id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344759-7zs389m9	Shilts, Meghan H.	Nasopharyngeal Haemophilus and Local Immune Response during Infant Respiratory Syncytial Virus Infection	2020-07-03		.txt	text/plain	1817	111	50	128 129 One hundred and five (~34%) of the 309 infants with RSV-only ARIs enrolled in INSPIRE had 130 ≥1 nasal wash with 16S rRNA sequencing and immune mediator data available -obtained as Page 7 part of separate projects 5, 6 -and were thus included in our study. Cluster #1 also mainly included 147 infants with a higher relative abundance of Haemophilus in their nasopharynx (Figure 1) In unadjusted analyses, the nasopharyngeal relative abundance of Haemophilus was positively 152 correlated with the levels of 39 (~75%) of the 52 local immune mediators after controlling for 153 multiple comparisons (Figure 2A and Table E3 in the Online Repository). 8, 9 195 196 Our study has multiple strengths, including the population-based design of the parent study, the 197 close surveillance during the infants' first winter viral season to capture their initial RSV ARI, 198 the use of next-generation sequencing and high-throughput immune assays, and the use of 199 statistical analysis adjusting for potential confounders.	./cache/cord-344759-7zs389m9.txt	./txt/cord-344759-7zs389m9.txt