id author title date pages extension mime words sentences flesch summary cache txt cord-340279-bq5owwot Espíndola, Otávio de Melo Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid 2020-06-04 .txt text/plain 285 37 52 key: cord-340279-bq5owwot title: Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid cord_uid: bq5owwot Abstract We report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. • SARS-CoV-2 RNA is mainly undetectable in the cerebrospinal fluid. • SARS-CoV-2 clearance in the cerebrospinal fluid may precede the neurological involvement. • Common neuropathogens should be investigated in the CSF of COVID-19 patients. CSF analysis showed normal to mild elevated protein levels, and 86 pleocytosis was particularly observed in the cases of meningoencephalitis (Table 2) . Status of SARS-CoV-2 in 127 cerebrospinal fluid of patients with COVID-19 and stroke Guillain-Barré syndrome related 130 to COVID-19 infection Two patients with 132 acute meningo-encephalitis concomitant to SARS-CoV-2 infection Guillain-Barré syndrome as 137 a complication of SARS-CoV-2 infection Neurologic Features in Severe 141 SARS-CoV-2 Infection ./cache/cord-340279-bq5owwot.txt ./txt/cord-340279-bq5owwot.txt