id author title date pages extension mime words sentences flesch summary cache txt cord-007866-2d6003r9 Renz, Harald Autophagy: Nobel Prize 2016 and allergy and asthma research 2017-04-08 .txt text/plain 1053 67 47 The 2016 Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi, Professor at the Tokyo Institute of Technology, for ''recycling.'' Recycling on the cellular level is termed autophagy and is a fundamental process for degrading and recycling cellular components. A new type of vesicle was discovered and named autophagosomes, describing a process of ''self-eating'' to understand the mechanism of how such large cargos get into the lysosome. Although little work has been carried out in this regard thus far, there are convincing data available linking autophagy in airway epithelium, and autophagy might be essential for bronchial epithelial mucus secretion, as has been shown in an allergic asthma model. IL13 activates autophagy to regulate secretion in airway epithelial cells The complex roles of endoplasmic reticulum stress and autophagy in modulating Eotaxin-3 production and secretion from human airway epithelial cells ./cache/cord-007866-2d6003r9.txt ./txt/cord-007866-2d6003r9.txt