id sid tid token lemma pos cord-328210-qhl429fm 1 1 key key NN cord-328210-qhl429fm 1 2 : : : cord-328210-qhl429fm 2 1 cord-328210-qhl429fm cord-328210-qhl429fm NNP cord-328210-qhl429fm 2 2 authors author NNS cord-328210-qhl429fm 2 3 : : : cord-328210-qhl429fm 2 4 Gelardi Gelardi NNP cord-328210-qhl429fm 2 5 , , , cord-328210-qhl429fm 2 6 Matteo Matteo NNP cord-328210-qhl429fm 2 7 ; ; : cord-328210-qhl429fm 2 8 Cassano Cassano NNP cord-328210-qhl429fm 2 9 , , , cord-328210-qhl429fm 2 10 Michele Michele NNP cord-328210-qhl429fm 2 11 ; ; : cord-328210-qhl429fm 2 12 Ciprandi Ciprandi NNP cord-328210-qhl429fm 2 13 , , , cord-328210-qhl429fm 2 14 Giorgio Giorgio NNP cord-328210-qhl429fm 2 15 title title NN cord-328210-qhl429fm 2 16 : : : cord-328210-qhl429fm 3 1 The the DT cord-328210-qhl429fm 3 2 clinical clinical JJ cord-328210-qhl429fm 3 3 relevance relevance NN cord-328210-qhl429fm 3 4 of of IN cord-328210-qhl429fm 3 5 the the DT cord-328210-qhl429fm 3 6 clinical clinical JJ cord-328210-qhl429fm 3 7 cytological cytological JJ cord-328210-qhl429fm 3 8 grading grading NN cord-328210-qhl429fm 3 9 in in IN cord-328210-qhl429fm 3 10 patients patient NNS cord-328210-qhl429fm 3 11 with with IN cord-328210-qhl429fm 3 12 chronic chronic JJ cord-328210-qhl429fm 3 13 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 3 14 with with IN cord-328210-qhl429fm 3 15 nasal nasal JJ cord-328210-qhl429fm 3 16 polyps polyp NNS cord-328210-qhl429fm 3 17 date date NN cord-328210-qhl429fm 3 18 : : : cord-328210-qhl429fm 3 19 2020 2020 CD cord-328210-qhl429fm 3 20 - - HYPH cord-328210-qhl429fm 3 21 06 06 CD cord-328210-qhl429fm 3 22 - - HYPH cord-328210-qhl429fm 3 23 24 24 CD cord-328210-qhl429fm 3 24 journal journal NN cord-328210-qhl429fm 3 25 : : : cord-328210-qhl429fm 4 1 J J NNP cord-328210-qhl429fm 4 2 Allergy Allergy NNP cord-328210-qhl429fm 4 3 Clin Clin NNP cord-328210-qhl429fm 4 4 Immunol Immunol NNP cord-328210-qhl429fm 4 5 DOI DOI NNP cord-328210-qhl429fm 4 6 : : : cord-328210-qhl429fm 4 7 10.1016 10.1016 CD cord-328210-qhl429fm 4 8 / / SYM cord-328210-qhl429fm 4 9 j.jaci.2020.04.049 j.jaci.2020.04.049 XX cord-328210-qhl429fm 4 10 sha sha NNP cord-328210-qhl429fm 4 11 : : : cord-328210-qhl429fm 4 12 cca4c7aa2d13ec7e15f6e39e7c154ec050bb6278 cca4c7aa2d13ec7e15f6e39e7c154ec050bb6278 NFP cord-328210-qhl429fm 4 13 doc_id doc_id CD cord-328210-qhl429fm 4 14 : : : cord-328210-qhl429fm 4 15 328210 328210 CD cord-328210-qhl429fm 4 16 cord_uid cord_uid NNS cord-328210-qhl429fm 4 17 : : : cord-328210-qhl429fm 5 1 qhl429fm qhl429fm NNP cord-328210-qhl429fm 5 2 nan nan NNP cord-328210-qhl429fm 6 1 The the DT cord-328210-qhl429fm 6 2 clinical clinical JJ cord-328210-qhl429fm 6 3 relevance relevance NN cord-328210-qhl429fm 6 4 of of IN cord-328210-qhl429fm 6 5 the the DT cord-328210-qhl429fm 6 6 clinical clinical JJ cord-328210-qhl429fm 6 7 cytological cytological JJ cord-328210-qhl429fm 6 8 grading grading NN cord-328210-qhl429fm 6 9 in in IN cord-328210-qhl429fm 6 10 patients patient NNS cord-328210-qhl429fm 6 11 with with IN cord-328210-qhl429fm 6 12 chronic chronic JJ cord-328210-qhl429fm 6 13 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 6 14 with with IN cord-328210-qhl429fm 6 15 nasal nasal NN cord-328210-qhl429fm 6 16 polyps polyp NNS cord-328210-qhl429fm 6 17 To to IN cord-328210-qhl429fm 6 18 the the DT cord-328210-qhl429fm 6 19 Editor editor NN cord-328210-qhl429fm 6 20 : : : cord-328210-qhl429fm 6 21 Smell Smell NNP cord-328210-qhl429fm 6 22 dysfunction dysfunction NN cord-328210-qhl429fm 6 23 is be VBZ cord-328210-qhl429fm 6 24 a a DT cord-328210-qhl429fm 6 25 common common JJ cord-328210-qhl429fm 6 26 symptom symptom NN cord-328210-qhl429fm 6 27 and and CC cord-328210-qhl429fm 6 28 has have VBZ cord-328210-qhl429fm 6 29 a a DT cord-328210-qhl429fm 6 30 diagnostic diagnostic JJ cord-328210-qhl429fm 6 31 value value NN cord-328210-qhl429fm 6 32 in in IN cord-328210-qhl429fm 6 33 the the DT cord-328210-qhl429fm 6 34 workup workup NN cord-328210-qhl429fm 6 35 of of IN cord-328210-qhl429fm 6 36 patients patient NNS cord-328210-qhl429fm 6 37 with with IN cord-328210-qhl429fm 6 38 chronic chronic JJ cord-328210-qhl429fm 6 39 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 6 40 with with IN cord-328210-qhl429fm 6 41 nasal nasal NN cord-328210-qhl429fm 6 42 polyps polyp NNS cord-328210-qhl429fm 6 43 ( ( -LRB- cord-328210-qhl429fm 6 44 CRSwNP crswnp RB cord-328210-qhl429fm 6 45 ) ) -RRB- cord-328210-qhl429fm 6 46 as as IN cord-328210-qhl429fm 6 47 recently recently RB cord-328210-qhl429fm 6 48 outlined outline VBN cord-328210-qhl429fm 6 49 by by IN cord-328210-qhl429fm 6 50 Mullol Mullol NNP cord-328210-qhl429fm 6 51 et et NNP cord-328210-qhl429fm 6 52 al al NNP cord-328210-qhl429fm 6 53 . . . cord-328210-qhl429fm 7 1 1 1 LS cord-328210-qhl429fm 8 1 Notably notably RB cord-328210-qhl429fm 8 2 , , , cord-328210-qhl429fm 8 3 loss loss NN cord-328210-qhl429fm 8 4 of of IN cord-328210-qhl429fm 8 5 smell smell NN cord-328210-qhl429fm 8 6 has have VBZ cord-328210-qhl429fm 8 7 been be VBN cord-328210-qhl429fm 8 8 proposed propose VBN cord-328210-qhl429fm 8 9 as as IN cord-328210-qhl429fm 8 10 one one CD cord-328210-qhl429fm 8 11 of of IN cord-328210-qhl429fm 8 12 the the DT cord-328210-qhl429fm 8 13 main main JJ cord-328210-qhl429fm 8 14 criteria criterion NNS cord-328210-qhl429fm 8 15 for for IN cord-328210-qhl429fm 8 16 an an DT cord-328210-qhl429fm 8 17 indication indication NN cord-328210-qhl429fm 8 18 of of IN cord-328210-qhl429fm 8 19 and and CC cord-328210-qhl429fm 8 20 response response NN cord-328210-qhl429fm 8 21 to to IN cord-328210-qhl429fm 8 22 the the DT cord-328210-qhl429fm 8 23 new new JJ cord-328210-qhl429fm 8 24 biological biological JJ cord-328210-qhl429fm 8 25 treatments treatment NNS cord-328210-qhl429fm 8 26 . . . cord-328210-qhl429fm 9 1 2 2 LS cord-328210-qhl429fm 10 1 Of of IN cord-328210-qhl429fm 10 2 note note NN cord-328210-qhl429fm 10 3 , , , cord-328210-qhl429fm 10 4 it -PRON- PRP cord-328210-qhl429fm 10 5 has have VBZ cord-328210-qhl429fm 10 6 been be VBN cord-328210-qhl429fm 10 7 very very RB cord-328210-qhl429fm 10 8 recently recently RB cord-328210-qhl429fm 10 9 reported report VBN cord-328210-qhl429fm 10 10 that that IN cord-328210-qhl429fm 10 11 a a DT cord-328210-qhl429fm 10 12 significant significant JJ cord-328210-qhl429fm 10 13 part part NN cord-328210-qhl429fm 10 14 ( ( -LRB- cord-328210-qhl429fm 10 15 20%-60 20%-60 CD cord-328210-qhl429fm 10 16 % % NN cord-328210-qhl429fm 10 17 ) ) -RRB- cord-328210-qhl429fm 10 18 of of IN cord-328210-qhl429fm 10 19 the the DT cord-328210-qhl429fm 10 20 patients patient NNS cord-328210-qhl429fm 10 21 with with IN cord-328210-qhl429fm 10 22 coronavirus coronavirus NN cord-328210-qhl429fm 10 23 disease disease NN cord-328210-qhl429fm 10 24 2019 2019 CD cord-328210-qhl429fm 10 25 ( ( -LRB- cord-328210-qhl429fm 10 26 COVID-19 COVID-19 NNP cord-328210-qhl429fm 10 27 ) ) -RRB- cord-328210-qhl429fm 10 28 experienced experience VBD cord-328210-qhl429fm 10 29 the the DT cord-328210-qhl429fm 10 30 loss loss NN cord-328210-qhl429fm 10 31 of of IN cord-328210-qhl429fm 10 32 smell smell NN cord-328210-qhl429fm 10 33 ; ; : cord-328210-qhl429fm 10 34 anosmia anosmia NN cord-328210-qhl429fm 10 35 can can MD cord-328210-qhl429fm 10 36 be be VB cord-328210-qhl429fm 10 37 the the DT cord-328210-qhl429fm 10 38 first first JJ cord-328210-qhl429fm 10 39 presenting presenting JJ cord-328210-qhl429fm 10 40 symptom symptom NN cord-328210-qhl429fm 10 41 and and CC cord-328210-qhl429fm 10 42 so so RB cord-328210-qhl429fm 10 43 the the DT cord-328210-qhl429fm 10 44 European European NNP cord-328210-qhl429fm 10 45 Rhinologic Rhinologic NNP cord-328210-qhl429fm 10 46 Society Society NNP cord-328210-qhl429fm 10 47 advised advise VBD cord-328210-qhl429fm 10 48 that that IN cord-328210-qhl429fm 10 49 patients patient NNS cord-328210-qhl429fm 10 50 with with IN cord-328210-qhl429fm 10 51 sudden sudden JJ cord-328210-qhl429fm 10 52 - - HYPH cord-328210-qhl429fm 10 53 onset onset NN cord-328210-qhl429fm 10 54 loss loss NN cord-328210-qhl429fm 10 55 of of IN cord-328210-qhl429fm 10 56 smell smell NN cord-328210-qhl429fm 10 57 should should MD cord-328210-qhl429fm 10 58 be be VB cord-328210-qhl429fm 10 59 considered consider VBN cord-328210-qhl429fm 10 60 to to TO cord-328210-qhl429fm 10 61 be be VB cord-328210-qhl429fm 10 62 COVID-19 COVID-19 NNP cord-328210-qhl429fm 10 63 positive positive JJ cord-328210-qhl429fm 10 64 ( ( -LRB- cord-328210-qhl429fm 10 65 www.europeanrhino www.europeanrhino NNP cord-328210-qhl429fm 11 1 logicsociety.org logicsociety.org LS cord-328210-qhl429fm 11 2 ) ) -RRB- cord-328210-qhl429fm 11 3 . . . cord-328210-qhl429fm 12 1 CRSwNP CRSwNP NNP cord-328210-qhl429fm 12 2 is be VBZ cord-328210-qhl429fm 12 3 characterized characterize VBN cord-328210-qhl429fm 12 4 by by IN cord-328210-qhl429fm 12 5 a a DT cord-328210-qhl429fm 12 6 type type NN cord-328210-qhl429fm 12 7 2 2 CD cord-328210-qhl429fm 12 8 inflammation inflammation NN cord-328210-qhl429fm 12 9 and and CC cord-328210-qhl429fm 12 10 is be VBZ cord-328210-qhl429fm 12 11 frequently frequently RB cord-328210-qhl429fm 12 12 associated associate VBN cord-328210-qhl429fm 12 13 with with IN cord-328210-qhl429fm 12 14 some some DT cord-328210-qhl429fm 12 15 comorbidity comorbidity NN cord-328210-qhl429fm 12 16 , , , cord-328210-qhl429fm 12 17 including include VBG cord-328210-qhl429fm 12 18 asthma asthma NN cord-328210-qhl429fm 12 19 , , , cord-328210-qhl429fm 12 20 aspirin aspirin NN cord-328210-qhl429fm 12 21 sensitivity sensitivity NN cord-328210-qhl429fm 12 22 , , , cord-328210-qhl429fm 12 23 and and CC cord-328210-qhl429fm 12 24 allergy allergy NN cord-328210-qhl429fm 12 25 . . . cord-328210-qhl429fm 13 1 3 3 LS cord-328210-qhl429fm 13 2 Type type NN cord-328210-qhl429fm 13 3 2 2 CD cord-328210-qhl429fm 13 4 inflammation inflammation NN cord-328210-qhl429fm 13 5 leads lead VBZ cord-328210-qhl429fm 13 6 to to IN cord-328210-qhl429fm 13 7 eosinophils eosinophils NN cord-328210-qhl429fm 13 8 and and CC cord-328210-qhl429fm 13 9 mast mast NN cord-328210-qhl429fm 13 10 cells cell NNS cord-328210-qhl429fm 13 11 recruitment recruitment NN cord-328210-qhl429fm 13 12 and and CC cord-328210-qhl429fm 13 13 activation activation NN cord-328210-qhl429fm 13 14 in in IN cord-328210-qhl429fm 13 15 upper upper JJ cord-328210-qhl429fm 13 16 airways airway NNS cord-328210-qhl429fm 13 17 . . . cord-328210-qhl429fm 14 1 Therefore therefore RB cord-328210-qhl429fm 14 2 , , , cord-328210-qhl429fm 14 3 to to TO cord-328210-qhl429fm 14 4 document document VB cord-328210-qhl429fm 14 5 the the DT cord-328210-qhl429fm 14 6 presence presence NN cord-328210-qhl429fm 14 7 of of IN cord-328210-qhl429fm 14 8 inflammatory inflammatory JJ cord-328210-qhl429fm 14 9 cells cell NNS cord-328210-qhl429fm 14 10 in in IN cord-328210-qhl429fm 14 11 the the DT cord-328210-qhl429fm 14 12 nose nose NN cord-328210-qhl429fm 14 13 by by IN cord-328210-qhl429fm 14 14 nasal nasal NN cord-328210-qhl429fm 14 15 cytology cytology NN cord-328210-qhl429fm 14 16 is be VBZ cord-328210-qhl429fm 14 17 a a DT cord-328210-qhl429fm 14 18 simple simple JJ cord-328210-qhl429fm 14 19 and and CC cord-328210-qhl429fm 14 20 fruitful fruitful JJ cord-328210-qhl429fm 14 21 way way NN cord-328210-qhl429fm 14 22 to to TO cord-328210-qhl429fm 14 23 assess assess VB cord-328210-qhl429fm 14 24 the the DT cord-328210-qhl429fm 14 25 severity severity NN cord-328210-qhl429fm 14 26 of of IN cord-328210-qhl429fm 14 27 disease disease NN cord-328210-qhl429fm 14 28 and and CC cord-328210-qhl429fm 14 29 evaluate evaluate VB cord-328210-qhl429fm 14 30 the the DT cord-328210-qhl429fm 14 31 response response NN cord-328210-qhl429fm 14 32 to to IN cord-328210-qhl429fm 14 33 treatments treatment NNS cord-328210-qhl429fm 14 34 . . . cord-328210-qhl429fm 15 1 4 4 LS cord-328210-qhl429fm 16 1 Nasal nasal NN cord-328210-qhl429fm 16 2 cytology cytology NN cord-328210-qhl429fm 16 3 is be VBZ cord-328210-qhl429fm 16 4 a a DT cord-328210-qhl429fm 16 5 wellstandardized wellstandardized JJ cord-328210-qhl429fm 16 6 method method NN cord-328210-qhl429fm 16 7 that that WDT cord-328210-qhl429fm 16 8 may may MD cord-328210-qhl429fm 16 9 be be VB cord-328210-qhl429fm 16 10 applied apply VBN cord-328210-qhl429fm 16 11 to to IN cord-328210-qhl429fm 16 12 all all DT cord-328210-qhl429fm 16 13 nasal nasal JJ cord-328210-qhl429fm 16 14 inflammatory inflammatory JJ cord-328210-qhl429fm 16 15 disorders disorder NNS cord-328210-qhl429fm 16 16 . . . cord-328210-qhl429fm 17 1 5 5 LS cord-328210-qhl429fm 18 1 Therefore therefore RB cord-328210-qhl429fm 18 2 , , , cord-328210-qhl429fm 18 3 nasal nasal NN cord-328210-qhl429fm 18 4 cytology cytology NN cord-328210-qhl429fm 18 5 may may MD cord-328210-qhl429fm 18 6 be be VB cord-328210-qhl429fm 18 7 performed perform VBN cord-328210-qhl429fm 18 8 as as IN cord-328210-qhl429fm 18 9 a a DT cord-328210-qhl429fm 18 10 useful useful JJ cord-328210-qhl429fm 18 11 step step NN cord-328210-qhl429fm 18 12 in in IN cord-328210-qhl429fm 18 13 the the DT cord-328210-qhl429fm 18 14 workup workup NN cord-328210-qhl429fm 18 15 of of IN cord-328210-qhl429fm 18 16 patients patient NNS cord-328210-qhl429fm 18 17 with with IN cord-328210-qhl429fm 18 18 CRSwNP crswnp NN cord-328210-qhl429fm 18 19 . . . cord-328210-qhl429fm 19 1 As as IN cord-328210-qhl429fm 19 2 a a DT cord-328210-qhl429fm 19 3 consequence consequence NN cord-328210-qhl429fm 19 4 , , , cord-328210-qhl429fm 19 5 a a DT cord-328210-qhl429fm 19 6 clinical clinical JJ cord-328210-qhl429fm 19 7 cytological cytological JJ cord-328210-qhl429fm 19 8 grading grading NN cord-328210-qhl429fm 19 9 ( ( -LRB- cord-328210-qhl429fm 19 10 CCG CCG NNP cord-328210-qhl429fm 19 11 ) ) -RRB- cord-328210-qhl429fm 19 12 , , , cord-328210-qhl429fm 19 13 including include VBG cord-328210-qhl429fm 19 14 the the DT cord-328210-qhl429fm 19 15 documentation documentation NN cord-328210-qhl429fm 19 16 of of IN cord-328210-qhl429fm 19 17 possible possible JJ cord-328210-qhl429fm 19 18 asthma asthma NN cord-328210-qhl429fm 19 19 , , , cord-328210-qhl429fm 19 20 allergy allergy NN cord-328210-qhl429fm 19 21 , , , cord-328210-qhl429fm 19 22 or or CC cord-328210-qhl429fm 19 23 aspirin aspirin NN cord-328210-qhl429fm 19 24 sensitivity sensitivity NN cord-328210-qhl429fm 19 25 comorbidity comorbidity NN cord-328210-qhl429fm 19 26 , , , cord-328210-qhl429fm 19 27 and and CC cord-328210-qhl429fm 19 28 the the DT cord-328210-qhl429fm 19 29 presence presence NN cord-328210-qhl429fm 19 30 of of IN cord-328210-qhl429fm 19 31 eosinophils eosinophil NNS cord-328210-qhl429fm 19 32 and/or and/or CC cord-328210-qhl429fm 19 33 mast mast NN cord-328210-qhl429fm 19 34 cells cell NNS cord-328210-qhl429fm 19 35 in in IN cord-328210-qhl429fm 19 36 the the DT cord-328210-qhl429fm 19 37 nose nose NN cord-328210-qhl429fm 19 38 , , , cord-328210-qhl429fm 19 39 has have VBZ cord-328210-qhl429fm 19 40 been be VBN cord-328210-qhl429fm 19 41 proposed propose VBN cord-328210-qhl429fm 19 42 as as IN cord-328210-qhl429fm 19 43 a a DT cord-328210-qhl429fm 19 44 precision precision NN cord-328210-qhl429fm 19 45 medicine medicine NN cord-328210-qhl429fm 19 46 - - HYPH cord-328210-qhl429fm 19 47 based base VBN cord-328210-qhl429fm 19 48 approach approach NN cord-328210-qhl429fm 19 49 in in IN cord-328210-qhl429fm 19 50 the the DT cord-328210-qhl429fm 19 51 management management NN cord-328210-qhl429fm 19 52 of of IN cord-328210-qhl429fm 19 53 patients patient NNS cord-328210-qhl429fm 19 54 with with IN cord-328210-qhl429fm 19 55 CRSwNP crswnp NN cord-328210-qhl429fm 19 56 . . . cord-328210-qhl429fm 19 57 6 6 CD cord-328210-qhl429fm 20 1 In in IN cord-328210-qhl429fm 20 2 particular particular JJ cord-328210-qhl429fm 20 3 , , , cord-328210-qhl429fm 20 4 3 3 CD cord-328210-qhl429fm 20 5 CCG CCG NNP cord-328210-qhl429fm 20 6 grades grade NNS cord-328210-qhl429fm 20 7 were be VBD cord-328210-qhl429fm 20 8 defined define VBN cord-328210-qhl429fm 20 9 on on IN cord-328210-qhl429fm 20 10 the the DT cord-328210-qhl429fm 20 11 basis basis NN cord-328210-qhl429fm 20 12 of of IN cord-328210-qhl429fm 20 13 the the DT cord-328210-qhl429fm 20 14 score score NN cord-328210-qhl429fm 20 15 : : : cord-328210-qhl429fm 20 16 low low JJ cord-328210-qhl429fm 20 17 ( ( -LRB- cord-328210-qhl429fm 20 18 1 1 CD cord-328210-qhl429fm 20 19 - - SYM cord-328210-qhl429fm 20 20 3 3 CD cord-328210-qhl429fm 20 21 ) ) -RRB- cord-328210-qhl429fm 20 22 , , , cord-328210-qhl429fm 20 23 medium medium NN cord-328210-qhl429fm 20 24 ( ( -LRB- cord-328210-qhl429fm 20 25 4 4 CD cord-328210-qhl429fm 20 26 - - SYM cord-328210-qhl429fm 20 27 6 6 CD cord-328210-qhl429fm 20 28 ) ) -RRB- cord-328210-qhl429fm 20 29 , , , cord-328210-qhl429fm 20 30 and and CC cord-328210-qhl429fm 20 31 high high JJ cord-328210-qhl429fm 20 32 ( ( -LRB- cord-328210-qhl429fm 20 33 > > XX cord-328210-qhl429fm 20 34 _ _ NN cord-328210-qhl429fm 20 35 7 7 CD cord-328210-qhl429fm 20 36 ) ) -RRB- cord-328210-qhl429fm 20 37 . . . cord-328210-qhl429fm 21 1 A a DT cord-328210-qhl429fm 21 2 recent recent JJ cord-328210-qhl429fm 21 3 study study NN cord-328210-qhl429fm 21 4 provided provide VBD cord-328210-qhl429fm 21 5 evidence evidence NN cord-328210-qhl429fm 21 6 that that IN cord-328210-qhl429fm 21 7 a a DT cord-328210-qhl429fm 21 8 CCG CCG NNP cord-328210-qhl429fm 21 9 value value NN cord-328210-qhl429fm 21 10 of of IN cord-328210-qhl429fm 21 11 more more JJR cord-328210-qhl429fm 21 12 than than IN cord-328210-qhl429fm 21 13 4 4 CD cord-328210-qhl429fm 21 14 was be VBD cord-328210-qhl429fm 21 15 a a DT cord-328210-qhl429fm 21 16 reliable reliable JJ cord-328210-qhl429fm 21 17 ( ( -LRB- cord-328210-qhl429fm 21 18 area area NN cord-328210-qhl429fm 21 19 under under IN cord-328210-qhl429fm 21 20 the the DT cord-328210-qhl429fm 21 21 curve curve NN cord-328210-qhl429fm 21 22 , , , cord-328210-qhl429fm 21 23 0.83 0.83 CD cord-328210-qhl429fm 21 24 , , , cord-328210-qhl429fm 21 25 and and CC cord-328210-qhl429fm 21 26 adjusted adjust VBN cord-328210-qhl429fm 21 27 odds odd NNS cord-328210-qhl429fm 21 28 ratio ratio NN cord-328210-qhl429fm 21 29 , , , cord-328210-qhl429fm 21 30 7.46 7.46 CD cord-328210-qhl429fm 21 31 ) ) -RRB- cord-328210-qhl429fm 21 32 cutoff cutoff NN cord-328210-qhl429fm 21 33 to to TO cord-328210-qhl429fm 21 34 identify identify VB cord-328210-qhl429fm 21 35 patients patient NNS cord-328210-qhl429fm 21 36 with with IN cord-328210-qhl429fm 21 37 CRSwNP CRSwNP VBN cord-328210-qhl429fm 21 38 with with IN cord-328210-qhl429fm 21 39 olfactory olfactory JJ cord-328210-qhl429fm 21 40 dysfunction dysfunction NN cord-328210-qhl429fm 21 41 . . . cord-328210-qhl429fm 22 1 7 7 CD cord-328210-qhl429fm 23 1 Smell smell JJ cord-328210-qhl429fm 23 2 loss loss NN cord-328210-qhl429fm 23 3 is be VBZ cord-328210-qhl429fm 23 4 a a DT cord-328210-qhl429fm 23 5 clinical clinical JJ cord-328210-qhl429fm 23 6 marker marker NN cord-328210-qhl429fm 23 7 of of IN cord-328210-qhl429fm 23 8 CRSwNP crswnp JJ cord-328210-qhl429fm 23 9 severity severity NN cord-328210-qhl429fm 23 10 and and CC cord-328210-qhl429fm 23 11 is be VBZ cord-328210-qhl429fm 23 12 associated associate VBN cord-328210-qhl429fm 23 13 with with IN cord-328210-qhl429fm 23 14 type type NN cord-328210-qhl429fm 23 15 2 2 CD cord-328210-qhl429fm 23 16 inflammation inflammation NN cord-328210-qhl429fm 23 17 : : : cord-328210-qhl429fm 23 18 both both DT cord-328210-qhl429fm 23 19 conditions condition NNS cord-328210-qhl429fm 23 20 indicate indicate VBP cord-328210-qhl429fm 23 21 a a DT cord-328210-qhl429fm 23 22 biological biological JJ cord-328210-qhl429fm 23 23 approach approach NN cord-328210-qhl429fm 23 24 . . . cord-328210-qhl429fm 24 1 1 1 LS cord-328210-qhl429fm 25 1 The the DT cord-328210-qhl429fm 25 2 CRSwNP crswnp JJ cord-328210-qhl429fm 25 3 overall overall JJ cord-328210-qhl429fm 25 4 prevalence prevalence NN cord-328210-qhl429fm 25 5 has have VBZ cord-328210-qhl429fm 25 6 been be VBN cord-328210-qhl429fm 25 7 approximately approximately RB cord-328210-qhl429fm 25 8 estimated estimate VBN cord-328210-qhl429fm 25 9 to to TO cord-328210-qhl429fm 25 10 be be VB cord-328210-qhl429fm 25 11 2 2 CD cord-328210-qhl429fm 25 12 % % NN cord-328210-qhl429fm 25 13 to to TO cord-328210-qhl429fm 25 14 4 4 CD cord-328210-qhl429fm 25 15 % % NN cord-328210-qhl429fm 25 16 of of IN cord-328210-qhl429fm 25 17 the the DT cord-328210-qhl429fm 25 18 general general JJ cord-328210-qhl429fm 25 19 population population NN cord-328210-qhl429fm 25 20 and and CC cord-328210-qhl429fm 25 21 approximately approximately RB cord-328210-qhl429fm 25 22 30 30 CD cord-328210-qhl429fm 25 23 % % NN cord-328210-qhl429fm 25 24 of of IN cord-328210-qhl429fm 25 25 these these DT cord-328210-qhl429fm 25 26 patients patient NNS cord-328210-qhl429fm 25 27 also also RB cord-328210-qhl429fm 25 28 have have VBP cord-328210-qhl429fm 25 29 asthma asthma NN cord-328210-qhl429fm 25 30 . . . cord-328210-qhl429fm 26 1 2 2 LS cord-328210-qhl429fm 27 1 On on IN cord-328210-qhl429fm 27 2 the the DT cord-328210-qhl429fm 27 3 basis basis NN cord-328210-qhl429fm 27 4 of of IN cord-328210-qhl429fm 27 5 these these DT cord-328210-qhl429fm 27 6 epidemiological epidemiological JJ cord-328210-qhl429fm 27 7 considerations consideration NNS cord-328210-qhl429fm 27 8 , , , cord-328210-qhl429fm 27 9 a a DT cord-328210-qhl429fm 27 10 large large JJ cord-328210-qhl429fm 27 11 group group NN cord-328210-qhl429fm 27 12 of of IN cord-328210-qhl429fm 27 13 Italian italian JJ cord-328210-qhl429fm 27 14 outpatients outpatient NNS cord-328210-qhl429fm 27 15 with with IN cord-328210-qhl429fm 27 16 CRSwNP crswnp NN cord-328210-qhl429fm 27 17 ( ( -LRB- cord-328210-qhl429fm 27 18 791 791 CD cord-328210-qhl429fm 27 19 ; ; : cord-328210-qhl429fm 27 20 424 424 CD cord-328210-qhl429fm 27 21 males male NNS cord-328210-qhl429fm 27 22 , , , cord-328210-qhl429fm 27 23 mean mean VB cord-328210-qhl429fm 27 24 age age NN cord-328210-qhl429fm 27 25 , , , cord-328210-qhl429fm 27 26 48.8 48.8 CD cord-328210-qhl429fm 27 27 years year NNS cord-328210-qhl429fm 27 28 ) ) -RRB- cord-328210-qhl429fm 27 29 was be VBD cord-328210-qhl429fm 27 30 recruited recruit VBN cord-328210-qhl429fm 27 31 in in IN cord-328210-qhl429fm 27 32 a a DT cord-328210-qhl429fm 27 33 real real JJ cord-328210-qhl429fm 27 34 - - HYPH cord-328210-qhl429fm 27 35 world world NN cord-328210-qhl429fm 27 36 study study NN cord-328210-qhl429fm 27 37 to to TO cord-328210-qhl429fm 27 38 define define VB cord-328210-qhl429fm 27 39 the the DT cord-328210-qhl429fm 27 40 distribution distribution NN cord-328210-qhl429fm 27 41 of of IN cord-328210-qhl429fm 27 42 the the DT cord-328210-qhl429fm 27 43 CCG CCG NNP cord-328210-qhl429fm 27 44 grades grade NNS cord-328210-qhl429fm 27 45 . . . cord-328210-qhl429fm 28 1 The the DT cord-328210-qhl429fm 28 2 preliminary preliminary JJ cord-328210-qhl429fm 28 3 results result NNS cord-328210-qhl429fm 28 4 showed show VBD cord-328210-qhl429fm 28 5 that that IN cord-328210-qhl429fm 28 6 210 210 CD cord-328210-qhl429fm 28 7 ( ( -LRB- cord-328210-qhl429fm 28 8 26.5 26.5 CD cord-328210-qhl429fm 28 9 % % NN cord-328210-qhl429fm 28 10 ) ) -RRB- cord-328210-qhl429fm 28 11 outpatients outpatient NNS cord-328210-qhl429fm 28 12 had have VBD cord-328210-qhl429fm 28 13 low low JJ cord-328210-qhl429fm 28 14 - - HYPH cord-328210-qhl429fm 28 15 grade grade NN cord-328210-qhl429fm 28 16 CCG CCG NNP cord-328210-qhl429fm 28 17 , , , cord-328210-qhl429fm 28 18 366 366 CD cord-328210-qhl429fm 28 19 ( ( -LRB- cord-328210-qhl429fm 28 20 46.3 46.3 CD cord-328210-qhl429fm 28 21 % % NN cord-328210-qhl429fm 28 22 ) ) -RRB- cord-328210-qhl429fm 28 23 medium medium NN cord-328210-qhl429fm 28 24 , , , cord-328210-qhl429fm 28 25 and and CC cord-328210-qhl429fm 28 26 215 215 CD cord-328210-qhl429fm 28 27 ( ( -LRB- cord-328210-qhl429fm 28 28 27.2 27.2 CD cord-328210-qhl429fm 28 29 % % NN cord-328210-qhl429fm 28 30 ) ) -RRB- cord-328210-qhl429fm 28 31 high high JJ cord-328210-qhl429fm 29 1 ( ( -LRB- cord-328210-qhl429fm 29 2 Fig Fig NNP cord-328210-qhl429fm 29 3 1 1 CD cord-328210-qhl429fm 29 4 ) ) -RRB- cord-328210-qhl429fm 29 5 . . . cord-328210-qhl429fm 30 1 High high JJ cord-328210-qhl429fm 30 2 - - HYPH cord-328210-qhl429fm 30 3 grade grade NN cord-328210-qhl429fm 30 4 CCG CCG NNP cord-328210-qhl429fm 30 5 was be VBD cord-328210-qhl429fm 30 6 frequently frequently RB cord-328210-qhl429fm 30 7 characterized characterize VBN cord-328210-qhl429fm 30 8 by by IN cord-328210-qhl429fm 30 9 mixed mixed JJ cord-328210-qhl429fm 30 10 cytological cytological JJ cord-328210-qhl429fm 30 11 phenotype phenotype NN cord-328210-qhl429fm 30 12 and and CC cord-328210-qhl429fm 30 13 severe severe JJ cord-328210-qhl429fm 30 14 progress progress NN cord-328210-qhl429fm 30 15 . . . cord-328210-qhl429fm 31 1 Patients patient NNS cord-328210-qhl429fm 31 2 with with IN cord-328210-qhl429fm 31 3 CRSwNP CRSwNP NNP cord-328210-qhl429fm 31 4 deserve deserve VB cord-328210-qhl429fm 31 5 adequate adequate JJ cord-328210-qhl429fm 31 6 management management NN cord-328210-qhl429fm 31 7 and and CC cord-328210-qhl429fm 31 8 optimal optimal JJ cord-328210-qhl429fm 31 9 identification identification NN cord-328210-qhl429fm 31 10 of of IN cord-328210-qhl429fm 31 11 the the DT cord-328210-qhl429fm 31 12 besttailored besttailored JJ cord-328210-qhl429fm 31 13 therapy therapy NN cord-328210-qhl429fm 31 14 ; ; : cord-328210-qhl429fm 31 15 in in IN cord-328210-qhl429fm 31 16 this this DT cord-328210-qhl429fm 31 17 regard regard NN cord-328210-qhl429fm 31 18 , , , cord-328210-qhl429fm 31 19 CCG CCG NNP cord-328210-qhl429fm 31 20 could could MD cord-328210-qhl429fm 31 21 be be VB cord-328210-qhl429fm 31 22 a a DT cord-328210-qhl429fm 31 23 fruitful fruitful JJ cord-328210-qhl429fm 31 24 tool tool NN cord-328210-qhl429fm 31 25 . . . cord-328210-qhl429fm 32 1 In in IN cord-328210-qhl429fm 32 2 particular particular JJ cord-328210-qhl429fm 32 3 , , , cord-328210-qhl429fm 32 4 considering consider VBG cord-328210-qhl429fm 32 5 the the DT cord-328210-qhl429fm 32 6 estimated estimate VBN cord-328210-qhl429fm 32 7 prevalence prevalence NN cord-328210-qhl429fm 32 8 of of IN cord-328210-qhl429fm 32 9 CRSwNP crswnp NN cord-328210-qhl429fm 32 10 and and CC cord-328210-qhl429fm 32 11 the the DT cord-328210-qhl429fm 32 12 current current JJ cord-328210-qhl429fm 32 13 findings finding NNS cord-328210-qhl429fm 32 14 , , , cord-328210-qhl429fm 32 15 it -PRON- PRP cord-328210-qhl429fm 32 16 could could MD cord-328210-qhl429fm 32 17 be be VB cord-328210-qhl429fm 32 18 reasonably reasonably RB cord-328210-qhl429fm 32 19 expected expect VBN cord-328210-qhl429fm 32 20 that that IN cord-328210-qhl429fm 32 21 at at RB cord-328210-qhl429fm 32 22 least least JJS cord-328210-qhl429fm 32 23 5 5 CD cord-328210-qhl429fm 32 24 million million CD cord-328210-qhl429fm 32 25 Europeans Europeans NNPS cord-328210-qhl429fm 32 26 have have VBP cord-328210-qhl429fm 32 27 CRSwNP CRSwNP VBN cord-328210-qhl429fm 32 28 with with IN cord-328210-qhl429fm 32 29 high high JJ cord-328210-qhl429fm 32 30 - - HYPH cord-328210-qhl429fm 32 31 grade grade NN cord-328210-qhl429fm 32 32 CCG ccg NN cord-328210-qhl429fm 32 33 . . . cord-328210-qhl429fm 33 1 Therefore therefore RB cord-328210-qhl429fm 33 2 , , , cord-328210-qhl429fm 33 3 intercepting intercept VBG cord-328210-qhl429fm 33 4 the the DT cord-328210-qhl429fm 33 5 most most RBS cord-328210-qhl429fm 33 6 severe severe JJ cord-328210-qhl429fm 33 7 patients patient NNS cord-328210-qhl429fm 33 8 and and CC cord-328210-qhl429fm 33 9 launching launch VBG cord-328210-qhl429fm 33 10 an an DT cord-328210-qhl429fm 33 11 early early JJ cord-328210-qhl429fm 33 12 and and CC cord-328210-qhl429fm 33 13 tailored tailor VBN cord-328210-qhl429fm 33 14 treatment treatment NN cord-328210-qhl429fm 33 15 , , , cord-328210-qhl429fm 33 16 including include VBG cord-328210-qhl429fm 33 17 the the DT cord-328210-qhl429fm 33 18 new new JJ cord-328210-qhl429fm 33 19 biologics biologic NNS cord-328210-qhl429fm 33 20 , , , cord-328210-qhl429fm 33 21 could could MD cord-328210-qhl429fm 33 22 positively positively RB cord-328210-qhl429fm 33 23 modify modify VB cord-328210-qhl429fm 33 24 the the DT cord-328210-qhl429fm 33 25 natural natural JJ cord-328210-qhl429fm 33 26 history history NN cord-328210-qhl429fm 33 27 and and CC cord-328210-qhl429fm 33 28 improve improve VB cord-328210-qhl429fm 33 29 the the DT cord-328210-qhl429fm 33 30 quality quality NN cord-328210-qhl429fm 33 31 of of IN cord-328210-qhl429fm 33 32 life life NN cord-328210-qhl429fm 33 33 . . . cord-328210-qhl429fm 34 1 The the DT cord-328210-qhl429fm 34 2 sense sense NN cord-328210-qhl429fm 34 3 of of IN cord-328210-qhl429fm 34 4 smell smell NN cord-328210-qhl429fm 34 5 in in IN cord-328210-qhl429fm 34 6 chronic chronic JJ cord-328210-qhl429fm 34 7 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 34 8 EPOS2020 EPOS2020 NNP cord-328210-qhl429fm 34 9 : : : cord-328210-qhl429fm 35 1 European European NNP cord-328210-qhl429fm 35 2 Position Position NNP cord-328210-qhl429fm 35 3 Paper Paper NNP cord-328210-qhl429fm 35 4 on on IN cord-328210-qhl429fm 35 5 Rhinosinusitis Rhinosinusitis NNP cord-328210-qhl429fm 35 6 and and CC cord-328210-qhl429fm 35 7 Nasal Nasal NNP cord-328210-qhl429fm 35 8 Polyps Polyps NNPS cord-328210-qhl429fm 35 9 2020 2020 CD cord-328210-qhl429fm 35 10 EUFOREA EUFOREA NNP cord-328210-qhl429fm 35 11 consensus consensus NN cord-328210-qhl429fm 35 12 on on IN cord-328210-qhl429fm 35 13 biologics biologic NNS cord-328210-qhl429fm 35 14 for for IN cord-328210-qhl429fm 35 15 CRSwNP CRSwNP VBN cord-328210-qhl429fm 35 16 with with IN cord-328210-qhl429fm 35 17 or or CC cord-328210-qhl429fm 35 18 without without IN cord-328210-qhl429fm 35 19 asthma asthma NN cord-328210-qhl429fm 35 20 Role role NN cord-328210-qhl429fm 35 21 of of IN cord-328210-qhl429fm 35 22 nasal nasal NN cord-328210-qhl429fm 35 23 cytology cytology NN cord-328210-qhl429fm 35 24 Standardization Standardization NNP cord-328210-qhl429fm 35 25 of of IN cord-328210-qhl429fm 35 26 the the DT cord-328210-qhl429fm 35 27 nasal nasal NN cord-328210-qhl429fm 35 28 cytology cytology NN cord-328210-qhl429fm 35 29 in in IN cord-328210-qhl429fm 35 30 the the DT cord-328210-qhl429fm 35 31 work work NN cord-328210-qhl429fm 35 32 - - HYPH cord-328210-qhl429fm 35 33 up up NN cord-328210-qhl429fm 35 34 of of IN cord-328210-qhl429fm 35 35 allergic allergic JJ cord-328210-qhl429fm 35 36 rhinitis rhinitis NN cord-328210-qhl429fm 35 37 Non non JJ cord-328210-qhl429fm 35 38 - - JJ cord-328210-qhl429fm 35 39 surgical surgical JJ cord-328210-qhl429fm 35 40 management management NN cord-328210-qhl429fm 35 41 of of IN cord-328210-qhl429fm 35 42 chronic chronic JJ cord-328210-qhl429fm 35 43 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 35 44 with with IN cord-328210-qhl429fm 35 45 nasal nasal NN cord-328210-qhl429fm 35 46 polyps polyp NNS cord-328210-qhl429fm 35 47 based base VBN cord-328210-qhl429fm 35 48 on on IN cord-328210-qhl429fm 35 49 clinical clinical JJ cord-328210-qhl429fm 35 50 cytological cytological JJ cord-328210-qhl429fm 35 51 grading grading NN cord-328210-qhl429fm 35 52 : : : cord-328210-qhl429fm 35 53 a a DT cord-328210-qhl429fm 35 54 precision precision NN cord-328210-qhl429fm 35 55 medicine medicine NN cord-328210-qhl429fm 35 56 - - HYPH cord-328210-qhl429fm 35 57 based base VBN cord-328210-qhl429fm 35 58 approach approach NN cord-328210-qhl429fm 35 59 Olfactory olfactory JJ cord-328210-qhl429fm 35 60 dysfunction dysfunction NN cord-328210-qhl429fm 35 61 in in IN cord-328210-qhl429fm 35 62 patients patient NNS cord-328210-qhl429fm 35 63 with with IN cord-328210-qhl429fm 35 64 chronic chronic JJ cord-328210-qhl429fm 35 65 rhinosinusitis rhinosinusitis NN cord-328210-qhl429fm 35 66 with with IN cord-328210-qhl429fm 35 67 nasal nasal NN cord-328210-qhl429fm 35 68 polyps polyp NNS cord-328210-qhl429fm 35 69 is be VBZ cord-328210-qhl429fm 35 70 associated associate VBN cord-328210-qhl429fm 35 71 with with IN cord-328210-qhl429fm 35 72 clinical clinical JJ cord-328210-qhl429fm 35 73 - - HYPH cord-328210-qhl429fm 35 74 cytological cytological JJ cord-328210-qhl429fm 35 75 grading grading NN cord-328210-qhl429fm 35 76 severity severity NN