id author title date pages extension mime words sentences flesch summary cache txt cord-298372-4pw1y404 Koch, Lionel Natural outbreaks and bioterrorism: How to deal with the two sides of the same coin? 2020-08-18 .txt text/plain 6206 286 42 The last Ebola outbreak in 2014 in West Africa was regarded as a paradigm of the issues caused by emerging infectious diseases nowadays: this extremely deadly pathogen has naturally emerged in a large new area, and its overwhelming spread has subsequently impacted Europe and the United States [3] . At the same time, some natural outbreaks were caused by naturally altered pathogens like the Escherichia coli O104:H4 in Europe in 2011, a strain that acquired and combined unusual virulence factor and drug resistance genes [25] or in 2003 the new human coronavirus (SARS-CoV) identified with surprise in front of severe acute respiratory syndrome cases [26] . Indeed, even if the substantial remaining risk in the case of an attack is the possibility of secondary actions aiming to maximise damages to the emergency infrastructure [38] , the real challenge for global safety remains the early detection, the accurate characterisation and the establishment of specific measures, whatever the outbreak origin [39, 40] . ./cache/cord-298372-4pw1y404.txt ./txt/cord-298372-4pw1y404.txt