id author title date pages extension mime words sentences flesch summary cache txt cord-298233-qqhgmqrg Nan, Yuchen Molecular Biology and Infection of Hepatitis E Virus 2016-09-07 .txt text/plain 16449 792 47 More interestingly, a remarkable HEV strain Kernow-C1, which was originally isolated from an HIV-positive patient with chronic HEV infection, contains an insertion of a 174 nt gene fragment of human ribosomal protein S17 in the Pro region (Shukla et al., 2011) . Furthermore, other studies indicate that the expression of viral macro domain in liver cells inhibits apoptosis since it is functionally related to poly(ADP-ribose) polymerase-1 (PARP-1; Allen et al., 2003; Chen et al., 2009) , suggesting a role in apoptosis during viral infection. Identification of critical residues in hepatitis E virus macro domain involved in its interaction with viral methyltransferase and ORF3 proteins ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells The ORF2 protein of hepatitis E virus binds the 5 region of viral RNA ORF3 protein of hepatitis E virus is essential for virion release from infected cells ./cache/cord-298233-qqhgmqrg.txt ./txt/cord-298233-qqhgmqrg.txt