id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-264311-t81r2l3r	Toivonen, Laura	Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis	2019-01-14		.txt	text/plain	3590	188	40	To address the knowledge gap, we examined the association between rhinovirus species and the nasopharyngeal airway microbiota determined by 16S rRNA gene sequencing in 774 infants with severe bronchiolitis. Briefly, 1016 infants (age <1 year) hospitalized for bronchiolitis were enrolled in 17 sites across 14 US states (see Table E1 in this article's Online in PBMC-engrafted mice (n 5 14-16 per group) without or with injection of neutrophils and subsequent intranasal challenge with birch pollen extract (BPE) or PBS. 7 Our observations-for example, the association between RV-C and higher likelihood of Moraxella-dominant microbiota-corroborate these earlier findings, and extend them by applying 16S rRNA gene sequencing to the airway samples of a large multicenter prospective cohort of infants with severe bronchiolitis. Despite this complexity, the identification of the association between specific virus species and airway microbiota in infants with bronchiolitis is important given their relation to subsequent respiratory health in children.	./cache/cord-264311-t81r2l3r.txt	./txt/cord-264311-t81r2l3r.txt