS
cord-298458-p7rvupjo	153	19	compared	compare	VBN
cord-298458-p7rvupjo	153	20	to	to	IN
cord-298458-p7rvupjo	153	21	controls	control	NNS
cord-298458-p7rvupjo	153	22	lacking	lack	VBG
cord-298458-p7rvupjo	153	23	virus	virus	NN
cord-298458-p7rvupjo	153	24	-	-	HYPH
cord-298458-p7rvupjo	153	25	specific	specific	JJ
cord-298458-p7rvupjo	153	26	memory	memory	NN
cord-298458-p7rvupjo	153	27	CD8	CD8	NNP
cord-298458-p7rvupjo	153	28	T	T	NNP
cord-298458-p7rvupjo	153	29	cells	cell	NNS
cord-298458-p7rvupjo	153	30	.	.	.
cord-298458-p7rvupjo	154	1	Additionally	additionally	RB
cord-298458-p7rvupjo	154	2	,	,	,
cord-298458-p7rvupjo	154	3	memory	memory	NN
cord-298458-p7rvupjo	154	4	CD8	CD8	NNP
cord-298458-p7rvupjo	154	5	T	T	NNP
cord-298458-p7rvupjo	154	6	cells	cell	NNS
cord-298458-p7rvupjo	154	7	were	be	VBD
cord-298458-p7rvupjo	154	8	able	able	JJ
cord-298458-p7rvupjo	154	9	to	to	TO
cord-298458-p7rvupjo	154	10	reduce	reduce	VB
cord-298458-p7rvupjo	154	11	weight	weight	NN
cord-298458-p7rvupjo	154	12	loss	loss	NN
cord-298458-p7rvupjo	154	13	and	and	CC
cord-298458-p7rvupjo	154	14	mortality	mortality	NN
cord-298458-p7rvupjo	154	15	following	follow	VBG
cord-298458-p7rvupjo	154	16	lethal	lethal	JJ
cord-298458-p7rvupjo	154	17	challenges	challenge	NNS
cord-298458-p7rvupjo	154	18	with	with	IN
cord-298458-p7rvupjo	154	19	either	either	CC
cord-298458-p7rvupjo	154	20	IAV	IAV	NNP
cord-298458-p7rvupjo	154	21	or	or	CC
cord-298458-p7rvupjo	154	22	SARS	SARS	NNP
cord-298458-p7rvupjo	154	23	.	.	.
cord-298458-p7rvupjo	155	1	Overall	overall	RB
cord-298458-p7rvupjo	155	2	,	,	,
cord-298458-p7rvupjo	155	3	these	these	DT
cord-298458-p7rvupjo	155	4	studies	study	NNS
cord-298458-p7rvupjo	155	5	provide	provide	VBP
cord-298458-p7rvupjo	155	6	clear	clear	JJ
cord-298458-p7rvupjo	155	7	evidence	evidence	NN
cord-298458-p7rvupjo	155	8	that	that	IN
cord-298458-p7rvupjo	155	9	memory	memory	NN
cord-298458-p7rvupjo	155	10	CD8	CD8	NNP
cord-298458-p7rvupjo	155	11	T	T	NNP
cord-298458-p7rvupjo	155	12	cells	cell	NNS
cord-298458-p7rvupjo	155	13	provide	provide	VBP
cord-298458-p7rvupjo	155	14	protection	protection	NN
cord-298458-p7rvupjo	155	15	against	against	IN
cord-298458-p7rvupjo	155	16	secondary	secondary	JJ
cord-298458-p7rvupjo	155	17	respiratory	respiratory	JJ
cord-298458-p7rvupjo	155	18	virus	virus	NN
cord-298458-p7rvupjo	155	19	infection	infection	NN
cord-298458-p7rvupjo	155	20	by	by	IN
cord-298458-p7rvupjo	155	21	reducing	reduce	VBG
cord-298458-p7rvupjo	155	22	viral	viral	JJ
cord-298458-p7rvupjo	155	23	titers	titer	NNS
cord-298458-p7rvupjo	155	24	.	.	.
cord-298458-p7rvupjo	156	1	The	the	DT
cord-298458-p7rvupjo	156	2	most	most	RBS
cord-298458-p7rvupjo	156	3	well	well	RB
cord-298458-p7rvupjo	156	4	studied	study	VBN
cord-298458-p7rvupjo	156	5	example	example	NN
cord-298458-p7rvupjo	156	6	of	of	IN
cord-298458-p7rvupjo	156	7	memory	memory	NN
cord-298458-p7rvupjo	156	8	CD8	CD8	NNP
cord-298458-p7rvupjo	156	9	T	T	NNP
cord-298458-p7rvupjo	156	10	cellmediated	cellmediate	VBN
cord-298458-p7rvupjo	156	11	protection	protection	NN
cord-298458-p7rvupjo	156	12	from	from	IN
cord-298458-p7rvupjo	156	13	a	a	DT
cord-298458-p7rvupjo	156	14	secondary	secondary	JJ
cord-298458-p7rvupjo	156	15	respiratory	respiratory	JJ
cord-298458-p7rvupjo	156	16	virus	virus	NN
cord-298458-p7rvupjo	156	17	infection	infection	NN
cord-298458-p7rvupjo	157	1	is	be	VBZ
cord-298458-p7rvupjo	157	2	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	157	3	immunity	immunity	NN
cord-298458-p7rvupjo	157	4	to	to	IN
cord-298458-p7rvupjo	157	5	IAV	IAV	NNP
cord-298458-p7rvupjo	157	6	subtypes	subtype	NNS
cord-298458-p7rvupjo	157	7	.	.	.
cord-298458-p7rvupjo	158	1	IAV	iav	NN
cord-298458-p7rvupjo	158	2	-	-	HYPH
cord-298458-p7rvupjo	158	3	specific	specific	JJ
cord-298458-p7rvupjo	158	4	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	158	5	antibody	antibody	NN
cord-298458-p7rvupjo	158	6	responses	response	NNS
cord-298458-p7rvupjo	158	7	recognize	recognize	VBP
cord-298458-p7rvupjo	158	8	the	the	DT
cord-298458-p7rvupjo	158	9	surface	surface	NN
cord-298458-p7rvupjo	158	10	glycoproteins	glycoprotein	NNS
cord-298458-p7rvupjo	158	11	hemagglutinin	hemagglutinin	NN
cord-298458-p7rvupjo	158	12	(	(	-LRB-
cord-298458-p7rvupjo	158	13	HA	HA	NNP
cord-298458-p7rvupjo	158	14	)	)	-RRB-
cord-298458-p7rvupjo	158	15	and	and	CC
cord-298458-p7rvupjo	158	16	neuraminidase	neuraminidase	NN
cord-298458-p7rvupjo	158	17	(	(	-LRB-
cord-298458-p7rvupjo	158	18	NA	NA	NNP
cord-298458-p7rvupjo	158	19	)	)	-RRB-
cord-298458-p7rvupjo	158	20	,	,	,
cord-298458-p7rvupjo	158	21	which	which	WDT
cord-298458-p7rvupjo	158	22	vary	vary	VBP
cord-298458-p7rvupjo	158	23	between	between	IN
cord-298458-p7rvupjo	158	24	subtypes	subtype	NNS
cord-298458-p7rvupjo	158	25	as	as	IN
cord-298458-p7rvupjo	158	26	a	a	DT
cord-298458-p7rvupjo	158	27	result	result	NN
cord-298458-p7rvupjo	158	28	of	of	IN
cord-298458-p7rvupjo	158	29	genetic	genetic	JJ
cord-298458-p7rvupjo	158	30	reassortment	reassortment	NN
cord-298458-p7rvupjo	158	31	,	,	,
cord-298458-p7rvupjo	158	32	known	know	VBN
cord-298458-p7rvupjo	158	33	as	as	IN
cord-298458-p7rvupjo	158	34	antigenic	antigenic	JJ
cord-298458-p7rvupjo	158	35	drift	drift	NN
cord-298458-p7rvupjo	158	36	.	.	.
cord-298458-p7rvupjo	159	1	However	however	RB
cord-298458-p7rvupjo	159	2	,	,	,
cord-298458-p7rvupjo	159	3	the	the	DT
cord-298458-p7rvupjo	159	4	internal	internal	JJ
cord-298458-p7rvupjo	159	5	proteins	protein	NNS
cord-298458-p7rvupjo	159	6	of	of	IN
cord-298458-p7rvupjo	159	7	the	the	DT
cord-298458-p7rvupjo	159	8	virus	virus	NN
cord-298458-p7rvupjo	159	9	are	be	VBP
cord-298458-p7rvupjo	159	10	often	often	RB
cord-298458-p7rvupjo	159	11	conserved	conserve	VBN
cord-298458-p7rvupjo	159	12	between	between	IN
cord-298458-p7rvupjo	159	13	IAV	IAV	NNP
cord-298458-p7rvupjo	159	14	subtypes	subtype	NNS
cord-298458-p7rvupjo	159	15	.	.	.
cord-298458-p7rvupjo	160	1	Therefore	therefore	RB
cord-298458-p7rvupjo	160	2	,	,	,
cord-298458-p7rvupjo	160	3	memory	memory	NN
cord-298458-p7rvupjo	160	4	CD8	CD8	NNP
cord-298458-p7rvupjo	160	5	T	T	NNP
cord-298458-p7rvupjo	160	6	cells	cell	NNS
cord-298458-p7rvupjo	160	7	that	that	WDT
cord-298458-p7rvupjo	160	8	recognize	recognize	VBP
cord-298458-p7rvupjo	160	9	epitopes	epitope	NNS
cord-298458-p7rvupjo	160	10	within	within	IN
cord-298458-p7rvupjo	160	11	conserved	conserve	VBN
cord-298458-p7rvupjo	160	12	viral	viral	JJ
cord-298458-p7rvupjo	160	13	proteins	protein	NNS
cord-298458-p7rvupjo	160	14	may	may	MD
cord-298458-p7rvupjo	160	15	be	be	VB
cord-298458-p7rvupjo	160	16	capable	capable	JJ
cord-298458-p7rvupjo	160	17	of	of	IN
cord-298458-p7rvupjo	160	18	providing	provide	VBG
cord-298458-p7rvupjo	160	19	cross	cross	NN
cord-298458-p7rvupjo	160	20	-	-	NN
cord-298458-p7rvupjo	160	21	protection	protection	NN
cord-298458-p7rvupjo	160	22	between	between	IN
cord-298458-p7rvupjo	160	23	IAV	IAV	NNP
cord-298458-p7rvupjo	160	24	viruses	virus	NNS
cord-298458-p7rvupjo	160	25	of	of	IN
cord-298458-p7rvupjo	160	26	differing	differ	VBG
cord-298458-p7rvupjo	160	27	subtypes	subtype	NNS
cord-298458-p7rvupjo	160	28	.	.	.
cord-298458-p7rvupjo	161	1	Evidence	evidence	NN
cord-298458-p7rvupjo	161	2	of	of	IN
cord-298458-p7rvupjo	161	3	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	161	4	immunity	immunity	NN
cord-298458-p7rvupjo	161	5	was	be	VBD
cord-298458-p7rvupjo	161	6	first	first	RB
cord-298458-p7rvupjo	161	7	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	161	8	by	by	IN
cord-298458-p7rvupjo	161	9	the	the	DT
cord-298458-p7rvupjo	161	10	protection	protection	NN
cord-298458-p7rvupjo	161	11	of	of	IN
cord-298458-p7rvupjo	161	12	H1N1	H1N1	NNP
cord-298458-p7rvupjo	161	13	IAV	IAV	NNP
cord-298458-p7rvupjo	161	14	-	-	HYPH
cord-298458-p7rvupjo	161	15	immune	immune	JJ
cord-298458-p7rvupjo	161	16	mice	mouse	NNS
cord-298458-p7rvupjo	161	17	from	from	IN
cord-298458-p7rvupjo	161	18	a	a	DT
cord-298458-p7rvupjo	161	19	lethal	lethal	JJ
cord-298458-p7rvupjo	161	20	H2N2	H2N2	NNP
cord-298458-p7rvupjo	161	21	IAV	IAV	NNP
cord-298458-p7rvupjo	161	22	challenge	challenge	NN
cord-298458-p7rvupjo	161	23	without	without	IN
cord-298458-p7rvupjo	161	24	the	the	DT
cord-298458-p7rvupjo	161	25	induction	induction	NN
cord-298458-p7rvupjo	161	26	of	of	IN
cord-298458-p7rvupjo	161	27	a	a	DT
cord-298458-p7rvupjo	161	28	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	161	29	antibody	antibody	NN
cord-298458-p7rvupjo	161	30	response	response	NN
cord-298458-p7rvupjo	161	31	(	(	-LRB-
cord-298458-p7rvupjo	161	32	110	110	CD
cord-298458-p7rvupjo	161	33	)	)	-RRB-
cord-298458-p7rvupjo	161	34	.	.	.
cord-298458-p7rvupjo	162	1	Since	since	IN
cord-298458-p7rvupjo	162	2	then	then	RB
cord-298458-p7rvupjo	162	3	,	,	,
cord-298458-p7rvupjo	162	4	a	a	DT
cord-298458-p7rvupjo	162	5	memory	memory	NN
cord-298458-p7rvupjo	162	6	CD8	CD8	NNP
cord-298458-p7rvupjo	162	7	T	T	NNP
cord-298458-p7rvupjo	162	8	cell	cell	NN
cord-298458-p7rvupjo	162	9	-	-	HYPH
cord-298458-p7rvupjo	162	10	mediated	mediate	VBN
cord-298458-p7rvupjo	162	11	role	role	NN
cord-298458-p7rvupjo	162	12	in	in	IN
cord-298458-p7rvupjo	162	13	accelerating	accelerate	VBG
cord-298458-p7rvupjo	162	14	clearance	clearance	NN
cord-298458-p7rvupjo	162	15	of	of	IN
cord-298458-p7rvupjo	162	16	a	a	DT
cord-298458-p7rvupjo	162	17	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	162	18	IAV	IAV	NNP
cord-298458-p7rvupjo	162	19	strain	strain	NN
cord-298458-p7rvupjo	162	20	has	have	VBZ
cord-298458-p7rvupjo	162	21	been	be	VBN
cord-298458-p7rvupjo	162	22	well	well	RB
cord-298458-p7rvupjo	162	23	-	-	HYPH
cord-298458-p7rvupjo	162	24	established	establish	VBN
cord-298458-p7rvupjo	162	25	in	in	IN
cord-298458-p7rvupjo	162	26	mouse	mouse	NN
cord-298458-p7rvupjo	162	27	,	,	,
cord-298458-p7rvupjo	162	28	chicken	chicken	NN
cord-298458-p7rvupjo	162	29	and	and	CC
cord-298458-p7rvupjo	162	30	non	non	JJ
cord-298458-p7rvupjo	162	31	-	-	JJ
cord-298458-p7rvupjo	162	32	human	human	JJ
cord-298458-p7rvupjo	162	33	primate	primate	NN
cord-298458-p7rvupjo	162	34	models	model	NNS
cord-298458-p7rvupjo	162	35	(	(	-LRB-
cord-298458-p7rvupjo	162	36	66	66	CD
cord-298458-p7rvupjo	162	37	,	,	,
cord-298458-p7rvupjo	162	38	(	(	-LRB-
cord-298458-p7rvupjo	162	39	111	111	CD
cord-298458-p7rvupjo	162	40	)	)	-RRB-
cord-298458-p7rvupjo	162	41	(	(	-LRB-
cord-298458-p7rvupjo	162	42	112	112	CD
cord-298458-p7rvupjo	162	43	)	)	-RRB-
cord-298458-p7rvupjo	162	44	(	(	-LRB-
cord-298458-p7rvupjo	162	45	113	113	CD
cord-298458-p7rvupjo	162	46	)	)	-RRB-
cord-298458-p7rvupjo	162	47	(	(	-LRB-
cord-298458-p7rvupjo	162	48	114	114	CD
cord-298458-p7rvupjo	162	49	)	)	-RRB-
cord-298458-p7rvupjo	162	50	.	.	.
cord-298458-p7rvupjo	163	1	Recently	recently	RB
cord-298458-p7rvupjo	163	2	,	,	,
cord-298458-p7rvupjo	163	3	it	-PRON-	PRP
cord-298458-p7rvupjo	163	4	has	have	VBZ
cord-298458-p7rvupjo	163	5	been	be	VBN
cord-298458-p7rvupjo	163	6	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	163	7	that	that	IN
cord-298458-p7rvupjo	163	8	TRM	TRM	NNP
cord-298458-p7rvupjo	163	9	are	be	VBP
cord-298458-p7rvupjo	163	10	essential	essential	JJ
cord-298458-p7rvupjo	163	11	in	in	IN
cord-298458-p7rvupjo	163	12	providing	provide	VBG
cord-298458-p7rvupjo	163	13	cross	cross	NN
cord-298458-p7rvupjo	163	14	-	-	NN
cord-298458-p7rvupjo	163	15	protection	protection	NN
cord-298458-p7rvupjo	163	16	against	against	IN
cord-298458-p7rvupjo	163	17	secondary	secondary	JJ
cord-298458-p7rvupjo	163	18	IAV	IAV	NNP
cord-298458-p7rvupjo	163	19	infection	infection	NN
cord-298458-p7rvupjo	163	20	with	with	IN
cord-298458-p7rvupjo	163	21	a	a	DT
cord-298458-p7rvupjo	163	22	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	163	23	strain	strain	NN
cord-298458-p7rvupjo	163	24	(	(	-LRB-
cord-298458-p7rvupjo	163	25	60	60	CD
cord-298458-p7rvupjo	163	26	,	,	,
cord-298458-p7rvupjo	163	27	66	66	CD
cord-298458-p7rvupjo	163	28	,	,	,
cord-298458-p7rvupjo	163	29	80	80	CD
cord-298458-p7rvupjo	163	30	)	)	-RRB-
cord-298458-p7rvupjo	163	31	.	.	.
cord-298458-p7rvupjo	164	1	Mice	mouse	NNS
cord-298458-p7rvupjo	164	2	with	with	IN
cord-298458-p7rvupjo	164	3	CD103	CD103	NNP
cord-298458-p7rvupjo	164	4	+	+	CC
cord-298458-p7rvupjo	164	5	TRM	trm	NN
cord-298458-p7rvupjo	164	6	in	in	IN
cord-298458-p7rvupjo	164	7	the	the	DT
cord-298458-p7rvupjo	164	8	lung	lung	NN
cord-298458-p7rvupjo	164	9	exhibit	exhibit	NN
cord-298458-p7rvupjo	164	10	more	more	RBR
cord-298458-p7rvupjo	164	11	efficient	efficient	JJ
cord-298458-p7rvupjo	164	12	viral	viral	JJ
cord-298458-p7rvupjo	164	13	clearance	clearance	NN
cord-298458-p7rvupjo	164	14	and	and	CC
cord-298458-p7rvupjo	164	15	reduced	reduced	JJ
cord-298458-p7rvupjo	164	16	weight	weight	NN
cord-298458-p7rvupjo	164	17	loss	loss	NN
cord-298458-p7rvupjo	164	18	following	follow	VBG
cord-298458-p7rvupjo	164	19	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	164	20	challenge	challenge	NN
cord-298458-p7rvupjo	164	21	than	than	IN
cord-298458-p7rvupjo	164	22	mice	mouse	NNS
cord-298458-p7rvupjo	164	23	lacking	lack	VBG
cord-298458-p7rvupjo	164	24	a	a	DT
cord-298458-p7rvupjo	164	25	TRM	TRM	NNP
cord-298458-p7rvupjo	164	26	response	response	NN
cord-298458-p7rvupjo	164	27	(	(	-LRB-
cord-298458-p7rvupjo	164	28	66	66	CD
cord-298458-p7rvupjo	164	29	)	)	-RRB-
cord-298458-p7rvupjo	164	30	.	.	.
cord-298458-p7rvupjo	165	1	Importantly	importantly	RB
cord-298458-p7rvupjo	165	2	,	,	,
cord-298458-p7rvupjo	165	3	the	the	DT
cord-298458-p7rvupjo	165	4	protection	protection	NN
cord-298458-p7rvupjo	165	5	was	be	VBD
cord-298458-p7rvupjo	165	6	provided	provide	VBN
cord-298458-p7rvupjo	165	7	solely	solely	RB
cord-298458-p7rvupjo	165	8	by	by	IN
cord-298458-p7rvupjo	165	9	lung	lung	NN
cord-298458-p7rvupjo	165	10	-	-	HYPH
cord-298458-p7rvupjo	165	11	resident	resident	NN
cord-298458-p7rvupjo	165	12	memory	memory	NN
cord-298458-p7rvupjo	165	13	CD8	CD8	NNP
cord-298458-p7rvupjo	165	14	T	T	NNP
cord-298458-p7rvupjo	165	15	cells	cell	NNS
cord-298458-p7rvupjo	165	16	,	,	,
cord-298458-p7rvupjo	165	17	as	as	IN
cord-298458-p7rvupjo	165	18	blocking	block	VBG
cord-298458-p7rvupjo	165	19	the	the	DT
cord-298458-p7rvupjo	165	20	ability	ability	NN
cord-298458-p7rvupjo	165	21	of	of	IN
cord-298458-p7rvupjo	165	22	recently	recently	RB
cord-298458-p7rvupjo	165	23	proliferated	proliferate	VBN
cord-298458-p7rvupjo	165	24	TCM	TCM	NNP
cord-298458-p7rvupjo	165	25	cells	cell	NNS
cord-298458-p7rvupjo	165	26	from	from	IN
cord-298458-p7rvupjo	165	27	trafficking	traffic	VBG
cord-298458-p7rvupjo	165	28	to	to	IN
cord-298458-p7rvupjo	165	29	the	the	DT
cord-298458-p7rvupjo	165	30	lung	lung	NN
cord-298458-p7rvupjo	165	31	did	do	VBD
cord-298458-p7rvupjo	165	32	not	not	RB
cord-298458-p7rvupjo	165	33	impact	impact	VB
cord-298458-p7rvupjo	165	34	protection	protection	NN
cord-298458-p7rvupjo	165	35	(	(	-LRB-
cord-298458-p7rvupjo	165	36	66	66	CD
cord-298458-p7rvupjo	165	37	)	)	-RRB-
cord-298458-p7rvupjo	165	38	.	.	.
cord-298458-p7rvupjo	166	1	Consistent	consistent	JJ
cord-298458-p7rvupjo	166	2	with	with	IN
cord-298458-p7rvupjo	166	3	the	the	DT
cord-298458-p7rvupjo	166	4	limited	limited	JJ
cord-298458-p7rvupjo	166	5	lifespan	lifespan	NN
cord-298458-p7rvupjo	166	6	of	of	IN
cord-298458-p7rvupjo	166	7	IAV	iav	NN
cord-298458-p7rvupjo	166	8	-	-	HYPH
cord-298458-p7rvupjo	166	9	specific	specific	JJ
cord-298458-p7rvupjo	166	10	TRM	TRM	NNP
cord-298458-p7rvupjo	166	11	,	,	,
cord-298458-p7rvupjo	166	12	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	166	13	protection	protection	NN
cord-298458-p7rvupjo	166	14	by	by	IN
cord-298458-p7rvupjo	166	15	memory	memory	NN
cord-298458-p7rvupjo	166	16	CD8	CD8	NNP
cord-298458-p7rvupjo	166	17	T	T	NNP
cord-298458-p7rvupjo	166	18	cells	cell	NNS
cord-298458-p7rvupjo	166	19	wanes	wane	VBZ
cord-298458-p7rvupjo	166	20	over	over	IN
cord-298458-p7rvupjo	166	21	time	time	NN
cord-298458-p7rvupjo	166	22	,	,	,
cord-298458-p7rvupjo	166	23	with	with	IN
cord-298458-p7rvupjo	166	24	a	a	DT
cord-298458-p7rvupjo	166	25	decline	decline	NN
cord-298458-p7rvupjo	166	26	observed	observe	VBN
cord-298458-p7rvupjo	166	27	as	as	RB
cord-298458-p7rvupjo	166	28	early	early	RB
cord-298458-p7rvupjo	166	29	as	as	IN
cord-298458-p7rvupjo	166	30	60	60	CD
cord-298458-p7rvupjo	166	31	days	day	NNS
cord-298458-p7rvupjo	166	32	following	follow	VBG
cord-298458-p7rvupjo	166	33	the	the	DT
cord-298458-p7rvupjo	166	34	initial	initial	JJ
cord-298458-p7rvupjo	166	35	infection	infection	NN
cord-298458-p7rvupjo	166	36	(	(	-LRB-
cord-298458-p7rvupjo	166	37	80	80	CD
cord-298458-p7rvupjo	166	38	,	,	,
cord-298458-p7rvupjo	166	39	111	111	CD
cord-298458-p7rvupjo	166	40	)	)	-RRB-
cord-298458-p7rvupjo	166	41	.	.	.
cord-298458-p7rvupjo	167	1	Interestingly	interestingly	RB
cord-298458-p7rvupjo	167	2	,	,	,
cord-298458-p7rvupjo	167	3	systemic	systemic	JJ
cord-298458-p7rvupjo	167	4	immunization	immunization	NN
cord-298458-p7rvupjo	167	5	with	with	IN
cord-298458-p7rvupjo	167	6	cognate	cognate	JJ
cord-298458-p7rvupjo	167	7	antigen	antigen	NN
cord-298458-p7rvupjo	167	8	is	be	VBZ
cord-298458-p7rvupjo	167	9	capable	capable	JJ
cord-298458-p7rvupjo	167	10	of	of	IN
cord-298458-p7rvupjo	167	11	boosting	boost	VBG
cord-298458-p7rvupjo	167	12	the	the	DT
cord-298458-p7rvupjo	167	13	TRM	TRM	NNP
cord-298458-p7rvupjo	167	14	pool	pool	NN
cord-298458-p7rvupjo	167	15	by	by	IN
cord-298458-p7rvupjo	167	16	expanding	expand	VBG
cord-298458-p7rvupjo	167	17	the	the	DT
cord-298458-p7rvupjo	167	18	circulating	circulate	VBG
cord-298458-p7rvupjo	167	19	TEM	tem	NN
cord-298458-p7rvupjo	167	20	population	population	NN
cord-298458-p7rvupjo	167	21	that	that	WDT
cord-298458-p7rvupjo	167	22	seeds	seed	VBZ
cord-298458-p7rvupjo	167	23	the	the	DT
cord-298458-p7rvupjo	167	24	lungs	lung	NNS
cord-298458-p7rvupjo	167	25	(	(	-LRB-
cord-298458-p7rvupjo	167	26	80	80	CD
cord-298458-p7rvupjo	167	27	)	)	-RRB-
cord-298458-p7rvupjo	167	28	.	.	.
cord-298458-p7rvupjo	168	1	Therefore	therefore	RB
cord-298458-p7rvupjo	168	2	,	,	,
cord-298458-p7rvupjo	168	3	it	-PRON-	PRP
cord-298458-p7rvupjo	168	4	is	be	VBZ
cord-298458-p7rvupjo	168	5	possible	possible	JJ
cord-298458-p7rvupjo	168	6	that	that	IN
cord-298458-p7rvupjo	168	7	TRM	TRM	NNP
cord-298458-p7rvupjo	168	8	-	-	HYPH
cord-298458-p7rvupjo	168	9	mediated	mediate	VBN
cord-298458-p7rvupjo	168	10	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	168	11	protection	protection	NN
cord-298458-p7rvupjo	168	12	could	could	MD
cord-298458-p7rvupjo	168	13	be	be	VB
cord-298458-p7rvupjo	168	14	re	re	VBN
cord-298458-p7rvupjo	168	15	-	-	VBN
cord-298458-p7rvupjo	168	16	established	establish	VBN
cord-298458-p7rvupjo	168	17	by	by	IN
cord-298458-p7rvupjo	168	18	vaccination	vaccination	NN
cord-298458-p7rvupjo	168	19	after	after	IN
cord-298458-p7rvupjo	168	20	a	a	DT
cord-298458-p7rvupjo	168	21	waning	waning	NN
cord-298458-p7rvupjo	168	22	of	of	IN
cord-298458-p7rvupjo	168	23	the	the	DT
cord-298458-p7rvupjo	168	24	protective	protective	JJ
cord-298458-p7rvupjo	168	25	TRM	TRM	NNP
cord-298458-p7rvupjo	168	26	population	population	NN
cord-298458-p7rvupjo	168	27	in	in	IN
cord-298458-p7rvupjo	168	28	the	the	DT
cord-298458-p7rvupjo	168	29	lung	lung	NN
cord-298458-p7rvupjo	168	30	.	.	.
cord-298458-p7rvupjo	169	1	While	while	IN
cord-298458-p7rvupjo	169	2	protection	protection	NN
cord-298458-p7rvupjo	169	3	in	in	IN
cord-298458-p7rvupjo	169	4	mouse	mouse	NN
cord-298458-p7rvupjo	169	5	models	model	NNS
cord-298458-p7rvupjo	169	6	is	be	VBZ
cord-298458-p7rvupjo	169	7	well	well	RB
cord-298458-p7rvupjo	169	8	established	establish	VBN
cord-298458-p7rvupjo	169	9	,	,	,
cord-298458-p7rvupjo	169	10	whether	whether	IN
cord-298458-p7rvupjo	169	11	memory	memory	NN
cord-298458-p7rvupjo	169	12	CD8	CD8	NNP
cord-298458-p7rvupjo	169	13	T	T	NNP
cord-298458-p7rvupjo	169	14	cells	cell	NNS
cord-298458-p7rvupjo	169	15	play	play	VBP
cord-298458-p7rvupjo	169	16	a	a	DT
cord-298458-p7rvupjo	169	17	critical	critical	JJ
cord-298458-p7rvupjo	169	18	role	role	NN
cord-298458-p7rvupjo	169	19	in	in	IN
cord-298458-p7rvupjo	169	20	protection	protection	NN
cord-298458-p7rvupjo	169	21	following	follow	VBG
cord-298458-p7rvupjo	169	22	secondary	secondary	JJ
cord-298458-p7rvupjo	169	23	respiratory	respiratory	JJ
cord-298458-p7rvupjo	169	24	infection	infection	NN
cord-298458-p7rvupjo	169	25	in	in	IN
cord-298458-p7rvupjo	169	26	humans	human	NNS
cord-298458-p7rvupjo	169	27	is	be	VBZ
cord-298458-p7rvupjo	169	28	currently	currently	RB
cord-298458-p7rvupjo	169	29	unclear	unclear	JJ
cord-298458-p7rvupjo	169	30	.	.	.
cord-298458-p7rvupjo	170	1	Similar	similar	JJ
cord-298458-p7rvupjo	170	2	to	to	IN
cord-298458-p7rvupjo	170	3	studies	study	NNS
cord-298458-p7rvupjo	170	4	in	in	IN
cord-298458-p7rvupjo	170	5	murine	murine	JJ
cord-298458-p7rvupjo	170	6	models	model	NNS
cord-298458-p7rvupjo	170	7	,	,	,
cord-298458-p7rvupjo	170	8	evidence	evidence	NN
cord-298458-p7rvupjo	170	9	for	for	IN
cord-298458-p7rvupjo	170	10	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	170	11	immunity	immunity	NN
cord-298458-p7rvupjo	170	12	mediated	mediate	VBN
cord-298458-p7rvupjo	170	13	by	by	IN
cord-298458-p7rvupjo	170	14	memory	memory	NN
cord-298458-p7rvupjo	170	15	CD8	CD8	NNP
cord-298458-p7rvupjo	170	16	T	T	NNP
cord-298458-p7rvupjo	170	17	cells	cell	NNS
cord-298458-p7rvupjo	170	18	has	have	VBZ
cord-298458-p7rvupjo	170	19	also	also	RB
cord-298458-p7rvupjo	170	20	been	be	VBN
cord-298458-p7rvupjo	170	21	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	170	22	in	in	IN
cord-298458-p7rvupjo	170	23	humans	human	NNS
cord-298458-p7rvupjo	170	24	.	.	.
cord-298458-p7rvupjo	171	1	Individuals	individual	NNS
cord-298458-p7rvupjo	171	2	lacking	lack	VBG
cord-298458-p7rvupjo	171	3	H1N1-specific	h1n1-specific	NN
cord-298458-p7rvupjo	171	4	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	171	5	antibody	antibody	NN
cord-298458-p7rvupjo	171	6	titers	titer	NNS
cord-298458-p7rvupjo	171	7	exhibited	exhibit	VBD
cord-298458-p7rvupjo	171	8	an	an	DT
cord-298458-p7rvupjo	171	9	inverse	inverse	JJ
cord-298458-p7rvupjo	171	10	correlation	correlation	NN
cord-298458-p7rvupjo	171	11	between	between	IN
cord-298458-p7rvupjo	171	12	memory	memory	NN
cord-298458-p7rvupjo	171	13	CD8	CD8	NNP
cord-298458-p7rvupjo	171	14	T	T	NNP
cord-298458-p7rvupjo	171	15	cell	cell	NN
cord-298458-p7rvupjo	171	16	activity	activity	NN
cord-298458-p7rvupjo	171	17	and	and	CC
cord-298458-p7rvupjo	171	18	viral	viral	JJ
cord-298458-p7rvupjo	171	19	shedding	shedding	NN
cord-298458-p7rvupjo	171	20	following	follow	VBG
cord-298458-p7rvupjo	171	21	their	-PRON-	PRP$
cord-298458-p7rvupjo	171	22	first	first	JJ
cord-298458-p7rvupjo	171	23	exposure	exposure	NN
cord-298458-p7rvupjo	171	24	with	with	IN
cord-298458-p7rvupjo	171	25	H1N1	H1N1	NNP
cord-298458-p7rvupjo	171	26	IAV	IAV	NNP
cord-298458-p7rvupjo	171	27	(	(	-LRB-
cord-298458-p7rvupjo	171	28	93	93	CD
cord-298458-p7rvupjo	171	29	)	)	-RRB-
cord-298458-p7rvupjo	171	30	.	.	.
cord-298458-p7rvupjo	172	1	More	more	RBR
cord-298458-p7rvupjo	172	2	recently	recently	RB
cord-298458-p7rvupjo	172	3	,	,	,
cord-298458-p7rvupjo	172	4	it	-PRON-	PRP
cord-298458-p7rvupjo	172	5	was	be	VBD
cord-298458-p7rvupjo	172	6	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	172	7	that	that	IN
cord-298458-p7rvupjo	172	8	the	the	DT
cord-298458-p7rvupjo	172	9	frequencies	frequency	NNS
cord-298458-p7rvupjo	172	10	of	of	IN
cord-298458-p7rvupjo	172	11	pre	pre	JJ
cord-298458-p7rvupjo	172	12	-	-	JJ
cord-298458-p7rvupjo	172	13	existing	existing	JJ
cord-298458-p7rvupjo	172	14	crossreactive	crossreactive	JJ
cord-298458-p7rvupjo	172	15	memory	memory	NN
cord-298458-p7rvupjo	172	16	CD8	CD8	NNP
cord-298458-p7rvupjo	172	17	T	T	NNP
cord-298458-p7rvupjo	172	18	cells	cell	NNS
cord-298458-p7rvupjo	172	19	correlated	correlate	VBN
cord-298458-p7rvupjo	172	20	with	with	IN
cord-298458-p7rvupjo	172	21	reduced	reduce	VBN
cord-298458-p7rvupjo	172	22	symptoms	symptom	NNS
cord-298458-p7rvupjo	172	23	,	,	,
cord-298458-p7rvupjo	172	24	including	include	VBG
cord-298458-p7rvupjo	172	25	fewer	few	JJR
cord-298458-p7rvupjo	172	26	patients	patient	NNS
cord-298458-p7rvupjo	172	27	with	with	IN
cord-298458-p7rvupjo	172	28	fever	fever	NN
cord-298458-p7rvupjo	172	29	,	,	,
cord-298458-p7rvupjo	172	30	sore	sore	JJ
cord-298458-p7rvupjo	172	31	throat	throat	NN
cord-298458-p7rvupjo	172	32	,	,	,
cord-298458-p7rvupjo	172	33	and	and	CC
cord-298458-p7rvupjo	172	34	cough	cough	NN
cord-298458-p7rvupjo	172	35	,	,	,
cord-298458-p7rvupjo	172	36	following	follow	VBG
cord-298458-p7rvupjo	172	37	infection	infection	NN
cord-298458-p7rvupjo	172	38	with	with	IN
cord-298458-p7rvupjo	172	39	the	the	DT
cord-298458-p7rvupjo	172	40	2009	2009	CD
cord-298458-p7rvupjo	172	41	pandemic	pandemic	NN
cord-298458-p7rvupjo	172	42	H1N1	H1N1	NNP
cord-298458-p7rvupjo	172	43	IAV	IAV	NNP
cord-298458-p7rvupjo	172	44	strain	strain	NN
cord-298458-p7rvupjo	172	45	(	(	-LRB-
cord-298458-p7rvupjo	172	46	50	50	CD
cord-298458-p7rvupjo	172	47	)	)	-RRB-
cord-298458-p7rvupjo	172	48	.	.	.
cord-298458-p7rvupjo	173	1	Similarly	similarly	RB
cord-298458-p7rvupjo	173	2	,	,	,
cord-298458-p7rvupjo	173	3	a	a	DT
cord-298458-p7rvupjo	173	4	correlation	correlation	NN
cord-298458-p7rvupjo	173	5	between	between	IN
cord-298458-p7rvupjo	173	6	pre	pre	JJ
cord-298458-p7rvupjo	173	7	-	-	JJ
cord-298458-p7rvupjo	173	8	existing	existing	JJ
cord-298458-p7rvupjo	173	9	H3N2-specific	H3N2-specific	NNP
cord-298458-p7rvupjo	173	10	memory	memory	NN
cord-298458-p7rvupjo	173	11	CD8	CD8	NNP
cord-298458-p7rvupjo	173	12	T	T	NNP
cord-298458-p7rvupjo	173	13	cells	cell	NNS
cord-298458-p7rvupjo	173	14	and	and	CC
cord-298458-p7rvupjo	173	15	reduced	reduce	VBN
cord-298458-p7rvupjo	173	16	risk	risk	NN
cord-298458-p7rvupjo	173	17	of	of	IN
cord-298458-p7rvupjo	173	18	viral	viral	JJ
cord-298458-p7rvupjo	173	19	shedding	shed	VBG
cord-298458-p7rvupjo	173	20	following	follow	VBG
cord-298458-p7rvupjo	173	21	2009	2009	CD
cord-298458-p7rvupjo	173	22	pandemic	pandemic	NN
cord-298458-p7rvupjo	173	23	H1N1	H1N1	NNP
cord-298458-p7rvupjo	173	24	IAV	IAV	NNP
cord-298458-p7rvupjo	173	25	infection	infection	NN
cord-298458-p7rvupjo	173	26	was	be	VBD
cord-298458-p7rvupjo	173	27	observed	observe	VBN
cord-298458-p7rvupjo	173	28	(	(	-LRB-
cord-298458-p7rvupjo	173	29	115	115	CD
cord-298458-p7rvupjo	173	30	)	)	-RRB-
cord-298458-p7rvupjo	173	31	.	.	.
cord-298458-p7rvupjo	174	1	Thus	thus	RB
cord-298458-p7rvupjo	174	2	,	,	,
cord-298458-p7rvupjo	174	3	memory	memory	NN
cord-298458-p7rvupjo	174	4	CD8	CD8	NNP
cord-298458-p7rvupjo	174	5	T	T	NNP
cord-298458-p7rvupjo	174	6	cell	cell	NN
cord-298458-p7rvupjo	174	7	-	-	HYPH
cord-298458-p7rvupjo	174	8	mediated	mediate	VBN
cord-298458-p7rvupjo	174	9	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	174	10	protection	protection	NN
cord-298458-p7rvupjo	174	11	is	be	VBZ
cord-298458-p7rvupjo	174	12	also	also	RB
cord-298458-p7rvupjo	174	13	likely	likely	JJ
cord-298458-p7rvupjo	174	14	to	to	TO
cord-298458-p7rvupjo	174	15	be	be	VB
cord-298458-p7rvupjo	174	16	critical	critical	JJ
cord-298458-p7rvupjo	174	17	in	in	IN
cord-298458-p7rvupjo	174	18	humans	human	NNS
cord-298458-p7rvupjo	174	19	.	.	.
cord-298458-p7rvupjo	175	1	Following	follow	VBG
cord-298458-p7rvupjo	175	2	experimental	experimental	JJ
cord-298458-p7rvupjo	175	3	RSV	rsv	NN
cord-298458-p7rvupjo	175	4	infection	infection	NN
cord-298458-p7rvupjo	175	5	in	in	IN
cord-298458-p7rvupjo	175	6	humans	human	NNS
cord-298458-p7rvupjo	175	7	,	,	,
cord-298458-p7rvupjo	175	8	the	the	DT
cord-298458-p7rvupjo	175	9	frequency	frequency	NN
cord-298458-p7rvupjo	175	10	of	of	IN
cord-298458-p7rvupjo	175	11	pre	pre	JJ
cord-298458-p7rvupjo	175	12	-	-	JJ
cord-298458-p7rvupjo	175	13	existing	existing	JJ
cord-298458-p7rvupjo	175	14	RSV	RSV	NNP
cord-298458-p7rvupjo	175	15	-	-	HYPH
cord-298458-p7rvupjo	175	16	specific	specific	JJ
cord-298458-p7rvupjo	175	17	memory	memory	NN
cord-298458-p7rvupjo	175	18	CD8	CD8	NNP
cord-298458-p7rvupjo	175	19	T	T	NNP
cord-298458-p7rvupjo	175	20	cells	cell	NNS
cord-298458-p7rvupjo	175	21	in	in	IN
cord-298458-p7rvupjo	175	22	the	the	DT
cord-298458-p7rvupjo	175	23	airways	airways	NNP
cord-298458-p7rvupjo	175	24	correlates	correlate	VBZ
cord-298458-p7rvupjo	175	25	with	with	IN
cord-298458-p7rvupjo	175	26	a	a	DT
cord-298458-p7rvupjo	175	27	reduction	reduction	NN
cord-298458-p7rvupjo	175	28	in	in	IN
cord-298458-p7rvupjo	175	29	both	both	CC
cord-298458-p7rvupjo	175	30	cumulative	cumulative	JJ
cord-298458-p7rvupjo	175	31	and	and	CC
cord-298458-p7rvupjo	175	32	lower	low	JJR
cord-298458-p7rvupjo	175	33	respiratory	respiratory	JJ
cord-298458-p7rvupjo	175	34	tract	tract	NN
cord-298458-p7rvupjo	175	35	symptom	symptom	NN
cord-298458-p7rvupjo	175	36	scores	score	NNS
cord-298458-p7rvupjo	175	37	,	,	,
cord-298458-p7rvupjo	175	38	suggesting	suggest	VBG
cord-298458-p7rvupjo	175	39	a	a	DT
cord-298458-p7rvupjo	175	40	possible	possible	JJ
cord-298458-p7rvupjo	175	41	role	role	NN
cord-298458-p7rvupjo	175	42	for	for	IN
cord-298458-p7rvupjo	175	43	memory	memory	NN
cord-298458-p7rvupjo	175	44	CD8	CD8	NNP
cord-298458-p7rvupjo	175	45	T	T	NNP
cord-298458-p7rvupjo	175	46	cells	cell	NNS
cord-298458-p7rvupjo	175	47	in	in	IN
cord-298458-p7rvupjo	175	48	protection	protection	NN
cord-298458-p7rvupjo	175	49	against	against	IN
cord-298458-p7rvupjo	175	50	RSV	RSV	NNP
cord-298458-p7rvupjo	175	51	in	in	IN
cord-298458-p7rvupjo	175	52	humans	human	NNS
cord-298458-p7rvupjo	175	53	(	(	-LRB-
cord-298458-p7rvupjo	175	54	49	49	CD
cord-298458-p7rvupjo	175	55	)	)	-RRB-
cord-298458-p7rvupjo	175	56	.	.	.
cord-298458-p7rvupjo	176	1	However	however	RB
cord-298458-p7rvupjo	176	2	,	,	,
cord-298458-p7rvupjo	176	3	evidence	evidence	NN
cord-298458-p7rvupjo	176	4	has	have	VBZ
cord-298458-p7rvupjo	176	5	also	also	RB
cord-298458-p7rvupjo	176	6	been	be	VBN
cord-298458-p7rvupjo	176	7	provided	provide	VBN
cord-298458-p7rvupjo	176	8	suggesting	suggest	VBG
cord-298458-p7rvupjo	176	9	that	that	IN
cord-298458-p7rvupjo	176	10	memory	memory	NN
cord-298458-p7rvupjo	176	11	CD8	CD8	NNP
cord-298458-p7rvupjo	176	12	T	T	NNP
cord-298458-p7rvupjo	176	13	cells	cell	NNS
cord-298458-p7rvupjo	176	14	may	may	MD
cord-298458-p7rvupjo	176	15	not	not	RB
cord-298458-p7rvupjo	176	16	contribute	contribute	VB
cord-298458-p7rvupjo	176	17	to	to	IN
cord-298458-p7rvupjo	176	18	protection	protection	NN
cord-298458-p7rvupjo	176	19	following	follow	VBG
cord-298458-p7rvupjo	176	20	respiratory	respiratory	JJ
cord-298458-p7rvupjo	176	21	virus	virus	NN
cord-298458-p7rvupjo	176	22	infections	infection	NNS
cord-298458-p7rvupjo	176	23	in	in	IN
cord-298458-p7rvupjo	176	24	humans	human	NNS
cord-298458-p7rvupjo	176	25	.	.	.
cord-298458-p7rvupjo	177	1	Natural	natural	JJ
cord-298458-p7rvupjo	177	2	reinfection	reinfection	NN
cord-298458-p7rvupjo	177	3	of	of	IN
cord-298458-p7rvupjo	177	4	infants	infant	NNS
cord-298458-p7rvupjo	177	5	with	with	IN
cord-298458-p7rvupjo	177	6	RSV	RSV	NNP
cord-298458-p7rvupjo	177	7	did	do	VBD
cord-298458-p7rvupjo	177	8	not	not	RB
cord-298458-p7rvupjo	177	9	result	result	VB
cord-298458-p7rvupjo	177	10	in	in	IN
cord-298458-p7rvupjo	177	11	a	a	DT
cord-298458-p7rvupjo	177	12	boosting	boosting	NN
cord-298458-p7rvupjo	177	13	of	of	IN
cord-298458-p7rvupjo	177	14	the	the	DT
cord-298458-p7rvupjo	177	15	CD8	CD8	NNP
cord-298458-p7rvupjo	177	16	T	T	NNP
cord-298458-p7rvupjo	177	17	cell	cell	NN
cord-298458-p7rvupjo	177	18	response	response	NN
cord-298458-p7rvupjo	177	19	(	(	-LRB-
cord-298458-p7rvupjo	177	20	116	116	CD
cord-298458-p7rvupjo	177	21	)	)	-RRB-
cord-298458-p7rvupjo	177	22	.	.	.
cord-298458-p7rvupjo	178	1	Similarly	similarly	RB
cord-298458-p7rvupjo	178	2	,	,	,
cord-298458-p7rvupjo	178	3	the	the	DT
cord-298458-p7rvupjo	178	4	frequency	frequency	NN
cord-298458-p7rvupjo	178	5	of	of	IN
cord-298458-p7rvupjo	178	6	RSV	RSV	NNP
cord-298458-p7rvupjo	178	7	-	-	HYPH
cord-298458-p7rvupjo	178	8	specific	specific	JJ
cord-298458-p7rvupjo	178	9	memory	memory	NN
cord-298458-p7rvupjo	178	10	CD8	CD8	NNP
cord-298458-p7rvupjo	178	11	T	T	NNP
cord-298458-p7rvupjo	178	12	cells	cell	NNS
cord-298458-p7rvupjo	178	13	in	in	IN
cord-298458-p7rvupjo	178	14	the	the	DT
cord-298458-p7rvupjo	178	15	peripheral	peripheral	JJ
cord-298458-p7rvupjo	178	16	blood	blood	NN
cord-298458-p7rvupjo	178	17	of	of	IN
cord-298458-p7rvupjo	178	18	healthy	healthy	JJ
cord-298458-p7rvupjo	178	19	adults	adult	NNS
cord-298458-p7rvupjo	178	20	is	be	VBZ
cord-298458-p7rvupjo	178	21	significantly	significantly	RB
cord-298458-p7rvupjo	178	22	reduced	reduce	VBN
cord-298458-p7rvupjo	178	23	compared	compare	VBN
cord-298458-p7rvupjo	178	24	to	to	IN
cord-298458-p7rvupjo	178	25	IAVspecific	iavspecific	JJ
cord-298458-p7rvupjo	178	26	memory	memory	NN
cord-298458-p7rvupjo	178	27	CD8	CD8	NNP
cord-298458-p7rvupjo	178	28	T	T	NNP
cord-298458-p7rvupjo	178	29	cells	cell	NNS
cord-298458-p7rvupjo	178	30	(	(	-LRB-
cord-298458-p7rvupjo	178	31	57	57	CD
cord-298458-p7rvupjo	178	32	)	)	-RRB-
cord-298458-p7rvupjo	178	33	.	.	.
cord-298458-p7rvupjo	179	1	Therefore	therefore	RB
cord-298458-p7rvupjo	179	2	,	,	,
cord-298458-p7rvupjo	179	3	the	the	DT
cord-298458-p7rvupjo	179	4	extent	extent	NN
cord-298458-p7rvupjo	179	5	to	to	TO
cord-298458-p7rvupjo	179	6	which	which	WDT
cord-298458-p7rvupjo	179	7	memory	memory	NN
cord-298458-p7rvupjo	179	8	CD8	CD8	NNP
cord-298458-p7rvupjo	179	9	T	T	NNP
cord-298458-p7rvupjo	179	10	cells	cell	NNS
cord-298458-p7rvupjo	179	11	play	play	VBP
cord-298458-p7rvupjo	179	12	a	a	DT
cord-298458-p7rvupjo	179	13	role	role	NN
cord-298458-p7rvupjo	179	14	in	in	IN
cord-298458-p7rvupjo	179	15	providing	provide	VBG
cord-298458-p7rvupjo	179	16	protection	protection	NN
cord-298458-p7rvupjo	179	17	against	against	IN
cord-298458-p7rvupjo	179	18	RSV	RSV	NNP
cord-298458-p7rvupjo	179	19	infection	infection	NN
cord-298458-p7rvupjo	179	20	in	in	IN
cord-298458-p7rvupjo	179	21	humans	human	NNS
cord-298458-p7rvupjo	179	22	remains	remain	VBZ
cord-298458-p7rvupjo	179	23	unclear	unclear	JJ
cord-298458-p7rvupjo	179	24	.	.	.
cord-298458-p7rvupjo	180	1	Despite	despite	IN
cord-298458-p7rvupjo	180	2	their	-PRON-	PRP$
cord-298458-p7rvupjo	180	3	beneficial	beneficial	JJ
cord-298458-p7rvupjo	180	4	role	role	NN
cord-298458-p7rvupjo	180	5	in	in	IN
cord-298458-p7rvupjo	180	6	mediating	mediate	VBG
cord-298458-p7rvupjo	180	7	viral	viral	JJ
cord-298458-p7rvupjo	180	8	clearance	clearance	NN
cord-298458-p7rvupjo	180	9	and	and	CC
cord-298458-p7rvupjo	180	10	protecting	protect	VBG
cord-298458-p7rvupjo	180	11	against	against	IN
cord-298458-p7rvupjo	180	12	secondary	secondary	JJ
cord-298458-p7rvupjo	180	13	infection	infection	NN
cord-298458-p7rvupjo	180	14	,	,	,
cord-298458-p7rvupjo	180	15	CD8	CD8	NNP
cord-298458-p7rvupjo	180	16	T	T	NNP
cord-298458-p7rvupjo	180	17	cells	cell	NNS
cord-298458-p7rvupjo	180	18	have	have	VBP
cord-298458-p7rvupjo	180	19	also	also	RB
cord-298458-p7rvupjo	180	20	been	be	VBN
cord-298458-p7rvupjo	180	21	associated	associate	VBN
cord-298458-p7rvupjo	180	22	with	with	IN
cord-298458-p7rvupjo	180	23	the	the	DT
cord-298458-p7rvupjo	180	24	induction	induction	NN
cord-298458-p7rvupjo	180	25	of	of	IN
cord-298458-p7rvupjo	180	26	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	180	27	following	follow	VBG
cord-298458-p7rvupjo	180	28	respiratory	respiratory	JJ
cord-298458-p7rvupjo	180	29	virus	virus	NN
cord-298458-p7rvupjo	180	30	infection	infection	NN
cord-298458-p7rvupjo	180	31	.	.	.
cord-298458-p7rvupjo	181	1	Although	although	IN
cord-298458-p7rvupjo	181	2	mice	mouse	NNS
cord-298458-p7rvupjo	181	3	depleted	deplete	VBN
cord-298458-p7rvupjo	181	4	of	of	IN
cord-298458-p7rvupjo	181	5	CD8	CD8	NNP
cord-298458-p7rvupjo	181	6	T	T	NNP
cord-298458-p7rvupjo	181	7	cells	cell	NNS
cord-298458-p7rvupjo	181	8	exhibited	exhibit	VBD
cord-298458-p7rvupjo	181	9	elevated	elevated	JJ
cord-298458-p7rvupjo	181	10	lung	lung	NN
cord-298458-p7rvupjo	181	11	viral	viral	JJ
cord-298458-p7rvupjo	181	12	titers	titer	NNS
cord-298458-p7rvupjo	181	13	,	,	,
cord-298458-p7rvupjo	181	14	weight	weight	NN
cord-298458-p7rvupjo	181	15	loss	loss	NN
cord-298458-p7rvupjo	181	16	and	and	CC
cord-298458-p7rvupjo	181	17	symptom	symptom	NN
cord-298458-p7rvupjo	181	18	illness	illness	NN
cord-298458-p7rvupjo	181	19	scores	score	NNS
cord-298458-p7rvupjo	181	20	were	be	VBD
cord-298458-p7rvupjo	181	21	significantly	significantly	RB
cord-298458-p7rvupjo	181	22	reduced	reduce	VBN
cord-298458-p7rvupjo	181	23	in	in	IN
cord-298458-p7rvupjo	181	24	CD8	CD8	NNP
cord-298458-p7rvupjo	181	25	T	T	NNP
cord-298458-p7rvupjo	181	26	cell	cell	NN
cord-298458-p7rvupjo	181	27	depleted	deplete	VBD
cord-298458-p7rvupjo	181	28	mice	mouse	NNS
cord-298458-p7rvupjo	181	29	following	follow	VBG
cord-298458-p7rvupjo	181	30	acute	acute	JJ
cord-298458-p7rvupjo	181	31	RSV	RSV	NNP
cord-298458-p7rvupjo	181	32	infection	infection	NN
cord-298458-p7rvupjo	181	33	(	(	-LRB-
cord-298458-p7rvupjo	181	34	26	26	CD
cord-298458-p7rvupjo	181	35	)	)	-RRB-
cord-298458-p7rvupjo	181	36	.	.	.
cord-298458-p7rvupjo	182	1	Similarly	similarly	RB
cord-298458-p7rvupjo	182	2	,	,	,
cord-298458-p7rvupjo	182	3	the	the	DT
cord-298458-p7rvupjo	182	4	adoptive	adoptive	JJ
cord-298458-p7rvupjo	182	5	transfer	transfer	NN
cord-298458-p7rvupjo	182	6	of	of	IN
cord-298458-p7rvupjo	182	7	CD8	CD8	NNP
cord-298458-p7rvupjo	182	8	T	T	NNP
cord-298458-p7rvupjo	182	9	cell	cell	NN
cord-298458-p7rvupjo	182	10	lines	line	NNS
cord-298458-p7rvupjo	182	11	exacerbated	exacerbate	VBD
cord-298458-p7rvupjo	182	12	weight	weight	NN
cord-298458-p7rvupjo	182	13	loss	loss	NN
cord-298458-p7rvupjo	182	14	following	follow	VBG
cord-298458-p7rvupjo	182	15	an	an	DT
cord-298458-p7rvupjo	182	16	acute	acute	JJ
cord-298458-p7rvupjo	182	17	RSV	RSV	NNP
cord-298458-p7rvupjo	182	18	infection	infection	NN
cord-298458-p7rvupjo	182	19	,	,	,
cord-298458-p7rvupjo	182	20	despite	despite	IN
cord-298458-p7rvupjo	182	21	accelerating	accelerate	VBG
cord-298458-p7rvupjo	182	22	viral	viral	JJ
cord-298458-p7rvupjo	182	23	clearance	clearance	NN
cord-298458-p7rvupjo	182	24	(	(	-LRB-
cord-298458-p7rvupjo	182	25	82	82	CD
cord-298458-p7rvupjo	182	26	)	)	-RRB-
cord-298458-p7rvupjo	182	27	(	(	-LRB-
cord-298458-p7rvupjo	182	28	83	83	CD
cord-298458-p7rvupjo	182	29	)	)	-RRB-
cord-298458-p7rvupjo	182	30	(	(	-LRB-
cord-298458-p7rvupjo	182	31	84	84	CD
cord-298458-p7rvupjo	182	32	)	)	-RRB-
cord-298458-p7rvupjo	182	33	.	.	.
cord-298458-p7rvupjo	183	1	Similar	similar	JJ
cord-298458-p7rvupjo	183	2	reduction	reduction	NN
cord-298458-p7rvupjo	183	3	in	in	IN
cord-298458-p7rvupjo	183	4	disease	disease	NN
cord-298458-p7rvupjo	183	5	severity	severity	NN
cord-298458-p7rvupjo	183	6	was	be	VBD
cord-298458-p7rvupjo	183	7	also	also	RB
cord-298458-p7rvupjo	183	8	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	183	9	following	follow	VBG
cord-298458-p7rvupjo	183	10	either	either	CC
cord-298458-p7rvupjo	183	11	HMPV	HMPV	NNP
cord-298458-p7rvupjo	183	12	or	or	CC
cord-298458-p7rvupjo	183	13	PVM	PVM	NNP
cord-298458-p7rvupjo	183	14	infection	infection	NN
cord-298458-p7rvupjo	183	15	of	of	IN
cord-298458-p7rvupjo	183	16	CD8	CD8	NNP
cord-298458-p7rvupjo	183	17	T	T	NNP
cord-298458-p7rvupjo	183	18	cell	cell	NN
cord-298458-p7rvupjo	183	19	depleted	deplete	VBD
cord-298458-p7rvupjo	183	20	mice	mouse	NNS
cord-298458-p7rvupjo	183	21	or	or	CC
cord-298458-p7rvupjo	183	22	mice	mouse	NNS
cord-298458-p7rvupjo	183	23	genetically	genetically	RB
cord-298458-p7rvupjo	183	24	deficient	deficient	JJ
cord-298458-p7rvupjo	183	25	in	in	IN
cord-298458-p7rvupjo	183	26	CD8	CD8	NNP
cord-298458-p7rvupjo	183	27	T	T	NNP
cord-298458-p7rvupjo	183	28	cells	cell	NNS
cord-298458-p7rvupjo	183	29	,	,	,
cord-298458-p7rvupjo	183	30	respectively	respectively	RB
cord-298458-p7rvupjo	183	31	(	(	-LRB-
cord-298458-p7rvupjo	183	32	40	40	CD
cord-298458-p7rvupjo	183	33	,	,	,
cord-298458-p7rvupjo	183	34	103	103	CD
cord-298458-p7rvupjo	183	35	)	)	-RRB-
cord-298458-p7rvupjo	183	36	.	.	.
cord-298458-p7rvupjo	184	1	In	in	IN
cord-298458-p7rvupjo	184	2	addition	addition	NN
cord-298458-p7rvupjo	184	3	to	to	IN
cord-298458-p7rvupjo	184	4	the	the	DT
cord-298458-p7rvupjo	184	5	induction	induction	NN
cord-298458-p7rvupjo	184	6	of	of	IN
cord-298458-p7rvupjo	184	7	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	184	8	following	follow	VBG
cord-298458-p7rvupjo	184	9	acute	acute	JJ
cord-298458-p7rvupjo	184	10	respiratory	respiratory	JJ
cord-298458-p7rvupjo	184	11	virus	virus	NN
cord-298458-p7rvupjo	184	12	infections	infection	NNS
cord-298458-p7rvupjo	184	13	,	,	,
cord-298458-p7rvupjo	184	14	we	-PRON-	PRP
cord-298458-p7rvupjo	184	15	recently	recently	RB
cord-298458-p7rvupjo	184	16	demonstrated	demonstrate	VBD
cord-298458-p7rvupjo	184	17	that	that	IN
cord-298458-p7rvupjo	184	18	memory	memory	NN
cord-298458-p7rvupjo	184	19	CD8	CD8	NNP
cord-298458-p7rvupjo	184	20	T	T	NNP
cord-298458-p7rvupjo	184	21	cells	cell	NNS
cord-298458-p7rvupjo	184	22	also	also	RB
cord-298458-p7rvupjo	184	23	mediate	mediate	VBP
cord-298458-p7rvupjo	184	24	severe	severe	JJ
cord-298458-p7rvupjo	184	25	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	184	26	following	follow	VBG
cord-298458-p7rvupjo	184	27	secondary	secondary	JJ
cord-298458-p7rvupjo	184	28	RSV	RSV	NNP
cord-298458-p7rvupjo	184	29	infection	infection	NN
cord-298458-p7rvupjo	184	30	(	(	-LRB-
cord-298458-p7rvupjo	184	31	30	30	CD
cord-298458-p7rvupjo	184	32	)	)	-RRB-
cord-298458-p7rvupjo	184	33	.	.	.
cord-298458-p7rvupjo	185	1	Large	large	JJ
cord-298458-p7rvupjo	185	2	frequencies	frequency	NNS
cord-298458-p7rvupjo	185	3	of	of	IN
cord-298458-p7rvupjo	185	4	systemic	systemic	JJ
cord-298458-p7rvupjo	185	5	,	,	,
cord-298458-p7rvupjo	185	6	pre	pre	JJ
cord-298458-p7rvupjo	185	7	-	-	JJ
cord-298458-p7rvupjo	185	8	existing	existing	JJ
cord-298458-p7rvupjo	185	9	RSV	rsv	NN
cord-298458-p7rvupjo	185	10	-	-	HYPH
cord-298458-p7rvupjo	185	11	specific	specific	JJ
cord-298458-p7rvupjo	185	12	memory	memory	NN
cord-298458-p7rvupjo	185	13	CD8	CD8	NNP
cord-298458-p7rvupjo	185	14	T	T	NNP
cord-298458-p7rvupjo	185	15	cells	cell	NNS
cord-298458-p7rvupjo	185	16	generated	generate	VBN
cord-298458-p7rvupjo	185	17	through	through	IN
cord-298458-p7rvupjo	185	18	DC	DC	NNP
cord-298458-p7rvupjo	185	19	-	-	HYPH
cord-298458-p7rvupjo	185	20	LM	LM	NNP
cord-298458-p7rvupjo	185	21	immunization	immunization	NN
cord-298458-p7rvupjo	185	22	induced	induce	VBD
cord-298458-p7rvupjo	185	23	significant	significant	JJ
cord-298458-p7rvupjo	185	24	weight	weight	NN
cord-298458-p7rvupjo	185	25	loss	loss	NN
cord-298458-p7rvupjo	185	26	,	,	,
cord-298458-p7rvupjo	185	27	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	185	28	dysfunction	dysfunction	NN
cord-298458-p7rvupjo	185	29	,	,	,
cord-298458-p7rvupjo	185	30	and	and	CC
cord-298458-p7rvupjo	185	31	mortality	mortality	NN
cord-298458-p7rvupjo	185	32	following	follow	VBG
cord-298458-p7rvupjo	185	33	RSV	RSV	NNP
cord-298458-p7rvupjo	185	34	challenge	challenge	NN
cord-298458-p7rvupjo	185	35	,	,	,
cord-298458-p7rvupjo	185	36	despite	despite	IN
cord-298458-p7rvupjo	185	37	a	a	DT
cord-298458-p7rvupjo	185	38	significant	significant	JJ
cord-298458-p7rvupjo	185	39	reduction	reduction	NN
cord-298458-p7rvupjo	185	40	in	in	IN
cord-298458-p7rvupjo	185	41	lung	lung	NN
cord-298458-p7rvupjo	185	42	viral	viral	JJ
cord-298458-p7rvupjo	185	43	titers	titer	NNS
cord-298458-p7rvupjo	185	44	.	.	.
cord-298458-p7rvupjo	186	1	This	this	DT
cord-298458-p7rvupjo	186	2	result	result	NN
cord-298458-p7rvupjo	186	3	was	be	VBD
cord-298458-p7rvupjo	186	4	in	in	IN
cord-298458-p7rvupjo	186	5	contrast	contrast	NN
cord-298458-p7rvupjo	186	6	to	to	IN
cord-298458-p7rvupjo	186	7	studies	study	NNS
cord-298458-p7rvupjo	186	8	using	use	VBG
cord-298458-p7rvupjo	186	9	similar	similar	JJ
cord-298458-p7rvupjo	186	10	immunization	immunization	NN
cord-298458-p7rvupjo	186	11	strategies	strategy	NNS
cord-298458-p7rvupjo	186	12	to	to	IN
cord-298458-p7rvupjo	186	13	either	either	CC
cord-298458-p7rvupjo	186	14	IAV	IAV	NNP
cord-298458-p7rvupjo	186	15	or	or	CC
cord-298458-p7rvupjo	186	16	SARS	SARS	NNP
cord-298458-p7rvupjo	186	17	,	,	,
cord-298458-p7rvupjo	186	18	in	in	IN
cord-298458-p7rvupjo	186	19	which	which	WDT
cord-298458-p7rvupjo	186	20	memory	memory	NN
cord-298458-p7rvupjo	186	21	CD8	CD8	NNP
cord-298458-p7rvupjo	186	22	T	T	NNP
cord-298458-p7rvupjo	186	23	cells	cell	NNS
cord-298458-p7rvupjo	186	24	mediated	mediate	VBD
cord-298458-p7rvupjo	186	25	protection	protection	NN
cord-298458-p7rvupjo	186	26	against	against	IN
cord-298458-p7rvupjo	186	27	lethal	lethal	JJ
cord-298458-p7rvupjo	186	28	viral	viral	JJ
cord-298458-p7rvupjo	186	29	challenge	challenge	NN
cord-298458-p7rvupjo	186	30	in	in	IN
cord-298458-p7rvupjo	186	31	the	the	DT
cord-298458-p7rvupjo	186	32	absence	absence	NN
cord-298458-p7rvupjo	186	33	of	of	IN
cord-298458-p7rvupjo	186	34	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	186	35	(	(	-LRB-
cord-298458-p7rvupjo	186	36	28	28	CD
cord-298458-p7rvupjo	186	37	,	,	,
cord-298458-p7rvupjo	186	38	29	29	CD
cord-298458-p7rvupjo	186	39	)	)	-RRB-
cord-298458-p7rvupjo	186	40	.	.	.
cord-298458-p7rvupjo	187	1	Interestingly	interestingly	RB
cord-298458-p7rvupjo	187	2	,	,	,
cord-298458-p7rvupjo	187	3	the	the	DT
cord-298458-p7rvupjo	187	4	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	187	5	induced	induce	VBN
cord-298458-p7rvupjo	187	6	by	by	IN
cord-298458-p7rvupjo	187	7	RSV	RSV	NNP
cord-298458-p7rvupjo	187	8	-	-	HYPH
cord-298458-p7rvupjo	187	9	specific	specific	JJ
cord-298458-p7rvupjo	187	10	memory	memory	NN
cord-298458-p7rvupjo	187	11	CD8	CD8	NNP
cord-298458-p7rvupjo	187	12	T	T	NNP
cord-298458-p7rvupjo	187	13	cells	cell	NNS
cord-298458-p7rvupjo	187	14	occurred	occur	VBD
cord-298458-p7rvupjo	187	15	only	only	RB
cord-298458-p7rvupjo	187	16	in	in	IN
cord-298458-p7rvupjo	187	17	the	the	DT
cord-298458-p7rvupjo	187	18	context	context	NN
cord-298458-p7rvupjo	187	19	of	of	IN
cord-298458-p7rvupjo	187	20	an	an	DT
cord-298458-p7rvupjo	187	21	RSV	RSV	NNP
cord-298458-p7rvupjo	187	22	infection	infection	NN
cord-298458-p7rvupjo	187	23	,	,	,
cord-298458-p7rvupjo	187	24	as	as	IN
cord-298458-p7rvupjo	187	25	mice	mouse	NNS
cord-298458-p7rvupjo	187	26	challenged	challenge	VBD
cord-298458-p7rvupjo	187	27	with	with	IN
cord-298458-p7rvupjo	187	28	a	a	DT
cord-298458-p7rvupjo	187	29	recombinant	recombinant	JJ
cord-298458-p7rvupjo	187	30	IAV	IAV	NNP
cord-298458-p7rvupjo	187	31	strain	strain	NN
cord-298458-p7rvupjo	187	32	expressing	express	VBG
cord-298458-p7rvupjo	187	33	an	an	DT
cord-298458-p7rvupjo	187	34	RSV	RSV	NNP
cord-298458-p7rvupjo	187	35	-	-	HYPH
cord-298458-p7rvupjo	187	36	derived	derive	VBN
cord-298458-p7rvupjo	187	37	CD8	CD8	NNP
cord-298458-p7rvupjo	187	38	T	T	NNP
cord-298458-p7rvupjo	187	39	cell	cell	NN
cord-298458-p7rvupjo	187	40	epitope	epitope	NN
cord-298458-p7rvupjo	187	41	exhibited	exhibit	VBD
cord-298458-p7rvupjo	187	42	significantly	significantly	RB
cord-298458-p7rvupjo	187	43	reduced	reduce	VBN
cord-298458-p7rvupjo	187	44	morbidity	morbidity	NN
cord-298458-p7rvupjo	187	45	and	and	CC
cord-298458-p7rvupjo	187	46	were	be	VBD
cord-298458-p7rvupjo	187	47	protected	protect	VBN
cord-298458-p7rvupjo	187	48	from	from	IN
cord-298458-p7rvupjo	187	49	mortality	mortality	NN
cord-298458-p7rvupjo	187	50	(	(	-LRB-
cord-298458-p7rvupjo	187	51	30	30	CD
cord-298458-p7rvupjo	187	52	)	)	-RRB-
cord-298458-p7rvupjo	187	53	.	.	.
cord-298458-p7rvupjo	188	1	This	this	DT
cord-298458-p7rvupjo	188	2	result	result	NN
cord-298458-p7rvupjo	188	3	is	be	VBZ
cord-298458-p7rvupjo	188	4	consistent	consistent	JJ
cord-298458-p7rvupjo	188	5	with	with	IN
cord-298458-p7rvupjo	188	6	several	several	JJ
cord-298458-p7rvupjo	188	7	studies	study	NNS
cord-298458-p7rvupjo	188	8	that	that	WDT
cord-298458-p7rvupjo	188	9	demonstrate	demonstrate	VBP
cord-298458-p7rvupjo	188	10	CD8	CD8	NNP
cord-298458-p7rvupjo	188	11	T	T	NNP
cord-298458-p7rvupjo	188	12	cells	cell	NNS
cord-298458-p7rvupjo	188	13	enhance	enhance	VB
cord-298458-p7rvupjo	188	14	viral	viral	JJ
cord-298458-p7rvupjo	188	15	clearance	clearance	NN
cord-298458-p7rvupjo	188	16	while	while	IN
cord-298458-p7rvupjo	188	17	preventing	prevent	VBG
cord-298458-p7rvupjo	188	18	mortality	mortality	NN
cord-298458-p7rvupjo	188	19	following	follow	VBG
cord-298458-p7rvupjo	188	20	IAV	IAV	NNP
cord-298458-p7rvupjo	188	21	infection	infection	NN
cord-298458-p7rvupjo	188	22	(	(	-LRB-
cord-298458-p7rvupjo	188	23	25	25	CD
cord-298458-p7rvupjo	188	24	,	,	,
cord-298458-p7rvupjo	188	25	81	81	CD
cord-298458-p7rvupjo	188	26	,	,	,
cord-298458-p7rvupjo	188	27	85	85	CD
cord-298458-p7rvupjo	188	28	,	,	,
cord-298458-p7rvupjo	188	29	87	87	CD
cord-298458-p7rvupjo	188	30	,	,	,
cord-298458-p7rvupjo	188	31	117	117	CD
cord-298458-p7rvupjo	188	32	)	)	-RRB-
cord-298458-p7rvupjo	188	33	.	.	.
cord-298458-p7rvupjo	189	1	Together	together	RB
cord-298458-p7rvupjo	189	2	,	,	,
cord-298458-p7rvupjo	189	3	these	these	DT
cord-298458-p7rvupjo	189	4	studies	study	NNS
cord-298458-p7rvupjo	189	5	demonstrate	demonstrate	VBP
cord-298458-p7rvupjo	189	6	a	a	DT
cord-298458-p7rvupjo	189	7	clear	clear	JJ
cord-298458-p7rvupjo	189	8	role	role	NN
cord-298458-p7rvupjo	189	9	for	for	IN
cord-298458-p7rvupjo	189	10	CD8	CD8	NNP
cord-298458-p7rvupjo	189	11	T	T	NNP
cord-298458-p7rvupjo	189	12	cells	cell	NNS
cord-298458-p7rvupjo	189	13	in	in	IN
cord-298458-p7rvupjo	189	14	the	the	DT
cord-298458-p7rvupjo	189	15	development	development	NN
cord-298458-p7rvupjo	189	16	of	of	IN
cord-298458-p7rvupjo	189	17	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	189	18	following	follow	VBG
cord-298458-p7rvupjo	189	19	primary	primary	JJ
cord-298458-p7rvupjo	189	20	and	and	CC
cord-298458-p7rvupjo	189	21	secondary	secondary	JJ
cord-298458-p7rvupjo	189	22	infections	infection	NNS
cord-298458-p7rvupjo	189	23	with	with	IN
cord-298458-p7rvupjo	189	24	some	some	DT
cord-298458-p7rvupjo	189	25	respiratory	respiratory	JJ
cord-298458-p7rvupjo	189	26	virus	virus	NN
cord-298458-p7rvupjo	189	27	infections	infection	NNS
cord-298458-p7rvupjo	189	28	,	,	,
cord-298458-p7rvupjo	189	29	particularly	particularly	RB
cord-298458-p7rvupjo	189	30	RSV	RSV	NNP
cord-298458-p7rvupjo	189	31	.	.	.
cord-298458-p7rvupjo	190	1	Antiviral	antiviral	JJ
cord-298458-p7rvupjo	190	2	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	190	3	utilized	utilize	VBN
cord-298458-p7rvupjo	190	4	by	by	IN
cord-298458-p7rvupjo	190	5	CD8	CD8	NNP
cord-298458-p7rvupjo	190	6	T	T	NNP
cord-298458-p7rvupjo	190	7	cells	cell	NNS
cord-298458-p7rvupjo	190	8	to	to	TO
cord-298458-p7rvupjo	190	9	mediate	mediate	VB
cord-298458-p7rvupjo	190	10	viral	viral	JJ
cord-298458-p7rvupjo	190	11	clearance	clearance	NN
cord-298458-p7rvupjo	190	12	following	follow	VBG
cord-298458-p7rvupjo	190	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	190	14	virus	virus	NN
cord-298458-p7rvupjo	190	15	infection	infection	NN
cord-298458-p7rvupjo	190	16	also	also	RB
cord-298458-p7rvupjo	190	17	contribute	contribute	VBP
cord-298458-p7rvupjo	190	18	to	to	IN
cord-298458-p7rvupjo	190	19	the	the	DT
cord-298458-p7rvupjo	190	20	development	development	NN
cord-298458-p7rvupjo	190	21	of	of	IN
cord-298458-p7rvupjo	190	22	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	190	23	.	.	.
cord-298458-p7rvupjo	191	1	Removal	removal	NN
cord-298458-p7rvupjo	191	2	of	of	IN
cord-298458-p7rvupjo	191	3	the	the	DT
cord-298458-p7rvupjo	191	4	Fas/	Fas/	NNP
cord-298458-p7rvupjo	191	5	FasL	FasL	NNP
cord-298458-p7rvupjo	191	6	pathway	pathway	NN
cord-298458-p7rvupjo	191	7	in	in	IN
cord-298458-p7rvupjo	191	8	gld	gld	NNP
cord-298458-p7rvupjo	191	9	mice	mouse	NNS
cord-298458-p7rvupjo	191	10	resulted	result	VBD
cord-298458-p7rvupjo	191	11	in	in	IN
cord-298458-p7rvupjo	191	12	significant	significant	JJ
cord-298458-p7rvupjo	191	13	amelioration	amelioration	NN
cord-298458-p7rvupjo	191	14	of	of	IN
cord-298458-p7rvupjo	191	15	weight	weight	NN
cord-298458-p7rvupjo	191	16	loss	loss	NN
cord-298458-p7rvupjo	191	17	and	and	CC
cord-298458-p7rvupjo	191	18	symptom	symptom	NN
cord-298458-p7rvupjo	191	19	illness	illness	NN
cord-298458-p7rvupjo	191	20	scores	score	NNS
cord-298458-p7rvupjo	191	21	following	follow	VBG
cord-298458-p7rvupjo	191	22	RSV	RSV	NNP
cord-298458-p7rvupjo	191	23	infection	infection	NN
cord-298458-p7rvupjo	191	24	(	(	-LRB-
cord-298458-p7rvupjo	191	25	101	101	CD
cord-298458-p7rvupjo	191	26	)	)	-RRB-
cord-298458-p7rvupjo	191	27	.	.	.
cord-298458-p7rvupjo	192	1	Similarly	similarly	RB
cord-298458-p7rvupjo	192	2	,	,	,
cord-298458-p7rvupjo	192	3	RSV	RSV	NNP
cord-298458-p7rvupjo	192	4	-	-	HYPH
cord-298458-p7rvupjo	192	5	infected	infect	VBN
cord-298458-p7rvupjo	192	6	perforin	perforin	NN
cord-298458-p7rvupjo	192	7	-	-	HYPH
cord-298458-p7rvupjo	192	8	deficient	deficient	JJ
cord-298458-p7rvupjo	192	9	mice	mouse	NNS
cord-298458-p7rvupjo	192	10	exhibited	exhibit	VBD
cord-298458-p7rvupjo	192	11	prolonged	prolonged	JJ
cord-298458-p7rvupjo	192	12	weight	weight	NN
cord-298458-p7rvupjo	192	13	loss	loss	NN
cord-298458-p7rvupjo	192	14	and	and	CC
cord-298458-p7rvupjo	192	15	symptom	symptom	NN
cord-298458-p7rvupjo	192	16	illness	illness	NN
cord-298458-p7rvupjo	192	17	scores	score	NNS
cord-298458-p7rvupjo	192	18	compared	compare	VBN
cord-298458-p7rvupjo	192	19	to	to	IN
cord-298458-p7rvupjo	192	20	wild	wild	JJ
cord-298458-p7rvupjo	192	21	-	-	HYPH
cord-298458-p7rvupjo	192	22	type	type	NN
cord-298458-p7rvupjo	192	23	mice	mouse	NNS
cord-298458-p7rvupjo	192	24	(	(	-LRB-
cord-298458-p7rvupjo	192	25	100	100	CD
cord-298458-p7rvupjo	192	26	)	)	-RRB-
cord-298458-p7rvupjo	192	27	.	.	.
cord-298458-p7rvupjo	193	1	TNF	TNF	NNP
cord-298458-p7rvupjo	193	2	contributes	contribute	VBZ
cord-298458-p7rvupjo	193	3	substantially	substantially	RB
cord-298458-p7rvupjo	193	4	to	to	IN
cord-298458-p7rvupjo	193	5	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	193	6	,	,	,
cord-298458-p7rvupjo	193	7	as	as	IN
cord-298458-p7rvupjo	193	8	antibody	antibody	NN
cord-298458-p7rvupjo	193	9	-	-	HYPH
cord-298458-p7rvupjo	193	10	mediated	mediate	VBN
cord-298458-p7rvupjo	193	11	depletion	depletion	NN
cord-298458-p7rvupjo	193	12	of	of	IN
cord-298458-p7rvupjo	193	13	TNF	TNF	NNP
cord-298458-p7rvupjo	193	14	prior	prior	RB
cord-298458-p7rvupjo	193	15	to	to	IN
cord-298458-p7rvupjo	193	16	either	either	CC
cord-298458-p7rvupjo	193	17	RSV	RSV	NNP
cord-298458-p7rvupjo	193	18	or	or	CC
cord-298458-p7rvupjo	193	19	IAV	IAV	NNP
cord-298458-p7rvupjo	193	20	infection	infection	NN
cord-298458-p7rvupjo	193	21	significantly	significantly	RB
cord-298458-p7rvupjo	193	22	reduced	reduce	VBD
cord-298458-p7rvupjo	193	23	weight	weight	NN
cord-298458-p7rvupjo	193	24	loss	loss	NN
cord-298458-p7rvupjo	193	25	(	(	-LRB-
cord-298458-p7rvupjo	193	26	101	101	CD
cord-298458-p7rvupjo	193	27	,	,	,
cord-298458-p7rvupjo	193	28	102	102	CD
cord-298458-p7rvupjo	193	29	,	,	,
cord-298458-p7rvupjo	193	30	118	118	CD
cord-298458-p7rvupjo	193	31	)	)	-RRB-
cord-298458-p7rvupjo	193	32	.	.	.
cord-298458-p7rvupjo	194	1	Additionally	additionally	RB
cord-298458-p7rvupjo	194	2	,	,	,
cord-298458-p7rvupjo	194	3	mice	mouse	NNS
cord-298458-p7rvupjo	194	4	that	that	WDT
cord-298458-p7rvupjo	194	5	are	be	VBP
cord-298458-p7rvupjo	194	6	IFN	IFN	NNP
cord-298458-p7rvupjo	194	7	-	-	HYPH
cord-298458-p7rvupjo	194	8	γ	γ	NN
cord-298458-p7rvupjo	194	9	-	-	HYPH
cord-298458-p7rvupjo	194	10	deficient	deficient	JJ
cord-298458-p7rvupjo	194	11	,	,	,
cord-298458-p7rvupjo	194	12	depleted	deplete	VBN
cord-298458-p7rvupjo	194	13	of	of	IN
cord-298458-p7rvupjo	194	14	IFN	IFN	NNP
cord-298458-p7rvupjo	194	15	-	-	HYPH
cord-298458-p7rvupjo	194	16	γ	γ	NNP
cord-298458-p7rvupjo	194	17	,	,	,
cord-298458-p7rvupjo	194	18	or	or	CC
cord-298458-p7rvupjo	194	19	received	receive	VBD
cord-298458-p7rvupjo	194	20	an	an	DT
cord-298458-p7rvupjo	194	21	adoptive	adoptive	JJ
cord-298458-p7rvupjo	194	22	transfer	transfer	NN
cord-298458-p7rvupjo	194	23	of	of	IN
cord-298458-p7rvupjo	194	24	IFN	IFN	NNP
cord-298458-p7rvupjo	194	25	-	-	HYPH
cord-298458-p7rvupjo	194	26	γ	γ	NN
cord-298458-p7rvupjo	194	27	-	-	HYPH
cord-298458-p7rvupjo	194	28	deficient	deficient	JJ
cord-298458-p7rvupjo	194	29	CD8	CD8	NNP
cord-298458-p7rvupjo	194	30	T	T	NNP
cord-298458-p7rvupjo	194	31	cells	cell	NNS
cord-298458-p7rvupjo	194	32	prior	prior	RB
cord-298458-p7rvupjo	194	33	to	to	IN
cord-298458-p7rvupjo	194	34	RSV	RSV	NNP
cord-298458-p7rvupjo	194	35	infection	infection	NN
cord-298458-p7rvupjo	194	36	lost	lose	VBD
cord-298458-p7rvupjo	194	37	significantly	significantly	RB
cord-298458-p7rvupjo	194	38	less	less	JJR
cord-298458-p7rvupjo	194	39	weight	weight	NN
cord-298458-p7rvupjo	194	40	than	than	IN
cord-298458-p7rvupjo	194	41	controls	control	NNS
cord-298458-p7rvupjo	194	42	(	(	-LRB-
cord-298458-p7rvupjo	194	43	89	89	CD
cord-298458-p7rvupjo	194	44	)	)	-RRB-
cord-298458-p7rvupjo	194	45	.	.	.
cord-298458-p7rvupjo	195	1	CD8	CD8	NNP
cord-298458-p7rvupjo	195	2	T	T	NNP
cord-298458-p7rvupjo	195	3	cell	cell	NN
cord-298458-p7rvupjo	195	4	production	production	NN
cord-298458-p7rvupjo	195	5	of	of	IN
cord-298458-p7rvupjo	195	6	TNF	TNF	NNP
cord-298458-p7rvupjo	195	7	and	and	CC
cord-298458-p7rvupjo	195	8	IFN	IFN	NNP
cord-298458-p7rvupjo	195	9	-	-	HYPH
cord-298458-p7rvupjo	195	10	γ	γ	NNP
cord-298458-p7rvupjo	195	11	following	follow	VBG
cord-298458-p7rvupjo	195	12	PVM	PVM	NNP
cord-298458-p7rvupjo	195	13	infection	infection	NN
cord-298458-p7rvupjo	195	14	also	also	RB
cord-298458-p7rvupjo	195	15	induced	induce	VBD
cord-298458-p7rvupjo	195	16	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	195	17	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	195	18	by	by	IN
cord-298458-p7rvupjo	195	19	initiating	initiate	VBG
cord-298458-p7rvupjo	195	20	a	a	DT
cord-298458-p7rvupjo	195	21	cytokine	cytokine	NN
cord-298458-p7rvupjo	195	22	storm	storm	NN
cord-298458-p7rvupjo	195	23	(	(	-LRB-
cord-298458-p7rvupjo	195	24	119	119	CD
cord-298458-p7rvupjo	195	25	)	)	-RRB-
cord-298458-p7rvupjo	195	26	.	.	.
cord-298458-p7rvupjo	196	1	In	in	IN
cord-298458-p7rvupjo	196	2	addition	addition	NN
cord-298458-p7rvupjo	196	3	to	to	IN
cord-298458-p7rvupjo	196	4	causing	cause	VBG
cord-298458-p7rvupjo	196	5	disease	disease	NN
cord-298458-p7rvupjo	196	6	in	in	IN
cord-298458-p7rvupjo	196	7	acute	acute	JJ
cord-298458-p7rvupjo	196	8	respiratory	respiratory	JJ
cord-298458-p7rvupjo	196	9	infections	infection	NNS
cord-298458-p7rvupjo	196	10	,	,	,
cord-298458-p7rvupjo	196	11	IFN	IFN	NNP
cord-298458-p7rvupjo	196	12	-	-	HYPH
cord-298458-p7rvupjo	196	13	γ	γ	NNP
cord-298458-p7rvupjo	196	14	produced	produce	VBN
cord-298458-p7rvupjo	196	15	by	by	IN
cord-298458-p7rvupjo	196	16	memory	memory	NN
cord-298458-p7rvupjo	196	17	CD8	CD8	NNP
cord-298458-p7rvupjo	196	18	T	T	NNP
cord-298458-p7rvupjo	196	19	cells	cell	NNS
cord-298458-p7rvupjo	196	20	mediated	mediate	VBD
cord-298458-p7rvupjo	196	21	the	the	DT
cord-298458-p7rvupjo	196	22	severe	severe	JJ
cord-298458-p7rvupjo	196	23	and	and	CC
cord-298458-p7rvupjo	196	24	fatal	fatal	JJ
cord-298458-p7rvupjo	196	25	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	196	26	following	follow	VBG
cord-298458-p7rvupjo	196	27	RSV	RSV	NNP
cord-298458-p7rvupjo	196	28	infection	infection	NN
cord-298458-p7rvupjo	196	29	of	of	IN
cord-298458-p7rvupjo	196	30	DC	DC	NNP
cord-298458-p7rvupjo	196	31	-	-	HYPH
cord-298458-p7rvupjo	196	32	LM	LM	NNP
cord-298458-p7rvupjo	196	33	prime	prime	NN
cord-298458-p7rvupjo	196	34	-	-	HYPH
cord-298458-p7rvupjo	196	35	boosted	boost	VBN
cord-298458-p7rvupjo	196	36	mice	mouse	NNS
cord-298458-p7rvupjo	196	37	(	(	-LRB-
cord-298458-p7rvupjo	196	38	30	30	CD
cord-298458-p7rvupjo	196	39	)	)	-RRB-
cord-298458-p7rvupjo	196	40	.	.	.
cord-298458-p7rvupjo	197	1	The	the	DT
cord-298458-p7rvupjo	197	2	role	role	NN
cord-298458-p7rvupjo	197	3	of	of	IN
cord-298458-p7rvupjo	197	4	CD8	CD8	NNP
cord-298458-p7rvupjo	197	5	T	T	NNP
cord-298458-p7rvupjo	197	6	cells	cell	NNS
cord-298458-p7rvupjo	197	7	in	in	IN
cord-298458-p7rvupjo	197	8	the	the	DT
cord-298458-p7rvupjo	197	9	development	development	NN
cord-298458-p7rvupjo	197	10	of	of	IN
cord-298458-p7rvupjo	197	11	pathology	pathology	NN
cord-298458-p7rvupjo	197	12	following	follow	VBG
cord-298458-p7rvupjo	197	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	197	14	infections	infection	NNS
cord-298458-p7rvupjo	197	15	in	in	IN
cord-298458-p7rvupjo	197	16	humans	human	NNS
cord-298458-p7rvupjo	197	17	remains	remain	VBZ
cord-298458-p7rvupjo	197	18	unclear	unclear	JJ
cord-298458-p7rvupjo	197	19	.	.	.
cord-298458-p7rvupjo	198	1	The	the	DT
cord-298458-p7rvupjo	198	2	best	good	JJS
cord-298458-p7rvupjo	198	3	evidence	evidence	NN
cord-298458-p7rvupjo	198	4	supporting	support	VBG
cord-298458-p7rvupjo	198	5	a	a	DT
cord-298458-p7rvupjo	198	6	pathogenic	pathogenic	JJ
cord-298458-p7rvupjo	198	7	role	role	NN
cord-298458-p7rvupjo	198	8	for	for	IN
cord-298458-p7rvupjo	198	9	CD8	CD8	NNP
cord-298458-p7rvupjo	198	10	T	T	NNP
cord-298458-p7rvupjo	198	11	cells	cell	NNS
cord-298458-p7rvupjo	198	12	in	in	IN
cord-298458-p7rvupjo	198	13	humans	human	NNS
cord-298458-p7rvupjo	198	14	infected	infect	VBN
cord-298458-p7rvupjo	198	15	with	with	IN
cord-298458-p7rvupjo	198	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	198	17	viruses	virus	NNS
cord-298458-p7rvupjo	198	18	comes	come	VBZ
cord-298458-p7rvupjo	198	19	from	from	IN
cord-298458-p7rvupjo	198	20	a	a	DT
cord-298458-p7rvupjo	198	21	study	study	NN
cord-298458-p7rvupjo	198	22	evaluating	evaluate	VBG
cord-298458-p7rvupjo	198	23	an	an	DT
cord-298458-p7rvupjo	198	24	RSV	RSV	NNP
cord-298458-p7rvupjo	198	25	-	-	HYPH
cord-298458-p7rvupjo	198	26	infected	infect	VBN
cord-298458-p7rvupjo	198	27	severe	severe	RB
cord-298458-p7rvupjo	198	28	-	-	HYPH
cord-298458-p7rvupjo	198	29	combined	combine	VBN
cord-298458-p7rvupjo	198	30	immunodeficiency	immunodeficiency	NN
cord-298458-p7rvupjo	198	31	patient	patient	NN
cord-298458-p7rvupjo	198	32	after	after	IN
cord-298458-p7rvupjo	198	33	bone	bone	NN
cord-298458-p7rvupjo	198	34	marrow	marrow	NN
cord-298458-p7rvupjo	198	35	transplantation	transplantation	NN
cord-298458-p7rvupjo	198	36	(	(	-LRB-
cord-298458-p7rvupjo	198	37	92	92	CD
cord-298458-p7rvupjo	198	38	)	)	-RRB-
cord-298458-p7rvupjo	198	39	.	.	.
cord-298458-p7rvupjo	199	1	The	the	DT
cord-298458-p7rvupjo	199	2	patient	patient	NN
cord-298458-p7rvupjo	199	3	exhibited	exhibit	VBD
cord-298458-p7rvupjo	199	4	increased	increase	VBN
cord-298458-p7rvupjo	199	5	CD8	CD8	NNP
cord-298458-p7rvupjo	199	6	T	T	NNP
cord-298458-p7rvupjo	199	7	cell	cell	NN
cord-298458-p7rvupjo	199	8	counts	count	VBZ
cord-298458-p7rvupjo	199	9	following	follow	VBG
cord-298458-p7rvupjo	199	10	bone	bone	NN
cord-298458-p7rvupjo	199	11	marrow	marrow	NN
cord-298458-p7rvupjo	199	12	transplant	transplant	NN
cord-298458-p7rvupjo	199	13	,	,	,
cord-298458-p7rvupjo	199	14	which	which	WDT
cord-298458-p7rvupjo	199	15	corresponded	correspond	VBD
cord-298458-p7rvupjo	199	16	to	to	IN
cord-298458-p7rvupjo	199	17	a	a	DT
cord-298458-p7rvupjo	199	18	sharp	sharp	JJ
cord-298458-p7rvupjo	199	19	reduction	reduction	NN
cord-298458-p7rvupjo	199	20	in	in	IN
cord-298458-p7rvupjo	199	21	RSV	RSV	NNP
cord-298458-p7rvupjo	199	22	nasal	nasal	NN
cord-298458-p7rvupjo	199	23	titers	titer	NNS
cord-298458-p7rvupjo	199	24	.	.	.
cord-298458-p7rvupjo	200	1	However	however	RB
cord-298458-p7rvupjo	200	2	,	,	,
cord-298458-p7rvupjo	200	3	the	the	DT
cord-298458-p7rvupjo	200	4	appearance	appearance	NN
cord-298458-p7rvupjo	200	5	of	of	IN
cord-298458-p7rvupjo	200	6	CD8	CD8	NNP
cord-298458-p7rvupjo	200	7	T	T	NNP
cord-298458-p7rvupjo	200	8	cells	cell	NNS
cord-298458-p7rvupjo	200	9	also	also	RB
cord-298458-p7rvupjo	200	10	correlated	correlate	VBD
cord-298458-p7rvupjo	200	11	with	with	IN
cord-298458-p7rvupjo	200	12	a	a	DT
cord-298458-p7rvupjo	200	13	marked	marked	JJ
cord-298458-p7rvupjo	200	14	increase	increase	NN
cord-298458-p7rvupjo	200	15	in	in	IN
cord-298458-p7rvupjo	200	16	respiratory	respiratory	JJ
cord-298458-p7rvupjo	200	17	rate	rate	NN
cord-298458-p7rvupjo	200	18	indicative	indicative	JJ
cord-298458-p7rvupjo	200	19	of	of	IN
cord-298458-p7rvupjo	200	20	reduced	reduce	VBN
cord-298458-p7rvupjo	200	21	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	200	22	function	function	NN
cord-298458-p7rvupjo	200	23	.	.	.
cord-298458-p7rvupjo	201	1	Also	also	RB
cord-298458-p7rvupjo	201	2	supporting	support	VBG
cord-298458-p7rvupjo	201	3	a	a	DT
cord-298458-p7rvupjo	201	4	pathogenic	pathogenic	JJ
cord-298458-p7rvupjo	201	5	role	role	NN
cord-298458-p7rvupjo	201	6	of	of	IN
cord-298458-p7rvupjo	201	7	CD8	CD8	NNP
cord-298458-p7rvupjo	201	8	T	T	NNP
cord-298458-p7rvupjo	201	9	cells	cell	NNS
cord-298458-p7rvupjo	201	10	is	be	VBZ
cord-298458-p7rvupjo	201	11	the	the	DT
cord-298458-p7rvupjo	201	12	finding	finding	NN
cord-298458-p7rvupjo	201	13	that	that	IN
cord-298458-p7rvupjo	201	14	children	child	NNS
cord-298458-p7rvupjo	201	15	requiring	require	VBG
cord-298458-p7rvupjo	201	16	mechanical	mechanical	JJ
cord-298458-p7rvupjo	201	17	ventilation	ventilation	NN
cord-298458-p7rvupjo	201	18	due	due	IN
cord-298458-p7rvupjo	201	19	to	to	IN
cord-298458-p7rvupjo	201	20	severe	severe	JJ
cord-298458-p7rvupjo	201	21	RSV	RSV	NNP
cord-298458-p7rvupjo	201	22	infection	infection	NN
cord-298458-p7rvupjo	201	23	expressed	express	VBD
cord-298458-p7rvupjo	201	24	significantly	significantly	RB
cord-298458-p7rvupjo	201	25	increased	increase	VBN
cord-298458-p7rvupjo	201	26	levels	level	NNS
cord-298458-p7rvupjo	201	27	of	of	IN
cord-298458-p7rvupjo	201	28	activated	activate	VBN
cord-298458-p7rvupjo	201	29	granzymes	granzyme	NNS
cord-298458-p7rvupjo	201	30	and	and	CC
cord-298458-p7rvupjo	201	31	more	more	JJR
cord-298458-p7rvupjo	201	32	CD8	CD8	NNP
cord-298458-p7rvupjo	201	33	T	T	NNP
cord-298458-p7rvupjo	201	34	cells	cell	NNS
cord-298458-p7rvupjo	201	35	producing	produce	VBG
cord-298458-p7rvupjo	201	36	granzyme	granzyme	NNS
cord-298458-p7rvupjo	201	37	B	B	NNP
cord-298458-p7rvupjo	201	38	compared	compare	VBN
cord-298458-p7rvupjo	201	39	to	to	IN
cord-298458-p7rvupjo	201	40	healthy	healthy	JJ
cord-298458-p7rvupjo	201	41	controls	control	NNS
cord-298458-p7rvupjo	201	42	(	(	-LRB-
cord-298458-p7rvupjo	201	43	120	120	CD
cord-298458-p7rvupjo	201	44	)	)	-RRB-
cord-298458-p7rvupjo	201	45	.	.	.
cord-298458-p7rvupjo	202	1	In	in	IN
cord-298458-p7rvupjo	202	2	contrast	contrast	NN
cord-298458-p7rvupjo	202	3	,	,	,
cord-298458-p7rvupjo	202	4	a	a	DT
cord-298458-p7rvupjo	202	5	study	study	NN
cord-298458-p7rvupjo	202	6	of	of	IN
cord-298458-p7rvupjo	202	7	infants	infant	NNS
cord-298458-p7rvupjo	202	8	following	follow	VBG
cord-298458-p7rvupjo	202	9	either	either	CC
cord-298458-p7rvupjo	202	10	fatal	fatal	JJ
cord-298458-p7rvupjo	202	11	IAV	IAV	NNP
cord-298458-p7rvupjo	202	12	or	or	CC
cord-298458-p7rvupjo	202	13	RSV	RSV	NNP
cord-298458-p7rvupjo	202	14	infections	infection	NNS
cord-298458-p7rvupjo	202	15	revealed	reveal	VBD
cord-298458-p7rvupjo	202	16	a	a	DT
cord-298458-p7rvupjo	202	17	near	near	JJ
cord-298458-p7rvupjo	202	18	absence	absence	NN
cord-298458-p7rvupjo	202	19	of	of	IN
cord-298458-p7rvupjo	202	20	CD8	CD8	NNP
cord-298458-p7rvupjo	202	21	T	T	NNP
cord-298458-p7rvupjo	202	22	cells	cell	NNS
cord-298458-p7rvupjo	202	23	from	from	IN
cord-298458-p7rvupjo	202	24	affected	affected	JJ
cord-298458-p7rvupjo	202	25	lung	lung	NN
cord-298458-p7rvupjo	202	26	regions	region	NNS
cord-298458-p7rvupjo	202	27	by	by	IN
cord-298458-p7rvupjo	202	28	immunohistochemical	immunohistochemical	JJ
cord-298458-p7rvupjo	202	29	staining	staining	NN
cord-298458-p7rvupjo	202	30	(	(	-LRB-
cord-298458-p7rvupjo	202	31	121	121	CD
cord-298458-p7rvupjo	202	32	,	,	,
cord-298458-p7rvupjo	202	33	122	122	CD
cord-298458-p7rvupjo	202	34	)	)	-RRB-
cord-298458-p7rvupjo	202	35	.	.	.
cord-298458-p7rvupjo	203	1	Similarly	similarly	RB
cord-298458-p7rvupjo	203	2	,	,	,
cord-298458-p7rvupjo	203	3	infants	infant	NNS
cord-298458-p7rvupjo	203	4	with	with	IN
cord-298458-p7rvupjo	203	5	severe	severe	JJ
cord-298458-p7rvupjo	203	6	RSV	RSV	NNP
cord-298458-p7rvupjo	203	7	infection	infection	NN
cord-298458-p7rvupjo	203	8	exhibited	exhibit	VBD
cord-298458-p7rvupjo	203	9	an	an	DT
cord-298458-p7rvupjo	203	10	underexpression	underexpression	NN
cord-298458-p7rvupjo	203	11	of	of	IN
cord-298458-p7rvupjo	203	12	genes	gene	NNS
cord-298458-p7rvupjo	203	13	related	relate	VBN
cord-298458-p7rvupjo	203	14	to	to	IN
cord-298458-p7rvupjo	203	15	CD8	CD8	NNP
cord-298458-p7rvupjo	203	16	T	T	NNP
cord-298458-p7rvupjo	203	17	cells	cell	NNS
cord-298458-p7rvupjo	203	18	in	in	IN
cord-298458-p7rvupjo	203	19	the	the	DT
cord-298458-p7rvupjo	203	20	peripheral	peripheral	JJ
cord-298458-p7rvupjo	203	21	blood	blood	NN
cord-298458-p7rvupjo	203	22	(	(	-LRB-
cord-298458-p7rvupjo	203	23	123	123	CD
cord-298458-p7rvupjo	203	24	)	)	-RRB-
cord-298458-p7rvupjo	203	25	.	.	.
cord-298458-p7rvupjo	204	1	In	in	IN
cord-298458-p7rvupjo	204	2	support	support	NN
cord-298458-p7rvupjo	204	3	of	of	IN
cord-298458-p7rvupjo	204	4	a	a	DT
cord-298458-p7rvupjo	204	5	protective	protective	JJ
cord-298458-p7rvupjo	204	6	,	,	,
cord-298458-p7rvupjo	204	7	rather	rather	RB
cord-298458-p7rvupjo	204	8	than	than	IN
cord-298458-p7rvupjo	204	9	pathogenic	pathogenic	JJ
cord-298458-p7rvupjo	204	10	,	,	,
cord-298458-p7rvupjo	204	11	role	role	NN
cord-298458-p7rvupjo	204	12	of	of	IN
cord-298458-p7rvupjo	204	13	CD8	CD8	NNP
cord-298458-p7rvupjo	204	14	T	T	NNP
cord-298458-p7rvupjo	204	15	cells	cell	NNS
cord-298458-p7rvupjo	204	16	,	,	,
cord-298458-p7rvupjo	204	17	correlations	correlation	NNS
cord-298458-p7rvupjo	204	18	have	have	VBP
cord-298458-p7rvupjo	204	19	been	be	VBN
cord-298458-p7rvupjo	204	20	identified	identify	VBN
cord-298458-p7rvupjo	204	21	between	between	IN
cord-298458-p7rvupjo	204	22	increased	increase	VBN
cord-298458-p7rvupjo	204	23	CD8	CD8	NNP
cord-298458-p7rvupjo	204	24	T	T	NNP
cord-298458-p7rvupjo	204	25	cell	cell	NN
cord-298458-p7rvupjo	204	26	cytolytic	cytolytic	NN
cord-298458-p7rvupjo	204	27	activity	activity	NN
cord-298458-p7rvupjo	204	28	and	and	CC
cord-298458-p7rvupjo	204	29	cytokine	cytokine	NN
cord-298458-p7rvupjo	204	30	production	production	NN
cord-298458-p7rvupjo	204	31	with	with	IN
cord-298458-p7rvupjo	204	32	reduced	reduce	VBN
cord-298458-p7rvupjo	204	33	symptom	symptom	NN
cord-298458-p7rvupjo	204	34	score	score	NN
cord-298458-p7rvupjo	204	35	,	,	,
cord-298458-p7rvupjo	204	36	faster	fast	JJR
cord-298458-p7rvupjo	204	37	recovery	recovery	NN
cord-298458-p7rvupjo	204	38	,	,	,
cord-298458-p7rvupjo	204	39	and	and	CC
cord-298458-p7rvupjo	204	40	fewer	few	JJR
cord-298458-p7rvupjo	204	41	fatalities	fatality	NNS
cord-298458-p7rvupjo	204	42	following	follow	VBG
cord-298458-p7rvupjo	204	43	H1N1	H1N1	NNP
cord-298458-p7rvupjo	204	44	or	or	CC
cord-298458-p7rvupjo	204	45	H7N9	H7N9	NNP
cord-298458-p7rvupjo	204	46	IAV	IAV	NNP
cord-298458-p7rvupjo	204	47	infections	infection	NNS
cord-298458-p7rvupjo	204	48	(	(	-LRB-
cord-298458-p7rvupjo	204	49	93	93	CD
cord-298458-p7rvupjo	204	50	,	,	,
cord-298458-p7rvupjo	204	51	94	94	CD
cord-298458-p7rvupjo	204	52	)	)	-RRB-
cord-298458-p7rvupjo	204	53	.	.	.
cord-298458-p7rvupjo	205	1	Therefore	therefore	RB
cord-298458-p7rvupjo	205	2	,	,	,
cord-298458-p7rvupjo	205	3	whether	whether	IN
cord-298458-p7rvupjo	205	4	CD8	CD8	NNP
cord-298458-p7rvupjo	205	5	T	T	NNP
cord-298458-p7rvupjo	205	6	cells	cell	NNS
cord-298458-p7rvupjo	205	7	play	play	VBP
cord-298458-p7rvupjo	205	8	a	a	DT
cord-298458-p7rvupjo	205	9	primary	primary	JJ
cord-298458-p7rvupjo	205	10	role	role	NN
cord-298458-p7rvupjo	205	11	in	in	IN
cord-298458-p7rvupjo	205	12	mediating	mediate	VBG
cord-298458-p7rvupjo	205	13	pathology	pathology	NN
cord-298458-p7rvupjo	205	14	versus	versus	IN
cord-298458-p7rvupjo	205	15	protection	protection	NN
cord-298458-p7rvupjo	205	16	following	follow	VBG
cord-298458-p7rvupjo	205	17	human	human	JJ
cord-298458-p7rvupjo	205	18	respiratory	respiratory	JJ
cord-298458-p7rvupjo	205	19	virus	virus	NN
cord-298458-p7rvupjo	205	20	infection	infection	NN
cord-298458-p7rvupjo	205	21	remains	remain	VBZ
cord-298458-p7rvupjo	205	22	controversial	controversial	JJ
cord-298458-p7rvupjo	205	23	and	and	CC
cord-298458-p7rvupjo	205	24	is	be	VBZ
cord-298458-p7rvupjo	205	25	an	an	DT
cord-298458-p7rvupjo	205	26	important	important	JJ
cord-298458-p7rvupjo	205	27	topic	topic	NN
cord-298458-p7rvupjo	205	28	of	of	IN
cord-298458-p7rvupjo	205	29	future	future	JJ
cord-298458-p7rvupjo	205	30	investigation	investigation	NN
cord-298458-p7rvupjo	205	31	.	.	.
cord-298458-p7rvupjo	206	1	Given	give	VBN
cord-298458-p7rvupjo	206	2	the	the	DT
cord-298458-p7rvupjo	206	3	potential	potential	NN
cord-298458-p7rvupjo	206	4	of	of	IN
cord-298458-p7rvupjo	206	5	CD8	CD8	NNP
cord-298458-p7rvupjo	206	6	T	T	NNP
cord-298458-p7rvupjo	206	7	cell	cell	NN
cord-298458-p7rvupjo	206	8	effector	effector	NN
cord-298458-p7rvupjo	206	9	functions	function	NNS
cord-298458-p7rvupjo	206	10	to	to	TO
cord-298458-p7rvupjo	206	11	cause	cause	VB
cord-298458-p7rvupjo	206	12	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	206	13	following	follow	VBG
cord-298458-p7rvupjo	206	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	206	15	virus	virus	NN
cord-298458-p7rvupjo	206	16	infection	infection	NN
cord-298458-p7rvupjo	206	17	,	,	,
cord-298458-p7rvupjo	206	18	the	the	DT
cord-298458-p7rvupjo	206	19	immune	immune	JJ
cord-298458-p7rvupjo	206	20	system	system	NN
cord-298458-p7rvupjo	206	21	has	have	VBZ
cord-298458-p7rvupjo	206	22	evolved	evolve	VBN
cord-298458-p7rvupjo	206	23	critical	critical	JJ
cord-298458-p7rvupjo	206	24	regulatory	regulatory	JJ
cord-298458-p7rvupjo	206	25	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	206	26	to	to	TO
cord-298458-p7rvupjo	206	27	prevent	prevent	VB
cord-298458-p7rvupjo	206	28	prolonged	prolong	VBN
cord-298458-p7rvupjo	206	29	CD8	CD8	NNP
cord-298458-p7rvupjo	206	30	T	T	NNP
cord-298458-p7rvupjo	206	31	cell	cell	NN
cord-298458-p7rvupjo	206	32	effector	effector	NN
cord-298458-p7rvupjo	206	33	activity	activity	NN
cord-298458-p7rvupjo	206	34	following	follow	VBG
cord-298458-p7rvupjo	206	35	viral	viral	JJ
cord-298458-p7rvupjo	206	36	clearance	clearance	NN
cord-298458-p7rvupjo	206	37	.	.	.
cord-298458-p7rvupjo	207	1	CD8	CD8	NNP
cord-298458-p7rvupjo	207	2	T	T	NNP
cord-298458-p7rvupjo	207	3	cell	cell	NN
cord-298458-p7rvupjo	207	4	effector	effector	NN
cord-298458-p7rvupjo	207	5	functions	function	NNS
cord-298458-p7rvupjo	207	6	,	,	,
cord-298458-p7rvupjo	207	7	including	include	VBG
cord-298458-p7rvupjo	207	8	production	production	NN
cord-298458-p7rvupjo	207	9	of	of	IN
cord-298458-p7rvupjo	207	10	IFN	IFN	NNP
cord-298458-p7rvupjo	207	11	-	-	HYPH
cord-298458-p7rvupjo	207	12	γ	γ	NNP
cord-298458-p7rvupjo	207	13	and	and	CC
cord-298458-p7rvupjo	207	14	TNF	TNF	NNP
cord-298458-p7rvupjo	207	15	,	,	,
cord-298458-p7rvupjo	207	16	are	be	VBP
cord-298458-p7rvupjo	207	17	suppressed	suppress	VBN
cord-298458-p7rvupjo	207	18	in	in	IN
cord-298458-p7rvupjo	207	19	the	the	DT
cord-298458-p7rvupjo	207	20	lung	lung	NN
cord-298458-p7rvupjo	207	21	following	follow	VBG
cord-298458-p7rvupjo	207	22	the	the	DT
cord-298458-p7rvupjo	207	23	resolution	resolution	NN
cord-298458-p7rvupjo	207	24	of	of	IN
cord-298458-p7rvupjo	207	25	IAV	IAV	NNP
cord-298458-p7rvupjo	207	26	and	and	CC
cord-298458-p7rvupjo	207	27	RSV	RSV	NNP
cord-298458-p7rvupjo	207	28	infections	infection	NNS
cord-298458-p7rvupjo	207	29	(	(	-LRB-
cord-298458-p7rvupjo	207	30	124	124	CD
cord-298458-p7rvupjo	207	31	)	)	-RRB-
cord-298458-p7rvupjo	207	32	(	(	-LRB-
cord-298458-p7rvupjo	207	33	125	125	CD
cord-298458-p7rvupjo	207	34	)	)	-RRB-
cord-298458-p7rvupjo	207	35	(	(	-LRB-
cord-298458-p7rvupjo	207	36	126	126	CD
cord-298458-p7rvupjo	207	37	)	)	-RRB-
cord-298458-p7rvupjo	207	38	(	(	-LRB-
cord-298458-p7rvupjo	207	39	127	127	CD
cord-298458-p7rvupjo	207	40	)	)	-RRB-
cord-298458-p7rvupjo	207	41	.	.	.
cord-298458-p7rvupjo	208	1	One	one	CD
cord-298458-p7rvupjo	208	2	of	of	IN
cord-298458-p7rvupjo	208	3	the	the	DT
cord-298458-p7rvupjo	208	4	primary	primary	JJ
cord-298458-p7rvupjo	208	5	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	208	6	utilized	utilize	VBN
cord-298458-p7rvupjo	208	7	to	to	TO
cord-298458-p7rvupjo	208	8	limit	limit	VB
cord-298458-p7rvupjo	208	9	the	the	DT
cord-298458-p7rvupjo	208	10	CD8	CD8	NNP
cord-298458-p7rvupjo	208	11	T	T	NNP
cord-298458-p7rvupjo	208	12	cell	cell	NN
cord-298458-p7rvupjo	208	13	response	response	NN
cord-298458-p7rvupjo	208	14	is	be	VBZ
cord-298458-p7rvupjo	208	15	through	through	IN
cord-298458-p7rvupjo	208	16	suppression	suppression	NN
cord-298458-p7rvupjo	208	17	by	by	IN
cord-298458-p7rvupjo	208	18	regulatory	regulatory	JJ
cord-298458-p7rvupjo	208	19	CD4	CD4	NNP
cord-298458-p7rvupjo	208	20	T	T	NNP
cord-298458-p7rvupjo	208	21	cells	cell	NNS
cord-298458-p7rvupjo	208	22	(	(	-LRB-
cord-298458-p7rvupjo	208	23	Tregs	Tregs	NNP
cord-298458-p7rvupjo	208	24	)	)	-RRB-
cord-298458-p7rvupjo	208	25	.	.	.
cord-298458-p7rvupjo	209	1	Tregs	Tregs	NNP
cord-298458-p7rvupjo	209	2	accumulate	accumulate	VBP
cord-298458-p7rvupjo	209	3	in	in	IN
cord-298458-p7rvupjo	209	4	the	the	DT
cord-298458-p7rvupjo	209	5	lungs	lung	NNS
cord-298458-p7rvupjo	209	6	following	follow	VBG
cord-298458-p7rvupjo	209	7	either	either	CC
cord-298458-p7rvupjo	209	8	RSV	RSV	NNP
cord-298458-p7rvupjo	209	9	or	or	CC
cord-298458-p7rvupjo	209	10	IAV	IAV	NNP
cord-298458-p7rvupjo	209	11	infection	infection	NN
cord-298458-p7rvupjo	209	12	peaking	peak	VBG
cord-298458-p7rvupjo	209	13	at	at	IN
cord-298458-p7rvupjo	209	14	approximately	approximately	RB
cord-298458-p7rvupjo	209	15	day	day	NN
cord-298458-p7rvupjo	209	16	6	6	CD
cord-298458-p7rvupjo	209	17	post	post	NN
cord-298458-p7rvupjo	209	18	-	-	NN
cord-298458-p7rvupjo	209	19	infection	infection	NN
cord-298458-p7rvupjo	209	20	,	,	,
cord-298458-p7rvupjo	209	21	prior	prior	RB
cord-298458-p7rvupjo	209	22	to	to	IN
cord-298458-p7rvupjo	209	23	the	the	DT
cord-298458-p7rvupjo	209	24	peak	peak	NN
cord-298458-p7rvupjo	209	25	of	of	IN
cord-298458-p7rvupjo	209	26	the	the	DT
cord-298458-p7rvupjo	209	27	CD8	CD8	NNP
cord-298458-p7rvupjo	209	28	T	T	NNP
cord-298458-p7rvupjo	209	29	cell	cell	NN
cord-298458-p7rvupjo	209	30	response	response	NN
cord-298458-p7rvupjo	209	31	(	(	-LRB-
cord-298458-p7rvupjo	209	32	36	36	CD
cord-298458-p7rvupjo	209	33	,	,	,
cord-298458-p7rvupjo	209	34	(	(	-LRB-
cord-298458-p7rvupjo	209	35	128	128	CD
cord-298458-p7rvupjo	209	36	)	)	-RRB-
cord-298458-p7rvupjo	209	37	(	(	-LRB-
cord-298458-p7rvupjo	209	38	129	129	CD
cord-298458-p7rvupjo	209	39	)	)	-RRB-
cord-298458-p7rvupjo	209	40	(	(	-LRB-
cord-298458-p7rvupjo	209	41	130	130	CD
cord-298458-p7rvupjo	209	42	)	)	-RRB-
cord-298458-p7rvupjo	209	43	.	.	.
cord-298458-p7rvupjo	210	1	Antibody	antibody	NN
cord-298458-p7rvupjo	210	2	-	-	HYPH
cord-298458-p7rvupjo	210	3	mediated	mediate	VBN
cord-298458-p7rvupjo	210	4	depletion	depletion	NN
cord-298458-p7rvupjo	210	5	of	of	IN
cord-298458-p7rvupjo	210	6	CD25	CD25	NNP
cord-298458-p7rvupjo	210	7	+	+	CC
cord-298458-p7rvupjo	210	8	Tregs	Tregs	NNP
cord-298458-p7rvupjo	211	1	prior	prior	RB
cord-298458-p7rvupjo	211	2	to	to	IN
cord-298458-p7rvupjo	211	3	RSV	RSV	NNP
cord-298458-p7rvupjo	211	4	infection	infection	NN
cord-298458-p7rvupjo	211	5	resulted	result	VBD
cord-298458-p7rvupjo	211	6	in	in	IN
cord-298458-p7rvupjo	211	7	exacerbated	exacerbated	JJ
cord-298458-p7rvupjo	211	8	weight	weight	NN
cord-298458-p7rvupjo	211	9	loss	loss	NN
cord-298458-p7rvupjo	211	10	,	,	,
cord-298458-p7rvupjo	211	11	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	211	12	dysfunction	dysfunction	NN
cord-298458-p7rvupjo	211	13	,	,	,
cord-298458-p7rvupjo	211	14	and	and	CC
cord-298458-p7rvupjo	211	15	lung	lung	NN
cord-298458-p7rvupjo	211	16	inflammation	inflammation	NN
cord-298458-p7rvupjo	211	17	(	(	-LRB-
cord-298458-p7rvupjo	211	18	128	128	CD
cord-298458-p7rvupjo	211	19	)	)	-RRB-
cord-298458-p7rvupjo	211	20	.	.	.
cord-298458-p7rvupjo	212	1	This	this	DT
cord-298458-p7rvupjo	212	2	enhanced	enhance	VBN
cord-298458-p7rvupjo	212	3	illness	illness	NN
cord-298458-p7rvupjo	212	4	corresponded	correspond	VBD
cord-298458-p7rvupjo	212	5	to	to	IN
cord-298458-p7rvupjo	212	6	an	an	DT
cord-298458-p7rvupjo	212	7	increased	increase	VBN
cord-298458-p7rvupjo	212	8	frequency	frequency	NN
cord-298458-p7rvupjo	212	9	of	of	IN
cord-298458-p7rvupjo	212	10	RSV	rsv	NN
cord-298458-p7rvupjo	212	11	-	-	HYPH
cord-298458-p7rvupjo	212	12	specific	specific	JJ
cord-298458-p7rvupjo	212	13	CD8	CD8	NNP
cord-298458-p7rvupjo	212	14	T	T	NNP
cord-298458-p7rvupjo	212	15	cells	cell	NNS
cord-298458-p7rvupjo	212	16	and	and	CC
cord-298458-p7rvupjo	212	17	elevated	elevated	JJ
cord-298458-p7rvupjo	212	18	levels	level	NNS
cord-298458-p7rvupjo	212	19	of	of	IN
cord-298458-p7rvupjo	212	20	IFN	IFN	NNP
cord-298458-p7rvupjo	212	21	-	-	HYPH
cord-298458-p7rvupjo	212	22	γ	γ	NNP
cord-298458-p7rvupjo	212	23	and	and	CC
cord-298458-p7rvupjo	212	24	TNF	TNF	NNP
cord-298458-p7rvupjo	212	25	protein	protein	NN
cord-298458-p7rvupjo	212	26	in	in	IN
cord-298458-p7rvupjo	212	27	the	the	DT
cord-298458-p7rvupjo	212	28	lung	lung	NN
cord-298458-p7rvupjo	212	29	(	(	-LRB-
cord-298458-p7rvupjo	212	30	36	36	CD
cord-298458-p7rvupjo	212	31	,	,	,
cord-298458-p7rvupjo	212	32	128	128	CD
cord-298458-p7rvupjo	212	33	)	)	-RRB-
cord-298458-p7rvupjo	212	34	.	.	.
cord-298458-p7rvupjo	213	1	Consistent	consistent	JJ
cord-298458-p7rvupjo	213	2	with	with	IN
cord-298458-p7rvupjo	213	3	the	the	DT
cord-298458-p7rvupjo	213	4	Treg	Treg	NNP
cord-298458-p7rvupjo	213	5	depletion	depletion	NN
cord-298458-p7rvupjo	213	6	studies	study	NNS
cord-298458-p7rvupjo	213	7	,	,	,
cord-298458-p7rvupjo	213	8	increasing	increase	VBG
cord-298458-p7rvupjo	213	9	RSV	rsv	NN
cord-298458-p7rvupjo	213	10	-	-	HYPH
cord-298458-p7rvupjo	213	11	specific	specific	JJ
cord-298458-p7rvupjo	213	12	Tregs	Tregs	NNP
cord-298458-p7rvupjo	213	13	prior	prior	RB
cord-298458-p7rvupjo	213	14	to	to	IN
cord-298458-p7rvupjo	213	15	RSV	RSV	NNP
cord-298458-p7rvupjo	213	16	infection	infection	NN
cord-298458-p7rvupjo	213	17	using	use	VBG
cord-298458-p7rvupjo	213	18	RSV	RSV	NNP
cord-298458-p7rvupjo	213	19	peptide	peptide	NN
cord-298458-p7rvupjo	213	20	-	-	HYPH
cord-298458-p7rvupjo	213	21	immunization	immunization	NN
cord-298458-p7rvupjo	213	22	resulted	result	VBD
cord-298458-p7rvupjo	213	23	in	in	IN
cord-298458-p7rvupjo	213	24	an	an	DT
cord-298458-p7rvupjo	213	25	amelioration	amelioration	NN
cord-298458-p7rvupjo	213	26	of	of	IN
cord-298458-p7rvupjo	213	27	weight	weight	NN
cord-298458-p7rvupjo	213	28	loss	loss	NN
cord-298458-p7rvupjo	213	29	and	and	CC
cord-298458-p7rvupjo	213	30	a	a	DT
cord-298458-p7rvupjo	213	31	reduction	reduction	NN
cord-298458-p7rvupjo	213	32	in	in	IN
cord-298458-p7rvupjo	213	33	CD8	CD8	NNP
cord-298458-p7rvupjo	213	34	T	T	NNP
cord-298458-p7rvupjo	213	35	cell	cell	NN
cord-298458-p7rvupjo	213	36	numbers	number	NNS
cord-298458-p7rvupjo	213	37	in	in	IN
cord-298458-p7rvupjo	213	38	the	the	DT
cord-298458-p7rvupjo	213	39	blood	blood	NN
cord-298458-p7rvupjo	213	40	and	and	CC
cord-298458-p7rvupjo	213	41	spleen	spleen	NNS
cord-298458-p7rvupjo	213	42	,	,	,
cord-298458-p7rvupjo	213	43	but	but	CC
cord-298458-p7rvupjo	213	44	not	not	RB
cord-298458-p7rvupjo	213	45	the	the	DT
cord-298458-p7rvupjo	213	46	lung	lung	NN
cord-298458-p7rvupjo	213	47	(	(	-LRB-
cord-298458-p7rvupjo	213	48	131	131	CD
cord-298458-p7rvupjo	213	49	)	)	-RRB-
cord-298458-p7rvupjo	213	50	.	.	.
cord-298458-p7rvupjo	214	1	Tregs	Tregs	NNP
cord-298458-p7rvupjo	214	2	also	also	RB
cord-298458-p7rvupjo	214	3	can	can	MD
cord-298458-p7rvupjo	214	4	suppress	suppress	VB
cord-298458-p7rvupjo	214	5	CD8	CD8	NNP
cord-298458-p7rvupjo	214	6	T	T	NNP
cord-298458-p7rvupjo	214	7	cell	cell	NN
cord-298458-p7rvupjo	214	8	effector	effector	NN
cord-298458-p7rvupjo	214	9	functions	function	NNS
cord-298458-p7rvupjo	214	10	following	follow	VBG
cord-298458-p7rvupjo	214	11	a	a	DT
cord-298458-p7rvupjo	214	12	secondary	secondary	JJ
cord-298458-p7rvupjo	214	13	infection	infection	NN
cord-298458-p7rvupjo	214	14	with	with	IN
cord-298458-p7rvupjo	214	15	IAV	IAV	NNP
cord-298458-p7rvupjo	214	16	(	(	-LRB-
cord-298458-p7rvupjo	214	17	130	130	CD
cord-298458-p7rvupjo	214	18	)	)	-RRB-
cord-298458-p7rvupjo	214	19	.	.	.
cord-298458-p7rvupjo	215	1	Antibody	antibody	NN
cord-298458-p7rvupjo	215	2	-	-	HYPH
cord-298458-p7rvupjo	215	3	mediated	mediate	VBN
cord-298458-p7rvupjo	215	4	CD25	CD25	NNP
cord-298458-p7rvupjo	215	5	+	+	CC
cord-298458-p7rvupjo	215	6	Treg	Treg	NNP
cord-298458-p7rvupjo	215	7	depletion	depletion	NN
cord-298458-p7rvupjo	215	8	prior	prior	RB
cord-298458-p7rvupjo	215	9	to	to	IN
cord-298458-p7rvupjo	215	10	heterosubtypic	heterosubtypic	NNP
cord-298458-p7rvupjo	215	11	IAV	IAV	NNP
cord-298458-p7rvupjo	215	12	challenge	challenge	NN
cord-298458-p7rvupjo	215	13	resulted	result	VBD
cord-298458-p7rvupjo	215	14	in	in	IN
cord-298458-p7rvupjo	215	15	enhanced	enhanced	JJ
cord-298458-p7rvupjo	215	16	inflammation	inflammation	NN
cord-298458-p7rvupjo	215	17	and	and	CC
cord-298458-p7rvupjo	215	18	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	215	19	dysfunction	dysfunction	NN
cord-298458-p7rvupjo	215	20	corresponding	correspond	VBG
cord-298458-p7rvupjo	215	21	to	to	IN
cord-298458-p7rvupjo	215	22	an	an	DT
cord-298458-p7rvupjo	215	23	increase	increase	NN
cord-298458-p7rvupjo	215	24	in	in	IN
cord-298458-p7rvupjo	215	25	CD8	CD8	NNP
cord-298458-p7rvupjo	215	26	T	T	NNP
cord-298458-p7rvupjo	215	27	cell	cell	NN
cord-298458-p7rvupjo	215	28	numbers	number	NNS
cord-298458-p7rvupjo	215	29	and	and	CC
cord-298458-p7rvupjo	215	30	IFN	IFN	NNP
cord-298458-p7rvupjo	215	31	-	-	HYPH
cord-298458-p7rvupjo	215	32	γ	γ	NNP
cord-298458-p7rvupjo	215	33	production	production	NN
cord-298458-p7rvupjo	215	34	.	.	.
cord-298458-p7rvupjo	216	1	One	one	CD
cord-298458-p7rvupjo	216	2	mechanism	mechanism	NN
cord-298458-p7rvupjo	216	3	through	through	IN
cord-298458-p7rvupjo	216	4	which	which	WDT
cord-298458-p7rvupjo	216	5	Tregs	Tregs	NNP
cord-298458-p7rvupjo	216	6	may	may	MD
cord-298458-p7rvupjo	216	7	suppress	suppress	VB
cord-298458-p7rvupjo	216	8	CD8	CD8	NNP
cord-298458-p7rvupjo	216	9	T	T	NNP
cord-298458-p7rvupjo	216	10	cell	cell	NN
cord-298458-p7rvupjo	216	11	responses	response	NNS
cord-298458-p7rvupjo	216	12	is	be	VBZ
cord-298458-p7rvupjo	216	13	through	through	IN
cord-298458-p7rvupjo	216	14	the	the	DT
cord-298458-p7rvupjo	216	15	production	production	NN
cord-298458-p7rvupjo	216	16	of	of	IN
cord-298458-p7rvupjo	216	17	the	the	DT
cord-298458-p7rvupjo	216	18	anti	anti	JJ
cord-298458-p7rvupjo	216	19	-	-	JJ
cord-298458-p7rvupjo	216	20	inflammatory	inflammatory	JJ
cord-298458-p7rvupjo	216	21	cytokine	cytokine	NN
cord-298458-p7rvupjo	216	22	IL-10	IL-10	NNP
cord-298458-p7rvupjo	216	23	.	.	.
cord-298458-p7rvupjo	217	1	FoxP3	foxp3	NN
cord-298458-p7rvupjo	217	2	+	+	CC
cord-298458-p7rvupjo	218	1	Tregs	Tregs	NNP
cord-298458-p7rvupjo	218	2	secrete	secrete	NN
cord-298458-p7rvupjo	218	3	IL-10	IL-10	NNP
cord-298458-p7rvupjo	218	4	following	follow	VBG
cord-298458-p7rvupjo	218	5	primary	primary	JJ
cord-298458-p7rvupjo	218	6	infection	infection	NN
cord-298458-p7rvupjo	218	7	with	with	IN
cord-298458-p7rvupjo	218	8	RSV	RSV	NNP
cord-298458-p7rvupjo	218	9	or	or	CC
cord-298458-p7rvupjo	218	10	IAV	IAV	NNP
cord-298458-p7rvupjo	218	11	(	(	-LRB-
cord-298458-p7rvupjo	218	12	130	130	CD
cord-298458-p7rvupjo	218	13	,	,	,
cord-298458-p7rvupjo	218	14	(	(	-LRB-
cord-298458-p7rvupjo	218	15	132	132	CD
cord-298458-p7rvupjo	218	16	)	)	-RRB-
cord-298458-p7rvupjo	218	17	(	(	-LRB-
cord-298458-p7rvupjo	218	18	133	133	CD
cord-298458-p7rvupjo	218	19	)	)	-RRB-
cord-298458-p7rvupjo	218	20	(	(	-LRB-
cord-298458-p7rvupjo	218	21	134	134	CD
cord-298458-p7rvupjo	218	22	)	)	-RRB-
cord-298458-p7rvupjo	218	23	.	.	.
cord-298458-p7rvupjo	219	1	Infection	infection	NN
cord-298458-p7rvupjo	219	2	of	of	IN
cord-298458-p7rvupjo	219	3	either	either	DT
cord-298458-p7rvupjo	219	4	IL-10-deficient	IL-10-deficient	NNP
cord-298458-p7rvupjo	219	5	mice	mouse	NNS
cord-298458-p7rvupjo	219	6	or	or	CC
cord-298458-p7rvupjo	219	7	mice	mouse	NNS
cord-298458-p7rvupjo	219	8	treated	treat	VBN
cord-298458-p7rvupjo	219	9	with	with	IN
cord-298458-p7rvupjo	219	10	IL-10	IL-10	NNP
cord-298458-p7rvupjo	219	11	receptor	receptor	NN
cord-298458-p7rvupjo	219	12	blocking	block	VBG
cord-298458-p7rvupjo	219	13	antibody	antibody	NN
cord-298458-p7rvupjo	219	14	resulted	result	VBD
cord-298458-p7rvupjo	219	15	in	in	IN
cord-298458-p7rvupjo	219	16	increased	increase	VBN
cord-298458-p7rvupjo	219	17	numbers	number	NNS
cord-298458-p7rvupjo	219	18	of	of	IN
cord-298458-p7rvupjo	219	19	either	either	CC
cord-298458-p7rvupjo	219	20	IFN	IFN	NNP
cord-298458-p7rvupjo	219	21	-	-	HYPH
cord-298458-p7rvupjo	219	22	γ	γ	NNP
cord-298458-p7rvupjo	219	23	+	+	CC
cord-298458-p7rvupjo	219	24	or	or	CC
cord-298458-p7rvupjo	219	25	IFN	IFN	NNP
cord-298458-p7rvupjo	219	26	-	-	HYPH
cord-298458-p7rvupjo	219	27	γ	γ	NNP
cord-298458-p7rvupjo	219	28	+	+	CC
cord-298458-p7rvupjo	219	29	TNF	TNF	NNP
cord-298458-p7rvupjo	219	30	+	+	SYM
cord-298458-p7rvupjo	219	31	CD8	CD8	NNP
cord-298458-p7rvupjo	219	32	T	T	NNP
cord-298458-p7rvupjo	219	33	cells	cell	NNS
cord-298458-p7rvupjo	219	34	,	,	,
cord-298458-p7rvupjo	219	35	suggesting	suggest	VBG
cord-298458-p7rvupjo	219	36	that	that	IN
cord-298458-p7rvupjo	219	37	IL-10	IL-10	NNP
cord-298458-p7rvupjo	219	38	suppresses	suppress	VBZ
cord-298458-p7rvupjo	219	39	CD8	CD8	NNP
cord-298458-p7rvupjo	219	40	T	T	NNP
cord-298458-p7rvupjo	219	41	cell	cell	NN
cord-298458-p7rvupjo	219	42	effector	effector	NN
cord-298458-p7rvupjo	219	43	functions	function	NNS
cord-298458-p7rvupjo	219	44	following	follow	VBG
cord-298458-p7rvupjo	219	45	respiratory	respiratory	JJ
cord-298458-p7rvupjo	219	46	virus	virus	NN
cord-298458-p7rvupjo	219	47	infection	infection	NN
cord-298458-p7rvupjo	219	48	(	(	-LRB-
cord-298458-p7rvupjo	219	49	132	132	CD
cord-298458-p7rvupjo	219	50	)	)	-RRB-
cord-298458-p7rvupjo	219	51	(	(	-LRB-
cord-298458-p7rvupjo	219	52	133	133	CD
cord-298458-p7rvupjo	219	53	)	)	-RRB-
cord-298458-p7rvupjo	219	54	(	(	-LRB-
cord-298458-p7rvupjo	219	55	134	134	CD
cord-298458-p7rvupjo	219	56	)	)	-RRB-
cord-298458-p7rvupjo	219	57	.	.	.
cord-298458-p7rvupjo	220	1	Interestingly	interestingly	RB
cord-298458-p7rvupjo	220	2	,	,	,
cord-298458-p7rvupjo	220	3	IL-10	IL-10	NNP
cord-298458-p7rvupjo	220	4	production	production	NN
cord-298458-p7rvupjo	220	5	by	by	IN
cord-298458-p7rvupjo	220	6	FoxP3	FoxP3	NNP
cord-298458-p7rvupjo	220	7	−	−	NNP
cord-298458-p7rvupjo	220	8	CD4	CD4	NNP
cord-298458-p7rvupjo	220	9	T	T	NNP
cord-298458-p7rvupjo	220	10	cells	cell	NNS
cord-298458-p7rvupjo	220	11	and	and	CC
cord-298458-p7rvupjo	220	12	CD8	CD8	NNP
cord-298458-p7rvupjo	220	13	T	T	NNP
cord-298458-p7rvupjo	220	14	cells	cell	NNS
cord-298458-p7rvupjo	220	15	following	follow	VBG
cord-298458-p7rvupjo	220	16	either	either	CC
cord-298458-p7rvupjo	220	17	RSV	RSV	NNP
cord-298458-p7rvupjo	220	18	or	or	CC
cord-298458-p7rvupjo	220	19	IAV	IAV	NNP
cord-298458-p7rvupjo	220	20	infection	infection	NN
cord-298458-p7rvupjo	220	21	has	have	VBZ
cord-298458-p7rvupjo	220	22	also	also	RB
cord-298458-p7rvupjo	220	23	been	be	VBN
cord-298458-p7rvupjo	220	24	reported	report	VBN
cord-298458-p7rvupjo	220	25	,	,	,
cord-298458-p7rvupjo	220	26	indicating	indicate	VBG
cord-298458-p7rvupjo	220	27	that	that	IN
cord-298458-p7rvupjo	220	28	effector	effector	NN
cord-298458-p7rvupjo	220	29	T	t	NN
cord-298458-p7rvupjo	220	30	cell	cell	NN
cord-298458-p7rvupjo	220	31	responses	response	NNS
cord-298458-p7rvupjo	220	32	may	may	MD
cord-298458-p7rvupjo	220	33	self	self	NN
cord-298458-p7rvupjo	220	34	-	-	HYPH
cord-298458-p7rvupjo	220	35	regulate	regulate	VB
cord-298458-p7rvupjo	220	36	their	-PRON-	PRP$
cord-298458-p7rvupjo	220	37	effector	effector	NN
cord-298458-p7rvupjo	220	38	functions	function	NNS
cord-298458-p7rvupjo	220	39	(	(	-LRB-
cord-298458-p7rvupjo	220	40	132	132	CD
cord-298458-p7rvupjo	220	41	)	)	-RRB-
cord-298458-p7rvupjo	220	42	(	(	-LRB-
cord-298458-p7rvupjo	220	43	133	133	CD
cord-298458-p7rvupjo	220	44	)	)	-RRB-
cord-298458-p7rvupjo	220	45	(	(	-LRB-
cord-298458-p7rvupjo	220	46	134	134	CD
cord-298458-p7rvupjo	220	47	)	)	-RRB-
cord-298458-p7rvupjo	220	48	(	(	-LRB-
cord-298458-p7rvupjo	220	49	135	135	CD
cord-298458-p7rvupjo	220	50	)	)	-RRB-
cord-298458-p7rvupjo	220	51	.	.	.
cord-298458-p7rvupjo	221	1	Together	together	RB
cord-298458-p7rvupjo	221	2	,	,	,
cord-298458-p7rvupjo	221	3	these	these	DT
cord-298458-p7rvupjo	221	4	studies	study	NNS
cord-298458-p7rvupjo	221	5	demonstrate	demonstrate	VBP
cord-298458-p7rvupjo	221	6	that	that	IN
cord-298458-p7rvupjo	221	7	Tregs	Tregs	NNP
cord-298458-p7rvupjo	221	8	and	and	CC
cord-298458-p7rvupjo	221	9	IL-10	IL-10	NNP
cord-298458-p7rvupjo	221	10	production	production	NN
cord-298458-p7rvupjo	221	11	play	play	VBP
cord-298458-p7rvupjo	221	12	a	a	DT
cord-298458-p7rvupjo	221	13	critical	critical	JJ
cord-298458-p7rvupjo	221	14	role	role	NN
cord-298458-p7rvupjo	221	15	in	in	IN
cord-298458-p7rvupjo	221	16	regulating	regulate	VBG
cord-298458-p7rvupjo	221	17	CD8	CD8	NNP
cord-298458-p7rvupjo	221	18	T	T	NNP
cord-298458-p7rvupjo	221	19	cells	cell	NNS
cord-298458-p7rvupjo	221	20	following	follow	VBG
cord-298458-p7rvupjo	221	21	primary	primary	JJ
cord-298458-p7rvupjo	221	22	and	and	CC
cord-298458-p7rvupjo	221	23	secondary	secondary	JJ
cord-298458-p7rvupjo	221	24	respiratory	respiratory	JJ
cord-298458-p7rvupjo	221	25	virus	virus	NN
cord-298458-p7rvupjo	221	26	infections	infection	NNS
cord-298458-p7rvupjo	221	27	to	to	TO
cord-298458-p7rvupjo	221	28	prevent	prevent	VB
cord-298458-p7rvupjo	221	29	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	221	30	.	.	.
cord-298458-p7rvupjo	222	1	Interactions	interaction	NNS
cord-298458-p7rvupjo	222	2	between	between	IN
cord-298458-p7rvupjo	222	3	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	222	4	receptors	receptor	NNS
cord-298458-p7rvupjo	222	5	on	on	IN
cord-298458-p7rvupjo	222	6	CD8	CD8	NNP
cord-298458-p7rvupjo	222	7	T	T	NNP
cord-298458-p7rvupjo	222	8	cells	cell	NNS
cord-298458-p7rvupjo	222	9	with	with	IN
cord-298458-p7rvupjo	222	10	their	-PRON-	PRP$
cord-298458-p7rvupjo	222	11	ligands	ligand	NNS
cord-298458-p7rvupjo	222	12	represents	represent	VBZ
cord-298458-p7rvupjo	222	13	another	another	DT
cord-298458-p7rvupjo	222	14	important	important	JJ
cord-298458-p7rvupjo	222	15	mechanism	mechanism	NN
cord-298458-p7rvupjo	222	16	mediating	mediate	VBG
cord-298458-p7rvupjo	222	17	the	the	DT
cord-298458-p7rvupjo	222	18	inhibition	inhibition	NN
cord-298458-p7rvupjo	222	19	of	of	IN
cord-298458-p7rvupjo	222	20	CD8	CD8	NNP
cord-298458-p7rvupjo	222	21	T	T	NNP
cord-298458-p7rvupjo	222	22	cell	cell	NN
cord-298458-p7rvupjo	222	23	effector	effector	NN
cord-298458-p7rvupjo	222	24	functions	function	NNS
cord-298458-p7rvupjo	222	25	following	follow	VBG
cord-298458-p7rvupjo	222	26	infection	infection	NN
cord-298458-p7rvupjo	222	27	.	.	.
cord-298458-p7rvupjo	223	1	Regulation	regulation	NN
cord-298458-p7rvupjo	223	2	of	of	IN
cord-298458-p7rvupjo	223	3	CD8	CD8	NNP
cord-298458-p7rvupjo	223	4	T	T	NNP
cord-298458-p7rvupjo	223	5	cells	cell	NNS
cord-298458-p7rvupjo	223	6	through	through	IN
cord-298458-p7rvupjo	223	7	the	the	DT
cord-298458-p7rvupjo	223	8	PD-1	PD-1	NNP
cord-298458-p7rvupjo	223	9	:	:	:
cord-298458-p7rvupjo	224	1	PD	PD	NNP
cord-298458-p7rvupjo	224	2	-	-	HYPH
cord-298458-p7rvupjo	224	3	L1	L1	NNP
cord-298458-p7rvupjo	224	4	pathway	pathway	NN
cord-298458-p7rvupjo	224	5	is	be	VBZ
cord-298458-p7rvupjo	224	6	a	a	DT
cord-298458-p7rvupjo	224	7	common	common	JJ
cord-298458-p7rvupjo	224	8	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	224	9	pathway	pathway	NN
cord-298458-p7rvupjo	224	10	utilized	utilize	VBN
cord-298458-p7rvupjo	224	11	following	follow	VBG
cord-298458-p7rvupjo	224	12	respiratory	respiratory	JJ
cord-298458-p7rvupjo	224	13	virus	virus	NN
cord-298458-p7rvupjo	224	14	infection	infection	NN
cord-298458-p7rvupjo	224	15	.	.	.
cord-298458-p7rvupjo	225	1	Expression	expression	NN
cord-298458-p7rvupjo	225	2	of	of	IN
cord-298458-p7rvupjo	225	3	PD-1	PD-1	NNP
cord-298458-p7rvupjo	225	4	on	on	IN
cord-298458-p7rvupjo	225	5	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	225	6	CD8	CD8	NNP
cord-298458-p7rvupjo	225	7	T	T	NNP
cord-298458-p7rvupjo	225	8	cells	cell	NNS
cord-298458-p7rvupjo	225	9	is	be	VBZ
cord-298458-p7rvupjo	225	10	upregulated	upregulate	VBN
cord-298458-p7rvupjo	225	11	following	follow	VBG
cord-298458-p7rvupjo	225	12	RSV	RSV	NNP
cord-298458-p7rvupjo	225	13	,	,	,
cord-298458-p7rvupjo	225	14	IAV	IAV	NNP
cord-298458-p7rvupjo	225	15	,	,	,
cord-298458-p7rvupjo	225	16	or	or	CC
cord-298458-p7rvupjo	225	17	HMPV	hmpv	NN
cord-298458-p7rvupjo	225	18	infection	infection	NN
cord-298458-p7rvupjo	225	19	in	in	IN
cord-298458-p7rvupjo	225	20	mice	mouse	NNS
cord-298458-p7rvupjo	225	21	(	(	-LRB-
cord-298458-p7rvupjo	225	22	41	41	CD
cord-298458-p7rvupjo	225	23	,	,	,
cord-298458-p7rvupjo	225	24	136	136	CD
cord-298458-p7rvupjo	225	25	,	,	,
cord-298458-p7rvupjo	225	26	137	137	CD
cord-298458-p7rvupjo	225	27	)	)	-RRB-
cord-298458-p7rvupjo	225	28	.	.	.
cord-298458-p7rvupjo	226	1	Blockade	blockade	NN
cord-298458-p7rvupjo	226	2	of	of	IN
cord-298458-p7rvupjo	226	3	PD	PD	NNP
cord-298458-p7rvupjo	226	4	-	-	HYPH
cord-298458-p7rvupjo	226	5	L1	L1	NNP
cord-298458-p7rvupjo	226	6	in	in	IN
cord-298458-p7rvupjo	226	7	primary	primary	JJ
cord-298458-p7rvupjo	226	8	RSV	RSV	NNP
cord-298458-p7rvupjo	226	9	,	,	,
cord-298458-p7rvupjo	226	10	IAV	IAV	NNP
cord-298458-p7rvupjo	226	11	,	,	,
cord-298458-p7rvupjo	226	12	or	or	CC
cord-298458-p7rvupjo	226	13	HMPV	hmpv	NN
cord-298458-p7rvupjo	226	14	and	and	CC
cord-298458-p7rvupjo	226	15	secondary	secondary	JJ
cord-298458-p7rvupjo	226	16	HMPV	HMPV	NNP
cord-298458-p7rvupjo	226	17	infections	infection	NNS
cord-298458-p7rvupjo	226	18	results	result	NNS
cord-298458-p7rvupjo	226	19	in	in	IN
cord-298458-p7rvupjo	226	20	enhanced	enhanced	JJ
cord-298458-p7rvupjo	226	21	CD8	CD8	NNP
cord-298458-p7rvupjo	226	22	T	T	NNP
cord-298458-p7rvupjo	226	23	cell	cell	NN
cord-298458-p7rvupjo	226	24	effector	effector	NN
cord-298458-p7rvupjo	226	25	functions	function	NNS
cord-298458-p7rvupjo	226	26	,	,	,
cord-298458-p7rvupjo	226	27	including	include	VBG
cord-298458-p7rvupjo	226	28	IFN	IFN	NNP
cord-298458-p7rvupjo	226	29	-	-	HYPH
cord-298458-p7rvupjo	226	30	γ	γ	NNP
cord-298458-p7rvupjo	226	31	,	,	,
cord-298458-p7rvupjo	226	32	TNF	TNF	NNP
cord-298458-p7rvupjo	226	33	,	,	,
cord-298458-p7rvupjo	226	34	and	and	CC
cord-298458-p7rvupjo	226	35	granzyme	granzyme	NNP
cord-298458-p7rvupjo	226	36	B	B	NNP
cord-298458-p7rvupjo	226	37	production	production	NN
cord-298458-p7rvupjo	226	38	(	(	-LRB-
cord-298458-p7rvupjo	226	39	41	41	CD
cord-298458-p7rvupjo	226	40	,	,	,
cord-298458-p7rvupjo	226	41	[	[	-LRB-
cord-298458-p7rvupjo	226	42	136	136	CD
cord-298458-p7rvupjo	226	43	]	]	-RRB-
cord-298458-p7rvupjo	227	1	[	[	-LRB-
cord-298458-p7rvupjo	227	2	137	137	CD
cord-298458-p7rvupjo	227	3	]	]	-RRB-
cord-298458-p7rvupjo	228	1	[	[	-LRB-
cord-298458-p7rvupjo	228	2	138	138	CD
cord-298458-p7rvupjo	228	3	]	]	-RRB-
cord-298458-p7rvupjo	228	4	.	.	.
cord-298458-p7rvupjo	229	1	CD8	CD8	NNP
cord-298458-p7rvupjo	229	2	T	T	NNP
cord-298458-p7rvupjo	229	3	cell	cell	NN
cord-298458-p7rvupjo	229	4	effector	effector	NN
cord-298458-p7rvupjo	229	5	functions	function	NNS
cord-298458-p7rvupjo	229	6	are	be	VBP
cord-298458-p7rvupjo	229	7	also	also	RB
cord-298458-p7rvupjo	229	8	enhanced	enhance	VBN
cord-298458-p7rvupjo	229	9	following	follow	VBG
cord-298458-p7rvupjo	229	10	either	either	CC
cord-298458-p7rvupjo	229	11	HMPV	HMPV	NNP
cord-298458-p7rvupjo	229	12	or	or	CC
cord-298458-p7rvupjo	229	13	IAV	IAV	NNP
cord-298458-p7rvupjo	229	14	infections	infection	NNS
cord-298458-p7rvupjo	229	15	in	in	IN
cord-298458-p7rvupjo	229	16	PD-1-deficient	pd-1-deficient	CD
cord-298458-p7rvupjo	229	17	mice	mouse	NNS
cord-298458-p7rvupjo	229	18	(	(	-LRB-
cord-298458-p7rvupjo	229	19	41	41	CD
cord-298458-p7rvupjo	229	20	)	)	-RRB-
cord-298458-p7rvupjo	229	21	.	.	.
cord-298458-p7rvupjo	230	1	Importantly	importantly	RB
cord-298458-p7rvupjo	230	2	,	,	,
cord-298458-p7rvupjo	230	3	the	the	DT
cord-298458-p7rvupjo	230	4	PD-1	PD-1	NNP
cord-298458-p7rvupjo	230	5	:	:	:
cord-298458-p7rvupjo	230	6	PD	PD	NNP
cord-298458-p7rvupjo	230	7	-	-	HYPH
cord-298458-p7rvupjo	230	8	L1	L1	NNP
cord-298458-p7rvupjo	230	9	pathway	pathway	NN
cord-298458-p7rvupjo	230	10	has	have	VBZ
cord-298458-p7rvupjo	230	11	also	also	RB
cord-298458-p7rvupjo	230	12	been	be	VBN
cord-298458-p7rvupjo	230	13	associated	associate	VBN
cord-298458-p7rvupjo	230	14	with	with	IN
cord-298458-p7rvupjo	230	15	human	human	JJ
cord-298458-p7rvupjo	230	16	CD8	CD8	NNP
cord-298458-p7rvupjo	230	17	T	T	NNP
cord-298458-p7rvupjo	230	18	cell	cell	NN
cord-298458-p7rvupjo	230	19	responses	response	NNS
cord-298458-p7rvupjo	230	20	.	.	.
cord-298458-p7rvupjo	231	1	Human	human	JJ
cord-298458-p7rvupjo	231	2	CD8	CD8	NNP
cord-298458-p7rvupjo	231	3	T	T	NNP
cord-298458-p7rvupjo	231	4	cells	cell	NNS
cord-298458-p7rvupjo	231	5	in	in	IN
cord-298458-p7rvupjo	231	6	the	the	DT
cord-298458-p7rvupjo	231	7	nasal	nasal	NN
cord-298458-p7rvupjo	231	8	cavity	cavity	NN
cord-298458-p7rvupjo	231	9	significantly	significantly	RB
cord-298458-p7rvupjo	231	10	upregulated	upregulate	VBD
cord-298458-p7rvupjo	231	11	PD-1	PD-1	NNP
cord-298458-p7rvupjo	231	12	following	follow	VBG
cord-298458-p7rvupjo	231	13	RSV	RSV	NNP
cord-298458-p7rvupjo	231	14	infection	infection	NN
cord-298458-p7rvupjo	231	15	compared	compare	VBN
cord-298458-p7rvupjo	231	16	to	to	IN
cord-298458-p7rvupjo	231	17	CD8	CD8	NNP
cord-298458-p7rvupjo	231	18	T	T	NNP
cord-298458-p7rvupjo	231	19	cells	cell	NNS
cord-298458-p7rvupjo	231	20	from	from	IN
cord-298458-p7rvupjo	231	21	the	the	DT
cord-298458-p7rvupjo	231	22	blood	blood	NN
cord-298458-p7rvupjo	231	23	of	of	IN
cord-298458-p7rvupjo	231	24	either	either	CC
cord-298458-p7rvupjo	231	25	healthy	healthy	JJ
cord-298458-p7rvupjo	231	26	or	or	CC
cord-298458-p7rvupjo	231	27	RSV	RSV	NNP
cord-298458-p7rvupjo	231	28	-	-	HYPH
cord-298458-p7rvupjo	231	29	infected	infect	VBN
cord-298458-p7rvupjo	231	30	individuals	individual	NNS
cord-298458-p7rvupjo	231	31	(	(	-LRB-
cord-298458-p7rvupjo	231	32	137	137	CD
cord-298458-p7rvupjo	231	33	)	)	-RRB-
cord-298458-p7rvupjo	231	34	.	.	.
cord-298458-p7rvupjo	232	1	PD-1	PD-1	NNP
cord-298458-p7rvupjo	233	1	and	and	CC
cord-298458-p7rvupjo	233	2	PD	PD	NNP
cord-298458-p7rvupjo	233	3	-	-	HYPH
cord-298458-p7rvupjo	233	4	L1	L1	NNP
cord-298458-p7rvupjo	233	5	are	be	VBP
cord-298458-p7rvupjo	233	6	also	also	RB
cord-298458-p7rvupjo	233	7	both	both	DT
cord-298458-p7rvupjo	233	8	upregulated	upregulate	VBN
cord-298458-p7rvupjo	233	9	in	in	IN
cord-298458-p7rvupjo	233	10	the	the	DT
cord-298458-p7rvupjo	233	11	lung	lung	NN
cord-298458-p7rvupjo	233	12	FiGURe	FiGURe	NNP
cord-298458-p7rvupjo	233	13	1	1	CD
cord-298458-p7rvupjo	233	14	|	|	NNP
cord-298458-p7rvupjo	233	15	Critical	critical	JJ
cord-298458-p7rvupjo	233	16	factors	factor	NNS
cord-298458-p7rvupjo	233	17	for	for	IN
cord-298458-p7rvupjo	233	18	an	an	DT
cord-298458-p7rvupjo	233	19	optimal	optimal	JJ
cord-298458-p7rvupjo	233	20	CD8	CD8	NNP
cord-298458-p7rvupjo	233	21	T	T	NNP
cord-298458-p7rvupjo	233	22	cell	cell	NN
cord-298458-p7rvupjo	233	23	-	-	HYPH
cord-298458-p7rvupjo	233	24	mediated	mediate	VBN
cord-298458-p7rvupjo	233	25	respiratory	respiratory	JJ
cord-298458-p7rvupjo	233	26	syncytial	syncytial	JJ
cord-298458-p7rvupjo	233	27	virus	virus	NN
cord-298458-p7rvupjo	233	28	(	(	-LRB-
cord-298458-p7rvupjo	233	29	RSV	RSV	NNP
cord-298458-p7rvupjo	233	30	)	)	-RRB-
cord-298458-p7rvupjo	233	31	vaccine	vaccine	NN
cord-298458-p7rvupjo	233	32	.	.	.
cord-298458-p7rvupjo	234	1	A	a	DT
cord-298458-p7rvupjo	234	2	future	future	JJ
cord-298458-p7rvupjo	234	3	RSV	RSV	NNP
cord-298458-p7rvupjo	234	4	vaccine	vaccine	NN
cord-298458-p7rvupjo	234	5	designed	design	VBN
cord-298458-p7rvupjo	234	6	to	to	TO
cord-298458-p7rvupjo	234	7	elicit	elicit	VB
cord-298458-p7rvupjo	234	8	a	a	DT
cord-298458-p7rvupjo	234	9	CD8	CD8	NNP
cord-298458-p7rvupjo	234	10	T	T	NNP
cord-298458-p7rvupjo	234	11	cell	cell	NN
cord-298458-p7rvupjo	234	12	response	response	NN
cord-298458-p7rvupjo	234	13	will	will	MD
cord-298458-p7rvupjo	234	14	require	require	VB
cord-298458-p7rvupjo	234	15	a	a	DT
cord-298458-p7rvupjo	234	16	balance	balance	NN
cord-298458-p7rvupjo	234	17	between	between	IN
cord-298458-p7rvupjo	234	18	CD8	CD8	NNP
cord-298458-p7rvupjo	234	19	T	T	NNP
cord-298458-p7rvupjo	234	20	cell	cell	NN
cord-298458-p7rvupjo	234	21	-	-	HYPH
cord-298458-p7rvupjo	234	22	mediated	mediate	VBN
cord-298458-p7rvupjo	234	23	protection	protection	NN
cord-298458-p7rvupjo	234	24	and	and	CC
cord-298458-p7rvupjo	234	25	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	234	26	,	,	,
cord-298458-p7rvupjo	234	27	which	which	WDT
cord-298458-p7rvupjo	234	28	may	may	MD
cord-298458-p7rvupjo	234	29	be	be	VB
cord-298458-p7rvupjo	234	30	achieved	achieve	VBN
cord-298458-p7rvupjo	234	31	through	through	IN
cord-298458-p7rvupjo	234	32	the	the	DT
cord-298458-p7rvupjo	234	33	consideration	consideration	NN
cord-298458-p7rvupjo	234	34	of	of	IN
cord-298458-p7rvupjo	234	35	three	three	CD
cord-298458-p7rvupjo	234	36	important	important	JJ
cord-298458-p7rvupjo	234	37	aspects	aspect	NNS
cord-298458-p7rvupjo	234	38	:	:	:
cord-298458-p7rvupjo	234	39	(	(	-LRB-
cord-298458-p7rvupjo	234	40	1	1	LS
cord-298458-p7rvupjo	234	41	)	)	-RRB-
cord-298458-p7rvupjo	234	42	magnitude	magnitude	NN
cord-298458-p7rvupjo	234	43	,	,	,
cord-298458-p7rvupjo	234	44	(	(	-LRB-
cord-298458-p7rvupjo	234	45	2	2	LS
cord-298458-p7rvupjo	234	46	)	)	-RRB-
cord-298458-p7rvupjo	234	47	localization	localization	NN
cord-298458-p7rvupjo	234	48	,	,	,
cord-298458-p7rvupjo	234	49	and	and	CC
cord-298458-p7rvupjo	234	50	(	(	-LRB-
cord-298458-p7rvupjo	234	51	3	3	LS
cord-298458-p7rvupjo	234	52	)	)	-RRB-
cord-298458-p7rvupjo	234	53	regulation	regulation	NN
cord-298458-p7rvupjo	234	54	.	.	.
cord-298458-p7rvupjo	235	1	An	an	DT
cord-298458-p7rvupjo	235	2	optimal	optimal	JJ
cord-298458-p7rvupjo	235	3	magnitude	magnitude	NN
cord-298458-p7rvupjo	235	4	of	of	IN
cord-298458-p7rvupjo	235	5	the	the	DT
cord-298458-p7rvupjo	235	6	CD8	CD8	NNP
cord-298458-p7rvupjo	235	7	T	T	NNP
cord-298458-p7rvupjo	235	8	cell	cell	NN
cord-298458-p7rvupjo	235	9	response	response	NN
cord-298458-p7rvupjo	235	10	will	will	MD
cord-298458-p7rvupjo	235	11	be	be	VB
cord-298458-p7rvupjo	235	12	one	one	CD
cord-298458-p7rvupjo	235	13	that	that	WDT
cord-298458-p7rvupjo	235	14	achieves	achieve	VBZ
cord-298458-p7rvupjo	235	15	efficient	efficient	JJ
cord-298458-p7rvupjo	235	16	viral	viral	JJ
cord-298458-p7rvupjo	235	17	clearance	clearance	NN
cord-298458-p7rvupjo	235	18	in	in	IN
cord-298458-p7rvupjo	235	19	the	the	DT
cord-298458-p7rvupjo	235	20	absence	absence	NN
cord-298458-p7rvupjo	235	21	of	of	IN
cord-298458-p7rvupjo	235	22	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	235	23	.	.	.
cord-298458-p7rvupjo	236	1	The	the	DT
cord-298458-p7rvupjo	236	2	vaccination	vaccination	NN
cord-298458-p7rvupjo	236	3	route	route	NN
cord-298458-p7rvupjo	236	4	will	will	MD
cord-298458-p7rvupjo	236	5	be	be	VB
cord-298458-p7rvupjo	236	6	critical	critical	JJ
cord-298458-p7rvupjo	236	7	in	in	IN
cord-298458-p7rvupjo	236	8	determining	determine	VBG
cord-298458-p7rvupjo	236	9	the	the	DT
cord-298458-p7rvupjo	236	10	localization	localization	NN
cord-298458-p7rvupjo	236	11	of	of	IN
cord-298458-p7rvupjo	236	12	the	the	DT
cord-298458-p7rvupjo	236	13	CD8	CD8	NNP
cord-298458-p7rvupjo	236	14	T	T	NNP
cord-298458-p7rvupjo	236	15	cell	cell	NN
cord-298458-p7rvupjo	236	16	response	response	NN
cord-298458-p7rvupjo	236	17	.	.	.
cord-298458-p7rvupjo	237	1	A	a	DT
cord-298458-p7rvupjo	237	2	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	237	3	route	route	NN
cord-298458-p7rvupjo	237	4	of	of	IN
cord-298458-p7rvupjo	237	5	vaccination	vaccination	NN
cord-298458-p7rvupjo	237	6	will	will	MD
cord-298458-p7rvupjo	237	7	induce	induce	VB
cord-298458-p7rvupjo	237	8	TRM	TRM	NNP
cord-298458-p7rvupjo	237	9	in	in	IN
cord-298458-p7rvupjo	237	10	the	the	DT
cord-298458-p7rvupjo	237	11	lung	lung	NN
cord-298458-p7rvupjo	237	12	that	that	WDT
cord-298458-p7rvupjo	237	13	provides	provide	VBZ
cord-298458-p7rvupjo	237	14	superior	superior	JJ
cord-298458-p7rvupjo	237	15	protection	protection	NN
cord-298458-p7rvupjo	237	16	compared	compare	VBN
cord-298458-p7rvupjo	237	17	to	to	IN
cord-298458-p7rvupjo	237	18	a	a	DT
cord-298458-p7rvupjo	237	19	systemic	systemic	JJ
cord-298458-p7rvupjo	237	20	immunization	immunization	NN
cord-298458-p7rvupjo	237	21	that	that	WDT
cord-298458-p7rvupjo	237	22	would	would	MD
cord-298458-p7rvupjo	237	23	likely	likely	RB
cord-298458-p7rvupjo	237	24	not	not	RB
cord-298458-p7rvupjo	237	25	generate	generate	VB
cord-298458-p7rvupjo	237	26	protective	protective	JJ
cord-298458-p7rvupjo	237	27	TRM	trm	NN
cord-298458-p7rvupjo	237	28	.	.	.
cord-298458-p7rvupjo	238	1	Lastly	lastly	RB
cord-298458-p7rvupjo	238	2	,	,	,
cord-298458-p7rvupjo	238	3	regulation	regulation	NN
cord-298458-p7rvupjo	238	4	of	of	IN
cord-298458-p7rvupjo	238	5	the	the	DT
cord-298458-p7rvupjo	238	6	CD8	CD8	NNP
cord-298458-p7rvupjo	238	7	T	T	NNP
cord-298458-p7rvupjo	238	8	cell	cell	NN
cord-298458-p7rvupjo	238	9	response	response	NN
cord-298458-p7rvupjo	238	10	generated	generate	VBN
cord-298458-p7rvupjo	238	11	through	through	IN
cord-298458-p7rvupjo	238	12	vaccination	vaccination	NN
cord-298458-p7rvupjo	238	13	will	will	MD
cord-298458-p7rvupjo	238	14	be	be	VB
cord-298458-p7rvupjo	238	15	crucial	crucial	JJ
cord-298458-p7rvupjo	238	16	,	,	,
cord-298458-p7rvupjo	238	17	as	as	IN
cord-298458-p7rvupjo	238	18	uncontrolled	uncontrolled	JJ
cord-298458-p7rvupjo	238	19	effector	effector	NN
cord-298458-p7rvupjo	238	20	functions	function	NNS
cord-298458-p7rvupjo	238	21	,	,	,
cord-298458-p7rvupjo	238	22	particularly	particularly	RB
cord-298458-p7rvupjo	238	23	IFN	IFN	NNP
cord-298458-p7rvupjo	238	24	-	-	HYPH
cord-298458-p7rvupjo	238	25	γ	γ	NN
cord-298458-p7rvupjo	238	26	production	production	NN
cord-298458-p7rvupjo	238	27	,	,	,
cord-298458-p7rvupjo	238	28	can	can	MD
cord-298458-p7rvupjo	238	29	result	result	VB
cord-298458-p7rvupjo	238	30	in	in	IN
cord-298458-p7rvupjo	238	31	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	238	32	.	.	.
cord-298458-p7rvupjo	239	1	Frontiers	frontier	NNS
cord-298458-p7rvupjo	239	2	in	in	IN
cord-298458-p7rvupjo	239	3	Immunology	Immunology	NNP
cord-298458-p7rvupjo	239	4	|	|	NNP
cord-298458-p7rvupjo	239	5	www.frontiersin.org	www.frontiersin.org	IN
cord-298458-p7rvupjo	239	6	April	April	NNP
cord-298458-p7rvupjo	239	7	2018	2018	CD
cord-298458-p7rvupjo	240	1	|	|	NNP
cord-298458-p7rvupjo	240	2	Volume	Volume	NNP
cord-298458-p7rvupjo	240	3	9	9	CD
cord-298458-p7rvupjo	240	4	|	|	NNP
cord-298458-p7rvupjo	240	5	Article	article	NN
cord-298458-p7rvupjo	240	6	678	678	CD
cord-298458-p7rvupjo	240	7	tissue	tissue	NN
cord-298458-p7rvupjo	240	8	following	follow	VBG
cord-298458-p7rvupjo	240	9	severe	severe	JJ
cord-298458-p7rvupjo	240	10	infections	infection	NNS
cord-298458-p7rvupjo	240	11	with	with	IN
cord-298458-p7rvupjo	240	12	either	either	CC
cord-298458-p7rvupjo	240	13	RSV	RSV	NNP
cord-298458-p7rvupjo	240	14	or	or	CC
cord-298458-p7rvupjo	240	15	the	the	DT
cord-298458-p7rvupjo	240	16	2009	2009	CD
cord-298458-p7rvupjo	240	17	H1N1	H1N1	NNP
cord-298458-p7rvupjo	240	18	IAV	IAV	NNP
cord-298458-p7rvupjo	240	19	pandemic	pandemic	NN
cord-298458-p7rvupjo	240	20	strain	strain	NN
cord-298458-p7rvupjo	240	21	(	(	-LRB-
cord-298458-p7rvupjo	240	22	41	41	CD
cord-298458-p7rvupjo	240	23	)	)	-RRB-
cord-298458-p7rvupjo	240	24	.	.	.
cord-298458-p7rvupjo	241	1	In	in	IN
cord-298458-p7rvupjo	241	2	vitro	vitro	FW
cord-298458-p7rvupjo	241	3	human	human	JJ
cord-298458-p7rvupjo	241	4	studies	study	NNS
cord-298458-p7rvupjo	241	5	have	have	VBP
cord-298458-p7rvupjo	241	6	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	241	7	that	that	IN
cord-298458-p7rvupjo	241	8	PD	PD	NNP
cord-298458-p7rvupjo	241	9	-	-	HYPH
cord-298458-p7rvupjo	241	10	L1	L1	NNP
cord-298458-p7rvupjo	241	11	is	be	VBZ
cord-298458-p7rvupjo	241	12	constitutively	constitutively	RB
cord-298458-p7rvupjo	241	13	expressed	express	VBN
cord-298458-p7rvupjo	241	14	on	on	IN
cord-298458-p7rvupjo	241	15	human	human	JJ
cord-298458-p7rvupjo	241	16	airway	airway	NN
cord-298458-p7rvupjo	241	17	and	and	CC
cord-298458-p7rvupjo	241	18	bronchial	bronchial	JJ
cord-298458-p7rvupjo	241	19	epithelial	epithelial	JJ
cord-298458-p7rvupjo	241	20	cells	cell	NNS
cord-298458-p7rvupjo	241	21	,	,	,
cord-298458-p7rvupjo	241	22	but	but	CC
cord-298458-p7rvupjo	241	23	expression	expression	NN
cord-298458-p7rvupjo	241	24	is	be	VBZ
cord-298458-p7rvupjo	241	25	significantly	significantly	RB
cord-298458-p7rvupjo	241	26	upregulated	upregulate	VBN
cord-298458-p7rvupjo	241	27	following	follow	VBG
cord-298458-p7rvupjo	241	28	either	either	CC
cord-298458-p7rvupjo	241	29	IAV	IAV	NNP
cord-298458-p7rvupjo	241	30	or	or	CC
cord-298458-p7rvupjo	241	31	RSV	RSV	NNP
cord-298458-p7rvupjo	241	32	infection	infection	NN
cord-298458-p7rvupjo	241	33	(	(	-LRB-
cord-298458-p7rvupjo	241	34	136	136	CD
cord-298458-p7rvupjo	241	35	,	,	,
cord-298458-p7rvupjo	241	36	139	139	CD
cord-298458-p7rvupjo	241	37	)	)	-RRB-
cord-298458-p7rvupjo	241	38	.	.	.
cord-298458-p7rvupjo	242	1	Similar	similar	JJ
cord-298458-p7rvupjo	242	2	to	to	IN
cord-298458-p7rvupjo	242	3	in	in	IN
cord-298458-p7rvupjo	242	4	vivo	vivo	NNP
cord-298458-p7rvupjo	242	5	mouse	mouse	NN
cord-298458-p7rvupjo	242	6	studies	study	NNS
cord-298458-p7rvupjo	242	7	,	,	,
cord-298458-p7rvupjo	242	8	in	in	IN
cord-298458-p7rvupjo	242	9	vitro	vitro	FW
cord-298458-p7rvupjo	242	10	PD	PD	NNP
cord-298458-p7rvupjo	242	11	-	-	HYPH
cord-298458-p7rvupjo	242	12	L1	L1	NNP
cord-298458-p7rvupjo	242	13	blockade	blockade	NN
cord-298458-p7rvupjo	242	14	resulted	result	VBD
cord-298458-p7rvupjo	242	15	in	in	IN
cord-298458-p7rvupjo	242	16	significantly	significantly	RB
cord-298458-p7rvupjo	242	17	increased	increase	VBN
cord-298458-p7rvupjo	242	18	CD8	CD8	NNP
cord-298458-p7rvupjo	242	19	T	T	NNP
cord-298458-p7rvupjo	242	20	cell	cell	NN
cord-298458-p7rvupjo	242	21	production	production	NN
cord-298458-p7rvupjo	242	22	of	of	IN
cord-298458-p7rvupjo	242	23	IFN	IFN	NNP
cord-298458-p7rvupjo	242	24	-	-	HYPH
cord-298458-p7rvupjo	242	25	γ	γ	NNP
cord-298458-p7rvupjo	242	26	,	,	,
cord-298458-p7rvupjo	242	27	IL-2	IL-2	NNP
cord-298458-p7rvupjo	242	28	,	,	,
cord-298458-p7rvupjo	242	29	and	and	CC
cord-298458-p7rvupjo	242	30	granzyme	granzyme	NNP
cord-298458-p7rvupjo	242	31	B	B	NNP
cord-298458-p7rvupjo	242	32	following	follow	VBG
cord-298458-p7rvupjo	242	33	RSV	RSV	NNP
cord-298458-p7rvupjo	242	34	infection	infection	NN
cord-298458-p7rvupjo	242	35	(	(	-LRB-
cord-298458-p7rvupjo	242	36	139	139	CD
cord-298458-p7rvupjo	242	37	)	)	-RRB-
cord-298458-p7rvupjo	242	38	.	.	.
cord-298458-p7rvupjo	243	1	Together	together	RB
cord-298458-p7rvupjo	243	2	,	,	,
cord-298458-p7rvupjo	243	3	these	these	DT
cord-298458-p7rvupjo	243	4	studies	study	NNS
cord-298458-p7rvupjo	243	5	demonstrate	demonstrate	VBP
cord-298458-p7rvupjo	243	6	a	a	DT
cord-298458-p7rvupjo	243	7	critical	critical	JJ
cord-298458-p7rvupjo	243	8	role	role	NN
cord-298458-p7rvupjo	243	9	for	for	IN
cord-298458-p7rvupjo	243	10	PD-1	PD-1	NNP
cord-298458-p7rvupjo	243	11	in	in	IN
cord-298458-p7rvupjo	243	12	the	the	DT
cord-298458-p7rvupjo	243	13	suppression	suppression	NN
cord-298458-p7rvupjo	243	14	of	of	IN
cord-298458-p7rvupjo	243	15	CD8	CD8	NNP
cord-298458-p7rvupjo	243	16	T	T	NNP
cord-298458-p7rvupjo	243	17	cell	cell	NN
cord-298458-p7rvupjo	243	18	-	-	HYPH
cord-298458-p7rvupjo	243	19	mediated	mediate	VBN
cord-298458-p7rvupjo	243	20	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	243	21	and	and	CC
cord-298458-p7rvupjo	243	22	cytokine	cytokine	NN
cord-298458-p7rvupjo	243	23	production	production	NN
cord-298458-p7rvupjo	243	24	in	in	IN
cord-298458-p7rvupjo	243	25	both	both	DT
cord-298458-p7rvupjo	243	26	mice	mouse	NNS
cord-298458-p7rvupjo	243	27	and	and	CC
cord-298458-p7rvupjo	243	28	humans	human	NNS
cord-298458-p7rvupjo	243	29	.	.	.
cord-298458-p7rvupjo	244	1	In	in	IN
cord-298458-p7rvupjo	244	2	the	the	DT
cord-298458-p7rvupjo	244	3	absence	absence	NN
cord-298458-p7rvupjo	244	4	of	of	IN
cord-298458-p7rvupjo	244	5	PD-1	PD-1	NNP
cord-298458-p7rvupjo	244	6	signaling	signal	VBG
cord-298458-p7rvupjo	244	7	following	follow	VBG
cord-298458-p7rvupjo	244	8	HMPV	hmpv	NN
cord-298458-p7rvupjo	244	9	infection	infection	NN
cord-298458-p7rvupjo	244	10	,	,	,
cord-298458-p7rvupjo	244	11	CD8	CD8	NNP
cord-298458-p7rvupjo	244	12	T	T	NNP
cord-298458-p7rvupjo	244	13	cell	cell	NN
cord-298458-p7rvupjo	244	14	IFNγ	IFNγ	NNS
cord-298458-p7rvupjo	244	15	production	production	NN
cord-298458-p7rvupjo	244	16	remains	remain	VBZ
cord-298458-p7rvupjo	244	17	impaired	impair	VBN
cord-298458-p7rvupjo	244	18	,	,	,
cord-298458-p7rvupjo	244	19	suggesting	suggest	VBG
cord-298458-p7rvupjo	244	20	the	the	DT
cord-298458-p7rvupjo	244	21	involvement	involvement	NN
cord-298458-p7rvupjo	244	22	of	of	IN
cord-298458-p7rvupjo	244	23	compensatory	compensatory	JJ
cord-298458-p7rvupjo	244	24	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	244	25	pathways	pathway	NNS
cord-298458-p7rvupjo	244	26	(	(	-LRB-
cord-298458-p7rvupjo	244	27	140	140	CD
cord-298458-p7rvupjo	244	28	)	)	-RRB-
cord-298458-p7rvupjo	244	29	.	.	.
cord-298458-p7rvupjo	245	1	Antigen	antigen	NN
cord-298458-p7rvupjo	245	2	-	-	HYPH
cord-298458-p7rvupjo	245	3	specific	specific	JJ
cord-298458-p7rvupjo	245	4	lung	lung	NN
cord-298458-p7rvupjo	245	5	CD8	CD8	NNP
cord-298458-p7rvupjo	245	6	T	T	NNP
cord-298458-p7rvupjo	245	7	cells	cell	NNS
cord-298458-p7rvupjo	245	8	express	express	VBP
cord-298458-p7rvupjo	245	9	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	245	10	receptors	receptor	NNS
cord-298458-p7rvupjo	245	11	Tim-3	Tim-3	NNP
cord-298458-p7rvupjo	245	12	,	,	,
cord-298458-p7rvupjo	245	13	LAG-3	LAG-3	NNP
cord-298458-p7rvupjo	245	14	,	,	,
cord-298458-p7rvupjo	245	15	and	and	CC
cord-298458-p7rvupjo	245	16	2B4	2b4	CD
cord-298458-p7rvupjo	245	17	following	follow	VBG
cord-298458-p7rvupjo	245	18	HMPV	hmpv	NN
cord-298458-p7rvupjo	245	19	infection	infection	NN
cord-298458-p7rvupjo	245	20	and	and	CC
cord-298458-p7rvupjo	245	21	exhibit	exhibit	NN
cord-298458-p7rvupjo	245	22	enhanced	enhance	VBN
cord-298458-p7rvupjo	245	23	cytokine	cytokine	NN
cord-298458-p7rvupjo	245	24	production	production	NN
cord-298458-p7rvupjo	245	25	following	follow	VBG
cord-298458-p7rvupjo	245	26	in	in	IN
cord-298458-p7rvupjo	245	27	vitro	vitro	FW
cord-298458-p7rvupjo	245	28	blockade	blockade	NN
cord-298458-p7rvupjo	245	29	of	of	IN
cord-298458-p7rvupjo	245	30	each	each	DT
cord-298458-p7rvupjo	245	31	receptor	receptor	NN
cord-298458-p7rvupjo	245	32	individually	individually	RB
cord-298458-p7rvupjo	245	33	(	(	-LRB-
cord-298458-p7rvupjo	245	34	140	140	CD
cord-298458-p7rvupjo	245	35	)	)	-RRB-
cord-298458-p7rvupjo	245	36	.	.	.
cord-298458-p7rvupjo	246	1	In	in	IN
cord-298458-p7rvupjo	246	2	vivo	vivo	NN
cord-298458-p7rvupjo	246	3	blockade	blockade	NN
cord-298458-p7rvupjo	246	4	of	of	IN
cord-298458-p7rvupjo	246	5	LAG-3	LAG-3	NNP
cord-298458-p7rvupjo	246	6	partially	partially	RB
cord-298458-p7rvupjo	246	7	restored	restore	VBD
cord-298458-p7rvupjo	246	8	CD8	CD8	NNP
cord-298458-p7rvupjo	246	9	T	T	NNP
cord-298458-p7rvupjo	246	10	cell	cell	NN
cord-298458-p7rvupjo	246	11	IFN	IFN	NNP
cord-298458-p7rvupjo	246	12	-	-	HYPH
cord-298458-p7rvupjo	246	13	γ	γ	NN
cord-298458-p7rvupjo	246	14	production	production	NN
cord-298458-p7rvupjo	246	15	in	in	IN
cord-298458-p7rvupjo	246	16	PD-1-deficient	pd-1-deficient	CD
cord-298458-p7rvupjo	246	17	mice	mouse	NNS
cord-298458-p7rvupjo	246	18	following	follow	VBG
cord-298458-p7rvupjo	246	19	HMPV	hmpv	NN
cord-298458-p7rvupjo	246	20	infection	infection	NN
cord-298458-p7rvupjo	246	21	(	(	-LRB-
cord-298458-p7rvupjo	246	22	140	140	CD
cord-298458-p7rvupjo	246	23	)	)	-RRB-
cord-298458-p7rvupjo	246	24	.	.	.
cord-298458-p7rvupjo	247	1	Tim-3	Tim-3	NNP
cord-298458-p7rvupjo	247	2	has	have	VBZ
cord-298458-p7rvupjo	247	3	also	also	RB
cord-298458-p7rvupjo	247	4	been	be	VBN
cord-298458-p7rvupjo	247	5	demonstrated	demonstrate	VBN
cord-298458-p7rvupjo	247	6	to	to	TO
cord-298458-p7rvupjo	247	7	be	be	VB
cord-298458-p7rvupjo	247	8	critical	critical	JJ
cord-298458-p7rvupjo	247	9	in	in	IN
cord-298458-p7rvupjo	247	10	suppressing	suppress	VBG
cord-298458-p7rvupjo	247	11	CD8	CD8	NNP
cord-298458-p7rvupjo	247	12	T	T	NNP
cord-298458-p7rvupjo	247	13	cell	cell	NN
cord-298458-p7rvupjo	247	14	responses	response	NNS
cord-298458-p7rvupjo	247	15	in	in	IN
cord-298458-p7rvupjo	247	16	vivo	vivo	NN
cord-298458-p7rvupjo	247	17	,	,	,
cord-298458-p7rvupjo	247	18	as	as	IN
cord-298458-p7rvupjo	247	19	Tim-3	Tim-3	NNP
cord-298458-p7rvupjo	247	20	receptor	receptor	NN
cord-298458-p7rvupjo	247	21	(	(	-LRB-
cord-298458-p7rvupjo	247	22	Galectin-9)-deficient	Galectin-9)-deficient	NNP
cord-298458-p7rvupjo	247	23	mice	mouse	NNS
cord-298458-p7rvupjo	247	24	exhibited	exhibit	VBD
cord-298458-p7rvupjo	247	25	significantly	significantly	RB
cord-298458-p7rvupjo	247	26	enhanced	enhance	VBN
cord-298458-p7rvupjo	247	27	CD8	CD8	NNP
cord-298458-p7rvupjo	247	28	T	T	NNP
cord-298458-p7rvupjo	247	29	cell	cell	NN
cord-298458-p7rvupjo	247	30	responses	response	NNS
cord-298458-p7rvupjo	247	31	following	follow	VBG
cord-298458-p7rvupjo	247	32	both	both	CC
cord-298458-p7rvupjo	247	33	primary	primary	JJ
cord-298458-p7rvupjo	247	34	and	and	CC
cord-298458-p7rvupjo	247	35	secondary	secondary	JJ
cord-298458-p7rvupjo	247	36	IAV	IAV	NNP
cord-298458-p7rvupjo	247	37	infections	infection	NNS
cord-298458-p7rvupjo	247	38	(	(	-LRB-
cord-298458-p7rvupjo	247	39	141	141	CD
cord-298458-p7rvupjo	247	40	)	)	-RRB-
cord-298458-p7rvupjo	247	41	.	.	.
cord-298458-p7rvupjo	248	1	Together	together	RB
cord-298458-p7rvupjo	248	2	,	,	,
cord-298458-p7rvupjo	248	3	these	these	DT
cord-298458-p7rvupjo	248	4	studies	study	NNS
cord-298458-p7rvupjo	248	5	indicate	indicate	VBP
cord-298458-p7rvupjo	248	6	that	that	IN
cord-298458-p7rvupjo	248	7	multiple	multiple	JJ
cord-298458-p7rvupjo	248	8	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	248	9	receptor	receptor	NN
cord-298458-p7rvupjo	248	10	pathways	pathway	NNS
cord-298458-p7rvupjo	248	11	are	be	VBP
cord-298458-p7rvupjo	248	12	utilized	utilize	VBN
cord-298458-p7rvupjo	248	13	following	follow	VBG
cord-298458-p7rvupjo	248	14	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	248	15	virus	virus	NN
cord-298458-p7rvupjo	248	16	infection	infection	NN
cord-298458-p7rvupjo	248	17	to	to	TO
cord-298458-p7rvupjo	248	18	dampen	dampen	VB
cord-298458-p7rvupjo	248	19	the	the	DT
cord-298458-p7rvupjo	248	20	pathogenic	pathogenic	JJ
cord-298458-p7rvupjo	248	21	CD8	CD8	NNP
cord-298458-p7rvupjo	248	22	T	T	NNP
cord-298458-p7rvupjo	248	23	cell	cell	NN
cord-298458-p7rvupjo	248	24	response	response	NN
cord-298458-p7rvupjo	248	25	and	and	CC
cord-298458-p7rvupjo	248	26	prevent	prevent	VB
cord-298458-p7rvupjo	248	27	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	248	28	.	.	.
cord-298458-p7rvupjo	249	1	Successful	successful	JJ
cord-298458-p7rvupjo	249	2	vaccinations	vaccination	NNS
cord-298458-p7rvupjo	249	3	against	against	IN
cord-298458-p7rvupjo	249	4	the	the	DT
cord-298458-p7rvupjo	249	5	majority	majority	NN
cord-298458-p7rvupjo	249	6	of	of	IN
cord-298458-p7rvupjo	249	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	249	8	viruses	virus	NNS
cord-298458-p7rvupjo	249	9	remain	remain	VBP
cord-298458-p7rvupjo	249	10	elusive	elusive	JJ
cord-298458-p7rvupjo	249	11	.	.	.
cord-298458-p7rvupjo	250	1	The	the	DT
cord-298458-p7rvupjo	250	2	goal	goal	NN
cord-298458-p7rvupjo	250	3	of	of	IN
cord-298458-p7rvupjo	250	4	most	most	JJS
cord-298458-p7rvupjo	250	5	vaccination	vaccination	NN
cord-298458-p7rvupjo	250	6	strategies	strategy	NNS
cord-298458-p7rvupjo	250	7	is	be	VBZ
cord-298458-p7rvupjo	250	8	to	to	TO
cord-298458-p7rvupjo	250	9	induce	induce	VB
cord-298458-p7rvupjo	250	10	robust	robust	JJ
cord-298458-p7rvupjo	250	11	virus	virus	NN
cord-298458-p7rvupjo	250	12	-	-	HYPH
cord-298458-p7rvupjo	250	13	specific	specific	JJ
cord-298458-p7rvupjo	250	14	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	250	15	antibody	antibody	NN
cord-298458-p7rvupjo	250	16	responses	response	NNS
cord-298458-p7rvupjo	250	17	.	.	.
cord-298458-p7rvupjo	251	1	However	however	RB
cord-298458-p7rvupjo	251	2	,	,	,
cord-298458-p7rvupjo	251	3	the	the	DT
cord-298458-p7rvupjo	251	4	antibody	antibody	NN
cord-298458-p7rvupjo	251	5	response	response	NN
cord-298458-p7rvupjo	251	6	generated	generate	VBN
cord-298458-p7rvupjo	251	7	by	by	IN
cord-298458-p7rvupjo	251	8	infection	infection	NN
cord-298458-p7rvupjo	251	9	with	with	IN
cord-298458-p7rvupjo	251	10	many	many	JJ
cord-298458-p7rvupjo	251	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	251	12	infections	infection	NNS
cord-298458-p7rvupjo	251	13	,	,	,
cord-298458-p7rvupjo	251	14	including	include	VBG
cord-298458-p7rvupjo	251	15	RSV	RSV	NNP
cord-298458-p7rvupjo	251	16	and	and	CC
cord-298458-p7rvupjo	251	17	RV	RV	NNP
cord-298458-p7rvupjo	251	18	,	,	,
cord-298458-p7rvupjo	251	19	wanes	wane	VBZ
cord-298458-p7rvupjo	251	20	over	over	IN
cord-298458-p7rvupjo	251	21	time	time	NN
cord-298458-p7rvupjo	251	22	.	.	.
cord-298458-p7rvupjo	252	1	Therefore	therefore	RB
cord-298458-p7rvupjo	252	2	,	,	,
cord-298458-p7rvupjo	252	3	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	252	4	antibody	antibody	NN
cord-298458-p7rvupjo	252	5	responses	response	NNS
cord-298458-p7rvupjo	252	6	as	as	IN
cord-298458-p7rvupjo	252	7	the	the	DT
cord-298458-p7rvupjo	252	8	sole	sole	JJ
cord-298458-p7rvupjo	252	9	mediator	mediator	NN
cord-298458-p7rvupjo	252	10	of	of	IN
cord-298458-p7rvupjo	252	11	a	a	DT
cord-298458-p7rvupjo	252	12	vaccine	vaccine	NN
cord-298458-p7rvupjo	252	13	against	against	IN
cord-298458-p7rvupjo	252	14	most	most	JJS
cord-298458-p7rvupjo	252	15	respiratory	respiratory	JJ
cord-298458-p7rvupjo	252	16	viruses	virus	NNS
cord-298458-p7rvupjo	252	17	may	may	MD
cord-298458-p7rvupjo	252	18	not	not	RB
cord-298458-p7rvupjo	252	19	provide	provide	VB
cord-298458-p7rvupjo	252	20	long	long	JJ
cord-298458-p7rvupjo	252	21	-	-	HYPH
cord-298458-p7rvupjo	252	22	term	term	NN
cord-298458-p7rvupjo	252	23	protection	protection	NN
cord-298458-p7rvupjo	252	24	without	without	IN
cord-298458-p7rvupjo	252	25	yearly	yearly	JJ
cord-298458-p7rvupjo	252	26	vaccination	vaccination	NN
cord-298458-p7rvupjo	252	27	.	.	.
cord-298458-p7rvupjo	253	1	Vaccination	vaccination	NN
cord-298458-p7rvupjo	253	2	strategies	strategy	NNS
cord-298458-p7rvupjo	253	3	that	that	WDT
cord-298458-p7rvupjo	253	4	include	include	VBP
cord-298458-p7rvupjo	253	5	the	the	DT
cord-298458-p7rvupjo	253	6	induction	induction	NN
cord-298458-p7rvupjo	253	7	of	of	IN
cord-298458-p7rvupjo	253	8	virus	virus	NN
cord-298458-p7rvupjo	253	9	-	-	HYPH
cord-298458-p7rvupjo	253	10	specific	specific	JJ
cord-298458-p7rvupjo	253	11	CD8	CD8	NNP
cord-298458-p7rvupjo	253	12	T	T	NNP
cord-298458-p7rvupjo	253	13	cell	cell	NN
cord-298458-p7rvupjo	253	14	responses	response	NNS
cord-298458-p7rvupjo	253	15	,	,	,
cord-298458-p7rvupjo	253	16	either	either	CC
cord-298458-p7rvupjo	253	17	alone	alone	RB
cord-298458-p7rvupjo	253	18	or	or	CC
cord-298458-p7rvupjo	253	19	in	in	IN
cord-298458-p7rvupjo	253	20	combination	combination	NN
cord-298458-p7rvupjo	253	21	with	with	IN
cord-298458-p7rvupjo	253	22	humoral	humoral	JJ
cord-298458-p7rvupjo	253	23	immunity	immunity	NN
cord-298458-p7rvupjo	253	24	,	,	,
cord-298458-p7rvupjo	253	25	may	may	MD
cord-298458-p7rvupjo	253	26	be	be	VB
cord-298458-p7rvupjo	253	27	advantageous	advantageous	JJ
cord-298458-p7rvupjo	253	28	by	by	IN
cord-298458-p7rvupjo	253	29	providing	provide	VBG
cord-298458-p7rvupjo	253	30	many	many	JJ
cord-298458-p7rvupjo	253	31	benefits	benefit	NNS
cord-298458-p7rvupjo	253	32	associated	associate	VBN
cord-298458-p7rvupjo	253	33	with	with	IN
cord-298458-p7rvupjo	253	34	cellular	cellular	JJ
cord-298458-p7rvupjo	253	35	immune	immune	JJ
cord-298458-p7rvupjo	253	36	responses	response	NNS
cord-298458-p7rvupjo	253	37	.	.	.
cord-298458-p7rvupjo	254	1	CD8	CD8	NNP
cord-298458-p7rvupjo	254	2	T	T	NNP
cord-298458-p7rvupjo	254	3	cells	cell	NNS
cord-298458-p7rvupjo	254	4	are	be	VBP
cord-298458-p7rvupjo	254	5	critical	critical	JJ
cord-298458-p7rvupjo	254	6	for	for	IN
cord-298458-p7rvupjo	254	7	the	the	DT
cord-298458-p7rvupjo	254	8	elimination	elimination	NN
cord-298458-p7rvupjo	254	9	of	of	IN
cord-298458-p7rvupjo	254	10	virusinfected	virusinfected	JJ
cord-298458-p7rvupjo	254	11	cells	cell	NNS
cord-298458-p7rvupjo	254	12	,	,	,
cord-298458-p7rvupjo	254	13	and	and	CC
cord-298458-p7rvupjo	254	14	viral	viral	JJ
cord-298458-p7rvupjo	254	15	clearance	clearance	NN
cord-298458-p7rvupjo	254	16	was	be	VBD
cord-298458-p7rvupjo	254	17	prolonged	prolong	VBN
cord-298458-p7rvupjo	254	18	in	in	IN
cord-298458-p7rvupjo	254	19	the	the	DT
cord-298458-p7rvupjo	254	20	absence	absence	NN
cord-298458-p7rvupjo	254	21	of	of	IN
cord-298458-p7rvupjo	254	22	CD8	CD8	NNP
cord-298458-p7rvupjo	254	23	T	T	NNP
cord-298458-p7rvupjo	254	24	cells	cell	NNS
cord-298458-p7rvupjo	254	25	following	follow	VBG
cord-298458-p7rvupjo	254	26	acute	acute	JJ
cord-298458-p7rvupjo	254	27	respiratory	respiratory	JJ
cord-298458-p7rvupjo	254	28	virus	virus	NN
cord-298458-p7rvupjo	254	29	infections	infection	NNS
cord-298458-p7rvupjo	254	30	.	.	.
cord-298458-p7rvupjo	255	1	Additionally	additionally	RB
cord-298458-p7rvupjo	255	2	,	,	,
cord-298458-p7rvupjo	255	3	robust	robust	JJ
cord-298458-p7rvupjo	255	4	memory	memory	NN
cord-298458-p7rvupjo	255	5	CD8	CD8	NNP
cord-298458-p7rvupjo	255	6	T	T	NNP
cord-298458-p7rvupjo	255	7	cell	cell	NN
cord-298458-p7rvupjo	255	8	responses	response	NNS
cord-298458-p7rvupjo	255	9	efficiently	efficiently	RB
cord-298458-p7rvupjo	255	10	reduced	reduce	VBN
cord-298458-p7rvupjo	255	11	lung	lung	NN
cord-298458-p7rvupjo	255	12	viral	viral	JJ
cord-298458-p7rvupjo	255	13	titers	titer	NNS
cord-298458-p7rvupjo	255	14	in	in	IN
cord-298458-p7rvupjo	255	15	the	the	DT
cord-298458-p7rvupjo	255	16	absence	absence	NN
cord-298458-p7rvupjo	255	17	of	of	IN
cord-298458-p7rvupjo	255	18	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	255	19	antibodies	antibody	NNS
cord-298458-p7rvupjo	255	20	following	follow	VBG
cord-298458-p7rvupjo	255	21	RSV	RSV	NNP
cord-298458-p7rvupjo	255	22	,	,	,
cord-298458-p7rvupjo	255	23	IAV	IAV	NNP
cord-298458-p7rvupjo	255	24	,	,	,
cord-298458-p7rvupjo	255	25	or	or	CC
cord-298458-p7rvupjo	255	26	SARS	SARS	NNP
cord-298458-p7rvupjo	255	27	secondary	secondary	JJ
cord-298458-p7rvupjo	255	28	infections	infection	NNS
cord-298458-p7rvupjo	255	29	.	.	.
cord-298458-p7rvupjo	256	1	An	an	DT
cord-298458-p7rvupjo	256	2	important	important	JJ
cord-298458-p7rvupjo	256	3	property	property	NN
cord-298458-p7rvupjo	256	4	of	of	IN
cord-298458-p7rvupjo	256	5	CD8	CD8	NNP
cord-298458-p7rvupjo	256	6	T	T	NNP
cord-298458-p7rvupjo	256	7	cells	cell	NNS
cord-298458-p7rvupjo	256	8	is	be	VBZ
cord-298458-p7rvupjo	256	9	that	that	IN
cord-298458-p7rvupjo	256	10	they	-PRON-	PRP
cord-298458-p7rvupjo	256	11	often	often	RB
cord-298458-p7rvupjo	256	12	recognize	recognize	VBP
cord-298458-p7rvupjo	256	13	conserved	conserve	VBN
cord-298458-p7rvupjo	256	14	viral	viral	JJ
cord-298458-p7rvupjo	256	15	proteins	protein	NNS
cord-298458-p7rvupjo	256	16	,	,	,
cord-298458-p7rvupjo	256	17	allowing	allow	VBG
cord-298458-p7rvupjo	256	18	for	for	IN
cord-298458-p7rvupjo	256	19	cross	cross	NN
cord-298458-p7rvupjo	256	20	-	-	NN
cord-298458-p7rvupjo	256	21	protection	protection	NN
cord-298458-p7rvupjo	256	22	between	between	IN
cord-298458-p7rvupjo	256	23	different	different	JJ
cord-298458-p7rvupjo	256	24	virus	virus	NN
cord-298458-p7rvupjo	256	25	strains	strain	NNS
cord-298458-p7rvupjo	256	26	.	.	.
cord-298458-p7rvupjo	257	1	This	this	DT
cord-298458-p7rvupjo	257	2	is	be	VBZ
cord-298458-p7rvupjo	257	3	particularly	particularly	RB
cord-298458-p7rvupjo	257	4	important	important	JJ
cord-298458-p7rvupjo	257	5	for	for	IN
cord-298458-p7rvupjo	257	6	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	257	7	protection	protection	NN
cord-298458-p7rvupjo	257	8	of	of	IN
cord-298458-p7rvupjo	257	9	IAV	IAV	NNP
cord-298458-p7rvupjo	257	10	strains	strain	NNS
cord-298458-p7rvupjo	257	11	,	,	,
cord-298458-p7rvupjo	257	12	as	as	IN
cord-298458-p7rvupjo	257	13	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	257	14	antibodies	antibody	NNS
cord-298458-p7rvupjo	257	15	are	be	VBP
cord-298458-p7rvupjo	257	16	not	not	RB
cord-298458-p7rvupjo	257	17	capable	capable	JJ
cord-298458-p7rvupjo	257	18	of	of	IN
cord-298458-p7rvupjo	257	19	recognizing	recognize	VBG
cord-298458-p7rvupjo	257	20	IAV	IAV	NNP
cord-298458-p7rvupjo	257	21	strains	strain	NNS
cord-298458-p7rvupjo	257	22	of	of	IN
cord-298458-p7rvupjo	257	23	differing	differ	VBG
cord-298458-p7rvupjo	257	24	subtypes	subtype	NNS
cord-298458-p7rvupjo	257	25	.	.	.
cord-298458-p7rvupjo	258	1	Despite	despite	IN
cord-298458-p7rvupjo	258	2	their	-PRON-	PRP$
cord-298458-p7rvupjo	258	3	benefits	benefit	NNS
cord-298458-p7rvupjo	258	4	in	in	IN
cord-298458-p7rvupjo	258	5	mediating	mediate	VBG
cord-298458-p7rvupjo	258	6	viral	viral	JJ
cord-298458-p7rvupjo	258	7	clearance	clearance	NN
cord-298458-p7rvupjo	258	8	and	and	CC
cord-298458-p7rvupjo	258	9	providing	provide	VBG
cord-298458-p7rvupjo	258	10	protection	protection	NN
cord-298458-p7rvupjo	258	11	against	against	IN
cord-298458-p7rvupjo	258	12	secondary	secondary	JJ
cord-298458-p7rvupjo	258	13	infections	infection	NNS
cord-298458-p7rvupjo	258	14	,	,	,
cord-298458-p7rvupjo	258	15	memory	memory	NN
cord-298458-p7rvupjo	258	16	CD8	CD8	NNP
cord-298458-p7rvupjo	258	17	T	T	NNP
cord-298458-p7rvupjo	258	18	cell	cell	NN
cord-298458-p7rvupjo	258	19	responses	response	NNS
cord-298458-p7rvupjo	258	20	have	have	VBP
cord-298458-p7rvupjo	258	21	been	be	VBN
cord-298458-p7rvupjo	258	22	associated	associate	VBN
cord-298458-p7rvupjo	258	23	with	with	IN
cord-298458-p7rvupjo	258	24	the	the	DT
cord-298458-p7rvupjo	258	25	induction	induction	NN
cord-298458-p7rvupjo	258	26	of	of	IN
cord-298458-p7rvupjo	258	27	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	258	28	following	follow	VBG
cord-298458-p7rvupjo	258	29	respiratory	respiratory	JJ
cord-298458-p7rvupjo	258	30	virus	virus	NN
cord-298458-p7rvupjo	258	31	infections	infection	NNS
cord-298458-p7rvupjo	258	32	.	.	.
cord-298458-p7rvupjo	259	1	The	the	DT
cord-298458-p7rvupjo	259	2	same	same	JJ
cord-298458-p7rvupjo	259	3	antiviral	antiviral	JJ
cord-298458-p7rvupjo	259	4	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	259	5	employed	employ	VBN
cord-298458-p7rvupjo	259	6	by	by	IN
cord-298458-p7rvupjo	259	7	memory	memory	NN
cord-298458-p7rvupjo	259	8	CD8	CD8	NNP
cord-298458-p7rvupjo	259	9	T	T	NNP
cord-298458-p7rvupjo	259	10	cells	cell	NNS
cord-298458-p7rvupjo	259	11	to	to	TO
cord-298458-p7rvupjo	259	12	accelerate	accelerate	VB
cord-298458-p7rvupjo	259	13	viral	viral	JJ
cord-298458-p7rvupjo	259	14	clearance	clearance	NN
cord-298458-p7rvupjo	259	15	also	also	RB
cord-298458-p7rvupjo	259	16	contribute	contribute	VBP
cord-298458-p7rvupjo	259	17	to	to	IN
cord-298458-p7rvupjo	259	18	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	259	19	,	,	,
cord-298458-p7rvupjo	259	20	including	include	VBG
cord-298458-p7rvupjo	259	21	the	the	DT
cord-298458-p7rvupjo	259	22	Fas	Fas	NNP
cord-298458-p7rvupjo	259	23	/	/	SYM
cord-298458-p7rvupjo	259	24	FasL	FasL	NNP
cord-298458-p7rvupjo	259	25	pathway	pathway	NN
cord-298458-p7rvupjo	259	26	-	-	HYPH
cord-298458-p7rvupjo	259	27	and	and	CC
cord-298458-p7rvupjo	259	28	perforin	perforin	NN
cord-298458-p7rvupjo	259	29	-	-	HYPH
cord-298458-p7rvupjo	259	30	mediated	mediate	VBN
cord-298458-p7rvupjo	259	31	cytolysis	cytolysis	NN
cord-298458-p7rvupjo	259	32	and	and	CC
cord-298458-p7rvupjo	259	33	IFN	IFN	NNP
cord-298458-p7rvupjo	259	34	-	-	HYPH
cord-298458-p7rvupjo	259	35	γ	γ	NNP
cord-298458-p7rvupjo	259	36	and	and	CC
cord-298458-p7rvupjo	259	37	TNF	TNF	NNP
cord-298458-p7rvupjo	259	38	cytokine	cytokine	NN
cord-298458-p7rvupjo	259	39	secretion	secretion	NN
cord-298458-p7rvupjo	259	40	.	.	.
cord-298458-p7rvupjo	260	1	Thus	thus	RB
cord-298458-p7rvupjo	260	2	,	,	,
cord-298458-p7rvupjo	260	3	the	the	DT
cord-298458-p7rvupjo	260	4	efficient	efficient	JJ
cord-298458-p7rvupjo	260	5	elimination	elimination	NN
cord-298458-p7rvupjo	260	6	of	of	IN
cord-298458-p7rvupjo	260	7	respiratory	respiratory	JJ
cord-298458-p7rvupjo	260	8	viruses	virus	NNS
cord-298458-p7rvupjo	260	9	by	by	IN
cord-298458-p7rvupjo	260	10	memory	memory	NN
cord-298458-p7rvupjo	260	11	CD8	CD8	NNP
cord-298458-p7rvupjo	260	12	T	T	NNP
cord-298458-p7rvupjo	260	13	cells	cell	NNS
cord-298458-p7rvupjo	260	14	comes	come	VBZ
cord-298458-p7rvupjo	260	15	at	at	IN
cord-298458-p7rvupjo	260	16	a	a	DT
cord-298458-p7rvupjo	260	17	cost	cost	NN
cord-298458-p7rvupjo	260	18	of	of	IN
cord-298458-p7rvupjo	260	19	disease	disease	NN
cord-298458-p7rvupjo	260	20	for	for	IN
cord-298458-p7rvupjo	260	21	the	the	DT
cord-298458-p7rvupjo	260	22	host	host	NN
cord-298458-p7rvupjo	260	23	.	.	.
cord-298458-p7rvupjo	261	1	CD8	CD8	NNP
cord-298458-p7rvupjo	261	2	T	T	NNP
cord-298458-p7rvupjo	261	3	cell	cell	NN
cord-298458-p7rvupjo	261	4	-	-	HYPH
cord-298458-p7rvupjo	261	5	mediated	mediate	VBN
cord-298458-p7rvupjo	261	6	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	261	7	appears	appear	VBZ
cord-298458-p7rvupjo	261	8	to	to	TO
cord-298458-p7rvupjo	261	9	be	be	VB
cord-298458-p7rvupjo	261	10	virus	virus	NN
cord-298458-p7rvupjo	261	11	-	-	HYPH
cord-298458-p7rvupjo	261	12	specific	specific	JJ
cord-298458-p7rvupjo	261	13	.	.	.
cord-298458-p7rvupjo	262	1	Although	although	IN
cord-298458-p7rvupjo	262	2	high	high	JJ
cord-298458-p7rvupjo	262	3	frequency	frequency	NN
cord-298458-p7rvupjo	262	4	,	,	,
cord-298458-p7rvupjo	262	5	systemic	systemic	JJ
cord-298458-p7rvupjo	262	6	,	,	,
cord-298458-p7rvupjo	262	7	antigen	antigen	NN
cord-298458-p7rvupjo	262	8	-	-	HYPH
cord-298458-p7rvupjo	262	9	specific	specific	JJ
cord-298458-p7rvupjo	262	10	memory	memory	NN
cord-298458-p7rvupjo	262	11	CD8	CD8	NNP
cord-298458-p7rvupjo	262	12	T	T	NNP
cord-298458-p7rvupjo	262	13	cells	cell	NNS
cord-298458-p7rvupjo	262	14	induced	induce	VBN
cord-298458-p7rvupjo	262	15	severe	severe	JJ
cord-298458-p7rvupjo	262	16	disease	disease	NN
cord-298458-p7rvupjo	262	17	and	and	CC
cord-298458-p7rvupjo	262	18	mortality	mortality	NN
cord-298458-p7rvupjo	262	19	following	follow	VBG
cord-298458-p7rvupjo	262	20	RSV	RSV	NNP
cord-298458-p7rvupjo	262	21	infection	infection	NN
cord-298458-p7rvupjo	262	22	,	,	,
cord-298458-p7rvupjo	262	23	no	no	DT
cord-298458-p7rvupjo	262	24	pathology	pathology	NN
cord-298458-p7rvupjo	262	25	was	be	VBD
cord-298458-p7rvupjo	262	26	observed	observe	VBN
cord-298458-p7rvupjo	262	27	using	use	VBG
cord-298458-p7rvupjo	262	28	similar	similar	JJ
cord-298458-p7rvupjo	262	29	systems	system	NNS
cord-298458-p7rvupjo	262	30	for	for	IN
cord-298458-p7rvupjo	262	31	IAV	IAV	NNP
cord-298458-p7rvupjo	262	32	and	and	CC
cord-298458-p7rvupjo	262	33	SARS	SARS	NNP
cord-298458-p7rvupjo	262	34	infections	infection	NNS
cord-298458-p7rvupjo	262	35	.	.	.
cord-298458-p7rvupjo	263	1	Therefore	therefore	RB
cord-298458-p7rvupjo	263	2	,	,	,
cord-298458-p7rvupjo	263	3	induction	induction	NN
cord-298458-p7rvupjo	263	4	of	of	IN
cord-298458-p7rvupjo	263	5	memory	memory	NN
cord-298458-p7rvupjo	263	6	CD8	CD8	NNP
cord-298458-p7rvupjo	263	7	T	T	NNP
cord-298458-p7rvupjo	263	8	cells	cell	NNS
cord-298458-p7rvupjo	263	9	as	as	IN
cord-298458-p7rvupjo	263	10	the	the	DT
cord-298458-p7rvupjo	263	11	sole	sole	JJ
cord-298458-p7rvupjo	263	12	immune	immune	JJ
cord-298458-p7rvupjo	263	13	mediator	mediator	NN
cord-298458-p7rvupjo	263	14	may	may	MD
cord-298458-p7rvupjo	263	15	be	be	VB
cord-298458-p7rvupjo	263	16	particularly	particularly	RB
cord-298458-p7rvupjo	263	17	dangerous	dangerous	JJ
cord-298458-p7rvupjo	263	18	for	for	IN
cord-298458-p7rvupjo	263	19	an	an	DT
cord-298458-p7rvupjo	263	20	RSV	RSV	NNP
cord-298458-p7rvupjo	263	21	vaccine	vaccine	NN
cord-298458-p7rvupjo	263	22	,	,	,
cord-298458-p7rvupjo	263	23	but	but	CC
cord-298458-p7rvupjo	263	24	significantly	significantly	RB
cord-298458-p7rvupjo	263	25	less	less	RBR
cord-298458-p7rvupjo	263	26	so	so	RB
cord-298458-p7rvupjo	263	27	in	in	IN
cord-298458-p7rvupjo	263	28	either	either	CC
cord-298458-p7rvupjo	263	29	an	an	DT
cord-298458-p7rvupjo	263	30	IAV	IAV	NNP
cord-298458-p7rvupjo	263	31	or	or	CC
cord-298458-p7rvupjo	263	32	a	a	DT
cord-298458-p7rvupjo	263	33	SARS	SARS	NNP
cord-298458-p7rvupjo	263	34	vaccine	vaccine	NN
cord-298458-p7rvupjo	263	35	.	.	.
cord-298458-p7rvupjo	264	1	To	to	TO
cord-298458-p7rvupjo	264	2	be	be	VB
cord-298458-p7rvupjo	264	3	able	able	JJ
cord-298458-p7rvupjo	264	4	to	to	TO
cord-298458-p7rvupjo	264	5	include	include	VB
cord-298458-p7rvupjo	264	6	CD8	CD8	NNP
cord-298458-p7rvupjo	264	7	T	T	NNP
cord-298458-p7rvupjo	264	8	cell	cell	NN
cord-298458-p7rvupjo	264	9	responses	response	NNS
cord-298458-p7rvupjo	264	10	within	within	IN
cord-298458-p7rvupjo	264	11	a	a	DT
cord-298458-p7rvupjo	264	12	future	future	JJ
cord-298458-p7rvupjo	264	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	264	14	virus	virus	NN
cord-298458-p7rvupjo	264	15	vaccine	vaccine	NN
cord-298458-p7rvupjo	264	16	,	,	,
cord-298458-p7rvupjo	264	17	it	-PRON-	PRP
cord-298458-p7rvupjo	264	18	will	will	MD
cord-298458-p7rvupjo	264	19	be	be	VB
cord-298458-p7rvupjo	264	20	extremely	extremely	RB
cord-298458-p7rvupjo	264	21	important	important	JJ
cord-298458-p7rvupjo	264	22	to	to	TO
cord-298458-p7rvupjo	264	23	determine	determine	VB
cord-298458-p7rvupjo	264	24	how	how	WRB
cord-298458-p7rvupjo	264	25	to	to	TO
cord-298458-p7rvupjo	264	26	balance	balance	VB
cord-298458-p7rvupjo	264	27	CD8	CD8	NNP
cord-298458-p7rvupjo	264	28	T	T	NNP
cord-298458-p7rvupjo	264	29	cell	cell	NN
cord-298458-p7rvupjo	264	30	-	-	HYPH
cord-298458-p7rvupjo	264	31	mediated	mediate	VBN
cord-298458-p7rvupjo	264	32	protection	protection	NN
cord-298458-p7rvupjo	264	33	versus	versus	IN
cord-298458-p7rvupjo	264	34	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	264	35	following	follow	VBG
cord-298458-p7rvupjo	264	36	respiratory	respiratory	JJ
cord-298458-p7rvupjo	264	37	infection	infection	NN
cord-298458-p7rvupjo	264	38	.	.	.
cord-298458-p7rvupjo	265	1	For	for	IN
cord-298458-p7rvupjo	265	2	RSV	RSV	NNP
cord-298458-p7rvupjo	265	3	in	in	IN
cord-298458-p7rvupjo	265	4	particular	particular	JJ
cord-298458-p7rvupjo	265	5	,	,	,
cord-298458-p7rvupjo	265	6	three	three	CD
cord-298458-p7rvupjo	265	7	critical	critical	JJ
cord-298458-p7rvupjo	265	8	aspects	aspect	NNS
cord-298458-p7rvupjo	265	9	to	to	TO
cord-298458-p7rvupjo	265	10	consider	consider	VB
cord-298458-p7rvupjo	265	11	in	in	IN
cord-298458-p7rvupjo	265	12	this	this	DT
cord-298458-p7rvupjo	265	13	balance	balance	NN
cord-298458-p7rvupjo	265	14	include	include	VBP
cord-298458-p7rvupjo	265	15	magnitude	magnitude	NN
cord-298458-p7rvupjo	265	16	,	,	,
cord-298458-p7rvupjo	265	17	localization	localization	NN
cord-298458-p7rvupjo	265	18	,	,	,
cord-298458-p7rvupjo	265	19	and	and	CC
cord-298458-p7rvupjo	265	20	regulation	regulation	NN
cord-298458-p7rvupjo	265	21	of	of	IN
cord-298458-p7rvupjo	265	22	the	the	DT
cord-298458-p7rvupjo	265	23	RSV	RSV	NNP
cord-298458-p7rvupjo	265	24	-	-	HYPH
cord-298458-p7rvupjo	265	25	specific	specific	JJ
cord-298458-p7rvupjo	265	26	CD8	CD8	NNP
cord-298458-p7rvupjo	265	27	T	T	NNP
cord-298458-p7rvupjo	265	28	cell	cell	NN
cord-298458-p7rvupjo	265	29	response	response	NN
cord-298458-p7rvupjo	265	30	(	(	-LRB-
cord-298458-p7rvupjo	265	31	Figure	figure	NN
cord-298458-p7rvupjo	265	32	1	1	CD
cord-298458-p7rvupjo	265	33	)	)	-RRB-
cord-298458-p7rvupjo	265	34	.	.	.
cord-298458-p7rvupjo	266	1	DC	DC	NNP
cord-298458-p7rvupjo	266	2	-	-	HYPH
cord-298458-p7rvupjo	266	3	LM	LM	NNP
cord-298458-p7rvupjo	266	4	immunization	immunization	NN
cord-298458-p7rvupjo	266	5	generated	generate	VBD
cord-298458-p7rvupjo	266	6	M282	M282	NNP
cord-298458-p7rvupjo	266	7	-	-	HYPH
cord-298458-p7rvupjo	266	8	90-specific	90-specific	CD
cord-298458-p7rvupjo	266	9	CD8	CD8	NNP
cord-298458-p7rvupjo	266	10	T	T	NNP
cord-298458-p7rvupjo	266	11	cells	cell	NNS
cord-298458-p7rvupjo	266	12	at	at	IN
cord-298458-p7rvupjo	266	13	a	a	DT
cord-298458-p7rvupjo	266	14	frequency	frequency	NN
cord-298458-p7rvupjo	266	15	of	of	IN
cord-298458-p7rvupjo	266	16	approximately	approximately	RB
cord-298458-p7rvupjo	266	17	20	20	CD
cord-298458-p7rvupjo	266	18	%	%	NN
cord-298458-p7rvupjo	266	19	in	in	IN
cord-298458-p7rvupjo	266	20	the	the	DT
cord-298458-p7rvupjo	266	21	peripheral	peripheral	JJ
cord-298458-p7rvupjo	266	22	blood	blood	NN
cord-298458-p7rvupjo	266	23	,	,	,
cord-298458-p7rvupjo	266	24	but	but	CC
cord-298458-p7rvupjo	266	25	induced	induce	VBN
cord-298458-p7rvupjo	266	26	fatal	fatal	JJ
cord-298458-p7rvupjo	266	27	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	266	28	following	follow	VBG
cord-298458-p7rvupjo	266	29	RSV	RSV	NNP
cord-298458-p7rvupjo	266	30	challenge	challenge	NN
cord-298458-p7rvupjo	266	31	(	(	-LRB-
cord-298458-p7rvupjo	266	32	30	30	CD
cord-298458-p7rvupjo	266	33	)	)	-RRB-
cord-298458-p7rvupjo	266	34	.	.	.
cord-298458-p7rvupjo	267	1	However	however	RB
cord-298458-p7rvupjo	267	2	,	,	,
cord-298458-p7rvupjo	267	3	DC	DC	NNP
cord-298458-p7rvupjo	267	4	-	-	HYPH
cord-298458-p7rvupjo	267	5	prime	prime	NN
cord-298458-p7rvupjo	267	6	only	only	RB
cord-298458-p7rvupjo	267	7	and	and	CC
cord-298458-p7rvupjo	267	8	TriVax	TriVax	NNP
cord-298458-p7rvupjo	267	9	immunizations	immunization	NNS
cord-298458-p7rvupjo	267	10	generated	generate	VBD
cord-298458-p7rvupjo	267	11	a	a	DT
cord-298458-p7rvupjo	267	12	much	much	RB
cord-298458-p7rvupjo	267	13	lower	low	JJR
cord-298458-p7rvupjo	267	14	frequency	frequency	NN
cord-298458-p7rvupjo	267	15	of	of	IN
cord-298458-p7rvupjo	267	16	total	total	JJ
cord-298458-p7rvupjo	267	17	M282-specific	m282-specific	JJ
cord-298458-p7rvupjo	267	18	CD8	CD8	NNP
cord-298458-p7rvupjo	267	19	T	T	NNP
cord-298458-p7rvupjo	267	20	cells	cell	NNS
cord-298458-p7rvupjo	267	21	,	,	,
cord-298458-p7rvupjo	267	22	and	and	CC
cord-298458-p7rvupjo	267	23	RSV	RSV	NNP
cord-298458-p7rvupjo	267	24	induced	induce	VBD
cord-298458-p7rvupjo	267	25	significantly	significantly	RB
cord-298458-p7rvupjo	267	26	reduced	reduce	VBD
cord-298458-p7rvupjo	267	27	disease	disease	NN
cord-298458-p7rvupjo	267	28	in	in	IN
cord-298458-p7rvupjo	267	29	these	these	DT
cord-298458-p7rvupjo	267	30	mice	mouse	NNS
cord-298458-p7rvupjo	267	31	(	(	-LRB-
cord-298458-p7rvupjo	267	32	30	30	CD
cord-298458-p7rvupjo	267	33	,	,	,
cord-298458-p7rvupjo	267	34	109	109	CD
cord-298458-p7rvupjo	267	35	)	)	-RRB-
cord-298458-p7rvupjo	267	36	.	.	.
cord-298458-p7rvupjo	268	1	Thus	thus	RB
cord-298458-p7rvupjo	268	2	,	,	,
cord-298458-p7rvupjo	268	3	identifying	identify	VBG
cord-298458-p7rvupjo	268	4	the	the	DT
cord-298458-p7rvupjo	268	5	optimal	optimal	JJ
cord-298458-p7rvupjo	268	6	magnitude	magnitude	NN
cord-298458-p7rvupjo	268	7	of	of	IN
cord-298458-p7rvupjo	268	8	RSV	rsv	NN
cord-298458-p7rvupjo	268	9	-	-	HYPH
cord-298458-p7rvupjo	268	10	specific	specific	JJ
cord-298458-p7rvupjo	268	11	CD8	CD8	NNP
cord-298458-p7rvupjo	268	12	T	T	NNP
cord-298458-p7rvupjo	268	13	cells	cell	NNS
cord-298458-p7rvupjo	268	14	for	for	IN
cord-298458-p7rvupjo	268	15	protection	protection	NN
cord-298458-p7rvupjo	268	16	in	in	IN
cord-298458-p7rvupjo	268	17	the	the	DT
cord-298458-p7rvupjo	268	18	absence	absence	NN
cord-298458-p7rvupjo	268	19	of	of	IN
cord-298458-p7rvupjo	268	20	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	268	21	is	be	VBZ
cord-298458-p7rvupjo	268	22	crucial	crucial	JJ
cord-298458-p7rvupjo	268	23	.	.	.
cord-298458-p7rvupjo	269	1	It	-PRON-	PRP
cord-298458-p7rvupjo	269	2	is	be	VBZ
cord-298458-p7rvupjo	269	3	also	also	RB
cord-298458-p7rvupjo	269	4	clear	clear	JJ
cord-298458-p7rvupjo	269	5	from	from	IN
cord-298458-p7rvupjo	269	6	recent	recent	JJ
cord-298458-p7rvupjo	269	7	studies	study	NNS
cord-298458-p7rvupjo	269	8	in	in	IN
cord-298458-p7rvupjo	269	9	mouse	mouse	NN
cord-298458-p7rvupjo	269	10	models	model	NNS
cord-298458-p7rvupjo	269	11	that	that	IN
cord-298458-p7rvupjo	269	12	localization	localization	NN
cord-298458-p7rvupjo	269	13	of	of	IN
cord-298458-p7rvupjo	269	14	RSV	RSV	NNP
cord-298458-p7rvupjo	269	15	-	-	HYPH
cord-298458-p7rvupjo	269	16	specific	specific	JJ
cord-298458-p7rvupjo	269	17	CD8	CD8	NNP
cord-298458-p7rvupjo	269	18	T	T	NNP
cord-298458-p7rvupjo	269	19	cells	cell	NNS
cord-298458-p7rvupjo	269	20	is	be	VBZ
cord-298458-p7rvupjo	269	21	a	a	DT
cord-298458-p7rvupjo	269	22	significant	significant	JJ
cord-298458-p7rvupjo	269	23	factor	factor	NN
cord-298458-p7rvupjo	269	24	for	for	IN
cord-298458-p7rvupjo	269	25	both	both	CC
cord-298458-p7rvupjo	269	26	their	-PRON-	PRP$
cord-298458-p7rvupjo	269	27	efficacy	efficacy	NN
cord-298458-p7rvupjo	269	28	of	of	IN
cord-298458-p7rvupjo	269	29	mediating	mediate	VBG
cord-298458-p7rvupjo	269	30	viral	viral	JJ
cord-298458-p7rvupjo	269	31	clearance	clearance	NN
cord-298458-p7rvupjo	269	32	and	and	CC
cord-298458-p7rvupjo	269	33	their	-PRON-	PRP$
cord-298458-p7rvupjo	269	34	ability	ability	NN
cord-298458-p7rvupjo	269	35	to	to	TO
cord-298458-p7rvupjo	269	36	induce	induce	VB
cord-298458-p7rvupjo	269	37	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	269	38	following	follow	VBG
cord-298458-p7rvupjo	269	39	infection	infection	NN
cord-298458-p7rvupjo	269	40	.	.	.
cord-298458-p7rvupjo	270	1	Intranasal	intranasal	NN
cord-298458-p7rvupjo	270	2	immunization	immunization	NN
cord-298458-p7rvupjo	270	3	with	with	IN
cord-298458-p7rvupjo	270	4	MCMV	MCMV	NNP
cord-298458-p7rvupjo	270	5	-	-	HYPH
cord-298458-p7rvupjo	270	6	M	M	NNP
cord-298458-p7rvupjo	270	7	generated	generate	VBD
cord-298458-p7rvupjo	270	8	TRM	TRM	NNP
cord-298458-p7rvupjo	270	9	within	within	IN
cord-298458-p7rvupjo	270	10	the	the	DT
cord-298458-p7rvupjo	270	11	lung	lung	NN
cord-298458-p7rvupjo	270	12	tissue	tissue	NN
cord-298458-p7rvupjo	270	13	that	that	WDT
cord-298458-p7rvupjo	270	14	accelerated	accelerate	VBD
cord-298458-p7rvupjo	270	15	viral	viral	JJ
cord-298458-p7rvupjo	270	16	clearance	clearance	NN
cord-298458-p7rvupjo	270	17	.	.	.
cord-298458-p7rvupjo	271	1	In	in	IN
cord-298458-p7rvupjo	271	2	contrast	contrast	NN
cord-298458-p7rvupjo	271	3	,	,	,
cord-298458-p7rvupjo	271	4	mice	mouse	NNS
cord-298458-p7rvupjo	271	5	administered	administer	VBD
cord-298458-p7rvupjo	271	6	MCMV	MCMV	NNP
cord-298458-p7rvupjo	271	7	-	-	HYPH
cord-298458-p7rvupjo	271	8	M	M	NNP
cord-298458-p7rvupjo	271	9	systemically	systemically	RB
cord-298458-p7rvupjo	271	10	did	do	VBD
cord-298458-p7rvupjo	271	11	not	not	RB
cord-298458-p7rvupjo	271	12	generate	generate	VB
cord-298458-p7rvupjo	271	13	TRM	TRM	NNP
cord-298458-p7rvupjo	271	14	and	and	CC
cord-298458-p7rvupjo	271	15	exhibited	exhibit	VBD
cord-298458-p7rvupjo	271	16	delayed	delay	VBN
cord-298458-p7rvupjo	271	17	viral	viral	JJ
cord-298458-p7rvupjo	271	18	clearance	clearance	NN
cord-298458-p7rvupjo	271	19	(	(	-LRB-
cord-298458-p7rvupjo	271	20	78	78	CD
cord-298458-p7rvupjo	271	21	)	)	-RRB-
cord-298458-p7rvupjo	271	22	.	.	.
cord-298458-p7rvupjo	272	1	Similar	similar	JJ
cord-298458-p7rvupjo	272	2	results	result	NNS
cord-298458-p7rvupjo	272	3	were	be	VBD
cord-298458-p7rvupjo	272	4	observed	observe	VBN
cord-298458-p7rvupjo	272	5	with	with	IN
cord-298458-p7rvupjo	272	6	local	local	JJ
cord-298458-p7rvupjo	272	7	immunization	immunization	NN
cord-298458-p7rvupjo	272	8	with	with	IN
cord-298458-p7rvupjo	272	9	DC	DC	NNP
cord-298458-p7rvupjo	272	10	-	-	HYPH
cord-298458-p7rvupjo	272	11	IAV	IAV	NNP
cord-298458-p7rvupjo	272	12	-	-	HYPH
cord-298458-p7rvupjo	272	13	M282	M282	NNP
cord-298458-p7rvupjo	272	14	(	(	-LRB-
cord-298458-p7rvupjo	272	15	30	30	CD
cord-298458-p7rvupjo	272	16	)	)	-RRB-
cord-298458-p7rvupjo	272	17	.	.	.
cord-298458-p7rvupjo	273	1	M282-specific	M282-specific	NNP
cord-298458-p7rvupjo	273	2	lung	lung	NN
cord-298458-p7rvupjo	273	3	TRM	TRM	NNP
cord-298458-p7rvupjo	273	4	generated	generate	VBN
cord-298458-p7rvupjo	273	5	by	by	IN
cord-298458-p7rvupjo	273	6	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	273	7	immunization	immunization	NN
cord-298458-p7rvupjo	273	8	did	do	VBD
cord-298458-p7rvupjo	273	9	not	not	RB
cord-298458-p7rvupjo	273	10	induce	induce	VB
cord-298458-p7rvupjo	273	11	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	273	12	following	follow	VBG
cord-298458-p7rvupjo	273	13	RSV	RSV	NNP
cord-298458-p7rvupjo	273	14	infection	infection	NN
cord-298458-p7rvupjo	273	15	,	,	,
cord-298458-p7rvupjo	273	16	in	in	IN
cord-298458-p7rvupjo	273	17	contrast	contrast	NN
cord-298458-p7rvupjo	273	18	to	to	IN
cord-298458-p7rvupjo	273	19	systemic	systemic	JJ
cord-298458-p7rvupjo	273	20	DC	DC	NNP
cord-298458-p7rvupjo	273	21	-	-	HYPH
cord-298458-p7rvupjo	273	22	LM	LM	NNP
cord-298458-p7rvupjo	273	23	immunization	immunization	NN
cord-298458-p7rvupjo	273	24	,	,	,
cord-298458-p7rvupjo	273	25	which	which	WDT
cord-298458-p7rvupjo	273	26	resulted	result	VBD
cord-298458-p7rvupjo	273	27	in	in	IN
cord-298458-p7rvupjo	273	28	severe	severe	JJ
cord-298458-p7rvupjo	273	29	pathology	pathology	NN
cord-298458-p7rvupjo	273	30	in	in	IN
cord-298458-p7rvupjo	273	31	the	the	DT
cord-298458-p7rvupjo	273	32	absence	absence	NN
cord-298458-p7rvupjo	273	33	of	of	IN
cord-298458-p7rvupjo	273	34	TRM	TRM	NNP
cord-298458-p7rvupjo	273	35	cells	cell	NNS
cord-298458-p7rvupjo	273	36	.	.	.
cord-298458-p7rvupjo	274	1	Thus	thus	RB
cord-298458-p7rvupjo	274	2	,	,	,
cord-298458-p7rvupjo	274	3	vaccination	vaccination	NN
cord-298458-p7rvupjo	274	4	strategies	strategy	NNS
cord-298458-p7rvupjo	274	5	against	against	IN
cord-298458-p7rvupjo	274	6	RSV	RSV	NNP
cord-298458-p7rvupjo	274	7	will	will	MD
cord-298458-p7rvupjo	274	8	likely	likely	RB
cord-298458-p7rvupjo	274	9	be	be	VB
cord-298458-p7rvupjo	274	10	the	the	DT
cord-298458-p7rvupjo	274	11	most	most	RBS
cord-298458-p7rvupjo	274	12	effective	effective	JJ
cord-298458-p7rvupjo	274	13	when	when	WRB
cord-298458-p7rvupjo	274	14	administered	administer	VBN
cord-298458-p7rvupjo	274	15	through	through	IN
cord-298458-p7rvupjo	274	16	a	a	DT
cord-298458-p7rvupjo	274	17	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	274	18	route	route	NN
cord-298458-p7rvupjo	274	19	to	to	TO
cord-298458-p7rvupjo	274	20	generate	generate	VB
cord-298458-p7rvupjo	274	21	TRM	TRM	NNP
cord-298458-p7rvupjo	274	22	that	that	WDT
cord-298458-p7rvupjo	274	23	will	will	MD
cord-298458-p7rvupjo	274	24	provide	provide	VB
cord-298458-p7rvupjo	274	25	protection	protection	NN
cord-298458-p7rvupjo	274	26	within	within	IN
cord-298458-p7rvupjo	274	27	the	the	DT
cord-298458-p7rvupjo	274	28	lung	lung	NN
cord-298458-p7rvupjo	274	29	following	follow	VBG
cord-298458-p7rvupjo	274	30	reinfection	reinfection	NN
cord-298458-p7rvupjo	274	31	without	without	IN
cord-298458-p7rvupjo	274	32	inducing	induce	VBG
cord-298458-p7rvupjo	274	33	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	274	34	.	.	.
cord-298458-p7rvupjo	275	1	Lastly	lastly	RB
cord-298458-p7rvupjo	275	2	,	,	,
cord-298458-p7rvupjo	275	3	identifying	identify	VBG
cord-298458-p7rvupjo	275	4	ways	way	NNS
cord-298458-p7rvupjo	275	5	to	to	TO
cord-298458-p7rvupjo	275	6	regulate	regulate	VB
cord-298458-p7rvupjo	275	7	vaccine	vaccine	NN
cord-298458-p7rvupjo	275	8	-	-	HYPH
cord-298458-p7rvupjo	275	9	generated	generate	VBN
cord-298458-p7rvupjo	275	10	CD8	CD8	NNP
cord-298458-p7rvupjo	275	11	T	T	NNP
cord-298458-p7rvupjo	275	12	cell	cell	NN
cord-298458-p7rvupjo	275	13	responses	response	NNS
cord-298458-p7rvupjo	275	14	will	will	MD
cord-298458-p7rvupjo	275	15	likely	likely	RB
cord-298458-p7rvupjo	275	16	reduce	reduce	VB
cord-298458-p7rvupjo	275	17	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	275	18	following	follow	VBG
cord-298458-p7rvupjo	275	19	subsequent	subsequent	JJ
cord-298458-p7rvupjo	275	20	infection	infection	NN
cord-298458-p7rvupjo	275	21	.	.	.
cord-298458-p7rvupjo	276	1	IFN	IFN	NNP
cord-298458-p7rvupjo	276	2	-	-	HYPH
cord-298458-p7rvupjo	276	3	γ	γ	NNP
cord-298458-p7rvupjo	276	4	produced	produce	VBN
cord-298458-p7rvupjo	276	5	by	by	IN
cord-298458-p7rvupjo	276	6	CD8	CD8	NNP
cord-298458-p7rvupjo	276	7	T	T	NNP
cord-298458-p7rvupjo	276	8	cells	cell	NNS
cord-298458-p7rvupjo	276	9	was	be	VBD
cord-298458-p7rvupjo	276	10	the	the	DT
cord-298458-p7rvupjo	276	11	primary	primary	JJ
cord-298458-p7rvupjo	276	12	mediator	mediator	NN
cord-298458-p7rvupjo	276	13	of	of	IN
cord-298458-p7rvupjo	276	14	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	276	15	following	follow	VBG
cord-298458-p7rvupjo	276	16	RSV	RSV	NNP
cord-298458-p7rvupjo	276	17	infection	infection	NN
cord-298458-p7rvupjo	276	18	of	of	IN
cord-298458-p7rvupjo	276	19	DC	DC	NNP
cord-298458-p7rvupjo	276	20	-	-	HYPH
cord-298458-p7rvupjo	276	21	LM	LM	NNP
cord-298458-p7rvupjo	276	22	vaccinated	vaccinate	VBD
cord-298458-p7rvupjo	276	23	mice	mouse	NNS
cord-298458-p7rvupjo	276	24	(	(	-LRB-
cord-298458-p7rvupjo	276	25	30	30	CD
cord-298458-p7rvupjo	276	26	)	)	-RRB-
cord-298458-p7rvupjo	276	27	.	.	.
cord-298458-p7rvupjo	277	1	However	however	RB
cord-298458-p7rvupjo	277	2	,	,	,
cord-298458-p7rvupjo	277	3	neutralization	neutralization	NN
cord-298458-p7rvupjo	277	4	of	of	IN
cord-298458-p7rvupjo	277	5	IFN	IFN	NNP
cord-298458-p7rvupjo	277	6	-	-	HYPH
cord-298458-p7rvupjo	277	7	γ	γ	NNP
cord-298458-p7rvupjo	277	8	had	have	VBD
cord-298458-p7rvupjo	277	9	no	no	DT
cord-298458-p7rvupjo	277	10	effect	effect	NN
cord-298458-p7rvupjo	277	11	on	on	IN
cord-298458-p7rvupjo	277	12	lung	lung	NN
cord-298458-p7rvupjo	277	13	viral	viral	JJ
cord-298458-p7rvupjo	277	14	titers	titer	NNS
cord-298458-p7rvupjo	277	15	,	,	,
cord-298458-p7rvupjo	277	16	suggesting	suggest	VBG
cord-298458-p7rvupjo	277	17	that	that	IN
cord-298458-p7rvupjo	277	18	CD8	CD8	NNP
cord-298458-p7rvupjo	277	19	T	T	NNP
cord-298458-p7rvupjo	277	20	cells	cell	NNS
cord-298458-p7rvupjo	277	21	utilize	utilize	VBP
cord-298458-p7rvupjo	277	22	other	other	JJ
cord-298458-p7rvupjo	277	23	antiviral	antiviral	JJ
cord-298458-p7rvupjo	277	24	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	277	25	to	to	TO
cord-298458-p7rvupjo	277	26	mediate	mediate	VB
cord-298458-p7rvupjo	277	27	viral	viral	JJ
cord-298458-p7rvupjo	277	28	clearance	clearance	NN
cord-298458-p7rvupjo	277	29	in	in	IN
cord-298458-p7rvupjo	277	30	this	this	DT
cord-298458-p7rvupjo	277	31	system	system	NN
cord-298458-p7rvupjo	277	32	.	.	.
cord-298458-p7rvupjo	278	1	Since	since	IN
cord-298458-p7rvupjo	278	2	CD8	CD8	NNP
cord-298458-p7rvupjo	278	3	T	T	NNP
cord-298458-p7rvupjo	278	4	cells	cell	NNS
cord-298458-p7rvupjo	278	5	are	be	VBP
cord-298458-p7rvupjo	278	6	able	able	JJ
cord-298458-p7rvupjo	278	7	to	to	TO
cord-298458-p7rvupjo	278	8	reduce	reduce	VB
cord-298458-p7rvupjo	278	9	viral	viral	JJ
cord-298458-p7rvupjo	278	10	titers	titer	NNS
cord-298458-p7rvupjo	278	11	in	in	IN
cord-298458-p7rvupjo	278	12	the	the	DT
cord-298458-p7rvupjo	278	13	absence	absence	NN
cord-298458-p7rvupjo	278	14	of	of	IN
cord-298458-p7rvupjo	278	15	IFN	IFN	NNP
cord-298458-p7rvupjo	278	16	-	-	HYPH
cord-298458-p7rvupjo	278	17	γ	γ	NNP
cord-298458-p7rvupjo	278	18	,	,	,
cord-298458-p7rvupjo	278	19	reducing	reduce	VBG
cord-298458-p7rvupjo	278	20	the	the	DT
cord-298458-p7rvupjo	278	21	amount	amount	NN
cord-298458-p7rvupjo	278	22	of	of	IN
cord-298458-p7rvupjo	278	23	IFN	IFN	NNP
cord-298458-p7rvupjo	278	24	-	-	HYPH
cord-298458-p7rvupjo	278	25	γ	γ	NNP
cord-298458-p7rvupjo	278	26	produced	produce	VBN
cord-298458-p7rvupjo	278	27	by	by	IN
cord-298458-p7rvupjo	278	28	CD8	CD8	NNP
cord-298458-p7rvupjo	278	29	T	T	NNP
cord-298458-p7rvupjo	278	30	cells	cell	NNS
cord-298458-p7rvupjo	278	31	would	would	MD
cord-298458-p7rvupjo	278	32	likely	likely	RB
cord-298458-p7rvupjo	278	33	result	result	VB
cord-298458-p7rvupjo	278	34	in	in	IN
cord-298458-p7rvupjo	278	35	ameliorated	ameliorated	JJ
cord-298458-p7rvupjo	278	36	disease	disease	NN
cord-298458-p7rvupjo	278	37	following	follow	VBG
cord-298458-p7rvupjo	278	38	RSV	RSV	NNP
cord-298458-p7rvupjo	278	39	infection	infection	NN
cord-298458-p7rvupjo	278	40	.	.	.
cord-298458-p7rvupjo	279	1	If	if	IN
cord-298458-p7rvupjo	279	2	vaccination	vaccination	NN
cord-298458-p7rvupjo	279	3	strategies	strategy	NNS
cord-298458-p7rvupjo	279	4	can	can	MD
cord-298458-p7rvupjo	279	5	identify	identify	VB
cord-298458-p7rvupjo	279	6	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	279	7	by	by	IN
cord-298458-p7rvupjo	279	8	which	which	WDT
cord-298458-p7rvupjo	279	9	CD8	CD8	NNP
cord-298458-p7rvupjo	279	10	T	T	NNP
cord-298458-p7rvupjo	279	11	cell	cell	NN
cord-298458-p7rvupjo	279	12	cytokine	cytokine	NN
cord-298458-p7rvupjo	279	13	production	production	NN
cord-298458-p7rvupjo	279	14	,	,	,
cord-298458-p7rvupjo	279	15	particularly	particularly	RB
cord-298458-p7rvupjo	279	16	IFN	IFN	NNP
cord-298458-p7rvupjo	279	17	-	-	HYPH
cord-298458-p7rvupjo	279	18	γ	γ	NNP
cord-298458-p7rvupjo	279	19	,	,	,
cord-298458-p7rvupjo	279	20	can	can	MD
cord-298458-p7rvupjo	279	21	be	be	VB
cord-298458-p7rvupjo	279	22	attenuated	attenuate	VBN
cord-298458-p7rvupjo	279	23	without	without	IN
cord-298458-p7rvupjo	279	24	altering	alter	VBG
cord-298458-p7rvupjo	279	25	their	-PRON-	PRP$
cord-298458-p7rvupjo	279	26	ability	ability	NN
cord-298458-p7rvupjo	279	27	to	to	TO
cord-298458-p7rvupjo	279	28	eliminate	eliminate	VB
cord-298458-p7rvupjo	279	29	virusinfected	virusinfected	JJ
cord-298458-p7rvupjo	279	30	cells	cell	NNS
cord-298458-p7rvupjo	279	31	,	,	,
cord-298458-p7rvupjo	279	32	the	the	DT
cord-298458-p7rvupjo	279	33	pathology	pathology	NN
cord-298458-p7rvupjo	279	34	induced	induce	VBN
cord-298458-p7rvupjo	279	35	by	by	IN
cord-298458-p7rvupjo	279	36	CD8	CD8	NNP
cord-298458-p7rvupjo	279	37	T	T	NNP
cord-298458-p7rvupjo	279	38	cells	cell	NNS
cord-298458-p7rvupjo	279	39	would	would	MD
cord-298458-p7rvupjo	279	40	likely	likely	RB
cord-298458-p7rvupjo	279	41	also	also	RB
cord-298458-p7rvupjo	279	42	be	be	VB
cord-298458-p7rvupjo	279	43	decreased	decrease	VBN
cord-298458-p7rvupjo	279	44	.	.	.
cord-298458-p7rvupjo	280	1	The	the	DT
cord-298458-p7rvupjo	280	2	development	development	NN
cord-298458-p7rvupjo	280	3	of	of	IN
cord-298458-p7rvupjo	280	4	a	a	DT
cord-298458-p7rvupjo	280	5	CD8	CD8	NNP
cord-298458-p7rvupjo	280	6	T	T	NNP
cord-298458-p7rvupjo	280	7	cell	cell	NN
cord-298458-p7rvupjo	280	8	-	-	HYPH
cord-298458-p7rvupjo	280	9	mediated	mediate	VBN
cord-298458-p7rvupjo	280	10	vaccine	vaccine	NN
cord-298458-p7rvupjo	280	11	should	should	MD
cord-298458-p7rvupjo	280	12	be	be	VB
cord-298458-p7rvupjo	280	13	pursued	pursue	VBN
cord-298458-p7rvupjo	280	14	given	give	VBN
cord-298458-p7rvupjo	280	15	the	the	DT
cord-298458-p7rvupjo	280	16	limitations	limitation	NNS
cord-298458-p7rvupjo	280	17	of	of	IN
cord-298458-p7rvupjo	280	18	antibody	antibody	NN
cord-298458-p7rvupjo	280	19	responses	response	NNS
cord-298458-p7rvupjo	280	20	to	to	IN
cord-298458-p7rvupjo	280	21	respiratory	respiratory	JJ
cord-298458-p7rvupjo	280	22	viruses	virus	NNS
cord-298458-p7rvupjo	280	23	.	.	.
cord-298458-p7rvupjo	281	1	It	-PRON-	PRP
cord-298458-p7rvupjo	281	2	is	be	VBZ
cord-298458-p7rvupjo	281	3	possible	possible	JJ
cord-298458-p7rvupjo	281	4	that	that	IN
cord-298458-p7rvupjo	281	5	the	the	DT
cord-298458-p7rvupjo	281	6	ideal	ideal	JJ
cord-298458-p7rvupjo	281	7	vaccine	vaccine	NN
cord-298458-p7rvupjo	281	8	for	for	IN
cord-298458-p7rvupjo	281	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	281	10	virus	virus	NN
cord-298458-p7rvupjo	281	11	infections	infection	NNS
cord-298458-p7rvupjo	281	12	will	will	MD
cord-298458-p7rvupjo	281	13	include	include	VB
cord-298458-p7rvupjo	281	14	the	the	DT
cord-298458-p7rvupjo	281	15	induction	induction	NN
cord-298458-p7rvupjo	281	16	of	of	IN
cord-298458-p7rvupjo	281	17	both	both	DT
cord-298458-p7rvupjo	281	18	virus	virus	NN
cord-298458-p7rvupjo	281	19	-	-	HYPH
cord-298458-p7rvupjo	281	20	specific	specific	JJ
cord-298458-p7rvupjo	281	21	CD8	CD8	NNP
cord-298458-p7rvupjo	281	22	T	T	NNP
cord-298458-p7rvupjo	281	23	cells	cell	NNS
cord-298458-p7rvupjo	281	24	and	and	CC
cord-298458-p7rvupjo	281	25	neutralizing	neutralize	VBG
cord-298458-p7rvupjo	281	26	antibodies	antibody	NNS
cord-298458-p7rvupjo	281	27	.	.	.
cord-298458-p7rvupjo	282	1	A	a	DT
cord-298458-p7rvupjo	282	2	vaccination	vaccination	NN
cord-298458-p7rvupjo	282	3	approach	approach	NN
cord-298458-p7rvupjo	282	4	combining	combine	VBG
cord-298458-p7rvupjo	282	5	both	both	DT
cord-298458-p7rvupjo	282	6	arms	arm	NNS
cord-298458-p7rvupjo	282	7	of	of	IN
cord-298458-p7rvupjo	282	8	the	the	DT
cord-298458-p7rvupjo	282	9	adaptive	adaptive	JJ
cord-298458-p7rvupjo	282	10	immune	immune	JJ
cord-298458-p7rvupjo	282	11	response	response	NN
cord-298458-p7rvupjo	282	12	may	may	MD
cord-298458-p7rvupjo	282	13	allow	allow	VB
cord-298458-p7rvupjo	282	14	for	for	IN
cord-298458-p7rvupjo	282	15	optimal	optimal	JJ
cord-298458-p7rvupjo	282	16	viral	viral	JJ
cord-298458-p7rvupjo	282	17	control	control	NN
cord-298458-p7rvupjo	282	18	in	in	IN
cord-298458-p7rvupjo	282	19	the	the	DT
cord-298458-p7rvupjo	282	20	absence	absence	NN
cord-298458-p7rvupjo	282	21	of	of	IN
cord-298458-p7rvupjo	282	22	disease	disease	NN
cord-298458-p7rvupjo	282	23	symptoms	symptom	NNS
cord-298458-p7rvupjo	282	24	.	.	.
cord-298458-p7rvupjo	283	1	However	however	RB
cord-298458-p7rvupjo	283	2	,	,	,
cord-298458-p7rvupjo	283	3	before	before	IN
cord-298458-p7rvupjo	283	4	CD8	CD8	NNP
cord-298458-p7rvupjo	283	5	T	T	NNP
cord-298458-p7rvupjo	283	6	cells	cell	NNS
cord-298458-p7rvupjo	283	7	can	can	MD
cord-298458-p7rvupjo	283	8	be	be	VB
cord-298458-p7rvupjo	283	9	developed	develop	VBN
cord-298458-p7rvupjo	283	10	further	further	RB
cord-298458-p7rvupjo	283	11	as	as	IN
cord-298458-p7rvupjo	283	12	a	a	DT
cord-298458-p7rvupjo	283	13	mediator	mediator	NN
cord-298458-p7rvupjo	283	14	of	of	IN
cord-298458-p7rvupjo	283	15	protective	protective	JJ
cord-298458-p7rvupjo	283	16	immunity	immunity	NN
cord-298458-p7rvupjo	283	17	,	,	,
cord-298458-p7rvupjo	283	18	the	the	DT
cord-298458-p7rvupjo	283	19	balance	balance	NN
cord-298458-p7rvupjo	283	20	between	between	IN
cord-298458-p7rvupjo	283	21	protection	protection	NN
cord-298458-p7rvupjo	283	22	and	and	CC
cord-298458-p7rvupjo	283	23	pathology	pathology	NN
cord-298458-p7rvupjo	283	24	must	must	MD
cord-298458-p7rvupjo	283	25	be	be	VB
cord-298458-p7rvupjo	283	26	achieved	achieve	VBN
cord-298458-p7rvupjo	283	27	.	.	.
cord-298458-p7rvupjo	284	1	Future	future	JJ
cord-298458-p7rvupjo	284	2	studies	study	NNS
cord-298458-p7rvupjo	284	3	evaluating	evaluate	VBG
cord-298458-p7rvupjo	284	4	aspects	aspect	NNS
cord-298458-p7rvupjo	284	5	of	of	IN
cord-298458-p7rvupjo	284	6	memory	memory	NN
cord-298458-p7rvupjo	284	7	CD8	CD8	NNP
cord-298458-p7rvupjo	284	8	T	T	NNP
cord-298458-p7rvupjo	284	9	cell	cell	NN
cord-298458-p7rvupjo	284	10	magnitude	magnitude	NN
cord-298458-p7rvupjo	284	11	,	,	,
cord-298458-p7rvupjo	284	12	localization	localization	NN
cord-298458-p7rvupjo	284	13	,	,	,
cord-298458-p7rvupjo	284	14	and	and	CC
cord-298458-p7rvupjo	284	15	regulation	regulation	NN
cord-298458-p7rvupjo	284	16	will	will	MD
cord-298458-p7rvupjo	284	17	greatly	greatly	RB
cord-298458-p7rvupjo	284	18	assist	assist	VB
cord-298458-p7rvupjo	284	19	in	in	IN
cord-298458-p7rvupjo	284	20	reaching	reach	VBG
cord-298458-p7rvupjo	284	21	this	this	DT
cord-298458-p7rvupjo	284	22	balance	balance	NN
cord-298458-p7rvupjo	284	23	.	.	.
cord-298458-p7rvupjo	285	1	Both	both	DT
cord-298458-p7rvupjo	285	2	authors	author	NNS
cord-298458-p7rvupjo	285	3	wrote	write	VBD
cord-298458-p7rvupjo	285	4	and	and	CC
cord-298458-p7rvupjo	285	5	edited	edit	VBD
cord-298458-p7rvupjo	285	6	the	the	DT
cord-298458-p7rvupjo	285	7	manuscript	manuscript	NN
cord-298458-p7rvupjo	285	8	.	.	.
cord-298458-p7rvupjo	285	9	 	 	_SP
cord-298458-p7rvupjo	286	1	Incubation	incubation	NN
cord-298458-p7rvupjo	286	2	periods	period	NNS
cord-298458-p7rvupjo	286	3	of	of	IN
cord-298458-p7rvupjo	286	4	acute	acute	JJ
cord-298458-p7rvupjo	286	5	respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	6	viral	viral	JJ
cord-298458-p7rvupjo	286	7	infections	infection	NNS
cord-298458-p7rvupjo	286	8	:	:	:
cord-298458-p7rvupjo	286	9	a	a	DT
cord-298458-p7rvupjo	286	10	systematic	systematic	JJ
cord-298458-p7rvupjo	286	11	review	review	NN
cord-298458-p7rvupjo	286	12	Global	global	JJ
cord-298458-p7rvupjo	286	13	burden	burden	NN
cord-298458-p7rvupjo	286	14	of	of	IN
cord-298458-p7rvupjo	286	15	acute	acute	JJ
cord-298458-p7rvupjo	286	16	lower	low	JJR
cord-298458-p7rvupjo	286	17	respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	18	infections	infection	NNS
cord-298458-p7rvupjo	286	19	due	due	JJ
cord-298458-p7rvupjo	286	20	to	to	IN
cord-298458-p7rvupjo	286	21	respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	22	syncytial	syncytial	JJ
cord-298458-p7rvupjo	286	23	virus	virus	NN
cord-298458-p7rvupjo	286	24	in	in	IN
cord-298458-p7rvupjo	286	25	young	young	JJ
cord-298458-p7rvupjo	286	26	children	child	NNS
cord-298458-p7rvupjo	286	27	:	:	:
cord-298458-p7rvupjo	286	28	a	a	DT
cord-298458-p7rvupjo	286	29	systematic	systematic	JJ
cord-298458-p7rvupjo	286	30	review	review	NN
cord-298458-p7rvupjo	286	31	and	and	CC
cord-298458-p7rvupjo	286	32	meta	meta	NNP
cord-298458-p7rvupjo	286	33	-	-	HYPH
cord-298458-p7rvupjo	286	34	analysis	analysis	NN
cord-298458-p7rvupjo	286	35	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	36	syncytial	syncytial	JJ
cord-298458-p7rvupjo	286	37	viral	viral	JJ
cord-298458-p7rvupjo	286	38	infection	infection	NN
cord-298458-p7rvupjo	286	39	in	in	IN
cord-298458-p7rvupjo	286	40	children	child	NNS
cord-298458-p7rvupjo	286	41	with	with	IN
cord-298458-p7rvupjo	286	42	compromised	compromise	VBN
cord-298458-p7rvupjo	286	43	immune	immune	JJ
cord-298458-p7rvupjo	286	44	function	function	NN
cord-298458-p7rvupjo	286	45	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	46	syncytial	syncytial	JJ
cord-298458-p7rvupjo	286	47	virus	virus	NN
cord-298458-p7rvupjo	286	48	and	and	CC
cord-298458-p7rvupjo	286	49	influenza	influenza	NN
cord-298458-p7rvupjo	286	50	A	a	DT
cord-298458-p7rvupjo	286	51	infections	infection	NNS
cord-298458-p7rvupjo	286	52	in	in	IN
cord-298458-p7rvupjo	286	53	the	the	DT
cord-298458-p7rvupjo	286	54	hospitalized	hospitalize	VBN
cord-298458-p7rvupjo	286	55	elderly	elderly	JJ
cord-298458-p7rvupjo	286	56	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	57	syncytial	syncytial	JJ
cord-298458-p7rvupjo	286	58	virus	virus	NN
cord-298458-p7rvupjo	286	59	infection	infection	NN
cord-298458-p7rvupjo	286	60	in	in	IN
cord-298458-p7rvupjo	286	61	elderly	elderly	JJ
cord-298458-p7rvupjo	286	62	and	and	CC
cord-298458-p7rvupjo	286	63	high	high	JJ
cord-298458-p7rvupjo	286	64	-	-	HYPH
cord-298458-p7rvupjo	286	65	risk	risk	NN
cord-298458-p7rvupjo	286	66	adults	adult	NNS
cord-298458-p7rvupjo	286	67	Influenza	Influenza	NNP
cord-298458-p7rvupjo	286	68	-	-	:
cord-298458-p7rvupjo	286	69	and	and	CC
cord-298458-p7rvupjo	286	70	respiratory	respiratory	JJ
cord-298458-p7rvupjo	286	71	syncytial	syncytial	JJ
cord-298458-p7rvupjo	286	72	virus	virus	NN
cord-298458-p7rvupjo	286	73	-	-	HYPH
cord-298458-p7rvupjo	286	74	associated	associate	VBN
cord-298458-p7rvupjo	286	75	mortality	mortality	NN
cord-298458-p7rvupjo	286	76	and	and	CC
cord-298458-p7rvupjo	286	77	hospitalisations	hospitalisation	NNS
cord-298458-p7rvupjo	286	78	Epidemiology	epidemiology	NN
cord-298458-p7rvupjo	286	79	and	and	CC
cord-298458-p7rvupjo	286	80	clinical	clinical	JJ
cord-298458-p7rvupjo	286	81	impact	impact	NN
cord-298458-p7rvupjo	286	82	of	of	IN
cord-298458-p7rvupjo	286	83	parainfluenza	parainfluenza	NNP
cord-298458-p7rvupjo	286	84	virus	virus	NN
cord-298458-p7rvupjo	286	85	infections	infection	NNS
cord-298458-p7rvupjo	286	86	in	in	IN
cord-298458-p7rvupjo	286	87	otherwise	otherwise	RB
cord-298458-p7rvupjo	286	88	healthy	healthy	JJ
cord-298458-p7rvupjo	286	89	infants	infant	NNS
cord-298458-p7rvupjo	286	90	and	and	CC
cord-298458-p7rvupjo	286	91	young	young	JJ
cord-298458-p7rvupjo	286	92	children	child	NNS
cord-298458-p7rvupjo	287	1	<	<	NNP
cord-298458-p7rvupjo	287	2	5	5	CD
cord-298458-p7rvupjo	287	3	years	year	NNS
cord-298458-p7rvupjo	287	4	old	old	JJ
cord-298458-p7rvupjo	287	5	Parainfluenza	Parainfluenza	NNP
cord-298458-p7rvupjo	287	6	viruses	virus	NNS
cord-298458-p7rvupjo	287	7	Estimates	estimate	NNS
cord-298458-p7rvupjo	287	8	of	of	IN
cord-298458-p7rvupjo	287	9	US	US	NNP
cord-298458-p7rvupjo	287	10	influenza	influenza	NN
cord-298458-p7rvupjo	287	11	-	-	HYPH
cord-298458-p7rvupjo	287	12	associated	associate	VBN
cord-298458-p7rvupjo	287	13	deaths	death	NNS
cord-298458-p7rvupjo	287	14	made	make	VBD
cord-298458-p7rvupjo	287	15	using	use	VBG
cord-298458-p7rvupjo	287	16	four	four	CD
cord-298458-p7rvupjo	287	17	different	different	JJ
cord-298458-p7rvupjo	287	18	methods	method	NNS
cord-298458-p7rvupjo	287	19	.	.	.
cord-298458-p7rvupjo	288	1	Influenza	Influenza	NNP
cord-298458-p7rvupjo	288	2	Other	other	JJ
cord-298458-p7rvupjo	288	3	Respir	Respir	NNP
cord-298458-p7rvupjo	288	4	Viruses	virus	NNS
cord-298458-p7rvupjo	288	5	Global	global	JJ
cord-298458-p7rvupjo	288	6	burden	burden	NN
cord-298458-p7rvupjo	288	7	of	of	IN
cord-298458-p7rvupjo	288	8	respiratory	respiratory	JJ
cord-298458-p7rvupjo	288	9	infections	infection	NNS
cord-298458-p7rvupjo	288	10	due	due	JJ
cord-298458-p7rvupjo	288	11	to	to	IN
cord-298458-p7rvupjo	288	12	seasonal	seasonal	JJ
cord-298458-p7rvupjo	288	13	influenza	influenza	NN
cord-298458-p7rvupjo	288	14	in	in	IN
cord-298458-p7rvupjo	288	15	young	young	JJ
cord-298458-p7rvupjo	288	16	children	child	NNS
cord-298458-p7rvupjo	288	17	:	:	:
cord-298458-p7rvupjo	288	18	a	a	DT
cord-298458-p7rvupjo	288	19	systematic	systematic	JJ
cord-298458-p7rvupjo	288	20	review	review	NN
cord-298458-p7rvupjo	288	21	and	and	CC
cord-298458-p7rvupjo	288	22	meta	meta	NNP
cord-298458-p7rvupjo	288	23	-	-	HYPH
cord-298458-p7rvupjo	288	24	analysis	analysis	NN
cord-298458-p7rvupjo	289	1	Estimated	estimate	VBN
cord-298458-p7rvupjo	289	2	global	global	JJ
cord-298458-p7rvupjo	289	3	mortality	mortality	NN
cord-298458-p7rvupjo	289	4	associated	associate	VBN
cord-298458-p7rvupjo	289	5	with	with	IN
cord-298458-p7rvupjo	289	6	the	the	DT
cord-298458-p7rvupjo	289	7	first	first	JJ
cord-298458-p7rvupjo	289	8	12	12	CD
cord-298458-p7rvupjo	289	9	months	month	NNS
cord-298458-p7rvupjo	289	10	of	of	IN
cord-298458-p7rvupjo	289	11	2009	2009	CD
cord-298458-p7rvupjo	289	12	pandemic	pandemic	NN
cord-298458-p7rvupjo	289	13	influenza	influenza	NN
cord-298458-p7rvupjo	289	14	A	a	DT
cord-298458-p7rvupjo	289	15	H1N1	H1N1	NNP
cord-298458-p7rvupjo	289	16	virus	virus	NN
cord-298458-p7rvupjo	289	17	circulation	circulation	NN
cord-298458-p7rvupjo	289	18	:	:	:
cord-298458-p7rvupjo	289	19	a	a	DT
cord-298458-p7rvupjo	289	20	modelling	modelling	NN
cord-298458-p7rvupjo	289	21	study	study	NN
cord-298458-p7rvupjo	289	22	Viruses	virus	NNS
cord-298458-p7rvupjo	289	23	and	and	CC
cord-298458-p7rvupjo	289	24	bacteria	bacteria	NNS
cord-298458-p7rvupjo	289	25	in	in	IN
cord-298458-p7rvupjo	289	26	the	the	DT
cord-298458-p7rvupjo	289	27	etiology	etiology	NN
cord-298458-p7rvupjo	289	28	of	of	IN
cord-298458-p7rvupjo	289	29	the	the	DT
cord-298458-p7rvupjo	289	30	common	common	JJ
cord-298458-p7rvupjo	289	31	cold	cold	JJ
cord-298458-p7rvupjo	289	32	Human	Human	NNP
cord-298458-p7rvupjo	289	33	metapneumovirus	metapneumovirus	NN
cord-298458-p7rvupjo	289	34	and	and	CC
cord-298458-p7rvupjo	289	35	lower	low	JJR
cord-298458-p7rvupjo	289	36	respiratory	respiratory	JJ
cord-298458-p7rvupjo	289	37	tract	tract	NN
cord-298458-p7rvupjo	289	38	disease	disease	NN
cord-298458-p7rvupjo	289	39	in	in	IN
cord-298458-p7rvupjo	289	40	otherwise	otherwise	RB
cord-298458-p7rvupjo	289	41	healthy	healthy	JJ
cord-298458-p7rvupjo	289	42	infants	infant	NNS
cord-298458-p7rvupjo	289	43	and	and	CC
cord-298458-p7rvupjo	289	44	children	child	NNS
cord-298458-p7rvupjo	289	45	Clinical	clinical	JJ
cord-298458-p7rvupjo	289	46	disease	disease	NN
cord-298458-p7rvupjo	289	47	in	in	IN
cord-298458-p7rvupjo	289	48	children	child	NNS
cord-298458-p7rvupjo	289	49	associated	associate	VBN
cord-298458-p7rvupjo	289	50	with	with	IN
cord-298458-p7rvupjo	289	51	newly	newly	RB
cord-298458-p7rvupjo	289	52	described	describe	VBN
cord-298458-p7rvupjo	289	53	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	289	54	subtypes	subtype	NNS
cord-298458-p7rvupjo	290	1	A	a	DT
cord-298458-p7rvupjo	290	2	novel	novel	JJ
cord-298458-p7rvupjo	290	3	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	290	4	associated	associate	VBN
cord-298458-p7rvupjo	290	5	with	with	IN
cord-298458-p7rvupjo	290	6	severe	severe	JJ
cord-298458-p7rvupjo	290	7	acute	acute	JJ
cord-298458-p7rvupjo	290	8	respiratory	respiratory	JJ
cord-298458-p7rvupjo	290	9	syndrome	syndrome	NN
cord-298458-p7rvupjo	290	10	Coronavirus	Coronavirus	NNP
cord-298458-p7rvupjo	290	11	as	as	IN
cord-298458-p7rvupjo	290	12	a	a	DT
cord-298458-p7rvupjo	290	13	possible	possible	JJ
cord-298458-p7rvupjo	290	14	cause	cause	NN
cord-298458-p7rvupjo	290	15	of	of	IN
cord-298458-p7rvupjo	290	16	severe	severe	JJ
cord-298458-p7rvupjo	290	17	acute	acute	JJ
cord-298458-p7rvupjo	290	18	respiratory	respiratory	JJ
cord-298458-p7rvupjo	290	19	syndrome	syndrome	NN
cord-298458-p7rvupjo	290	20	Isolation	isolation	NN
cord-298458-p7rvupjo	290	21	of	of	IN
cord-298458-p7rvupjo	290	22	a	a	DT
cord-298458-p7rvupjo	290	23	novel	novel	JJ
cord-298458-p7rvupjo	290	24	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	290	25	from	from	IN
cord-298458-p7rvupjo	290	26	a	a	DT
cord-298458-p7rvupjo	290	27	man	man	NN
cord-298458-p7rvupjo	290	28	with	with	IN
cord-298458-p7rvupjo	290	29	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	290	30	in	in	IN
cord-298458-p7rvupjo	290	31	Saudi	Saudi	NNP
cord-298458-p7rvupjo	290	32	Arabia	Arabia	NNP
cord-298458-p7rvupjo	290	33	Risk	Risk	NNP
cord-298458-p7rvupjo	290	34	of	of	IN
cord-298458-p7rvupjo	290	35	primary	primary	JJ
cord-298458-p7rvupjo	290	36	infection	infection	NN
cord-298458-p7rvupjo	290	37	and	and	CC
cord-298458-p7rvupjo	290	38	reinfection	reinfection	NN
cord-298458-p7rvupjo	290	39	with	with	IN
cord-298458-p7rvupjo	290	40	respiratory	respiratory	JJ
cord-298458-p7rvupjo	290	41	syncytial	syncytial	JJ
cord-298458-p7rvupjo	290	42	virus	virus	NN
cord-298458-p7rvupjo	291	1	The	the	DT
cord-298458-p7rvupjo	291	2	role	role	NN
cord-298458-p7rvupjo	291	3	of	of	IN
cord-298458-p7rvupjo	291	4	human	human	JJ
cord-298458-p7rvupjo	291	5	metapneumovirus	metapneumovirus	NN
cord-298458-p7rvupjo	291	6	in	in	IN
cord-298458-p7rvupjo	291	7	upper	upper	JJ
cord-298458-p7rvupjo	291	8	respiratory	respiratory	JJ
cord-298458-p7rvupjo	291	9	tract	tract	NN
cord-298458-p7rvupjo	291	10	infec	infec	IN
cord-298458-p7rvupjo	291	11	tions	tion	NNS
cord-298458-p7rvupjo	291	12	in	in	IN
cord-298458-p7rvupjo	291	13	children	child	NNS
cord-298458-p7rvupjo	291	14	:	:	:
cord-298458-p7rvupjo	291	15	a	a	DT
cord-298458-p7rvupjo	291	16	20-year	20-year	JJ
cord-298458-p7rvupjo	291	17	experience	experience	NN
cord-298458-p7rvupjo	291	18	Prolonged	prolong	VBN
cord-298458-p7rvupjo	291	19	shedding	shedding	NN
cord-298458-p7rvupjo	291	20	of	of	IN
cord-298458-p7rvupjo	291	21	rhinovirus	rhinovirus	NN
cord-298458-p7rvupjo	291	22	and	and	CC
cord-298458-p7rvupjo	291	23	re	re	NN
cord-298458-p7rvupjo	291	24	-	-	NN
cord-298458-p7rvupjo	291	25	infection	infection	NN
cord-298458-p7rvupjo	291	26	in	in	IN
cord-298458-p7rvupjo	291	27	adults	adult	NNS
cord-298458-p7rvupjo	291	28	with	with	IN
cord-298458-p7rvupjo	291	29	respiratory	respiratory	JJ
cord-298458-p7rvupjo	291	30	tract	tract	NN
cord-298458-p7rvupjo	291	31	illness	illness	NN
cord-298458-p7rvupjo	291	32	Changes	change	NNS
cord-298458-p7rvupjo	291	33	in	in	IN
cord-298458-p7rvupjo	291	34	IgA	IgA	NNP
cord-298458-p7rvupjo	291	35	and	and	CC
cord-298458-p7rvupjo	291	36	IgG	IgG	NNP
cord-298458-p7rvupjo	291	37	concentrations	concentration	NNS
cord-298458-p7rvupjo	291	38	in	in	IN
cord-298458-p7rvupjo	291	39	nasal	nasal	NN
cord-298458-p7rvupjo	291	40	secretions	secretion	NNS
cord-298458-p7rvupjo	291	41	prior	prior	RB
cord-298458-p7rvupjo	291	42	to	to	IN
cord-298458-p7rvupjo	291	43	the	the	DT
cord-298458-p7rvupjo	291	44	appearance	appearance	NN
cord-298458-p7rvupjo	291	45	of	of	IN
cord-298458-p7rvupjo	291	46	antibody	antibody	NN
cord-298458-p7rvupjo	291	47	during	during	IN
cord-298458-p7rvupjo	291	48	viral	viral	JJ
cord-298458-p7rvupjo	291	49	respiratory	respiratory	JJ
cord-298458-p7rvupjo	291	50	infection	infection	NN
cord-298458-p7rvupjo	291	51	in	in	IN
cord-298458-p7rvupjo	292	1	man	man	NN
cord-298458-p7rvupjo	292	2	Impaired	impaired	JJ
cord-298458-p7rvupjo	292	3	antibody	antibody	NN
cord-298458-p7rvupjo	292	4	-	-	HYPH
cord-298458-p7rvupjo	292	5	mediated	mediate	VBN
cord-298458-p7rvupjo	292	6	protection	protection	NN
cord-298458-p7rvupjo	292	7	and	and	CC
cord-298458-p7rvupjo	292	8	defective	defective	JJ
cord-298458-p7rvupjo	292	9	IgA	IgA	NNP
cord-298458-p7rvupjo	292	10	B	b	NN
cord-298458-p7rvupjo	292	11	-	-	HYPH
cord-298458-p7rvupjo	292	12	cell	cell	NN
cord-298458-p7rvupjo	292	13	memory	memory	NN
cord-298458-p7rvupjo	292	14	in	in	IN
cord-298458-p7rvupjo	292	15	experimental	experimental	JJ
cord-298458-p7rvupjo	292	16	infection	infection	NN
cord-298458-p7rvupjo	292	17	of	of	IN
cord-298458-p7rvupjo	292	18	adults	adult	NNS
cord-298458-p7rvupjo	292	19	with	with	IN
cord-298458-p7rvupjo	292	20	respiratory	respiratory	JJ
cord-298458-p7rvupjo	292	21	syncytial	syncytial	JJ
cord-298458-p7rvupjo	292	22	virus	virus	NN
cord-298458-p7rvupjo	292	23	Antibody	Antibody	NNP
cord-298458-p7rvupjo	292	24	and	and	CC
cord-298458-p7rvupjo	292	25	Th1-type	Th1-type	NNP
cord-298458-p7rvupjo	292	26	cell	cell	NN
cord-298458-p7rvupjo	292	27	-	-	HYPH
cord-298458-p7rvupjo	292	28	mediated	mediate	VBN
cord-298458-p7rvupjo	292	29	immune	immune	JJ
cord-298458-p7rvupjo	292	30	responses	response	NNS
cord-298458-p7rvupjo	292	31	in	in	IN
cord-298458-p7rvupjo	292	32	elderly	elderly	JJ
cord-298458-p7rvupjo	292	33	and	and	CC
cord-298458-p7rvupjo	292	34	young	young	JJ
cord-298458-p7rvupjo	292	35	adults	adult	NNS
cord-298458-p7rvupjo	292	36	immunized	immunize	VBN
cord-298458-p7rvupjo	292	37	with	with	IN
cord-298458-p7rvupjo	292	38	the	the	DT
cord-298458-p7rvupjo	292	39	standard	standard	NN
cord-298458-p7rvupjo	292	40	or	or	CC
cord-298458-p7rvupjo	292	41	a	a	DT
cord-298458-p7rvupjo	292	42	high	high	JJ
cord-298458-p7rvupjo	292	43	dose	dose	NN
cord-298458-p7rvupjo	292	44	influenza	influenza	NN
cord-298458-p7rvupjo	292	45	vaccine	vaccine	NN
cord-298458-p7rvupjo	292	46	Influenza	Influenza	NNP
cord-298458-p7rvupjo	292	47	nucleoprotein	nucleoprotein	NNP
cord-298458-p7rvupjo	292	48	-	-	HYPH
cord-298458-p7rvupjo	292	49	specific	specific	JJ
cord-298458-p7rvupjo	292	50	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	292	51	T	t	NN
cord-298458-p7rvupjo	292	52	-	-	HYPH
cord-298458-p7rvupjo	292	53	cell	cell	NN
cord-298458-p7rvupjo	292	54	clones	clone	NNS
cord-298458-p7rvupjo	292	55	are	be	VBP
cord-298458-p7rvupjo	292	56	protective	protective	JJ
cord-298458-p7rvupjo	292	57	in	in	IN
cord-298458-p7rvupjo	292	58	vivo	vivo	NN
cord-298458-p7rvupjo	292	59	Role	role	NN
cord-298458-p7rvupjo	292	60	of	of	IN
cord-298458-p7rvupjo	292	61	T	T	NNP
cord-298458-p7rvupjo	292	62	lymphocyte	lymphocyte	NN
cord-298458-p7rvupjo	292	63	subsets	subset	NNS
cord-298458-p7rvupjo	292	64	in	in	IN
cord-298458-p7rvupjo	292	65	the	the	DT
cord-298458-p7rvupjo	292	66	pathogenesis	pathogenesis	NN
cord-298458-p7rvupjo	292	67	of	of	IN
cord-298458-p7rvupjo	292	68	primary	primary	JJ
cord-298458-p7rvupjo	292	69	infection	infection	NN
cord-298458-p7rvupjo	292	70	and	and	CC
cord-298458-p7rvupjo	292	71	rechallenge	rechallenge	NN
cord-298458-p7rvupjo	292	72	with	with	IN
cord-298458-p7rvupjo	292	73	respiratory	respiratory	JJ
cord-298458-p7rvupjo	292	74	syncytial	syncytial	JJ
cord-298458-p7rvupjo	292	75	virus	virus	NN
cord-298458-p7rvupjo	292	76	in	in	IN
cord-298458-p7rvupjo	292	77	mice	mouse	NNS
cord-298458-p7rvupjo	292	78	Mapping	mapping	NN
cord-298458-p7rvupjo	292	79	and	and	CC
cord-298458-p7rvupjo	292	80	characterization	characterization	NN
cord-298458-p7rvupjo	292	81	of	of	IN
cord-298458-p7rvupjo	292	82	the	the	DT
cord-298458-p7rvupjo	292	83	primary	primary	JJ
cord-298458-p7rvupjo	292	84	and	and	CC
cord-298458-p7rvupjo	292	85	anamnestic	anamnestic	JJ
cord-298458-p7rvupjo	292	86	H-2d	h-2d	RB
cord-298458-p7rvupjo	292	87	-	-	HYPH
cord-298458-p7rvupjo	292	88	restricted	restrict	VBN
cord-298458-p7rvupjo	292	89	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	292	90	T	t	NN
cord-298458-p7rvupjo	292	91	-	-	HYPH
cord-298458-p7rvupjo	292	92	lymphocyte	lymphocyte	NN
cord-298458-p7rvupjo	292	93	response	response	NN
cord-298458-p7rvupjo	292	94	in	in	IN
cord-298458-p7rvupjo	292	95	mice	mouse	NNS
cord-298458-p7rvupjo	292	96	against	against	IN
cord-298458-p7rvupjo	292	97	human	human	NNP
cord-298458-p7rvupjo	292	98	meta	meta	NNP
cord-298458-p7rvupjo	292	99	pneumovirus	pneumovirus	NNP
cord-298458-p7rvupjo	293	1	Lung	Lung	NNP
cord-298458-p7rvupjo	293	2	airway	airway	NN
cord-298458-p7rvupjo	293	3	-	-	HYPH
cord-298458-p7rvupjo	293	4	surveilling	surveille	VBG
cord-298458-p7rvupjo	293	5	CXCR3(hi	CXCR3(hi	NNP
cord-298458-p7rvupjo	293	6	)	)	-RRB-
cord-298458-p7rvupjo	293	7	memory	memory	NN
cord-298458-p7rvupjo	293	8	CD8	CD8	NNP
cord-298458-p7rvupjo	293	9	+	+	CC
cord-298458-p7rvupjo	293	10	T	T	NNP
cord-298458-p7rvupjo	293	11	cells	cell	NNS
cord-298458-p7rvupjo	293	12	are	be	VBP
cord-298458-p7rvupjo	293	13	critical	critical	JJ
cord-298458-p7rvupjo	293	14	for	for	IN
cord-298458-p7rvupjo	293	15	protection	protection	NN
cord-298458-p7rvupjo	293	16	against	against	IN
cord-298458-p7rvupjo	293	17	influenza	influenza	NN
cord-298458-p7rvupjo	293	18	A	a	DT
cord-298458-p7rvupjo	293	19	virus	virus	NN
cord-298458-p7rvupjo	293	20	Virus	virus	NN
cord-298458-p7rvupjo	293	21	-	-	HYPH
cord-298458-p7rvupjo	293	22	specific	specific	JJ
cord-298458-p7rvupjo	293	23	memory	memory	NN
cord-298458-p7rvupjo	293	24	CD8	CD8	NNP
cord-298458-p7rvupjo	293	25	T	T	NNP
cord-298458-p7rvupjo	293	26	cells	cell	NNS
cord-298458-p7rvupjo	293	27	provide	provide	VBP
cord-298458-p7rvupjo	293	28	substantial	substantial	JJ
cord-298458-p7rvupjo	293	29	protection	protection	NN
cord-298458-p7rvupjo	293	30	from	from	IN
cord-298458-p7rvupjo	293	31	lethal	lethal	JJ
cord-298458-p7rvupjo	293	32	severe	severe	JJ
cord-298458-p7rvupjo	293	33	acute	acute	JJ
cord-298458-p7rvupjo	293	34	respiratory	respiratory	JJ
cord-298458-p7rvupjo	293	35	syndrome	syndrome	NN
cord-298458-p7rvupjo	293	36	coronavirus	coronavirus	NN
cord-298458-p7rvupjo	293	37	infection	infection	NN
cord-298458-p7rvupjo	293	38	Memory	Memory	NNP
cord-298458-p7rvupjo	293	39	CD8	CD8	NNP
cord-298458-p7rvupjo	293	40	T	T	NNP
cord-298458-p7rvupjo	293	41	cells	cell	NNS
cord-298458-p7rvupjo	293	42	mediate	mediate	VBP
cord-298458-p7rvupjo	293	43	severe	severe	JJ
cord-298458-p7rvupjo	293	44	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	293	45	following	follow	VBG
cord-298458-p7rvupjo	293	46	respiratory	respiratory	JJ
cord-298458-p7rvupjo	293	47	syncytial	syncytial	JJ
cord-298458-p7rvupjo	293	48	virus	virus	NN
cord-298458-p7rvupjo	293	49	infection	infection	NN
cord-298458-p7rvupjo	293	50	Central	central	JJ
cord-298458-p7rvupjo	293	51	role	role	NN
cord-298458-p7rvupjo	293	52	of	of	IN
cord-298458-p7rvupjo	293	53	dendritic	dendritic	JJ
cord-298458-p7rvupjo	293	54	cells	cell	NNS
cord-298458-p7rvupjo	293	55	in	in	IN
cord-298458-p7rvupjo	293	56	shaping	shape	VBG
cord-298458-p7rvupjo	293	57	the	the	DT
cord-298458-p7rvupjo	293	58	adaptive	adaptive	JJ
cord-298458-p7rvupjo	293	59	immune	immune	JJ
cord-298458-p7rvupjo	293	60	response	response	NN
cord-298458-p7rvupjo	293	61	during	during	IN
cord-298458-p7rvupjo	293	62	respiratory	respiratory	JJ
cord-298458-p7rvupjo	293	63	syncytial	syncytial	JJ
cord-298458-p7rvupjo	293	64	virus	virus	NN
cord-298458-p7rvupjo	293	65	infection	infection	NN
cord-298458-p7rvupjo	293	66	Differential	differential	JJ
cord-298458-p7rvupjo	293	67	roles	role	NNS
cord-298458-p7rvupjo	293	68	of	of	IN
cord-298458-p7rvupjo	293	69	lung	lung	NN
cord-298458-p7rvupjo	293	70	dendritic	dendritic	JJ
cord-298458-p7rvupjo	293	71	cell	cell	NN
cord-298458-p7rvupjo	293	72	subsets	subset	NNS
cord-298458-p7rvupjo	293	73	against	against	IN
cord-298458-p7rvupjo	293	74	respiratory	respiratory	JJ
cord-298458-p7rvupjo	293	75	virus	virus	NN
cord-298458-p7rvupjo	293	76	infection	infection	NN
cord-298458-p7rvupjo	294	1	The	the	DT
cord-298458-p7rvupjo	294	2	effector	effector	NN
cord-298458-p7rvupjo	294	3	T	t	NN
cord-298458-p7rvupjo	294	4	cell	cell	NN
cord-298458-p7rvupjo	294	5	response	response	NN
cord-298458-p7rvupjo	294	6	to	to	IN
cord-298458-p7rvupjo	294	7	influenza	influenza	NN
cord-298458-p7rvupjo	294	8	infection	infection	NN
cord-298458-p7rvupjo	294	9	Visualization	visualization	NN
cord-298458-p7rvupjo	294	10	and	and	CC
cord-298458-p7rvupjo	294	11	characterization	characterization	NN
cord-298458-p7rvupjo	294	12	of	of	IN
cord-298458-p7rvupjo	294	13	respiratory	respiratory	JJ
cord-298458-p7rvupjo	294	14	syncytial	syncytial	JJ
cord-298458-p7rvupjo	294	15	virus	virus	NN
cord-298458-p7rvupjo	294	16	F	f	NN
cord-298458-p7rvupjo	294	17	-	-	HYPH
cord-298458-p7rvupjo	294	18	specific	specific	JJ
cord-298458-p7rvupjo	294	19	CD8(+	CD8(+	NNS
cord-298458-p7rvupjo	294	20	)	)	-RRB-
cord-298458-p7rvupjo	294	21	T	t	NN
cord-298458-p7rvupjo	294	22	cells	cell	NNS
cord-298458-p7rvupjo	294	23	during	during	IN
cord-298458-p7rvupjo	294	24	experimental	experimental	JJ
cord-298458-p7rvupjo	294	25	virus	virus	NN
cord-298458-p7rvupjo	294	26	infection	infection	NN
cord-298458-p7rvupjo	294	27	Characterization	characterization	NN
cord-298458-p7rvupjo	294	28	of	of	IN
cord-298458-p7rvupjo	294	29	the	the	DT
cord-298458-p7rvupjo	294	30	CD8	CD8	NNP
cord-298458-p7rvupjo	294	31	+	+	CC
cord-298458-p7rvupjo	295	1	T	T	NNP
cord-298458-p7rvupjo	295	2	cell	cell	NN
cord-298458-p7rvupjo	295	3	responses	response	NNS
cord-298458-p7rvupjo	295	4	directed	direct	VBN
cord-298458-p7rvupjo	295	5	against	against	IN
cord-298458-p7rvupjo	295	6	respiratory	respiratory	JJ
cord-298458-p7rvupjo	295	7	syncytial	syncytial	JJ
cord-298458-p7rvupjo	295	8	virus	virus	NN
cord-298458-p7rvupjo	295	9	during	during	IN
cord-298458-p7rvupjo	295	10	primary	primary	JJ
cord-298458-p7rvupjo	295	11	and	and	CC
cord-298458-p7rvupjo	295	12	secondary	secondary	JJ
cord-298458-p7rvupjo	295	13	infection	infection	NN
cord-298458-p7rvupjo	295	14	in	in	IN
cord-298458-p7rvupjo	295	15	C57BL/6	C57BL/6	NNP
cord-298458-p7rvupjo	295	16	mice	mouse	NNS
cord-298458-p7rvupjo	295	17	Regulatory	Regulatory	NNP
cord-298458-p7rvupjo	295	18	T	T	NNP
cord-298458-p7rvupjo	295	19	cells	cell	NNS
cord-298458-p7rvupjo	295	20	promote	promote	VBP
cord-298458-p7rvupjo	295	21	early	early	JJ
cord-298458-p7rvupjo	295	22	influx	influx	NN
cord-298458-p7rvupjo	295	23	of	of	IN
cord-298458-p7rvupjo	295	24	CD8	CD8	NNP
cord-298458-p7rvupjo	295	25	+	+	CC
cord-298458-p7rvupjo	295	26	T	T	NNP
cord-298458-p7rvupjo	295	27	cells	cell	NNS
cord-298458-p7rvupjo	295	28	in	in	IN
cord-298458-p7rvupjo	295	29	the	the	DT
cord-298458-p7rvupjo	295	30	lungs	lung	NNS
cord-298458-p7rvupjo	295	31	of	of	IN
cord-298458-p7rvupjo	295	32	respiratory	respiratory	JJ
cord-298458-p7rvupjo	295	33	syncytial	syncytial	JJ
cord-298458-p7rvupjo	295	34	virus	virus	NN
cord-298458-p7rvupjo	295	35	-	-	HYPH
cord-298458-p7rvupjo	295	36	infected	infect	VBN
cord-298458-p7rvupjo	295	37	mice	mouse	NNS
cord-298458-p7rvupjo	295	38	and	and	CC
cord-298458-p7rvupjo	295	39	diminish	diminish	VB
cord-298458-p7rvupjo	295	40	immunodominance	immunodominance	NN
cord-298458-p7rvupjo	295	41	disparities	disparity	NNS
cord-298458-p7rvupjo	296	1	The	the	DT
cord-298458-p7rvupjo	296	2	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	296	3	localization	localization	NN
cord-298458-p7rvupjo	296	4	of	of	IN
cord-298458-p7rvupjo	296	5	virus	virus	NN
cord-298458-p7rvupjo	296	6	-	-	HYPH
cord-298458-p7rvupjo	296	7	specific	specific	JJ
cord-298458-p7rvupjo	296	8	T	t	NN
cord-298458-p7rvupjo	296	9	lymphocytes	lymphocyte	NNS
cord-298458-p7rvupjo	296	10	is	be	VBZ
cord-298458-p7rvupjo	296	11	governed	govern	VBN
cord-298458-p7rvupjo	296	12	by	by	IN
cord-298458-p7rvupjo	296	13	the	the	DT
cord-298458-p7rvupjo	296	14	tissue	tissue	NN
cord-298458-p7rvupjo	296	15	tropism	tropism	NN
cord-298458-p7rvupjo	296	16	of	of	IN
cord-298458-p7rvupjo	296	17	infection	infection	NN
cord-298458-p7rvupjo	296	18	Virus	virus	NN
cord-298458-p7rvupjo	296	19	-	-	HYPH
cord-298458-p7rvupjo	296	20	specific	specific	JJ
cord-298458-p7rvupjo	296	21	CD8	CD8	NNP
cord-298458-p7rvupjo	296	22	+	+	CC
cord-298458-p7rvupjo	296	23	T	t	NN
cord-298458-p7rvupjo	296	24	cells	cell	NNS
cord-298458-p7rvupjo	296	25	in	in	IN
cord-298458-p7rvupjo	296	26	primary	primary	JJ
cord-298458-p7rvupjo	296	27	and	and	CC
cord-298458-p7rvupjo	296	28	secondary	secondary	JJ
cord-298458-p7rvupjo	296	29	influenza	influenza	NN
cord-298458-p7rvupjo	296	30	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	297	1	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	297	2	syncytial	syncytial	NN
cord-298458-p7rvupjo	298	1	virus	virus	NN
cord-298458-p7rvupjo	298	2	-	-	HYPH
cord-298458-p7rvupjo	298	3	specific	specific	JJ
cord-298458-p7rvupjo	298	4	CD8	CD8	NNP
cord-298458-p7rvupjo	298	5	+	+	CC
cord-298458-p7rvupjo	298	6	memory	memory	NN
cord-298458-p7rvupjo	298	7	T	T	NNP
cord-298458-p7rvupjo	298	8	cell	cell	NN
cord-298458-p7rvupjo	298	9	responses	response	NNS
cord-298458-p7rvupjo	298	10	in	in	IN
cord-298458-p7rvupjo	298	11	elderly	elderly	JJ
cord-298458-p7rvupjo	298	12	persons	person	NNS
cord-298458-p7rvupjo	298	13	Nonspecific	nonspecific	JJ
cord-298458-p7rvupjo	298	14	recruitment	recruitment	NN
cord-298458-p7rvupjo	298	15	of	of	IN
cord-298458-p7rvupjo	298	16	memory	memory	NN
cord-298458-p7rvupjo	298	17	CD8	CD8	NNP
cord-298458-p7rvupjo	298	18	+	+	CC
cord-298458-p7rvupjo	298	19	T	T	NNP
cord-298458-p7rvupjo	298	20	cells	cell	NNS
cord-298458-p7rvupjo	298	21	to	to	IN
cord-298458-p7rvupjo	298	22	the	the	DT
cord-298458-p7rvupjo	298	23	lung	lung	NN
cord-298458-p7rvupjo	298	24	airways	airway	NNS
cord-298458-p7rvupjo	298	25	during	during	IN
cord-298458-p7rvupjo	298	26	respiratory	respiratory	JJ
cord-298458-p7rvupjo	298	27	virus	virus	NN
cord-298458-p7rvupjo	298	28	infections	infection	NNS
cord-298458-p7rvupjo	299	1	The	the	DT
cord-298458-p7rvupjo	299	2	chemokine	chemokine	NN
cord-298458-p7rvupjo	299	3	receptor	receptor	NN
cord-298458-p7rvupjo	299	4	CCR5	CCR5	NNP
cord-298458-p7rvupjo	299	5	plays	play	VBZ
cord-298458-p7rvupjo	299	6	a	a	DT
cord-298458-p7rvupjo	299	7	key	key	JJ
cord-298458-p7rvupjo	299	8	role	role	NN
cord-298458-p7rvupjo	299	9	in	in	IN
cord-298458-p7rvupjo	299	10	the	the	DT
cord-298458-p7rvupjo	299	11	early	early	JJ
cord-298458-p7rvupjo	299	12	memory	memory	NN
cord-298458-p7rvupjo	299	13	CD8	CD8	NNP
cord-298458-p7rvupjo	299	14	+	+	CC
cord-298458-p7rvupjo	299	15	T	T	NNP
cord-298458-p7rvupjo	299	16	cell	cell	NN
cord-298458-p7rvupjo	299	17	response	response	NN
cord-298458-p7rvupjo	299	18	to	to	IN
cord-298458-p7rvupjo	299	19	respiratory	respiratory	JJ
cord-298458-p7rvupjo	299	20	virus	virus	NN
cord-298458-p7rvupjo	299	21	infections	infection	NNS
cord-298458-p7rvupjo	300	1	Airway	airway	NN
cord-298458-p7rvupjo	300	2	-	-	HYPH
cord-298458-p7rvupjo	300	3	resident	resident	NN
cord-298458-p7rvupjo	300	4	memory	memory	NN
cord-298458-p7rvupjo	300	5	CD8	CD8	NNP
cord-298458-p7rvupjo	300	6	T	T	NNP
cord-298458-p7rvupjo	300	7	cells	cell	NNS
cord-298458-p7rvupjo	300	8	provide	provide	VBP
cord-298458-p7rvupjo	300	9	antigen	antigen	NN
cord-298458-p7rvupjo	300	10	-	-	HYPH
cord-298458-p7rvupjo	300	11	specific	specific	JJ
cord-298458-p7rvupjo	300	12	protection	protection	NN
cord-298458-p7rvupjo	300	13	against	against	IN
cord-298458-p7rvupjo	300	14	respiratory	respiratory	JJ
cord-298458-p7rvupjo	300	15	virus	virus	NN
cord-298458-p7rvupjo	300	16	challenge	challenge	NN
cord-298458-p7rvupjo	300	17	through	through	IN
cord-298458-p7rvupjo	300	18	rapid	rapid	JJ
cord-298458-p7rvupjo	300	19	IFN	IFN	NNP
cord-298458-p7rvupjo	300	20	-	-	HYPH
cord-298458-p7rvupjo	300	21	gamma	gamma	NN
cord-298458-p7rvupjo	300	22	production	production	NN
cord-298458-p7rvupjo	300	23	Cutting	cutting	NN
cord-298458-p7rvupjo	300	24	edge	edge	NN
cord-298458-p7rvupjo	300	25	:	:	:
cord-298458-p7rvupjo	300	26	effector	effector	NN
cord-298458-p7rvupjo	300	27	memory	memory	NN
cord-298458-p7rvupjo	300	28	CD8	CD8	NNP
cord-298458-p7rvupjo	300	29	+	+	CC
cord-298458-p7rvupjo	300	30	T	T	NNP
cord-298458-p7rvupjo	300	31	cells	cell	NNS
cord-298458-p7rvupjo	300	32	in	in	IN
cord-298458-p7rvupjo	300	33	the	the	DT
cord-298458-p7rvupjo	300	34	lung	lung	NN
cord-298458-p7rvupjo	300	35	airways	airways	NNPS
cord-298458-p7rvupjo	300	36	retain	retain	VBP
cord-298458-p7rvupjo	300	37	the	the	DT
cord-298458-p7rvupjo	300	38	potential	potential	NN
cord-298458-p7rvupjo	300	39	to	to	TO
cord-298458-p7rvupjo	300	40	mediate	mediate	VB
cord-298458-p7rvupjo	300	41	recall	recall	NN
cord-298458-p7rvupjo	300	42	responses	response	NNS
cord-298458-p7rvupjo	300	43	Type	type	NN
cord-298458-p7rvupjo	301	1	I	-PRON-	PRP
cord-298458-p7rvupjo	301	2	interferons	interferon	NNS
cord-298458-p7rvupjo	301	3	regulate	regulate	VBP
cord-298458-p7rvupjo	301	4	cytolytic	cytolytic	JJ
cord-298458-p7rvupjo	301	5	activity	activity	NN
cord-298458-p7rvupjo	301	6	of	of	IN
cord-298458-p7rvupjo	301	7	memory	memory	NN
cord-298458-p7rvupjo	302	1	CD8	CD8	NNP
cord-298458-p7rvupjo	302	2	+	+	CC
cord-298458-p7rvupjo	302	3	T	T	NNP
cord-298458-p7rvupjo	302	4	cells	cell	NNS
cord-298458-p7rvupjo	302	5	in	in	IN
cord-298458-p7rvupjo	302	6	the	the	DT
cord-298458-p7rvupjo	302	7	lung	lung	NN
cord-298458-p7rvupjo	302	8	airways	airway	NNS
cord-298458-p7rvupjo	302	9	during	during	IN
cord-298458-p7rvupjo	302	10	respiratory	respiratory	JJ
cord-298458-p7rvupjo	302	11	virus	virus	NN
cord-298458-p7rvupjo	302	12	challenge	challenge	NN
cord-298458-p7rvupjo	303	1	The	the	DT
cord-298458-p7rvupjo	303	2	who	who	WP
cord-298458-p7rvupjo	303	3	's	be	VBZ
cord-298458-p7rvupjo	303	4	who	who	WP
cord-298458-p7rvupjo	303	5	of	of	IN
cord-298458-p7rvupjo	303	6	T	t	NN
cord-298458-p7rvupjo	303	7	-	-	HYPH
cord-298458-p7rvupjo	303	8	cell	cell	NN
cord-298458-p7rvupjo	303	9	differentiation	differentiation	NN
cord-298458-p7rvupjo	303	10	:	:	:
cord-298458-p7rvupjo	303	11	human	human	JJ
cord-298458-p7rvupjo	303	12	memory	memory	NN
cord-298458-p7rvupjo	303	13	T	t	NN
cord-298458-p7rvupjo	303	14	-	-	HYPH
cord-298458-p7rvupjo	303	15	cell	cell	NN
cord-298458-p7rvupjo	303	16	subsets	subset	NNS
cord-298458-p7rvupjo	303	17	Memory	Memory	NNP
cord-298458-p7rvupjo	303	18	T	T	NNP
cord-298458-p7rvupjo	303	19	cells	cell	NNS
cord-298458-p7rvupjo	303	20	in	in	IN
cord-298458-p7rvupjo	303	21	nonlymphoid	nonlymphoid	JJ
cord-298458-p7rvupjo	303	22	tissue	tissue	NN
cord-298458-p7rvupjo	303	23	that	that	WDT
cord-298458-p7rvupjo	303	24	provide	provide	VBP
cord-298458-p7rvupjo	303	25	enhanced	enhanced	JJ
cord-298458-p7rvupjo	303	26	local	local	JJ
cord-298458-p7rvupjo	303	27	immunity	immunity	NN
cord-298458-p7rvupjo	303	28	during	during	IN
cord-298458-p7rvupjo	303	29	infection	infection	NN
cord-298458-p7rvupjo	303	30	with	with	IN
cord-298458-p7rvupjo	303	31	herpes	herpes	NN
cord-298458-p7rvupjo	303	32	simplex	simplex	NNP
cord-298458-p7rvupjo	303	33	virus	virus	NN
cord-298458-p7rvupjo	303	34	Lung	lung	NN
cord-298458-p7rvupjo	303	35	niches	niche	NNS
cord-298458-p7rvupjo	303	36	for	for	IN
cord-298458-p7rvupjo	303	37	the	the	DT
cord-298458-p7rvupjo	303	38	generation	generation	NN
cord-298458-p7rvupjo	303	39	and	and	CC
cord-298458-p7rvupjo	303	40	maintenance	maintenance	NN
cord-298458-p7rvupjo	303	41	of	of	IN
cord-298458-p7rvupjo	303	42	tissue	tissue	NN
cord-298458-p7rvupjo	303	43	-	-	HYPH
cord-298458-p7rvupjo	303	44	resident	resident	NN
cord-298458-p7rvupjo	303	45	memory	memory	NN
cord-298458-p7rvupjo	303	46	T	T	NNP
cord-298458-p7rvupjo	303	47	cells	cell	NNS
cord-298458-p7rvupjo	303	48	Lung	lung	NN
cord-298458-p7rvupjo	303	49	-	-	HYPH
cord-298458-p7rvupjo	303	50	resident	resident	NN
cord-298458-p7rvupjo	303	51	memory	memory	NN
cord-298458-p7rvupjo	303	52	CD8	CD8	NNP
cord-298458-p7rvupjo	303	53	T	T	NNP
cord-298458-p7rvupjo	303	54	cells	cell	NNS
cord-298458-p7rvupjo	303	55	(	(	-LRB-
cord-298458-p7rvupjo	303	56	TRM	TRM	NNP
cord-298458-p7rvupjo	303	57	)	)	-RRB-
cord-298458-p7rvupjo	303	58	are	be	VBP
cord-298458-p7rvupjo	303	59	indispensable	indispensable	JJ
cord-298458-p7rvupjo	303	60	for	for	IN
cord-298458-p7rvupjo	303	61	optimal	optimal	JJ
cord-298458-p7rvupjo	303	62	cross	cross	NN
cord-298458-p7rvupjo	303	63	-	-	NN
cord-298458-p7rvupjo	303	64	protection	protection	NN
cord-298458-p7rvupjo	303	65	against	against	IN
cord-298458-p7rvupjo	303	66	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	303	67	virus	virus	NN
cord-298458-p7rvupjo	303	68	infection	infection	NN
cord-298458-p7rvupjo	303	69	Specific	specific	JJ
cord-298458-p7rvupjo	303	70	niches	niche	NNS
cord-298458-p7rvupjo	303	71	for	for	IN
cord-298458-p7rvupjo	303	72	lung	lung	NN
cord-298458-p7rvupjo	303	73	-	-	HYPH
cord-298458-p7rvupjo	303	74	resident	resident	NN
cord-298458-p7rvupjo	303	75	memory	memory	NN
cord-298458-p7rvupjo	303	76	CD8	CD8	NNP
cord-298458-p7rvupjo	303	77	+	+	CC
cord-298458-p7rvupjo	303	78	T	T	NNP
cord-298458-p7rvupjo	303	79	cells	cell	NNS
cord-298458-p7rvupjo	303	80	at	at	IN
cord-298458-p7rvupjo	303	81	the	the	DT
cord-298458-p7rvupjo	303	82	site	site	NN
cord-298458-p7rvupjo	303	83	of	of	IN
cord-298458-p7rvupjo	303	84	tissue	tissue	NN
cord-298458-p7rvupjo	303	85	regeneration	regeneration	NN
cord-298458-p7rvupjo	303	86	enable	enable	VBP
cord-298458-p7rvupjo	303	87	CD69-independent	cd69-independent	CD
cord-298458-p7rvupjo	304	1	maintenance	maintenance	NN
cord-298458-p7rvupjo	304	2	Long	long	JJ
cord-298458-p7rvupjo	304	3	-	-	HYPH
cord-298458-p7rvupjo	304	4	term	term	NN
cord-298458-p7rvupjo	304	5	persistence	persistence	NN
cord-298458-p7rvupjo	304	6	and	and	CC
cord-298458-p7rvupjo	304	7	reactivation	reactivation	NN
cord-298458-p7rvupjo	304	8	of	of	IN
cord-298458-p7rvupjo	304	9	T	T	NNP
cord-298458-p7rvupjo	304	10	cell	cell	NN
cord-298458-p7rvupjo	304	11	memory	memory	NN
cord-298458-p7rvupjo	304	12	in	in	IN
cord-298458-p7rvupjo	304	13	the	the	DT
cord-298458-p7rvupjo	304	14	lung	lung	NN
cord-298458-p7rvupjo	304	15	of	of	IN
cord-298458-p7rvupjo	304	16	mice	mouse	NNS
cord-298458-p7rvupjo	304	17	infected	infect	VBN
cord-298458-p7rvupjo	304	18	with	with	IN
cord-298458-p7rvupjo	304	19	respiratory	respiratory	JJ
cord-298458-p7rvupjo	304	20	syncytial	syncytial	JJ
cord-298458-p7rvupjo	304	21	virus	virus	NN
cord-298458-p7rvupjo	304	22	Long	long	JJ
cord-298458-p7rvupjo	304	23	-	-	HYPH
cord-298458-p7rvupjo	304	24	term	term	NN
cord-298458-p7rvupjo	304	25	maintenance	maintenance	NN
cord-298458-p7rvupjo	304	26	of	of	IN
cord-298458-p7rvupjo	304	27	virus	virus	NN
cord-298458-p7rvupjo	304	28	-	-	HYPH
cord-298458-p7rvupjo	304	29	specific	specific	JJ
cord-298458-p7rvupjo	304	30	effector	effector	NN
cord-298458-p7rvupjo	304	31	memory	memory	NN
cord-298458-p7rvupjo	304	32	CD8	CD8	NNP
cord-298458-p7rvupjo	304	33	+	+	CC
cord-298458-p7rvupjo	304	34	T	T	NNP
cord-298458-p7rvupjo	304	35	cells	cell	NNS
cord-298458-p7rvupjo	304	36	in	in	IN
cord-298458-p7rvupjo	304	37	the	the	DT
cord-298458-p7rvupjo	304	38	lung	lung	NN
cord-298458-p7rvupjo	304	39	airways	airways	NNP
cord-298458-p7rvupjo	304	40	depends	depend	VBZ
cord-298458-p7rvupjo	304	41	on	on	IN
cord-298458-p7rvupjo	304	42	proliferation	proliferation	NN
cord-298458-p7rvupjo	304	43	Memory	memory	NN
cord-298458-p7rvupjo	304	44	T	T	NNP
cord-298458-p7rvupjo	304	45	cell	cell	NN
cord-298458-p7rvupjo	304	46	populations	population	NNS
cord-298458-p7rvupjo	304	47	in	in	IN
cord-298458-p7rvupjo	304	48	the	the	DT
cord-298458-p7rvupjo	304	49	lung	lung	NN
cord-298458-p7rvupjo	304	50	airways	airway	NNS
cord-298458-p7rvupjo	304	51	are	be	VBP
cord-298458-p7rvupjo	304	52	maintained	maintain	VBN
cord-298458-p7rvupjo	304	53	by	by	IN
cord-298458-p7rvupjo	304	54	continual	continual	JJ
cord-298458-p7rvupjo	304	55	recruitment	recruitment	NN
cord-298458-p7rvupjo	304	56	Cutting	cutting	NN
cord-298458-p7rvupjo	304	57	edge	edge	NN
cord-298458-p7rvupjo	304	58	:	:	:
cord-298458-p7rvupjo	304	59	antigen	antigen	NN
cord-298458-p7rvupjo	304	60	is	be	VBZ
cord-298458-p7rvupjo	304	61	not	not	RB
cord-298458-p7rvupjo	304	62	required	require	VBN
cord-298458-p7rvupjo	304	63	for	for	IN
cord-298458-p7rvupjo	304	64	the	the	DT
cord-298458-p7rvupjo	304	65	activation	activation	NN
cord-298458-p7rvupjo	304	66	and	and	CC
cord-298458-p7rvupjo	304	67	maintenance	maintenance	NN
cord-298458-p7rvupjo	304	68	of	of	IN
cord-298458-p7rvupjo	304	69	virus	virus	NN
cord-298458-p7rvupjo	304	70	-	-	HYPH
cord-298458-p7rvupjo	304	71	specific	specific	JJ
cord-298458-p7rvupjo	304	72	memory	memory	NN
cord-298458-p7rvupjo	304	73	CD8	CD8	NNP
cord-298458-p7rvupjo	304	74	+	+	CC
cord-298458-p7rvupjo	304	75	T	T	NNP
cord-298458-p7rvupjo	304	76	cells	cell	NNS
cord-298458-p7rvupjo	304	77	in	in	IN
cord-298458-p7rvupjo	304	78	the	the	DT
cord-298458-p7rvupjo	304	79	lung	lung	NN
cord-298458-p7rvupjo	304	80	airways	airways	NNPS
cord-298458-p7rvupjo	305	1	In	in	IN
cord-298458-p7rvupjo	305	2	situ	situ	NN
cord-298458-p7rvupjo	305	3	imaging	imaging	NN
cord-298458-p7rvupjo	305	4	reveals	reveal	VBZ
cord-298458-p7rvupjo	305	5	different	different	JJ
cord-298458-p7rvupjo	305	6	responses	response	NNS
cord-298458-p7rvupjo	305	7	by	by	IN
cord-298458-p7rvupjo	305	8	naive	naive	JJ
cord-298458-p7rvupjo	305	9	and	and	CC
cord-298458-p7rvupjo	305	10	memory	memory	NN
cord-298458-p7rvupjo	305	11	CD8	CD8	NNP
cord-298458-p7rvupjo	305	12	T	T	NNP
cord-298458-p7rvupjo	305	13	cells	cell	NNS
cord-298458-p7rvupjo	305	14	to	to	IN
cord-298458-p7rvupjo	305	15	late	late	JJ
cord-298458-p7rvupjo	305	16	antigen	antigen	NN
cord-298458-p7rvupjo	305	17	presentation	presentation	NN
cord-298458-p7rvupjo	305	18	by	by	IN
cord-298458-p7rvupjo	305	19	lymph	lymph	NN
cord-298458-p7rvupjo	305	20	node	node	NN
cord-298458-p7rvupjo	305	21	DC	DC	NNP
cord-298458-p7rvupjo	305	22	after	after	IN
cord-298458-p7rvupjo	305	23	influenza	influenza	NN
cord-298458-p7rvupjo	305	24	virus	virus	NN
cord-298458-p7rvupjo	305	25	infection	infection	NN
cord-298458-p7rvupjo	306	1	Smad4	Smad4	NNP
cord-298458-p7rvupjo	306	2	promotes	promote	VBZ
cord-298458-p7rvupjo	306	3	differentiation	differentiation	NN
cord-298458-p7rvupjo	306	4	of	of	IN
cord-298458-p7rvupjo	306	5	effector	effector	NN
cord-298458-p7rvupjo	306	6	and	and	CC
cord-298458-p7rvupjo	306	7	circulating	circulate	VBG
cord-298458-p7rvupjo	306	8	memory	memory	NN
cord-298458-p7rvupjo	306	9	CD8	CD8	NNP
cord-298458-p7rvupjo	306	10	T	T	NNP
cord-298458-p7rvupjo	306	11	cells	cell	NNS
cord-298458-p7rvupjo	306	12	but	but	CC
cord-298458-p7rvupjo	306	13	is	be	VBZ
cord-298458-p7rvupjo	306	14	dispensable	dispensable	JJ
cord-298458-p7rvupjo	306	15	for	for	IN
cord-298458-p7rvupjo	306	16	tissue	tissue	NN
cord-298458-p7rvupjo	306	17	-	-	HYPH
cord-298458-p7rvupjo	306	18	resident	resident	NN
cord-298458-p7rvupjo	306	19	memory	memory	NN
cord-298458-p7rvupjo	306	20	CD8	CD8	NNP
cord-298458-p7rvupjo	306	21	T	T	NNP
cord-298458-p7rvupjo	306	22	cells	cell	NNS
cord-298458-p7rvupjo	307	1	Environmental	environmental	JJ
cord-298458-p7rvupjo	307	2	and	and	CC
cord-298458-p7rvupjo	307	3	antigen	antigen	NN
cord-298458-p7rvupjo	307	4	receptor	receptor	NN
cord-298458-p7rvupjo	307	5	-	-	HYPH
cord-298458-p7rvupjo	307	6	derived	derive	VBN
cord-298458-p7rvupjo	307	7	signals	signal	NNS
cord-298458-p7rvupjo	307	8	support	support	VBP
cord-298458-p7rvupjo	307	9	sustained	sustained	JJ
cord-298458-p7rvupjo	307	10	surveillance	surveillance	NN
cord-298458-p7rvupjo	307	11	of	of	IN
cord-298458-p7rvupjo	307	12	the	the	DT
cord-298458-p7rvupjo	307	13	lungs	lung	NNS
cord-298458-p7rvupjo	307	14	by	by	IN
cord-298458-p7rvupjo	307	15	pathogen	pathogen	NN
cord-298458-p7rvupjo	307	16	-	-	HYPH
cord-298458-p7rvupjo	307	17	specific	specific	JJ
cord-298458-p7rvupjo	307	18	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	307	19	T	t	NN
cord-298458-p7rvupjo	307	20	lymphocytes	lymphocyte	NNS
cord-298458-p7rvupjo	307	21	Enhanced	enhance	VBN
cord-298458-p7rvupjo	307	22	survival	survival	NN
cord-298458-p7rvupjo	307	23	of	of	IN
cord-298458-p7rvupjo	307	24	lung	lung	NN
cord-298458-p7rvupjo	307	25	tissue	tissue	NN
cord-298458-p7rvupjo	307	26	-	-	HYPH
cord-298458-p7rvupjo	307	27	resident	resident	NN
cord-298458-p7rvupjo	307	28	memory	memory	NN
cord-298458-p7rvupjo	307	29	CD8	CD8	NNP
cord-298458-p7rvupjo	307	30	+	+	CC
cord-298458-p7rvupjo	307	31	T	T	NNP
cord-298458-p7rvupjo	307	32	cells	cell	NNS
cord-298458-p7rvupjo	307	33	during	during	IN
cord-298458-p7rvupjo	307	34	infection	infection	NN
cord-298458-p7rvupjo	307	35	with	with	IN
cord-298458-p7rvupjo	307	36	influenza	influenza	NN
cord-298458-p7rvupjo	307	37	virus	virus	NN
cord-298458-p7rvupjo	307	38	due	due	IN
cord-298458-p7rvupjo	307	39	to	to	IN
cord-298458-p7rvupjo	307	40	selective	selective	JJ
cord-298458-p7rvupjo	307	41	expression	expression	NN
cord-298458-p7rvupjo	307	42	of	of	IN
cord-298458-p7rvupjo	307	43	IFITM3	IFITM3	NNP
cord-298458-p7rvupjo	307	44	Airway	Airway	NNP
cord-298458-p7rvupjo	307	45	T	T	NNP
cord-298458-p7rvupjo	307	46	cells	cell	NNS
cord-298458-p7rvupjo	307	47	protect	protect	VBP
cord-298458-p7rvupjo	307	48	against	against	IN
cord-298458-p7rvupjo	307	49	RSV	RSV	NNP
cord-298458-p7rvupjo	307	50	infection	infection	NN
cord-298458-p7rvupjo	307	51	in	in	IN
cord-298458-p7rvupjo	307	52	the	the	DT
cord-298458-p7rvupjo	307	53	absence	absence	NN
cord-298458-p7rvupjo	307	54	of	of	IN
cord-298458-p7rvupjo	307	55	antibody	antibody	NN
cord-298458-p7rvupjo	307	56	Vaccine	vaccine	NN
cord-298458-p7rvupjo	307	57	-	-	HYPH
cord-298458-p7rvupjo	307	58	generated	generate	VBN
cord-298458-p7rvupjo	307	59	lung	lung	NN
cord-298458-p7rvupjo	307	60	tissue	tissue	NN
cord-298458-p7rvupjo	307	61	-	-	HYPH
cord-298458-p7rvupjo	307	62	resident	resident	NN
cord-298458-p7rvupjo	307	63	memory	memory	NN
cord-298458-p7rvupjo	307	64	T	T	NNP
cord-298458-p7rvupjo	307	65	cells	cell	NNS
cord-298458-p7rvupjo	307	66	provide	provide	VBP
cord-298458-p7rvupjo	307	67	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	307	68	protection	protection	NN
cord-298458-p7rvupjo	307	69	to	to	IN
cord-298458-p7rvupjo	307	70	influenza	influenza	NN
cord-298458-p7rvupjo	307	71	infection	infection	NN
cord-298458-p7rvupjo	308	1	Intranasal	Intranasal	NNP
cord-298458-p7rvupjo	308	2	administration	administration	NN
cord-298458-p7rvupjo	308	3	of	of	IN
cord-298458-p7rvupjo	308	4	RSV	RSV	NNP
cord-298458-p7rvupjo	308	5	antigen	antigen	NNP
cord-298458-p7rvupjo	308	6	-	-	HYPH
cord-298458-p7rvupjo	308	7	expressing	express	VBG
cord-298458-p7rvupjo	308	8	MCMV	MCMV	NNP
cord-298458-p7rvupjo	308	9	elicits	elicit	VBZ
cord-298458-p7rvupjo	308	10	robust	robust	JJ
cord-298458-p7rvupjo	308	11	tissue	tissue	NN
cord-298458-p7rvupjo	308	12	-	-	HYPH
cord-298458-p7rvupjo	308	13	resident	resident	NN
cord-298458-p7rvupjo	308	14	effector	effector	NN
cord-298458-p7rvupjo	308	15	and	and	CC
cord-298458-p7rvupjo	308	16	effector	effector	NN
cord-298458-p7rvupjo	308	17	memory	memory	NN
cord-298458-p7rvupjo	308	18	CD8	CD8	NNP
cord-298458-p7rvupjo	308	19	+	+	CC
cord-298458-p7rvupjo	308	20	T	T	NNP
cord-298458-p7rvupjo	308	21	cells	cell	NNS
cord-298458-p7rvupjo	308	22	in	in	IN
cord-298458-p7rvupjo	308	23	the	the	DT
cord-298458-p7rvupjo	308	24	lung	lung	NN
cord-298458-p7rvupjo	308	25	Reduced	reduce	VBN
cord-298458-p7rvupjo	308	26	generation	generation	NN
cord-298458-p7rvupjo	308	27	of	of	IN
cord-298458-p7rvupjo	308	28	lung	lung	NN
cord-298458-p7rvupjo	308	29	tissue	tissue	NN
cord-298458-p7rvupjo	308	30	-	-	HYPH
cord-298458-p7rvupjo	308	31	resident	resident	NN
cord-298458-p7rvupjo	308	32	memory	memory	NN
cord-298458-p7rvupjo	308	33	T	t	NN
cord-298458-p7rvupjo	308	34	cells	cell	NNS
cord-298458-p7rvupjo	308	35	during	during	IN
cord-298458-p7rvupjo	308	36	infancy	infancy	JJ
cord-298458-p7rvupjo	308	37	Dynamics	dynamic	NNS
cord-298458-p7rvupjo	308	38	of	of	IN
cord-298458-p7rvupjo	308	39	influenza	influenza	NN
cord-298458-p7rvupjo	308	40	-	-	HYPH
cord-298458-p7rvupjo	308	41	induced	induce	VBN
cord-298458-p7rvupjo	308	42	lung	lung	NN
cord-298458-p7rvupjo	308	43	-	-	HYPH
cord-298458-p7rvupjo	308	44	resident	resident	NN
cord-298458-p7rvupjo	308	45	memory	memory	NN
cord-298458-p7rvupjo	308	46	T	T	NNP
cord-298458-p7rvupjo	308	47	cells	cell	NNS
cord-298458-p7rvupjo	309	1	underlie	underlie	VBP
cord-298458-p7rvupjo	309	2	waning	wane	VBG
cord-298458-p7rvupjo	309	3	heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	309	4	immunity	immunity	NN
cord-298458-p7rvupjo	309	5	In	in	IN
cord-298458-p7rvupjo	309	6	vivo	vivo	NN
cord-298458-p7rvupjo	309	7	effector	effector	NN
cord-298458-p7rvupjo	309	8	function	function	NN
cord-298458-p7rvupjo	309	9	of	of	IN
cord-298458-p7rvupjo	309	10	influenza	influenza	NN
cord-298458-p7rvupjo	309	11	virus	virus	NN
cord-298458-p7rvupjo	309	12	-	-	HYPH
cord-298458-p7rvupjo	309	13	specific	specific	JJ
cord-298458-p7rvupjo	309	14	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	309	15	T	t	NN
cord-298458-p7rvupjo	309	16	lymphocyte	lymphocyte	NN
cord-298458-p7rvupjo	309	17	clones	clone	NNS
cord-298458-p7rvupjo	309	18	is	be	VBZ
cord-298458-p7rvupjo	309	19	highly	highly	RB
cord-298458-p7rvupjo	309	20	specific	specific	JJ
cord-298458-p7rvupjo	309	21	Cytotoxic	Cytotoxic	NNP
cord-298458-p7rvupjo	309	22	T	t	NN
cord-298458-p7rvupjo	309	23	cells	cell	NNS
cord-298458-p7rvupjo	309	24	clear	clear	JJ
cord-298458-p7rvupjo	309	25	virus	virus	NN
cord-298458-p7rvupjo	309	26	but	but	CC
cord-298458-p7rvupjo	309	27	augment	augment	VB
cord-298458-p7rvupjo	309	28	lung	lung	NN
cord-298458-p7rvupjo	309	29	pathology	pathology	NN
cord-298458-p7rvupjo	309	30	in	in	IN
cord-298458-p7rvupjo	309	31	mice	mouse	NNS
cord-298458-p7rvupjo	309	32	infected	infect	VBN
cord-298458-p7rvupjo	309	33	with	with	IN
cord-298458-p7rvupjo	309	34	respiratory	respiratory	JJ
cord-298458-p7rvupjo	309	35	syncytial	syncytial	JJ
cord-298458-p7rvupjo	309	36	virus	virus	NN
cord-298458-p7rvupjo	309	37	CD4	CD4	NNP
cord-298458-p7rvupjo	309	38	+	+	CC
cord-298458-p7rvupjo	309	39	T	t	NN
cord-298458-p7rvupjo	309	40	cells	cell	NNS
cord-298458-p7rvupjo	309	41	clear	clear	JJ
cord-298458-p7rvupjo	309	42	virus	virus	NN
cord-298458-p7rvupjo	309	43	but	but	CC
cord-298458-p7rvupjo	309	44	augment	augment	VB
cord-298458-p7rvupjo	309	45	disease	disease	NN
cord-298458-p7rvupjo	309	46	in	in	IN
cord-298458-p7rvupjo	309	47	mice	mouse	NNS
cord-298458-p7rvupjo	309	48	infected	infect	VBN
cord-298458-p7rvupjo	309	49	with	with	IN
cord-298458-p7rvupjo	309	50	respiratory	respiratory	JJ
cord-298458-p7rvupjo	309	51	syncytial	syncytial	JJ
cord-298458-p7rvupjo	309	52	virus	virus	NN
cord-298458-p7rvupjo	309	53	.	.	.
cord-298458-p7rvupjo	310	1	Comparison	comparison	NN
cord-298458-p7rvupjo	310	2	with	with	IN
cord-298458-p7rvupjo	310	3	the	the	DT
cord-298458-p7rvupjo	310	4	effects	effect	NNS
cord-298458-p7rvupjo	310	5	of	of	IN
cord-298458-p7rvupjo	310	6	CD8	CD8	NNP
cord-298458-p7rvupjo	310	7	+	+	CC
cord-298458-p7rvupjo	310	8	T	T	NNP
cord-298458-p7rvupjo	310	9	cells	cell	NNS
cord-298458-p7rvupjo	311	1	Distinct	distinct	JJ
cord-298458-p7rvupjo	311	2	types	type	NNS
cord-298458-p7rvupjo	311	3	of	of	IN
cord-298458-p7rvupjo	311	4	lung	lung	NN
cord-298458-p7rvupjo	311	5	disease	disease	NN
cord-298458-p7rvupjo	311	6	caused	cause	VBN
cord-298458-p7rvupjo	311	7	by	by	IN
cord-298458-p7rvupjo	311	8	functional	functional	JJ
cord-298458-p7rvupjo	311	9	subsets	subset	NNS
cord-298458-p7rvupjo	311	10	of	of	IN
cord-298458-p7rvupjo	311	11	antiviral	antiviral	JJ
cord-298458-p7rvupjo	311	12	T	t	NN
cord-298458-p7rvupjo	311	13	cells	cell	NNS
cord-298458-p7rvupjo	312	1	The	the	DT
cord-298458-p7rvupjo	312	2	recovery	recovery	NN
cord-298458-p7rvupjo	312	3	of	of	IN
cord-298458-p7rvupjo	312	4	mice	mouse	NNS
cord-298458-p7rvupjo	312	5	from	from	IN
cord-298458-p7rvupjo	312	6	influenza	influenza	NN
cord-298458-p7rvupjo	312	7	virus	virus	NN
cord-298458-p7rvupjo	312	8	infection	infection	NN
cord-298458-p7rvupjo	312	9	:	:	:
cord-298458-p7rvupjo	312	10	adoptive	adoptive	JJ
cord-298458-p7rvupjo	312	11	transfer	transfer	NN
cord-298458-p7rvupjo	312	12	of	of	IN
cord-298458-p7rvupjo	312	13	immunity	immunity	NN
cord-298458-p7rvupjo	312	14	with	with	IN
cord-298458-p7rvupjo	312	15	immune	immune	JJ
cord-298458-p7rvupjo	312	16	T	t	NN
cord-298458-p7rvupjo	312	17	lymphocytes	lymphocyte	NNS
cord-298458-p7rvupjo	313	1	Transfer	transfer	NN
cord-298458-p7rvupjo	313	2	of	of	IN
cord-298458-p7rvupjo	313	3	specific	specific	JJ
cord-298458-p7rvupjo	313	4	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	313	5	T	t	NN
cord-298458-p7rvupjo	313	6	lymphocytes	lymphocyte	NNS
cord-298458-p7rvupjo	313	7	protects	protect	VBZ
cord-298458-p7rvupjo	313	8	mice	mouse	NNS
cord-298458-p7rvupjo	313	9	inoculated	inoculate	VBN
cord-298458-p7rvupjo	313	10	with	with	IN
cord-298458-p7rvupjo	313	11	influenza	influenza	NN
cord-298458-p7rvupjo	313	12	virus	virus	NN
cord-298458-p7rvupjo	313	13	Recovery	recovery	NN
cord-298458-p7rvupjo	313	14	from	from	IN
cord-298458-p7rvupjo	313	15	a	a	DT
cord-298458-p7rvupjo	313	16	viral	viral	JJ
cord-298458-p7rvupjo	313	17	respiratory	respiratory	JJ
cord-298458-p7rvupjo	313	18	infection	infection	NN
cord-298458-p7rvupjo	313	19	.	.	.
cord-298458-p7rvupjo	314	1	II	II	NNP
cord-298458-p7rvupjo	314	2	.	.	.
cord-298458-p7rvupjo	315	1	Passive	passive	JJ
cord-298458-p7rvupjo	315	2	transfer	transfer	NN
cord-298458-p7rvupjo	315	3	of	of	IN
cord-298458-p7rvupjo	315	4	immune	immune	JJ
cord-298458-p7rvupjo	315	5	spleen	spleen	NN
cord-298458-p7rvupjo	315	6	cells	cell	NNS
cord-298458-p7rvupjo	315	7	to	to	IN
cord-298458-p7rvupjo	315	8	mice	mouse	NNS
cord-298458-p7rvupjo	315	9	with	with	IN
cord-298458-p7rvupjo	315	10	influenza	influenza	NN
cord-298458-p7rvupjo	315	11	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	315	12	Clearance	Clearance	NNP
cord-298458-p7rvupjo	315	13	of	of	IN
cord-298458-p7rvupjo	315	14	persistent	persistent	JJ
cord-298458-p7rvupjo	315	15	respiratory	respiratory	JJ
cord-298458-p7rvupjo	315	16	syncytial	syncytial	JJ
cord-298458-p7rvupjo	315	17	virus	virus	NN
cord-298458-p7rvupjo	315	18	infections	infection	NNS
cord-298458-p7rvupjo	315	19	in	in	IN
cord-298458-p7rvupjo	315	20	immunodeficient	immunodeficient	JJ
cord-298458-p7rvupjo	315	21	mice	mouse	NNS
cord-298458-p7rvupjo	315	22	following	follow	VBG
cord-298458-p7rvupjo	315	23	trans	trans	NNP
cord-298458-p7rvupjo	315	24	fer	fer	NN
cord-298458-p7rvupjo	315	25	of	of	IN
cord-298458-p7rvupjo	315	26	primed	prime	VBN
cord-298458-p7rvupjo	315	27	T	t	NN
cord-298458-p7rvupjo	315	28	cells	cell	NNS
cord-298458-p7rvupjo	315	29	Virus	virus	NN
cord-298458-p7rvupjo	315	30	clearance	clearance	NN
cord-298458-p7rvupjo	315	31	and	and	CC
cord-298458-p7rvupjo	315	32	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	315	33	by	by	IN
cord-298458-p7rvupjo	315	34	CD8(+	CD8(+	NNP
cord-298458-p7rvupjo	315	35	)	)	-RRB-
cord-298458-p7rvupjo	315	36	T	t	NN
cord-298458-p7rvupjo	315	37	cells	cell	NNS
cord-298458-p7rvupjo	315	38	during	during	IN
cord-298458-p7rvupjo	315	39	infection	infection	NN
cord-298458-p7rvupjo	315	40	with	with	IN
cord-298458-p7rvupjo	315	41	respiratory	respiratory	JJ
cord-298458-p7rvupjo	315	42	syncytial	syncytial	JJ
cord-298458-p7rvupjo	315	43	virus	virus	NN
cord-298458-p7rvupjo	315	44	are	be	VBP
cord-298458-p7rvupjo	315	45	mediated	mediate	VBN
cord-298458-p7rvupjo	315	46	by	by	IN
cord-298458-p7rvupjo	315	47	IFN	IFN	NNP
cord-298458-p7rvupjo	315	48	-	-	HYPH
cord-298458-p7rvupjo	315	49	gamma	gamma	NN
cord-298458-p7rvupjo	315	50	Cytotoxic	Cytotoxic	NNP
cord-298458-p7rvupjo	315	51	lymphocytes	lymphocyte	NNS
cord-298458-p7rvupjo	315	52	in	in	IN
cord-298458-p7rvupjo	315	53	the	the	DT
cord-298458-p7rvupjo	315	54	lungs	lung	NNS
cord-298458-p7rvupjo	315	55	of	of	IN
cord-298458-p7rvupjo	315	56	mice	mouse	NNS
cord-298458-p7rvupjo	315	57	infected	infect	VBN
cord-298458-p7rvupjo	315	58	with	with	IN
cord-298458-p7rvupjo	315	59	respiratory	respiratory	JJ
cord-298458-p7rvupjo	315	60	syncytial	syncytial	JJ
cord-298458-p7rvupjo	315	61	virus	virus	NN
cord-298458-p7rvupjo	315	62	Cellular	cellular	JJ
cord-298458-p7rvupjo	315	63	response	response	NN
cord-298458-p7rvupjo	315	64	to	to	IN
cord-298458-p7rvupjo	315	65	respiratory	respiratory	JJ
cord-298458-p7rvupjo	315	66	viruses	virus	NNS
cord-298458-p7rvupjo	315	67	with	with	IN
cord-298458-p7rvupjo	315	68	particular	particular	JJ
cord-298458-p7rvupjo	315	69	reference	reference	NN
cord-298458-p7rvupjo	315	70	to	to	IN
cord-298458-p7rvupjo	315	71	children	child	NNS
cord-298458-p7rvupjo	315	72	with	with	IN
cord-298458-p7rvupjo	315	73	disorders	disorder	NNS
cord-298458-p7rvupjo	315	74	of	of	IN
cord-298458-p7rvupjo	315	75	cell	cell	NN
cord-298458-p7rvupjo	315	76	-	-	HYPH
cord-298458-p7rvupjo	315	77	mediated	mediate	VBN
cord-298458-p7rvupjo	315	78	immunity	immunity	NN
cord-298458-p7rvupjo	315	79	Quantitative	quantitative	JJ
cord-298458-p7rvupjo	315	80	effects	effect	NNS
cord-298458-p7rvupjo	315	81	of	of	IN
cord-298458-p7rvupjo	315	82	palivizumab	palivizumab	NNS
cord-298458-p7rvupjo	315	83	and	and	CC
cord-298458-p7rvupjo	315	84	donor	donor	NN
cord-298458-p7rvupjo	315	85	-	-	HYPH
cord-298458-p7rvupjo	315	86	derived	derive	VBN
cord-298458-p7rvupjo	315	87	T	t	NN
cord-298458-p7rvupjo	315	88	cells	cell	NNS
cord-298458-p7rvupjo	315	89	on	on	IN
cord-298458-p7rvupjo	315	90	chronic	chronic	JJ
cord-298458-p7rvupjo	315	91	respiratory	respiratory	JJ
cord-298458-p7rvupjo	315	92	syncytial	syncytial	JJ
cord-298458-p7rvupjo	315	93	virus	virus	NN
cord-298458-p7rvupjo	315	94	infection	infection	NN
cord-298458-p7rvupjo	315	95	,	,	,
cord-298458-p7rvupjo	315	96	lung	lung	NN
cord-298458-p7rvupjo	315	97	disease	disease	NN
cord-298458-p7rvupjo	315	98	,	,	,
cord-298458-p7rvupjo	315	99	and	and	CC
cord-298458-p7rvupjo	315	100	fusion	fusion	NN
cord-298458-p7rvupjo	315	101	glycoprotein	glycoprotein	NN
cord-298458-p7rvupjo	315	102	amino	amino	NN
cord-298458-p7rvupjo	315	103	acid	acid	NN
cord-298458-p7rvupjo	315	104	sequences	sequence	NNS
cord-298458-p7rvupjo	315	105	in	in	IN
cord-298458-p7rvupjo	315	106	a	a	DT
cord-298458-p7rvupjo	315	107	patient	patient	NN
cord-298458-p7rvupjo	315	108	before	before	IN
cord-298458-p7rvupjo	315	109	and	and	CC
cord-298458-p7rvupjo	315	110	after	after	IN
cord-298458-p7rvupjo	315	111	bone	bone	NN
cord-298458-p7rvupjo	315	112	marrow	marrow	NN
cord-298458-p7rvupjo	315	113	transplantation	transplantation	NN
cord-298458-p7rvupjo	316	1	Cytotoxic	Cytotoxic	NNP
cord-298458-p7rvupjo	316	2	T	t	NN
cord-298458-p7rvupjo	316	3	-	-	HYPH
cord-298458-p7rvupjo	316	4	cell	cell	NN
cord-298458-p7rvupjo	316	5	immunity	immunity	NN
cord-298458-p7rvupjo	316	6	to	to	IN
cord-298458-p7rvupjo	316	7	influenza	influenza	NN
cord-298458-p7rvupjo	316	8	Recovery	recovery	NN
cord-298458-p7rvupjo	316	9	from	from	IN
cord-298458-p7rvupjo	316	10	severe	severe	JJ
cord-298458-p7rvupjo	316	11	H7N9	H7N9	NNP
cord-298458-p7rvupjo	316	12	disease	disease	NN
cord-298458-p7rvupjo	316	13	is	be	VBZ
cord-298458-p7rvupjo	316	14	associated	associate	VBN
cord-298458-p7rvupjo	316	15	with	with	IN
cord-298458-p7rvupjo	316	16	diverse	diverse	JJ
cord-298458-p7rvupjo	316	17	response	response	NN
cord-298458-p7rvupjo	316	18	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	316	19	dominated	dominate	VBN
cord-298458-p7rvupjo	316	20	by	by	IN
cord-298458-p7rvupjo	316	21	CD8(+	cd8(+	CD
cord-298458-p7rvupjo	316	22	)	)	-RRB-
cord-298458-p7rvupjo	317	1	T	T	NNP
cord-298458-p7rvupjo	317	2	cells	cell	NNS
cord-298458-p7rvupjo	317	3	CD8	CD8	NNP
cord-298458-p7rvupjo	317	4	+	+	CC
cord-298458-p7rvupjo	317	5	T	t	NN
cord-298458-p7rvupjo	317	6	cell	cell	NN
cord-298458-p7rvupjo	317	7	effector	effector	NN
cord-298458-p7rvupjo	317	8	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	317	9	in	in	IN
cord-298458-p7rvupjo	317	10	resistance	resistance	NN
cord-298458-p7rvupjo	317	11	to	to	IN
cord-298458-p7rvupjo	317	12	infection	infection	NN
cord-298458-p7rvupjo	318	1	CD8	CD8	NNP
cord-298458-p7rvupjo	318	2	+	+	CC
cord-298458-p7rvupjo	318	3	T	T	NNP
cord-298458-p7rvupjo	318	4	cells	cell	NNS
cord-298458-p7rvupjo	318	5	clear	clear	JJ
cord-298458-p7rvupjo	318	6	influenza	influenza	NN
cord-298458-p7rvupjo	318	7	virus	virus	NN
cord-298458-p7rvupjo	318	8	by	by	IN
cord-298458-p7rvupjo	318	9	perforin	perforin	NNP
cord-298458-p7rvupjo	318	10	or	or	CC
cord-298458-p7rvupjo	318	11	Fas	Fas	NNP
cord-298458-p7rvupjo	318	12	-	-	HYPH
cord-298458-p7rvupjo	318	13	dependent	dependent	JJ
cord-298458-p7rvupjo	318	14	processes	process	VBZ
cord-298458-p7rvupjo	318	15	Multiple	multiple	JJ
cord-298458-p7rvupjo	318	16	redundant	redundant	JJ
cord-298458-p7rvupjo	318	17	effector	effector	NN
cord-298458-p7rvupjo	318	18	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	318	19	of	of	IN
cord-298458-p7rvupjo	318	20	CD8	CD8	NNP
cord-298458-p7rvupjo	318	21	+	+	CC
cord-298458-p7rvupjo	318	22	T	T	NNP
cord-298458-p7rvupjo	318	23	cells	cell	NNS
cord-298458-p7rvupjo	318	24	protect	protect	VBP
cord-298458-p7rvupjo	318	25	against	against	IN
cord-298458-p7rvupjo	318	26	influenza	influenza	NN
cord-298458-p7rvupjo	318	27	infection	infection	NN
cord-298458-p7rvupjo	318	28	Role	role	NN
cord-298458-p7rvupjo	318	29	of	of	IN
cord-298458-p7rvupjo	318	30	tumor	tumor	NN
cord-298458-p7rvupjo	318	31	necrosis	necrosis	NN
cord-298458-p7rvupjo	318	32	factor	factor	NN
cord-298458-p7rvupjo	318	33	-	-	HYPH
cord-298458-p7rvupjo	318	34	related	relate	VBN
cord-298458-p7rvupjo	318	35	apoptosis	apoptosis	NN
cord-298458-p7rvupjo	318	36	-	-	HYPH
cord-298458-p7rvupjo	318	37	inducing	induce	VBG
cord-298458-p7rvupjo	318	38	ligand	ligand	NN
cord-298458-p7rvupjo	318	39	in	in	IN
cord-298458-p7rvupjo	318	40	immune	immune	JJ
cord-298458-p7rvupjo	318	41	response	response	NN
cord-298458-p7rvupjo	318	42	to	to	IN
cord-298458-p7rvupjo	318	43	influenza	influenza	NN
cord-298458-p7rvupjo	318	44	virus	virus	NN
cord-298458-p7rvupjo	318	45	infection	infection	NN
cord-298458-p7rvupjo	318	46	in	in	IN
cord-298458-p7rvupjo	318	47	mice	mouse	NNS
cord-298458-p7rvupjo	319	1	CD8	CD8	NNP
cord-298458-p7rvupjo	319	2	T	T	NNP
cord-298458-p7rvupjo	319	3	cells	cell	NNS
cord-298458-p7rvupjo	319	4	utilize	utilize	VBP
cord-298458-p7rvupjo	319	5	TRAIL	TRAIL	NNP
cord-298458-p7rvupjo	319	6	to	to	TO
cord-298458-p7rvupjo	319	7	control	control	VB
cord-298458-p7rvupjo	319	8	influenza	influenza	NN
cord-298458-p7rvupjo	319	9	virus	virus	NN
cord-298458-p7rvupjo	319	10	infection	infection	NN
cord-298458-p7rvupjo	319	11	Alternative	alternative	JJ
cord-298458-p7rvupjo	319	12	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	319	13	of	of	IN
cord-298458-p7rvupjo	319	14	respira	respira	NNP
cord-298458-p7rvupjo	319	15	tory	tory	NNP
cord-298458-p7rvupjo	319	16	syncytial	syncytial	JJ
cord-298458-p7rvupjo	319	17	virus	virus	NN
cord-298458-p7rvupjo	319	18	clearance	clearance	NN
cord-298458-p7rvupjo	319	19	in	in	IN
cord-298458-p7rvupjo	319	20	perforin	perforin	NNP
cord-298458-p7rvupjo	319	21	knockout	knockout	NN
cord-298458-p7rvupjo	319	22	mice	mouse	NNS
cord-298458-p7rvupjo	320	1	lead	lead	VB
cord-298458-p7rvupjo	320	2	to	to	IN
cord-298458-p7rvupjo	320	3	enhanced	enhance	VBN
cord-298458-p7rvupjo	320	4	disease	disease	NN
cord-298458-p7rvupjo	320	5	Prolonged	prolong	VBN
cord-298458-p7rvupjo	320	6	production	production	NN
cord-298458-p7rvupjo	320	7	of	of	IN
cord-298458-p7rvupjo	320	8	TNF	tnf	NN
cord-298458-p7rvupjo	320	9	-	-	HYPH
cord-298458-p7rvupjo	320	10	alpha	alpha	NN
cord-298458-p7rvupjo	320	11	exacerbates	exacerbate	VBZ
cord-298458-p7rvupjo	320	12	illness	illness	NN
cord-298458-p7rvupjo	320	13	during	during	IN
cord-298458-p7rvupjo	321	1	respiratory	respiratory	JJ
cord-298458-p7rvupjo	321	2	syncytial	syncytial	JJ
cord-298458-p7rvupjo	321	3	virus	virus	NN
cord-298458-p7rvupjo	321	4	infection	infection	NN
cord-298458-p7rvupjo	321	5	Inhibition	inhibition	NN
cord-298458-p7rvupjo	321	6	of	of	IN
cord-298458-p7rvupjo	321	7	tumor	tumor	NN
cord-298458-p7rvupjo	321	8	necrosis	necrosis	NN
cord-298458-p7rvupjo	321	9	factor	factor	NN
cord-298458-p7rvupjo	321	10	reduces	reduce	VBZ
cord-298458-p7rvupjo	321	11	the	the	DT
cord-298458-p7rvupjo	321	12	severity	severity	NN
cord-298458-p7rvupjo	321	13	of	of	IN
cord-298458-p7rvupjo	321	14	virus	virus	NN
cord-298458-p7rvupjo	321	15	-	-	HYPH
cord-298458-p7rvupjo	321	16	specific	specific	JJ
cord-298458-p7rvupjo	321	17	lung	lung	NN
cord-298458-p7rvupjo	321	18	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	321	19	Role	role	NN
cord-298458-p7rvupjo	321	20	of	of	IN
cord-298458-p7rvupjo	321	21	T	T	NNP
cord-298458-p7rvupjo	321	22	cells	cell	NNS
cord-298458-p7rvupjo	321	23	in	in	IN
cord-298458-p7rvupjo	321	24	virus	virus	NN
cord-298458-p7rvupjo	321	25	control	control	NN
cord-298458-p7rvupjo	321	26	and	and	CC
cord-298458-p7rvupjo	321	27	disease	disease	NN
cord-298458-p7rvupjo	321	28	after	after	IN
cord-298458-p7rvupjo	321	29	infection	infection	NN
cord-298458-p7rvupjo	321	30	with	with	IN
cord-298458-p7rvupjo	321	31	pneumonia	pneumonia	NN
cord-298458-p7rvupjo	321	32	virus	virus	NN
cord-298458-p7rvupjo	321	33	of	of	IN
cord-298458-p7rvupjo	321	34	mice	mouse	NNS
cord-298458-p7rvupjo	321	35	Production	Production	NNP
cord-298458-p7rvupjo	321	36	of	of	IN
cord-298458-p7rvupjo	321	37	interferon	interferon	NN
cord-298458-p7rvupjo	321	38	-	-	HYPH
cord-298458-p7rvupjo	321	39	gamma	gamma	NN
cord-298458-p7rvupjo	321	40	by	by	IN
cord-298458-p7rvupjo	321	41	influenza	influenza	NN
cord-298458-p7rvupjo	321	42	hemagglutinin	hemagglutinin	NN
cord-298458-p7rvupjo	321	43	-	-	HYPH
cord-298458-p7rvupjo	321	44	specific	specific	JJ
cord-298458-p7rvupjo	321	45	CD8	CD8	NNP
cord-298458-p7rvupjo	321	46	effector	effector	VBP
cord-298458-p7rvupjo	321	47	T	T	NNP
cord-298458-p7rvupjo	321	48	cells	cell	NNS
cord-298458-p7rvupjo	321	49	influences	influence	VBZ
cord-298458-p7rvupjo	321	50	the	the	DT
cord-298458-p7rvupjo	321	51	development	development	NN
cord-298458-p7rvupjo	321	52	of	of	IN
cord-298458-p7rvupjo	321	53	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	321	54	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	322	1	The	the	DT
cord-298458-p7rvupjo	322	2	role	role	NN
cord-298458-p7rvupjo	322	3	of	of	IN
cord-298458-p7rvupjo	322	4	IFN	IFN	NNP
cord-298458-p7rvupjo	322	5	in	in	IN
cord-298458-p7rvupjo	322	6	respiratory	respiratory	JJ
cord-298458-p7rvupjo	322	7	syncytial	syncytial	JJ
cord-298458-p7rvupjo	322	8	virus	virus	NN
cord-298458-p7rvupjo	322	9	pathogenesis	pathogenesis	NN
cord-298458-p7rvupjo	322	10	Recombinant	recombinant	JJ
cord-298458-p7rvupjo	322	11	baculovirus	baculovirus	NN
cord-298458-p7rvupjo	322	12	-	-	HYPH
cord-298458-p7rvupjo	322	13	based	base	VBN
cord-298458-p7rvupjo	322	14	vaccine	vaccine	NN
cord-298458-p7rvupjo	322	15	expressing	express	VBG
cord-298458-p7rvupjo	322	16	M2	M2	NNP
cord-298458-p7rvupjo	322	17	protein	protein	NN
cord-298458-p7rvupjo	322	18	induces	induce	VBZ
cord-298458-p7rvupjo	322	19	protective	protective	JJ
cord-298458-p7rvupjo	322	20	CD8	CD8	NNP
cord-298458-p7rvupjo	322	21	+	+	CC
cord-298458-p7rvupjo	322	22	T	t	NN
cord-298458-p7rvupjo	322	23	-	-	HYPH
cord-298458-p7rvupjo	322	24	cell	cell	NN
cord-298458-p7rvupjo	322	25	immunity	immunity	NN
cord-298458-p7rvupjo	322	26	against	against	IN
cord-298458-p7rvupjo	322	27	respiratory	respiratory	JJ
cord-298458-p7rvupjo	322	28	syncytial	syncytial	JJ
cord-298458-p7rvupjo	322	29	virus	virus	NN
cord-298458-p7rvupjo	322	30	infection	infection	NN
cord-298458-p7rvupjo	322	31	Lung	Lung	NNP
cord-298458-p7rvupjo	322	32	CD8	CD8	NNP
cord-298458-p7rvupjo	322	33	+	+	CC
cord-298458-p7rvupjo	322	34	T	t	NN
cord-298458-p7rvupjo	322	35	cell	cell	NN
cord-298458-p7rvupjo	322	36	impairment	impairment	NN
cord-298458-p7rvupjo	322	37	occurs	occur	VBZ
cord-298458-p7rvupjo	322	38	during	during	IN
cord-298458-p7rvupjo	322	39	human	human	JJ
cord-298458-p7rvupjo	322	40	metapneumovirus	metapneumovirus	JJ
cord-298458-p7rvupjo	322	41	infection	infection	NN
cord-298458-p7rvupjo	322	42	despite	despite	IN
cord-298458-p7rvupjo	322	43	virus	virus	NN
cord-298458-p7rvupjo	322	44	-	-	HYPH
cord-298458-p7rvupjo	322	45	like	like	JJ
cord-298458-p7rvupjo	322	46	particle	particle	NN
cord-298458-p7rvupjo	322	47	induction	induction	NN
cord-298458-p7rvupjo	322	48	of	of	IN
cord-298458-p7rvupjo	322	49	functional	functional	JJ
cord-298458-p7rvupjo	322	50	CD8	CD8	NNP
cord-298458-p7rvupjo	322	51	+	+	CC
cord-298458-p7rvupjo	322	52	T	T	NNP
cord-298458-p7rvupjo	322	53	cells	cell	NNS
cord-298458-p7rvupjo	323	1	Cytotoxic	Cytotoxic	NNP
cord-298458-p7rvupjo	323	2	T	t	NN
cord-298458-p7rvupjo	323	3	-	-	HYPH
cord-298458-p7rvupjo	323	4	lymphocyte	lymphocyte	NN
cord-298458-p7rvupjo	323	5	epitope	epitope	NN
cord-298458-p7rvupjo	323	6	vaccination	vaccination	NN
cord-298458-p7rvupjo	323	7	protects	protect	VBZ
cord-298458-p7rvupjo	323	8	against	against	IN
cord-298458-p7rvupjo	323	9	human	human	JJ
cord-298458-p7rvupjo	323	10	metapneumovirus	metapneumovirus	JJ
cord-298458-p7rvupjo	323	11	infection	infection	NN
cord-298458-p7rvupjo	323	12	and	and	CC
cord-298458-p7rvupjo	323	13	disease	disease	NN
cord-298458-p7rvupjo	323	14	in	in	IN
cord-298458-p7rvupjo	323	15	mice	mice	NNP
cord-298458-p7rvupjo	323	16	Vaccine	vaccine	NN
cord-298458-p7rvupjo	323	17	-	-	HYPH
cord-298458-p7rvupjo	323	18	elicited	elicit	VBN
cord-298458-p7rvupjo	323	19	CD8	CD8	NNP
cord-298458-p7rvupjo	323	20	+	+	CC
cord-298458-p7rvupjo	323	21	T	T	NNP
cord-298458-p7rvupjo	323	22	cells	cell	NNS
cord-298458-p7rvupjo	323	23	protect	protect	VBP
cord-298458-p7rvupjo	323	24	against	against	IN
cord-298458-p7rvupjo	323	25	respiratory	respiratory	JJ
cord-298458-p7rvupjo	323	26	syncytial	syncytial	JJ
cord-298458-p7rvupjo	323	27	virus	virus	NN
cord-298458-p7rvupjo	323	28	strain	strain	NN
cord-298458-p7rvupjo	323	29	A2-line19F	a2-line19f	NN
cord-298458-p7rvupjo	323	30	-	-	HYPH
cord-298458-p7rvupjo	323	31	induced	induce	VBN
cord-298458-p7rvupjo	323	32	pathogenesis	pathogenesis	NN
cord-298458-p7rvupjo	323	33	in	in	IN
cord-298458-p7rvupjo	323	34	BALB	BALB	NNP
cord-298458-p7rvupjo	323	35	/	/	SYM
cord-298458-p7rvupjo	323	36	c	c	NN
cord-298458-p7rvupjo	323	37	mice	mouse	NNS
cord-298458-p7rvupjo	323	38	Induction	Induction	NNP
cord-298458-p7rvupjo	323	39	of	of	IN
cord-298458-p7rvupjo	323	40	partial	partial	JJ
cord-298458-p7rvupjo	323	41	specific	specific	JJ
cord-298458-p7rvupjo	323	42	heterotypic	heterotypic	JJ
cord-298458-p7rvupjo	323	43	immunity	immunity	NN
cord-298458-p7rvupjo	323	44	in	in	IN
cord-298458-p7rvupjo	323	45	mice	mouse	NNS
cord-298458-p7rvupjo	323	46	by	by	IN
cord-298458-p7rvupjo	323	47	a	a	DT
cord-298458-p7rvupjo	323	48	single	single	JJ
cord-298458-p7rvupjo	323	49	infection	infection	NN
cord-298458-p7rvupjo	323	50	with	with	IN
cord-298458-p7rvupjo	323	51	influenza	influenza	NN
cord-298458-p7rvupjo	323	52	a	a	DT
cord-298458-p7rvupjo	323	53	virus	virus	NN
cord-298458-p7rvupjo	324	1	Heterosubtypic	heterosubtypic	JJ
cord-298458-p7rvupjo	324	2	immunity	immunity	NN
cord-298458-p7rvupjo	324	3	to	to	IN
cord-298458-p7rvupjo	324	4	influenza	influenza	NN
cord-298458-p7rvupjo	324	5	type	type	VB
cord-298458-p7rvupjo	324	6	A	a	DT
cord-298458-p7rvupjo	324	7	virus	virus	NN
cord-298458-p7rvupjo	324	8	in	in	IN
cord-298458-p7rvupjo	324	9	mice	mouse	NNS
cord-298458-p7rvupjo	324	10	.	.	.
cord-298458-p7rvupjo	325	1	Effector	effector	NN
cord-298458-p7rvupjo	325	2	mechanisms	mechanism	NNS
cord-298458-p7rvupjo	325	3	and	and	CC
cord-298458-p7rvupjo	325	4	their	-PRON-	PRP$
cord-298458-p7rvupjo	325	5	longevity	longevity	NN
cord-298458-p7rvupjo	325	6	Profound	profound	JJ
cord-298458-p7rvupjo	325	7	protection	protection	NN
cord-298458-p7rvupjo	325	8	against	against	IN
cord-298458-p7rvupjo	325	9	respiratory	respiratory	JJ
cord-298458-p7rvupjo	325	10	challenge	challenge	NN
cord-298458-p7rvupjo	325	11	with	with	IN
cord-298458-p7rvupjo	325	12	a	a	DT
cord-298458-p7rvupjo	325	13	lethal	lethal	JJ
cord-298458-p7rvupjo	325	14	H7N7	H7N7	NNP
cord-298458-p7rvupjo	325	15	influenza	influenza	NN
cord-298458-p7rvupjo	325	16	A	a	DT
cord-298458-p7rvupjo	325	17	virus	virus	NN
cord-298458-p7rvupjo	325	18	by	by	IN
cord-298458-p7rvupjo	325	19	increasing	increase	VBG
cord-298458-p7rvupjo	325	20	the	the	DT
cord-298458-p7rvupjo	325	21	magnitude	magnitude	NN
cord-298458-p7rvupjo	325	22	of	of	IN
cord-298458-p7rvupjo	325	23	CD8	CD8	NNP
cord-298458-p7rvupjo	325	24	+	+	CC
cord-298458-p7rvupjo	325	25	T	t	NN
cord-298458-p7rvupjo	325	26	-	-	HYPH
cord-298458-p7rvupjo	325	27	cell	cell	NN
cord-298458-p7rvupjo	325	28	memory	memory	NN
cord-298458-p7rvupjo	325	29	Protective	protective	JJ
cord-298458-p7rvupjo	325	30	cross	cross	JJ
cord-298458-p7rvupjo	325	31	-	-	JJ
cord-298458-p7rvupjo	325	32	reactive	reactive	JJ
cord-298458-p7rvupjo	325	33	cellular	cellular	JJ
cord-298458-p7rvupjo	325	34	immunity	immunity	NN
cord-298458-p7rvupjo	325	35	to	to	TO
cord-298458-p7rvupjo	325	36	lethal	lethal	JJ
cord-298458-p7rvupjo	325	37	A	A	NNP
cord-298458-p7rvupjo	325	38	/	/	SYM
cord-298458-p7rvupjo	325	39	Goose	Goose	NNP
cord-298458-p7rvupjo	325	40	/	/	SYM
cord-298458-p7rvupjo	325	41	Guangdong/1/96-like	guangdong/1/96-like	JJ
cord-298458-p7rvupjo	325	42	H5N1	H5N1	NNP
cord-298458-p7rvupjo	325	43	influenza	influenza	NN
cord-298458-p7rvupjo	325	44	virus	virus	NN
cord-298458-p7rvupjo	325	45	is	be	VBZ
cord-298458-p7rvupjo	325	46	correlated	correlate	VBN
cord-298458-p7rvupjo	325	47	with	with	IN
cord-298458-p7rvupjo	325	48	the	the	DT
cord-298458-p7rvupjo	325	49	proportion	proportion	NN
cord-298458-p7rvupjo	325	50	of	of	IN
cord-298458-p7rvupjo	325	51	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	325	52	CD8	CD8	NNP
cord-298458-p7rvupjo	325	53	+	+	CC
cord-298458-p7rvupjo	325	54	T	T	NNP
cord-298458-p7rvupjo	325	55	cells	cell	NNS
cord-298458-p7rvupjo	325	56	expressing	express	VBG
cord-298458-p7rvupjo	325	57	gamma	gamma	NN
cord-298458-p7rvupjo	325	58	interferon	interferon	NNP
cord-298458-p7rvupjo	325	59	Cross	Cross	NNP
cord-298458-p7rvupjo	325	60	-	-	HYPH
cord-298458-p7rvupjo	325	61	reactive	reactive	JJ
cord-298458-p7rvupjo	325	62	T	t	NN
cord-298458-p7rvupjo	325	63	cells	cell	NNS
cord-298458-p7rvupjo	325	64	are	be	VBP
cord-298458-p7rvupjo	325	65	involved	involve	VBN
cord-298458-p7rvupjo	325	66	in	in	IN
cord-298458-p7rvupjo	325	67	rapid	rapid	JJ
cord-298458-p7rvupjo	325	68	clearance	clearance	NN
cord-298458-p7rvupjo	325	69	of	of	IN
cord-298458-p7rvupjo	325	70	2009	2009	CD
cord-298458-p7rvupjo	325	71	pandemic	pandemic	NN
cord-298458-p7rvupjo	325	72	H1N1	H1N1	NNP
cord-298458-p7rvupjo	325	73	influenza	influenza	NN
cord-298458-p7rvupjo	325	74	virus	virus	NN
cord-298458-p7rvupjo	325	75	in	in	IN
cord-298458-p7rvupjo	325	76	nonhuman	nonhuman	NN
cord-298458-p7rvupjo	325	77	primates	primate	NNS
cord-298458-p7rvupjo	325	78	Natural	natural	JJ
cord-298458-p7rvupjo	325	79	T	T	NNP
cord-298458-p7rvupjo	325	80	cell	cell	NN
cord-298458-p7rvupjo	325	81	-	-	HYPH
cord-298458-p7rvupjo	325	82	mediated	mediate	VBN
cord-298458-p7rvupjo	325	83	protection	protection	NN
cord-298458-p7rvupjo	325	84	against	against	IN
cord-298458-p7rvupjo	325	85	seasonal	seasonal	JJ
cord-298458-p7rvupjo	325	86	and	and	CC
cord-298458-p7rvupjo	325	87	pandemic	pandemic	NN
cord-298458-p7rvupjo	325	88	influenza	influenza	NN
cord-298458-p7rvupjo	325	89	.	.	.
cord-298458-p7rvupjo	326	1	Results	result	NNS
cord-298458-p7rvupjo	326	2	of	of	IN
cord-298458-p7rvupjo	326	3	the	the	DT
cord-298458-p7rvupjo	326	4	flu	flu	NN
cord-298458-p7rvupjo	326	5	watch	watch	NN
cord-298458-p7rvupjo	326	6	cohort	cohort	NN
cord-298458-p7rvupjo	326	7	study	study	NN
cord-298458-p7rvupjo	326	8	Natural	natural	JJ
cord-298458-p7rvupjo	326	9	reinfection	reinfection	NN
cord-298458-p7rvupjo	326	10	with	with	IN
cord-298458-p7rvupjo	326	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	326	12	syncytial	syncytial	JJ
cord-298458-p7rvupjo	326	13	virus	virus	NN
cord-298458-p7rvupjo	326	14	does	do	VBZ
cord-298458-p7rvupjo	326	15	not	not	RB
cord-298458-p7rvupjo	326	16	boost	boost	VB
cord-298458-p7rvupjo	326	17	virus	virus	NN
cord-298458-p7rvupjo	326	18	-	-	HYPH
cord-298458-p7rvupjo	326	19	specific	specific	JJ
cord-298458-p7rvupjo	326	20	T	t	NN
cord-298458-p7rvupjo	326	21	-	-	HYPH
cord-298458-p7rvupjo	326	22	cell	cell	NN
cord-298458-p7rvupjo	326	23	immunity	immunity	NN
cord-298458-p7rvupjo	326	24	Transgenic	transgenic	JJ
cord-298458-p7rvupjo	326	25	mice	mouse	NNS
cord-298458-p7rvupjo	326	26	lacking	lack	VBG
cord-298458-p7rvupjo	326	27	class	class	NN
cord-298458-p7rvupjo	327	1	I	-PRON-	PRP
cord-298458-p7rvupjo	327	2	major	major	JJ
cord-298458-p7rvupjo	327	3	histocompatibility	histocompatibility	NN
cord-298458-p7rvupjo	327	4	complex	complex	NN
cord-298458-p7rvupjo	327	5	-	-	HYPH
cord-298458-p7rvupjo	327	6	restricted	restrict	VBN
cord-298458-p7rvupjo	327	7	T	t	NN
cord-298458-p7rvupjo	327	8	cells	cell	NNS
cord-298458-p7rvupjo	327	9	have	have	VBP
cord-298458-p7rvupjo	327	10	delayed	delay	VBN
cord-298458-p7rvupjo	327	11	viral	viral	JJ
cord-298458-p7rvupjo	327	12	clearance	clearance	NN
cord-298458-p7rvupjo	327	13	and	and	CC
cord-298458-p7rvupjo	327	14	increased	increase	VBN
cord-298458-p7rvupjo	327	15	mortality	mortality	NN
cord-298458-p7rvupjo	327	16	after	after	IN
cord-298458-p7rvupjo	327	17	influenza	influenza	NN
cord-298458-p7rvupjo	327	18	virus	virus	NN
cord-298458-p7rvupjo	327	19	challenge	challenge	NN
cord-298458-p7rvupjo	328	1	The	the	DT
cord-298458-p7rvupjo	328	2	chemokine	chemokine	NN
cord-298458-p7rvupjo	328	3	MIP1alpha	MIP1alpha	NNP
cord-298458-p7rvupjo	328	4	/	/	SYM
cord-298458-p7rvupjo	328	5	CCL3	CCL3	NNP
cord-298458-p7rvupjo	328	6	determines	determine	VBZ
cord-298458-p7rvupjo	328	7	pathology	pathology	NN
cord-298458-p7rvupjo	328	8	in	in	IN
cord-298458-p7rvupjo	328	9	primary	primary	JJ
cord-298458-p7rvupjo	328	10	RSV	RSV	NNP
cord-298458-p7rvupjo	328	11	infection	infection	NN
cord-298458-p7rvupjo	328	12	by	by	IN
cord-298458-p7rvupjo	328	13	regulating	regulate	VBG
cord-298458-p7rvupjo	328	14	the	the	DT
cord-298458-p7rvupjo	328	15	balance	balance	NN
cord-298458-p7rvupjo	328	16	of	of	IN
cord-298458-p7rvupjo	328	17	T	t	NN
cord-298458-p7rvupjo	328	18	cell	cell	NN
cord-298458-p7rvupjo	328	19	populations	population	NNS
cord-298458-p7rvupjo	328	20	in	in	IN
cord-298458-p7rvupjo	328	21	the	the	DT
cord-298458-p7rvupjo	328	22	murine	murine	JJ
cord-298458-p7rvupjo	328	23	lung	lung	NN
cord-298458-p7rvupjo	328	24	Animal	Animal	NNP
cord-298458-p7rvupjo	328	25	model	model	NN
cord-298458-p7rvupjo	328	26	of	of	IN
cord-298458-p7rvupjo	328	27	respiratory	respiratory	JJ
cord-298458-p7rvupjo	328	28	syncytial	syncytial	JJ
cord-298458-p7rvupjo	328	29	virus	virus	NN
cord-298458-p7rvupjo	328	30	:	:	:
cord-298458-p7rvupjo	328	31	CD8	CD8	NNP
cord-298458-p7rvupjo	328	32	+	+	CC
cord-298458-p7rvupjo	328	33	T	T	NNP
cord-298458-p7rvupjo	328	34	cells	cell	NNS
cord-298458-p7rvupjo	328	35	cause	cause	VBP
cord-298458-p7rvupjo	328	36	a	a	DT
cord-298458-p7rvupjo	328	37	cytokine	cytokine	NN
cord-298458-p7rvupjo	328	38	storm	storm	NN
cord-298458-p7rvupjo	328	39	that	that	WDT
cord-298458-p7rvupjo	328	40	is	be	VBZ
cord-298458-p7rvupjo	328	41	chemically	chemically	RB
cord-298458-p7rvupjo	328	42	tractable	tractable	JJ
cord-298458-p7rvupjo	328	43	by	by	IN
cord-298458-p7rvupjo	328	44	sphingosine-1-phosphate	sphingosine-1-phosphate	NNP
cord-298458-p7rvupjo	328	45	1	1	CD
cord-298458-p7rvupjo	328	46	receptor	receptor	NN
cord-298458-p7rvupjo	328	47	agonist	agonist	NN
cord-298458-p7rvupjo	328	48	therapy	therapy	NN
cord-298458-p7rvupjo	328	49	Activation	Activation	NNP
cord-298458-p7rvupjo	328	50	of	of	IN
cord-298458-p7rvupjo	328	51	the	the	DT
cord-298458-p7rvupjo	328	52	granzyme	granzyme	NNP
cord-298458-p7rvupjo	328	53	pathway	pathway	NN
cord-298458-p7rvupjo	328	54	in	in	IN
cord-298458-p7rvupjo	328	55	children	child	NNS
cord-298458-p7rvupjo	328	56	with	with	IN
cord-298458-p7rvupjo	328	57	severe	severe	JJ
cord-298458-p7rvupjo	328	58	respiratory	respiratory	JJ
cord-298458-p7rvupjo	328	59	syncytial	syncytial	JJ
cord-298458-p7rvupjo	328	60	virus	virus	NN
cord-298458-p7rvupjo	328	61	infection	infection	NN
cord-298458-p7rvupjo	328	62	Severe	severe	JJ
cord-298458-p7rvupjo	328	63	human	human	JJ
cord-298458-p7rvupjo	328	64	lower	low	JJR
cord-298458-p7rvupjo	328	65	respiratory	respiratory	JJ
cord-298458-p7rvupjo	328	66	tract	tract	NN
cord-298458-p7rvupjo	328	67	illness	illness	NN
cord-298458-p7rvupjo	328	68	caused	cause	VBN
cord-298458-p7rvupjo	328	69	by	by	IN
cord-298458-p7rvupjo	328	70	respiratory	respiratory	JJ
cord-298458-p7rvupjo	328	71	syncytial	syncytial	JJ
cord-298458-p7rvupjo	328	72	virus	virus	NN
cord-298458-p7rvupjo	328	73	and	and	CC
cord-298458-p7rvupjo	328	74	influenza	influenza	NN
cord-298458-p7rvupjo	328	75	virus	virus	NN
cord-298458-p7rvupjo	328	76	is	be	VBZ
cord-298458-p7rvupjo	328	77	characterized	characterize	VBN
cord-298458-p7rvupjo	328	78	by	by	IN
cord-298458-p7rvupjo	328	79	the	the	DT
cord-298458-p7rvupjo	328	80	absence	absence	NN
cord-298458-p7rvupjo	328	81	of	of	IN
cord-298458-p7rvupjo	328	82	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	328	83	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	328	84	lymphocyte	lymphocyte	NN
cord-298458-p7rvupjo	328	85	responses	response	NNS
cord-298458-p7rvupjo	328	86	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	328	87	syncytial	syncytial	JJ
cord-298458-p7rvupjo	328	88	virus	virus	NN
cord-298458-p7rvupjo	328	89	and	and	CC
cord-298458-p7rvupjo	328	90	influenza	influenza	NN
cord-298458-p7rvupjo	328	91	virus	virus	NN
cord-298458-p7rvupjo	328	92	infections	infection	NNS
cord-298458-p7rvupjo	328	93	:	:	:
cord-298458-p7rvupjo	328	94	observations	observation	NNS
cord-298458-p7rvupjo	328	95	from	from	IN
cord-298458-p7rvupjo	328	96	tissues	tissue	NNS
cord-298458-p7rvupjo	328	97	of	of	IN
cord-298458-p7rvupjo	328	98	fatal	fatal	JJ
cord-298458-p7rvupjo	328	99	infant	infant	NN
cord-298458-p7rvupjo	328	100	cases	case	NNS
cord-298458-p7rvupjo	329	1	Whole	whole	JJ
cord-298458-p7rvupjo	329	2	blood	blood	NN
cord-298458-p7rvupjo	329	3	gene	gene	NN
cord-298458-p7rvupjo	329	4	expression	expression	NN
cord-298458-p7rvupjo	329	5	profiles	profile	NNS
cord-298458-p7rvupjo	329	6	to	to	TO
cord-298458-p7rvupjo	329	7	assess	assess	VB
cord-298458-p7rvupjo	329	8	pathogenesis	pathogenesis	NN
cord-298458-p7rvupjo	329	9	and	and	CC
cord-298458-p7rvupjo	329	10	disease	disease	NN
cord-298458-p7rvupjo	329	11	severity	severity	NN
cord-298458-p7rvupjo	329	12	in	in	IN
cord-298458-p7rvupjo	329	13	infants	infant	NNS
cord-298458-p7rvupjo	329	14	with	with	IN
cord-298458-p7rvupjo	329	15	respiratory	respiratory	JJ
cord-298458-p7rvupjo	329	16	syncytial	syncytial	JJ
cord-298458-p7rvupjo	329	17	virus	virus	NN
cord-298458-p7rvupjo	329	18	infection	infection	NN
cord-298458-p7rvupjo	329	19	Respiratory	respiratory	JJ
cord-298458-p7rvupjo	329	20	syncytial	syncytial	JJ
cord-298458-p7rvupjo	329	21	virus	virus	NN
cord-298458-p7rvupjo	329	22	infection	infection	NN
cord-298458-p7rvupjo	329	23	suppresses	suppress	VBZ
cord-298458-p7rvupjo	329	24	lung	lung	NN
cord-298458-p7rvupjo	329	25	CD8	CD8	NNP
cord-298458-p7rvupjo	329	26	+	+	CC
cord-298458-p7rvupjo	329	27	T	t	NN
cord-298458-p7rvupjo	329	28	-	-	HYPH
cord-298458-p7rvupjo	329	29	cell	cell	NN
cord-298458-p7rvupjo	329	30	effector	effector	NN
cord-298458-p7rvupjo	329	31	activity	activity	NN
cord-298458-p7rvupjo	329	32	and	and	CC
cord-298458-p7rvupjo	329	33	peripheral	peripheral	JJ
cord-298458-p7rvupjo	329	34	CD8	CD8	NNP
cord-298458-p7rvupjo	329	35	+	+	CC
cord-298458-p7rvupjo	329	36	T	t	NN
cord-298458-p7rvupjo	329	37	-	-	HYPH
cord-298458-p7rvupjo	329	38	cell	cell	NN
cord-298458-p7rvupjo	329	39	memory	memory	NN
cord-298458-p7rvupjo	329	40	in	in	IN
cord-298458-p7rvupjo	329	41	the	the	DT
cord-298458-p7rvupjo	329	42	respiratory	respiratory	JJ
cord-298458-p7rvupjo	329	43	tract	tract	NN
cord-298458-p7rvupjo	329	44	Functional	functional	JJ
cord-298458-p7rvupjo	329	45	impairment	impairment	NN
cord-298458-p7rvupjo	329	46	of	of	IN
cord-298458-p7rvupjo	329	47	cytotoxic	cytotoxic	JJ
cord-298458-p7rvupjo	329	48	T	t	NN
cord-298458-p7rvupjo	329	49	cells	cell	NNS
cord-298458-p7rvupjo	329	50	in	in	IN
cord-298458-p7rvupjo	329	51	the	the	DT
cord-298458-p7rvupjo	329	52	lung	lung	NN
cord-298458-p7rvupjo	329	53	airways	airway	NNS
cord-298458-p7rvupjo	329	54	following	follow	VBG
cord-298458-p7rvupjo	329	55	respiratory	respiratory	JJ
cord-298458-p7rvupjo	329	56	virus	virus	NN
cord-298458-p7rvupjo	329	57	infections	infection	NNS
cord-298458-p7rvupjo	329	58	Impairment	impairment	JJ
cord-298458-p7rvupjo	329	59	of	of	IN
cord-298458-p7rvupjo	329	60	the	the	DT
cord-298458-p7rvupjo	329	61	CD8	CD8	NNP
cord-298458-p7rvupjo	329	62	+	+	CC
cord-298458-p7rvupjo	329	63	T	T	NNP
cord-298458-p7rvupjo	329	64	cell	cell	NN
cord-298458-p7rvupjo	329	65	response	response	NN
cord-298458-p7rvupjo	329	66	in	in	IN
cord-298458-p7rvupjo	329	67	lungs	lung	NNS
cord-298458-p7rvupjo	329	68	following	follow	VBG
cord-298458-p7rvupjo	329	69	infection	infection	NN
cord-298458-p7rvupjo	329	70	with	with	IN
cord-298458-p7rvupjo	329	71	human	human	JJ
cord-298458-p7rvupjo	329	72	respiratory	respiratory	JJ
cord-298458-p7rvupjo	329	73	syncytial	syncytial	JJ
cord-298458-p7rvupjo	329	74	virus	virus	NN
cord-298458-p7rvupjo	329	75	is	be	VBZ
cord-298458-p7rvupjo	329	76	specific	specific	JJ
cord-298458-p7rvupjo	329	77	to	to	IN
cord-298458-p7rvupjo	329	78	the	the	DT
cord-298458-p7rvupjo	329	79	anatomical	anatomical	JJ
cord-298458-p7rvupjo	329	80	site	site	NN
cord-298458-p7rvupjo	329	81	rather	rather	RB
cord-298458-p7rvupjo	329	82	than	than	IN
cord-298458-p7rvupjo	329	83	the	the	DT
cord-298458-p7rvupjo	329	84	virus	virus	NN
cord-298458-p7rvupjo	329	85	,	,	,
cord-298458-p7rvupjo	329	86	antigen	antigen	NN
cord-298458-p7rvupjo	329	87	,	,	,
cord-298458-p7rvupjo	329	88	or	or	CC
cord-298458-p7rvupjo	329	89	route	route	NN
cord-298458-p7rvupjo	329	90	of	of	IN
cord-298458-p7rvupjo	329	91	infection	infection	NN
cord-298458-p7rvupjo	329	92	Regulation	regulation	NN
cord-298458-p7rvupjo	329	93	of	of	IN
cord-298458-p7rvupjo	329	94	cytokine	cytokine	NN
cord-298458-p7rvupjo	329	95	production	production	NN
cord-298458-p7rvupjo	329	96	by	by	IN
cord-298458-p7rvupjo	329	97	virus	virus	NN
cord-298458-p7rvupjo	329	98	-	-	HYPH
cord-298458-p7rvupjo	329	99	specific	specific	JJ
cord-298458-p7rvupjo	329	100	CD8	CD8	NNP
cord-298458-p7rvupjo	329	101	T	T	NNP
cord-298458-p7rvupjo	329	102	cells	cell	NNS
cord-298458-p7rvupjo	329	103	in	in	IN
cord-298458-p7rvupjo	329	104	the	the	DT
cord-298458-p7rvupjo	329	105	lungs	lung	NNS
cord-298458-p7rvupjo	330	1	Foxp3	foxp3	JJ
cord-298458-p7rvupjo	331	1	+	+	CC
cord-298458-p7rvupjo	331	2	CD4	CD4	NNP
cord-298458-p7rvupjo	331	3	regulatory	regulatory	JJ
cord-298458-p7rvupjo	331	4	T	T	NNP
cord-298458-p7rvupjo	331	5	cells	cell	NNS
cord-298458-p7rvupjo	331	6	limit	limit	VBP
cord-298458-p7rvupjo	331	7	pulmonary	pulmonary	JJ
cord-298458-p7rvupjo	331	8	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	331	9	by	by	IN
cord-298458-p7rvupjo	331	10	modulating	modulate	VBG
cord-298458-p7rvupjo	331	11	the	the	DT
cord-298458-p7rvupjo	331	12	CD8	CD8	NNP
cord-298458-p7rvupjo	331	13	T	T	NNP
cord-298458-p7rvupjo	331	14	cell	cell	NN
cord-298458-p7rvupjo	331	15	response	response	NN
cord-298458-p7rvupjo	331	16	during	during	IN
cord-298458-p7rvupjo	331	17	respiratory	respiratory	JJ
cord-298458-p7rvupjo	331	18	syncytial	syncytial	JJ
cord-298458-p7rvupjo	331	19	virus	virus	NN
cord-298458-p7rvupjo	331	20	infection	infection	NN
cord-298458-p7rvupjo	331	21	Influenza	Influenza	NNP
cord-298458-p7rvupjo	331	22	A	a	DT
cord-298458-p7rvupjo	331	23	virus	virus	NN
cord-298458-p7rvupjo	331	24	infection	infection	NN
cord-298458-p7rvupjo	331	25	results	result	VBZ
cord-298458-p7rvupjo	331	26	in	in	IN
cord-298458-p7rvupjo	331	27	a	a	DT
cord-298458-p7rvupjo	331	28	robust	robust	JJ
cord-298458-p7rvupjo	331	29	,	,	,
cord-298458-p7rvupjo	331	30	antigen	antigen	NN
cord-298458-p7rvupjo	331	31	-	-	HYPH
cord-298458-p7rvupjo	331	32	responsive	responsive	JJ
cord-298458-p7rvupjo	331	33	,	,	,
cord-298458-p7rvupjo	331	34	and	and	CC
cord-298458-p7rvupjo	331	35	widely	widely	RB
cord-298458-p7rvupjo	331	36	disseminated	disseminate	VBN
cord-298458-p7rvupjo	331	37	Foxp3	Foxp3	NNP
cord-298458-p7rvupjo	331	38	+	+	CC
cord-298458-p7rvupjo	332	1	regulatory	regulatory	JJ
cord-298458-p7rvupjo	332	2	T	T	NNP
cord-298458-p7rvupjo	332	3	cell	cell	NN
cord-298458-p7rvupjo	332	4	response	response	NN
cord-298458-p7rvupjo	332	5	Antigen	antigen	NN
cord-298458-p7rvupjo	332	6	-	-	HYPH
cord-298458-p7rvupjo	332	7	specific	specific	JJ
cord-298458-p7rvupjo	332	8	memory	memory	NN
cord-298458-p7rvupjo	332	9	regulatory	regulatory	JJ
cord-298458-p7rvupjo	332	10	CD4+Foxp3	CD4+Foxp3	NNP
cord-298458-p7rvupjo	332	11	+	+	CC
cord-298458-p7rvupjo	332	12	T	T	NNP
cord-298458-p7rvupjo	332	13	cells	cell	NNS
cord-298458-p7rvupjo	332	14	control	control	VBP
cord-298458-p7rvupjo	332	15	memory	memory	NN
cord-298458-p7rvupjo	332	16	responses	response	NNS
cord-298458-p7rvupjo	332	17	to	to	IN
cord-298458-p7rvupjo	332	18	influenza	influenza	NN
cord-298458-p7rvupjo	332	19	virus	virus	NN
cord-298458-p7rvupjo	332	20	infection	infection	NN
cord-298458-p7rvupjo	332	21	Epitope	epitope	NN
cord-298458-p7rvupjo	332	22	-	-	HYPH
cord-298458-p7rvupjo	332	23	specific	specific	JJ
cord-298458-p7rvupjo	332	24	regulatory	regulatory	JJ
cord-298458-p7rvupjo	332	25	CD4	CD4	NNP
cord-298458-p7rvupjo	332	26	T	T	NNP
cord-298458-p7rvupjo	332	27	cells	cell	NNS
cord-298458-p7rvupjo	332	28	reduce	reduce	VBP
cord-298458-p7rvupjo	332	29	virus	virus	NN
cord-298458-p7rvupjo	332	30	-	-	HYPH
cord-298458-p7rvupjo	332	31	induced	induce	VBN
cord-298458-p7rvupjo	332	32	illness	illness	NN
cord-298458-p7rvupjo	332	33	while	while	IN
cord-298458-p7rvupjo	332	34	preserving	preserve	VBG
cord-298458-p7rvupjo	332	35	CD8	CD8	NNP
cord-298458-p7rvupjo	332	36	T	T	NNP
cord-298458-p7rvupjo	332	37	-	-	HYPH
cord-298458-p7rvupjo	332	38	cell	cell	NN
cord-298458-p7rvupjo	332	39	effector	effector	NN
cord-298458-p7rvupjo	332	40	function	function	NN
cord-298458-p7rvupjo	332	41	at	at	IN
cord-298458-p7rvupjo	332	42	the	the	DT
cord-298458-p7rvupjo	332	43	site	site	NN
cord-298458-p7rvupjo	332	44	of	of	IN
cord-298458-p7rvupjo	332	45	infection	infection	NN
cord-298458-p7rvupjo	332	46	Effector	Effector	NNP
cord-298458-p7rvupjo	332	47	T	T	NNP
cord-298458-p7rvupjo	332	48	cells	cell	NNS
cord-298458-p7rvupjo	332	49	control	control	VBP
cord-298458-p7rvupjo	332	50	lung	lung	NN
cord-298458-p7rvupjo	332	51	inflammation	inflammation	NN
cord-298458-p7rvupjo	332	52	during	during	IN
cord-298458-p7rvupjo	332	53	acute	acute	JJ
cord-298458-p7rvupjo	332	54	influenza	influenza	NN
cord-298458-p7rvupjo	332	55	virus	virus	NN
cord-298458-p7rvupjo	332	56	infection	infection	NN
cord-298458-p7rvupjo	332	57	by	by	IN
cord-298458-p7rvupjo	332	58	producing	produce	VBG
cord-298458-p7rvupjo	333	1	IL-10	IL-10	NNP
cord-298458-p7rvupjo	333	2	Multiple	Multiple	NNP
cord-298458-p7rvupjo	333	3	CD4	CD4	NNP
cord-298458-p7rvupjo	333	4	+	+	CC
cord-298458-p7rvupjo	333	5	T	t	NN
cord-298458-p7rvupjo	333	6	cell	cell	NN
cord-298458-p7rvupjo	333	7	subsets	subset	NNS
cord-298458-p7rvupjo	333	8	produce	produce	VBP
cord-298458-p7rvupjo	333	9	immunomodulatory	immunomodulatory	JJ
cord-298458-p7rvupjo	333	10	IL-10	IL-10	NNP
cord-298458-p7rvupjo	333	11	during	during	IN
cord-298458-p7rvupjo	333	12	respiratory	respiratory	JJ
cord-298458-p7rvupjo	333	13	syncytial	syncytial	JJ
cord-298458-p7rvupjo	333	14	virus	virus	NN
cord-298458-p7rvupjo	333	15	infection	infection	NN
cord-298458-p7rvupjo	333	16	IL-10	IL-10	NNP
cord-298458-p7rvupjo	333	17	regulates	regulate	VBZ
cord-298458-p7rvupjo	333	18	viral	viral	JJ
cord-298458-p7rvupjo	333	19	lung	lung	NN
cord-298458-p7rvupjo	333	20	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	333	21	during	during	IN
cord-298458-p7rvupjo	333	22	acute	acute	JJ
cord-298458-p7rvupjo	333	23	respiratory	respiratory	JJ
cord-298458-p7rvupjo	333	24	syncytial	syncytial	JJ
cord-298458-p7rvupjo	333	25	virus	virus	NN
cord-298458-p7rvupjo	333	26	infection	infection	NN
cord-298458-p7rvupjo	333	27	in	in	IN
cord-298458-p7rvupjo	333	28	mice	mouse	NNS
cord-298458-p7rvupjo	334	1	CD8	CD8	NNP
cord-298458-p7rvupjo	334	2	+	+	CC
cord-298458-p7rvupjo	334	3	Treg	Treg	NNP
cord-298458-p7rvupjo	334	4	cells	cell	NNS
cord-298458-p7rvupjo	334	5	suppress	suppress	VBP
cord-298458-p7rvupjo	334	6	CD8	CD8	NNP
cord-298458-p7rvupjo	334	7	+	+	CC
cord-298458-p7rvupjo	334	8	T	T	NNP
cord-298458-p7rvupjo	334	9	cell	cell	NN
cord-298458-p7rvupjo	334	10	-	-	HYPH
cord-298458-p7rvupjo	334	11	responses	response	NNS
cord-298458-p7rvupjo	334	12	by	by	IN
cord-298458-p7rvupjo	334	13	IL-10-dependent	IL-10-dependent	NNP
cord-298458-p7rvupjo	334	14	mechanism	mechanism	NN
cord-298458-p7rvupjo	334	15	during	during	IN
cord-298458-p7rvupjo	334	16	H5N1	H5N1	NNP
cord-298458-p7rvupjo	334	17	influenza	influenza	NN
cord-298458-p7rvupjo	334	18	virus	virus	NN
cord-298458-p7rvupjo	334	19	infection	infection	NN
cord-298458-p7rvupjo	334	20	Local	local	JJ
cord-298458-p7rvupjo	334	21	blockade	blockade	NN
cord-298458-p7rvupjo	334	22	of	of	IN
cord-298458-p7rvupjo	334	23	epithelial	epithelial	JJ
cord-298458-p7rvupjo	334	24	PDL-1	PDL-1	NNP
cord-298458-p7rvupjo	334	25	in	in	IN
cord-298458-p7rvupjo	334	26	the	the	DT
cord-298458-p7rvupjo	334	27	airways	airways	NNP
cord-298458-p7rvupjo	334	28	enhances	enhance	VBZ
cord-298458-p7rvupjo	334	29	T	T	NNP
cord-298458-p7rvupjo	334	30	cell	cell	NN
cord-298458-p7rvupjo	334	31	function	function	NN
cord-298458-p7rvupjo	334	32	and	and	CC
cord-298458-p7rvupjo	334	33	viral	viral	JJ
cord-298458-p7rvupjo	334	34	clearance	clearance	NN
cord-298458-p7rvupjo	334	35	during	during	IN
cord-298458-p7rvupjo	334	36	influenza	influenza	NN
cord-298458-p7rvupjo	334	37	virus	virus	NN
cord-298458-p7rvupjo	334	38	infection	infection	NN
cord-298458-p7rvupjo	334	39	Control	Control	NNP
cord-298458-p7rvupjo	334	40	of	of	IN
cord-298458-p7rvupjo	334	41	pathogenic	pathogenic	JJ
cord-298458-p7rvupjo	334	42	effector	effector	NN
cord-298458-p7rvupjo	334	43	T	t	NN
cord-298458-p7rvupjo	334	44	-	-	HYPH
cord-298458-p7rvupjo	334	45	cell	cell	NN
cord-298458-p7rvupjo	334	46	activities	activity	NNS
cord-298458-p7rvupjo	334	47	in	in	IN
cord-298458-p7rvupjo	334	48	situ	situ	NN
cord-298458-p7rvupjo	334	49	by	by	IN
cord-298458-p7rvupjo	334	50	PD	PD	NNP
cord-298458-p7rvupjo	334	51	-	-	HYPH
cord-298458-p7rvupjo	334	52	L1	L1	NNP
cord-298458-p7rvupjo	334	53	expression	expression	NN
cord-298458-p7rvupjo	334	54	on	on	IN
cord-298458-p7rvupjo	334	55	respiratory	respiratory	JJ
cord-298458-p7rvupjo	334	56	inflammatory	inflammatory	JJ
cord-298458-p7rvupjo	334	57	dendritic	dendritic	JJ
cord-298458-p7rvupjo	334	58	cells	cell	NNS
cord-298458-p7rvupjo	334	59	during	during	IN
cord-298458-p7rvupjo	334	60	respiratory	respiratory	JJ
cord-298458-p7rvupjo	334	61	syncytial	syncytial	JJ
cord-298458-p7rvupjo	334	62	virus	virus	NN
cord-298458-p7rvupjo	334	63	infection	infection	NN
cord-298458-p7rvupjo	334	64	Programmed	program	VBN
cord-298458-p7rvupjo	335	1	death-1	death-1	NNP
cord-298458-p7rvupjo	335	2	impairs	impair	VBZ
cord-298458-p7rvupjo	335	3	secondary	secondary	JJ
cord-298458-p7rvupjo	335	4	effector	effector	NN
cord-298458-p7rvupjo	335	5	lung	lung	NN
cord-298458-p7rvupjo	335	6	CD8	CD8	NNP
cord-298458-p7rvupjo	335	7	+	+	CC
cord-298458-p7rvupjo	335	8	T	T	NNP
cord-298458-p7rvupjo	335	9	cells	cell	NNS
cord-298458-p7rvupjo	335	10	during	during	IN
cord-298458-p7rvupjo	335	11	respiratory	respiratory	JJ
cord-298458-p7rvupjo	335	12	virus	virus	NN
cord-298458-p7rvupjo	335	13	reinfection	reinfection	NN
cord-298458-p7rvupjo	335	14	RSV	RSV	NNP
cord-298458-p7rvupjo	335	15	-	-	HYPH
cord-298458-p7rvupjo	335	16	induced	induce	VBN
cord-298458-p7rvupjo	335	17	bronchial	bronchial	JJ
cord-298458-p7rvupjo	335	18	epithelial	epithelial	JJ
cord-298458-p7rvupjo	335	19	cell	cell	NN
cord-298458-p7rvupjo	335	20	PD	PD	NNP
cord-298458-p7rvupjo	335	21	-	-	HYPH
cord-298458-p7rvupjo	335	22	L1	L1	NNP
cord-298458-p7rvupjo	335	23	expression	expression	NN
cord-298458-p7rvupjo	335	24	inhibits	inhibit	VBZ
cord-298458-p7rvupjo	335	25	CD8	CD8	NNP
cord-298458-p7rvupjo	335	26	+	+	CC
cord-298458-p7rvupjo	335	27	T	T	NNP
cord-298458-p7rvupjo	335	28	cell	cell	NN
cord-298458-p7rvupjo	335	29	nonspecific	nonspecific	JJ
cord-298458-p7rvupjo	335	30	antiviral	antiviral	JJ
cord-298458-p7rvupjo	335	31	activity	activity	NN
cord-298458-p7rvupjo	335	32	Multiple	multiple	JJ
cord-298458-p7rvupjo	335	33	inhibitory	inhibitory	JJ
cord-298458-p7rvupjo	335	34	pathways	pathway	NNS
cord-298458-p7rvupjo	335	35	contribute	contribute	VBP
cord-298458-p7rvupjo	335	36	to	to	IN
cord-298458-p7rvupjo	335	37	lung	lung	NN
cord-298458-p7rvupjo	335	38	CD8	CD8	NNP
cord-298458-p7rvupjo	335	39	+	+	CC
cord-298458-p7rvupjo	335	40	T	T	NNP
cord-298458-p7rvupjo	335	41	cell	cell	NN
cord-298458-p7rvupjo	335	42	impairment	impairment	NN
cord-298458-p7rvupjo	335	43	and	and	CC
cord-298458-p7rvupjo	335	44	protect	protect	VB
cord-298458-p7rvupjo	335	45	against	against	IN
cord-298458-p7rvupjo	335	46	immunopathology	immunopathology	NN
cord-298458-p7rvupjo	335	47	during	during	IN
cord-298458-p7rvupjo	335	48	acute	acute	JJ
cord-298458-p7rvupjo	335	49	viral	viral	JJ
cord-298458-p7rvupjo	335	50	respiratory	respiratory	JJ
cord-298458-p7rvupjo	335	51	infection	infection	NN
cord-298458-p7rvupjo	335	52	T	t	NN
cord-298458-p7rvupjo	335	53	cell	cell	NN
cord-298458-p7rvupjo	335	54	immunoglobulin	immunoglobulin	NN
cord-298458-p7rvupjo	335	55	and	and	CC
cord-298458-p7rvupjo	335	56	mucin	mucin	NN
cord-298458-p7rvupjo	335	57	protein-3	protein-3	NN
cord-298458-p7rvupjo	336	1	(	(	-LRB-
cord-298458-p7rvupjo	336	2	tim-3)/	tim-3)/	``
cord-298458-p7rvupjo	336	3	galectin-9	galectin-9	NNP
cord-298458-p7rvupjo	336	4	interaction	interaction	NN
cord-298458-p7rvupjo	336	5	regulates	regulate	VBZ
cord-298458-p7rvupjo	336	6	influenza	influenza	NN
cord-298458-p7rvupjo	336	7	A	a	DT
cord-298458-p7rvupjo	336	8	virus	virus	NN
cord-298458-p7rvupjo	336	9	-	-	HYPH
cord-298458-p7rvupjo	336	10	specific	specific	JJ
cord-298458-p7rvupjo	336	11	humoral	humoral	JJ
cord-298458-p7rvupjo	336	12	and	and	CC
cord-298458-p7rvupjo	336	13	CD8	CD8	NNP
cord-298458-p7rvupjo	336	14	T	T	NNP
cord-298458-p7rvupjo	336	15	-	-	HYPH
cord-298458-p7rvupjo	336	16	cell	cell	NN
cord-298458-p7rvupjo	336	17	responses	response	NNS