id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-293588-7pflfznh	Zang, Minghui	Analysis of the codon usage of the ORF2 gene of feline calicivirus	2017-06-16		.txt	text/plain	3064	162	58	Furthermore, there was a significant correlation between the ENC values and the nucleotide compositions (p b 0.01), which indicates that mutational bias influences the synonymous codon usage pattern of the ORF2 gene of FCV. We found a correlation between the Aroma values and U3 s, G3 s and GC3s (p b 0.05), confirming that natural selection influences the codon usage bias of the FCV ORF2 gene. Thus, natural selection plays a major role in shaping the codon usage bias of ORF2 gene of FCV compared to mutational pressure. Here, we used ENC-Plots (Fig. 1) and PCA (Fig. 3) analysis according to the geographical distribution to investigate the major factors shaping the codon usage bias of the FCV ORF2 gene . Furthermore, analysis of the relationships between nucleotide composition and the codon contents at the third base positions suggested that mutation pressure is one of the factors in shaping the codon usage of FCV ORF2.	./cache/cord-293588-7pflfznh.txt	./txt/cord-293588-7pflfznh.txt