id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001340-kqcx7lrq	Ladner, Jason T.	Standards for Sequencing Viral Genomes in the Era of High-Throughput Sequencing	2014-06-17		.txt	text/plain	2512	121	40	Genome sequences play a critical role in our understanding of viral evolution, disease epidemiology, surveillance, diagnosis, and countermeasure development and thus represent valuable resources which must be properly documented and curated to ensure future utility. Here, we outline a set of viral genome quality standards, similar in concept to those proposed for large DNA genomes (4) but focused on the particular challenges of and needs for research on small RNA/ DNA viruses, including characterization of the genomic diversity inherent in all viral samples/populations. Therefore, we have used technology-agnostic criteria to define five standard categories designed to encompass the levels of completeness most often encountered in viral sequencing projects. There is a trend toward requiring a complete genome sequence when a description of a novel virus is being published, and we agree that this is a good goal; however, the amount of time and resources required to complete the last 1 to 2% of a viral genome is often cost and time prohibitive for projects sequencing a large number of samples, and in most cases the very ends of the segments are not essential for proper identification and characterization.	./cache/cord-001340-kqcx7lrq.txt	./txt/cord-001340-kqcx7lrq.txt