id author title date pages extension mime words sentences flesch summary cache txt cord-335355-lcrbs2op Kunutsor, Setor K. Markers of liver injury and clinical outcomes in COVID-19 patients: A systematic review and meta-analysis 2020-05-28 .txt text/plain 1007 66 50 In this context, we aimed to determine the nature of the relationships of admission levels of five main markers of liver injury (ALT, AST, gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP) and total bilirubin) with the risk of clinical outcomes in patients with COVID-19 using a systematic meta-analysis. MEDLINE, Embase, and The Cochrane library were searched from 2019 to 17 May 2020 for published studies reporting on relationships between admission levels of markers of liver injury (GGT, ALT, AST, ALP and total bilirubin) and clinical outcomes in patients with COVID-19. Taking the overall evidence together, the data supports a higher prevalence of elevated admission levels of markers of liver injury in severe or mortality due to COVID-19 disease, which suggests that patients with elevated levels of liver markers at baseline (during admission) had higher risks of developing worse outcomes in COVID-19. ./cache/cord-335355-lcrbs2op.txt ./txt/cord-335355-lcrbs2op.txt