Summary of your 'study carrel' ============================== This is a summary of your Distant Reader 'study carrel'. The Distant Reader harvested & cached your content into a collection/corpus. It then applied sets of natural language processing and text mining against the collection. The results of this process was reduced to a database file -- a 'study carrel'. The study carrel can then be queried, thus bringing light specific characteristics for your collection. These characteristics can help you summarize the collection as well as enumerate things you might want to investigate more closely. This report is a terse narrative report, and when processing is complete you will be linked to a more complete narrative report. Eric Lease Morgan Number of items in the collection; 'How big is my corpus?' ---------------------------------------------------------- 13 Average length of all items measured in words; "More or less, how big is each item?" ------------------------------------------------------------------------------------ 3899 Average readability score of all items (0 = difficult; 100 = easy) ------------------------------------------------------------------ 47 Top 50 statistically significant keywords; "What is my collection about?" ------------------------------------------------------------------------- 5 China 3 SARS 3 MERS 3 COVID-19 2 patient 2 Wuhan 2 Middle 2 East 1 tissue 1 respiratory 1 metabolic 1 growth 1 factor 1 covid-19 1 case 1 authentic 1 Zhejiang 1 Wenzhou 1 Saudi 1 PPE 1 Lonicerae 1 Japonicae 1 January 1 HCP 1 H7N9 1 Flos 1 Fibroblast 1 FGF21 1 FGF19 1 Arabia Top 50 lemmatized nouns; "What is discussed?" --------------------------------------------- 383 case 377 patient 313 coronavirus 225 infection 207 % 183 syndrome 179 study 155 virus 150 disease 146 cell 128 outbreak 106 pneumonia 104 day 103 factor 102 treatment 93 transmission 88 acid 83 growth 75 tissue 72 mouse 70 effect 69 symptom 68 protein 67 receptor 66 level 65 cov 63 health 63 axis 62 contact 61 influenza 59 hospital 58 antibody 56 control 56 child 54 quality 53 time 50 liver 48 family 47 response 45 human 45 geo 45 diagnosis 43 number 42 rate 42 fibroblast 42 epidemic 41 risk 41 result 41 lung 41 death Top 50 proper nouns; "What are the names of persons or places?" -------------------------------------------------------------- 286 MERS 211 CoV 152 COVID-19 151 East 148 Middle 147 China 123 SARS 111 Flos 109 Lonicerae 81 FGF21 76 Japonicae 68 CoV-2 67 Wuhan 56 H7N9 48 Saudi 47 Arabia 43 January 43 FGF 42 Health 38 Fig 37 Coronavirus 35 Province 34 February 33 March 30 mitogenic 30 FGF19 29 RNA 29 HCP 28 Korea 26 al 26 PCR 26 Lonicera 26 Fibroblast 25 Chinese 23 Zhejiang 23 Li 23 Hubei 23 CT 22 et 22 Hospital 21 S 21 . 20 Table 19 WHO 18 Team 18 May 17 World 17 Wenzhou 17 South 17 Organization Top 50 personal pronouns nouns; "To whom are things referred?" ------------------------------------------------------------- 92 we 60 it 35 they 29 he 12 she 10 them 8 i 5 us 3 one 2 you 1 himself Top 50 lemmatized verbs; "What do things do?" --------------------------------------------- 1295 be 272 have 128 confirm 116 show 97 include 96 use 84 increase 80 report 64 cause 63 associate 57 suspect 53 induce 51 infect 46 develop 44 reduce 43 identify 41 indicate 40 treat 40 improve 40 do 38 find 35 require 35 bind 34 test 34 take 34 suggest 33 promote 33 base 32 present 30 detect 29 control 28 prevent 28 observe 28 emerge 28 consider 26 involve 26 inhibit 25 receive 25 follow 25 admit 24 occur 24 lead 23 relate 23 analyze 22 regulate 22 need 22 make 21 result 21 neutralize 20 see Top 50 lemmatized adjectives and adverbs; "How are things described?" --------------------------------------------------------------------- 269 respiratory 125 clinical 109 novel 106 metabolic 101 severe 98 other 97 not 97 also 94 human 94 high 91 - 71 acute 66 first 63 authentic 60 such 58 positive 55 specific 54 viral 53 more 52 different 51 early 49 low 49 covid-19 49 chinese 45 non 43 only 42 new 41 well 41 however 41 critical 37 multiple 37 most 37 avian 33 medical 33 inflammatory 32 public 32 further 30 thus 30 mild 30 important 30 anti 29 as 27 renal 27 ill 26 negative 26 large 26 antiviral 26 active 25 probable 25 highly Top 50 lemmatized superlative adjectives; "How are things described to the extreme?" ------------------------------------------------------------------------- 13 most 8 Most 7 late 7 high 6 large 5 least 3 good 1 common 1 close 1 bad Top 50 lemmatized superlative adverbs; "How do things do to the extreme?" ------------------------------------------------------------------------ 24 most 7 least 2 worst 1 latest 1 hard Top 50 Internet domains; "What Webbed places are alluded to in this corpus?" ---------------------------------------------------------------------------- 1 www.ncbi.nlm.nih 1 www.cas.cn 1 platform.gisaid.org 1 doi.org 1 creativecommons.org Top 50 URLs; "What is hyperlinked from this corpus?" ---------------------------------------------------- 1 http://www.ncbi.nlm.nih 1 http://www.cas.cn/yw/202001/ 1 http://platform.gisaid.org/epi3/ 1 http://doi.org/ 1 http://creativecommons.org/ Top 50 email addresses; "Who are you gonna call?" ------------------------------------------------- Top 50 positive assertions; "What sentences are in the shape of noun-verb-noun?" ------------------------------------------------------------------------------- 4 coronavirus indicating person 3 acid test results 3 cases were secondary 2 cases had coinfection 2 flos is also 2 flos is widely 2 patient had chronic 2 patients presented coagulation 2 studies did not 1 % had bilateral 1 % had severe 1 % presented interlobular 1 % were health 1 % were men 1 % were primary 1 acid are potent 1 acid test kit 1 case had intussusceptions 1 case includes parents 1 case report text 1 case tested positive 1 cases are also 1 cases are less 1 cases are not 1 cases developed critical 1 cases developed severe 1 cases did not 1 cases had histories 1 cases have also 1 cases include advanced 1 cases included several 1 cases increased rapidly 1 cases indicating early 1 cases is not 1 cases presented fever 1 cases showed leucopenia 1 cases was significantly 1 cases were directly 1 cases were similar 1 cases were soon 1 cases were tertiary 1 cells is several 1 cells showed extensive 1 china are all 1 china are geoauthentic 1 china is actually 1 china is ready 1 china was significantly 1 coronavirus causing pneumonia 1 coronavirus causing severe Top 50 negative assertions; "What sentences are in the shape of noun-verb-no|not-noun?" --------------------------------------------------------------------------------------- 1 cases is not unique 1 cov does not yet 1 cov has not yet 1 disease was not likely 1 fgf21 is not only 1 patient had no travel 1 patients did not always 1 patients showed no response 1 studies did not clearly 1 transmission have not yet A rudimentary bibliography -------------------------- id = cord-307995-8q7efrqk author = Al-Tawfiq, Jaffar A. title = Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns date = 2016-05-04 keywords = East; MERS; Middle summary = Middle East respiratory syndrome coronavirus (MERS-CoV): summary and risk assessment of current situation in the Republic of Korea and China -as of 19 Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study A family cluster of Middle East Respiratory syndrome coronavirus infections related to a likely unrecognized asymptomatic or mild case Community case clusters of Middle East respiratory syndrome coronavirus in Hafr Al-Batin, Kingdom of Saudi Arabia: a descriptive genomic study Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study KSA MERS-CoV Investigation Team.Hospital outbreak of Middle East respiratory syndrome coronavirus Middle East respiratory syndrome coronavirus: a case-control study of hospitalized patients Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study doi = 10.1007/s11684-016-0446-y id = cord-330198-pwkxgbxk author = Cai, Xiaofang title = Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19 date = 2020-10-27 keywords = SARS; case; covid-19 summary = All febrile or suspected COVID-19 cases were referred to the fever clinic, and the others-including critically ill children-were received by the emergency department after pediatric 5-level triage. We retrospectively analyzed the clinical data of these children admitted from the emergency department to characterize thoroughly the features of COVID-19 that can be evaluated to distinguish this novel disease from pneumonia caused by other pathogens in pediatric patients. Owing to the parents'' fear that their children were infected with SARS-CoV-2, the median time from symptom onset to hospital admission was shorter for confirmed COVID-19 cases (2.0 days) than that for suspected COVID-19 cases (3.0 days) and non-COVID-19 cases (4.0 days) (P < 0.05). Moreover, serologic testing can serve as an important adjunctive method for COVID-19 diagnosis, especially when the patient is highly suspected of SARS-CoV-2 infection but is found to be negative by nucleic acid testing. doi = 10.1007/s11684-020-0820-7 id = cord-338258-bdyalfcd author = Chen, Enfu title = The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report date = 2013-06-10 keywords = China; H7N9; Zhejiang summary = title: The first avian influenza A (H7N9) viral infection in humans in Zhejiang Province, China: a death report This study reports the first death caused by a novel avian influenza A (H7N9) virus in Zhejiang Province, China. This report is important for assessing and controlling similar cases, and would provide meaningful insights into the early and rapid diagnosis, treatment, prevention, and control of human influenza A (H7N9) viral infections. According to the updated data from 131 cases and 32 deaths, the novel influenza A (H7N9) virus circulating in the urban and rural areas of Beijing and Shanghai, as well as Anhui, Jiangsu, Zhejiang, etc., differs from the avian H5N1 reported in rural areas [15] . About 65% of the confirmed cases had histories of avian exposure, which indicates that contact with live poultry and excreta is a high-risk factor, similar to the H5N1 virus infection in China [17, 18] . doi = 10.1007/s11684-013-0275-1 id = cord-312361-ermbijfq author = Gong, Fanghua title = China’s local governments are combating COVID-19 with unprecedented responses — from a Wenzhou governance perspective date = 2020-03-12 keywords = China; Wenzhou summary = The COVID-19 caused by a novel strain of Coronavirus has been spreading rapidly since its onset in Wuhan, the capital city of central China''s Hubei Province, in December 2019. A novel strain of coronavirus has caused a pneumonia outbreak in the central Chinese city of Wuhan since December 2019 and has been quickly spreading to other parts of China. The two makeshift hospitals are playing major roles in improving the cure rate and decreasing the death rate of infected patients and help China and the world win the combat of prevention against and control of this growing epidemic situation. Similar mass mobilization and harsh measures are under way in severely affected areas in China to ensure the health and safety of people, both Chinese and internationals, and the effective prevention and control of this epidemic for the shared well-being of mankind. doi = 10.1007/s11684-020-0755-z id = cord-006788-kz8i4a6h author = Li, Xiaokun title = The FGF metabolic axis date = 2019-09-07 keywords = FGF19; FGF21; Fibroblast; factor; growth; metabolic; tissue summary = In expression tissues, metabolic FGF genes are subject to direct transcriptional control by several major metabolite-responsive nuclear receptors, including farnesoid X receptor (FXR), peroxisome proliferator-activated receptor α (PPARA) and γ (PPARG), carbohydrate-response element-binding protein (Ch-REBP), sterol regulatory element-binding protein-1c (SREBP1c), retinoic acid-related orphan receptor α (RORA), liver X receptor β (LXRB), vitamin D receptor (VDR) [48] [49] [50] [57] [58] [59] [60] [61] [62] [63] [64] [65] , and stress-sensing transcription factors, such as ATF4 [66] , depending on the location of specific nutrition/energy-sensing cells in specific tissues. The hepatic and pharmacological FGF21 drive multiple signal axes in multiple tissues/organs, resulting in multifaceted beneficiary metabolic effects, including promoting (green arrow) glucose, lipid, and energy homeostasis; offsetting metabolic derangements; and preventing (red long-tailed "T" sign) metaflammation, inflammatory tissue damage, and tissue-specific pathogenesis, including obesity, type 2 diabetes, fatty liver disease, metabolic syndrome, and associated comorbidities. doi = 10.1007/s11684-019-0711-y id = cord-308673-dkmpayk4 author = Ni, Li title = Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19 in Wuhan date = 2020-03-13 keywords = COVID-19; January summary = Here we report the first family case of coronavirus disease 2019 (COVID-19) confirmed in Wuhan and treated using the combination of western medicine and Chinese traditional patent medicine Shuanghuanglian oral liquid (SHL). The present report described a family case, including three cases who received western medicine and Chinese traditional patent medicine Shuanghuanglian oral liquid (SHL) treatments and achieved rapid recovery. On January 28, the patient was diagnosed of COVID-19 with positive 2019-nCoV test using nasopharyngeal swab specimen (Table 1 ) and chest CT scan showing patchy ground glass opacity in the right lower lung subpleural fields (Fig. 4) . This report described the first typical family case of COVID-19 treated using the Chinese traditional patent medicine SHL because of poor response to other treatments. All their symptoms resolved after using the Chinese traditional patent medicine SHL and rapidly recovered without obvious adverse effects when the patients showed no response and their symptoms continued to aggravate after other treatments, including IVIG (5 g per day) and dexamethasone, antibiotics, and antivirus compounds. doi = 10.1007/s11684-020-0757-x id = cord-347414-t88654wo author = Peng, Mian title = Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy date = 2020-08-06 keywords = COVID-19; patient summary = title: Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy We report the clinical and laboratory findings and successful management of seven patients with critical coronavirus disease 2019 (COVID-19) requiring mechanical ventilation (MV). Upon diagnosis with COVID-19 of critical severity, the patients were admitted to the intensive care unit, where they received early noninvasive–invasive sequential ventilation, early prone positioning, and bundle pharmacotherapy regimen, which consists of antiviral, anti-inflammation, immune-enhancing, and complication-prophylaxis medicines. Here, we report the successful management of seven critically ill patients diagnosed with COVID-19 who suffered acute respiratory failure. Good treatment outcomes can be achieved for critically ill patients with COVID-19 with early sequential noninvasive-invasive ventilation and bundle pharmacotherapy, which comprises antiviral and anti-inflammation medicines, immune system support, and prophylaxis for vascular complications. doi = 10.1007/s11684-020-0796-3 id = cord-331228-wbd0s4fo author = Shehata, Mahmoud M. title = Middle East respiratory syndrome coronavirus: a comprehensive review date = 2016-01-20 keywords = Arabia; East; MERS; Middle; Saudi; respiratory summary = authors: Shehata, Mahmoud M.; Gomaa, Mokhtar R.; Ali, Mohamed A.; Kayali, Ghazi Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formation Middle East respiratory syndrome coronavirus (MERS-CoV)-Saudi Arabia Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study First cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission Clinical features and viral diagnosis of two cases of infection with Middle East respiratory syndrome coronavirus: a report of nosocomial transmission Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia doi = 10.1007/s11684-016-0430-6 id = cord-310331-29srzbuk author = Xu, Jiuyang title = 2019 novel Coronavirus outbreak: a quiz or final exam? date = 2020-03-20 keywords = China; SARS summary = Armed with experience from previous epidemics in the last two decades, clinicians, scientists, officials, and citizens in China are all contributing to the prevention of further 2019-nCoV transmission. The 2019 novel coronavirus (2019-nCoV) outbreak is currently bringing challenges to China and the whole world. Since direct human transmission and asymptomatic infection have been revealed for 2019-nCoV [3] , health authorities in China are facing an enormous challenge on disease management and control. Realizing the severity of SARS-CoV as a respiratory virus, the detection of pneumonia of unknown origin in 2019-nCoV outbreak enabled relatively early alarm from health authorities and raised awareness for medical staff to equip personal protection methods when dealing with suspected cases. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study doi = 10.1007/s11684-020-0753-1 id = cord-253452-feb75ei4 author = Yang, Xingyue title = Systematic review for geo-authentic Lonicerae Japonicae Flos date = 2017-04-19 keywords = Flos; Japonicae; Lonicerae; authentic summary = To discuss the current situation and trend of geo-authentic Lonicerae Japonicae Flos, we searched Chinese Biomedicine Literature Database, Chinese Journal Full-text Database, Chinese Scientific Journal Full-text Database, Cochrane Central Register of Controlled Trials, Wanfang, and PubMed. We investigated all studies up to November 2015 pertaining to quality assessment, discrimination, pharmacological effects, planting or processing, or ecological system of geo-authentic Lonicerae Japonicae Flos. The table included the basic information of articles and the main information about geo-authentic Lonicerae Japonicae Flos, such as chemical fingerprint, component, discrimination, pharmacological effects, planting, and processing. All of these studies were classified into 6 parts, based on the main idea of articles, mainly discussing the following points: chemical fingerprint, component analysis, planting and processing, ecological system, pharmacological effects and safety, and discrimination between different varieties. Briefly, research shows that geo-authentic Lonicerae Japonicae Flos is mainly characterized by chemical fingerprint, component analysis, planting and processing, discrimination between varieties, ecological system, pharmacological effects, and safety and focuses on the quality assessment technology. doi = 10.1007/s11684-017-0504-0 id = cord-274477-jkjyh4cs author = Zhang, Zhiruo title = Protecting healthcare personnel from 2019-nCoV infection risks: lessons and suggestions date = 2020-03-23 keywords = HCP; PPE summary = The outbreak of a novel Coronavirus disease (COVID-19, caused by the 2019-nCoV infection) in December 2019 is one of the most severe public health emergencies since the founding of People''s Republic of China in 1949. Healthcare personnel (HCP) nationwide are facing heavy workloads and high risk of infection, especially those who care for patients at the epicenter of the outbreak, Hubei Province. Based on literature search and interviews with some HCP working at Wuhan, capital city of Hubei, we have summarized some of the effective measures taken to reduce infection among HCP, and also made suggestions for improving occupational safety during an infectious disease outbreak. The local outbreak of novel coronavirus epidemic (COVID-19, caused by the 2019-nCoV infection) in Wuhan, Hubei Province of China, last December has rapidly spread nationwide with a cumulative number of 80 026 laboratory-confirmed cases and 2912 deaths as of March 1, 2020 [1] . doi = 10.1007/s11684-020-0765-x id = cord-344480-6tcush4w author = Zhou, Guangbiao title = Back to the spring of Wuhan: facts and hope of COVID-19 outbreak date = 2020-03-14 keywords = China; Wuhan summary = The updated genome sequence of SARS-CoV-2 has been shared to the public, clinical trials are undergoing, and scientists from China and overseas are working together to combat this public health emergency. Epidemiological research priorities for public health control of the ongoing global novel coronavirus (2019-nCoV) outbreak The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Therapeutic strategies in an outbreak scenario to treat the novel coronavirus originating in Wuhan, China. doi = 10.1007/s11684-020-0758-9 id = cord-287222-wojyisu0 author = Zhou, Min title = Coronavirus disease 2019 (COVID-19): a clinical update date = 2020-04-02 keywords = COVID-19; China; MERS; SARS; Wuhan; patient summary = Of the first 99 laboratory-confirmed patients, 49 (49%) had been exposed to HSWM, which was reported to be the possible initial source of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) [5] . New Coronavirus Infection Diagnosis and Treatment Scheme (Trial Version) published by Military Support Hubei Medical Team also put forward that for mild to moderate COVID-19 patients, corticosteroids should not be given principally and highdose corticosteroid pulse therapy was not recommended. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical pathology of critical patient with novel coronavirus pneumonia (COVID-19) doi = 10.1007/s11684-020-0767-8