id author title date pages extension mime words sentences flesch summary cache txt cord-279836-lyvvtwvg Li, Huiping Molecular detection and genomic characteristics of bovine kobuvirus from dairy calves in China 2019-06-24 .txt text/plain 2277 111 60 In this study, 96 diarrheic and 77 non-diarrheic fecal samples from dairy calves were collected from 14 dairy farms in 4 provinces to investigate the molecular prevalence and genomic characteristics of Bovine Kobuvirus (BKoV) in China. Interestingly, three potential novel VP1 lineages were identified from 15 complete VP1 sequences, and a unique triple nucleotide insertion which can result in an aa insertion, was first observed in the 11/12 VP0 fragments with 660 bp long in this study, compared with known BKoV VP0 sequences. Interestingly, phylogenetic tree based on aa sequences of these genomes showed that CHZ/CHINA was clustered into an independent branch, suggesting the strain may represent a novel BKoV strain. Further phylogenetic analysis based on genomic sequences revealed that CHZ/CHINA clusters on an independent branch, with the three VP0, VP3, VP1 protein aa sequences generating the same result (Fig. 3) , showing that CHZ/CHINA displays a larger genetic distance from the other three genomes and indicating that CHZ/CHINA may represent a novel BKoV strain. ./cache/cord-279836-lyvvtwvg.txt ./txt/cord-279836-lyvvtwvg.txt