id author title date pages extension mime words sentences flesch summary cache txt cord-288072-42sx52tn Monto, Arnold S. The Tecumseh Study of Respiratory Illness. VI. Frequency of and Relationship between Outbreaks of Coronavims Infection 1974-03-17 .txt text/plain 3866 213 61 Specimens of blood collected in Tecumseh, Michigan over a four-year period were studied for rise in antibody titer against coronavirus OC43. As part of the study of respiratory infections in Tecumseh, Michigan, specimens of blood were collected on a regular basis from families under surveillance [10] . By testing of specimens collected in early 1967, a large-scale outbreak of infection with coronavirus 229E was detected [11] . All specimens of serum collected from members of 269 families were studied by CF and HAl for rise in titer of antibody to coronavirus OC43. The specimens with rises in CF or HAl titer both showed 66.7% agreement with the neutralization test. Neutralization tests confirmed the difference, and indicated that in the individual case during a period of prevalence of agents related to OC43, even if CF and HAl do not agree, it is likely that an infection with the agent actually did occur. ./cache/cord-288072-42sx52tn.txt ./txt/cord-288072-42sx52tn.txt