id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270467-es6dnx36	Frisardi, Vincenza	Commentary: Coronavirus and Obesity: Could Insulin Resistance Mediate the Severity of Covid-19 Infection?	2020-07-07		.txt	text/plain	1255	68	43	An article published on Frontiers Public Health supported the evidence of possible mechanisms linking IR and COVID-19 severity via the upregulation of ACE 2, the protein involved in virus entry (1) . We need to understand the molecular mechanisms related to the higher risk both of being infected by SARS-CoV-2 and of developing a more severe disease (COVID-19). The International Severe Acute Respiratory & Emerging Infection Consortium (ISARIC) International report of 1,123 patients with suspected or confirmed COVID-19 found that obesity was the fifth most observed comorbidity in hospitalized patientsonly somewhat less common than "high-risk" pulmonary conditions 2 . As reported from the authors, in people with obesity and diabetes, it is clear that other mechanisms independent of ACE2 expression are likely to contribute to the more severe phenotype of COVID-19. Coronavirus and obesity: could insulin resistance mediate the severity of COVID-19 infection?	./cache/cord-270467-es6dnx36.txt	./txt/cord-270467-es6dnx36.txt