id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265054-52eqdlef	Schaller, Matthew	Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response	2006-08-03		.txt	text/plain	5418	281	40	By this same theory, it has been demonstrated that chemokine levels produced during respiratory syncytial virus infection determine host responses to later immune stimuli in the lung, with the potential to augment the asthmatic response. 3 These studies are supported by clinical investigations that demonstrate that a relatively low number of influenza cases, versus RSV or rhinovirus infections, actually cause exacerbation of asthma and acute bronchiolitis in adults. A comparative study examining the effects of respiratory viruses on CXCL8 production found that although levels of CXCL8 protein in the nasal lavage fluid (NLF) of influenza virusand rhinovirus-infected patients correlated with a higher symptom score, this was not the case for RSV-infected patients. The recruitment of allergen-responsive T cells to the lung and draining lymph nodes has been linked to CCR1 in a murine model of RSV-induced exacerbation of allergic asthma (Schaller and Lukacs, unpublished data).	./cache/cord-265054-52eqdlef.txt	./txt/cord-265054-52eqdlef.txt