id sid tid token lemma pos cord-270467-es6dnx36 1 1 key key NN cord-270467-es6dnx36 1 2 : : : cord-270467-es6dnx36 2 1 cord-270467-es6dnx36 cord-270467-es6dnx36 NN cord-270467-es6dnx36 2 2 authors author NNS cord-270467-es6dnx36 2 3 : : : cord-270467-es6dnx36 2 4 Frisardi Frisardi NNP cord-270467-es6dnx36 2 5 , , , cord-270467-es6dnx36 2 6 Vincenza Vincenza NNP cord-270467-es6dnx36 2 7 title title NN cord-270467-es6dnx36 2 8 : : : cord-270467-es6dnx36 2 9 Commentary commentary NN cord-270467-es6dnx36 2 10 : : : cord-270467-es6dnx36 2 11 Coronavirus Coronavirus NNP cord-270467-es6dnx36 2 12 and and CC cord-270467-es6dnx36 2 13 Obesity obesity NN cord-270467-es6dnx36 2 14 : : : cord-270467-es6dnx36 2 15 Could Could MD cord-270467-es6dnx36 2 16 Insulin Insulin NNP cord-270467-es6dnx36 2 17 Resistance Resistance NNP cord-270467-es6dnx36 2 18 Mediate mediate VB cord-270467-es6dnx36 2 19 the the DT cord-270467-es6dnx36 2 20 Severity severity NN cord-270467-es6dnx36 2 21 of of IN cord-270467-es6dnx36 2 22 Covid-19 covid-19 NN cord-270467-es6dnx36 2 23 Infection infection NN cord-270467-es6dnx36 2 24 ? ? . cord-270467-es6dnx36 3 1 date date NN cord-270467-es6dnx36 3 2 : : : cord-270467-es6dnx36 3 3 2020 2020 CD cord-270467-es6dnx36 3 4 - - HYPH cord-270467-es6dnx36 3 5 07 07 CD cord-270467-es6dnx36 3 6 - - HYPH cord-270467-es6dnx36 3 7 07 07 CD cord-270467-es6dnx36 3 8 journal journal NN cord-270467-es6dnx36 3 9 : : : cord-270467-es6dnx36 4 1 Front Front NNP cord-270467-es6dnx36 4 2 Public Public NNP cord-270467-es6dnx36 4 3 Health Health NNP cord-270467-es6dnx36 4 4 DOI doi NN cord-270467-es6dnx36 4 5 : : : cord-270467-es6dnx36 5 1 10.3389/ 10.3389/ CD cord-270467-es6dnx36 6 1 fpubh.2020.00351 fpubh.2020.00351 RB cord-270467-es6dnx36 7 1 sha sha NNP cord-270467-es6dnx36 7 2 : : : cord-270467-es6dnx36 7 3 fd1a3a1d21ea4e34b149686c42cd8d22ba1b48d0 fd1a3a1d21ea4e34b149686c42cd8d22ba1b48d0 CD cord-270467-es6dnx36 7 4 doc_id doc_id CD cord-270467-es6dnx36 7 5 : : : cord-270467-es6dnx36 7 6 270467 270467 CD cord-270467-es6dnx36 7 7 cord_uid cord_uid NNS cord-270467-es6dnx36 7 8 : : : cord-270467-es6dnx36 8 1 es6dnx36 es6dnx36 NNP cord-270467-es6dnx36 8 2 nan nan NNP cord-270467-es6dnx36 8 3 Insulin Insulin NNP cord-270467-es6dnx36 8 4 Resistance Resistance NNP cord-270467-es6dnx36 8 5 ( ( -LRB- cord-270467-es6dnx36 8 6 IR IR NNP cord-270467-es6dnx36 8 7 ) ) -RRB- cord-270467-es6dnx36 8 8 might may MD cord-270467-es6dnx36 8 9 be be VB cord-270467-es6dnx36 8 10 a a DT cord-270467-es6dnx36 8 11 potential potential JJ cord-270467-es6dnx36 8 12 key key JJ cord-270467-es6dnx36 8 13 factor factor NN cord-270467-es6dnx36 8 14 behind behind IN cord-270467-es6dnx36 8 15 the the DT cord-270467-es6dnx36 8 16 COVID-19 COVID-19 NNP cord-270467-es6dnx36 8 17 severity severity NN cord-270467-es6dnx36 8 18 found find VBN cord-270467-es6dnx36 8 19 in in IN cord-270467-es6dnx36 8 20 people people NNS cord-270467-es6dnx36 8 21 with with IN cord-270467-es6dnx36 8 22 obesity obesity NN cord-270467-es6dnx36 8 23 . . . cord-270467-es6dnx36 9 1 An an DT cord-270467-es6dnx36 9 2 article article NN cord-270467-es6dnx36 9 3 published publish VBN cord-270467-es6dnx36 9 4 on on IN cord-270467-es6dnx36 9 5 Frontiers Frontiers NNP cord-270467-es6dnx36 9 6 Public Public NNP cord-270467-es6dnx36 9 7 Health Health NNP cord-270467-es6dnx36 9 8 supported support VBD cord-270467-es6dnx36 9 9 the the DT cord-270467-es6dnx36 9 10 evidence evidence NN cord-270467-es6dnx36 9 11 of of IN cord-270467-es6dnx36 9 12 possible possible JJ cord-270467-es6dnx36 9 13 mechanisms mechanism NNS cord-270467-es6dnx36 9 14 linking link VBG cord-270467-es6dnx36 9 15 IR IR NNP cord-270467-es6dnx36 9 16 and and CC cord-270467-es6dnx36 9 17 COVID-19 covid-19 JJ cord-270467-es6dnx36 9 18 severity severity NN cord-270467-es6dnx36 9 19 via via IN cord-270467-es6dnx36 9 20 the the DT cord-270467-es6dnx36 9 21 upregulation upregulation NN cord-270467-es6dnx36 9 22 of of IN cord-270467-es6dnx36 9 23 ACE ace NN cord-270467-es6dnx36 9 24 2 2 CD cord-270467-es6dnx36 9 25 , , , cord-270467-es6dnx36 9 26 the the DT cord-270467-es6dnx36 9 27 protein protein NN cord-270467-es6dnx36 9 28 involved involve VBN cord-270467-es6dnx36 9 29 in in IN cord-270467-es6dnx36 9 30 virus virus NN cord-270467-es6dnx36 9 31 entry entry NN cord-270467-es6dnx36 9 32 ( ( -LRB- cord-270467-es6dnx36 9 33 1 1 CD cord-270467-es6dnx36 9 34 ) ) -RRB- cord-270467-es6dnx36 9 35 . . . cord-270467-es6dnx36 10 1 This this DT cord-270467-es6dnx36 10 2 research research NN cord-270467-es6dnx36 10 3 area area NN cord-270467-es6dnx36 10 4 is be VBZ cord-270467-es6dnx36 10 5 worthy worthy JJ cord-270467-es6dnx36 10 6 of of IN cord-270467-es6dnx36 10 7 being be VBG cord-270467-es6dnx36 10 8 investigated investigate VBN cord-270467-es6dnx36 10 9 further further RB cord-270467-es6dnx36 10 10 for for IN cord-270467-es6dnx36 10 11 its -PRON- PRP$ cord-270467-es6dnx36 10 12 implication implication NN cord-270467-es6dnx36 10 13 in in IN cord-270467-es6dnx36 10 14 the the DT cord-270467-es6dnx36 10 15 prevention prevention NN cord-270467-es6dnx36 10 16 and and CC cord-270467-es6dnx36 10 17 treatment treatment NN cord-270467-es6dnx36 10 18 of of IN cord-270467-es6dnx36 10 19 this this DT cord-270467-es6dnx36 10 20 dramatic dramatic JJ cord-270467-es6dnx36 10 21 pandemic pandemic NN cord-270467-es6dnx36 10 22 . . . cord-270467-es6dnx36 11 1 We -PRON- PRP cord-270467-es6dnx36 11 2 need need VBP cord-270467-es6dnx36 11 3 to to TO cord-270467-es6dnx36 11 4 understand understand VB cord-270467-es6dnx36 11 5 the the DT cord-270467-es6dnx36 11 6 molecular molecular JJ cord-270467-es6dnx36 11 7 mechanisms mechanism NNS cord-270467-es6dnx36 11 8 related relate VBN cord-270467-es6dnx36 11 9 to to IN cord-270467-es6dnx36 11 10 the the DT cord-270467-es6dnx36 11 11 higher high JJR cord-270467-es6dnx36 11 12 risk risk NN cord-270467-es6dnx36 11 13 both both DT cord-270467-es6dnx36 11 14 of of IN cord-270467-es6dnx36 11 15 being be VBG cord-270467-es6dnx36 11 16 infected infect VBN cord-270467-es6dnx36 11 17 by by IN cord-270467-es6dnx36 11 18 SARS SARS NNP cord-270467-es6dnx36 11 19 - - HYPH cord-270467-es6dnx36 11 20 CoV-2 CoV-2 NNP cord-270467-es6dnx36 11 21 and and CC cord-270467-es6dnx36 11 22 of of IN cord-270467-es6dnx36 11 23 developing develop VBG cord-270467-es6dnx36 11 24 a a DT cord-270467-es6dnx36 11 25 more more RBR cord-270467-es6dnx36 11 26 severe severe JJ cord-270467-es6dnx36 11 27 disease disease NN cord-270467-es6dnx36 11 28 ( ( -LRB- cord-270467-es6dnx36 11 29 COVID-19 COVID-19 NNP cord-270467-es6dnx36 11 30 ) ) -RRB- cord-270467-es6dnx36 11 31 . . . cord-270467-es6dnx36 12 1 Recent recent JJ cord-270467-es6dnx36 12 2 reports report NNS cord-270467-es6dnx36 12 3 of of IN cord-270467-es6dnx36 12 4 hospitalized hospitalize VBN cord-270467-es6dnx36 12 5 COVID-19 covid-19 CD cord-270467-es6dnx36 12 6 patients patient NNS cord-270467-es6dnx36 12 7 have have VBP cord-270467-es6dnx36 12 8 found find VBN cord-270467-es6dnx36 12 9 obesity obesity NN cord-270467-es6dnx36 12 10 to to TO cord-270467-es6dnx36 12 11 be be VB cord-270467-es6dnx36 12 12 a a DT cord-270467-es6dnx36 12 13 risk risk NN cord-270467-es6dnx36 12 14 factor factor NN cord-270467-es6dnx36 12 15 for for IN cord-270467-es6dnx36 12 16 the the DT cord-270467-es6dnx36 12 17 worst bad JJS cord-270467-es6dnx36 12 18 adverse adverse JJ cord-270467-es6dnx36 12 19 outcomes outcome NNS cord-270467-es6dnx36 12 20 ( ( -LRB- cord-270467-es6dnx36 12 21 severity severity NN cord-270467-es6dnx36 12 22 and and CC cord-270467-es6dnx36 12 23 mortality mortality NN cord-270467-es6dnx36 12 24 ) ) -RRB- cord-270467-es6dnx36 12 25 . . . cord-270467-es6dnx36 13 1 The the DT cord-270467-es6dnx36 13 2 Intensive Intensive NNP cord-270467-es6dnx36 13 3 Care Care NNP cord-270467-es6dnx36 13 4 National National NNP cord-270467-es6dnx36 13 5 Audit Audit NNP cord-270467-es6dnx36 13 6 and and CC cord-270467-es6dnx36 13 7 Research Research NNP cord-270467-es6dnx36 13 8 Centre Centre NNP cord-270467-es6dnx36 13 9 ( ( -LRB- cord-270467-es6dnx36 13 10 ICNARC ICNARC NNP cord-270467-es6dnx36 13 11 ) ) -RRB- cord-270467-es6dnx36 13 12 report report VBP cord-270467-es6dnx36 13 13 on on IN cord-270467-es6dnx36 13 14 2,621 2,621 CD cord-270467-es6dnx36 13 15 patients patient NNS cord-270467-es6dnx36 13 16 in in IN cord-270467-es6dnx36 13 17 intensive intensive JJ cord-270467-es6dnx36 13 18 care care NN cord-270467-es6dnx36 13 19 units unit NNS cord-270467-es6dnx36 13 20 in in IN cord-270467-es6dnx36 13 21 England England NNP cord-270467-es6dnx36 13 22 showed show VBD cord-270467-es6dnx36 13 23 that that IN cord-270467-es6dnx36 13 24 the the DT cord-270467-es6dnx36 13 25 case case NN cord-270467-es6dnx36 13 26 fatality fatality NN cord-270467-es6dnx36 13 27 rate rate NN cord-270467-es6dnx36 13 28 was be VBD cord-270467-es6dnx36 13 29 higher high JJR cord-270467-es6dnx36 13 30 in in IN cord-270467-es6dnx36 13 31 obese obese JJ cord-270467-es6dnx36 13 32 patients patient NNS cord-270467-es6dnx36 13 33 1 1 CD cord-270467-es6dnx36 13 34 . . . cord-270467-es6dnx36 14 1 The the DT cord-270467-es6dnx36 14 2 International International NNP cord-270467-es6dnx36 14 3 Severe Severe NNP cord-270467-es6dnx36 14 4 Acute Acute NNP cord-270467-es6dnx36 14 5 Respiratory Respiratory NNP cord-270467-es6dnx36 14 6 & & CC cord-270467-es6dnx36 14 7 Emerging Emerging NNP cord-270467-es6dnx36 14 8 Infection Infection NNP cord-270467-es6dnx36 14 9 Consortium Consortium NNP cord-270467-es6dnx36 14 10 ( ( -LRB- cord-270467-es6dnx36 14 11 ISARIC ISARIC NNP cord-270467-es6dnx36 14 12 ) ) -RRB- cord-270467-es6dnx36 15 1 International international JJ cord-270467-es6dnx36 15 2 report report NN cord-270467-es6dnx36 15 3 of of IN cord-270467-es6dnx36 15 4 1,123 1,123 CD cord-270467-es6dnx36 15 5 patients patient NNS cord-270467-es6dnx36 15 6 with with IN cord-270467-es6dnx36 15 7 suspected suspect VBN cord-270467-es6dnx36 15 8 or or CC cord-270467-es6dnx36 15 9 confirmed confirm VBN cord-270467-es6dnx36 15 10 COVID-19 COVID-19 NNP cord-270467-es6dnx36 15 11 found find VBD cord-270467-es6dnx36 15 12 that that IN cord-270467-es6dnx36 15 13 obesity obesity NN cord-270467-es6dnx36 15 14 was be VBD cord-270467-es6dnx36 15 15 the the DT cord-270467-es6dnx36 15 16 fifth fifth JJ cord-270467-es6dnx36 15 17 most most RBS cord-270467-es6dnx36 15 18 observed observed JJ cord-270467-es6dnx36 15 19 comorbidity comorbidity NN cord-270467-es6dnx36 15 20 in in IN cord-270467-es6dnx36 15 21 hospitalized hospitalize VBN cord-270467-es6dnx36 15 22 patientsonly patientsonly NN cord-270467-es6dnx36 15 23 somewhat somewhat RB cord-270467-es6dnx36 15 24 less less RBR cord-270467-es6dnx36 15 25 common common JJ cord-270467-es6dnx36 15 26 than than IN cord-270467-es6dnx36 15 27 " " `` cord-270467-es6dnx36 15 28 high high JJ cord-270467-es6dnx36 15 29 - - HYPH cord-270467-es6dnx36 15 30 risk risk NN cord-270467-es6dnx36 15 31 " " `` cord-270467-es6dnx36 15 32 pulmonary pulmonary JJ cord-270467-es6dnx36 15 33 conditions condition NNS cord-270467-es6dnx36 15 34 2 2 CD cord-270467-es6dnx36 15 35 . . . cord-270467-es6dnx36 16 1 Systematic systematic JJ cord-270467-es6dnx36 16 2 reviews review NNS cord-270467-es6dnx36 16 3 and and CC cord-270467-es6dnx36 16 4 meta meta NNP cord-270467-es6dnx36 16 5 - - HYPH cord-270467-es6dnx36 16 6 analyses analysis NNS cord-270467-es6dnx36 16 7 confirmed confirm VBD cord-270467-es6dnx36 16 8 , , , cord-270467-es6dnx36 16 9 surprisingly surprisingly RB cord-270467-es6dnx36 16 10 , , , cord-270467-es6dnx36 16 11 that that IN cord-270467-es6dnx36 16 12 metabolic metabolic JJ cord-270467-es6dnx36 16 13 disorders disorder NNS cord-270467-es6dnx36 16 14 seem seem VBP cord-270467-es6dnx36 16 15 to to TO cord-270467-es6dnx36 16 16 play play VB cord-270467-es6dnx36 16 17 a a DT cord-270467-es6dnx36 16 18 more more RBR cord-270467-es6dnx36 16 19 pivotal pivotal JJ cord-270467-es6dnx36 16 20 role role NN cord-270467-es6dnx36 16 21 for for IN cord-270467-es6dnx36 16 22 negative negative JJ cord-270467-es6dnx36 16 23 outcomes outcome NNS cord-270467-es6dnx36 16 24 in in IN cord-270467-es6dnx36 16 25 COVID-19 covid-19 NN cord-270467-es6dnx36 16 26 compared compare VBN cord-270467-es6dnx36 16 27 with with IN cord-270467-es6dnx36 16 28 preexistent preexistent JJ cord-270467-es6dnx36 16 29 chronic chronic JJ cord-270467-es6dnx36 16 30 respiratory respiratory JJ cord-270467-es6dnx36 16 31 disease disease NN cord-270467-es6dnx36 16 32 ( ( -LRB- cord-270467-es6dnx36 16 33 2 2 CD cord-270467-es6dnx36 16 34 ) ) -RRB- cord-270467-es6dnx36 16 35 . . . cord-270467-es6dnx36 17 1 Starting start VBG cord-270467-es6dnx36 17 2 from from IN cord-270467-es6dnx36 17 3 this this DT cord-270467-es6dnx36 17 4 , , , cord-270467-es6dnx36 17 5 it -PRON- PRP cord-270467-es6dnx36 17 6 would would MD cord-270467-es6dnx36 17 7 be be VB cord-270467-es6dnx36 17 8 appropriate appropriate JJ cord-270467-es6dnx36 17 9 to to TO cord-270467-es6dnx36 17 10 think think VB cord-270467-es6dnx36 17 11 of of IN cord-270467-es6dnx36 17 12 obesity obesity NN cord-270467-es6dnx36 17 13 in in IN cord-270467-es6dnx36 17 14 relation relation NN cord-270467-es6dnx36 17 15 to to IN cord-270467-es6dnx36 17 16 COVID-19 covid-19 JJ cord-270467-es6dnx36 17 17 outcome outcome NN cord-270467-es6dnx36 17 18 in in IN cord-270467-es6dnx36 17 19 a a DT cord-270467-es6dnx36 17 20 more more RBR cord-270467-es6dnx36 17 21 complex complex JJ cord-270467-es6dnx36 17 22 way way NN cord-270467-es6dnx36 17 23 , , , cord-270467-es6dnx36 17 24 rather rather RB cord-270467-es6dnx36 17 25 than than IN cord-270467-es6dnx36 17 26 considering consider VBG cord-270467-es6dnx36 17 27 only only RB cord-270467-es6dnx36 17 28 the the DT cord-270467-es6dnx36 17 29 mechanical mechanical JJ cord-270467-es6dnx36 17 30 effects effect NNS cord-270467-es6dnx36 17 31 of of IN cord-270467-es6dnx36 17 32 abdominal abdominal JJ cord-270467-es6dnx36 17 33 compression compression NN cord-270467-es6dnx36 17 34 on on IN cord-270467-es6dnx36 17 35 the the DT cord-270467-es6dnx36 17 36 respiratory respiratory JJ cord-270467-es6dnx36 17 37 dynamic dynamic NN cord-270467-es6dnx36 17 38 . . . cord-270467-es6dnx36 18 1 Finucane Finucane NNP cord-270467-es6dnx36 18 2 and and CC cord-270467-es6dnx36 18 3 Davenport Davenport NNP cord-270467-es6dnx36 18 4 argued argue VBD cord-270467-es6dnx36 18 5 that that IN cord-270467-es6dnx36 18 6 the the DT cord-270467-es6dnx36 18 7 insulin insulin NN cord-270467-es6dnx36 18 8 - - HYPH cord-270467-es6dnx36 18 9 mediated mediate VBN cord-270467-es6dnx36 18 10 metabolic metabolic JJ cord-270467-es6dnx36 18 11 and and CC cord-270467-es6dnx36 18 12 inflammatory inflammatory JJ cord-270467-es6dnx36 18 13 processes process NNS cord-270467-es6dnx36 18 14 could could MD cord-270467-es6dnx36 18 15 be be VB cord-270467-es6dnx36 18 16 the the DT cord-270467-es6dnx36 18 17 cause cause NN cord-270467-es6dnx36 18 18 of of IN cord-270467-es6dnx36 18 19 the the DT cord-270467-es6dnx36 18 20 negative negative JJ cord-270467-es6dnx36 18 21 SARS SARS NNP cord-270467-es6dnx36 18 22 - - HYPH cord-270467-es6dnx36 18 23 CoV2-related CoV2-related NNP cord-270467-es6dnx36 18 24 trajectory trajectory NN cord-270467-es6dnx36 18 25 in in IN cord-270467-es6dnx36 18 26 obese obese JJ cord-270467-es6dnx36 18 27 patients patient NNS cord-270467-es6dnx36 18 28 . . . cord-270467-es6dnx36 19 1 In in IN cord-270467-es6dnx36 19 2 the the DT cord-270467-es6dnx36 19 3 last last JJ cord-270467-es6dnx36 19 4 few few JJ cord-270467-es6dnx36 19 5 decades decade NNS cord-270467-es6dnx36 19 6 , , , cord-270467-es6dnx36 19 7 insulin insulin NN cord-270467-es6dnx36 19 8 was be VBD cord-270467-es6dnx36 19 9 believed believe VBN cord-270467-es6dnx36 19 10 to to TO cord-270467-es6dnx36 19 11 intervene intervene VB cord-270467-es6dnx36 19 12 in in IN cord-270467-es6dnx36 19 13 other other JJ cord-270467-es6dnx36 19 14 degenerative degenerative JJ cord-270467-es6dnx36 19 15 diseases disease NNS cord-270467-es6dnx36 19 16 both both DT cord-270467-es6dnx36 19 17 as as IN cord-270467-es6dnx36 19 18 a a DT cord-270467-es6dnx36 19 19 principal principal JJ cord-270467-es6dnx36 19 20 leading lead VBG cord-270467-es6dnx36 19 21 factor factor NN cord-270467-es6dnx36 19 22 and and CC cord-270467-es6dnx36 19 23 in in IN cord-270467-es6dnx36 19 24 a a DT cord-270467-es6dnx36 19 25 cross cross NN cord-270467-es6dnx36 19 26 - - NN cord-270467-es6dnx36 19 27 talk talk NN cord-270467-es6dnx36 19 28 with with IN cord-270467-es6dnx36 19 29 other other JJ cord-270467-es6dnx36 19 30 metabolic metabolic JJ cord-270467-es6dnx36 19 31 disorders disorder NNS cord-270467-es6dnx36 19 32 ( ( -LRB- cord-270467-es6dnx36 19 33 3 3 CD cord-270467-es6dnx36 19 34 , , , cord-270467-es6dnx36 19 35 4 4 CD cord-270467-es6dnx36 19 36 ) ) -RRB- cord-270467-es6dnx36 19 37 . . . cord-270467-es6dnx36 20 1 Because because IN cord-270467-es6dnx36 20 2 obesity obesity NN cord-270467-es6dnx36 20 3 and and CC cord-270467-es6dnx36 20 4 IR IR NNP cord-270467-es6dnx36 20 5 have have VB cord-270467-es6dnx36 20 6 a a DT cord-270467-es6dnx36 20 7 bidirectional bidirectional JJ cord-270467-es6dnx36 20 8 relationship relationship NN cord-270467-es6dnx36 20 9 and and CC cord-270467-es6dnx36 20 10 the the DT cord-270467-es6dnx36 20 11 adiposeinsulin adiposeinsulin NNP cord-270467-es6dnx36 20 12 axis axis NN cord-270467-es6dnx36 20 13 was be VBD cord-270467-es6dnx36 20 14 postulated postulate VBN cord-270467-es6dnx36 20 15 ( ( -LRB- cord-270467-es6dnx36 20 16 5 5 CD cord-270467-es6dnx36 20 17 , , , cord-270467-es6dnx36 20 18 6 6 CD cord-270467-es6dnx36 20 19 ) ) -RRB- cord-270467-es6dnx36 20 20 , , , cord-270467-es6dnx36 20 21 the the DT cord-270467-es6dnx36 20 22 research research NN cord-270467-es6dnx36 20 23 needs need VBZ cord-270467-es6dnx36 20 24 to to TO cord-270467-es6dnx36 20 25 be be VB cord-270467-es6dnx36 20 26 more more RBR cord-270467-es6dnx36 20 27 addressed address VBN cord-270467-es6dnx36 20 28 toward toward IN cord-270467-es6dnx36 20 29 the the DT cord-270467-es6dnx36 20 30 convoluted convoluted JJ cord-270467-es6dnx36 20 31 route route NN cord-270467-es6dnx36 20 32 linking link VBG cord-270467-es6dnx36 20 33 lipid lipid NN cord-270467-es6dnx36 20 34 and and CC cord-270467-es6dnx36 20 35 glucose glucose NN cord-270467-es6dnx36 20 36 metabolism metabolism NN cord-270467-es6dnx36 20 37 as as IN cord-270467-es6dnx36 20 38 a a DT cord-270467-es6dnx36 20 39 unique unique JJ cord-270467-es6dnx36 20 40 molecular molecular JJ cord-270467-es6dnx36 20 41 platoon platoon NN cord-270467-es6dnx36 20 42 . . . cord-270467-es6dnx36 21 1 Insulin insulin NN cord-270467-es6dnx36 21 2 is be VBZ cord-270467-es6dnx36 21 3 a a DT cord-270467-es6dnx36 21 4 critical critical JJ cord-270467-es6dnx36 21 5 regulator regulator NN cord-270467-es6dnx36 21 6 of of IN cord-270467-es6dnx36 21 7 many many JJ cord-270467-es6dnx36 21 8 cellular cellular JJ cord-270467-es6dnx36 21 9 pathways pathway NNS cord-270467-es6dnx36 21 10 , , , cord-270467-es6dnx36 21 11 with with IN cord-270467-es6dnx36 21 12 many many JJ cord-270467-es6dnx36 21 13 already already RB cord-270467-es6dnx36 21 14 demonstrated demonstrate VBN cord-270467-es6dnx36 21 15 tissue tissue NN cord-270467-es6dnx36 21 16 - - HYPH cord-270467-es6dnx36 21 17 specific specific JJ cord-270467-es6dnx36 21 18 actions action NNS cord-270467-es6dnx36 21 19 . . . cord-270467-es6dnx36 22 1 Rapid rapid JJ cord-270467-es6dnx36 22 2 changes change NNS cord-270467-es6dnx36 22 3 in in IN cord-270467-es6dnx36 22 4 protein protein NN cord-270467-es6dnx36 22 5 phosphorylation phosphorylation NN cord-270467-es6dnx36 22 6 and and CC cord-270467-es6dnx36 22 7 function function VB cord-270467-es6dnx36 22 8 as as RB cord-270467-es6dnx36 22 9 well well RB cord-270467-es6dnx36 22 10 as as IN cord-270467-es6dnx36 22 11 changes change NNS cord-270467-es6dnx36 22 12 in in IN cord-270467-es6dnx36 22 13 gene gene NN cord-270467-es6dnx36 22 14 expression expression NN cord-270467-es6dnx36 22 15 mediate mediate VB cord-270467-es6dnx36 22 16 the the DT cord-270467-es6dnx36 22 17 insulin insulin NN cord-270467-es6dnx36 22 18 - - HYPH cord-270467-es6dnx36 22 19 related relate VBN cord-270467-es6dnx36 22 20 metabolic metabolic JJ cord-270467-es6dnx36 22 21 effects effect NNS cord-270467-es6dnx36 22 22 ( ( -LRB- cord-270467-es6dnx36 22 23 6 6 CD cord-270467-es6dnx36 22 24 ) ) -RRB- cord-270467-es6dnx36 22 25 . . . cord-270467-es6dnx36 23 1 Finucane Finucane NNP cord-270467-es6dnx36 23 2 and and CC cord-270467-es6dnx36 23 3 Davenport Davenport NNP cord-270467-es6dnx36 23 4 reported report VBD cord-270467-es6dnx36 23 5 the the DT cord-270467-es6dnx36 23 6 evidence evidence NN cord-270467-es6dnx36 23 7 that that WDT cord-270467-es6dnx36 23 8 insulinmediated insulinmediate VBD cord-270467-es6dnx36 23 9 ACE2 ACE2 NNP cord-270467-es6dnx36 23 10 expression expression NN cord-270467-es6dnx36 23 11 varies vary VBZ cord-270467-es6dnx36 23 12 in in IN cord-270467-es6dnx36 23 13 a a DT cord-270467-es6dnx36 23 14 tissue tissue NN cord-270467-es6dnx36 23 15 - - HYPH cord-270467-es6dnx36 23 16 specific specific JJ cord-270467-es6dnx36 23 17 manner manner NN cord-270467-es6dnx36 23 18 with with IN cord-270467-es6dnx36 23 19 significant significant JJ cord-270467-es6dnx36 23 20 expression expression NN cord-270467-es6dnx36 23 21 in in IN cord-270467-es6dnx36 23 22 the the DT cord-270467-es6dnx36 23 23 lungs lung NNS cord-270467-es6dnx36 23 24 . . . cord-270467-es6dnx36 24 1 Whether whether IN cord-270467-es6dnx36 24 2 the the DT cord-270467-es6dnx36 24 3 high high JJ cord-270467-es6dnx36 24 4 glucose glucose NN cord-270467-es6dnx36 24 5 level level NN cord-270467-es6dnx36 24 6 rather rather RB cord-270467-es6dnx36 24 7 than than IN cord-270467-es6dnx36 24 8 elevated elevated JJ cord-270467-es6dnx36 24 9 insulin insulin NN cord-270467-es6dnx36 24 10 levels level NNS cord-270467-es6dnx36 24 11 is be VBZ cord-270467-es6dnx36 24 12 responsible responsible JJ cord-270467-es6dnx36 24 13 for for IN cord-270467-es6dnx36 24 14 this this DT cord-270467-es6dnx36 24 15 overexpression overexpression NN cord-270467-es6dnx36 24 16 is be VBZ cord-270467-es6dnx36 24 17 worthy worthy JJ cord-270467-es6dnx36 24 18 of of IN cord-270467-es6dnx36 24 19 investigation investigation NN cord-270467-es6dnx36 24 20 because because IN cord-270467-es6dnx36 24 21 it -PRON- PRP cord-270467-es6dnx36 24 22 might may MD cord-270467-es6dnx36 24 23 have have VB cord-270467-es6dnx36 24 24 clinical clinical JJ cord-270467-es6dnx36 24 25 relevance relevance NN cord-270467-es6dnx36 24 26 . . . cord-270467-es6dnx36 25 1 As as IN cord-270467-es6dnx36 25 2 reported report VBN cord-270467-es6dnx36 25 3 from from IN cord-270467-es6dnx36 25 4 the the DT cord-270467-es6dnx36 25 5 authors author NNS cord-270467-es6dnx36 25 6 , , , cord-270467-es6dnx36 25 7 in in IN cord-270467-es6dnx36 25 8 people people NNS cord-270467-es6dnx36 25 9 with with IN cord-270467-es6dnx36 25 10 obesity obesity NN cord-270467-es6dnx36 25 11 and and CC cord-270467-es6dnx36 25 12 diabetes diabetes NN cord-270467-es6dnx36 25 13 , , , cord-270467-es6dnx36 25 14 it -PRON- PRP cord-270467-es6dnx36 25 15 is be VBZ cord-270467-es6dnx36 25 16 clear clear JJ cord-270467-es6dnx36 25 17 that that IN cord-270467-es6dnx36 25 18 other other JJ cord-270467-es6dnx36 25 19 mechanisms mechanism NNS cord-270467-es6dnx36 25 20 independent independent JJ cord-270467-es6dnx36 25 21 of of IN cord-270467-es6dnx36 25 22 ACE2 ACE2 NNP cord-270467-es6dnx36 25 23 expression expression NN cord-270467-es6dnx36 25 24 are be VBP cord-270467-es6dnx36 25 25 likely likely JJ cord-270467-es6dnx36 25 26 to to TO cord-270467-es6dnx36 25 27 contribute contribute VB cord-270467-es6dnx36 25 28 to to IN cord-270467-es6dnx36 25 29 the the DT cord-270467-es6dnx36 25 30 more more RBR cord-270467-es6dnx36 25 31 severe severe JJ cord-270467-es6dnx36 25 32 phenotype phenotype NN cord-270467-es6dnx36 25 33 of of IN cord-270467-es6dnx36 25 34 COVID-19 COVID-19 NNP cord-270467-es6dnx36 25 35 . . . cord-270467-es6dnx36 26 1 The the DT cord-270467-es6dnx36 26 2 clinical clinical JJ cord-270467-es6dnx36 26 3 manifestations manifestation NNS cord-270467-es6dnx36 26 4 of of IN cord-270467-es6dnx36 26 5 COVID-19 COVID-19 NNP cord-270467-es6dnx36 26 6 are be VBP cord-270467-es6dnx36 26 7 heterogeneous heterogeneous JJ cord-270467-es6dnx36 26 8 , , , cord-270467-es6dnx36 26 9 with with IN cord-270467-es6dnx36 26 10 the the DT cord-270467-es6dnx36 26 11 lungs lung NNS cord-270467-es6dnx36 26 12 the the DT cord-270467-es6dnx36 26 13 most most RBS cord-270467-es6dnx36 26 14 triggered trigger VBN cord-270467-es6dnx36 26 15 organ organ NN cord-270467-es6dnx36 26 16 . . . cord-270467-es6dnx36 27 1 Nevertheless nevertheless RB cord-270467-es6dnx36 27 2 , , , cord-270467-es6dnx36 27 3 other other JJ cord-270467-es6dnx36 27 4 clinical clinical JJ cord-270467-es6dnx36 27 5 expressions expression NNS cord-270467-es6dnx36 27 6 of of IN cord-270467-es6dnx36 27 7 SARS SARS NNP cord-270467-es6dnx36 27 8 - - HYPH cord-270467-es6dnx36 27 9 CoV2 CoV2 NNP cord-270467-es6dnx36 27 10 were be VBD cord-270467-es6dnx36 27 11 reported report VBN cord-270467-es6dnx36 27 12 , , , cord-270467-es6dnx36 27 13 suggesting suggest VBG cord-270467-es6dnx36 27 14 an an DT cord-270467-es6dnx36 27 15 interesting interesting JJ cord-270467-es6dnx36 27 16 hypothesis hypothesis NN cord-270467-es6dnx36 27 17 about about IN cord-270467-es6dnx36 27 18 the the DT cord-270467-es6dnx36 27 19 host host NN cord-270467-es6dnx36 27 20 - - HYPH cord-270467-es6dnx36 27 21 pathogen pathogen NN cord-270467-es6dnx36 27 22 interaction interaction NN cord-270467-es6dnx36 27 23 via via IN cord-270467-es6dnx36 27 24 the the DT cord-270467-es6dnx36 27 25 metabolism metabolism NN cord-270467-es6dnx36 27 26 1 1 CD cord-270467-es6dnx36 27 27 . . . cord-270467-es6dnx36 28 1 TMPRSS2 TMPRSS2 NNP cord-270467-es6dnx36 28 2 , , , cord-270467-es6dnx36 28 3 the the DT cord-270467-es6dnx36 28 4 most most RBS cord-270467-es6dnx36 28 5 accused accuse VBN cord-270467-es6dnx36 28 6 protein protein NN cord-270467-es6dnx36 28 7 involved involve VBN cord-270467-es6dnx36 28 8 in in IN cord-270467-es6dnx36 28 9 virus virus NN cord-270467-es6dnx36 28 10 activation activation NN cord-270467-es6dnx36 28 11 , , , cord-270467-es6dnx36 28 12 has have VBZ cord-270467-es6dnx36 28 13 also also RB cord-270467-es6dnx36 28 14 been be VBN cord-270467-es6dnx36 28 15 detected detect VBN cord-270467-es6dnx36 28 16 in in IN cord-270467-es6dnx36 28 17 other other JJ cord-270467-es6dnx36 28 18 tissues tissue NNS cord-270467-es6dnx36 28 19 playing play VBG cord-270467-es6dnx36 28 20 a a DT cord-270467-es6dnx36 28 21 metabolic metabolic JJ cord-270467-es6dnx36 28 22 role role NN cord-270467-es6dnx36 28 23 , , , cord-270467-es6dnx36 28 24 in in IN cord-270467-es6dnx36 28 25 particular particular JJ cord-270467-es6dnx36 28 26 in in IN cord-270467-es6dnx36 28 27 bile bile NN cord-270467-es6dnx36 28 28 ducts duct NNS cord-270467-es6dnx36 28 29 and and CC cord-270467-es6dnx36 28 30 the the DT cord-270467-es6dnx36 28 31 pancreas pancrea NNS cord-270467-es6dnx36 28 32 ( ( -LRB- cord-270467-es6dnx36 28 33 7 7 CD cord-270467-es6dnx36 28 34 ) ) -RRB- cord-270467-es6dnx36 28 35 . . . cord-270467-es6dnx36 29 1 Furthermore furthermore RB cord-270467-es6dnx36 29 2 , , , cord-270467-es6dnx36 29 3 adipose adipose JJ cord-270467-es6dnx36 29 4 tissue tissue NN cord-270467-es6dnx36 29 5 is be VBZ cord-270467-es6dnx36 29 6 not not RB cord-270467-es6dnx36 29 7 only only RB cord-270467-es6dnx36 29 8 a a DT cord-270467-es6dnx36 29 9 simple simple JJ cord-270467-es6dnx36 29 10 fat fat NN cord-270467-es6dnx36 29 11 store store NN cord-270467-es6dnx36 29 12 tissue tissue NN cord-270467-es6dnx36 29 13 , , , cord-270467-es6dnx36 29 14 but but CC cord-270467-es6dnx36 29 15 is be VBZ cord-270467-es6dnx36 29 16 also also RB cord-270467-es6dnx36 29 17 a a DT cord-270467-es6dnx36 29 18 somewhat somewhat RB cord-270467-es6dnx36 29 19 active active JJ cord-270467-es6dnx36 29 20 endocrine endocrine JJ cord-270467-es6dnx36 29 21 organ organ NN cord-270467-es6dnx36 29 22 . . . cord-270467-es6dnx36 30 1 Gender gender NN cord-270467-es6dnx36 30 2 and and CC cord-270467-es6dnx36 30 3 age age NN cord-270467-es6dnx36 30 4 differences difference NNS cord-270467-es6dnx36 30 5 in in IN cord-270467-es6dnx36 30 6 peptides peptide NNS cord-270467-es6dnx36 30 7 and and CC cord-270467-es6dnx36 30 8 hormones hormone NNS cord-270467-es6dnx36 30 9 secreted secrete VBN cord-270467-es6dnx36 30 10 were be VBD cord-270467-es6dnx36 30 11 also also RB cord-270467-es6dnx36 30 12 reported report VBN cord-270467-es6dnx36 30 13 ( ( -LRB- cord-270467-es6dnx36 30 14 5 5 CD cord-270467-es6dnx36 30 15 ) ) -RRB- cord-270467-es6dnx36 30 16 . . . cord-270467-es6dnx36 31 1 Likely likely RB cord-270467-es6dnx36 31 2 , , , cord-270467-es6dnx36 31 3 this this DT cord-270467-es6dnx36 31 4 might may MD cord-270467-es6dnx36 31 5 explain explain VB cord-270467-es6dnx36 31 6 why why WRB cord-270467-es6dnx36 31 7 older old JJR cord-270467-es6dnx36 31 8 people people NNS cord-270467-es6dnx36 31 9 and and CC cord-270467-es6dnx36 31 10 males male NNS cord-270467-es6dnx36 31 11 are be VBP cord-270467-es6dnx36 31 12 more more JJR cord-270467-es6dnx36 31 13 at at IN cord-270467-es6dnx36 31 14 risk risk NN cord-270467-es6dnx36 31 15 of of IN cord-270467-es6dnx36 31 16 developing develop VBG cord-270467-es6dnx36 31 17 a a DT cord-270467-es6dnx36 31 18 negative negative JJ cord-270467-es6dnx36 31 19 outcome outcome NN cord-270467-es6dnx36 31 20 . . . cord-270467-es6dnx36 32 1 Lipids lipid NNS cord-270467-es6dnx36 32 2 are be VBP cord-270467-es6dnx36 32 3 structural structural JJ cord-270467-es6dnx36 32 4 elements element NNS cord-270467-es6dnx36 32 5 of of IN cord-270467-es6dnx36 32 6 viral viral JJ cord-270467-es6dnx36 32 7 and and CC cord-270467-es6dnx36 32 8 cellular cellular JJ cord-270467-es6dnx36 32 9 membranes membrane NNS cord-270467-es6dnx36 32 10 . . . cord-270467-es6dnx36 33 1 Viruses virus NNS cord-270467-es6dnx36 33 2 induce induce VBP cord-270467-es6dnx36 33 3 the the DT cord-270467-es6dnx36 33 4 formation formation NN cord-270467-es6dnx36 33 5 of of IN cord-270467-es6dnx36 33 6 novel novel JJ cord-270467-es6dnx36 33 7 cytoplasmic cytoplasmic JJ cord-270467-es6dnx36 33 8 membrane membrane NN cord-270467-es6dnx36 33 9 structures structure NNS cord-270467-es6dnx36 33 10 and and CC cord-270467-es6dnx36 33 11 compartments compartment NNS cord-270467-es6dnx36 33 12 , , , cord-270467-es6dnx36 33 13 in in IN cord-270467-es6dnx36 33 14 which which WDT cord-270467-es6dnx36 33 15 viral viral JJ cord-270467-es6dnx36 33 16 genome genome NN cord-270467-es6dnx36 33 17 replication replication NN cord-270467-es6dnx36 33 18 and and CC cord-270467-es6dnx36 33 19 assembly assembly NN cord-270467-es6dnx36 33 20 occurs occur VBZ cord-270467-es6dnx36 33 21 with with IN cord-270467-es6dnx36 33 22 , , , cord-270467-es6dnx36 33 23 in in IN cord-270467-es6dnx36 33 24 some some DT cord-270467-es6dnx36 33 25 cases case NNS cord-270467-es6dnx36 33 26 , , , cord-270467-es6dnx36 33 27 shielding shield VBG cord-270467-es6dnx36 33 28 from from IN cord-270467-es6dnx36 33 29 host host NN cord-270467-es6dnx36 33 30 innate innate JJ cord-270467-es6dnx36 33 31 immune immune JJ cord-270467-es6dnx36 33 32 response response NN cord-270467-es6dnx36 33 33 . . . cord-270467-es6dnx36 34 1 For for IN cord-270467-es6dnx36 34 2 instance instance NN cord-270467-es6dnx36 34 3 , , , cord-270467-es6dnx36 34 4 several several JJ cord-270467-es6dnx36 34 5 enveloped envelop VBN cord-270467-es6dnx36 34 6 and and CC cord-270467-es6dnx36 34 7 non non JJ cord-270467-es6dnx36 34 8 - - JJ cord-270467-es6dnx36 34 9 enveloped enveloped JJ cord-270467-es6dnx36 34 10 viruses virus NNS cord-270467-es6dnx36 34 11 are be VBP cord-270467-es6dnx36 34 12 cholesterol cholesterol NN cord-270467-es6dnx36 34 13 - - HYPH cord-270467-es6dnx36 34 14 dependent dependent JJ cord-270467-es6dnx36 34 15 for for IN cord-270467-es6dnx36 34 16 entry entry NN cord-270467-es6dnx36 34 17 into into IN cord-270467-es6dnx36 34 18 cells cell NNS cord-270467-es6dnx36 34 19 and and CC cord-270467-es6dnx36 34 20 their -PRON- PRP$ cord-270467-es6dnx36 34 21 replication replication NN cord-270467-es6dnx36 34 22 ( ( -LRB- cord-270467-es6dnx36 34 23 8) 8) NN cord-270467-es6dnx36 34 24 . . . cord-270467-es6dnx36 35 1 Moreover moreover RB cord-270467-es6dnx36 35 2 , , , cord-270467-es6dnx36 35 3 the the DT cord-270467-es6dnx36 35 4 sterol sterol NN cord-270467-es6dnx36 35 5 pathway pathway NN cord-270467-es6dnx36 35 6 is be VBZ cord-270467-es6dnx36 35 7 involved involve VBN cord-270467-es6dnx36 35 8 in in IN cord-270467-es6dnx36 35 9 other other JJ cord-270467-es6dnx36 35 10 cases case NNS cord-270467-es6dnx36 35 11 of of IN cord-270467-es6dnx36 35 12 virus virus NN cord-270467-es6dnx36 35 13 infection infection NN cord-270467-es6dnx36 35 14 ( ( -LRB- cord-270467-es6dnx36 35 15 9 9 CD cord-270467-es6dnx36 35 16 ) ) -RRB- cord-270467-es6dnx36 35 17 . . . cord-270467-es6dnx36 36 1 Viruses virus NNS cord-270467-es6dnx36 36 2 require require VBP cord-270467-es6dnx36 36 3 not not RB cord-270467-es6dnx36 36 4 only only RB cord-270467-es6dnx36 36 5 membranes membrane NNS cord-270467-es6dnx36 36 6 on on IN cord-270467-es6dnx36 36 7 which which WDT cord-270467-es6dnx36 36 8 to to TO cord-270467-es6dnx36 36 9 replicate replicate VB cord-270467-es6dnx36 36 10 but but CC cord-270467-es6dnx36 36 11 also also RB cord-270467-es6dnx36 36 12 specific specific JJ cord-270467-es6dnx36 36 13 lipids lipid NNS cord-270467-es6dnx36 36 14 ; ; : cord-270467-es6dnx36 36 15 lipotoxicity lipotoxicity NN cord-270467-es6dnx36 36 16 in in IN cord-270467-es6dnx36 36 17 obesity obesity NN cord-270467-es6dnx36 36 18 might may MD cord-270467-es6dnx36 36 19 answer answer VB cord-270467-es6dnx36 36 20 to to IN cord-270467-es6dnx36 36 21 these these DT cord-270467-es6dnx36 36 22 requirements requirement NNS cord-270467-es6dnx36 36 23 . . . cord-270467-es6dnx36 37 1 IR IR NNP cord-270467-es6dnx36 37 2 is be VBZ cord-270467-es6dnx36 37 3 the the DT cord-270467-es6dnx36 37 4 molecular molecular JJ cord-270467-es6dnx36 37 5 feature feature NN cord-270467-es6dnx36 37 6 of of IN cord-270467-es6dnx36 37 7 Metabolic Metabolic NNP cord-270467-es6dnx36 37 8 Syndrome Syndrome NNP cord-270467-es6dnx36 37 9 ( ( -LRB- cord-270467-es6dnx36 37 10 MES MES NNP cord-270467-es6dnx36 37 11 ) ) -RRB- cord-270467-es6dnx36 37 12 , , , cord-270467-es6dnx36 37 13 a a DT cord-270467-es6dnx36 37 14 cluster cluster NN cord-270467-es6dnx36 37 15 of of IN cord-270467-es6dnx36 37 16 metabolic metabolic JJ cord-270467-es6dnx36 37 17 risk risk NN cord-270467-es6dnx36 37 18 factors factor NNS cord-270467-es6dnx36 37 19 for for IN cord-270467-es6dnx36 37 20 cardiovascular cardiovascular JJ cord-270467-es6dnx36 37 21 disease disease NN cord-270467-es6dnx36 37 22 As as IN cord-270467-es6dnx36 37 23 an an DT cord-270467-es6dnx36 37 24 analogy analogy NN cord-270467-es6dnx36 37 25 , , , cord-270467-es6dnx36 37 26 the the DT cord-270467-es6dnx36 37 27 global global JJ cord-270467-es6dnx36 37 28 risk risk NN cord-270467-es6dnx36 37 29 would would MD cord-270467-es6dnx36 37 30 not not RB cord-270467-es6dnx36 37 31 depend depend VB cord-270467-es6dnx36 37 32 on on IN cord-270467-es6dnx36 37 33 the the DT cord-270467-es6dnx36 37 34 sum sum NN cord-270467-es6dnx36 37 35 of of IN cord-270467-es6dnx36 37 36 every every DT cord-270467-es6dnx36 37 37 single single JJ cord-270467-es6dnx36 37 38 factor factor NN cord-270467-es6dnx36 37 39 , , , cord-270467-es6dnx36 37 40 but but CC cord-270467-es6dnx36 37 41 is be VBZ cord-270467-es6dnx36 37 42 likely likely JJ cord-270467-es6dnx36 37 43 to to TO cord-270467-es6dnx36 37 44 be be VB cord-270467-es6dnx36 37 45 affected affect VBN cord-270467-es6dnx36 37 46 by by IN cord-270467-es6dnx36 37 47 the the DT cord-270467-es6dnx36 37 48 exponential exponential JJ cord-270467-es6dnx36 37 49 and and CC cord-270467-es6dnx36 37 50 multiplicative multiplicative JJ cord-270467-es6dnx36 37 51 elements element NNS cord-270467-es6dnx36 37 52 ( ( -LRB- cord-270467-es6dnx36 37 53 3 3 CD cord-270467-es6dnx36 37 54 ) ) -RRB- cord-270467-es6dnx36 37 55 . . . cord-270467-es6dnx36 38 1 Therefore therefore RB cord-270467-es6dnx36 38 2 , , , cord-270467-es6dnx36 38 3 to to TO cord-270467-es6dnx36 38 4 build build VB cord-270467-es6dnx36 38 5 an an DT cord-270467-es6dnx36 38 6 integrated integrated JJ cord-270467-es6dnx36 38 7 pathogenetic pathogenetic JJ cord-270467-es6dnx36 38 8 model model NN cord-270467-es6dnx36 38 9 to to TO cord-270467-es6dnx36 38 10 be be VB cord-270467-es6dnx36 38 11 as as RB cord-270467-es6dnx36 38 12 extensive extensive JJ cord-270467-es6dnx36 38 13 as as IN cord-270467-es6dnx36 38 14 possible possible JJ cord-270467-es6dnx36 38 15 is be VBZ cord-270467-es6dnx36 38 16 advisable advisable JJ cord-270467-es6dnx36 38 17 . . . cord-270467-es6dnx36 39 1 IR IR NNP cord-270467-es6dnx36 39 2 was be VBD cord-270467-es6dnx36 39 3 found find VBN cord-270467-es6dnx36 39 4 in in IN cord-270467-es6dnx36 39 5 patients patient NNS cord-270467-es6dnx36 39 6 with with IN cord-270467-es6dnx36 39 7 hepatitis hepatitis NN cord-270467-es6dnx36 39 8 C C NNP cord-270467-es6dnx36 39 9 virus virus NN cord-270467-es6dnx36 39 10 ( ( -LRB- cord-270467-es6dnx36 39 11 HCV HCV NNP cord-270467-es6dnx36 39 12 ) ) -RRB- cord-270467-es6dnx36 39 13 infection infection NN cord-270467-es6dnx36 39 14 and and CC cord-270467-es6dnx36 39 15 often often RB cord-270467-es6dnx36 39 16 leads lead VBZ cord-270467-es6dnx36 39 17 to to IN cord-270467-es6dnx36 39 18 the the DT cord-270467-es6dnx36 39 19 development development NN cord-270467-es6dnx36 39 20 of of IN cord-270467-es6dnx36 39 21 type type NN cord-270467-es6dnx36 39 22 II ii CD cord-270467-es6dnx36 39 23 diabetes diabetes NN cord-270467-es6dnx36 39 24 ( ( -LRB- cord-270467-es6dnx36 39 25 10 10 CD cord-270467-es6dnx36 39 26 ) ) -RRB- cord-270467-es6dnx36 39 27 . . . cord-270467-es6dnx36 40 1 As as IN cord-270467-es6dnx36 40 2 role role NN cord-270467-es6dnx36 40 3 of of IN cord-270467-es6dnx36 40 4 MES MES NNP cord-270467-es6dnx36 40 5 in in IN cord-270467-es6dnx36 40 6 COVID-19 COVID-19 NNP cord-270467-es6dnx36 40 7 is be VBZ cord-270467-es6dnx36 40 8 not not RB cord-270467-es6dnx36 40 9 clear clear JJ cord-270467-es6dnx36 40 10 , , , cord-270467-es6dnx36 40 11 patients patient NNS cord-270467-es6dnx36 40 12 need need VBP cord-270467-es6dnx36 40 13 an an DT cord-270467-es6dnx36 40 14 accurate accurate JJ cord-270467-es6dnx36 40 15 metabolic metabolic JJ cord-270467-es6dnx36 40 16 assessment assessment NN cord-270467-es6dnx36 40 17 . . . cord-270467-es6dnx36 41 1 Finucane Finucane NNP cord-270467-es6dnx36 41 2 and and CC cord-270467-es6dnx36 41 3 Davenport Davenport NNP cord-270467-es6dnx36 41 4 concluded conclude VBD cord-270467-es6dnx36 41 5 with with IN cord-270467-es6dnx36 41 6 suggestions suggestion NNS cord-270467-es6dnx36 41 7 for for IN cord-270467-es6dnx36 41 8 clinical clinical JJ cord-270467-es6dnx36 41 9 implications implication NNS cord-270467-es6dnx36 41 10 for for IN cord-270467-es6dnx36 41 11 studying study VBG cord-270467-es6dnx36 41 12 insulin insulin NN cord-270467-es6dnx36 41 13 action action NN cord-270467-es6dnx36 41 14 in in IN cord-270467-es6dnx36 41 15 relation relation NN cord-270467-es6dnx36 41 16 to to IN cord-270467-es6dnx36 41 17 COVID-19 covid-19 JJ cord-270467-es6dnx36 41 18 severity severity NN cord-270467-es6dnx36 41 19 . . . cord-270467-es6dnx36 42 1 Unfortunately unfortunately RB cord-270467-es6dnx36 42 2 , , , cord-270467-es6dnx36 42 3 in in IN cord-270467-es6dnx36 42 4 the the DT cord-270467-es6dnx36 42 5 initial initial JJ cord-270467-es6dnx36 42 6 studies study NNS cord-270467-es6dnx36 42 7 of of IN cord-270467-es6dnx36 42 8 COVID-19 COVID-19 NNP cord-270467-es6dnx36 42 9 , , , cord-270467-es6dnx36 42 10 no no DT cord-270467-es6dnx36 42 11 data datum NNS cord-270467-es6dnx36 42 12 about about IN cord-270467-es6dnx36 42 13 insulin insulin NN cord-270467-es6dnx36 42 14 determination determination NN cord-270467-es6dnx36 42 15 , , , cord-270467-es6dnx36 42 16 BMI BMI NNP cord-270467-es6dnx36 42 17 , , , cord-270467-es6dnx36 42 18 or or CC cord-270467-es6dnx36 42 19 other other JJ cord-270467-es6dnx36 42 20 systematic systematic JJ cord-270467-es6dnx36 42 21 metabolic metabolic JJ cord-270467-es6dnx36 42 22 determinations determination NNS cord-270467-es6dnx36 42 23 are be VBP cord-270467-es6dnx36 42 24 available available JJ cord-270467-es6dnx36 42 25 . . . cord-270467-es6dnx36 43 1 Currently currently RB cord-270467-es6dnx36 43 2 , , , cord-270467-es6dnx36 43 3 regarding regard VBG cord-270467-es6dnx36 43 4 the the DT cord-270467-es6dnx36 43 5 application application NN cord-270467-es6dnx36 43 6 in in IN cord-270467-es6dnx36 43 7 routine routine JJ cord-270467-es6dnx36 43 8 clinical clinical JJ cord-270467-es6dnx36 43 9 practice practice NN cord-270467-es6dnx36 43 10 , , , cord-270467-es6dnx36 43 11 concerns concern NNS cord-270467-es6dnx36 43 12 arise arise VBP cord-270467-es6dnx36 43 13 about about IN cord-270467-es6dnx36 43 14 the the DT cord-270467-es6dnx36 43 15 feasibility feasibility NN cord-270467-es6dnx36 43 16 of of IN cord-270467-es6dnx36 43 17 measuring measure VBG cord-270467-es6dnx36 43 18 IR IR NNP cord-270467-es6dnx36 43 19 in in IN cord-270467-es6dnx36 43 20 acutely acutely RB cord-270467-es6dnx36 43 21 ill ill JJ cord-270467-es6dnx36 43 22 patients patient NNS cord-270467-es6dnx36 43 23 . . . cord-270467-es6dnx36 44 1 Furthermore furthermore RB cord-270467-es6dnx36 44 2 , , , cord-270467-es6dnx36 44 3 it -PRON- PRP cord-270467-es6dnx36 44 4 is be VBZ cord-270467-es6dnx36 44 5 arguable arguable JJ cord-270467-es6dnx36 44 6 how how WRB cord-270467-es6dnx36 44 7 valid valid JJ cord-270467-es6dnx36 44 8 the the DT cord-270467-es6dnx36 44 9 measure measure NN cord-270467-es6dnx36 44 10 could could MD cord-270467-es6dnx36 44 11 be be VB cord-270467-es6dnx36 44 12 in in IN cord-270467-es6dnx36 44 13 people people NNS cord-270467-es6dnx36 44 14 who who WP cord-270467-es6dnx36 44 15 fell fall VBD cord-270467-es6dnx36 44 16 sick sick JJ cord-270467-es6dnx36 44 17 and and CC cord-270467-es6dnx36 44 18 then then RB cord-270467-es6dnx36 44 19 fasted fast VBD cord-270467-es6dnx36 44 20 for for IN cord-270467-es6dnx36 44 21 several several JJ cord-270467-es6dnx36 44 22 days day NNS cord-270467-es6dnx36 44 23 before before IN cord-270467-es6dnx36 44 24 admission admission NN cord-270467-es6dnx36 44 25 to to IN cord-270467-es6dnx36 44 26 the the DT cord-270467-es6dnx36 44 27 hospital hospital NN cord-270467-es6dnx36 44 28 . . . cord-270467-es6dnx36 45 1 Therefore therefore RB cord-270467-es6dnx36 45 2 , , , cord-270467-es6dnx36 45 3 a a DT cord-270467-es6dnx36 45 4 noninvasive noninvasive JJ cord-270467-es6dnx36 45 5 way way NN cord-270467-es6dnx36 45 6 to to TO cord-270467-es6dnx36 45 7 assess assess VB cord-270467-es6dnx36 45 8 the the DT cord-270467-es6dnx36 45 9 long long JJ cord-270467-es6dnx36 45 10 - - HYPH cord-270467-es6dnx36 45 11 term term NN cord-270467-es6dnx36 45 12 consequences consequence NNS cord-270467-es6dnx36 45 13 of of IN cord-270467-es6dnx36 45 14 insulin insulin NN cord-270467-es6dnx36 45 15 and and CC cord-270467-es6dnx36 45 16 lipid lipid NN cord-270467-es6dnx36 45 17 impairment impairment NN cord-270467-es6dnx36 45 18 could could MD cord-270467-es6dnx36 45 19 be be VB cord-270467-es6dnx36 45 20 done do VBN cord-270467-es6dnx36 45 21 through through IN cord-270467-es6dnx36 45 22 the the DT cord-270467-es6dnx36 45 23 screening screening NN cord-270467-es6dnx36 45 24 of of IN cord-270467-es6dnx36 45 25 nonalcoholic nonalcoholic JJ cord-270467-es6dnx36 45 26 fatty fatty JJ cord-270467-es6dnx36 45 27 liver liver NN cord-270467-es6dnx36 45 28 disease disease NN cord-270467-es6dnx36 45 29 ( ( -LRB- cord-270467-es6dnx36 45 30 NAFLD NAFLD NNP cord-270467-es6dnx36 45 31 , , , cord-270467-es6dnx36 45 32 the the DT cord-270467-es6dnx36 45 33 hepatic hepatic JJ cord-270467-es6dnx36 45 34 manifestation manifestation NN cord-270467-es6dnx36 45 35 of of IN cord-270467-es6dnx36 45 36 MES MES NNP cord-270467-es6dnx36 45 37 and and CC cord-270467-es6dnx36 45 38 IR IR NNP cord-270467-es6dnx36 45 39 ) ) -RRB- cord-270467-es6dnx36 45 40 , , , cord-270467-es6dnx36 45 41 i.e. i.e. FW cord-270467-es6dnx36 45 42 , , , cord-270467-es6dnx36 45 43 through through IN cord-270467-es6dnx36 45 44 the the DT cord-270467-es6dnx36 45 45 use use NN cord-270467-es6dnx36 45 46 of of IN cord-270467-es6dnx36 45 47 Fibroscan Fibroscan NNP cord-270467-es6dnx36 45 48 ( ( -LRB- cord-270467-es6dnx36 45 49 11 11 CD cord-270467-es6dnx36 45 50 ) ) -RRB- cord-270467-es6dnx36 45 51 . . . cord-270467-es6dnx36 46 1 These these DT cord-270467-es6dnx36 46 2 preliminary preliminary JJ cord-270467-es6dnx36 46 3 observations observation NNS cord-270467-es6dnx36 46 4 are be VBP cord-270467-es6dnx36 46 5 highlighting highlight VBG cord-270467-es6dnx36 46 6 the the DT cord-270467-es6dnx36 46 7 need need NN cord-270467-es6dnx36 46 8 to to TO cord-270467-es6dnx36 46 9 intensively intensively RB cord-270467-es6dnx36 46 10 investigate investigate VB cord-270467-es6dnx36 46 11 IR IR NNP cord-270467-es6dnx36 46 12 and and CC cord-270467-es6dnx36 46 13 other other JJ cord-270467-es6dnx36 46 14 components component NNS cord-270467-es6dnx36 46 15 of of IN cord-270467-es6dnx36 46 16 MES MES NNP cord-270467-es6dnx36 46 17 in in IN cord-270467-es6dnx36 46 18 COVID-19 covid-19 JJ cord-270467-es6dnx36 46 19 pathogenesis pathogenesis NN cord-270467-es6dnx36 46 20 . . . cord-270467-es6dnx36 47 1 For for IN cord-270467-es6dnx36 47 2 this this DT cord-270467-es6dnx36 47 3 purpose purpose NN cord-270467-es6dnx36 47 4 , , , cord-270467-es6dnx36 47 5 advanced advanced JJ cord-270467-es6dnx36 47 6 digital digital JJ cord-270467-es6dnx36 47 7 solutions solution NNS cord-270467-es6dnx36 47 8 ( ( -LRB- cord-270467-es6dnx36 47 9 big big JJ cord-270467-es6dnx36 47 10 data datum NNS cord-270467-es6dnx36 47 11 , , , cord-270467-es6dnx36 47 12 artificial artificial JJ cord-270467-es6dnx36 47 13 intelligence intelligence NN cord-270467-es6dnx36 47 14 , , , cord-270467-es6dnx36 47 15 machine machine NN cord-270467-es6dnx36 47 16 learning learning NN cord-270467-es6dnx36 47 17 ) ) -RRB- cord-270467-es6dnx36 47 18 for for IN cord-270467-es6dnx36 47 19 the the DT cord-270467-es6dnx36 47 20 development development NN cord-270467-es6dnx36 47 21 of of IN cord-270467-es6dnx36 47 22 sophisticated sophisticated JJ cord-270467-es6dnx36 47 23 real real JJ cord-270467-es6dnx36 47 24 - - HYPH cord-270467-es6dnx36 47 25 world world NN cord-270467-es6dnx36 47 26 based base VBN cord-270467-es6dnx36 47 27 algorithms algorithm NNS cord-270467-es6dnx36 47 28 must must MD cord-270467-es6dnx36 47 29 be be VB cord-270467-es6dnx36 47 30 promoted promote VBN cord-270467-es6dnx36 47 31 . . . cord-270467-es6dnx36 48 1 The the DT cord-270467-es6dnx36 48 2 author author NN cord-270467-es6dnx36 48 3 confirms confirm VBZ cord-270467-es6dnx36 48 4 being be VBG cord-270467-es6dnx36 48 5 the the DT cord-270467-es6dnx36 48 6 sole sole JJ cord-270467-es6dnx36 48 7 contributor contributor NN cord-270467-es6dnx36 48 8 of of IN cord-270467-es6dnx36 48 9 this this DT cord-270467-es6dnx36 48 10 work work NN cord-270467-es6dnx36 48 11 and and CC cord-270467-es6dnx36 48 12 has have VBZ cord-270467-es6dnx36 48 13 approved approve VBN cord-270467-es6dnx36 48 14 it -PRON- PRP cord-270467-es6dnx36 48 15 for for IN cord-270467-es6dnx36 48 16 publication publication NN cord-270467-es6dnx36 48 17 . . . cord-270467-es6dnx36 49 1 Coronavirus Coronavirus NNP cord-270467-es6dnx36 49 2 and and CC cord-270467-es6dnx36 49 3 obesity obesity NN cord-270467-es6dnx36 49 4 : : : cord-270467-es6dnx36 49 5 could could MD cord-270467-es6dnx36 49 6 insulin insulin VB cord-270467-es6dnx36 49 7 resistance resistance NN cord-270467-es6dnx36 49 8 mediate mediate VB cord-270467-es6dnx36 49 9 the the DT cord-270467-es6dnx36 49 10 severity severity NN cord-270467-es6dnx36 49 11 of of IN cord-270467-es6dnx36 49 12 COVID-19 covid-19 JJ cord-270467-es6dnx36 49 13 infection infection NN cord-270467-es6dnx36 49 14 ? ? . cord-270467-es6dnx36 50 1 Front Front NNP cord-270467-es6dnx36 50 2 Public Public NNP cord-270467-es6dnx36 50 3 Health Health NNP cord-270467-es6dnx36 50 4 Prevalence prevalence NN cord-270467-es6dnx36 50 5 of of IN cord-270467-es6dnx36 50 6 comorbidities comorbiditie NNS cord-270467-es6dnx36 50 7 and and CC cord-270467-es6dnx36 50 8 its -PRON- PRP$ cord-270467-es6dnx36 50 9 effects effect NNS cord-270467-es6dnx36 50 10 in in IN cord-270467-es6dnx36 50 11 coronavirus coronavirus NN cord-270467-es6dnx36 50 12 disease disease NN cord-270467-es6dnx36 50 13 2019 2019 CD cord-270467-es6dnx36 50 14 patients patient NNS cord-270467-es6dnx36 50 15 : : : cord-270467-es6dnx36 50 16 a a DT cord-270467-es6dnx36 50 17 systematic systematic JJ cord-270467-es6dnx36 50 18 review review NN cord-270467-es6dnx36 50 19 and and CC cord-270467-es6dnx36 50 20 meta meta NNP cord-270467-es6dnx36 50 21 - - HYPH cord-270467-es6dnx36 50 22 analysis analysis NN cord-270467-es6dnx36 50 23 Is be VBZ cord-270467-es6dnx36 50 24 insulin insulin NN cord-270467-es6dnx36 50 25 resistant resistant JJ cord-270467-es6dnx36 50 26 brain brain NN cord-270467-es6dnx36 50 27 state state NN cord-270467-es6dnx36 51 1 a a DT cord-270467-es6dnx36 51 2 central central JJ cord-270467-es6dnx36 51 3 feature feature NN cord-270467-es6dnx36 51 4 of of IN cord-270467-es6dnx36 51 5 the the DT cord-270467-es6dnx36 51 6 metabolic metabolic JJ cord-270467-es6dnx36 51 7 - - HYPH cord-270467-es6dnx36 51 8 cognitive cognitive JJ cord-270467-es6dnx36 51 9 syndrome syndrome NN cord-270467-es6dnx36 51 10 ? ? . cord-270467-es6dnx36 52 1 Metabolic metabolic JJ cord-270467-es6dnx36 52 2 - - HYPH cord-270467-es6dnx36 52 3 cognitive cognitive JJ cord-270467-es6dnx36 52 4 syndrome syndrome NN cord-270467-es6dnx36 52 5 : : : cord-270467-es6dnx36 52 6 a a DT cord-270467-es6dnx36 52 7 cross cross NN cord-270467-es6dnx36 52 8 - - NN cord-270467-es6dnx36 52 9 talk talk NN cord-270467-es6dnx36 52 10 between between IN cord-270467-es6dnx36 52 11 metabolic metabolic JJ cord-270467-es6dnx36 52 12 syndrome syndrome NN cord-270467-es6dnx36 52 13 and and CC cord-270467-es6dnx36 52 14 Alzheimer Alzheimer NNP cord-270467-es6dnx36 52 15 's 's POS cord-270467-es6dnx36 52 16 disease disease NN cord-270467-es6dnx36 53 1 The the DT cord-270467-es6dnx36 53 2 role role NN cord-270467-es6dnx36 53 3 of of IN cord-270467-es6dnx36 53 4 leptin leptin NN cord-270467-es6dnx36 53 5 in in IN cord-270467-es6dnx36 53 6 the the DT cord-270467-es6dnx36 53 7 control control NN cord-270467-es6dnx36 53 8 of of IN cord-270467-es6dnx36 53 9 insulin insulin NN cord-270467-es6dnx36 53 10 - - HYPH cord-270467-es6dnx36 53 11 glucose glucose NN cord-270467-es6dnx36 53 12 axis axis NN cord-270467-es6dnx36 53 13 Obesity obesity NN cord-270467-es6dnx36 53 14 and and CC cord-270467-es6dnx36 53 15 insulin insulin NN cord-270467-es6dnx36 53 16 resistance resistance NN cord-270467-es6dnx36 53 17 Membrane membrane NN cord-270467-es6dnx36 53 18 - - HYPH cord-270467-es6dnx36 53 19 anchored anchor VBN cord-270467-es6dnx36 53 20 serine serine NN cord-270467-es6dnx36 53 21 proteases protease NNS cord-270467-es6dnx36 53 22 in in IN cord-270467-es6dnx36 53 23 health health NN cord-270467-es6dnx36 53 24 and and CC cord-270467-es6dnx36 53 25 disease disease NN cord-270467-es6dnx36 53 26 progress progress NN cord-270467-es6dnx36 53 27 Host host NN cord-270467-es6dnx36 53 28 lipids lipid NNS cord-270467-es6dnx36 53 29 in in IN cord-270467-es6dnx36 53 30 positive positive JJ cord-270467-es6dnx36 53 31 - - HYPH cord-270467-es6dnx36 53 32 strand strand NN cord-270467-es6dnx36 53 33 RNA RNA NNP cord-270467-es6dnx36 53 34 virus virus NN cord-270467-es6dnx36 53 35 genome genome NN cord-270467-es6dnx36 53 36 replication replication NN cord-270467-es6dnx36 53 37 Role role NN cord-270467-es6dnx36 53 38 of of IN cord-270467-es6dnx36 53 39 SREBPs srebp NNS cord-270467-es6dnx36 53 40 in in IN cord-270467-es6dnx36 53 41 liver liver NN cord-270467-es6dnx36 53 42 diseases disease NNS cord-270467-es6dnx36 53 43 : : : cord-270467-es6dnx36 53 44 a a DT cord-270467-es6dnx36 53 45 minireview minireview NNP cord-270467-es6dnx36 53 46 Hepatitis Hepatitis NNP cord-270467-es6dnx36 53 47 C C NNP cord-270467-es6dnx36 53 48 virus virus NN cord-270467-es6dnx36 53 49 infection infection NN cord-270467-es6dnx36 53 50 and and CC cord-270467-es6dnx36 53 51 insulin insulin NN cord-270467-es6dnx36 53 52 resistance resistance NN cord-270467-es6dnx36 53 53 Non non JJ cord-270467-es6dnx36 53 54 - - JJ cord-270467-es6dnx36 53 55 alcoholic alcoholic JJ cord-270467-es6dnx36 53 56 fatty fatty JJ cord-270467-es6dnx36 53 57 liver liver NN cord-270467-es6dnx36 53 58 diseases disease NNS cord-270467-es6dnx36 53 59 in in IN cord-270467-es6dnx36 53 60 patients patient NNS cord-270467-es6dnx36 53 61 with with IN cord-270467-es6dnx36 53 62 COVID-19 COVID-19 NNP cord-270467-es6dnx36 53 63 : : : cord-270467-es6dnx36 53 64 a a DT cord-270467-es6dnx36 53 65 retrospective retrospective JJ cord-270467-es6dnx36 53 66 study study NN cord-270467-es6dnx36 53 67 I -PRON- PRP cord-270467-es6dnx36 53 68 thank thank VBP cord-270467-es6dnx36 53 69 you -PRON- PRP cord-270467-es6dnx36 53 70 all all PDT cord-270467-es6dnx36 53 71 my -PRON- PRP$ cord-270467-es6dnx36 53 72 colleagues colleague NNS cord-270467-es6dnx36 53 73 and and CC cord-270467-es6dnx36 53 74 in in IN cord-270467-es6dnx36 53 75 particular particular JJ cord-270467-es6dnx36 53 76 Dr. Dr. NNP cord-270467-es6dnx36 53 77 Mariangela Mariangela NNP cord-270467-es6dnx36 53 78 Brunetti Brunetti NNP cord-270467-es6dnx36 53 79 who who WP cord-270467-es6dnx36 53 80 got get VBD cord-270467-es6dnx36 53 81 sick sick JJ cord-270467-es6dnx36 53 82 by by IN cord-270467-es6dnx36 53 83 working work VBG cord-270467-es6dnx36 53 84 all all DT cord-270467-es6dnx36 53 85 day day NN cord-270467-es6dnx36 53 86 long long RB cord-270467-es6dnx36 53 87 in in IN cord-270467-es6dnx36 53 88 COVID COVID NNP cord-270467-es6dnx36 53 89 area area NN cord-270467-es6dnx36 53 90 and and CC cord-270467-es6dnx36 53 91 Dr. Dr. NNP cord-270467-es6dnx36 53 92 Virginia Virginia NNP cord-270467-es6dnx36 53 93 Dolcinia Dolcinia NNP cord-270467-es6dnx36 53 94 who who WP cord-270467-es6dnx36 53 95 gave give VBD cord-270467-es6dnx36 53 96 me -PRON- PRP cord-270467-es6dnx36 53 97 the the DT cord-270467-es6dnx36 53 98 timely timely RB cord-270467-es6dnx36 53 99 psychological psychological JJ cord-270467-es6dnx36 53 100 and and CC cord-270467-es6dnx36 53 101 material material JJ cord-270467-es6dnx36 53 102 support support NN cord-270467-es6dnx36 53 103 to to TO cord-270467-es6dnx36 53 104 keep keep VB cord-270467-es6dnx36 53 105 my -PRON- PRP$ cord-270467-es6dnx36 53 106 professional professional JJ cord-270467-es6dnx36 53 107 career career NN cord-270467-es6dnx36 53 108 ongoing ongoe VBG cord-270467-es6dnx36 53 109 despite despite IN cord-270467-es6dnx36 53 110 the the DT cord-270467-es6dnx36 53 111 terrible terrible JJ cord-270467-es6dnx36 53 112 moments moment NNS cord-270467-es6dnx36 53 113 everyone everyone NN cord-270467-es6dnx36 53 114 experienced experience VBD cord-270467-es6dnx36 53 115 as as RB cord-270467-es6dnx36 53 116 well well RB cord-270467-es6dnx36 53 117 . . . cord-270467-es6dnx36 54 1 The the DT cord-270467-es6dnx36 54 2 author author NN cord-270467-es6dnx36 54 3 declares declare VBZ cord-270467-es6dnx36 54 4 that that IN cord-270467-es6dnx36 54 5 the the DT cord-270467-es6dnx36 54 6 research research NN cord-270467-es6dnx36 54 7 was be VBD cord-270467-es6dnx36 54 8 conducted conduct VBN cord-270467-es6dnx36 54 9 in in IN cord-270467-es6dnx36 54 10 the the DT cord-270467-es6dnx36 54 11 absence absence NN cord-270467-es6dnx36 54 12 of of IN cord-270467-es6dnx36 54 13 any any DT cord-270467-es6dnx36 54 14 commercial commercial JJ cord-270467-es6dnx36 54 15 or or CC cord-270467-es6dnx36 54 16 financial financial JJ cord-270467-es6dnx36 54 17 relationships relationship NNS cord-270467-es6dnx36 54 18 that that WDT cord-270467-es6dnx36 54 19 could could MD cord-270467-es6dnx36 54 20 be be VB cord-270467-es6dnx36 54 21 construed construe VBN cord-270467-es6dnx36 54 22 as as IN cord-270467-es6dnx36 54 23 a a DT cord-270467-es6dnx36 54 24 potential potential JJ cord-270467-es6dnx36 54 25 conflict conflict NN cord-270467-es6dnx36 54 26 of of IN cord-270467-es6dnx36 54 27 interest interest NN cord-270467-es6dnx36 54 28 . . . cord-270467-es6dnx36 55 1 Copyright copyright NN cord-270467-es6dnx36 55 2 © © NNP cord-270467-es6dnx36 55 3 2020 2020 CD cord-270467-es6dnx36 55 4 Frisardi Frisardi NNP cord-270467-es6dnx36 55 5 . . . cord-270467-es6dnx36 56 1 This this DT cord-270467-es6dnx36 56 2 is be VBZ cord-270467-es6dnx36 56 3 an an DT cord-270467-es6dnx36 56 4 open open JJ cord-270467-es6dnx36 56 5 - - HYPH cord-270467-es6dnx36 56 6 access access NN cord-270467-es6dnx36 56 7 article article NN cord-270467-es6dnx36 56 8 distributed distribute VBN cord-270467-es6dnx36 56 9 under under IN cord-270467-es6dnx36 56 10 the the DT cord-270467-es6dnx36 56 11 terms term NNS cord-270467-es6dnx36 56 12 of of IN cord-270467-es6dnx36 56 13 the the DT cord-270467-es6dnx36 56 14 Creative Creative NNP cord-270467-es6dnx36 56 15 Commons Commons NNP cord-270467-es6dnx36 56 16 Attribution Attribution NNP cord-270467-es6dnx36 56 17 License License NNP cord-270467-es6dnx36 56 18 ( ( -LRB- cord-270467-es6dnx36 56 19 CC CC NNP cord-270467-es6dnx36 56 20 BY BY NNP cord-270467-es6dnx36 56 21 ) ) -RRB- cord-270467-es6dnx36 56 22 . . . cord-270467-es6dnx36 57 1 The the DT cord-270467-es6dnx36 57 2 use use NN cord-270467-es6dnx36 57 3 , , , cord-270467-es6dnx36 57 4 distribution distribution NN cord-270467-es6dnx36 57 5 or or CC cord-270467-es6dnx36 57 6 reproduction reproduction NN cord-270467-es6dnx36 57 7 in in IN cord-270467-es6dnx36 57 8 other other JJ cord-270467-es6dnx36 57 9 forums forum NNS cord-270467-es6dnx36 57 10 is be VBZ cord-270467-es6dnx36 57 11 permitted permit VBN cord-270467-es6dnx36 57 12 , , , cord-270467-es6dnx36 57 13 provided provide VBD cord-270467-es6dnx36 57 14 the the DT cord-270467-es6dnx36 57 15 original original JJ cord-270467-es6dnx36 57 16 author(s author(s NNP cord-270467-es6dnx36 57 17 ) ) -RRB- cord-270467-es6dnx36 57 18 and and CC cord-270467-es6dnx36 57 19 the the DT cord-270467-es6dnx36 57 20 copyright copyright NN cord-270467-es6dnx36 57 21 owner(s owner(s NNP cord-270467-es6dnx36 57 22 ) ) -RRB- cord-270467-es6dnx36 57 23 are be VBP cord-270467-es6dnx36 57 24 credited credit VBN cord-270467-es6dnx36 57 25 and and CC cord-270467-es6dnx36 57 26 that that IN cord-270467-es6dnx36 57 27 the the DT cord-270467-es6dnx36 57 28 original original JJ cord-270467-es6dnx36 57 29 publication publication NN cord-270467-es6dnx36 57 30 in in IN cord-270467-es6dnx36 57 31 this this DT cord-270467-es6dnx36 57 32 journal journal NN cord-270467-es6dnx36 57 33 is be VBZ cord-270467-es6dnx36 57 34 cited cite VBN cord-270467-es6dnx36 57 35 , , , cord-270467-es6dnx36 57 36 in in IN cord-270467-es6dnx36 57 37 accordance accordance NN cord-270467-es6dnx36 57 38 with with IN cord-270467-es6dnx36 57 39 accepted accepted JJ cord-270467-es6dnx36 57 40 academic academic JJ cord-270467-es6dnx36 57 41 practice practice NN cord-270467-es6dnx36 57 42 . . . cord-270467-es6dnx36 58 1 No no DT cord-270467-es6dnx36 58 2 use use NN cord-270467-es6dnx36 58 3 , , , cord-270467-es6dnx36 58 4 distribution distribution NN cord-270467-es6dnx36 58 5 or or CC cord-270467-es6dnx36 58 6 reproduction reproduction NN cord-270467-es6dnx36 58 7 is be VBZ cord-270467-es6dnx36 58 8 permitted permit VBN cord-270467-es6dnx36 58 9 which which WDT cord-270467-es6dnx36 58 10 does do VBZ cord-270467-es6dnx36 58 11 not not RB cord-270467-es6dnx36 58 12 comply comply VB cord-270467-es6dnx36 58 13 with with IN cord-270467-es6dnx36 58 14 these these DT cord-270467-es6dnx36 58 15 terms term NNS cord-270467-es6dnx36 58 16 . . .